Datasets:
manufernandezbur
/
tox_nontox_clustered_2025

Dataset card Data Studio Files
xet
Community
1
Unnamed: 0
int64
2
562k
Entry
stringlengths
6
10
Sequence
stringlengths
11
999
Protein names
stringlengths
5
558
Organism
stringclasses
392 values
Organism (ID)
int64
595
2.89M
Length
int64
11
999
Mass
int64
1.06k
118k
Keywords
stringlengths
4
380
⌀
Gene Ontology IDs
stringlengths
10
754
⌀
Protein existence
stringclasses
5 values
Annotation
float64
1
5
Subcellular location [CC]
stringlengths
30
2.26k
⌀
Signal peptide
stringclasses
677 values
Transmembrane
stringlengths
32
2.52k
⌀
Pfam
stringlengths
8
72
⌀
InterPro
stringlengths
10
180
⌀
PDB
stringlengths
5
2.65k
⌀
Taxonomic lineage
stringclasses
178 values
Gene Names
stringlengths
2
299
⌀
Toxin
bool
2 classes
species
stringclasses
111 values
cdhit_cluster
int64
0
4.65k
cdhit_rep
stringlengths
5
10
cdhit_rep_is_ref
bool
1 class
cdhit_pct_id
float64
546,501
P9WHZ8
MILDFSWLPPEINSARIYAGAGSGPLFMAAAAWEGLAADLRASASSFDAVIAGLAAGPWSGPASVAMAGAAAPYVGWLSAAAGQAELSAGQATAAATAFEAALAATVHPAAVTANRVLLGALVATNILGQNTPAIAATEFDYVEMWAQDVGAMVGYHAGAAAVAETLTPFSVPPLDLAGLASQAGAQLTGMATSVSAALSPIAEGAVEGVPAVVAAAQSVAAGLPVDAALQVGQAAAYPASMLIGPMMQLAQMGTTANTAGLAGAEAAGLAAADVPTFAGDIASGTGLGGAGGLGAGMSAELGKARLVGAMSVPPTWEGSVPARMASSAMAGLGAMPAEVPAAGGPMGMMPMPMGMGGAGAGMPAGMMGRGGANPHVVQARPSVVPRVGIG
Uncharacterized PPE family protein PPE38
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
83,331
391
37,355
Reference proteome
GO:0052572
Inferred from homology
1
null
null
null
PF00823;PF12484;
IPR022171;IPR000030;IPR038332;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
PPE38 MT2419
false
Mycobacterium tuberculosis
730
row_526596
false
null
213,068
P9WP73
MVFRQAPVELPGLAPMPGQPFGVYLHVPFCLTRCGYCDFNTYTPAQLGGVSPDRWLLALRAELELAAAKLDAPTVHTVYVGGGTPSLLGGERLATLLDMVRDHFVLAPDAEVSTEANPESTWPEFFATIRAAGYTRVSLGMQSVAPRVLATLDRVHSPGRAAAAATEAIAEGFTHVNLDLIYGTPGESDDDLVRSVDAAVQAGVDHVSAYALVVEHGTALARRVRRGELAAPDDDVLAHRYELVDARLSAAGFAWYEVSNWCRPGGECRHNLGYWDGGQWWGAGPGAHGYIGVTRWWNVKHPNTYAEILAGATLPVAGFEQLGADALHTEDVLLKVRLRQGLPLARLGAAERERAEAVLADGLLDYHGDRLVLTGRGRLLADAVVRTLLG
Heme chaperone HemW (Oxygen-independent coproporphyrinogen-III oxidase-like protein Rv2388c)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
390
41,941
4Fe-4S;Chaperone;Cytoplasm;Direct protein sequencing;Heme;Iron;Iron-sulfur;Metal-binding;Reference proteome;S-adenosyl-L-methionine
GO:0004109; GO:0005737; GO:0006779; GO:0046872; GO:0051539
Evidence at protein level
3
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q9CGF7}.
null
null
PF04055;
IPR013785;IPR034505;IPR006638;IPR004559;IPR007197;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
hemW hemN Rv2388c MTCY253.33
false
Mycobacterium tuberculosis
731
row_199268
false
null
431,192
P9WGA8
MIIVVGIGADGMTGLSEHSRSELRRATVIYGSKRQLALLDDTVTAERWEWPTPMLPAVQGLSPDGADLHVVASGDPLLHGIGSTLIRLFGHDNVTVLPHVSAVTLACARMGWNVYDTEVISLVTAQPHTAVRRGGRAIVLSGDRSTPQALAVLLTEHGRGDSKFSVLEQLGGPAERRRDGTARAWACDPPLDVDELNVIAVRYLPDERTSWAPDEAFAHDGQITKHPIRVLTLAALAPRPGQRLWDVGAGSGAIAVQWCRSWPGCTAVAFERDERRRRNIGFNAAAFGVSVDVRGDAPDAFDDAARPSVIFLGGGVTQPGLLEACLHSLPAGGNLVANAVTVESEAALAHAYSRLGGELRRFQHYLGEPLGGFTGWRPQLPVTQWSVTKR
Precorrin-6Y C(5,15)-methyltransferase [decarboxylating] (Precorrin-6 methyltransferase) (Precorrin-6Y methylase) (EC 2.1.1.132)
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
83,331
390
41,860
Cobalamin biosynthesis;Methyltransferase;Reference proteome;S-adenosyl-L-methionine;Transferase
GO:0008276; GO:0009236; GO:0032259; GO:0046025
Inferred from homology
2
null
null
null
PF00590;
IPR000878;IPR035996;IPR014777;IPR012818;IPR006365;IPR014008;IPR050714;IPR029063;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
cobL MT2132
false
Mycobacterium tuberculosis
732
row_412951
false
null
213,013
P9WNS7
MSRRRAIQPSPALRIGPIELASPVVLAPMAGVTNVAFRALCRQLEQSKVGTVSGLYVCEMVTARALIERHPVTMHMTTFSADESPRSLQLYTVDPDTTYAAARMIAGEGLADHIDMNFGCPVPKVTKRGGGAALPFKRRLFGQIVAAAVRATEGTDIPVTVKFRIGIDDAHHTHLDAGRIAEAEGAAAVALHARTAAQRYSGTADWEQIARLKQHVRTIPVLGNGDIYDAGDALAMMSTTGCDGVVIGRGCLGRPWLFAELSAAFTGSPAPTPPTLGEVADIIRRHGTLLAAHFGEDKGMRDIRKHIAWYLHGFPAGSALRRALAMVKTFDELDCLLDRLDGTVPFPDSATGARGRQGSPARVALPDGWLTDPDDCRVPEGADAMGSGG
Probable tRNA-dihydrouridine synthase (EC 1.3.1.-)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
389
41,388
Flavoprotein;FMN;NADP;Oxidoreductase;Reference proteome;RNA-binding;tRNA processing;tRNA-binding
GO:0000049; GO:0017150; GO:0050660
Evidence at protein level
3
null
null
null
PF01207;
IPR013785;IPR035587;IPR001269;IPR004652;IPR024036;IPR018517;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
dus Rv0823c MTV043.15c
false
Mycobacterium tuberculosis
733
row_199214
false
null
425,331
P63428
MVGWAGNPSFDLFKLPEEHDEMRSAIRALAEKEIAPHAAEVDEKARFPEEALVALNSSGFNAVHIPEEYGGQGADSVATCIVIEEVARVDASASLIPAVNKLGTMGLILRGSEELKKQVLPALAAEGAMASYALSEREAGSDAASMRTRAKADGDHWILNGAKCWITNGGKSTWYTVMAVTDPDRGANGISAFMVHKDDEGFTVGPKERKLGIKGSPTTELYFENCRIPGDRIIGEPGTGFKTALATLDHTRPTIGAQAVGIAQGALDAAIAYTKDRKQFGESISTFQAVQFMLADMAMKVEAARLMVYSAAARAERGEPDLGFISAASKCFASDVAMEVTTDAVQLFGGAGYTTDFPVERFMRDAKITQIYEGTNQIQRVVMSRALLR
Probable acyl-CoA dehydrogenase fadE25 (EC 1.3.99.-)
Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
233,413
389
41,723
FAD;Flavoprotein;Oxidoreductase;Reference proteome
GO:0003995; GO:0050660
Inferred from homology
2
null
null
null
PF00441;PF02770;PF02771;
IPR006089;IPR006091;IPR046373;IPR036250;IPR009075;IPR013786;IPR037069;IPR009100;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype)
fadE25 acd BQ2027_MB3302C
false
Mycobacterium tuberculosis
734
row_407432
false
null
431,799
P9WL29
MIDPTARAWAYLSRVAEPPCAQLAALVRCVGPVEAADRVRRGQVGNELAQHTGARREIDRAADDLELLMRRGGRLITPDDDEWPVLAFAAFSGAGARARPCGHSPLVLWALGPARLDEVAPRAAAVVGTRAATAYGEHVAADLAAGLAERDVAVVSGGAYGIDGAAHRAALDSEGITVAVLAGGFDIPYPAGHSALLHRIAQHGVLFTEYPPGVRPARHRFLTRNRLVAAVARAAVVVEAGLRSGAANTAAWARALGRVVAAVPGPVTSSASAGCHTLLRHGAELVTRADDIVEFVGHIGELAGDEPRPGAALDVLSEAERQVYEALPGRGAATIDEIAVGSGLLPAQVLGPLAILEVAGLAECRDGRWRILRAGAGQAAAKGAAARLV
Putative DNA processing protein DprA
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
389
40,100
Reference proteome
GO:0009294
Evidence at protein level
2
null
null
null
PF02481;PF17782;
IPR003488;IPR041614;IPR036388;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
dprA Rv2896c MTCY274.27c
false
Mycobacterium tuberculosis
735
row_413554
false
null
26,731
P9WGB7
MSEDRTGHQGISGPATRAIHAGYRPDPATGAVNVPIYASSTFAQDGVGGLRGGFEYARTGNPTRAALEASLAAVEEGAFARAFSSGMAATDCALRAMLRPGDHVVIPDDAYGGTFRLIDKVFTRWDVQYTPVRLADLDAVGAAITPRTRLIWVETPTNPLLSIADITAIAELGTDRSAKVLVDNTFASPALQQPLRLGADVVLHSTTKYIGGHSDVVGGALVTNDEELDEEFAFLQNGAGAVPGPFDAYLTMRGLKTLVLRMQRHSENACAVAEFLADHPSVSSVLYPGLPSHPGHEIAARQMRGFGGMVSVRMRAGRRAAQDLCAKTRVFILAESLGGVESLIEHPSAMTHASTAGSQLEVPDDLVRLSVGIEDIADLLGDLEQALG
Cystathionine gamma-synthase (CGS) (EC 2.5.1.48) (O-succinylhomoserine (thiol)-lyase)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
388
40,982
Amino-acid biosynthesis;Cytoplasm;Methionine biosynthesis;Pyridoxal phosphate;Reference proteome;Transferase
GO:0003962; GO:0004123; GO:0005737; GO:0005829; GO:0005886; GO:0019279; GO:0019343; GO:0019346; GO:0030170
Evidence at protein level
5
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
null
null
PF01053;
IPR000277;IPR054542;IPR015424;IPR015421;IPR015422;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
metB Rv1079 MTV017.32
false
Mycobacterium tuberculosis
736
row_23378
false
null
26,746
P9WGJ9
MAGSATVEKRLDFGLLGPLQMTIDGTPVPSGTPKQRAVLAMLVINRNRPVGVDALITALWEEWPPSGARASIHSYVSNLRKLLGGAGIDPRVVLAAAPPGYRLSIPDNTCDLGRFVAEKTAGVHAAAAGRFEQASRHLSAALREWRGPVLDDLRDFQFVEPFATALVEDKVLAHTAKAEAEIACGRASAVIAELEALTFEHPYREPLWTQLITAYYLSDRQSDALGAYRRVKTTLADDLGIDPGPTLRALNERILRQQPLDAKKSAKTTAAGTVTVLDQRTMASGQQAVAYLHDIASGRGYPLQAAATRIGRLHDNDIVLDSANVSRHHAVIVDTGTNYVINDLRSSNGVHVQHERIRSAVTLNDGDHIRICDHEFTFQISAGTHGGT
Transcriptional regulatory protein EmbR
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
388
41,933
3D-structure;DNA-binding;Phosphoprotein;Reference proteome;Transcription;Transcription regulation;Two-component regulatory system
GO:0000160; GO:0003677; GO:0003924; GO:0005886; GO:0006355; GO:0009274; GO:0016887; GO:0045893
Evidence at protein level
5
null
null
null
PF03704;PF00498;PF00486;
IPR051677;IPR005158;IPR000253;IPR001867;IPR016032;IPR008984;IPR011990;IPR036388;
2FEZ;2FF4;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
embR Rv1267c MTCY50.15
false
Mycobacterium tuberculosis
737
row_23393
false
null
59,699
A0A0H3M1P5
MAFPRTLAILAAAAALVVACSHGGTPTGSSTTSGASPATPVAVPVPRSCAEPAGIPALLSPRDKLAQLLVVGVRDAADAQAVVTNYHVGGILIGSDTDLTIFDGALAEIVAGGGPLPLAVSVDEEGGRLSRLRSLIGGTGPSARELAQTRTVQQVRDLARDRGRQMRKLGITIDFAPVVDVTDAPDDTVIGDRSFGSDPATVTAYAGAYAQGLRDAGVLPVLKHFPGHGRGSGDSHNGGVTTPPLDDLVGDDLVPYRTLVTQAPVGVMVGHLQVPGLTGSEPASLSKAAVNLLRTGTGYGAPPFDGPVFSDDLSGMAAISDRFGVSEAVLRTLQAGADIALWVTTKEVPAVLDRLEQALRAGELPMSAVDRSVVRVATMKGPNPGCGR
Beta-hexosaminidase LpqI (EC 3.2.1.52) (Beta-N-acetylglucosaminidase) (Beta-N-acetylhexosaminidase)
Mycobacterium bovis (strain BCG / Pasteur 1173P2)
410,289
388
39,533
Cell inner membrane;Cell membrane;Glycosidase;Hydrolase;Lipoprotein;Membrane;Palmitate;Signal
GO:0004563; GO:0005886; GO:0005975; GO:0009254
Inferred from homology
4
SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250|UniProtKB:L7N6B0}; Lipid-anchor {ECO:0000255|PROSITE-ProRule:PRU00303}; Periplasmic side {ECO:0000250|UniProtKB:L7N6B0}.
