Datasets:
manufernandezbur
/
tox_nontox_clustered_2025

Dataset card Data Studio Files
xet
Community
1
Unnamed: 0
int64
2
562k
Entry
stringlengths
6
10
Sequence
stringlengths
11
999
Protein names
stringlengths
5
558
Organism
stringclasses
392 values
Organism (ID)
int64
595
2.89M
Length
int64
11
999
Mass
int64
1.06k
118k
Keywords
stringlengths
4
380
⌀
Gene Ontology IDs
stringlengths
10
754
⌀
Protein existence
stringclasses
5 values
Annotation
float64
1
5
Subcellular location [CC]
stringlengths
30
2.26k
⌀
Signal peptide
stringclasses
677 values
Transmembrane
stringlengths
32
2.52k
⌀
Pfam
stringlengths
8
72
⌀
InterPro
stringlengths
10
180
⌀
PDB
stringlengths
5
2.65k
⌀
Taxonomic lineage
stringclasses
178 values
Gene Names
stringlengths
2
299
⌀
Toxin
bool
2 classes
species
stringclasses
111 values
cdhit_cluster
int64
0
4.65k
cdhit_rep
stringlengths
5
10
cdhit_rep_is_ref
bool
1 class
cdhit_pct_id
float64
81,816
P9WKI1
MSEHQSLPAPEASTEVRVAIVGVGNCASSLVQGVEYYYNADDTSTVPGLMHVRFGPYHVRDVKFVAAFDVDAKKVGFDLSDAIFASENNTIKIADVAPTNVIVQRGPTLDGIGKYYADTIELSDAEPVDVVQALKEAKVDVLVSYLPVGSEEADKFYAQCAIDAGVAFVNALPVFIASDPVWAKKFTDARVPIVGDDIKSQVGATITHRVLAKLFEDRGVQLDRTMQLNVGGNMDFLNMLERERLESKKISKTQAVTSNLKREFKTKDVHIGPSDHVGWLDDRKWAYVRLEGRAFGDVPLNLEYKLEVWDSPNSAGVIIDAVRAAKIAKDRGIGGPVIPASAYLMKSPPEQLPDDIARAQLEEFIIG
Inositol-3-phosphate synthase (IPS) (EC 5.5.1.4) (Myo-inositol 1-phosphate synthase) (MI-1-P synthase) (MIP synthase)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
367
40,094
3D-structure;Acetylation;Inositol biosynthesis;Isomerase;Isopeptide bond;NAD;Reference proteome;Ubl conjugation
GO:0004512; GO:0005829; GO:0006021; GO:0008270; GO:0008654
Evidence at protein level
4
null
null
null
PF01658;
IPR052199;IPR002587;IPR017815;IPR013021;IPR036291;
1GR0;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
ino1 Rv0046c MTCY21D4.09c
false
Mycobacterium tuberculosis
830
row_72262
false
null
112,260
A1KN20
MKVLAAMSGGVDSSVAAARMVDAGHEVVGVHMALSTAPGTLRTGSRGCCSKEDAADARRVADVLGIPFYVWDFAEKFKEDVINDFVSSYARGETPNPCVRCNQQIKFAALSARAVALGFDTVATGHYARLSGGRLRRAVDRDKDQSYVLAVLTAQQLRHAAFPIGDTPKRQIRAEAARRGLAVANKPDSHDICFIPSGNTKAFLGERIGVRRGVVVDADGVVLASHDGVHGFTIGQRRGLGIAGPGPNGRPRYVTAIDADTATVHVGDVTDLDVQTLTGRAPVFTAGAAPSGPVDCVVQVRAHGETVSAVAELIGDALFVQLHAPLRGVARGQTLVLYRPDPAGDEVLGSATIAGASGLSTGGNPGA
tRNA-specific 2-thiouridylase MnmA (EC 2.8.1.13)
Mycobacterium bovis (strain BCG / Pasteur 1173P2)
410,289
367
38,120
ATP-binding;Cytoplasm;Disulfide bond;Nucleotide-binding;RNA-binding;Transferase;tRNA processing;tRNA-binding
GO:0000049; GO:0002143; GO:0005524; GO:0005737; GO:0103016
Inferred from homology
3
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00144}.
null
null
PF03054;PF20258;PF20259;
IPR004506;IPR046885;IPR046884;IPR023382;IPR014729;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype), Mycobacterium tuberculosis variant bovis BCG (no rank)
mnmA trmU BCG_3047c
false
Mycobacterium tuberculosis
831
row_100725
false
null
182,498
O07718
MAIAETDTEVHTPFEQDFEKDVAATQRYFDSSRFAGIIRLYTARQVVEQRGTIPVDHIVAREAAGAFYERLRELFAARKSITTFGPYSPGQAVSMKRMGIEAIYLGGWATSAKGSSTEDPGPDLASYPLSQVPDDAAVLVRALLTADRNQHYLRLQMSERQRAATPAYDFRPFIIADAGTGHGGDPHVRNLIRRFVEVGVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNAARFQLDIMRVPGIIVARTDAEAANLIDSRADERDQPFLLGATKLDVPSYKSCFLAMVRRFTNWASRSSMVIFSMRLATASTRRPAVGLSAKAFSAWSPTRSTRGGRTASSRSTAFSTRSSRGSWRPGRTTRA
Putative isocitrate lyase subunit A (ICL) (EC 4.1.3.1) (Isocitrase) (Isocitratase)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
367
40,490
Lyase;Reference proteome
GO:0004451; GO:0006097; GO:0006102; GO:0046421
Evidence at protein level
3
null
null
null
PF00463;
IPR039556;IPR006254;IPR018523;IPR015813;IPR040442;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
aceAa Rv1915 RVBD_1915 P425_01980
false
Mycobacterium tuberculosis
832
row_169516
false
null
212,636
P9WIS3
MGEGSRRPSGMLMSVDLEPVQLVGPDGTPTAERRYHRDLPEETLRWLYEMMVVTRELDTEFVNLQRQGELALYTPCRGQEAAQVGAAACLRKTDWLFPQYRELGVYLVRGIPPGHVGVAWRGTWHGGLQFTTKCCAPMSVPIGTQTLHAVGAAMAAQRLDEDSVTVAFLGDGATSEGDVHEALNFAAVFTTPCVFYVQNNQWAISMPVSRQTAAPSIAHKAIGYGMPGIRVDGNDVLACYAVMAEAAARARAGDGPTLIEAVTYRLGPHTTADDPTRYRSQEEVDRWATLDPIPRYRTYLQDQGLWSQRLEEQVTARAKHVRSELRDAVFDAPDFDVDEVFTTVYAEITPGLQAQREQLRAELARTD
3-methyl-2-oxobutanoate dehydrogenase subunit alpha (EC 1.2.4.4) (Branched-chain alpha-ketoacid dehydrogenase E1 component subunit alpha) (BCKADH E1-alpha)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
367
40,616
Magnesium;Metal-binding;Oxidoreductase;Reference proteome;Thiamine pyrophosphate
GO:0000287; GO:0003863; GO:0006086
Evidence at protein level
3
null
null
null
PF00676;
IPR050771;IPR001017;IPR017596;IPR029061;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
bkdA pdhA Rv2497c
false
Mycobacterium tuberculosis
833
row_198843
false
null
212,938
P9WN51
MSDVPELIHGPLEDRHRELGASFAEFGGWLMPVSYAGTVSEHNATRTAVGLFDVSHLGKALVRGPGAAQFVNSALTNDLGRIGPGKAQYTLCCTESGGVIDDLIAYYVSDDEIFLVPNAANTAAVVGALQAAAPGGLSITNLHRSYAVLAVQGPCSTDVLTALGLPTEMDYMGYADASYSGVPVRVCRTGYTGEHGYELLPPWESAGVVFDALLAAVSAAGGEPAGLGARDTLRTEMGYPLHGHELSLDISPLQARCGWAVGWRKDAFFGRAALLAEKAAGPRRLLRGLRMVGRGVLRPGLAVLVGDETVGVTTSGTFSPTLQVGIGLALIDSDAGIEDGQQINVDVRGRAVECQVVCPPFVAVKTR
Aminomethyltransferase (EC 2.1.2.10) (Glycine cleavage system T protein)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
367
38,318
Aminotransferase;Reference proteome;Transferase
GO:0004047; GO:0005829; GO:0005960; GO:0008483; GO:0009274; GO:0019464
Evidence at protein level
3
null
null
null
PF01571;PF08669;
IPR006223;IPR022903;IPR013977;IPR006222;IPR028896;IPR029043;IPR027266;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
gcvT Rv2211c MTCY190.22
false
Mycobacterium tuberculosis
834
row_199140
false
null
321,037
A1KGK7
MTYTGSIRCEGDTWDLASSVGATATMVAAARAMATRAANPLINDQFAEPLVRAVGVDVLTRLASGELTASDIDDPERPNASMVRMAEHHAVRTKFFDEFFMDATRAGIRQVVILASGLDSRAYRLAWPAQTVVYEIDQPQVMEFKTRTLAELGATPTADRRVVTADLRADWPTALGAAGFDPTQPTAWSAEGLLRYLPPEAQDRLLDNVTALSVPDSRFATESIRNFKPHHEERMRERMTILANRWRAYGFDLDMNELVYFGDRNEPASYLSDNGWLLTEIKSQDLLTANGFQPFEDEEVPLPDFFYVSARLQRKHRQYPAHRKPAPSWRHTACPVNELSKSAAYTMTRSDAHQASTTAPPPPGLTG
Putative S-adenosyl-L-methionine-dependent methyltransferase BCG_0776c (EC 2.1.1.-)
Mycobacterium bovis (strain BCG / Pasteur 1173P2)
410,289
367
40,876
Methyltransferase;S-adenosyl-L-methionine;Transferase
GO:0008168; GO:0032259
Inferred from homology
2
null
null
null
PF04072;
IPR007213;IPR029063;IPR011610;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype), Mycobacterium tuberculosis variant bovis BCG (no rank)
BCG_0776c
false
Mycobacterium tuberculosis
835
row_304409
false
null
432,229
P9WQC2
MSDGAVVRALVLEAPRRLVVRQYRLPRIGDDDALVRVEACGLCGTDHEQYTGELAGGFAFVPGHETVGTIAAIGPRAEQRWGVSAGDRVAVEVFQSCRQCANCRGGEYRRCVRHGLADMYGFIPVDREPGLWGGYAEYQYLAPDSMVLRVAGDLSPEVATLFNPLGAGIRWGVTIPETKPGDVVAVLGPGIRGLCAAAAAKGAGAGFVMVTGLGPRDADRLALAAQFGADLAVDVAIDDPVAALTEQTGGLADVVVDVTAKAPAAFAQAIALARPAGTVVVAGTRGVGSGAPGFSPDVVVFKELRVLGALGVDATAYRAALDLLVSGRYPFASLPRRCVRLEGAEDLLATMAGERDGVPPIHGVLTP
Probable alcohol dehydrogenase adh (EC 1.1.1.1)
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
83,331
367
37,997
Metal-binding;NAD;Oxidoreductase;Reference proteome;Zinc
GO:0004022; GO:0008270
Inferred from homology
2
null
null
null
PF08240;PF00107;
IPR013149;IPR013154;IPR002328;IPR011032;IPR036291;IPR050129;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
adh MT1581
false
Mycobacterium tuberculosis
836
row_413974
false
null
546,448
P9WFM4
MSASLDDASVAPLVRKTAAWAWRFLVILAAMVALLWVLNKFEVIVVPVLLALMLSALLVPPVDWLDSRGLPHAVAVTLVLLSGFAVLGGILTFVVSQFIAGLPHLVTEVERSIDSARRWLIEGPAHLRGEQIDNAGNAAIEALRNNQAKLTSGALSTAATITELVTAAVLVLFTLIFFLYGGRSIWQYVTKAFPASVRDRVRAAGRAGYASLIGYARATFLVALTDAAGVGAGLAVMGVPLALPLASLVFFGAFIPLIGAVVAGFLAVVVALLAKGIGYALITVGLLIAVNQLEAHLLQPLVMGRAVSIHPLAVVLAIAAGGVLAGVVGALLAVPTVAFFNNAVQVLLGGNPFADVADVSSDHLTEV
Putative transport protein MT0215
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
83,331
367
38,038
Cell membrane;Membrane;Reference proteome;Transmembrane;Transmembrane helix;Transport
GO:0005886; GO:0055085
Inferred from homology
1
SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
null
TRANSMEM 18..38; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 41..61; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 74..94; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 161..181; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 228..248; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 249..269; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 270..290; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 314..334; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 337..357; /note="Helical"; /evidence="ECO:0000255"
PF01594;
IPR002549;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
MT0215
false
Mycobacterium tuberculosis
837
row_526543
false
null
67,965
O07436
MPHWAEERHRRESNYVALEAGLDEGESIRRSEHSRSGCGADAGCWRCRGGPGRGSRRSRRSRGPGGTAGPVDPPAVDLLAPPPDPLALPPALDPLAPPPPDPLAPPPPDPLAVPVAAGPVAGQDPTSFVGPPPFRPPTFNPVDGAMVGVAKPIVINFAVPIADRAMAESAIHISSIPPVPGKFYWMSPTQVRWRPFEFWPANTAVNIDAAGTKSSFRTGDSLVATADDATHQMTITRNGVVQKTFPMSMGMVSGGHQTPNGTYYVLEKFATVVMDSSTYGVPVNSAQGYKLTVSDAVRIDNSGNFVHSAPWSVADQGKRNVTHGCINLSPANAKWFYDNFGSGDPVVVKNSVGTYNKNDGAQDWQI
L,D-transpeptidase 4 (LDT 4) (EC 2.3.2.-) (Ldt(Mt4))
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
366
38,904
Acyltransferase;Cell shape;Cell wall biogenesis/degradation;Peptidoglycan synthesis;Reference proteome;Transferase
GO:0005576; GO:0008360; GO:0016746; GO:0018104; GO:0071555; GO:0071972
Evidence at protein level
4
null
null
null
PF17964;PF03734;
IPR041280;IPR050979;IPR005490;IPR038063;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
Rv0192 RVBD_0192 P425_00200
false
Mycobacterium tuberculosis
838
row_59057
false
null
207,794
P65627
MSLLFDFFSLDFIYYPVSWIMWVWYRLFAFVLGPSNFFAWALSVMFLVFTLRALLYKPFVRQIRTTRQMQELQPQIKALQKKYGKDRQRMALEMQKLQREHGFNPILGCLPMLAQIPVFLGLYHVLRSFNRTTGGFGQPHLSVIENRLTGNYVFSPVDVGHFLDANLFGAPIGAYMTQRSGLDAFVDFSRPALIAVGVPVMILAGIATYFNSRASIARQSAEAAANPQTAMMNKLALYVFPLGVVVGGPFLPLAIILYWFSNNIWTFGQQHYVFGMIEKEEEAKKQEAVRRRAANAPAPGAKPKRSPKTAPATNAAAPTEAGDTDDGAESDASTERPADTSNPARRNSGPSARTPRPGVRPKKRKR
Membrane protein insertase YidC (Foldase YidC) (Membrane integrase YidC) (Membrane protein YidC)
Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
233,413
366
40,916
Cell membrane;Chaperone;Membrane;Protein transport;Reference proteome;Transmembrane;Transmembrane helix;Transport
GO:0005886; GO:0015031; GO:0032977; GO:0051205
Inferred from homology
3
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
null
TRANSMEM 3..23; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 28..48; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 106..126; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 191..211; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 237..257; /note="Helical"; /evidence="ECO:0000255"
PF02096;
IPR001708;IPR028055;IPR047196;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype)
yidC BQ2027_MB3952C
false
Mycobacterium tuberculosis
839
row_194216
false
null
528,439
A1KMV2
MEETSVAGDPGPDAGTSTAPNAAPEPVARRQRILFVGEAATLAHVVRPFVLARSLDPSRYEVHFACDPRFNKLLGPLPFPHHPIHTVPSEEVLLKIAQGRLFYNTRTLRKYIAADRKILNEIAPDVVVGDNRLSLSVSARLAGIPYIAIANAYWSPQARRRFPLPDVPWTRFFGVRPVSILYRLYRPLIFALYCLPLNWLRRKHGLSSLGWDLCRIFTDGDYTLYADVPELVPTYNLPANHRYLGPVLWSPDVKPPTWWHSLPTDRPIIYATLGSSGGKNLLQVVLNALGRFTRDGDRGHRWPEPPEERAGQRLRRGLPAGRSGCSALRRGALQRRQPDDAAGVGGRGAGDRAPQQHGPALEHGGP
Inactive PGL/p-HBAD biosynthesis glycosyltransferase BCG_2979c
Mycobacterium bovis (strain BCG / Pasteur 1173P2)
410,289
366
40,668
null
null
Inferred from homology
1
null
null
null
null
null
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype), Mycobacterium tuberculosis variant bovis BCG (no rank)
BCG_2979c
false
Mycobacterium tuberculosis
840
row_508775
false
null
112,270
A1KP00
MTAAPTLQTIRLAPKALLHDHLDGGLRPATVLDIAGQVGYDDLPATDVDALASWFRTQSHSGSLERYLEPFSHTVAVMQTPEALYRVAFECAQDLAADSVVYAEVRFAPELHISCGLSFDDVVDTVLTGFAAGEKACAADGQPITVRCLVTAMRHAAMSREIAELAIRFRDKGVVGFDIAGAEAGHPPTRHLDAFEYMRDHNARFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDDIDVDADGGFQLGRLAAILRDKRIPLELCPSSNVQTGAVASIAEHPFDLLARARFRVTVNTDNRLMSDTSMSLEMHRLVEAFGYGWSDLARFTVNAMKSAFIPFDQRLAIIDEVIKPRFAALMGHSE
Adenosine deaminase (EC 3.5.4.4) (Adenosine aminohydrolase)
Mycobacterium bovis (strain BCG / Pasteur 1173P2)
410,289
365
39,743
Hydrolase;Metal-binding;Nucleotide metabolism;Zinc
GO:0004000; GO:0005829; GO:0006154; GO:0008270; GO:0009117; GO:0009168; GO:0043103; GO:0046103; GO:0046936
Inferred from homology
3
null
null
null
PF00962;
IPR028893;IPR001365;IPR006330;IPR032466;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype), Mycobacterium tuberculosis variant bovis BCG (no rank)
add BCG_3379c
false
Mycobacterium tuberculosis
841
row_100735
false
null
431,457
P9WI13
MDFGALPPEINSGRMYCGPGSGPMLAAAAAWDGVAVELGLAATGYASVIAELTGAPWVGAASLSMVAAATPYVAWLSQAAARAEQAGMQAAAAAAAYEAAFVMTVPPPVITANRVLVMTLIATNFFGQNSAAIAVAEAQYAEMWAQDAVAMYGYAAASASASRLIPFAAPPKTTNSAGVVAQVAAVAAMPGLLQRLSSAASVSWSNPNDWWLVRLLGSITPTERTTIVRLLGQSYFATGMAQFFASIAQQLTFGPGGTTAGSGGAWYPTPQFAGLGASRAVSASLARANKIGALSVPPSWVKTTALTESPVAHAVSANPTVGSSHGPHGLLRGLPLGSRITRRSGAFAHRYGFRHSVVARPPSAG
Uncharacterized PPE family protein PPE25
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
365
37,090
Reference proteome
GO:0035435; GO:0052572
Inferred from homology
2
null
null
null
PF00823;PF12484;
IPR022171;IPR000030;IPR038332;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
PPE25 Rv1787
false
Mycobacterium tuberculosis
842
row_413216
false
null
26,912
P9WLH5
MKVVIEADGGSRGNPGPAGYGAVVWTADHSTVLAESKQAIGRATNNVAEYRGLIAGLDDAVKLGATEAAVLMDSKLVVEQMSGRWKVKHPDLLKLYVQAQALASQFRRINYEWVPRARNTYADRLANDAMDAAAQSAAADADPAKIVATESPTSPGWTGARGTPTRLLLLRHGQTELSEQRRYSGRGNPGLNEVGWRQVGAAAGYLARRGGIAAVVSSPLQRAYDTAVTAARALALDVVVDDDLVETDFGAWEGLTFAEAAERDPELHRRWLQDTSITPPGGESFDDVLRRVRRGRDRIIVGYEGATVLVVSHVTPIKMLLRLALDAGSGVLYRLHLDLASLSIAEFYADGASSVRLVNQTGYL
Bifunctional protein Rv2228c [Includes: Ribonuclease H (EC 3.1.26.4); Adenosylcobalamin/alpha-ribazole phosphatase (EC 3.1.3.73)]
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
364
39,145
3D-structure;Endonuclease;Hydrolase;Magnesium;Metal-binding;Multifunctional enzyme;Nuclease;Reference proteome
GO:0004523; GO:0006401; GO:0009236; GO:0032296; GO:0043755; GO:0046872; GO:0071667
Evidence at protein level
5
null
null
null
PF00300;PF13456;
IPR013078;IPR029033;IPR050275;IPR012337;IPR014636;IPR002156;IPR036397;
3HST;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
Rv2228c MTCY427.09c
false
Mycobacterium tuberculosis
843
row_23553
false
null
60,929
A1KMM4
MVPELMFDEPRPGRPPRHLADLDAAGRASAVAELGLPAFRAKQLAHQYYGRLIADPRQMTDLPAAVRDRIAGAMFPNLLTASADITCDAGQTRKTLWRAVDGTMFESVLMRYPRRNTVCISSQAGCGMACPFCATGQGGLTRNLSTAEILEQVRAGAAALRDDFGDRLSNVVFMGMGEPLANYARVLAAVQRITARPPSGFGISARAVTVSTVGLAPAIRNLADARLGVTLALSLHAPDDGLRDTLVPVNNRWRISEALDAARYYANVTGRRVSIEYALIRDVNDQPWRADLLGKRLHRVLGPLAHVNLIPLNPTPGSDWDASPKPVEREFVKRVRAKGVSCTVRDTRGREISAACGQLAAVGG
Probable dual-specificity RNA methyltransferase RlmN (EC 2.1.1.192) (23S rRNA (adenine(2503)-C(2))-methyltransferase) (23S rRNA m2A2503 methyltransferase) (Ribosomal RNA large subunit methyltransferase N) (tRNA (adenine(37)-C(2))-methyltransferase) (tRNA m2A37 methyltransferase)
Mycobacterium bovis (strain BCG / Pasteur 1173P2)
410,289
364
39,255
4Fe-4S;Cytoplasm;Disulfide bond;Iron;Iron-sulfur;Metal-binding;Methyltransferase;rRNA processing;S-adenosyl-L-methionine;Transferase;tRNA processing
GO:0000049; GO:0002935; GO:0005737; GO:0019843; GO:0030488; GO:0046872; GO:0051539; GO:0070040; GO:0070475
Inferred from homology
4
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01849}.