SIGNAL 1..19; /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
null
PF00933;
IPR001764;IPR036962;IPR017853;IPR050226;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype), Mycobacterium tuberculosis variant bovis BCG (no rank)
lpqI BCG_0275
false
Mycobacterium tuberculosis
738
row_51645
false
null
212,002
P96847
MTDRVALRAGVPPFYVMDVWLAAAERQRTHGDLVNLSAGQPSAGAPEPVRAAAAAALHLNQLGYSVALGIPELRDAIAADYQRRHGITVEPDAVVITTGSSGGFLLAFLACFDAGDRVAMASPGYPCYRNILSALGCEVVEIPCGPQTRFQPTAQMLAEIDPPLRGVVVASPANPTGTVIPPEELAAIASWCDASDVRLISDEVYHGLVYQGAPQTSCAWQTSRNAVVVNSFSKYYAMTGWRLGWLLVPTVLRRAVDCLTGNFTICPPVLSQIAAVSAFTPEATAEADGNLASYAINRSLLLDGLRRIGIDRLAPTDGAFYVYADVSDFTSDSLAFCSKLLADTGVAIAPGIDFDTARGGSFVRISFAGPSGDIEEALRRIGSWLPSQ
Valine--pyruvate aminotransferase (EC 2.6.1.66) (Alanine--valine transaminase)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
388
41,081
3D-structure;Aminotransferase;Pyridoxal phosphate;Reference proteome;Transferase
GO:0006520; GO:0009042; GO:0009058; GO:0009274; GO:0030170
Evidence at protein level
3
null
null
null
PF00155;
IPR004839;IPR050596;IPR004838;IPR015424;IPR015421;
5YHV;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
aspB Rv3565
false
Mycobacterium tuberculosis
739
row_198236
false
null
212,834
P9WLG1
MKALRSSSRLSRWREWAAPLWVGCNFSAWMRLLIRNRFAVHHSRWHFAVLYTFLSMVNSCLGLWQKIVFGRRVAETVIADPPIFIVGHWRTGTTLLHELLVVDDRHTGPTGYECLAPHHFLLTEWFAPYVEFLVSKHRAMDNMDLSLHHPQEDEFVWCMQGLPSPYLTIAFPNRPPQYEEYLDLEQVAPRELEIWKRTLFRFVQQVYFRRRKTVILKNPTHSFRIKVLLEVFPQAKFIHIVRDPYVVYPSTIHLHKALYRIHGLQQPTFDGLDDKVVSTYVDLYRKLDEGRELVDPTRFYELRYEDLIGDPEGQLRRLYQHLGLGDFECYLPRLRQYLADHADYKTNSYQLTVEQRAIVDEHWGEIIDRYGYDRHTPEPARLRPAVGG
Omega-hydroxy-beta-dihydromenaquinone-9 sulfotransferase Stf3 (EC 2.8.2.40) (PAPS-dependent sulfotransferase Stf3)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
388
46,062
Reference proteome;Transferase
GO:0008146; GO:0046506
Evidence at protein level
3
null
null
null
PF13469;
IPR027417;IPR052736;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
stf3 Rv2267c MTCY339.43
false
Mycobacterium tuberculosis
740
row_199038
false
null
213,219
P9WQG3
MTDTSFIESEERQALRKAVASWVANYGHEYYLDKARKHEHTSELWAEAGKLGFLGVNLPEEYGGGGAGMYELSLVMEEMAAAGSALLLMVVSPAINGTIIAKFGTDDQKKRWLPGIADGSLTMAFAITEPDAGSNSHKITTTARRDGSDWIIKGQKVFISGIDQAQAVLVVGRSEEAKTGKLRPALFVVPTDAPGFSYTPIEMELVSPERQFQVFLDDVRLPADALVGAEDAAIAQLFAGLNPERIMGAASAVGMGRFALGRAVDYVKTRKVWSTPIGAHQGLAHPLAQCHIEVELAKLMTQKAATLYDHGDDFGAAEAANMAKYAAAEASSRAVDQAVQSMGGNGLTKEYGVAAMMTSARLARIAPISREMVLNFVAQTSLGLPRSY
Acyl-CoA dehydrogenase FadE12 (EC 1.3.99.-) (Medium chain acyl-CoA dehydrogenase) (MCADH)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
388
41,515
FAD;Flavoprotein;Oxidoreductase;Reference proteome
GO:0003995; GO:0005737; GO:0005886; GO:0033539; GO:0050660
Evidence at protein level
3
null
null
null
PF00441;PF02770;PF02771;
IPR050741;IPR006091;IPR046373;IPR036250;IPR009075;IPR013786;IPR037069;IPR009100;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
fadE12 Rv0972c MTCY10D7.02
false
Mycobacterium tuberculosis
741
row_199417
false
null
25,349
P71858
MFIDLTPEQRQLQAEIRQYFSNLISPDERTEMEKDRHGPAYRAVIRRMGRDGRLGVGWPKEFGGLGFGPIEQQIFVNEAHRADVPLPAVTLQTVGPTLQAHGSELQKKKFLPAILAGEAHFAIGYTEPEAGTDLASLRTTAVRDGDHYIVNGQKVFTTGAHDADYIWLACRTDPNAAKHKGISILIVDTKDPGYSWTPIILADGAHHTNATYYNDVRVPVDMLVGKENDGWRLITTQLNNERVMLGPAGRFASIYDRVHAWASVPGGNGVTPIDHDDVKRALGEIRAIWRINELLNWQVASAGEDINMADAAATKVFGTERVQRAGRLAEEIVGKYGNPAEPDTAELLRWLDAQTKRNLVITFGGGVNEVMREMIAASGLKVPRVPR
Acyl-CoA dehydrogenase FadE29 (ACAD) (EC 1.3.99.-) (3-oxo-23,24-bisnorchol-4-en-22-oyl-CoA dehydrogenase beta subunit) (3-oxo-4-pregnene-20-carboxyl-CoA dehydrogenase beta subunit)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
387
42,715
Cholesterol metabolism;FAD;Flavoprotein;Lipid degradation;Lipid metabolism;NAD;NADP;Oxidoreductase;Reference proteome;Steroid metabolism;Sterol metabolism;Virulence
GO:0006707; GO:0016627; GO:0033539; GO:0051701; GO:0071949
Evidence at protein level
5
null
null
null
PF00441;PF02770;PF02771;
IPR006091;IPR046373;IPR036250;IPR009075;IPR013786;IPR037069;IPR009100;IPR052161;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
fadE29 Rv3543c
false
Mycobacterium tuberculosis
742
row_22145
false
null
26,947
P9WMZ1
MRVAMLTREYPPEVYGGAGVHVTELVAYLRRLCAVDVHCMGAPRPGAFAYRPDPRLGSANAALSTLSADLVMANAASAATVVHSHTWYTALAGHLAAILYDIPHVLTAHSLEPLRPWKKEQLGGGYQVSTWVEQTAVLAANAVIAVSSAMRNDMLRVYPSLDPNLVHVIRNGIDTETWYPAGPARTGSVLAELGVDPNRPMAVFVGRITRQKGVVHLVTAAHRFRSDVQLVLCAGAADTPEVADEVRVAVAELARNRTGVFWIQDRLTIGQLREILSAATVFVCPSVYEPLGIVNLEAMACATAVVASDVGGIPEVVADGITGSLVHYDADDATGYQARLAEAVNALVADPATAERYGHAGRQRCIQEFSWAYIAEQTLDIYRKVCA
Alpha-maltose-1-phosphate synthase (M1P synthase) (EC 2.4.1.342) (ADP-alpha-D-glucose:alpha-D-glucose-1-phosphate 4-alpha-D-glucosyltransferase) (M1P-producing glucosyltransferase)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
387
41,533
Capsule biogenesis/degradation;Carbohydrate metabolism;Glycosyltransferase;Reference proteome;Transferase
GO:0005978; GO:0009250; GO:0016757; GO:0045227
Evidence at protein level
5
null
null
null
PF13439;PF00534;
IPR001296;IPR028098;IPR011875;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
glgM glgA Rv1212c
false
Mycobacterium tuberculosis
743
row_23587
false
null
81,676
P9WGC5
MDLFEYQAKELFAKHNVPSTPGRVTDTAEGAKAIATEIGRPVMVKAQVKIGGRGKAGGVKYAATPQDAYEHAKNILGLDIKGHIVKKLLVAEASDIAEEYYLSFLLDRANRTYLAMCSVEGGMEIEEVAATKPERLAKVPVNAVKGVDLDFARSIAEQGHLPAEVLDTAAVTIAKLWELFVAEDATLVEVNPLVRTPDHKILALDAKITLDGNADFRQPGHAEFEDRAATDPLELKAKEHDLNYVKLDGQVGIIGNGAGLVMSTLDVVAYAGEKHGGVKPANFLDIGGGASAEVMAAGLDVVLGDQQVKSVFVNVFGGITSCDAVATGIVKALGMLGDEANKPLVVRLDGNNVEEGRRILTEANHPLVTLVATMDEAADKAAELASA
Succinate--CoA ligase [ADP-forming] subunit beta (EC 6.2.1.5) (Succinyl-CoA synthetase subunit beta) (SCS-beta)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
387
40,926
ATP-binding;Ligase;Magnesium;Metal-binding;Nucleotide-binding;Reference proteome;Tricarboxylic acid cycle
GO:0000287; GO:0004775; GO:0004776; GO:0005524; GO:0005829; GO:0006099; GO:0006104; GO:0009274; GO:0042709
Evidence at protein level
4
null
null
null
PF08442;PF00549;
IPR011761;IPR013650;IPR013815;IPR017866;IPR005811;IPR005809;IPR016102;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
sucC Rv0951 MTCY10D7.23c
false
Mycobacterium tuberculosis
744
row_72125
false
null
112,247
A1KML3
MTVGLGMPQPPAPTLAPRRATRQLMVGNVGVGSDHPVSVQSMCTTKTHDVNSTLQQIAELTAAGCDIVRVACPRQEDADALAEIARHSQIPVVADIHFQPRYIFAAIDAGCAAVRVNPGNIKEFDGRVGEVAKAAGAAGIPIRIGVNAGSLDKRFMEKYGKATPEALVESALWEASLFEEHGFGDIKISVKHNDPVVMVAAYELLAARCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSRGIGDTIRVSLSAPPVEEVKVGNQVLESLNLRPRSLEIVSCPSCGRAQVDVYTLANEVTAGLDGLDVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVRGEVIKTVPEAQIVETLIEEAMRLAAEMGEQDPGATPSGSPIVTVS
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin) (EC 1.17.7.3) (1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase)
Mycobacterium bovis (strain BCG / Pasteur 1173P2)
410,289
387
40,482
4Fe-4S;Iron;Iron-sulfur;Isoprene biosynthesis;Metal-binding;Oxidoreductase
GO:0005506; GO:0016114; GO:0019288; GO:0046429; GO:0051539; GO:0141197
Inferred from homology
3
null
null
null
PF04551;
IPR011005;IPR016425;IPR004588;IPR045854;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype), Mycobacterium tuberculosis variant bovis BCG (no rank)
ispG BCG_2890c
false
Mycobacterium tuberculosis
745
row_100712
false
null
25,350
P71875
MSTDTSGVGVREIDAGALPTRYARGWHCLGVAKDYLEGKPHGVEAFGTKLVVFADSHGDLKVLDGYCRHMGGDLSEGTVKGDEVACPFHDWRWGGDGRCKLVPYARRTPRMARTRSWTTDVRSGLLFVWHDHEGNPPDPAVRIPEIPEAASDEWTDWRWNRILIEGSNCRDIIDNVTDMAHFFYIHFGLPTYFKNVFEGHIASQYLHNVGRPDVDDLGTSYGEAHLDSEASYFGPSFMINWLHNRYGNYKSESILINCHYPVTQNSFVLQWGVIVEKPKGMSEEMTDKLSRVFTEGVSKGFLQDVEIWKHKTRIDNPLLVEEDGAVYQLRRWYEQFYVDVADIKPEMVERFEIEVDTKRANEFWNAEVEKNLKSREVSDDVPAEQH
3-ketosteroid-9-alpha-monooxygenase, oxygenase component (3-ketosteroid-9-alpha-hydroxylase, oxygenase component) (KSH) (Androsta-1,4-diene-3,17-dione 9-alpha-hydroxylase) (EC 1.14.15.30) (Rieske-type oxygenase) (RO)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
386
44,268
2Fe-2S;3D-structure;Cholesterol metabolism;Iron;Iron-sulfur;Lipid degradation;Lipid metabolism;Metal-binding;Oxidoreductase;Reference proteome;Steroid metabolism;Sterol metabolism;Virulence
GO:0005506; GO:0006694; GO:0006707; GO:0036200; GO:0047086; GO:0051537; GO:0070207; GO:0070723
Evidence at protein level
5
null
null
null
PF19298;PF00355;
IPR050584;IPR045605;IPR017941;IPR036922;
2ZYL;4QCK;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
kshA Rv3526
false
Mycobacterium tuberculosis
746
row_22146
false
null
27,061
P9WQ87
MKAATQARIDDSPLAWLDAVQRQRHEAGLRRCLRPRPAVATELDLASNDYLGLSRHPAVIDGGVQALRIWGAGATGSRLVTGDTKLHQQFEAELAEFVGAAAGLLFSSGYTANLGAVVGLSGPGSLLVSDARSHASLVDACRLSRARVVVTPHRDVDAVDAALRSRDEQRAVVVTDSVFSADGSLAPVRELLEVCRRHGALLLVDEAHGLGVRGGGRGLLYELGLAGAPDVVMTTTLSKALGSQGGVVLGPTPVRAHLIDAARPFIFDTGLAPAAVGAARAALRVLQAEPWRPQAVLNHAGELARMCGVAAVPDSAMVSVILGEPESAVAAAAACLDAGVKVGCFRPPTVPAGTSRLRLTARASLNAGELELARRVLTDVLAVARR
8-amino-7-oxononanoate synthase 1 (AONS) (EC 2.3.1.47) (7-keto-8-amino-pelargonic acid synthase) (7-KAP synthase) (KAPA synthase) (8-amino-7-ketopelargonate synthase)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
386
40,028
Acyltransferase;Biotin biosynthesis;Pyridoxal phosphate;Reference proteome;Transferase
GO:0005886; GO:0008710; GO:0009102; GO:0009274; GO:0030170
Evidence at protein level
5
null
null
null
PF00155;
IPR001917;IPR004839;IPR050087;IPR015424;IPR015421;IPR015422;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
bioF1 Rv1569 MTCY336.34c
false
Mycobacterium tuberculosis
747
row_23699
false
null
67,570
I6Y3T7
MLSGQAAIVGIGATDFSKNSGRSELRLAAEAVLDALADAGLSPTDVDGLTTFTMDTNTEIAVARAAGIGELTFFSKIHYGGGAACATVQHAAMAVATGVADVVVAYRAFNERSGMRFGQVQTRLTENADSTGVDNSFSYPHGLSTPAAQVAMIARRYMHLSGATSRDFGAVSVADRKHAANNPKAYFYGKPITIEDHQNSRWIAEPLRLLDCCQETDGAVAIVVTSAARARDLKQRPVVIEAAAQGCSPDQYTMVSYYRPELDGLPEMGLVGRQLWAQSGLTPADVQTAVLYDHFTPFTLIQLEELGFCGKGEAKDFIADGAIEVGGRLPINTHGGQLGEAYIHGMNGIAEGVRQLRGTSVNPVAGVEHVLVTAGTGVPTSGLILG
17-hydroxy-3-oxo-4-pregnene-20-carboxyl-CoA lyase (EC 4.1.3.-) (Retro-aldolase Ltp2)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
386
40,588
Cholesterol metabolism;Lipid metabolism;Lyase;Reference proteome;Steroid metabolism;Sterol metabolism
GO:0006707; GO:0016746; GO:0016747; GO:0016829
Evidence at protein level
4
null
null
null
PF22691;PF00108;
IPR002155;IPR016039;IPR055140;IPR020616;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
ltp2 Rv3540c
false
Mycobacterium tuberculosis
748
row_58702
false
null
67,571
I6Y498
MSVTPKTLDMGAILADTSNRVVVCCGAGGVGKTTTAAALALRAAEYGRTVVVLTIDPAKRLAQALGINDLGNTPQRVPLAPEVPGELHAMMLDMRRTFDEMVMQYSGPERAQSILDNQFYQTVATSLAGTQEYMAMEKLGQLLSQDRWDLIVVDTPPSRNALDFLDAPKRLGSFMDSRLWRLLLAPGRGIGRLITGVMGLAMKALSTVLGSQMLADAAAFVQSLDATFGGFREKADRTYALLKRRGTQFVVVSAAEPDALREASFFVDRLSQESMPLAGLVFNRTHPMLCALPIERAIDAAETLDAETTDSDATSLAAAVLRIHAERGQTAKREIRLLSRFTGANPTVPVVGVPSLPFDVSDLEALRALADQLTTVGNDAGRAAGR
ATPase BagB (EC 3.6.1.-) (ATPase Rv3680) (Bacterial Get3-like protein B)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
386
41,405
3D-structure;ATP-binding;Hydrolase;Nucleotide-binding;Reference proteome
GO:0005524; GO:0016887
Evidence at protein level
4
null
null
null
PF02374;
IPR025723;IPR016300;IPR027417;
6BS3;6BS4;6BS5;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
bagB Rv3680
false
Mycobacterium tuberculosis
749
row_58703
false
null
69,183
O53637
MAILRGRAPLRLGLGGGGTDVEPYSSQFGGRILSVTIDKYAYAFAERGTGDEIAFRSPDRDRAGQASIDDLASLEEDFPLHVAVYRRVIAEFNGGTPFPLQLATQVDAPPGSGLGSSSALVVAMLLTTCALIGSSPGPYELARLAWEIERVDLGMAGGWQDHYAAAFGGFNFMESRPNGEVVVNPLRIRREVIAELEASLLLYFGGVSRLSSEVIADQQRNVVERDADALAATHSICAEALEMKDLLVVGDIPGFADSLLRGWQAKKRTSTRISNPAIEHAYQVAQSSGMVAGKVSGAGGGGFLMMIVDPRRRIEVARSLERECGGSVAPCLFTKGGAVTWHIPESTAPVRRGVADAVASALGNAGILLCAGCVLATSHSTWRVPV
D-glycero-alpha-D-manno-heptose 7-phosphate kinase (EC 2.7.1.168) (D-alpha-D-heptose 7-phosphate kinase) (MtbHddA)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
386
40,827
ATP-binding;Carbohydrate metabolism;Kinase;Lipopolysaccharide biosynthesis;Magnesium;Metal-binding;Nucleotide-binding;Reference proteome;Transferase
GO:0004335; GO:0005524; GO:0005829; GO:0006012; GO:0009103; GO:0046872
Evidence at protein level
4
null
null
null
PF08544;PF00288;
IPR052203;IPR013750;IPR036554;IPR006204;IPR001174;IPR014606;IPR020568;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
hddA Rv0115
false
Mycobacterium tuberculosis
750
row_60184
false
null
213,218
P9WQF9
MTAGSDLDDFRGLLAKAFDERVVAWTAEAEAQERFPRQLIEHLGVCGVFDAKWATDARPDVGKLVELAFALGQLASAGIGVGVSLHDSAIAILRRFGKSDYLRDICDQAIRGAAVLCIGASEESGGSDLQIVETEIRSRDGGFEVRGVKKFVSLSPIADHIMVVARSVDHDPTSRHGNVAVVAVPAAQVSVQTPYRKVGAGPLDTAAVCIDTWVPADALVARAGTGLAAISWGLAHERMSIAGQIAASCQRAIGITLARMMSRRQFGQTLFEHQALRLRMADLQARVDLLRYALHGIAEQGRLELRTAAAVKVTAARLGEEVISECMHIFGGAGYLVDETTLGKWWRDMKLARVGGGTDEVLWELVAAGMTPDHDGYAAVVGASKA
Acyl-[acyl-carrier-protein] dehydrogenase MbtN (Acyl-ACP dehydrogenase MbtN) (EC 1.3.99.-) (Mycobactin synthase protein N)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
386
41,180
3D-structure;FAD;Flavoprotein;Oxidoreductase;Reference proteome
GO:0003995; GO:0005737; GO:0019540; GO:0033539; GO:0050660; GO:0141148
Evidence at protein level
3
null
null
null
PF00441;PF02770;PF02771;
IPR050741;IPR006091;IPR046373;IPR036250;IPR009075;IPR013786;IPR037069;IPR009100;
4XVX;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
mbtN fadE14 Rv1346 MTCY02B10.10
false
Mycobacterium tuberculosis
751
row_199416
false
null
539,493
P0A5D4
MRIGVGVCTTPDARQAAVEAAGQARDELAGEAPSLAVLLGSRAHTDRAADVLSAVLQMIDPPALVGCIAQAIVAGRHEIEDEPAVVVWLASGLAAETFQLDFVRTGSGALITGYRFDRTARDLHLLLPDPYTFPSNLLIEHPNTDLPGTAVVGGVVSGGRRRGDTRLFRDHDVLTSGVVGVRLPGMRGVPVVSQGCRPIGYPYIVTGADGILITELGGRPPLQRLREIVEGLSPDERALVSHGLQIGIVVDEHLAAPGQGDFVIRGLLGADPSTGSIEIDEVVQVGATMQFQVRDAAGADKDLRLTVERAAARLPGRAAGALLFTCNGRGRRMFGVADHDASTIEELLGGIPLAGFFAAGEIGPIAGRNALHGFTASMALFVDDME
Uncharacterized protein Mb0898c
Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
233,413
386
40,402
Cell membrane;Membrane;Reference proteome;Transmembrane;Transmembrane helix
GO:0005886
Predicted
1
SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
null
TRANSMEM 54..74; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 347..367; /note="Helical"; /evidence="ECO:0000255"
PF08495;PF10442;
IPR019494;IPR013702;IPR016741;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype)
BQ2027_MB0898C
false
Mycobacterium tuberculosis
752
row_519782
false
null
81,853
P9WMZ3
MSRVLLVTNDFPPRRGGIQSYLGEFVGRLVGSRAHAMTVYAPQWKGADAFDDAARAAGYRVVRHPSTVMLPGPTVDVRMRRLIAEHDIETVWFGAAAPLALLAPRARLAGASRVLASTHGHEVGWSMLPVARSVLRRIGDGTDVVTFVSSYTRSRFASAFGPAASLEYLPPGVDTDRFRPDPAARAELRKRYRLGERPTVVCLSRLVPRKGQDTLVTALPSIRRRVDGAALVIVGGGPYLETLRKLAHDCGVADHVTFTGGVATDELPAHHALADVFAMPCRTRGAGMDVEGLGIVFLEASAAGVPVIAGNSGGAPETVQHNKTGLVVDGRSVDRVADAVAELLIDRDRAVAMGAAGREWVTAQWRWDTLAAKLADFLRGDDAAR
GDP-mannose-dependent alpha-(1-6)-phosphatidylinositol monomannoside mannosyltransferase (EC 2.4.1.346) (Alpha-D-mannose-alpha-(1-6)-phosphatidylmyo-inositol-mannosyltransferase) (Alpha-mannosyltransferase) (Alpha-ManT) (Guanosine diphosphomannose-phosphatidyl-inositol alpha-mannosyltransferase) (Phosphatidylinositol alpha-mannosyltransferase) (PI alpha-mannosyltransferase)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
385
41,220
Glycosyltransferase;Lipid biosynthesis;Lipid metabolism;Phospholipid biosynthesis;Phospholipid metabolism;Reference proteome;Transferase;Virulence
GO:0000030; GO:0005886; GO:0008654; GO:0009247; GO:0016757; GO:0033164; GO:0043750; GO:0046488
Evidence at protein level