null
null
PF04055;
IPR013785;IPR040072;IPR027492;IPR004383;IPR007197;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype), Mycobacterium tuberculosis variant bovis BCG (no rank)
rlmN BCG_2901c
false
Mycobacterium tuberculosis
844
row_52704
false
null
81,945
P9WQ89
MLWILGPHTGPLLFDAVASLDTSPLAAARYHGDQDVAPGVLDFAVNVRHDRPPEWLVRQLAALLPELARYPSTDDVHRAQDAVAERHGRTRDEVLPLVGAAEGFALLHNLSPVRAAIVVPAFTEPAIALSAAGITAHHVVLKPPFVLDTAHVPDDADLVVVGNPTNPTSVLHLREQLLELRRPGRILVVDEAFADWVPGEPQSLADDSLPDVLVLRSLTKTWSLAGLRVGYALGSPDVLARLTVQRAHWPLGTLQLTAIAACCAPRAVAAAAADAVRLTALRAEMVAGLRSVGAEVVDGAAPFVLFNIADADGLRNYLQSKGIAVRRGDTFVGLDARYLRAAVRPEWPVLVAAIAEWAKRGGRR
Histidinol-phosphate aminotransferase Rv2231c (HspAT) (EC 2.6.1.9)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
364
38,937
Aminotransferase;Cell wall;Pyridoxal phosphate;Reference proteome;Secreted;Transferase
GO:0004400; GO:0005576; GO:0009058; GO:0030170
Evidence at protein level
4
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:38698289}. Secreted, cell wall {ECO:0000269|PubMed:38698289}.
null
null
PF00155;
IPR004839;IPR004838;IPR015424;IPR015421;IPR015422;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
Rv2231c MTCY427.12c
false
Mycobacterium tuberculosis
845
row_72382
false
null
112,139
A1KG98
MTVSYGAPGRVNLIGEHTDYNLGFALPIALPRRTVVTFTPEHTGAITARSDRADGSARIPLDTTPGQVTGWAAYAAGAIWALRGAGHPVPGGAMSITSDVEIGSGLSSSAALIGAVLGAVGAATGTRIDRLERARLAQRAENDYVGAPTGLLDHLAALFGAPKTALLIDFRDITVRPVAFDPDACDVVLLLMDSRARHRHAGGEYALRRASCERAAADLGVSSLRAVQDRGLAALGAIADPIDARRARHVLTENQRVLDFAAALADSDFTAAGQLLTASHESMREDFAITTERIDLIAESAVRAGALGARMTGGGFGGAVIALVPADRARDVADTVRRAAVTAGYDEPAVSRTYAAPGAAECC
Galactokinase (EC 2.7.1.6) (Galactose kinase)
Mycobacterium bovis (strain BCG / Pasteur 1173P2)
410,289
363
37,572
ATP-binding;Carbohydrate metabolism;Cytoplasm;Galactose metabolism;Kinase;Magnesium;Metal-binding;Nucleotide-binding;Transferase
GO:0000287; GO:0004335; GO:0005524; GO:0005829; GO:0006012
Inferred from homology
3
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00246}.
null
null
PF10509;PF08544;PF00288;
IPR000705;IPR022963;IPR019741;IPR019539;IPR013750;IPR036554;IPR006204;IPR006206;IPR020568;IPR014721;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype), Mycobacterium tuberculosis variant bovis BCG (no rank)
galK BCG_0666
false
Mycobacterium tuberculosis
846
row_100606
false
null
126,069
A5U003
MTVSYGAPGRVNLIGEHTDYNLGFALPIALPRRTVVTFTPEHTGAITARSDRADGSARIPLDTTPGQVTGWAAYAAGAIWALRGAGHPVPGGAMSITSDVEIGSGLSSSAALIGAVLGAVGAATGTRIDRLERARLAQRAENDYVGAPTGLLDHLAALFGAPKTALLIDFRDITVRPVAFDPDACDVVLLLMDSRARHCHAGGEYALRRASCERAAADLGVSSLRAVQDRGLAALGAIADPIDARRARHVLTENQRVLDFAAALADSDFTAAGQLLTASHESMREDFAITTERIDLIAESAVRAGALGARMTGGGFGGAVIALVPADRARDVADTVRRAAVTAGYDEPAVSRTYAAPGAAECR
Galactokinase (EC 2.7.1.6) (Galactose kinase)
Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra)
419,947
363
37,572
ATP-binding;Carbohydrate metabolism;Cytoplasm;Galactose metabolism;Kinase;Magnesium;Metal-binding;Nucleotide-binding;Reference proteome;Transferase
GO:0000287; GO:0004335; GO:0005524; GO:0005829; GO:0006012
Inferred from homology
3
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00246}.
null
null
PF10509;PF08544;PF00288;
IPR000705;IPR022963;IPR019741;IPR019539;IPR013750;IPR036554;IPR006204;IPR006206;IPR020568;IPR014721;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
galK MRA_0629
false
Mycobacterium tuberculosis
847
row_114253
false
null
207,392
P63855
MTPRGPGRLQRLSQCRPQRGSGGPARGLRQLALAAMLGALAVTVSGCSWSEALGIGWPEGITPEAHLNRELWIGAVIASLAVGVIVWGLIFWSAVFHRKKNTDTELPRQFGYNMPLELVLTVIPFLIISVLFYFTVVVQEKMLQIAKDPEVVIDITSFQWNWKFGYQRVNFKDGTLTYDGADPERKRAMVSKPEGKDKYGEELVGPVRGLNTEDRTYLNFDKVETLGTSTEIPVLVLPSGKRIEFQMASADVIHAFWVPEFLFKRDVMPNPVANNSVNVFQIEEITKTGAFVGHCAEMCGTYHSMMNFEVRVVTPNDFKAYLQQRIDGKTNAEALRAINQPPLAVTTHPFDTRRGELAPQPVG
Cytochrome c oxidase subunit 2 (EC 7.1.1.9) (Cytochrome aa3 subunit 2) (Cytochrome c oxidase polypeptide II)
Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
233,413
363
40,480
Cell membrane;Copper;Electron transport;Heme;Iron;Membrane;Metal-binding;Reference proteome;Respiratory chain;Signal;Translocase;Transmembrane;Transmembrane helix;Transport
GO:0004129; GO:0005507; GO:0005886; GO:0042773
Inferred from homology
3
SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
SIGNAL 1..41; /evidence="ECO:0000255"
TRANSMEM 71..91; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 118..138; /note="Helical"; /evidence="ECO:0000255"
PF00116;
IPR045187;IPR002429;IPR001505;IPR008972;IPR036257;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype)
ctaC BQ2027_MB2223C
false
Mycobacterium tuberculosis
848
row_193815
false
null
26,720
P9WG29
MLRLVVGALLLVLAFAGGYAVAACKTVTLTVDGTAMRVTTMKSRVIDIVEENGFSVDDRDDLYPAAGVQVHDADTIVLRRSRPLQISLDGHDAKQVWTTASTVDEALAQLAMTDTAPAAASRASRVPLSGMALPVVSAKTVQLNDGGLVRTVHLPAPNVAGLLSAAGVPLLQSDHVVPAATAPIVEGMQIQVTRNRIKKVTERLPLPPNARRVEDPEMNMSREVVEDPGVPGTQDVTFAVAEVNGVETGRLPVANVVVTPAHEAVVRVGTKPGTEVPPVIDGSIWDAIAGCEAGGNWAINTGNGYYGGVQFDQGTWEANGGLRYAPRADLATREEQIAVAEVTRLRQGWGAWPVCAARAGAR
Resuscitation-promoting factor RpfB (EC 3.-.-.-)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
362
38,078
3D-structure;Cell membrane;Disulfide bond;Hydrolase;Lipoprotein;Membrane;Palmitate;Reference proteome;Signal;Virulence
GO:0005576; GO:0005886; GO:0009372; GO:0010628; GO:0010629; GO:0016787; GO:0042127; GO:0085016
Evidence at protein level
5
SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|PROSITE-ProRule:PRU00303}; Lipid-anchor {ECO:0000255|PROSITE-ProRule:PRU00303}. Note=Localizes to the septa upon expression in M.smegmatis. {ECO:0000269|PubMed:17919286}.
SIGNAL 1..23; /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
null
PF03990;PF07501;PF06737;
IPR007137;IPR011098;IPR023346;IPR051933;IPR010618;
1XSF;3EO5;4EMN;4KL7;4KPM;5E27;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
rpfB Rv1009 MTC1237.26
false
Mycobacterium tuberculosis
849
row_23367
false
null
26,952
P9WN21
MTAEGSGSSTAAVASHDPSHTRPSRREAPDRNLAMELVRVTEAGAMAAGRWVGRGDKEGGDGAAVDAMRELVNSVSMRGVVVIGEGEKDHAPMLYNGEEVGNGDGPECDFAVDPIDGTTLMSKGMTNAISVLAVADRGTMFDPSAVFYMNKIAVGPDAAHVLDITAPISENIRAVAKVKDLSVRDMTVCILDRPRHAQLIHDVRATGARIRLITDGDVAGAISACRPHSGTDLLAGIGGTPEGIIAAAAIRCMGGAIQAQLAPRDDAERRKALEAGYDLNQVLTTEDLVSGENVFFCATGVTDGDLLKGVRYYPGGCTTHSIVMRSKSGTVRMIEAYHRLSKLNEYSAIDFTGDSSAVYPLP
Fructose-1,6-bisphosphatase class 2 (FBPase class 2) (EC 3.1.3.11) (D-fructose-1,6-bisphosphate 1-phosphohydrolase class 2) (Fructose 1,6-bisphosphatase II)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
362
38,084
3D-structure;Acetylation;Carbohydrate metabolism;Cytoplasm;Direct protein sequencing;Gluconeogenesis;Hydrolase;Manganese;Metal-binding;Reference proteome
GO:0005829; GO:0006071; GO:0006094; GO:0030388; GO:0042132; GO:0046872
Evidence at protein level
5
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
null
null
PF03320;
IPR004464;
6AYU;6AYV;6AYY;7TXB;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
glpX Rv1099c
false
Mycobacterium tuberculosis
850
row_23592
false
null
81,933
P9WPX9
MTDIGAPVTVQVAVDPPYPVVIGTGLLDELEDLLADRHKVAVVHQPGLAETAEEIRKRLAGKGVDAHRIEIPDAEAGKDLPVVGFIWEVLGRIGIGRKDALVSLGGGAATDVAGFAAATWLRGVSIVHLPTTLLGMVDAAVGGKTGINTDAGKNLVGAFHQPLAVLVDLATLQTLPRDEMICGMAEVVKAGFIADPVILDLIEADPQAALDPAGDVLPELIRRAITVKAEVVAADEKESELREILNYGHTLGHAIERRERYRWRHGAAVSVGLVFAAELARLAGRLDDATAQRHRTILSSLGLPVSYDPDALPQLLEIMAGDKKTRAGVLRFVVLDGLAKPGRMVGPDPGLLVTAYAGVCAP
3-dehydroquinate synthase (DHQS) (EC 4.2.3.4)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
362
38,119
3D-structure;Amino-acid biosynthesis;Aromatic amino acid biosynthesis;Cobalt;Cytoplasm;Lyase;Metal-binding;NAD;Nucleotide-binding;Reference proteome;Zinc
GO:0000166; GO:0003856; GO:0005507; GO:0005829; GO:0005886; GO:0008270; GO:0008652; GO:0009073; GO:0009274; GO:0009423
Evidence at protein level
4
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00110}.