4
null
null
null
PF13439;PF00534;
IPR001296;IPR028098;IPR050194;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
pimB Rv2188c
false
Mycobacterium tuberculosis
753
row_72297
false
null
181,640
I6Y3V5
MQDVEEFRAQVRGWLADNLAGEFAALKGLGGPGREHEAFEERRAWNQRLAAAGLTCLGWPEEHGGRGLSTAHRVAFYEEYARADAPDKVNHFGEELLGPTLIAFGTPQQQRRFLPRIRDVTELWCQGYSEPGAGSDLASVATTAELDGDQWVINGQKVWTSLAHLSQWCFVLARTEKGSQRHAGLSYLLVPLDQPGVQIRPIVQITGTAEFNEVFFDDARTDADLVVGAPGDGWRVAMATLTFERGVSTLGQQIVYARELSNLVELARRTAAADDPLIRERLTRAWTGLRAMRSYALATMEGPAVEQPGQDNVSKLLWANWHRNLGELAMDVIGKPGMTMPDGEFDEWQRLYLFTRADTIYGGSNEIQRNIIAERVLGLPREAKG
Acyl-CoA dehydrogenase IpdE1 (EC 1.3.99.-) (5OH-HIP-CoA dehydrogenase alpha subunit)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
385
42,732
Cholesterol metabolism;FAD;Flavoprotein;Lipid metabolism;Oxidoreductase;Reference proteome;Steroid metabolism;Sterol metabolism
GO:0006707; GO:0016627; GO:0050660
Evidence at protein level
3
null
null
null
PF00441;PF02770;PF02771;
IPR006091;IPR046373;IPR036250;IPR009075;IPR013786;IPR037069;IPR009100;IPR052161;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
ipdE1 fadE30 Rv3560c
false
Mycobacterium tuberculosis
754
row_168686
false
null
207,218
P63410
MSSTVLVINSGSSSLKFQLVEPVAGMSRAAGIVERIGERSSPVADHAQALHRAFKMLAEDGIDLQTCGLVAVGHRVVHGGTEFHQPTLLDDTVIGKLEELSALAPLHNPPAVLGIKVARRLLANVAHVAVFDTAFFHDLPPAAATYAIDRDVADRWHIRRYGFHGTSHQYVSERAAAFLGRPLDGLNQIVLHLGNGASASAIARGRPVETSMGLTPLEGLVMGTRSGDLDPGVISYLWRTARMGVEDIESMLNHRSGMLGLAGERDFRRLRLVIETGDRSAQLAYEVFIHRLRKYLGAYLAVLGHTDVVSFTAGIGENDAAVRRDALAGLQGLGIALDQDRNLGPGHGARRISSDDSPIAVLVVPTNEELAIARDCLRVLGGRRA
Acetate kinase (EC 2.7.2.1) (Acetokinase)
Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
233,413
385
41,318
ATP-binding;Cytoplasm;Kinase;Magnesium;Metal-binding;Nucleotide-binding;Reference proteome;Transferase
GO:0000287; GO:0005524; GO:0005737; GO:0006083; GO:0006085; GO:0008776
Inferred from homology
3
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00020}.
null
null
PF00871;
IPR004372;IPR000890;IPR023865;IPR043129;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype)
ackA BQ2027_MB0417
false
Mycobacterium tuberculosis
755
row_193641
false
null
212,512
P9WHI9
MYVRHLGLRDFRSWACVDLELHPGRTVFVGPNGYGKTNLIEALWYSTTLGSHRVSADLPLIRVGTDRAVISTIVVNDGRECAVDLEIATGRVNKARLNRSSVRSTRDVVGVLRAVLFAPEDLGLVRGDPADRRRYLDDLAIVRRPAIAAVRAEYERVLRQRTALLKSVPGARYRGDRGVFDTLEVWDSRLAEHGAELVAARIDLVNQLAPEVKKAYQLLAPESRSASIGYRASMDVTGPSEQSDIDRQLLAARLLAALAARRDAELERGVCLVGPHRDDLILRLGDQPAKGFASHGEAWSLAVALRLAAYQLLRVDGGEPVLLLDDVFAELDVMRRRALATAAESAEQVLVTAAVLEDIPAGWDARRVHIDVRADDTGSMSVVLP
DNA replication and repair protein RecF
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
385
42,212
ATP-binding;Cytoplasm;DNA damage;DNA repair;DNA replication;DNA-binding;Nucleotide-binding;Reference proteome;SOS response
GO:0000731; GO:0003697; GO:0005524; GO:0005829; GO:0005886; GO:0006260; GO:0006302; GO:0009432
Evidence at protein level
3
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
null
null
PF02463;
IPR001238;IPR018078;IPR027417;IPR003395;IPR042174;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
recF Rv0003 MTCY10H4.01
false
Mycobacterium tuberculosis
756
row_198720
false
null
426,959
P67474
MRLDQRWLIARVIMRSAIGFFASFTVSSGVLAANVLADPADDALAKLNELSRQAEQTTEALHSAQLDLNEKLAAQRAADQKLADNRTALDAARARLATFQTAVNKVAAATYMGGRTHGMDAILTAESPQLLIDRLSVQRVMAHQMSTQMARFKAAGEQAVKAEQAAAKSAADARSAAEQAAAVRANLQHKQSQLQVQIAVVKSQYVALTPEERTALADPGPVPAVAAIAPGAPPAALPPGAPPGDGPAPGVAPPPGGMPGLPFVQPDGAGGDRTAVVQAALTQVGAPYAWGGAAPGGFDCSGLVMWAFQQAGIALPHSSQALAHGGQPVALSDLQPGDVLTFYSDASHAGIYIGDGLMVHSSTYGVPVRVVPMDSSGPIYDARRY
Probable endopeptidase Mb2213c (EC 3.4.-.-)
Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
233,413
385
39,756
Hydrolase;Protease;Reference proteome;Thiol protease
GO:0006508; GO:0008234
Inferred from homology
2
null
null
null
PF00877;
IPR000064;IPR038765;IPR051794;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype)
BQ2027_MB2213C
false
Mycobacterium tuberculosis
757
row_409053
false
null
546,446
P9WFM2
MNTEFTLTQKRALAILTLIALLFGAYFLRNYFVLIVVAAVGAYLFTPLFKWFTKRFNTGLSAACTLLSALAAVVVPVGALVGLAIVQIARMVDSVADWVRTTDLSTLGDKILQFVNGLFDRVPFLHITVTADALRKAMISVAQNVGEWLLHFLRDAAGSLAGVITSAIIFVYVFVALLVNREKLRTLIGQLNPLGEDVTDLYLQKMGSMVRGTVNGQFVIAACQGVAGAASIYIAGFHHGFFIFAIVLTALSIIPLGGGIVTIPFGIGMIFYGNIAGGIFVLLWHLLVVTNIDNVLRPILVPRDARLNSALMLLSVFAGITMFGPWGIIIGPVLMILIVTTIDVYLAVYKGVELEQFEAPPVRRRWLPRRGPATSRNAPPPSTAE
Putative transport protein MT1133
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
83,331
385
41,717
Cell membrane;Membrane;Reference proteome;Transmembrane;Transmembrane helix;Transport
GO:0005886
Inferred from homology
1
SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
null
TRANSMEM 7..27; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 32..52; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 66..86; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 159..179; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 218..238; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 241..261; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 263..283; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 319..339; /note="Helical"; /evidence="ECO:0000255"
PF01594;
IPR002549;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
MT1133
false
Mycobacterium tuberculosis
758
row_526541
false
null
546,515
P9WI18
MDFGALPPEVNSGRMYCGPGSAPMVAAASAWNGLAAELSVAAVGYERVITTLQTEEWLGPASTLMVEAVAPYVAWMRATAIQAEQAASQARAAAAAYETAFAAIVPPPLIAANRARLTSLVTHNVFGQNTASIAATEAQYAEMWAQDAMAMYGYAGSSATATKVTPFAPPPNTTSPSAAATQLSAVAKAAGTSAGAAQSAIAELIAHLPNTLLGLTSPLSSALTAAATPGWLEWFINWYLPISQLFYNTVGLPYFAIGIGNSLITSWRALGWIGPEAAEAAAAAPAAVGAAVGGTGPVSAGLGNAATIGKLSLPPNWAGASPSLAPTVGSASAPLVSDIVEQPEAGAAGNLLGGMPLAGSGTGMGGAGPRYGFRVTVMSRPPFAG
Uncharacterized PPE family protein PPE22
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
83,331
385
38,474
Reference proteome
GO:0052572
Inferred from homology
1
null
null
null
PF00823;PF12484;
IPR022171;IPR000030;IPR038332;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
PPE22 MT1745
false
Mycobacterium tuberculosis
759
row_526608
false
null
27,062
P9WQA9
MTPISQTPGLLAEAMVDLGAIEHNVRVLREHAGHAQLMAVVKADGYGHGATRVAQTALGAGAAELGVATVDEALALRADGITAPVLAWLHPPGIDFGPALLADVQVAVSSLRQLDELLHAVRRTGRTATVTVKVDTGLNRNGVGPAQFPAMLTALRQAMAEDAVRLRGLMSHMVYADKPDDSINDVQAQRFTAFLAQAREQGVRFEVAHLSNSSATMARPDLTFDLVRPGIAVYGLSPVPALGDMGLVPAMTVKCAVALVKSIRAGEGVSYGHTWIAPRDTNLALLPIGYADGVFRSLGGRLEVLINGRRCPGVGRICMDQFMVDLGPGPLDVAEGDEAILFGPGIRGEPTAQDWADLVGTIHYEVVTSPRGRITRTYREAENR
Alanine racemase (EC 5.1.1.1)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
384
40,724
3D-structure;Isomerase;Pyridoxal phosphate;Reference proteome
GO:0005829; GO:0008784; GO:0009252; GO:0030170; GO:0030632
Evidence at protein level
5
null
null
null
PF00842;PF01168;
IPR000821;IPR009006;IPR011079;IPR001608;IPR020622;IPR029066;
1XFC;6SCZ;8AHW;8B8H;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
alr Rv3423c MTCY78.06
false
Mycobacterium tuberculosis
760
row_23700
false
null
181,639
I6Y3P1
MNRIWLRAIILTASSALLAGCQFGGLNSLPLPGTAGHGEGAYSVTVEMADVATLPQNSPVMVDDVTVGSVAGIVAVQRPDGSFYAAVKLDLDKNVLLPANAVAKVSQTSLLGSLHVELAPPTDRPPTGRLVDGSRITEANTDRFPTTEEVFSALGVVVNKGNVGALEEIIDETHQAVAGRQAQFVNLVPRLAELTAGLNRQVHDIIDALDGLNRVSAILARDKDNLGRALDTLPDAVRVLNQNRDHIVDAFAALKRLTMVTSHVLAETKVDFGEDLKDLYSIVKALNDDRKDFVTSLQLLLTFPFPNFGIKQAVRGDYLNVFTTFDLTLRRIGETFFTTAYFDPNMAHMDEILNPPDFLIGELANLSGQAADPFKIPPGTASGQ
Lipoprotein LprN
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
384
41,293
Cell membrane;Lipoprotein;Membrane;Palmitate;Reference proteome;Signal;Virulence
GO:0005886; GO:0009274; GO:0044409; GO:0120010; GO:0120014
Evidence at protein level
3
SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|PROSITE-ProRule:PRU00303}; Lipid-anchor {ECO:0000255|PROSITE-ProRule:PRU00303}.
SIGNAL 1..20; /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
null
PF02470;
IPR005693;IPR003399;IPR052336;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
lprN mce4E Rv3495c
false
Mycobacterium tuberculosis
761
row_168685
false
null
403,124
O07737
MRAVVIDGAGSVRVNTQPDPALPGPDGVVVAVTAAGICGSDLHFYEGEYPFTEPVALGHEAVGTIVEAGPQVRTVGVGDLVMVSSVAGCGVCPGCETHDPVMCFSGPMIFGAGVLGGAQADLLAVPAADFQVLKIPEGITTEQALLLTDNLATGWAAAQRADISFGSAVAVIGLGAVGLCALRSAFIHGAATVFAVDRVKGRLQRAATWGATPIPSPAAETILAATRGRGADSVIDAVGTDASMSDALNAVRPGGTVSVVGVHDLQPFPVPALTCLLRSITLRMTMAPVQRTWPELIPLLQSGRLDVDGIFTTTLPLDEAAKGYATARARSGEELRFCLRPDSRDVLGAHETVDLYVHVRRCQSVADLQLEGAADGVDGPSMLN
Probable zinc-binding alcohol dehydrogenase Rv1895 (EC 1.1.1.1)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
384
39,479
Metal-binding;NAD;Oxidoreductase;Reference proteome;Zinc
GO:0004022; GO:0008270
Evidence at protein level
2
null
null
null
PF08240;PF00107;
IPR013149;IPR013154;IPR002328;IPR011032;IPR036291;IPR020843;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
Rv1895
false
Mycobacterium tuberculosis
762
row_385656
false
null
213,181
P9WQ38
MRALHVPAGSATALLLPALQRVLGGSDPALVAVPTQHESLLGALRVGEQIDDDVALVVTTSGTTGPPKGAMLTAAALTASASAAHDRLGGPGSWLLAVPPYHIAGLAVLVRSVIAGSVPVELNVSAGFDVTELPNAIKRLGSGRRYTSLVAAQLAKALTDPAATAALAELDAVLIGGGPAPRPILDAAAAAGITVVRTYGMSETSGGCVYDGVPLDGVRLRVLAGGRIAIGGATLAKGYRNPVSPDPFAEPGWFHTDDLGALESGDSGVLTVLGRADEAISTGGFTVLPQPVEAALGTHPAVRDCAVFGLADDRLGQRVVAAIVVGDGCPPPTLEALRAHVARTLDVTAAPRELHVVNVLPRRGIGKVDRAALVRRFAGEADQ
Probable 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA synthetase) (o-succinylbenzoyl-CoA synthetase)
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
83,331
383
38,755
ATP-binding;Ligase;Menaquinone biosynthesis;Nucleotide-binding;Reference proteome
GO:0005524; GO:0008756; GO:0009234
Inferred from homology
3
null
null
null
PF00501;PF13193;
IPR025110;IPR045851;IPR020845;IPR000873;IPR042099;IPR050237;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
menE MT0567
false
Mycobacterium tuberculosis
763
row_199379
false
null
544,649
P64730
MRIGVGVSTAPDVRRAAAEAAAHAREELAGGTPALAVLLGSRSHTDQAVDLLAAVQASVEPAALIGCVAQGIVAGRHELENEPAVAVWLASGPPAETFHLDFVRTGSGALITGYRFDRTAHDLHLLLPDPYSFPSNLLIEHLNTDLPGTTVVGGVVSGGRRRGDTRLFRDRDVLTSGLVGVRLPGAHSVSVVSQGCRPIGEPYIVTGADGAVITELGGRPPLHRLREIVLGMAPDEQELVSRGLQIGIVVDEHLAVPGQGDFLIRGLLGADPTTGAIGIGEVVEVGATVQFQVRDAAAADKDLRLAVERAAAELPGPPVGGLLFTCNGRGRRMFGVTDHDASTIEDLLGGIPLAGFFAAGEIGPVAGHNALHGFTASMALFVD
Uncharacterized protein Mb0644c
Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
233,413
383
39,606
Cell membrane;Membrane;Reference proteome;Transmembrane;Transmembrane helix
GO:0005886
Predicted
1
SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
null
TRANSMEM 49..69; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 347..367; /note="Helical"; /evidence="ECO:0000255"
PF08495;PF10442;
IPR019494;IPR013702;IPR016741;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype)
BQ2027_MB0644C
false
Mycobacterium tuberculosis
764
row_524892
false
null
81,889
P9WNV7
MARDYYGLLGVSKNASDADIKRAYRKLARELHPDVNPDEAAQAKFKEISVAYEVLSDPDKRRIVDLGGDPLESAAAGGNGFGGFGGLGDVFEAFFGGGFGGGAASRGPIGRVRPGSDSLLRMRLDLEECATGVTKQVTVDTAVLCDRCQGKGTNGDSVPIPCDTCGGRGEVQTVQRSLLGQMLTSRPCPTCRGVGVVIPDPCQQCMGDGRIRARREISVKIPAGVGDGMRVRLAAQGEVGPGGGPAGDLYVEVHEQAHDVFVREGDHLHCTVSVPMVDAALGVTVTVDAILDGLSEITIPPGTQPGSVITLRGRGMPHLRSNTRGDLHVHVEVVVPTRLDHQDIELLRELKGRRDREVAEVRSTHAAAGGLFSRLRETFTGR
Chaperone protein DnaJ 2
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
382
40,489
Chaperone;Cytoplasm;DNA replication;Metal-binding;Reference proteome;Repeat;Stress response;Zinc;Zinc-finger
GO:0005524; GO:0005737; GO:0006260; GO:0008270; GO:0009274; GO:0009408; GO:0031072; GO:0042026; GO:0051082; GO:0051085
Evidence at protein level
4
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01152}.
null
null
PF00226;PF01556;PF00684;
IPR012724;IPR002939;IPR001623;IPR008971;IPR001305;IPR036410;IPR036869;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
dnaJ2 Rv2373c MTCY27.07
false
Mycobacterium tuberculosis
765
row_72329
false
null
410,019
P0A685
MQFLSVIPEQVESAAQDLAGIRSALSASYAAAAGPTTAVVSAAEDEVSTAIASIFGAYGRQCQVLSAQASAFHDEFVNLLKTGATAYRNTEFANAQSNVLNAVNAPARSLLGHPSAAESVQNSAPTLGGGHSTVTAGLAAQAGRAVATVEQQAAAAVAPLPSAGAGLAQVVNGVVTAGQGSAAKLATALQSAAPWLAKSGGEFIVAGQSALTGVALLQPAVVGVVQAGGTFLTAGTSAATGLGLLTLAGVEFSQGVGNLALASGTAATGLGLLGSAGVQLFSPAFLLAVPTALGGVGSLAIAVVQLVQGVQHLSLVVPNVVAGIAALQTAGAQFAQGVNHTMLAAQLGAPGIAVLQTAGGHFAQGIGHLTTAGNAAVTVLIS
Uncharacterized PE family protein PE23
Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
233,413
382
36,833
Cell membrane;Membrane;Reference proteome;Transmembrane;Transmembrane helix
GO:0005886
Inferred from homology
2
SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
null
TRANSMEM 23..43; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 155..175; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 203..223; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 230..250; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 261..281; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 284..304; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 315..335; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 347..367; /note="Helical"; /evidence="ECO:0000255"
PF00934;
IPR000084;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype)
PE23 BQ2027_MB2355
false
Mycobacterium tuberculosis
766
row_392475
false
null
431,450
P9WHZ2
MDFGALPPEVNSARMYGGAGAADLLAAAAAWNGIAVEVSTAASSVGSVITRLSTEHWMGPASLSMAAAVQPYLVWLTCTAESSALAAAQAMASAAAFETAFALTVPPAEVVANRALLAELTATNILGQNVSAIAATEARYGEMWAQDASAMYGYAAASAVAARLNPLTRPSHITNPAGLAHQAAAVGQAGASAFARQVGLSHLISDVADAVLSFASPVMSAADTGLEAVRQFLNLDVPLFVESAFHGLGGVADFATAAIGNMTLLADAMGTVGGAAPGGGAAAAVAHAVAPAGVGGTALTADLGNASVVGRLSVPASWSTAAPATAAGAALDGTGWAVPEEDGPIAVMPPAPGMVVAANSVGADSGPRYGVKPIVMPKHGLF
PPE family protein PPE44
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
83,331
382
37,467
Cell wall;Reference proteome;Secreted;Virulence
GO:0009986; GO:0052572
Inferred from homology
2
SUBCELLULAR LOCATION: Secreted, cell wall {ECO:0000250|UniProtKB:P9WHZ3}. Cell surface {ECO:0000250|UniProtKB:P9WHZ3}.