null
null
PF01761;PF24621;
IPR050071;IPR016037;IPR030963;IPR030960;IPR056179;
3QBD;3QBE;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
aroB Rv2538c MTCY159.18
false
Mycobacterium tuberculosis
851
row_72371
false
null
321,110
A1KKP9
MIGFAPVSTPDAAAEAAARARQDSLTKPRGALGSLEDLSVWVASCQQRCPPRQFERARVVVFAGDHGVARSGVSAYPPEVTAQMVANIDAGGAAINALADVAGATVRVADLAVDADPLSERIGAHKVRRGSGNIATEDALTNDETAAAITAGQQIADEEVDAGADLLIAGDMGIGNTTAAAVLVAALTDAEPVAVVGFGTGIDDAGWARKTAAVRDALFRVRPVLPDPVGLLRCAGGADLAAIAGFCAQAAVRRTPLLLDGVAVTAAALVAERLAPGAHRWWQAGHRSSEPGHGLALAALGLDPIVDLHMRLGEGTGAAVALMVLRAAVAALSSMATFTEAGVSTRSVDGVDRTAPPAVSP
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (NN:DBI PRT) (EC 2.4.2.21) (N(1)-alpha-phosphoribosyltransferase)
Mycobacterium bovis (strain BCG / Pasteur 1173P2)
410,289
361
36,411
Cobalamin biosynthesis;Glycosyltransferase;Transferase
GO:0008939; GO:0009236
Inferred from homology
2
null
null
null
PF02277;
IPR003200;IPR017846;IPR023195;IPR036087;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype), Mycobacterium tuberculosis variant bovis BCG (no rank)
cobT BCG_2223
false
Mycobacterium tuberculosis
852
row_304482
false
null
4,621
O06543
MAGPLSGLRVVELAGIGPGPHAAMILGDLGADVVRIDRPSSVDGISRDAMLRNRRIVTADLKSDQGLELALKLIAKADVLIEGYRPGVTERLGLGPEECAKVNDRLIYARMTGWGQTGPRSQQAGHDINYISLNGILHAIGRGDERPVPPLNLVGDFGGGSMFLLVGILAALWERQSSGKGQVVDAAMVDGSSVLIQMMWAMRATGMWTDTRGANMLDGGAPYYDTYECADGRYVAVGAIEPQFYAAMLAGLGLDAAELPPQNDRARWPELRALLTEAFASHDRDHWGAVFANSDACVTPVLAFGEVHNEPHIIERNTFYEANGGWQPMPAPRFSRTASSQPRPPAATIDIEAVLTDWDG
Alpha-methylacyl-CoA racemase (AMACR) (EC 5.1.99.4) (MtMCR)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
360
38,685
3D-structure;Isomerase;Lipid metabolism;Reference proteome
GO:0006629; GO:0006637; GO:0008111; GO:0042803
Evidence at protein level
5
null
null
null
PF02515;
IPR050509;IPR003673;IPR044855;IPR023606;
1X74;2GCE;2GCI;2GD0;2GD2;2GD6;2YIM;8RMW;8RP3;8RP4;8RP5;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
mcr Rv1143
false
Mycobacterium tuberculosis
853
row_3701
false
null
26,729
P9WG59
MTVPPTATHQPWPGVIAAYRDRLPVGDDWTPVTLLEGGTPLIAATNLSKQTGCTIHLKVEGLNPTGSFKDRGMTMAVTDALAHGQRAVLCASTGNTSASAAAYAARAGITCAVLIPQGKIAMGKLAQAVMHGAKIIQIDGNFDDCLELARKMAADFPTISLVNSVNPVRIEGQKTAAFEIVDVLGTAPDVHALPVGNAGNITAYWKGYTEYHQLGLIDKLPRMLGTQAAGAAPLVLGEPVSHPETIATAIRIGSPASWTSAVEAQQQSKGRFLAASDEEILAAYHLVARVEGVFVEPASAASIAGLLKAIDDGWVARGSTVVCTVTGNGLKDPDTALKDMPSVSPVPVDPVAVVEKLGLA
Threonine synthase (TS) (EC 4.2.3.1)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
360
37,322
3D-structure;Acetylation;Amino-acid biosynthesis;Isopeptide bond;Lyase;Pyridoxal phosphate;Reference proteome;Threonine biosynthesis;Ubl conjugation
GO:0004795; GO:0005737; GO:0005829; GO:0005886; GO:0009088; GO:0019344; GO:0030170
Evidence at protein level
5
null
null
null
PF00291;
IPR050147;IPR000634;IPR004450;IPR026260;IPR001926;IPR036052;
2D1F;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
thrC Rv1295 MTCY373.15
false
Mycobacterium tuberculosis
854
row_23376
false
null
81,539
P96809
MTGISRRTFGLAAGFGAIGAGGLGGGCSTRSGPTPTPEPASRGVGVVLSHEQFRTDRLVAHAQAAEQAGFRYVWASDHLQPWQDNEGHSMFPWLTLALVGNSTSSILFGTGVTCPIYRYHPATVAQAFASLAILNPGRVFLGLGTGERLNEQAATDTFGNYRERHDRLIEAIVLIRQLWSGERISFTGHYFRTDELKLYDTPAMPPPIFVAASGPQSATLAGRYGDGWIAQARDINDAKLLAAFAAGAQAAGRDPTTLGKRAELFAVVGDDKAAARAADLWRFTAGAVDQPNPVEIQRAAESNPIEKVLANWAVGTDPGVHIGAVQAVLDAGAVPFLHFPQDDPITAIDFYRTNVLPELR
F420-dependent hydroxymycolic acid dehydrogenase (fHMAD) (EC 1.1.98.-) (FGD2)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
360
38,445
Lipid biosynthesis;Lipid metabolism;Oxidoreductase;Reference proteome;Signal
GO:0005886; GO:0006629; GO:0016705; GO:0030313
Evidence at protein level
4
SUBCELLULAR LOCATION: Cell envelope {ECO:0000269|PubMed:23110042}. Note=The Rv0132c-F420 complex is translocated via the Tat pathway across the cytoplasmic membrane, where Rv0132c is anchored to the cell envelope. {ECO:0000269|PubMed:23110042}.
SIGNAL 1..40; /note="Tat-type signal"; /evidence="ECO:0000255|PROSITE-ProRule:PRU00648"
null
PF00296;
IPR050564;IPR031017;IPR019945;IPR011251;IPR036661;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
fgd2 Rv0132c
false
Mycobacterium tuberculosis
855
row_72008
false
null
207,689
P65385
MTLTALGMPALRSRTNGIADPRVVPTTGPLVDTFGRVANDLRVSLTDRCNLRCSYCMPERGLRWLPGEQLLRPDELARLIHIAVTRLGVTSVRFTGGEPLLAHHLDEVVAATARLRPRPEISLTTNGVGLARRAGALAEAGLDRVNVSLDSIDRAHFAAITRRDRLAHVLAGLAAAKAAGLTPVKVNAVLDPTTGREDVVDLLRFCLERGYQLRVIEQMPLDAGHSWRRNIALSADDVLAALRPHFRLRPDPAPRGSAPAELWLVDAGPNTPRGRFGVIASVSHAFCSTCDRTRLTADGQIRSCLFSTEETDLRRLLRGGADDDAIEAAWRAAMWSKPAGHGINAPDFIQPDRPMSAIGG
GTP 3',8-cyclase 2 (EC 4.1.99.22) (Molybdenum cofactor biosynthesis protein A 2)
Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
233,413
360
38,986
4Fe-4S;GTP-binding;Iron;Iron-sulfur;Lyase;Metal-binding;Molybdenum cofactor biosynthesis;Nucleotide-binding;Reference proteome;S-adenosyl-L-methionine
GO:0005525; GO:0006777; GO:0046872; GO:0051539; GO:0061798; GO:0061799; GO:1904047
Inferred from homology
3
null
null
null
PF06463;PF04055;
IPR013785;IPR006638;IPR013483;IPR000385;IPR010505;IPR050105;IPR007197;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype)
moaA2 BQ2027_MB0893C
false
Mycobacterium tuberculosis
856
row_194111
false
null
426,803
P67099
MPAPAALRVRGSSSPRVALALGSGGARGYAHIGVIQALRERGYDIVGIAGSSMGAVVGGVHAAGRLDEFAHWAKSLTQRTILRLLDPSISAAGILRAEKILDAVRDIVGPVAIEQLPIPYTAVATDLLAGKSVWFQRGPLDAAIRASIAIPGVIAPHEVDGRLLADGGILDPLPMAPIAGVNADLTIAVSLNGSEAGPARDAEPNVTAEWLNRMVRSTSALFDVSAARSLLDRPTARAVLSRFGAAAAESDSWSQAPEIEQRPAGPPADREEAADTPGLPKMGSFEVMNRTIDIAQSALARHTLAGYPADLLIEVPRSTCRSLEFHRAVEVIAVGRALATQALEAFEIDDDESAAATIEG
Uncharacterized NTE family protein Mb1092c
Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
233,413
360
37,523
Hydrolase;Lipid degradation;Lipid metabolism;Reference proteome
GO:0004622; GO:0016042; GO:0046470
Inferred from homology
2
null
null
null
PF01734;
IPR016035;IPR001423;IPR050301;IPR002641;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype)
BQ2027_MB1092C
false
Mycobacterium tuberculosis
857
row_408897
false
null
26,898
P9WKH1
MRGTDEKYGLPPQPDSDRMTRRTLPVLGLAHELITPTLRQMADRLDPHMRPVVSYHLGWSDERGRPVNNNCGKAIRPALVFVAAEAAGADPHSAIPGAVSVELVHNFSLVHDDLMDRDEHRRHRPTVWALWGDAMALLAGDAMLSLAHEVLLDCDSPHVGAALRAISEATRELIRGQAADTAFESRTDVALDECLKMAEGKTAALMAASAEVGALLAGAPRSVREALVAYGRHIGLAFQLVDDLLGIWGRPEITGKPVYSDLRSRKKTLPVTWTVAHGGSAGRRLAAWLVDETGSQTASDDELAAVAELIECGGGRRWASAEARRHVTQGIDMVARIGIPDRPAAELQDLAHYIVDRQA
(2E,6E)-farnesyl diphosphate synthase (E,E-FPP synthase) (FPP synthase) (EC 2.5.1.10)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
359
38,852
Cytoplasm;Lipid biosynthesis;Lipid metabolism;Magnesium;Metal-binding;Reference proteome;Transferase
GO:0000287; GO:0004161; GO:0004337; GO:0004659; GO:0005506; GO:0005737; GO:0008299; GO:0030145; GO:0033384; GO:0033386; GO:0045337
Evidence at protein level
5
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:15060088}.
null
null
PF00348;
IPR008949;IPR000092;IPR033749;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
Rv3398c MTCY78.30
false
Mycobacterium tuberculosis
858
row_23539
false
null
67,720
L7N6A5
MATHQVDAVVLVGGKGTRLRPLTLSAPKPMLPTAGLPFLTHLLSRIAAAGIEHVILGTSYKPAVFEAEFGDGSALGLQIEYVTEEHPLGTGGGIANVAGKLRNDTAMVFNGDVLSGADLAQLLDFHRSNRADVTLQLVRVGDPRAFGCVPTDEEDRVVAFLEKTEDPPTDQINAGCYVFERNVIDRIPQGREVSVEREVFPALLADGDCKIYGYVDASYWRDMGTPEDFVRGSADLVRGIAPSPALRGHRGEQLVHDGAAVSPGALLIGGTVVGRGAEIGPGTRLDGAVIFDGVRVEAGCVIERSIIGFGARIGPRALIRDGVIGDGADIGARCELLSGARVWPGVFLPDGGIRYSSDV
Mannose-1-phosphate guanylyltransferase (EC 2.7.7.13) (GDP-mannose pyrophosphorylase) (GMP) (GMPP)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
359
37,857
Cell wall biogenesis/degradation;GTP-binding;Nucleotide-binding;Nucleotidyltransferase;Reference proteome;Transferase
GO:0005525; GO:0005737; GO:0009298; GO:0016779; GO:0071555
Evidence at protein level
4
null
null
null
PF00483;
IPR050486;IPR005835;IPR029044;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
manB Rv3264c
false
Mycobacterium tuberculosis
859
row_58825
false
null
69,130
O50440
MKRVIAGAFAVWLVGWAGGFGTAIAASEPAYPWAPGPPPSPSPVGDASTAKVVYALGGARMPGIPWYEYTNQAGSQYFPNAKHDLIDYPAGAAFSWWPTMLLPPGSHQDNMTVGVAVKDGTNSLDNAIHHGTDPAAAVGLSQGSLVLDQEQARLANDPTAPAPDKLQFTTFGDPTGRHAFGASFLARIFPPGSHIPIPFIEYTMPQQVDSQYDTNHVVTAYDGFSDFPDRPDNLLAVANAAIGAAIAHTPIGFTGPGDVPPQNIRTTVNSRGATTTTYLVPVNHLPLTLPLRYLGMSDAEVDQIDSVLQPQIDAAYARNDNWFTRPVSVDPVRGLDPLTAPGSIVEGARGLLGSPAFGG
Diacyltrehalose acyltransferase Chp2 (EC 2.3.1.-)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
359
37,818
Acyltransferase;Cell inner membrane;Cell membrane;Lipid biosynthesis;Lipid metabolism;Membrane;Reference proteome;Transferase;Transmembrane;Transmembrane helix
GO:0005886; GO:0006629; GO:0009274; GO:0016746
Evidence at protein level
4
SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000269|PubMed:25124040, ECO:0000269|PubMed:25331437}; Single-pass membrane protein {ECO:0000255}.
null
TRANSMEM 4..24; /note="Helical"; /evidence="ECO:0000255"
PF08237;
IPR013228;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
chp2 Rv1184c RVBD_1184c P425_01234
false
Mycobacterium tuberculosis
860
row_60135
false
null
81,788
P9WJS3
MSTPTLPDMVAPSPRVRVKDRCRRMMGDLRLSVIDQCNLRCRYCMPEEHYTWLPRQDLLSVKEISAIVDVFLSVGVSKVRITGGEPLIRPDLPEIVRTLSAKVGEDSGLRDLAITTNGVLLADRVDGLKAAGMKRITVSLDTLQPERFKAISQRNSHDKVIAGIKAVAAAGFTDTKIDTTVMRGANHDELADLIEFARTVNAEVRFIEYMDVGGATHWAWEKVFTKANMLESLEKRYGRIEPLPKHDTAPANRYALPDGTTFGIIASTTEPFCATCDRSRLTADGLWLHCLYAISGINLREPLRAGATHDDLVETVTTGWRRRTDRGAEQRLAQRERGVFLPLSTLKADPHLEMHTRGG
GTP 3',8-cyclase 1 (EC 4.1.99.22) (Molybdenum cofactor biosynthesis protein A 1)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
359
39,960
4Fe-4S;GTP-binding;Iron;Iron-sulfur;Lyase;Metal-binding;Molybdenum cofactor biosynthesis;Nucleotide-binding;Reference proteome;S-adenosyl-L-methionine
GO:0005525; GO:0005886; GO:0006777; GO:0046872; GO:0051539; GO:0061798; GO:0061799; GO:1904047
Evidence at transcript level
4
null
null
null
PF06463;PF04055;
IPR013785;IPR006638;IPR013483;IPR000385;IPR010505;IPR050105;IPR007197;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
moaA1 moaA Rv3109 MTCY164.19
false
Mycobacterium tuberculosis
861
row_72235
false
null
112,205
A1KKJ9
MRQILIAVAVAVTVSILLTPVLIRLFTKQGFGHQIREDGPPSHHTKRGTPSMGGVAILAGIWAGYLGAHLAGLAFDGEGIGASGLLVLGLATALGGVGFIDDLIKIRRSRNLGLNKTAKTVGQITSAVLFGVLVLQFRNAAGLTPGSADLSYVREIATVTLAPVLFVLFCVVIVSAWSNAVNFTDGLDGLAAGTMAMVTAAYVLITFWQYRNACVTAPGLGCYNVRDPLDLALIAAATAGACIGFLWWNAAPAKIFMGDTGSLALGGVIAGLSVTSRTEILAVVLGALFVAEITSVVLQILTFRTTGRRMFRMAPFHHHFELVGWAETTVIIRFWLLTAITCGLGVALFYGEWLAAVGA
Phospho-N-acetylmuramoyl-pentapeptide-transferase (EC 2.7.8.13) (UDP-MurNAc-pentapeptide phosphotransferase)
Mycobacterium bovis (strain BCG / Pasteur 1173P2)
410,289
359
37,713
Cell cycle;Cell division;Cell membrane;Cell shape;Cell wall biogenesis/degradation;Magnesium;Membrane;Metal-binding;Peptidoglycan synthesis;Transferase;Transmembrane;Transmembrane helix
GO:0005886; GO:0008360; GO:0008963; GO:0009252; GO:0046872; GO:0051301; GO:0051992; GO:0071555
Inferred from homology
3
SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_00038}; Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_00038}.