null
null
PF00823;PF12484;
IPR022171;IPR000030;IPR038332;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
PPE44 MT2840
false
Mycobacterium tuberculosis
767
row_413209
false
null
72,748
P0CF99
MRVVQVANFYGPRSGGLRTAVDRLGAEYCASGHEVFLIVPGARTERHLLRTGVVRITLPAKHIPYTGGYRAVMPGAVRTVLETLRPDALEVSDRLTLRSLGRWGREHGVTTVMISHERLDRFAGQLLPRRAAQKFADFANARTAANYDTVVCTTGFAREEFDRIGATNTVTVPLGVDLKTFHPRRRCARVRQHWATPTQILLVHCGRLSVEKHADRSIDALAALCDAGVDARLVIAGEGPLRARLERKATGLPIDFTGFISDRHAVAGLLASADVALAPGPHETFGLAALESLACGTPAVVSRTSALTEIITADSGACADNRPEAIAHAVRTIVSRPERHRRRCARRRAEIFTWQRAAASMLATLGAMAVSTRCGDTQDTA
GDP-mannose-dependent alpha-(1-6)-phosphatidylinositol dimannoside mannosyltransferase (EC 2.4.1.-) (Alpha-D-mannose-alpha-(1-6)-phosphatidylmyo-inositol-mannosyltransferase) (Guanosine diphosphomannose-phosphatidyl-inositol alpha-mannosyltransferase) (Phosphatidylinositol alpha-mannosyltransferase) (PI alpha-mannosyltransferase)
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
83,331
381
41,289
Glycosyltransferase;Lipid biosynthesis;Lipid metabolism;Phospholipid biosynthesis;Phospholipid metabolism;Reference proteome;Transferase;Virulence
GO:0009247; GO:0016020; GO:0033164; GO:0043750; GO:0046474; GO:0046488; GO:0047264
Evidence at protein level
4
null
null
null
PF13579;PF00534;
IPR001296;IPR028098;IPR050194;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
pimC RvD2-ORF1 MT1800
false
Mycobacterium tuberculosis
768
row_63623
false
null
212,719
P9WJN7
MSGTRDGDLNAAIRTALGKVIDPELRRPITELGMVKSIDTGPDGSVHVEIYLTIAGCPKKSEITERVTRAVADVPGTSAVRVSLDVMSDEQRTELRKQLRGDTREPVIPFAQPDSLTRVYAVASGKGGVGKSTVTVNLAAAMAVRGLSIGVLDADIHGHSIPRMMGTTDRPTQVESMILPPIAHQVKVISIAQFTQGNTPVVWRGPMLHRALQQFLADVYWGDLDVLLLDLPPGTGDVAISVAQLIPNAELLVVTTPQLAAAEVAERAGSIALQTRQRIVGVVENMSGLTLPDGTTMQVFGEGGGRLVAERLSRAVGADVPLLGQIPLDPALVAAGDSGVPLVLSSPDSAIGKELHSIADGLSTRRRGLAGMSLGLDPTRR
Iron-sulfur cluster carrier protein
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
381
40,084
ATP-binding;Hydrolase;Iron;Iron-sulfur;Metal-binding;Nucleotide-binding;Reference proteome
GO:0005524; GO:0016226; GO:0016887; GO:0046872; GO:0051539; GO:0140663
Evidence at protein level
3
null
null
null
PF01883;PF10609;
IPR034904;IPR002744;IPR000808;IPR019591;IPR044304;IPR027417;IPR033756;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
mrp Rv1229c MTCI61.12c MTV006.01c
false
Mycobacterium tuberculosis
769
row_198925
false
null
321,148
A1KMU5
MGGLRFGFVDALVHSRLPPTLPARSSMAAATVMGADSYWVGDHLNALVPRSIATSEYLGIAAKFVPKIDANYEPWTMLGNLAFGLPSRLRLGVCVTDAGRRNPAVTAQAAATLHLLTRGRAILGIGVGEREGNEPYGVEWTKPVARFEEALATIRALWNSNGELISRESPYFPLHNALFDLPPYRGKWPEIWVAAHGPRMLRATGRYADAWIPIVVVRPSDYSRALEAVRSAASDAGRDPMSITPAAVRGIITGRNRDDVEEALESVVVKMTALGVPGEAWARHGVEHPMGADFSGVQDIIPQTMDKQTVLSYAAKVPAALMKEVVFSGTPDEVIDQVAEWRDHGLRYVVLINGSLVNPSLRKTVTAVLPHAKVLRGLKKL
Phthiodiolone/phenolphthiodiolone dimycocerosates ketoreductase (EC 1.2.-.-)
Mycobacterium bovis (strain BCG / Pasteur 1173P2)
410,289
381
41,348
Lipid biosynthesis;Lipid metabolism;Oxidoreductase
GO:0006629; GO:0016705
Inferred from homology
2
null
null
null
PF00296;
IPR050564;IPR011251;IPR036661;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype), Mycobacterium tuberculosis variant bovis BCG (no rank)
BCG_2972c
false
Mycobacterium tuberculosis
770
row_304520
false
null
431,934
P9WMT7
MKGSQASDDATGSLGPGRLQLPAMRVLVAPDCYGDSLSAVEAAAAIATGWTRSRPGDSFIVAPQSDGGPGFVEVLGSRLGETRRLRVCGPLNTVVNAAWVFDPGSATAYLECAQACGLGLLGGPPTPETALAAHSKGVGQLIAAALRAGAARIVVGLGGSACTDGGKGMIAELGGLDAARRQLADVEVIAASDVEYPLLGPWGTARVFAPQKGADMATVAVLEGRLAAWAIELDAAAGRGVSAEPGAGAAGGIGAGLLAVGGRYQSGAAIIAEHTHFADDLADAELIVTGEGRFDEQSLHGKVVGAIAAAARPLAIPVIVLAGQVSLDKSALRSAGIMAALSIAEYAGSVRLALADAANQLMGLASQVAARLGNSGPSGYR
Uncharacterized protein Rv2205c
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
381
37,832
Kinase;Reference proteome;Transferase
GO:0008887; GO:0009274; GO:0031388; GO:0043798
Evidence at protein level
2
null
null
null
PF02595;
IPR018193;IPR004381;IPR018197;IPR036129;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
Rv2205c MTCY190.16c
false
Mycobacterium tuberculosis
771
row_413689
false
null
432,171
P9WPR9
MQGAVAGLVFLAVLVIFAIIVVAKSVALIPQAEAAVIERLGRYSRTVSGQLTLLVPFIDRVRARVDLRERVVSFPPQPVITEDNLTLNIDTVVYFQVTVPQAAVYEISNYIVGVEQLTTTTLRNVVGGMTLEQTLTSRDQINAQLRGVLDEATGRWGLRVARVELRSIDPPPSIQASMEKQMKADREKRAMILTAEGTREAAIKQAEGQKQAQILAAEGAKQAAILAAEADRQSRMLRAQGERAAAYLQAQGQAKAIEKTFAAIKAGRPTPEMLAYQYLQTLPEMARGDANKVWVVPSDFNAALQGFTRLLGKPGEDGVFRFEPSPVEDQPKHAADGDDAEVAGWFSTDTDPSIARAVATAEAIARKPVEGSLGTPPRLTQ
Uncharacterized protein Rv1488
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
381
41,282
Membrane;Reference proteome;Transmembrane;Transmembrane helix
GO:0005576; GO:0005886; GO:0009274
Evidence at protein level
2
SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
null
TRANSMEM 3..23; /note="Helical"; /evidence="ECO:0000255"
PF01145;
IPR050710;IPR001107;IPR036013;IPR018080;IPR001972;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
Rv1488 MTCY277.09
false
Mycobacterium tuberculosis
772
row_413916
false
null
538,574
O69659
MGAGPVIPTRLATVRRRRPWRGVLLTLAAVAVVASIGTYLTAPRPGGAMAPASTSSTGGHALATLLGNHGVEVVVADSIADVEAAARPDSLLLVAQTQYLVDNALLDRLAKAPGDLLLVAPTSRTRTALTPQLRIAAASPFNSQPNCTLREANRAGSVQWGPSDTYQATGDLVLTSCYGGALVRFRAEGRTITVVGSSNFMTNGGLLPAGNAALAMNLAGNRPRLVWYAPDHIEGEMSSPSSLSDLIPENVHWTIWQLWLVVLLVALWKGRRIGPLVAEELPVVIRASETVEGRGRLYRSRRARDRAADALRTATLQRLRPRLGVGAGAPAPAVVTTIAQRSKADPPFVAYHLFGPAPATDNDLLQLARALDDIERQVTHS
Uncharacterized membrane protein Rv3691
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
381
40,442
Cell membrane;Membrane;Reference proteome;Transmembrane;Transmembrane helix
GO:0005886
Evidence at protein level
1
SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
null
TRANSMEM 22..42; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 246..266; /note="Helical"; /evidence="ECO:0000255"
PF14258;
IPR025646;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
Rv3691
false
Mycobacterium tuberculosis
773
row_518874
false
null
26,801
P9WHY3
MDFALLPPEVNSARMYTGPGAGSLLAAAGGWDSLAAELATTAEAYGSVLSGLAALHWRGPAAESMAVTAAPYIGWLYTTAEKTQQTAIQARAAALAFEQAYAMTLPPPVVAANRIQLLALIATNFFGQNTAAIAATEAQYAEMWAQDAAAMYGYATASAAAALLTPFSPPRQTTNPAGLTAQAAAVSQATDPLSLLIETVTQALQALTIPSFIPEDFTFLDAIFAGYATVGVTQDVESFVAGTIGAESNLGLLNVGDENPAEVTPGDFGIGELVSATSPGGGVSASGAGGAASVGNTVLASVGRANSIGQLSVPPSWAAPSTRPVSALSPAGLTTLPGTDVAEHGMPGVPGVPVAAGRASGVLPRYGVRLTVMAHPPAAG
Transporter PPE51 (Proline-proline-glutamate family protein 51) (PPE family protein 51) (Protein PPE51)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
380
37,980
Acetylation;Cell outer membrane;Membrane;Reference proteome;Transport;Virulence
GO:0009274; GO:0009279; GO:0015155; GO:0015168; GO:0015254; GO:0015267; GO:0015574; GO:0015767; GO:0015771; GO:0015793; GO:0035821; GO:0042594; GO:0042783; GO:0052572; GO:0055056; GO:0071466; GO:0140321; GO:1904659; GO:1904981
Evidence at protein level
5
SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000269|PubMed:32139546, ECO:0000305|PubMed:35136132}.
null
null
PF00823;PF12484;
IPR022171;IPR000030;IPR038332;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
PPE51 Rv3136
false
Mycobacterium tuberculosis
774
row_23447
false
null
26,931
P9WML7
MTRSGHPVTLDDLPLRADLRGKAPYGAPQLAVPVRLNTNENPHPPTRALVDDVVRSVREAAIDLHRYPDRDAVALRADLAGYLTAQTGIQLGVENIWAANGSNEILQQLLQAFGGPGRSAIGFVPSYSMHPIISDGTHTEWIEASRANDFGLDVDVAVAAVVDRKPDVVFIASPNNPSGQSVSLPDLCKLLDVAPGIAIVDEAYGEFSSQPSAVSLVEEYPSKLVVTRTMSKAFAFAGGRLGYLIATPAVIDAMLLVRLPYHLSSVTQAAARAALRHSDDTLSSVAALIAERERVTTSLNDMGFRVIPSDANFVLFGEFADAPAAWRRYLEAGILIRDVGIPGYLRATTGLAEENDAFLRASARIATDLVPVTRSPVGAP
Histidinol-phosphate aminotransferase (HspAT) (EC 2.6.1.9) (Imidazole acetol-phosphate transaminase)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
380
40,581
3D-structure;Amino-acid biosynthesis;Aminotransferase;Histidine biosynthesis;Pyridoxal phosphate;Reference proteome;Transferase
GO:0000105; GO:0004400; GO:0005886; GO:0009274; GO:0030170
Evidence at protein level
5
null
null
null
PF00155;
IPR001917;IPR004839;IPR005861;IPR015424;IPR015421;IPR015422;
4R8D;4RAE;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
hisC hisC1 Rv1600 MTCY336.04c
false
Mycobacterium tuberculosis
775
row_23572
false
null
81,870
P9WNE9
MSKKHTTLNASIIDTRRPTVAGADRHPGWHALRKIAARITTPLLPDDYLHLANPLWSARELRGRILGVRRETEDSATLFIKPGWGFSFDYQPGQYIGIGLLVDGRWRWRSYSLTSSPAASGSARMVTVTVKAMPEGFLSTHLVAGVKPGTIVRLAAPQGNFVLPDPAPPLILFLTAGSGITPVMSMLRTLVRRNQITDVVHLHSAPTAADVMFGAELAALAADHPGYRLSVRETRAQGRLDLTRIGQQVPDWRERQTWACGPEGVLNQADKVWSSAGASDRLHLERFAVSKTAPAGAGGTVTFARSGKSVAADAATSLMDAGEGAGVQLPFGCRMGICQSCVVDLVEGHVRDLRTGQRHEPGTRVQTCVSAASGDCVLDI
NADPH oxidoreductase (EC 1.-.-.-) (Stearoyl-CoA 9-desaturase electron transfer partner)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
380
40,795
2Fe-2S;Cell membrane;Electron transport;FAD;Flavoprotein;Iron;Iron-sulfur;Membrane;Metal-binding;NAD;Oxidoreductase;Reference proteome;Transport
GO:0005886; GO:0006631; GO:0009055; GO:0016491; GO:0022900; GO:0046872; GO:0051537; GO:0070402
Evidence at protein level
4
SUBCELLULAR LOCATION: Cell membrane; Peripheral membrane protein; Cytoplasmic side {ECO:0000305|PubMed:17087501}.
null
null
PF00970;PF00111;PF00175;
IPR036010;IPR001041;IPR012675;IPR008333;IPR017927;IPR001709;IPR039261;IPR050415;IPR001433;IPR017938;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
Rv3230c
false
Mycobacterium tuberculosis
776
row_72313
false
null
431,870
P9WM79
MAGNPDVVTVLLGGDVMLGRGVDQILPHPGKPQLRERYMRDATGYVRLAERVNGRIPLPVDWRWPWGEALAVLENTATDVCLINLETTITADGEFADRKPVCYRMHPDNVPALTALRPHVCALANNHILDFGYQGLTDTVAALAGAGIQSVGAGADLLAARRSALVTVGHERRVIVGSVAAESSGVPESWAARRDRPGVWLIRDPAQRDVADDVAAQVLADKRPGDIAIVSMHWGSNWGYATAPGDVAFAHRLIDAGIDMVHGHSSHHPRPIEIYRGKPILYGCGDVVDDYEGIGGHESFRSELRLLYLTVTDPASGNLISLQMLPLRVSRMRLQRASQTDTEWLRNTIERISRRFGIRVVTRPDNLLEVVPAANLTSKE
Probable polyglutamine synthesis accessory protein Rv0574c
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
380
41,547
Reference proteome;Stress response
null
Evidence at protein level
2
null
null
null
PF09587;
IPR019079;IPR052169;IPR029052;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
Rv0574c
false
Mycobacterium tuberculosis
777
row_413625
false
null
546,899
P9WLK0
MPVSDDSSSAFDLICAEIERQLRGGELLMDAAAASELLLTVRYQLDTQPRPLVIVHGPLFQAVKAARAQVYGRLIQLRHARCEVLDERWQLRPTGQRDVRALLIDVLNVLLAAITAAGVERAYACAERRAMAAAVVAKNYRDALGVELQCNSVCRAAAEAIHALAHRTGATEDADCLPPVDVIHADVTRRMHGEVATDVVAAGELVIAARHLLDPMPRGELSYGPLHEGGNAARKSVYRRLVQLWQARRAVTDGDVDLRDARTLLTDLDSILREMRTAATIQQSGTAGDGGGGRRQDSRRRNGPRRPARRGTSRGRRCAPRVAIGWHTPIGDPLAVEGVEEIGASLPGRESTPSDDGGSLHPSGRPRRVHRRRWCGLGLC
Uncharacterized protein MT2146
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
83,331
380
41,314
Reference proteome
null
Predicted
1
null
null
null
null
null
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
MT2146
false
Mycobacterium tuberculosis
778
row_526991
false
null
26,961
P9WN95
MTPPHNYLAVIKVVGIGGGGVNAVNRMIEQGLKGVEFIAINTDAQALLMSDADVKLDVGRDSTRGLGAGADPEVGRKAAEDAKDEIEELLRGADMVFVTAGEGGGTGTGGAPVVASIARKLGALTVGVVTRPFSFEGKRRSNQAENGIAALRESCDTLIVIPNDRLLQMGDAAVSLMDAFRSADEVLLNGVQGITDLITTPGLINVDFADVKGIMSGAGTALMGIGSARGEGRSLKAAEIAINSPLLEASMEGAQGVLMSIAGGSDLGLFEINEAASLVQDAAHPDANIIFGTVIDDSLGDEVRVTVIAAGFDVSGPGRKPVMGETGGAHRIESAKAGKLTSTLFEPVDAVSVPLHTNGATLSIGGDDDDVDVPPFMRR
Cell division protein FtsZ
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
379
38,756
3D-structure;Cell cycle;Cell division;Cytoplasm;GTP-binding;Nucleotide-binding;Reference proteome;Septation
GO:0000287; GO:0000917; GO:0000921; GO:0003924; GO:0005525; GO:0005737; GO:0005886; GO:0032153; GO:0043093; GO:0045787; GO:0051258; GO:0051301
Evidence at protein level
5
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00909}. Note=Assembles at midcell at the inner surface of the cytoplasmic membrane. {ECO:0000255|HAMAP-Rule:MF_00909}.
null
null
PF12327;PF00091;
IPR000158;IPR020805;IPR045061;IPR024757;IPR008280;IPR037103;IPR018316;IPR036525;IPR003008;
1RLU;1RQ2;1RQ7;2Q1X;2Q1Y;4KWE;5V68;5ZUE;6Y1U;6Y1V;6YM1;6YM9;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
ftsZ Rv2150c MTCY270.18
false
Mycobacterium tuberculosis
779
row_23601
false
null
112,271
A1KP32
MTISDVPTQTLPAEGEIGLIDVGSLQLESGAVIDDVCIAVQRWGKLSPARDNVVVVLHALTGDSHITGPAGPGHPTPGWWDGVAGPGAPIDTTRWCAVATNVLGGCRGSTGPSSLARDGKPWGSRFPLISIRDQVQADVAALAALGITEVAAVVGGSMGGARALEWVVGYPDRVRAGLLLAVGARATADQIGTQTTQIAAIKADPDWQSGDYHETGRAPDAGLRLARRFAHLTYRGEIELDTRFANHNQGNEDPTAGGRYAVQSYLEHQGDKLLSRFDAGSYVILTEALNSHDVGRGRGGVSAALRACPVPVVVGGITSDRLYPLRLQQELADLLPGCAGLRVVESVYGHDGFLVETEAVGELIRQTLGLADREGACRR
Homoserine O-acetyltransferase (HAT) (EC 2.3.1.31) (Homoserine transacetylase) (HTA)
Mycobacterium bovis (strain BCG / Pasteur 1173P2)
410,289
379
39,769
Acyltransferase;Amino-acid biosynthesis;Cytoplasm;Methionine biosynthesis;Transferase
GO:0004414; GO:0005737; GO:0009086; GO:0009092
Inferred from homology
3
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00296}.
null
null
PF00561;
IPR000073;IPR029058;IPR008220;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype), Mycobacterium tuberculosis variant bovis BCG (no rank)
metXA BCG_3411
false
Mycobacterium tuberculosis
780
row_100736
false
null
410,011
P0A657
MSVRLADVIDVLDQAYPPRLAQSWDSVGLVCGDPDDVVDSVTVAVDATPAVVDQVPQAGLLLVHHPLLLRGVDTVAANTPKGVLVHRLIRTGRSLFTAHTNADSASPGVSDALAHAVGLTVDAVLDPVPGAADLDKWVIYVPRENSEAVRAAVFEAGAGHIGDYSHCSWSVAGTGQFLAHDGASPAIGSVGTVERVAEDRVEVVAPARARAEVLAAMRAAHPYEEPAFDIFALVPPPVGSGLGRIGRLPKPEPLRTFVARLEAALPPTATGVRAAGDPDLLVSRVAVCGGAGDSLLATVAAADVQAYVTADLRHHPADEHCRASQVALIDVAHWASEFPWCGQAAEVLRSHFGASLPVRVCTICTDPWNLDHETGRDQA
GTP cyclohydrolase 1 type 2 homolog
Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
233,413
379
39,598
Metal-binding;Reference proteome
GO:0005737; GO:0046872
Inferred from homology
2
null
null
null
PF01784;
IPR002678;IPR017221;IPR036069;IPR015867;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype)
BQ2027_MB2255C
false
Mycobacterium tuberculosis
781
row_392467
false
null
26,948
P9WMZ5
MRIGMICPYSFDVPGGVQSHVLQLAEVMRTRGHLVSVLAPASPHAALPDYFVSGGRAVPIPYNGSVARLRFGPATHRKVKKWLAHGDFDVLHLHEPNAPSLSMLALNIAEGPIVATFHTSTTKSLTLTVFQGILRPMHEKIVGRIAVSDLARRWQMEALGSDAVEIPNGVDVDSFASAARLDGYPRQGKTVLFLGRYDEPRKGMAVLLDALPKVVQRFPDVQLLIVGHGDADQLRGQAGRLAAHLRFLGQVDDAGKASAMRSADVYCAPNTGGESFGIVLVEAMAAGTAVVASDLDAFRRVLRDGEVGHLVPVDPPDLQAAALADGLIAVLENDVLRERYVAAGNAAVRRYDWSVVASQIMRVYETVAGSGAKVQVAS
Phosphatidyl-myo-inositol mannosyltransferase (EC 2.4.1.345) (Alpha-mannosyltransferase) (GDP-mannose-dependent alpha-(1-2)-phosphatidylinositol mannosyltransferase) (Guanosine diphosphomannose-phosphatidyl-inositol alpha-mannosyltransferase) (Phosphatidylinositol alpha-mannosyltransferase) (PI alpha-mannosyltransferase)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
378
40,445
Cell membrane;Glycosyltransferase;Lipid biosynthesis;Lipid metabolism;Magnesium;Membrane;Phospholipid biosynthesis;Phospholipid metabolism;Reference proteome;Transferase;Virulence
GO:0000030; GO:0000287; GO:0004377; GO:0005886; GO:0008654; GO:0009247; GO:0016757; GO:0043750; GO:0046488
Evidence at protein level
5
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:A0QWG6}; Peripheral membrane protein {ECO:0000250|UniProtKB:A0QWG6}; Cytoplasmic side {ECO:0000250|UniProtKB:A0QWG6}.