null
TRANSMEM 3..23; /note="Helical"; /evidence="ECO:0000255|HAMAP-Rule:MF_00038"; TRANSMEM 55..75; /note="Helical"; /evidence="ECO:0000255|HAMAP-Rule:MF_00038"; TRANSMEM 80..100; /note="Helical"; /evidence="ECO:0000255|HAMAP-Rule:MF_00038"; TRANSMEM 117..137; /note="Helical"; /evidence="ECO:0000255|HAMAP-Rule:MF_00038"; TRANSMEM 156..176; /note="Helical"; /evidence="ECO:0000255|HAMAP-Rule:MF_00038"; TRANSMEM 187..207; /note="Helical"; /evidence="ECO:0000255|HAMAP-Rule:MF_00038"; TRANSMEM 231..251; /note="Helical"; /evidence="ECO:0000255|HAMAP-Rule:MF_00038"; TRANSMEM 255..275; /note="Helical"; /evidence="ECO:0000255|HAMAP-Rule:MF_00038"; TRANSMEM 280..300; /note="Helical"; /evidence="ECO:0000255|HAMAP-Rule:MF_00038"; TRANSMEM 334..354; /note="Helical"; /evidence="ECO:0000255|HAMAP-Rule:MF_00038"
PF00953;PF10555;
IPR000715;IPR003524;IPR018480;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype), Mycobacterium tuberculosis variant bovis BCG (no rank)
mraY BCG_2173c
false
Mycobacterium tuberculosis
862
row_100670
false
null
213,240
P9WQL5
MRYSDSYHTTGRWQPRASTEGFPMGVSIEVNGLTKSFGSSRIWEDVTLTIPAGEVSVLLGPSGTGKSVFLKSLIGLLRPERGSIIIDGTDIIECSAKELYEIRTLFGVLFQDGALFGSMNLYDNTAFPLREHTKKKESEIRDIVMEKLALVGLGGDEKKFPGEISGGMRKRAGLARALVLDPQIILCDEPDSGLDPVRTAYLSQLIMDINAQIDATILIVTHNINIARTVPDNMGMLFRKHLVMFGPREVLLTSDEPVVRQFLNGRRIGPIGMSEEKDEATMAEEQALLDAGHHAGGVEEIEGVPPQISATPGMPERKAVARRQARVREMLHTLPKKAQAAILDDLEGTHKYAVHEIGQ
Probable ribonucleotide transport ATP-binding protein mkl
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
359
39,394
Acetylation;ATP-binding;Nucleotide-binding;Reference proteome;Transport
GO:0005524; GO:0005886; GO:0009274; GO:0016887; GO:0070508
Evidence at protein level
3
null
null
null
PF00005;
IPR003593;IPR003439;IPR017871;IPR027417;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
mkl Rv0655 MTCI376.21
false
Mycobacterium tuberculosis
863
row_199438
false
null
430,861
P96857
MSPTPRRRATLASLAAELKVSRTTVSNAFNRPDQLSADLRERVLATAKRLGYAGPDPVARSLRTRKAGAVGLVMAEPLTYFFSDPAARDFVAGVAQSCEELGQGLQLVSVGSSRSLADGTAAVLGAGVDGFVVYSVGDDDPYLQVVLQRRLPVVVVDQPKDLSGVSRVGIDDRAAMRELAGYVLGLGHRELGLLTMRLGRDRRQDLVDAERLRSPTFDVQRERIVGVWEAMTAAGVDPDSLTVVESYEHLPTSGGTAAKVALQANPRLTALMCTADILALSAMDYLRAHGIYVPGQMTVTGFDGVPEALSRGLTTVAQPSLHKGHRAGELLLKPPRSGLPVIEVLDTELVRGRTAGPPA
HTH-type transcriptional regulator Rv3575c
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
359
38,210
DNA-binding;Reference proteome;Repressor;Transcription;Transcription regulation
GO:0000976; GO:0003700; GO:0006355
Evidence at protein level
2
null
null
null
PF13377;
IPR000843;IPR046335;IPR010982;IPR028082;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
Rv3575c
false
Mycobacterium tuberculosis
864
row_412623
false
null
26,854
P9WJ93
MTEAIGDEPLGDHVLELQIAEVVDETDEARSLVFAVPDGSDDPEIPPRRLRYAPGQFLTLRVPSERTGSVARCYSLCSSPYTDDALAVTVKRTADGYASNWLCDHAQVGMRIHVLAPSGNFVPTTLDADFLLLAAGSGITPIMSICKSALAEGGGQVTLLYANRDDRSVIFGDALRELAAKYPDRLTVLHWLESLQGLPSASALAKLVAPYTDRPVFICGPGPFMQAARDALAALKVPAQQVHIEVFKSLESDPFAAVKVDDSGDEAPATAVVELDGQTHTVSWPRTAKLLDVLLAAGLDAPFSCREGHCGACACTLRAGKVNMGVNDVLEQQDLDEGLILACQSRPESDSVEVTYDE
3-ketosteroid-9-alpha-monooxygenase, ferredoxin reductase component (3-ketosteroid-9-alpha-hydroxylase, ferredoxin reductase component) (KSH) (Androsta-1,4-diene-3,17-dione 9-alpha-hydroxylase) (EC 1.14.15.30) (Rieske-type oxygenase) (RO)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
358
38,265
2Fe-2S;Cholesterol metabolism;FAD;Flavoprotein;Iron;Iron-sulfur;Lipid degradation;Lipid metabolism;Metal-binding;Oxidoreductase;Reference proteome;Steroid metabolism;Sterol metabolism;Virulence
GO:0001666; GO:0006694; GO:0006707; GO:0008203; GO:0016491; GO:0036200; GO:0046872; GO:0047086; GO:0050660; GO:0051409; GO:0051537; GO:0071949
Evidence at protein level
5
null
null
null
PF00970;PF00111;PF00175;
IPR036010;IPR001041;IPR006058;IPR012675;IPR008333;IPR017927;IPR001709;IPR039261;IPR050415;IPR001433;IPR017938;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
hmp kshB Rv3571
false
Mycobacterium tuberculosis
865
row_23497
false
null
26,990
P9WNW5
MHAVTRPTLREAVARLAPGTGLRDGLERILRGRTGALIVLGHDENVEAICDGGFSLDVRYAATRLRELCKMDGAVVLSTDGSRIVRANVQLVPDPSIPTDESGTRHRSAERAAIQTGYPVISVSHSMNIVTVYVRGERHVLTDSATILSRANQAIATLERYKTRLDEVSRQLSRAEIEDFVTLRDVMTVVQRLELVRRIGLVIDYDVVELGTDGRQLRLQLDELLGGNDTARELIVRDYHANPEPPSTGQINATLDELDALSDGDLLDFTALAKVFGYPTTTEAQDSTLSPRGYRAMAGIPRLQFAHADLLVRAFGTLQGLLAASAGDLQSVDGIGAMWARHVREGLSQLAESTISDQ
DNA integrity scanning protein DisA (Cyclic-di-AMP synthase) (c-di-AMP synthase) (Diadenylate cyclase) (EC 2.7.7.85)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
358
39,031
ATP-binding;DNA damage;DNA repair;DNA-binding;Magnesium;Manganese;Nucleotide-binding;Nucleotidyltransferase;Reference proteome;Transferase
GO:0003677; GO:0004016; GO:0005524; GO:0006281; GO:0106408
Evidence at protein level
5
null
null
null
PF02457;PF10635;
IPR050338;IPR038331;IPR036888;IPR018906;IPR003390;IPR023763;IPR010994;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
disA dacA Rv3586
false
Mycobacterium tuberculosis
866
row_23629
false
null
181,874
L0TDE1
MQLPVMPPVSPMLAKSVTAIPPDASYEPKWDGFRSICFRDGDQVELGSRNERPMTRYFPELVAAIRAELPHRCVIDGEIIIATDHGLDFEALQQRIHPAESRVRMLADRTPASFIAFDLLALGDDDYTGRPFSERRAALVDAVTGSGADADLSIHVTPATTDMATAQRWFSEFEGAGLDGVIAKPPHITYQPDKRVMFKIKHLRTADCVVAGYRVHKSGSDAIGSLLLGLYQEDGQLASVGVIGAFPMAERRRLLTELQPLVTSFDDHPWNWAAHVAGQRTPRKNEFSRWNVGKDLSFVPLRPERVVEVRYDRMEGARFRHTAQFNRWRPDRDPRSCSYAQLERPLTVSLSDIVPGLR
DNA ligase C (EC 6.5.1.1) (Polydeoxyribonucleotide synthase [ATP])
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
358
40,160
ATP-binding;Ligase;Nucleotide-binding;Reference proteome
GO:0003910; GO:0005524; GO:0006281; GO:0006310
Evidence at protein level
3
null
null
null
PF04679;PF01068;
IPR044119;IPR050191;IPR012309;IPR012310;IPR012340;IPR044117;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
ligC Rv3731
false
Mycobacterium tuberculosis
867
row_168911
false
null
431,779
P9WKT1
MGNVAGETRANVIPLHTNRSRVAARRRAGQRAESRQHPSLLSDPNDRASAEQIAAVVREIDEHRRAAGATTSSTEATPNDLAQLVAAVAGFLRQRLTGDYSVDEFGFDPHFNSAIVRPLLRFFFKSWFRVEVSGVENIPRDGAALVVANHAGVLPFDGLMLSVAVHDEHPAHRDLRLLAADMVFDLPVIGEAARKAGHTMACTTDAHRLLASGELTAVFPEGYKGLGKRFEDRYRLQRFGRGGFVSAALRTKAPIVPCSIIGSEEIYPMLTDVKLLARLFGLPYFPITPLFPLAGPVGLVPLPSKWRIAFGEPICTADYASTDADDPMVTFELTDQVRETIQQTLYRLLAGRRNIFFG
Uncharacterized protein Rv0502
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
358
39,288
Reference proteome
GO:0005886; GO:0016020; GO:0016746
Evidence at protein level
2
null
null
null
PF01553;
IPR016676;IPR002123;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
Rv0502 MTCY20G9.29
false
Mycobacterium tuberculosis
868
row_413534
false
null
546,614
P9WJZ2
MRARFGDRAPWLVETTLLRRRAAGKLGELCPNVGVSQWLFTDEALQQATAAPVARHRARRLAGRVVHDATCSIGTELAALRELAVRAVGSDIDPVRLAMARHNLAALGMEADLCRADVLHPVTRDAVVVIDPARRSNGRRRFHLADYQPGLGPLLDRYRGRDVVVKCAPGIDFEEVGRLGFEGEIEVISYRGGVREACLWSAGLAGSGIRRRASILDSGEQIGDDEPDDCGVRPAGKWIVDPDGAVVRAGLVRNYGARHGLWQLDPQIAYLSGDRLPPALRGFEVLEQLAFDERRLRQVLSALDCGAAEILVRGVAIDPDALRRRLRLRGSRPLAVVITRIGAGSLSHVTAYVCRPSR
Uncharacterized S-adenosylmethionine-dependent methyltransferase MT3122 (EC 2.1.1.-)
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
83,331
358
39,082
Methyltransferase;Reference proteome;S-adenosyl-L-methionine;Transferase
GO:0008168; GO:0032259
Inferred from homology
1
null
null
null
PF18096;
IPR029063;IPR041497;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
MT3122
false
Mycobacterium tuberculosis
869
row_526706
false
null
112,201
A1KKI2
MYPLVRRLLFLIPPEHAHKLVFAVLRGVAAVAPVCRLLRRLLGPTDPVLASTVFGVRFPAPLGLAAGFDKDGTALSSWGAMGFGYAEIGTVTAHPQPGNPAPRLFRLADDRALLNRMGFNNHGARALAIRLARHRPEIPIGVNIGKTKKTPAGDAVNDYRASARMVGPLASYLVVNVSSPNTPGLRDLQAVESLRPILSAVRAETSTPVLVKIAPDLSDSDLDDIADLAVELDLAGIVATNTTVSRDGLTTPGVDRLGPGGISGPPLAQRAVQVLRRLYDRVGDRLALISVGGIETADDAWERITAGASLLQGYTGFIYGGERWAKDIHEGIARRLHDGGFGSLHEAVGSARRRQPS
Dihydroorotate dehydrogenase (quinone) (EC 1.3.5.2) (DHOdehase) (DHOD) (DHODase) (Dihydroorotate oxidase)
Mycobacterium bovis (strain BCG / Pasteur 1173P2)
410,289
357
37,946
Cell membrane;Flavoprotein;FMN;Membrane;Oxidoreductase;Pyrimidine biosynthesis
GO:0005737; GO:0005886; GO:0006207; GO:0044205; GO:0106430
Inferred from homology
3
SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_00225}; Peripheral membrane protein {ECO:0000255|HAMAP-Rule:MF_00225}.
null
null
PF01180;
IPR013785;IPR050074;IPR005719;IPR005720;IPR001295;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype), Mycobacterium tuberculosis variant bovis BCG (no rank)
pyrD BCG_2156
false
Mycobacterium tuberculosis
870
row_100666
false
null
112,234
A1KM16
MSTRRDLPQSPYLAAVTGRKPSRVPVWFMRQAGRSLPEYRALRERYSMLAACFEPDVACEITLQPIRRYDVDAAILFSDIVVPLRAAGVDLDIVADVGPVIADPVRTAADVAAMKPLDPQAIQPVLVAASLLVAELGDVPLIGFAGAPFTLASYLVEGGPSRHHAHVKAMMLAEPASWHALMAKLTDLTIAFLVGQIDAGVDAIQVFDSWAGALSPIDYRQYVLPHSARVFAALGEHGVPMTHFGVGTAELLGAMSEAVTAGERPGRGAVVGVDWRTPLTDAAARVVPGTALQGNLDPAVVLAGWPAVERAARAVVDDGRRAVDAGAAGHIFNLGHGVLPESDPAVLADLVSLVHSL
Uroporphyrinogen decarboxylase (UPD) (URO-D) (EC 4.1.1.37)
Mycobacterium bovis (strain BCG / Pasteur 1173P2)
410,289
357
37,606
Cytoplasm;Decarboxylase;Lyase;Porphyrin biosynthesis
GO:0004853; GO:0005829; GO:0006782
Inferred from homology
3
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00218}.
null
null
PF01208;
IPR038071;IPR006361;IPR000257;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype), Mycobacterium tuberculosis variant bovis BCG (no rank)
hemE BCG_2691c
false
Mycobacterium tuberculosis
871
row_100699
false
null
321,064
A1KI87
MTQPVQTIDVLLAEHAELELALADPALHSNPAEARRVGRRFARLAPIVATHRKLTSARDDLETARELVASDESFAAEVAALEARVGELDAQLTDMLAPRDPHDADDIVLEVKSGEGGEESALFAADLARMYIRYAERHGWAVTVLDETTSDLGGYKDATLAIASKADTPDGVWSRMKFEGGVHRVQRVPVTESQGRVHTSAAGVLVYPEPEEVGQVQIDESDLRIDVFRSSGKGGQGVNTTDSAVRITHLPTGIVVTCQNERSQLQNKTRALQVLAARLQAMAEEQALADASADRASQIRTVDRSERIRTYNFPENRITDHRIGYKSHNLDQVLDGDLDALFDALSAADKQSRLRQS
Peptide chain release factor 1 (RF-1)
Mycobacterium bovis (strain BCG / Pasteur 1173P2)
410,289
357
39,036
Cytoplasm;Methylation;Protein biosynthesis
GO:0005737; GO:0016149
Inferred from homology
2
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00093}.
null
null
PF03462;PF00472;
IPR005139;IPR000352;IPR045853;IPR050057;IPR004373;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype), Mycobacterium tuberculosis variant bovis BCG (no rank)
prfA BCG_1359
false
Mycobacterium tuberculosis
872
row_304436
false
null
544,784
P65094
MVTVARRPVCPVTLTPGDPALASVRDLVDAWSAHDALAELVTMFGGAFPQTDHLEARLASLDKFSTAWDYRARARAARALHGEPVRCQDSGGGARWLIPRLDLPAKKRDAIVGLAQQLGLTLESTPQGTTFDHVLVIGTGRHSNLIRARWARELAKGRQVGHIVLAAASRRLLPSEDDAVAVCAPGARTEFELLAAAARDAFGLDVHPAVRYVRQRDDNPHRDSMVWRFAADTNDLGVPITLLEAPSPEPDSSRATSADTFTFTAHTLGMQDSTCLLVTGQPFVPYQNFDALRTLALPFGIQVETVGFGIDRYDGLGELDQQHPAKLLQEVRSTIRAARALLERIEAGERMATDPRR
Uncharacterized protein Mb3814
Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
233,413
357
38,931
Reference proteome
null
Predicted
1
null
null
null
null
null
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype)
BQ2027_MB3814
false
Mycobacterium tuberculosis
873
row_525027
false
null
181,644
I6YC03
MSQVHRILNCRGTRIHAVADSPPDQQGPLVVLLHGFPESWYSWRHQIPALAGAGYRVVAIDQRGYGRSSKYRVQKAYRIKELVGDVVGVLDSYGAEQAFVVGHDWGAPVAWTFAWLHPDRCAGVVGISVPFAGRGVIGLPGSPFGERRPSDYHLELAGPGRVWYQDYFAVQDGIITEIEEDLRGWLLGLTYTVSGEGMMAATKAAVDAGVDLESMDPIDVIRAGPLCMAEGARLKDAFVYPETMPAWFTEADLDFYTGEFERSGFGGPLSFYHNIDNDWHDLADQQGKPLTPPALFIGGQYDVGTIWGAQAIERAHEVMPNYRGTHMIADVGHWIQQEAPEETNRLLLDFLGGLRP
Epoxide hydrolase B (EHB) (EC 3.3.2.10) (Epoxide hydrolase EphB)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
356
39,297
Detoxification;Hydrolase;Reference proteome
GO:0004301; GO:0009636; GO:0016787; GO:0042803
Evidence at protein level
3
null
null
null
PF00561;
IPR000073;IPR029058;IPR000639;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
ephB Rv1938
false
Mycobacterium tuberculosis
874
row_168690
false
null
209,151
P71847
MRLRTPLTELIGIEHPVVQTGMGWVAGARLVSATANAGGLGILASATMTLDELAAAITKVKAVTDKPFGVNIRADAADAGDRVELMIREGVRVASFALAPKQQLIARLKEAGAVVIPSIGAAKHARKVAAWGADAMIVQGGEGGGHTGPVATTLLLPSVLDAVAGTGIPVIAAGGFFDGRGLAAALCYGAAGVAMGTRFLLTSDSTVPDAVKRRYLQAGLDGTVVTTRVDGMPHRVLRTELVEKLESGSRARGFAAALRNAGKFRRMSQMTWRSMIRDGLTMRHGKELTWSQVLMAANTPMLLKAGLVDGNTEAGVLASGQVAGILDDLPSCKELIESIVLDAITHLQTASALVE
(3aS,4S,5R,7aS)-5-hydroxy-7a-methyl-1-oxo-octahydro-1H-indene-4-carboxyl-CoA dehydrogenase (5OH-HIC-CoA dehydrogenase) (EC 1.3.1.-)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
355
36,831
Cholesterol metabolism;Flavoprotein;FMN;Lipid metabolism;NAD;Nucleotide-binding;Oxidoreductase;Reference proteome;Steroid metabolism;Sterol metabolism
GO:0000166; GO:0005886; GO:0006707; GO:0018580
Evidence at protein level
3
null
null
null
PF03060;
IPR013785;IPR004136;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
ipdC Rv3553
false
Mycobacterium tuberculosis
875
row_195551
false
null
431,815
P9WL89
MSASLLVRTACGGRAVAQRLRTVLWPITQTSVVAGLAWYLTHDVFNHPQAFFAPISAVVCMSATNVLRARRAQQMIVGVALGIVLGAGVHALLGSGPIAMGVVVFIALSVAVLCARGLVAQGLMFINQAAVSAVLVLVFASNGSVVFERLFDALVGGGLAIVFSILLFPPDPVVMLCSARADVLAAVRDILAELVNTVSDPTSAPPDWPMAAADRLHQQLNGLIEVRANAAMVARRAPRRWGVRSTVRDLDQQAVYLALLVSSVLHLARTIAGPGGDKLPTPVHAVLTDLAAGTGLADADPTAANEHAAAARATASTLQSAACGSNEVVRADIVQACVTDLQRVIERPGPSGMSA
Putative arylamide transporter
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
355
36,790
Cell membrane;Membrane;Reference proteome;Transmembrane;Transmembrane helix;Transport
GO:0005886
Evidence at protein level
2
SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000255}.
null
TRANSMEM 22..42; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 44..64; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 71..91; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 92..112; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 119..139; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 150..170; /note="Helical"; /evidence="ECO:0000255"
PF13515;
IPR049453;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
Rv2571c MTCY227.30
false
Mycobacterium tuberculosis
876
row_413570
false
null
212,556
P9WHS8
MLDLRGDPIELTAALIDIPSESRKEARIADEVEAALRAQASGFEIIRNGNAVLARTKLNRSSRVLLAGHLDTVPVAGNLPSRRENDQLHGCGAADMKSGDAVFLHLAATLAEPTHDLTLVFYDCEEIDSAANGLGRIQRELPDWLSADVAILGEPTAGCIEAGCQGTLRVVLSVTGTRAHSARSWLGDNAIHKLGAVLDRLAVYRARSVDIDGCTYREGLSAVRVAGGVAGNVIPDAASVTINYRFAPDRSVAAALQHVHDVFDGLDVQIEQTDAAAGALPGLSEPAAKALVEAAGGQVRAKYGWTDVSRFAALGIPAVNYGPGDPNLAHCRDERVPVGNITAAVDLLRRYLGG
Putative succinyl-diaminopimelate desuccinylase DapE (SDAP desuccinylase) (EC 3.5.1.18)
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
83,331
354
37,273
Amino-acid biosynthesis;Cobalt;Diaminopimelate biosynthesis;Hydrolase;Lysine biosynthesis;Metal-binding;Reference proteome;Zinc
GO:0006526; GO:0008777; GO:0009014; GO:0009089; GO:0019877; GO:0046872
Inferred from homology
3
null
null
null
PF07687;PF01546;
IPR001261;IPR036264;IPR002933;IPR011650;IPR050072;IPR010174;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
dapE MT1240
false
Mycobacterium tuberculosis
877
row_198764
false
null
5,743
O33194
MKSIAQEHDCLLIDLDGTVFCGRQPTGGAVQSLSQVRSRKLFVTNNASRSADEVAAHLCELGFTATGEDVVTSAQSAAHLLAGQLAPGARVLIVGTEALANEVAAVGLRPVRRFEDRPDAVVQGLSMTTGWSDLAEAALAIRAGALWVAANVDPTLPTERGLLPGNGSMVAALRTATGMDPRVAGKPAPALMTEAVARGDFRAALVVGDRLDTDIEGANAAGLPSLMVLTGVNSAWDAVYAEPVRRPTYIGHDLRSLHQDSKLLAVAPQPGWQIDVGGGAVTVCANGDVDDLEFIDDGLSIVRAVASAVWEARAADLHQRPLRIEAGDERARAALQRWSLMRSDHPVTSVGTQ
D-glycerol 3-phosphate phosphatase (D,L-glycerol 3-phosphate phosphatase) (G3P phosphatase)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
353
37,011
3D-structure;Glycerol metabolism;Hydrolase;Magnesium;Metal-binding;Reference proteome
GO:0000121; GO:0000287; GO:0005737; GO:0006071; GO:0016791; GO:0030145; GO:0042803; GO:0046475; GO:0050897
Evidence at protein level
5
null
null
null
PF18407;PF13344;PF13242;
IPR041065;IPR036412;IPR006357;IPR023214;
4I9G;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
Rv1692
false
Mycobacterium tuberculosis
878
row_4677
false
null
26,930
P9WML5
MTARLRPELAGLPVYVPGKTVPGAIKLASNETVFGPLPSVRAAIDRATDTVNRYPDNGCVQLKAALARHLGPDFAPEHVAVGCGSVSLCQQLVQVTASVGDEVVFGWRSFELYPPQVRVAGAIPIQVPLTDHTFDLYAMLATVTDRTRLIFVCNPNNPTSTVVGPDALARFVEAVPAHILIAIDEAYVEYIRDGMRPDSLGLVRAHNNVVVLRTFSKAYGLAGLRIGYAIGHPDVITALDKVYVPFTVSSIGQAAAIASLDAADELLARTDTVVAERARVSAELRAAGFTLPPSQANFVWLPLGSRTQDFVEQAADARIVVRPYGTDGVRVTVAAPEENDAFLRFARRWRSDQ
Aromatic amino acid aminotransferase (ArAT) (EC 2.6.1.57) (Phenylalanine aminotransferase)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
353
38,040
3D-structure;Aminotransferase;Pyridoxal phosphate;Reference proteome;Transferase
GO:0000105; GO:0004400; GO:0030170; GO:0080130
Evidence at protein level
5
null
null
null
PF00155;
IPR001917;IPR004839;IPR024892;IPR005861;IPR050106;IPR015424;IPR015421;IPR015422;
4R2N;4R5Z;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
pat hisC2 Rv3772 MTCY13D12.06
false
Mycobacterium tuberculosis
879
row_23571
false
null
27,020
P9WPF3
MSVIAGVFGALPPHRYSQSEITDSFVEFPGLKEHEEIIRRLHAAAKVNGRHLVLPLQQYPSLTDFGDANEIFIEKAVDLGVEALLGALDDANLRPSDIDMIATATVTGVAVPSLDARIAGRLGLRPDVRRMPLFGLGCVAGAAGVARLRDYLRGAPDDVAVLVSVELCSLTYPAVKPTVSSLVGTALFGDGAAAVVAVGDRRAEQVRAGGPDILDSRSSLYPDSLHIMGWDVGSHGLRLRLSPDLTNLIERYLANDVTTFLDAHRLTKDDIGAWVSHPGGPKVIDAVATSLALPPEALELTWRSLGEIGNLSSASILHILRDTIEKRPPSGSAGLMLAMGPGFCTELVLLRWR
Methyl-branched alkylpyrone synthesis polyketide synthase-like Pks11 (EC 2.3.1.-) (Chalcone synthase-like protein) (CHS-like) (Methyl-branched alkylpyrone synthesis polyketide synthase type III Pks11)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
353
37,639
3D-structure;Acyltransferase;Fatty acid metabolism;Lipid metabolism;Reference proteome;Transferase
GO:0006633; GO:0008610; GO:0009715; GO:0016747; GO:0030639; GO:0034081; GO:0071770
Evidence at protein level
5
null
null
null
PF02797;PF00195;
IPR012328;IPR001099;IPR011141;IPR016039;
4JAO;4JAP;4JAQ;4JAR;4JAT;4JD3;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
pks11 Rv1665
false
Mycobacterium tuberculosis
880
row_23659
false
null
81,911
P9WPF5
MSVIAGVFGALPPYRYSQRELTDSFVSIPDFEGYEDIVRQLHASAKVNSRHLVLPLEKYPKLTDFGEANKIFIEKAVDLGVQALAGALDESGLRPEDLDVLITATVTGLAVPSLDARIAGRLGLRADVRRVPLFGLGCVAGAAGVARLHDYLRGAPDGVAALVSVELCSLTYPGYKPTLPGLVGSALFADGAAAVVAAGVKRAQDIGADGPDILDSRSHLYPDSLRTMGYDVGSAGFELVLSRDLAAVVEQYLGNDVTTFLASHGLSTTDVGAWVTHPGGPKIINAITETLDLSPQALELTWRSLGEIGNLSSASVLHVLRDTIAKPPPSGSPGLMIAMGPGFCSELVLLRWH
Polyketide synthase-like Pks10 (EC 2.3.1.-) (Chalcone synthase-like protein) (CHS-like) (Polyketide synthase type III Pks10)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
353
37,146
Acyltransferase;Fatty acid metabolism;Lipid metabolism;Reference proteome;Transferase
GO:0005886; GO:0006633; GO:0008610; GO:0016747; GO:0030639; GO:0034081; GO:0071770
Evidence at protein level
4
null
null
null
PF02797;PF00195;
IPR012328;IPR001099;IPR011141;IPR016039;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
pks10 Rv1660
false
Mycobacterium tuberculosis
881
row_72351
false
null
185,401
O53532
MSGALETTEEFGNRFVAAIDSAGLAILVSVGHQTGLLDTMAGLPPATSMEIAEAAGLEERYVREWLGGMTTGQIVEYDAGSSTYSLPAHRAGMLTRAAGPDNLAVIAQFVSLLGEVEQKVIRCFREGGGVPYSEYPRFHKLMAEMSGMVFDAALIDVVLPLVDGLPDRLRSGADVADFGCGSGRAVKLMAQAFGASRFTGIDFSDEAVAAGTEEAARLGLANATFERHDLAELDKVGAYDVITVFDAIHDQAQPARVLQNIYRALRPGGVLLMVDIKASSQLEDNVGVPLSTYLYTTSLMHCMTVSLALDGAGLGTVWGRQLATSMLADAGFTDVTVAEIESDVLNNYYIARK
S-adenosylmethionine-dependent methyltransferase Rv2258c (EC 2.1.1.-)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
353
37,514
3D-structure;Methyltransferase;Reference proteome;S-adenosyl-L-methionine;Transferase
GO:0005886; GO:0008168; GO:0009274; GO:0032259; GO:0071456
Evidence at protein level
3
null
null
null
PF21320;PF13847;
IPR025714;IPR048711;IPR053173;IPR029063;
5F8C;5F8E;5F8F;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
Rv2258c
false
Mycobacterium tuberculosis
882
row_172360
false
null
6,630
O53605
MITYGSGDLLRADTEALVNTVNCVGVMGKGIALQFKRRYPEMFTAYEKACKRGEVTIGKMFVVDTGQLDGPKHIINFPTKKHWRAPSKLAYIDAGLIDLIRVIRELNIASVAVPPLGVGNGGLDWEDVEQRLVSAFQQLPDVDAVIYPPSGGSRAIEGVEGLRMTWGRAVILEAMRRYLQQRRAMEPWEDPAGISHLEIQKLMYFANEADPDLALDFTPGRYGPYSERVRHLLQGMEGAFTVGLGDGTARVLANQPISLTTKGTDAITDYLATDAAADRVSAAVDTVLRVIEGFEGPYGVELLASTHWVATREGAKEPATAAAAVRKWTKRKGRIYSDDRIGVALDRILMTA
DNA ADP-ribosyl glycohydrolase (DarG) (EC 3.2.2.-) (Antitoxin DarG)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
352
38,563
3D-structure;Hydrolase;Reference proteome;Toxin-antitoxin system
GO:0005829; GO:0006974; GO:0042278; GO:0047407
Evidence at protein level
5
null
null
null
PF01661;
IPR050892;IPR002589;IPR043472;
5M3I;7YK3;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
darG Rv0060
false
Mycobacterium tuberculosis
883
row_5464
false
null
69,177
O53507
MAGAITDQLRRYLHGRRRAAAHMGSDYDGLIADLEDFVLGGGKRLRPLFAYWGWHAVASREPDPDVLLLFSALELLHAWALVHDDLIDRSATRRGRPTAQLRYAALHRDRDWRGSPDQFGMSAAILLGDLAQVWADDIVSKVCQSALAPDAQRRVHRVWADIRNEVLGGQYLDIVAEASAAESIESAMNVATLKTACYTVSRPLQLGTAAAADRSDVAAIFEHFGADLGVAFQLRDDVLGVFGDPAVTGKPSGDDLKSGKRTVLVAEAVELADRSDPLAAKLLRTSIGTRLTDAQVRELRTVIEAVGARAAAESRIAALTQRALATLASAPINATAKAGLSELAMMAANRSA
(2E,6E)-farnesyl diphosphate synthase (E,E-FPP synthase) (FPP synthase) (EC 2.5.1.10) (Dimethylallyltranstransferase) (EC 2.5.1.1) (Geranyl diphosphate synthase) (GPP synthase)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
352
37,781
3D-structure;Lipid biosynthesis;Lipid metabolism;Magnesium;Metal-binding;Reference proteome;Transferase
GO:0004161; GO:0004337; GO:0004659; GO:0008299; GO:0033384; GO:0046872
Evidence at protein level
4
null
null
null
PF00348;
IPR054885;IPR008949;IPR000092;IPR033749;
8F8F;8F8K;8F8L;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
idsA2 Rv2173
false
Mycobacterium tuberculosis
884
row_60178
false
null
112,183
A1KJ69
MQNRQVANATKVAVAGASGYAGGEILRLLLGHPAYADGRLRIGALTAATSAGSTLGEHHPHLTPLAHRVVEPTEAAVLGGHDAVFLALPHGHSAVLAQQLSPETLIIDCGADFRLTDAAVWERFYGSSHAGSWPYGLPELPGARDQLRGTRRIAVPGCYPTAALLALFPALAADLIEPAVTVVAVSGTSGAGRAATTDLLGAEVIGSARAYNIAGVHRHTPEIAQGLRAVTDRDVSVSFTPVLIPASRGILATCTARTRSPLSQLRAAYEKAYHAEPFIYLMPEGQLPRTGAVIGSNAAHIAVAVDEDAQTFVAIAAIDNLVKGTAGAAVQSMNLALGWPETDGLSVVGVAP
N-acetyl-gamma-glutamyl-phosphate reductase (AGPR) (EC 1.2.1.38) (N-acetyl-glutamate semialdehyde dehydrogenase) (NAGSA dehydrogenase)
Mycobacterium bovis (strain BCG / Pasteur 1173P2)
410,289
352
36,304
Amino-acid biosynthesis;Arginine biosynthesis;Cytoplasm;NADP;Oxidoreductase
GO:0003942; GO:0005737; GO:0006526; GO:0051287; GO:0070401
Inferred from homology
3
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00150}.
null
null
PF01118;PF22698;
IPR023013;IPR000706;IPR036291;IPR050085;IPR000534;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype), Mycobacterium tuberculosis variant bovis BCG (no rank)
argC BCG_1691
false
Mycobacterium tuberculosis
885
row_100648
false
null
409,970
P0A5S1
MTSRETRAADAAGARQADAQVRSSIDVPPDLVVGLLGSADENLRALERTLSADLHVRGNAVTLCGEPADVALAERVISELIAIVASGQSLTPEVVRHSVAMLVGTGNESPAEVLTLDILSRRGKTIRPKTLNQKRYVDAIDANTIVFGIGPAGTGKTYLAMAKAVHALQTKQVTRIILTRPAVEAGERLGFLPGTLSEKIDPYLRPLYDALYDMMDPELIPKLMSAGVIEVAPLAYMRGRTLNDAFIVLDEAQNTTAEQMKMFLTRLGFGSKVVVTGDVTQIDLPGGARSGLRAAVDILEDIDDIHIAELTSVDVVRHRLVSEIVDAYARYEEPGSGLNRAARRASGARGRR
PhoH-like protein
Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
233,413
352
37,799
ATP-binding;Cytoplasm;Nucleotide-binding;Reference proteome
GO:0003723; GO:0005524; GO:0005829
Inferred from homology
2
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
null
null
PF02562;
IPR004087;IPR036612;IPR027417;IPR003714;IPR051451;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype)
BQ2027_MB2389C
false
Mycobacterium tuberculosis
886
row_392426
false
null
431,932
P9WMT2
MLGDTEVLANLRVLQTELTGAGILEPLLSADGTTDVLVTAPDSVWVDDGNGLRRSQIRFADESAVRRLAQRLALAAGRRLDDAQPWVDGQLTGIGVGGFAVRLHAVLPPVATQGTCLSLRVLRPATQDLAALAAAGAIDPAAAALVADIVTARLAFLVCGGTGAGKTTLLAAMLGAVSPDERIVCVEDAAELAPRHPHLVKLVARRANVEGIGEVTVRQLVRQALRMRPDRIVVGEVRGAEVVDLLAALNTGHEGGAGTVHANNPGEVPARMEALGALGGLDRAALHSQLAAAVQVLLHVARDRAGRRRLAEIAVLRQAEGRVQAVTVWHADRGMSDDAAALHDLLRSRASA
Putative conjugal transfer protein MT3759
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
83,331
352
36,691
ATP-binding;Conjugation;Cytoplasm;Nucleotide-binding;Plasmid;Reference proteome;Transport
GO:0005524; GO:0005737; GO:0016887
Inferred from homology
2
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
null
null
PF00437;
IPR027417;IPR001482;IPR050921;IPR022399;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
MT3759
false
Mycobacterium tuberculosis
887
row_413687
false
null
81,963
P9WQM1
MTYAIVVADATKRYGDFVALDHVDFVVPTGSLTALLGPSGSGKSTLLRTIAGLDQPDTGTITINGRDVTRVPPQRRGIGFVFQHYAAFKHLTVRDNVAFGLKIRKRPKAEIKAKVDNLLQVVGLSGFQSRYPNQLSGGQRQRMALARALAVDPEVLLLDEPFGALDAKVREELRAWLRRLHDEVHVTTVLVTHDQAEALDVADRIAVLHKGRIEQVGSPTDVYDAPANAFVMSFLGAVSTLNGSLVRPHDIRVGRTPNMAVAAADGTAGSTGVLRAVVDRVVVLGFEVRVELTSAATGGAFTAQITRGDAEALALREGDTVYVRATRVPPIAGGVSGVDDAGVERVKVTST
Sulfate/thiosulfate import ATP-binding protein CysA (EC 7.3.2.3) (Sulfate-transporting ATPase)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
351
37,444
Acetylation;ATP-binding;Cell membrane;Membrane;Nucleotide-binding;Reference proteome;Sulfate transport;Translocase;Transport
GO:0005524; GO:0005886; GO:0015419; GO:0016887; GO:0043190; GO:0102025; GO:1902358
Evidence at protein level
4
SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01701}; Peripheral membrane protein {ECO:0000255|HAMAP-Rule:MF_01701}.
null
null
PF00005;PF12857;
IPR003593;IPR050093;IPR003439;IPR017871;IPR008995;IPR027417;IPR005666;IPR024765;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
cysA Rv2397c MTCY253.24
false
Mycobacterium tuberculosis
888
row_72395
false
null
185,186
O50410
MGGVLTLDAAFLGSVPADLGKALLERARADCGPVLHRAIESMREPLATMAGYHLGWWNADRSTAAGSSGKYFRAALVYAAAAACGGDVGDATPVSAAVELVHNFTLLHDDVMDGDATRRGRPTVWSVWGVGVAILLGDALHATAVRILTGLTDECVAVRAIRRLQMSCLDLCIGQFEDCLLEGQPEVTVDDYLRMAAGKTAALTGCCCALGALVANADDATIAALERFGHELGLAFQCVDDLIGIWGDPGVTGKPVGNDLARRKATLPVVAALNSRSEAATELAALYQAPAAMTASDVERATALVKVAGGGHVAQRCADERIQAAIAALPDAVRSPDLIALSQLICRREC
Geranylgeranyl diphosphate synthase (GGPP synthase) (GGPS) (EC 2.5.1.29)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
350
36,432
Lipid biosynthesis;Lipid metabolism;Magnesium;Metal-binding;Reference proteome;Transferase
GO:0004311; GO:0004659; GO:0005829; GO:0008299; GO:0033386; GO:0046872
Evidence at protein level
3
null
null
null
PF00348;
IPR008949;IPR000092;IPR033749;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
idsB Rv3383c
false
Mycobacterium tuberculosis
889
row_172150
false
null
431,787
P9WKX6
MLTDPGLRDELDRVAAAVGVRVVHLGGRHPVSRKTWSAAAAVVLDHAAADRCGRLALPRRTHVSVLTGTEAATATWAAAITVGAQHVLRMPEQEGELVRELAEAAESARDDGICGAVVAVIGGRGGAGASLFAVALAQAAADALLVDLDPWAGGIDLLVGGETAPGLRWPDLALQGGRLNWSAVRAALPRPRGISVLSGTRRGYELDAGPVDAVIDAGRRGGVTVVCDLPRRLTDATQAALDAADLVVLVSPCDVRACAAAATMAPVLTAINPNLGLVVRGPSPGGLRAAEVADVAGVPLLASMRAQPRLAEQLEHGGLRLRRRSVLASAARRVLGVLPRAGSGRHGRAA
Uncharacterized protein MT3760
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
83,331
350
35,807
Reference proteome
GO:0005524; GO:0005829; GO:0009898; GO:0016887; GO:0051782
Inferred from homology
2
null
null
null
null
IPR027417;IPR050625;IPR022521;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
MT3760
false
Mycobacterium tuberculosis
890
row_413542
false
null
27,033
P9WPQ7
MTQAATRPTNDAGQDGGNNSDILVVARQQVLQRGEGLNQDQVLAVLQLPDDRLEELLALAHEVRMRWCGPEVEVEGIISLKTGGCPEDCHFCSQSGLFASPVRSAWLDIPSLVEAAKQTAKSGATEFCIVAAVRGPDERLMAQVAAGIEAIRNEVEINIACSLGMLTAEQVDQLAARGVHRYNHNLETARSFFANVVTTHTWEERWQTLSMVRDAGMEVCCGGILGMGETLQQRAEFAAELAELGPDEVPLNFLNPRPGTPFADLEVMPVGDALKAVAAFRLALPRTMLRFAGGREITLGDLGAKRGILGGINAVIVGNYLTTLGRPAEADLELLDELQMPLKALNASL
Biotin synthase (EC 2.8.1.6)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
349
37,550
2Fe-2S;4Fe-4S;Acetylation;Biotin biosynthesis;Iron;Iron-sulfur;Metal-binding;Reference proteome;S-adenosyl-L-methionine;Transferase
GO:0004076; GO:0005506; GO:0005886; GO:0009102; GO:0009274; GO:0051537; GO:0051539
Evidence at protein level
5
null
null
null
PF06968;PF04055;
IPR013785;IPR010722;IPR002684;IPR024177;IPR006638;IPR007197;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
bioB Rv1589 MTCY336.15c
false
Mycobacterium tuberculosis
891
row_23672
false
null
212,700
P9WJK1
MTVLNRTDTLVDELTADITNTPLGYGGVDGDERWAAEIRRLAHLRGATVLAHNYQLPAIQDVADHVGDSLALSRVAAEAPEDTIVFCGVHFMAETAKILSPHKTVLIPDQRAGCSLADSITPDELRAWKDEHPGAVVVSYVNTTAAVKALTDICCTSSNAVDVVASIDPDREVLFCPDQFLGAHVRRVTGRKNLHVWAGECHVHAGINGDELADQARAHPDAELFVHPECGCATSALYLAGEGAFPAERVKILSTGGMLEAAHTTRARQVLVATEVGMLHQLRRAAPEVDFRAVNDRASCKYMKMITPAALLRCLVEGADEVHVDPGIAASGRRSVQRMIEIGHPGGGE
Quinolinate synthase (EC 2.5.1.72)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
349
37,408
4Fe-4S;Cytoplasm;Iron;Iron-sulfur;Metal-binding;Pyridine nucleotide biosynthesis;Reference proteome;Transferase
GO:0005829; GO:0008987; GO:0009274; GO:0034628; GO:0046872; GO:0051539
Evidence at protein level
3
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00568}.
null
null
PF02445;
IPR003473;IPR036094;IPR023066;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
nadA Rv1594 MTCY336.10c
false
Mycobacterium tuberculosis
892
row_198907
false
null
431,156
P9WG15
MLFAALRDVQWRKRRLVIAIVSTGLVFAMTLVLTGLVNGFRVEAERTVDSMGVDAFVVKAGAAGPFLGSTPFAQIDLPQVARAPGVLAAAPLATAPSTIRQGTSARNVTAFGAPEHGPGMPRVSDGRAPSTPDEVAVSSTLGRNLGDDLQVGARTLRIVGIVPESTALAKIPNIFLTTEGLQQLAYNGQPTISSIGIDGMPRQLPDGYQTVNRADAVSDLMRPLKVAVDAITVVAVLLWIVAALIVGSVVYLSALERLRDFAVFKAIGVPTRSILAGLALQAVVVALLAAVVGGILSLLLAPLFPMTVVVPLSAFVALPAIATVIGLLASVAGLRRVVAIDPALAFGGP
Uncharacterized ABC transporter permease Rv2563
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
349
36,025
Cell membrane;Membrane;Reference proteome;Transmembrane;Transmembrane helix;Transport
GO:0005576; GO:0005886
Evidence at protein level
2
SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
null
TRANSMEM 17..37; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 230..250; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 284..304; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 308..328; /note="Helical"; /evidence="ECO:0000255"
PF02687;PF12704;
IPR051125;IPR003838;IPR025857;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
Rv2563 MTCY9C4.05c
false
Mycobacterium tuberculosis
893
row_412915
false
null
431,157
P9WG16
MLFAALRDMQWRKRRLVITIISTGLIFGMTLVLTGLANGFRVEARHTVDSMGVDVFVVRSGAAGPFLGSIPFPDVDLARVAAEPGVMAAAPLGSVGTIMKEGTSTRNVTVFGAPEHGPGMPRVSEGRSPSKPDEVAASSTMGRHLGDTVEVGARRLRVVGIVPNSTALAKIPNVFLTTEGLQKLAYNGQPNITSIGIIGMPRQLPEGYQTFDRVGAVNDLVRPLKVAVNSISIVAVLLWIVAVLIVGSVVYLSALERLRDFAVFKAIGTPTRSIMAGLALQALVIALLAAVVGVVLAQVLAPLFPMIVAVPVGAYLALPVAAIVIGLFASVAGLKRVVTVDPAQAFGGP
Uncharacterized ABC transporter permease MT0078
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
83,331
349
36,410
Cell membrane;Membrane;Reference proteome;Transmembrane;Transmembrane helix;Transport
GO:0005886
Inferred from homology
2
SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
null
TRANSMEM 16..36; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 231..251; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 284..304; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 307..327; /note="Helical"; /evidence="ECO:0000255"
PF02687;PF12704;
IPR051125;IPR003838;IPR025857;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
MT0078
false
Mycobacterium tuberculosis
894
row_412916
false
null
81,755
P9WIS1
MTQIADRPARPDETLAVAVSDITQSLTMVQAINRALYDAMAADERVLVFGEDVAVEGGVFRVTEGLADTFGADRCFDTPLAESAIIGIAVGLALRGFVPVPEIQFDGFSYPAFDQVVSHLAKYRTRTRGEVDMPVTVRIPSFGGIGAAEHHSDSTESYWVHTAGLKVVVPSTPGDAYWLLRHAIACPDPVMYLEPKRRYHGRGMVDTSRPEPPIGHAMVRRSGTDVTVVTYGNLVSTALSSADTAEQQHDWSLEVIDLRSLAPLDFDTIAASIQRTGRCVVMHEGPRSLGYGAGLAARIQEEMFYQLEAPVLRACGFDTPYPPARLEKLWLPGPDRLLDCVERVLRQP
3-methyl-2-oxobutanoate dehydrogenase subunit beta (EC 1.2.4.4) (Branched-chain alpha-ketoacid dehydrogenase E1 component subunit beta) (BCKADH E1-beta)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
348
38,064
Oxidoreductase;Reference proteome;Thiamine pyrophosphate
GO:0000287; GO:0003863; GO:0005886; GO:0007584; GO:0009083; GO:0009274
Evidence at protein level
4
null
null
null
PF02779;PF02780;
IPR029061;IPR009014;IPR005475;IPR033248;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
bkdB pdhB Rv2496c
false
Mycobacterium tuberculosis
895
row_72202
false
null
321,172
A1KP90
MARPMGKLPSNTRKCAQCAMAEALLEIAGQTINQKDLGRSGRMTRTDNDTWDLASSVGATATMIATARALASRAENPLINDPFAEPLVRAVGIDLFTRLASGELRLEDIGDHATGGRWMIDNIAIRTKFYDDFFGDATTAGIRQVVILAAGLDTRAYRLPWPPGTVVYEIDQPAVIKFKTRALANLNAEPNAERHAVAVDLRNDWPTALKNAGFDPARPTAFSAEGLLSYLPPQGQDRLLDAITALSAPDSRLATQSPLVLDLAEEDEKKMRMKSAAEAWRERGFDLDLTELIYFDQRNDVADYLAGSGWQVTTSTGKELFAAQGLPPFEDDHITRFADRRYISAVLK
Putative S-adenosyl-L-methionine-dependent methyltransferase BCG_3469 (EC 2.1.1.-)
Mycobacterium bovis (strain BCG / Pasteur 1173P2)
410,289
348
38,198
Methyltransferase;S-adenosyl-L-methionine;Transferase
GO:0008168; GO:0032259
Inferred from homology
2
null
null
null
PF04072;
IPR007213;IPR029063;IPR011610;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype), Mycobacterium tuberculosis variant bovis BCG (no rank)
BCG_3469
false
Mycobacterium tuberculosis
896
row_304544
false
null
431,784
P9WKV7
MTNPQGPPNDPSPWARPGDQGPLARPPASSEASTGRLRPGEPAGHIQEPVSPPTQPEQQPQTEHLAASHAHTRRSGRQAAHQAWDPTGLLAAQEEEPAAVKTKRRARRDPLTVFLVLIIVFSLVLAGLIGGELYARHVANSKVAQAVACVVKDQATASFGVAPLLLWQVATRHFTNISVETAGNQIRDAKGMQIKLTIQNVRLKNTPNSRGTIGALDATITWSSEGIKESVQNAIPILGAFVTSSVVTHPADGTVELKGLLNNITAKPIVAGKGLELQIINFNTLGFSLPKETVQSTLNEFTSSLTKNYPLGIHADSVQVTSTGVVSRFSTRDAAIPTGIQNPCFSHI
Uncharacterized protein Rv0479c
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
348
37,048
Cell membrane;Membrane;Reference proteome;Transmembrane;Transmembrane helix
GO:0005886
Evidence at protein level
2
SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
null
TRANSMEM 111..131; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 235..255; /note="Helical"; /evidence="ECO:0000255"
PF11209;
IPR021373;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
Rv0479c MTCY20G9.05c
false
Mycobacterium tuberculosis
897
row_413539
false
null
81,698
P9WGZ1
MLISQRPTLSEDVLTDNRSQFVIEPLEPGFGYTLGNSLRRTLLSSIPGAAVTSIRIDGVLHEFTTVPGVKEDVTEIILNLKSLVVSSEEDEPVTMYLRKQGPGEVTAGDIVPPAGVTVHNPGMHIATLNDKGKLEVELVVERGRGYVPAVQNRASGAEIGRIPVDSIYSPVLKVTYKVDATRVEQRTDFDKLILDVETKNSISPRDALASAGKTLVELFGLARELNVEAEGIEIGPSPAEADHIASFALPIDDLDLTVRSYNCLKREGVHTVGELVARTESDLLDIRNFGQKSIDEVKIKLHQLGLSLKDSPPSFDPSEVAGYDVATGTWSTEGAYDEQDYAETEQL
DNA-directed RNA polymerase subunit alpha (RNAP subunit alpha) (EC 2.7.7.6) (RNA polymerase subunit alpha) (Transcriptase subunit alpha)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
347
37,706
3D-structure;DNA-directed RNA polymerase;Nucleotidyltransferase;Reference proteome;Transcription;Transferase
GO:0000428; GO:0003677; GO:0003899; GO:0005737; GO:0005829; GO:0005886; GO:0006351; GO:0009274; GO:0046983
Evidence at protein level
4
null
null
null
PF01000;PF03118;PF01193;
IPR011262;IPR011263;IPR011773;IPR036603;IPR011260;IPR036643;
5UH5;5UH6;5UH8;5UH9;5UHA;5UHB;5UHC;5UHD;5UHE;5UHF;5UHG;5ZX2;5ZX3;6BZO;6C04;6C05;6C06;6DV9;6DVB;6DVC;6DVD;6DVE;6EDT;6EE8;6EEC;6FBV;6JCX;6JCY;6KON;6KOO;6KOP;6KOQ;6M7J;6TYE;6TYF;6TYG;6VVX;6VVY;6VVZ;6VW0;7KIF;7KIM;7KIN;7PP4;7Q4U;7Q59;7RWI;7U22;7Z8Q;7ZF2;8E74;8E79;8E82;8E8M;8E95;8EHQ;8EJ3;8EOE;8EOF;8EOS;8EOT;8EXY;8HIH;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
rpoA Rv3457c MTCY13E12.10c
false
Mycobacterium tuberculosis
898
row_72146
false
null
212,646
P9WIV3
MNIDMAALHAIEVDRGISVNELLETIKSALLTAYRHTQGHQTDARIEIDRKTGVVRVIARETDEAGNLISEWDDTPEGFGRIAATTARQVMLQRFRDAENERTYGEFSTREGEIVAGVIQRDSRANARGLVVVRIGTETKASEGVIPAAEQVPGESYEHGNRLRCYVVGVTRGAREPLITLSRTHPNLVRKLFSLEVPEIADGSVEIVAVAREAGHRSKIAVRSNVAGLNAKGACIGPMGQRVRNVMSELSGEKIDIIDYDDDPARFVANALSPAKVVSVSVIDQTARAARVVVPDFQLSLAIGKEGQNARLAARLTGWRIDIRGDAPPPPPGQPEPGVSRGMAHDR
Transcription termination/antitermination protein NusA
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
347
37,642
3D-structure;Cytoplasm;Reference proteome;Repeat;RNA-binding;Transcription;Transcription antitermination;Transcription regulation;Transcription termination
GO:0003700; GO:0003723; GO:0005829; GO:0005886; GO:0006353; GO:0009274; GO:0031564
Evidence at protein level
3
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00945}.
null
null
PF13184;PF08529;
IPR015946;IPR025249;IPR009019;IPR012340;IPR030842;IPR036555;IPR003029;IPR013735;IPR010213;
1K0R;2ASB;2ATW;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
nusA Rv2841c MTCY16B7.01 MTCY24A1.16
false
Mycobacterium tuberculosis
899
row_198853
false
null
538,147
O53565
MEAGMKLGLQLGYWGAQPPQNHAELVAAAEDAGFDTVFTAEAWGSDAYTPLAWWGSSTQRVRLGTSVIQLSARTPTACAMAALTLDHLSGGRHILGLGVSGPQVVEGWYGQRFPKPLARTREYIDIVRQVWARESPVTSAGPHYRLPLTGEGTTGLGKALKPITHPLRADIPIMLGAEGPKNVALAAEICDGWLPIFYSPRMAGMYNEWLDEGFARPGARRSREDFEICATAQVVITDDRAAAFAGIKPFLALYMGGMGAEETNFHADVYRRMGYTQVVDEVTKLFRSGRKDEAAEIIPDELVDDAVIVGDIDHVRKQMAVWEAAGVTMMVVTAGSAEQVRDLAALV
Putative coenzyme F420-dependent oxidoreductase Rv3520c (EC 1.-.-.-)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
347
37,617
Oxidoreductase;Reference proteome
GO:0005886; GO:0009274; GO:0016705
Evidence at protein level
1
null
null
null
PF00296;
IPR050564;IPR019951;IPR011251;IPR036661;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
Rv3520c
false
Mycobacterium tuberculosis
900
row_518451
false
null
26,927
P9WMK5
MTDMWDVRITDTSLRDGSHHKRHQFTKDEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYGFSKTPEQELIKLAAATAKEARIAFLMLPGVGTKDDIKEARDNGGSICRIATHCTEADVSIQHFGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVADRVSALVAELGEDAQVGFHGHENLGLGVANSVAAVRAGAKQIDGSCRRFGAGAGNAPVEALIGVFDKIGVKTGIDFFDIADAAEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQAERYGVPASALLHRAGQRKLIGGQEDQLIDIALEIKRELDSGAAVTH
4-hydroxy-2-oxohexanoate aldolase (EC 4.1.3.43) (4-hydroxy-2-keto-pentanoic acid aldolase) (4-hydroxy-2-oxopentanoate aldolase) (4-hydroxy-2-oxovalerate aldolase) (HOA) (EC 4.1.3.39)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
346
36,442
3D-structure;Aromatic hydrocarbons catabolism;Cobalt;Lyase;Manganese;Metal-binding;Nickel;Reference proteome
GO:0003852; GO:0008701; GO:0009056; GO:0009098; GO:0009274; GO:0030145
Evidence at protein level
5
null
null
null
PF07836;PF00682;
IPR050073;IPR017629;IPR013785;IPR012425;IPR035685;IPR000891;
4JN6;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
hsaF Rv3534c
false
Mycobacterium tuberculosis
901
row_23568
false
null
81,726
P9WI27
MDFTIFPPEFNSLNIQGSARPFLVAANAWKNLSNELSYAASRFESEINGLITSWRGPSSTIMAAAVAPFRAWIVTTASLAELVADHISVVAGAYEAAHAAHVPLPVIETNRLTRLALATTNIFGIHTPAIFALDALYAQYWSQDGEAMNLYATMAAAAARLTPFSPPAPIANPGALARLYELIGSVSETVGSFAAPATKNLPSKLWTLLTKGTYPLTAARISSIPVEYVLAFVEGSNMGQMMGNLAMRSLTPTLKGPLELLPNAVRPAVSATLGNADTIGGLSVPPSWVADKSITPLAKAVPTSAPGGPSGTSWAQLGLASLAGGAVGAVAARTRSGVILRSPAAG
PPE family protein PPE17
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
346
35,821
Cell wall;Reference proteome;Secreted;Virulence
GO:0005576; GO:0009986; GO:0052572
Evidence at protein level
4
SUBCELLULAR LOCATION: Secreted, cell wall {ECO:0000269|PubMed:22427668, ECO:0000269|PubMed:23469198}. Cell surface {ECO:0000269|PubMed:23469198}. Note=Not secreted but surface exposed. Mainly localized in the cell wall fraction regardless of PE11 co-expression. {ECO:0000269|PubMed:23469198}.
null
null
PF00823;PF12484;
IPR022171;IPR000030;IPR038332;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
PPE17 Rv1168c
false
Mycobacterium tuberculosis
902
row_72174
false
null
207,449
P63988
MPTAAPRWILHVDLDQFLASVELLRHPELAGLPVIVGGNGDPTEPRKVVTCASYEARAYGVRAGMPLRTAARRCPEATFLPSNPAAYNAASEEVVALLRDLGYPVEVWGWDEAYLAVAPGTPDDPIEVAEEIRKVILSQTGLSCSIGISDNKQRAKIATGLAKPAGIYQLTDANWMAIMGDRTVEALWGVGPKTTKRLAKLGINTVYQLAHTDSGLLMSTFGPRTALWLLLAKGGGDTEVSAQAWVPRSRSHAVTFPRDLTCRSEMESAVTELAQRTLNEVVASSRTVTRVAVTVRTATFYTRTKIRKLQAPSTDPDVITAAARHVLDLFELDRPVRLLGVRLELA
DNA polymerase IV 2 (Pol IV 2) (EC 2.7.7.7)
Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
233,413
346
37,562
Cytoplasm;DNA damage;DNA repair;DNA replication;DNA-binding;DNA-directed DNA polymerase;Magnesium;Metal-binding;Mutator protein;Nucleotidyltransferase;Reference proteome;Transferase
GO:0000287; GO:0003684; GO:0003887; GO:0005829; GO:0006261; GO:0009432; GO:0042276
Inferred from homology
3
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
null
null
PF00817;PF11799;
IPR043502;IPR036775;IPR017961;IPR050116;IPR022880;IPR043128;IPR001126;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype)
dinB2 dinP BQ2027_MB3082
false
Mycobacterium tuberculosis
903
row_193872
false
null
213,210
P9WQC5
MSTVAAYAAMSATEPLTKTTITRRDPGPHDVAIDIKFAGICHSDIHTVKAEWGQPNYPVVPGHEIAGVVTAVGSEVTKYRQGDRVGVGCFVDSCRECNSCTRGIEQYCKPGANFTYNSIGKDGQPTQGGYSEAIVVDENYVLRIPDVLPLDVAAPLLCAGITLYSPLRHWNAGANTRVAIIGLGGLGHMGVKLGAAMGADVTVLSQSLKKMEDGLRLGAKSYYATADPDTFRKLRGGFDLILNTVSANLDLGQYLNLLDVDGTLVELGIPEHPMAVPAFALALMRRSLAGSNIGGIAETQEMLNFCAEHGVTPEIELIEPDYINDAYERVLASDVRYRFVIDISAL
NADP-dependent alcohol dehydrogenase C (EC 1.1.1.2)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
346
37,075
Acetylation;Isopeptide bond;Metal-binding;NADP;Oxidoreductase;Reference proteome;Ubl conjugation;Zinc
GO:0005829; GO:0005886; GO:0008106; GO:0008270; GO:0009274; GO:0016616
Evidence at protein level
3
null
null
null
PF08240;PF00107;
IPR013149;IPR013154;IPR002328;IPR047109;IPR011032;IPR036291;IPR020843;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
adhC adh Rv3045 MTV012.60
false
Mycobacterium tuberculosis
904
row_199408
false
null
431,848
P9WLV5
MSIVSISYNQEEYIREALDGFAAQRTEFPVEVIIADDASTDATPRIIGEYAARYPQLFRPILRQTNIGVHANFKDVLSAARGEYLALCEGDDYWTDPLKLSKQVKYLDRHPETTVCFHPVRVIYEDGAKDSEFPPLSWRRDLSVDALLARNFIQTNSVVYRRQPSYDDIPANVMPIDWYLHVRHAVGGEIAMLPETMAVYRRHAHGIWHSAYTDRRKFWETRGHGMAATLEAMLDLVHGHREREAIVGEVSAWVLREIGKTPGRQGRALLLKSIADHPRMTMLSLQHRWAQTPWRRFKRRLSTELSSLAALAYATRRRALEGRDGGYRETTSPPTGRGRNVRGSHA
Uncharacterized protein Rv1520
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
346
39,578
Reference proteome
GO:0005886; GO:0009058; GO:0009274; GO:0016757; GO:0016758
Evidence at protein level
2
null
null
null
PF00535;
IPR001173;IPR029044;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
Rv1520 MTCY19G5.08c
false
Mycobacterium tuberculosis
905
row_413603
false
null
432,227
P9WQC0
MVSPATTATMSAWQVRRPGPMDTGPLERVTTRVPRPAPSELLVAVHACGVCRTDLHVTEGDLPVHRERVIPGHEVVGEVIEVGSAVGAAAGGEFDRGDRVGIAWLRHTCGVCKYCRRGSENLCPQSRYTGWDADGGYAEFTTVPAAFAHHLPSGYSDSELAPLLCAGIIGYRSLLRTELPPGGRLGLYGFGGSAHITAQVALAQGAEIHVMTRGARARKLALQLGAASAQDAADRPPVPLDAAILFAPVGDLVLPALEALDRGGILAIAGIHLTDIPDLNYQQHLFQERQIRSVTSNTRADARAFFDFAAQHHIEVTTPEYPLGQADRALGDLSAGRIAGAAVLLI
Probable alcohol dehydrogenase AdhA (EC 1.1.1.1)
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
83,331
346
36,632
Metal-binding;NAD;Oxidoreductase;Reference proteome;Zinc
GO:0004022; GO:0005737; GO:0008270
Inferred from homology
2
null
null
null
PF08240;
IPR013154;IPR002328;IPR014187;IPR011032;IPR036291;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
adhA MT1911
false
Mycobacterium tuberculosis
906
row_413972
false
null
544,662
P64766
MAGVSEAERRGHRKLVRFQARRAIGPIRPTSAAWDRDFDPAGKRIAVVGTDAAAAHYISRLSESAASVTVFTQAPRRVVTGVPLWTTRAKRWLRRRTGAEHPAVAWATAAIDALTSSGIRTSDGVEHPVDAIIYGTGFAIADQVGDQTLVGAGGVTIRQAWDDGMEPYLGVAVHGFPNYFFITGPDTAAQARCVVECMKLMERTASRRIEVRRSSQQVFNERAQLKPAQPHRQTGGLEAFDLSSAATEDDQTYDGAATLTLAGARFRVRVRLTGHLDPIDGNYHWQGTVFDSLPETSLTHARAATLTIGGRSAPARITEQTPWGTHSVAGVGPPPYARSGPASATT
Uncharacterized protein Mb0968c
Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
233,413
346
37,206
Reference proteome
null
Predicted
1
null
null
null
PF16170;
IPR032371;IPR051209;IPR036188;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype)
BQ2027_MB0968C
false
Mycobacterium tuberculosis
907
row_524905
false
null
26,994
P9WNX5
MGLSIGIVGATGQVGQVMRTLLDERDFPASAVRFFASARSQGRKLAFRGQEIEVEDAETADPSGLDIALFSAGSAMSKVQAPRFAAAGVTVIDNSSAWRKDPDVPLVVSEVNFERDAHRRPKGIIANPNCTTMAAMPVLKVLHDEARLVRLVVSSYQAVSGSGLAGVAELAEQARAVIGGAEQLVYDGGALEFPPPNTYVAPIAFNVVPLAGSLVDDGSGETDEDQKLRFESRKILGIPDLLVSGTCVRVPVFTGHSLSINAEFAQPLSPERARELLDGATGVQLVDVPTPLAAAGVDESLVGRIRRDPGVPDGRGLALFVSGDNLRKGAALNTIQIAELLTADL
Aspartate-semialdehyde dehydrogenase (ASA dehydrogenase) (ASADH) (EC 1.2.1.11) (Aspartate-beta-semialdehyde dehydrogenase)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
345
36,230
3D-structure;Amino-acid biosynthesis;Diaminopimelate biosynthesis;Lysine biosynthesis;Methionine biosynthesis;NADP;Oxidoreductase;Reference proteome;Threonine biosynthesis;Virulence
GO:0004073; GO:0005886; GO:0009088; GO:0009089; GO:0009097; GO:0009274; GO:0019877; GO:0046983; GO:0050661; GO:0051287; GO:0071266
Evidence at protein level
5
null
null
null
PF01118;PF02774;
IPR000319;IPR012080;IPR005986;IPR036291;IPR000534;IPR012280;
3TZ6;3VOS;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
asd Rv3708c MTV025.056c
false
Mycobacterium tuberculosis
908
row_23633
false
null
431,841
P9WLQ7
MDVLSAVLLALLLIGANAFFVGAEFALISARRDRLEALAEQGKATAVTVIRAGEQLPAMLTGAQLGVTVSSILLGRVGEPAVVKLLQLSFGLSGVPPALLHTLSLAIVVALHVLLGEMVPKNIALAGPERTAMLLVPPYLVYVRLARPFIAFYNNCANAILRLVGVQPKDELDIAVSTAELSEMIAESLSEGLLDHEEHTRLTRALRIRTRLVADVAVPLVNIRAVQVSAVGSGPTIGGVEQALAQTGYSRFPVVDRGGRFIGYLHIKDVLTLGDNPQTVIDLAVVRPLPRVPQSLPLADALSRMRRINSHLALVTADNGSVVGMVALEDVVEDLVGTMRDGTHR
Uncharacterized protein Rv1841c
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
345
36,685
Cell membrane;Membrane;Reference proteome;Repeat;Transmembrane;Transmembrane helix
GO:0005886
Evidence at protein level
2
SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
null
TRANSMEM 3..23; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 95..115; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 312..332; /note="Helical"; /evidence="ECO:0000255"
PF00571;PF01595;
IPR000644;IPR046342;IPR002550;IPR044751;IPR051676;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
Rv1841c MTCY1A11.03 MTCY359.32
false
Mycobacterium tuberculosis
909
row_413596
false
null
4,617
O06218
MKFVNHIEPVAPRRAGGAVAEVYAEARREFGRLPEPLAMLSPDEGLLTAGWATLRETLLVGQVPRGRKEAVAAAVAASLRCPWCVDAHTTMLYAAGQTDTAAAILAGTAPAAGDPNAPYVAWAAGTGTPAGPPAPFGPDVAAEYLGTAVQFHFIARLVLVLLDETFLPGGPRAQQLMRRAGGLVFARKVRAEHRPGRSTRRLEPRTLPDDLAWATPSEPIATAFAALSHHLDTAPHLPPPTRQVVRRVVGSWHGEPMPMSSRWTNEHTAELPADLHAPTRLALLTGLAPHQVTDDDVAAARSLLDTDAALVGALAWAAFTAARRIGTWIGAAAEGQVSRQNPTG
Alkyl hydroperoxide reductase Rv2159c (EC 1.11.1.-) (Alkylhydroperoxidase Rv2159c)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
344
36,376
Oxidoreductase;Peroxidase;Reference proteome;Virulence
GO:0005886; GO:0009274; GO:0051920
Evidence at protein level
5
null
null
null
PF02627;
IPR029032;IPR004675;IPR003779;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
Rv2159c
false
Mycobacterium tuberculosis
910
row_3697
false
null
81,720
P9WHV5
MRLGVLDVGSNTVHLLVVDAHRGGHPTPMSSTKATLRLAEATDSSGKITKRGADKLISTIDEFAKIAISSGCAELMAFATSAVRDAENSEDVLSRVRKETGVELQALRGEDESRLTFLAVRRWYGWSAGRILNLDIGGGSLEVSSGVDEEPEIALSLPLGAGRLTREWLPDDPPGRRRVAMLRDWLDAELAEPSVTVLEAGSPDLAVATSKTFRSLARLTGAAPSMAGPRVKRTLTANGLRQLIAFISRMTAVDRAELEGVSADRAPQIVAGALVAEASMRALSIEAVEICPWALREGLILRKLDSEADGTALIESSSVHTSVRAVGGQPADRNAANRSRGSKP
Exopolyphosphatase 1 (ExopolyPase 1) (EC 3.6.1.11) (MTB-PPX1)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
344
36,550
Direct protein sequencing;Hydrolase;Manganese;Reference proteome
GO:0004309; GO:0016462
Evidence at protein level
4
null
null
null
PF02541;
IPR043129;IPR050273;IPR003695;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
ppx1 Rv0496 MTCY20G9.22
false
Mycobacterium tuberculosis
911
row_72168
false
null
81,764
P9WIZ7
MTAAVDGKGPAAMNTHFPDAETVRTVLTLAVRAPSIHNTQPWRWRVCPTSLELFSRPDMQLRSTDPDGRELILSCGVALHHCVVALASLGWQAKVNRFPDPKDRCHLATIGVQPLVPDQADVALAAAIPRRRTDRRAYSCWPVPGGDIALMAARAARGGVMLRQVSALDRMKAIVAQAVLDHVTDEEYLRELTIWSGRYGSVAGVPARNEPPSDPSAPIPGRLFAGPGLSQPSDVLPADDGAAILALGTETDDRLARLRAGEAASIVLLTATAMGLACCPITEPLEIAKTRDAVRAEVFGAGGYPQMLLRVGWAPINADPLPPTPRRELSQVVEWPEELLRQRC
Putative NAD(P)H nitroreductase Rv3131
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
344
37,049
Direct protein sequencing;Flavoprotein;FMN;NAD;NADP;Oxidoreductase;Reference proteome;Virulence
GO:0005829; GO:0005886; GO:0016491
Evidence at protein level
4
null
null
null
null
IPR000415;IPR050627;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
Rv3131
false
Mycobacterium tuberculosis
912
row_72211
false
null
81,869
P9WNE3
MQFDAVLLLSFGGPEGPEQVRPFLENVTRGRGVPAERLDAVAEHYLHFGGVSPINGINRTLIAELEAQQELPVYFGNRNWEPYVEDAVTAMRDNGVRRAAVFATSAWSGYSSCTQYVEDIARARRAAGRDAPELVKLRPYFDHPLFVEMFADAITAAAATVRGDARLVFTAHSIPTAADRRCGPNLYSRQVAYATRLVAAAAGYCDFDLAWQSRSGPPQVPWLEPDVTDQLTGLAGAGINAVIVCPIGFVADHIEVVWDLDHELRLQAEAAGIAYARASTPNADPRFARLARGLIDELRYGRIPARVSGPDPVPGCLSSINGQPCRPPHCVASVSPARPSAGSP
Coproporphyrin III ferrochelatase (EC 4.99.1.9)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
344
37,144
2Fe-2S;Cytoplasm;Heme biosynthesis;Iron;Iron-sulfur;Lyase;Metal-binding;Porphyrin biosynthesis;Reference proteome
GO:0004325; GO:0005737; GO:0005886; GO:0006783; GO:0046872; GO:0051537
Evidence at protein level
4
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00323}.
null
null
PF00762;
IPR001015;IPR019772;IPR033644;IPR033659;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
cpfC hemH hemZ Rv1485 MTCY277.06
false
Mycobacterium tuberculosis
913
row_72312
false
null
81,946
P9WQA3
MPIATPEVYAEMLGQAKQNSYAFPAINCTSSETVNAAIKGFADAGSDGIIQFSTGGAEFGSGLGVKDMVTGAVALAEFTHVIAAKYPVNVALHTDHCPKDKLDSYVRPLLAISAQRVSKGGNPLFQSHMWDGSAVPIDENLAIAQELLKAAAAAKIILEIEIGVVGGEEDGVANEINEKLYTSPEDFEKTIEALGAGEHGKYLLAATFGNVHGVYKPGNVKLRPDILAQGQQVAAAKLGLPADAKPFDFVFHGGSGSLKSEIEEALRYGVVKMNVDTDTQYAFTRPIAGHMFTNYDGVLKVDGEVGVKKVYDPRSYLKKAEASMSQRVVQACNDLHCAGKSLTH
Fructose-bisphosphate aldolase (FBP aldolase) (FBPA) (EC 4.1.2.13) (Fructose-1,6-bisphosphate aldolase)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
344
36,544
3D-structure;Glycolysis;Lyase;Metal-binding;Reference proteome;Zinc
GO:0004332; GO:0005576; GO:0005829; GO:0005886; GO:0006096; GO:0008270; GO:0009274; GO:0035375
Evidence at protein level
4
null
null
null
PF01116;
IPR013785;IPR000771;IPR006411;
3EKL;3EKZ;3ELF;4A21;4A22;4DEF;4DEL;4LV4;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
fba Rv0363c MTCY13E10.25c
false
Mycobacterium tuberculosis
914
row_72383
false
null
112,228
A1KLU0
MTERSDRDVSPALTVGEGDIDVSLRPRSLREFIGQPRVREQLQLVIEGAKNRGGTPDHILLSGPPGLGKTSLAMIIAAELGSSLRVTSGPALERAGDLAAMLSNLVEHDVLFIDEIHRIARPAEEMLYLAMEDFRVDVVVGKGPGATSIPLEVAPFTLVGATTRSGALTGPLRDRFGFTAHMDFYEPAELERVLARSAGILGIELGADAGAEIARRSRGTPRIANRLLRRVRDFAEVRADGVITRDVAKAALEVYDVDELGLDRLDRAVLSALTRSFGGGPVGVSTLAVAVGEEAATVEEVCEPFLVRAGMVARTPRGRVATALAWTHLGMTPPVGASQPGLFE
Holliday junction branch migration complex subunit RuvB (EC 3.6.4.-)
Mycobacterium bovis (strain BCG / Pasteur 1173P2)
410,289
344
36,627
ATP-binding;Cytoplasm;DNA damage;DNA recombination;DNA repair;DNA-binding;Hydrolase;Nucleotide-binding
GO:0000400; GO:0005524; GO:0005737; GO:0006281; GO:0006310; GO:0009378; GO:0016887; GO:0048476
Inferred from homology
3
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00016}.
null
null
PF17864;PF05491;PF05496;
IPR003593;IPR041445;IPR004605;IPR027417;IPR008824;IPR008823;IPR036388;IPR036390;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype), Mycobacterium tuberculosis variant bovis BCG (no rank)
ruvB BCG_2615c
false
Mycobacterium tuberculosis
915
row_100693
false
null
112,275
A1KPB0
MTTVLGIETSCDETGVGIARLDPDGTVTLLADEVASSVDEHVRFGGVVPEIASRAHLEALGPAMRRALAAAGLKQPDIVAATIGPGLAGALLVGVAAAKAYSAAWGVPFYAVNHLGGHLAADVYEHGPLPECVALLVSGGHTHLLHVRSLGEPIIELGSTVDDAAGEAYDKVARLLGLGYPGGKALDDLARTGDRDAIVFPRGMSGPADDRYAFSFSGLKTAVARYVESHAADPGFRTADIAAGFQEAVADVLTMKAVRAATALGVSTLLIAGGVAANSRLRELATQRCGEAGRTLRIPSPRLCTDNGAMIAAFAAQLVAAGAPPSPLDVPSDPGLPVMQGQVR
tRNA N6-adenosine threonylcarbamoyltransferase (EC 2.3.1.234) (N6-L-threonylcarbamoyladenine synthase) (t(6)A synthase) (t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD) (tRNA threonylcarbamoyladenosine biosynthesis protein TsaD)
Mycobacterium bovis (strain BCG / Pasteur 1173P2)
410,289
344
35,091
Acyltransferase;Cytoplasm;Iron;Metal-binding;Transferase;tRNA processing
GO:0002949; GO:0005506; GO:0005737; GO:0061711
Inferred from homology
3
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01445}.
null
null
PF00814;
IPR043129;IPR000905;IPR017861;IPR017860;IPR022450;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype), Mycobacterium tuberculosis variant bovis BCG (no rank)
tsaD gcp BCG_3489c
false
Mycobacterium tuberculosis
916
row_100740
false
null
212,613
P9WIJ9
MTQPSRRKGGLGRGLAALIPTGPADGESGPPTLGPRMGSATADVVIGGPVPDTSVMGAIYREIPPSAIEANPRQPRQVFDEEALAELVHSIREFGLLQPIVVRSLAGSQTGVRYQIVMGERRWRAAQEAGLATIPAIVRETGDDNLLRDALLENIHRVQLNPLEEAAAYQQLLDEFGVTHDELAARIGRSRPLITNMIRLLKLPIPVQRRVAAGVLSAGHARALLSLEAGPEAQEELASRIVAEGLSVRATEETVTLANHEANRQAHHSDATTPAPPRRKPIQMPGLQDVAERLSTTFDTRVTVSLGKRKGKIVVEFGSVDDLARIVGLMTTDGRDKGLHRDAL
Probable chromosome-partitioning protein ParB
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
344
37,018
Chromosome partition;DNA-binding;Reference proteome
GO:0003677; GO:0005576; GO:0005694; GO:0005886; GO:0007059; GO:0045881; GO:0060187
Evidence at protein level
3
null
null
null
PF17762;PF23552;PF02195;
IPR050336;IPR041468;IPR004437;IPR003115;IPR036086;IPR057240;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
parB Rv3917c MTV028.08c
false
Mycobacterium tuberculosis
917
row_198821
false
null
425,783
P64812
MNSITDVGGIRVGHYQRLDPDASLGAGWACGVTVVLPPPGTVGAVDCRGGAPGTRETDLLDPANSVRFVDALLLAGGSAYGLAAADGVMRWLEEHRRGVAMDSGVVPIVPGAVIFDLPVGGWNCRPTADFGYSACAAAGVDVAVGTVGVGVGARAGALKGGVGTASATLQSGVTVGVLAVVNAAGNVVDPATGLPWMADLVGEFALRAPPAEQIAALAQLSSPLGAFNTPFNTTIGVIACDAALSPAACRRIAIAAHDGLARTIRPAHTPLDGDTVFALATGAVAVPPEAGVPAALSPETQLVTAVGAAAADCLARAVLAGVLNAQPVAGIPTYRDMFPGAFGS
Uncharacterized aminopeptidase Mb1368 (EC 3.4.11.-)
Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
233,413
344
33,953
Aminopeptidase;Cell membrane;Hydrolase;Membrane;Protease;Reference proteome;Transmembrane;Transmembrane helix
GO:0004177; GO:0005886; GO:0006508
Inferred from homology
2
SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
null
TRANSMEM 25..45; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 68..88; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 104..124; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 133..153; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 161..181; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 224..244; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 276..296; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 302..322; /note="Helical"; /evidence="ECO:0000255"
PF03576;
IPR016117;IPR005321;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype)
BQ2027_MB1368
false
Mycobacterium tuberculosis
918
row_407877
false
null
431,795
P9WL06
MLKNAVLLACRAPSVHNSQPWRWVAESGSEHTTVHLFVNRHRTVPATDHSGRQAIISCGAVLDHLRIAMTAAHWQANITRFPQPNQPDQLATVEFSPIDHVTAGQRNRAQAILQRRTDRLPFDSPMYWHLFEPALRDAVDKDVAMLDVVSDDQRTRLVVASQLSEVLRRDDPYYHAELEWWTSPFVLAHGVPPDTLASDAERLRVDLGRDFPVRSYQNRRAELADDRSKVLVLSTPSDTRADALRCGEVLSTILLECTMAGMATCTLTHLIESSDSRDIVRGLTRQRGEPQALIRVGIAPPLAAVPAPTPRRPLDSVLQIRQTPEKGRNASDRNARETGWFSPP
Uncharacterized protein MT3212
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
83,331
344
38,521
Reference proteome
GO:0016491
Evidence at transcript level
2
null
null
null
null
IPR000415;IPR050627;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
MT3212
false
Mycobacterium tuberculosis
919
row_413550
false
null
431,912
P9WMJ1
MGHLPPPAEVRHPVYATRVLCEVANERGVPTADVLAGTAIEPADLDDPDAVVGALDEITAVRRLLARLPDDAGIGIDVGSRFALTHFGLFGFAVMSCGTLRELLTIAMRYFALTTMHVDITLFETADDCLVELDASHLPADVRGFFIERDIAGIIATTTSFALPLAAKYADQVSAELAVDAELLRPLLELVPVHDVAFGRAHNRVHFPRAMFDEPLPQADRHTLEMCIAQCDVLMQRNERRRGITALVRSKLFRDSGLFPTFTDVAGELDMHPRTLRRRLAEEGTSFRALLGEARSTVAVDLLRNVGLTVQQVSTRLGYTEVSTFSHAFKRWYGVAPSEYSRRG
Uncharacterized HTH-type transcriptional regulator Rv1395
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
344
37,894
DNA-binding;Reference proteome;Transcription;Transcription regulation
GO:0000976; GO:0003677; GO:0003700
Evidence at protein level
2
null
null
null
PF12625;PF12833;
IPR032687;IPR009057;IPR018060;IPR020449;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
Rv1395 MTCY21B4.12
false
Mycobacterium tuberculosis
920
row_413667
false
null
26,826
P9WID7
MRIGVLTGGGDCPGLNAVIRAVVRTCHARYGSSVVGFQNGFRGLLENRRVQLHNDDRNDRLLAKGGTMLGTARVHPDKLRAGLPQIMQTLDDNGIDVLIPIGGEGTLTAASWLSEENVPVVGVPKTIDNDIDCTDVTFGHDTALTVATEAIDRLHSTAESHERVMLVEVMGRHAGWIALNAGLASGAHMTLIPEQPFDIEEVCRLVKGRFQRGDSHFICVVAEGAKPAPGTIMLREGGLDEFGHERFTGVAAQLAVEVEKRINKDVRVTVLGHIQRGGTPTAYDRVLATRFGVNAADAAHAGEYGQMVTLRGQDIGRVPLADAVRKLKLVPQSRYDDAAAFFG
ATP-dependent 6-phosphofructokinase (ATP-PFK) (Phosphofructokinase) (EC 2.7.1.11) (Phosphofructokinase A) (Phosphohexokinase) (Tagatose-6-phosphate kinase) (EC 2.7.1.144)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
343
36,880
Allosteric enzyme;ATP-binding;Cytoplasm;Glycolysis;Kinase;Magnesium;Metal-binding;Nucleotide-binding;Reference proteome;Transferase
GO:0003872; GO:0005524; GO:0005886; GO:0005945; GO:0006002; GO:0009024; GO:0009274; GO:0030388; GO:0046872; GO:0047334; GO:0061621; GO:0070095
Evidence at protein level
5
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01976}.
null
null
PF00365;
IPR022953;IPR012003;IPR015912;IPR000023;IPR012829;IPR035966;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
pfkA Rv3010c MTV012.24c
false
Mycobacterium tuberculosis
921
row_23471
false
null
431,917
P9WMK3
MGSADERRFEVLRAIVADFVATQEPIGSKSLVERHNLGVSSATVRNDMAVLEAEGYITQPHTSSGRVPTEKGYREFVDRLEDVKPLSSAERRAIQSFLESGVDLDDVLRRAVRLLAQLTRQVAVVQYPTLSTSTVRHLEVIALTPARLLMVVITDSGRVDQRIVELGDVIDDHQLAQLREILGQALEGKKLSAASVAVADLASQLGGAGGLGDAVGRAATVLLESLVEHTEERLLLGGTANLTRNAADFGGSLRSILEALEEQVVVLRLLAAQQEAGKVTVRIGHETASEQMVGTSMVSTAYGTAHTVYGGMGVVGPTRMDYPGTIASVAAVALYIGDVLGAR
Heat-inducible transcription repressor HrcA
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
343
36,475
Reference proteome;Repressor;Stress response;Transcription;Transcription regulation
GO:0003677; GO:0005886; GO:0045892
Evidence at protein level
2
null
null
null
PF01628;
IPR029016;IPR002571;IPR021153;IPR036388;IPR036390;IPR023120;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
hrcA Rv2374c MTCY27.06
false
Mycobacterium tuberculosis
922
row_413672
false
null
212,896
P9WMU5
MTDGIVALGGGHGLYATLSAARRLTPYVTAVVTVADDGGSSGRLRSELDVVPPGDLRMALAALASDSPHGRLWATILQHRFGGSGALAGHPIGNLMLAGLSEVLADPVAALDELGRILGVKGRVLPMCPVALQIEADVSGLEADPRMFRLIRGQVAIATTPGKVRRVRLLPTDPPATRQAVDAIMAADLVVLGPGSWFTSVIPHVLVPGLAAALRATSARRALVLNLVAEPGETAGFSVERHLHVLAQHAPGFTVHDIIIDAERVPSEREREQLRRTATMLQAEVHFADVARPGTPLHDPGKLAAVLDGVCARDVGASEPPVAATQEIPIDGGRPRGDDAWR
Putative gluconeogenesis factor
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
342
35,823
Cytoplasm;Phosphoprotein;Reference proteome
GO:0005737; GO:0008360; GO:0043743
Evidence at protein level
3
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00973}.
null
null
PF01933;
IPR002882;IPR038136;IPR010119;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
Rv1422 MTCY21B4.40
false
Mycobacterium tuberculosis
923
row_199099
false
null
431,952
P9WMX4
MRLSIVTTMYMSEPYVLEFYRRARAAADKITPDVEIIFVDDGSPDAALQQAVSLLDSDPCVRVIQLSRNFGHHKAMMTGLAHATGDLVFLIDSDLEEDPALLEPFYEKLISTGADVVFGCHARRPGGWLRNFGPKIHYRASALLCDPPLHENTLTVRLMTADYVRSLVQHQERELSIAGLWQITGFYQVPMSVNKAWKGTTTYTFRRKVATLVDNVTSFSNKPLVFIFYLGAAIFIISSSAAGYLIIDRIFFRALQAGWASVIVSIWMLGGVTIFCIGLVGIYVSKVFIETKQRPYTIIRRIYGSDLTTREPSSLKTAFPAAHLSNGKRVTSEPEGLATGNR
Putative glycosyltransferases (EC 2.4.-.-)
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
83,331
342
38,095
Cell membrane;Glycosyltransferase;Membrane;Reference proteome;Transferase;Transmembrane;Transmembrane helix
GO:0005886; GO:0016757
Inferred from homology
2
SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
null
TRANSMEM 227..247; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 262..282; /note="Helical"; /evidence="ECO:0000255"
PF00535;
IPR001173;IPR050256;IPR029044;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
pimF MT1549
false
Mycobacterium tuberculosis
924
row_413707
false
null
81,861
P9WN75
MAANKREPKVVVLGGGSWGTTVASICARRGPTLQWVRSAVTAQDINDNHRNSRYLGNDVVLSDTLRATTDFTEAANCADVVVMGVPSHGFRGVLVELSKELRPWVPVVSLVKGLEQGTNMRMSQIIEEVLPGHPAGILAGPNIAREVAEGYAAAAVLAMPDQHLATRLSAMFRTRRFRVYTTDDVVGVETAGALKNVFAIAVGMGYSLGIGENTRALVIARALREMTKLGVAMGGKSETFPGLAGLGDLIVTCTSQRSRNRHVGEQLGAGKPIDEIIASMSQVAEGVKAAGVVMEFANEFGLNMPIAREVDAVINHGSTVEQAYRGLIAEVPGHEVHGSGF
Glycerol-3-phosphate dehydrogenase [NAD(P)+] 1 (EC 1.1.1.94) (NAD(P)(+)-dependent glycerol-3-phosphate dehydrogenase 1) (NAD(P)H-dependent dihydroxyacetone-phosphate reductase 1)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
341
36,153
Cytoplasm;Lipid biosynthesis;Lipid metabolism;NAD;NADP;Nucleotide-binding;Oxidoreductase;Phospholipid biosynthesis;Phospholipid metabolism;Reference proteome
GO:0005829; GO:0005975; GO:0006072; GO:0006650; GO:0008654; GO:0046167; GO:0046168; GO:0047952; GO:0051287
Evidence at protein level
4
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00394}.
null
null
PF07479;PF01210;
IPR008927;IPR013328;IPR006168;IPR006109;IPR011128;IPR036291;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
gpsA1 gpdA1 Rv0564c MTV039.02c
false
Mycobacterium tuberculosis
925
row_72305
false
null
112,182
A1KJ66
MLSPEALTTAVDAAQQAIALADTLDVLARVKTEHLGDRSPLALARQALAVLPKEQRAEAGKRVNAARNAAQRSYDERLATLRAERDAAVLVAEGIDVTLPSTRVPAGARHPIIMLAEHVADTFIAMGWELAEGPEVETEQFNFDALNFPADHPARGEQDTFYIAPEDSRQLLRTHTSPVQIRTLLARELPVYIISIGRTFRTDELDATHTPIFHQVEGLAVDRGLSMAHLRGTLDAFARAEFGPSARTRIRPHFFPFTEPSAEVDVWFANKIGGADWVEWGGCGMVHPNVLRATGIDPDLYSGFAFGMGLERTLQFRNGIPDMRDMVEGDVRFSLPFGVGA
Phenylalanine--tRNA ligase alpha subunit (EC 6.1.1.20) (Phenylalanyl-tRNA synthetase alpha subunit) (PheRS)
Mycobacterium bovis (strain BCG / Pasteur 1173P2)
410,289
341
37,415
Aminoacyl-tRNA synthetase;ATP-binding;Cytoplasm;Ligase;Magnesium;Metal-binding;Nucleotide-binding;Protein biosynthesis
GO:0000049; GO:0000287; GO:0004826; GO:0005524; GO:0005737; GO:0006432
Inferred from homology
3
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00281}.
null
null
PF02912;PF01409;
IPR006195;IPR045864;IPR004529;IPR004188;IPR022911;IPR002319;IPR010978;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype), Mycobacterium tuberculosis variant bovis BCG (no rank)
pheS BCG_1688
false
Mycobacterium tuberculosis
926
row_100647
false
null
426,698
P66780
MNLGDLTNFVEKPLAAVSNIVNTPNSAGRYRPFYLRNLLDAVQGRNLNDAVKGKVVLITGGSSGIGAAAAKKIAEAGGTVVLVARTLENLENVANDIRAIRGNGGTAHVYPCDLSDMDAIAVMADQVLGDLGGVDILINNAGRSIRRSLELSYDRIHDYQRTMQLNYLGAVQLILKFIPGMRERHFGHIVNVSSVGVQTRAPRFGAYIASKAALDSLCDALQAETVHDNVRFTTVHMALVRTPMISPTTIYDKFPTLTPDQAAGVITDAIVHRPRRASSPFGQFAAVADAVNPAVMDRVRNRAFNMFGDSSAAKGSESQTDTSELDKRSETFVRATRGIHW
Uncharacterized oxidoreductase Mb1570 (EC 1.-.-.-)
Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
233,413
341
36,821
Oxidoreductase;Reference proteome
GO:0016020; GO:0016491
Inferred from homology
2
null
null
null
PF00106;
IPR036291;IPR002347;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype)
BQ2027_MB1570
false
Mycobacterium tuberculosis
927
row_408792
false
null
432,009
P9WNH3
MTERKRNLRPVRDVAPPTLQFRTVHGYRRAFRIAGSGPAILLIHGIGDNSTTWNGVHAKLAQRFTVIAPDLLGHGQSDKPRADYSVAAYANGMRDLLSVLDIERVTIVGHSLGGGVAMQFAYQFPQLVDRLILVSAGGVTKDVNIVFRLASLPMGSEAMALLRLPLVLPAVQIAGRIVGKAIGTTSLGHDLPNVLRILDDLPEPTASAAFGRTLRAVVDWRGQMVTMLDRCYLTEAIPVQIIWGTKDVVLPVRHAHMAHAAMPGSQLEIFEGSGHFPFHDDPARFIDIVERFMDTTEPAEYDQAALRALLRRGGGEATVTGSADTRVAVLNAIGSNERSAT
Uncharacterized protein Rv2715
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
341
36,933
Hydrolase;Reference proteome
GO:0005886; GO:0016787
Evidence at protein level
2
null
null
null
PF00561;
IPR000073;IPR029058;IPR050266;IPR000639;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
Rv2715 MTCY05A6.36
false
Mycobacterium tuberculosis
928
row_413759
false
null
544,752
P65010
MRDFHCPNCGQRLAFENSACLSCGSALGFSLGRMALLVIADDADVQLCANLHLAQCNWLVPSDQLGGLCSSCVLTIERPSDTNTAGLAEFARAEGAKRRLIAELHELKLPIVGRDQDPDHGLAFRLLSSAHENVTTGHQNGVITLDLAEGDDVHREQLRVEMDEPYRTLLGHFRHEIGHYYFYRLIASSSDYLSRFNELFGDPDADYSQALDRHYRGGPPEGWQDSFVSSYATMHASEDWAETFAHYLHIRDALDTAAWCGLAPASATFDRPALGPSAFNTIIDKWLPLSWSLNMVNRSMGHDDLYPFVLPAAVLEKMRFIHTVVDEVAPDFEPAHSRRTV
Uncharacterized protein Mb2598c
Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
233,413
341
38,003
Reference proteome
null
Predicted
1
null
null
null
PF15887;PF10005;
IPR031321;IPR011201;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype)
BQ2027_MB2598C
false
Mycobacterium tuberculosis
929
row_524995
false
null