null
null
PF13692;PF13439;
IPR028098;IPR050194;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
pimA Rv2610c MTCY01A10.23
false
Mycobacterium tuberculosis
782
row_23588
false
null
207,016
P62588
MTRVFHPALSGPEQSRYQITDVASVSRSGLCINESPIRDRCGRTMGDLRLSVIDQCNLRCRYCMPEAEYAWLPRADLLSVDEISLIVDAFIAVGVDKIRLTGGEPLIRSDLAAIIEVISAKVGDGSGLQDLAITTNGVLLADQARKLKSAGMRRITISLDTLRPDRFKAISQRGTHYKVIEGIEAVAAAGFTDTKLDSVVIRGFNDDELSDLIEFARNVNAEVRFIEYMDVGGATQWSMDKVFTKAQMLSTLGKKYGPIAALPKYDSAPANRYRLPDGTTFGIIASTTEPFCATCDRSRLTADGIWLHCLYALSGINLRESVRAGASANDVVQILQRGWRDRANRGAEQRLAQRTRQVFLPVSRLKRDPHLEMHTRGG
GTP 3',8-cyclase 3 (EC 4.1.99.22) (Molybdenum cofactor biosynthesis protein A 3)
Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
233,413
378
41,721
4Fe-4S;GTP-binding;Iron;Iron-sulfur;Lyase;Metal-binding;Molybdenum cofactor biosynthesis;Nucleotide-binding;Reference proteome;S-adenosyl-L-methionine
GO:0005525; GO:0006777; GO:0046872; GO:0051539; GO:0061798; GO:0061799; GO:1904047
Inferred from homology
3
null
null
null
PF06463;PF04055;
IPR013785;IPR006638;IPR013483;IPR000385;IPR010505;IPR050105;IPR007197;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype)
moaA3 BQ2027_MB3355C
false
Mycobacterium tuberculosis
783
row_193442
false
null
212,588
P9WI99
MANEPAIGAIDRLQRSSRDVTTLPAVISRWLSSVLPGGAAPEVTVESGVDSTGMSSETIILTARWQQDGRSIQQKLVARVAPAAEDVPVFPTYRLDHQFEVIRLVGELTDVPVPRVRWIETTGDVLGTPFFLMDYVEGVVPPDVMPYTFGDNWFADAPAERQRQLQDATVAALATLHSIPNAQNTFSFLTQGRTSDTTLHRHFNWVRSWYDFAVEGIGRSPLLERTFEWLQSHWPDDAAAREPVLLWGDARVGNVLYRDFQPVAVLDWEMVALGPRELDVAWMIFAHRVFQELAGLATLPGLPEVMREDDVRATYQALTGVELGDLHWFYVYSGVMWACVFMRTGARRVHFGEIEKPDDVESLFYHAGLMKHLLGEEH
Putative aminoglycoside phosphotransferase (EC 2.7.1.-) (Putative aminoglycoside antibiotics resistance enzyme)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
378
42,561
3D-structure;Antibiotic resistance;ATP-binding;Kinase;Magnesium;Metal-binding;Nucleotide-binding;Reference proteome;Transferase
GO:0005524; GO:0016301; GO:0046677; GO:0046872
Evidence at protein level
3
null
null
null
PF01636;
IPR041726;IPR051678;IPR002575;IPR011009;
3ATS;3ATT;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
Rv3168
false
Mycobacterium tuberculosis
784
row_198796
false
null
212,906
P9WMY5
MCGVRVAIVAESFLPQVNGVSNSVVKVLEHLRRTGHEALVIAPDTPPGEDRAERLHDGVRVHRVPSRMFPKVTTLPLGVPTFRMLRALRGFDPDVVHLASPALLGYGGLHAARRLGVPTVAVYQTDVPGFASSYGIPMTARAAWAWFRHLHRLADRTLAPSTATMESLIAQGIPRVHRWARGVDVQRFAPSARNEVLRRRWSPDGKPIVGFVGRLAPEKHVDRLTGLAASGAVRLVIVGDGIDRARLQSAMPTAVFTGARYGKELAEAYASMDVFVHSGEHETFCQVVQEALASGLPVIAPDAGGPRDLITPHRTGLLLPVGEFEHRLPDAVAHLVHERQRYALAARRSVLGRSWPVVCDELLGHYEAVRGRRTTQAA
GDP-mannose-dependent alpha-mannosyltransferase (EC 2.4.1.-) (Guanosine diphosphomannose-dependent alpha-mannosyltransferase)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
378
41,238
Glycosyltransferase;Lipid biosynthesis;Lipid metabolism;Phospholipid biosynthesis;Phospholipid metabolism;Reference proteome;Transferase;Virulence
GO:0000030; GO:0008654; GO:0009247; GO:0016020; GO:0016758; GO:0046488
Evidence at protein level
3
null
null
null
PF13439;PF00534;
IPR001296;IPR028098;IPR050194;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
mgtA pimB Rv0557
false
Mycobacterium tuberculosis
785
row_199109
false
null
431,938
P9WMU6
MYDSLDFDALEAAGIANPRERAGLLTYLDELGFTVEEMVQAERRGRLFGLAGDVLLWSGPPIYTLATAADELGLSADDVARAWSLLGLTVAGPDVPTLSQADVDALATWVALKALVGEDGAFGLLRVLGTAMARLAEAESTMIRAGSPNIQMTHTHDELATARAYRAAAEFVPRIGALIDTVHRHHLASARTYFEGVIGDTSASVTCGIGFADLSSFTALTQALTPAQLQDLLTEFDAAVTDVVHADGGRLVKFIGDAVMWVSSSPERLVRAAVDLVDHPGARAAELQVRAGLAYGTVLALNGDYFGNPVNLAARLVAAAAPGQILAAAQLRDMLPDWPALAHGPLTLKGFDAPVMAFELHDNPRARDADTPSPAASD
Uncharacterized protein MT2268
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
83,331
378
39,775
Reference proteome
GO:0004016; GO:0009190; GO:0035556
Inferred from homology
2
null
null
null
PF00211;
IPR001054;IPR050697;IPR029787;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
MT2268
false
Mycobacterium tuberculosis
786
row_413693
false
null
94,034
Q79FN7
MTSAGGFPAGAGGYQTPGGHSASPAHEAPPGGAEGLAAEVHTLERAIFEVKRIIVGQDQLVERMLVGLLSKGHVLLEGVPGVAKTLAVETFARVVGGTFSRIQFTPDLVPTDIIGTRIYRQGREEFDTELGPVVANFLLADEINRAPAKVQSALLEVMQERHVSIGGRTFPMPSPFLVMATQNPIEHEGVYPLPEAQRDRFLFKINVGYPSPEEEREIIYRMGVTPPQAKQILSTGDLLRLQEIAANNFVHHALVDYVVRVVFATRKPEQLGMNDVKSWVAFGASPRASLGIIAAARSLALVRGRDYVIPQDVIEVIPDVLRHRLVLTYDALADEISPEIVINRVLQTVALPQVNAVPQQGHSVPPVMQAAAAASGR
Chaperone MoxR1
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
377
40,763
ATP-binding;Chaperone;Nucleotide-binding;Reference proteome;Virulence
GO:0005524; GO:0005886; GO:0009274; GO:0016887
Evidence at protein level
4
null
null
null
PF07726;PF17863;
IPR011703;IPR050764;IPR041628;IPR027417;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
moxR1 moxR Rv1479
false
Mycobacterium tuberculosis
787
row_83530
false
null
495,901
Q7D9K1
MAHPMATHPRLQRRHGARSGSSRCRHRRPVPRRRSRSRPRWRAARAHRRHHRRSGPGIGDHPADRARHRRGGRLPAQPRRAAARRPDPRGGANTDHHAAPRHRRAAAGTSHRRRDRLASNDSQHHAHPTATGPRPRTTVRRRRQPRITHPVGTADHRTRTALRRPRPADQLSAALRSALEETRRLSGLADQLLTLARADRPESHPSAKAVPITPLLHESVARFAATGADITTRAEPDLFVSIDPDHLRRILTAVLDNAITHGDGEIAVTAHARDGAVDIGVRDHGPGFADHFLPVAFDRFTRADTARGGRGSGLGLAIVAALTTTHGGHANATNHPDGGAELRITLPTPRPPFHEELPRITSSDTKDPNREHDTSDQ
Probable sensor histidine kinase HK (EC 2.7.13.3)
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
83,331
377
41,547
ATP-binding;Kinase;Nucleotide-binding;Phosphoprotein;Reference proteome;Transferase;Two-component regulatory system
GO:0000160; GO:0004673; GO:0005524
Inferred from homology
2
null
null
null
PF02518;
IPR050980;IPR036890;IPR005467;IPR004358;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
MT0630
false
Mycobacterium tuberculosis
788
row_476683
false
null
26,352
P95125
MTKSLPGVADLRLGANHPRMWTRRVQGTVVNVGVKVLPWIPTPAKRILSAGRSVIIDGNTLDPTLQLMLSTSRIFGVDGLAVDDDIVASRAHMRAICEAMPGPQIHVDVTDLSIPGPAGEIPARHYRPSGGGATPLLVFYHGGGWTLGDLDTHDALCRLTCRDADIQVLSIDYRLAPEHPAPAAVEDAYAAFVWAHEHASDEFGALPGRVAVGGDSAGGNLSAVVCQLARDKARYEGGPTPVLQWLLYPRTDFTAQTRSMGLFGNGFLLTKRDIDWFHTQYLRDSDVDPADPRLSPLLAESLSGLAPALIAVAGFDPLRDEGESYAKALRAAGTAVDLRYLGSLTHGFLNLFQLGGGSAAGTNELISALRAHLSRV
Carboxylic ester hydrolase LipN (EC 3.1.1.-)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
376
40,135
Cytoplasm;Hydrolase;Reference proteome
GO:0005737; GO:0005886; GO:0008126; GO:0034338; GO:0106435
Evidence at protein level
5
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:26212120}.
null
null
PF07859;
IPR013094;IPR029058;IPR050300;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
lipN Rv2970c
false
Mycobacterium tuberculosis
789
row_23067
false
null
27,057
P9WQ73
MADQLTPHLEIPTAIKPRDGRFGSGPSKVRLEQLQTLTTTAAALFGTSHRQAPVKNLVGRVRSGLAELFSLPDGYEVILGNGGATAFWDAAAFGLIDKRSLHLTYGEFSAKFASAVSKNPFVGEPIIITSDPGSAPEPQTDPSVDVIAWAHNETSTGVAVAVRRPEGSDDALVVIDATSGAGGLPVDIAETDAYYFAPQKNFASDGGLWLAIMSPAALSRIEAIAATGRWVPDFLSLPIAVENSLKNQTYNTPAIATLALLAEQIDWLVGNGGLDWAVKRTADSSQRLYSWAQERPYTTPFVTDPGLRSQVVGTIDFVDDVDAGTVAKILRANGIVDTEPYRKLGRNQLRVAMFPAVEPDDVSALTECVDWVVERL
Phosphoserine aminotransferase (EC 2.6.1.52) (Phosphohydroxythreonine aminotransferase) (PSAT)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
376
40,233
3D-structure;Acetylation;Amino-acid biosynthesis;Aminotransferase;Cytoplasm;Direct protein sequencing;Pyridoxal phosphate;Pyridoxine biosynthesis;Reference proteome;Serine biosynthesis;Transferase
GO:0004648; GO:0004760; GO:0005576; GO:0005737; GO:0005886; GO:0006564; GO:0008453; GO:0008615; GO:0019265; GO:0030170
Evidence at protein level
5
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
null
null
PF00266;
IPR000192;IPR022278;IPR006272;IPR015424;IPR015421;IPR015422;
2FYF;3VOM;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
serC Rv0884c MTCY31.12c
false
Mycobacterium tuberculosis
790
row_23695
false
null
81,920
P9WPK4
MSKAVLVLEDGRVFTGRPFGATGQALGEAVFSTGMSGYQETLTDPSYHRQIVVATAPQIGNTGWNGEDSESRGERIWVAGYAVRDPSPRASNWRATGTLEDELIRQRIVGIAGIDTRAVVRHLRSRGSMKAGVFSDGALAEPADLIARVRAQQSMLGADLAGEVSTAEPYVVEPDGPPGVSRFTVAALDLGIKTNTPRNFARRGIRCHVLPASTTFEQIAELNPHGVFLSNGPGDPATADHVVALTREVLGAGIPLFGICFGNQILGRALGLSTYKMVFGHRGINIPVVDHATGRVAVTAQNHGFALQGEAGQSFATPFGPAVVSHTCANDGVVEGVKLVDGRAFSVQYHPEAAAGPHDAEYLFDQFVELMAGEGR
Carbamoyl phosphate synthase small chain (EC 6.3.5.5) (Carbamoyl phosphate synthetase glutamine chain)
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
83,331
376
39,767
Amino-acid biosynthesis;Arginine biosynthesis;ATP-binding;Glutamine amidotransferase;Ligase;Nucleotide-binding;Pyrimidine biosynthesis;Reference proteome
GO:0004088; GO:0004359; GO:0005524; GO:0006207; GO:0006526; GO:0006541; GO:0044205
Inferred from homology
4
null
null
null
PF00988;PF00117;
IPR050472;IPR006274;IPR002474;IPR036480;IPR029062;IPR035686;IPR017926;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
carA MT1427
false
Mycobacterium tuberculosis
791
row_72358
false
null
112,217
A1KLD5
MRSPHRDAIRTARGLVVKVGTTALTTPSGMFDAGRLAGLAEAVERRMKAGSDVVIVSSGAIAAGIEPLGLSRRPKDLATKQAAASVGQVALVNSWSAAFARYGRTVGQVLLTAHDISMRVQHTNAQRTLDRLRALHAVAIVNENDTVATNEIRFGDNDRLSALVAHLVGADALVLLSDIDGLYDCDPRKTADATFIPEVSGPADLDGVVAGRSSHLGTGGMASKVSAALLAADAGVPVLLAPAADAATALADASVGTVFAARPARLSARRFWVRYAAEATGALTLDAGAVRAVVRQRRSLLAAGITAVSGRFCGGDVVELRAPDAAMVARGVVAYDASELATMVGRSTSELPGELRRPVVHADDLVAVSAKQAKQV
Glutamate 5-kinase (EC 2.7.2.11) (Gamma-glutamyl kinase) (GK)
Mycobacterium bovis (strain BCG / Pasteur 1173P2)
410,289
376
38,804
Amino-acid biosynthesis;ATP-binding;Cytoplasm;Kinase;Nucleotide-binding;Proline biosynthesis;Transferase
GO:0003723; GO:0004349; GO:0005524; GO:0005829; GO:0055129
Inferred from homology
3
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00456}.
null
null
PF00696;PF01472;
IPR036393;IPR001048;IPR041739;IPR001057;IPR011529;IPR005715;IPR019797;IPR002478;IPR015947;IPR036974;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype), Mycobacterium tuberculosis variant bovis BCG (no rank)
proB BCG_2459c
false
Mycobacterium tuberculosis
792
row_100682
false
null
321,005
A1KFQ5
MPARRSAARIDFAGSPRPTLGVEWEFALVDSQTRDLSNEATAVIAEIGENPRVHKELLRNTVEIVSGICECTAEAMQDLRDTLGPARQIVRDRGMELFCAGTHPFARWSAQKLTDAPRYAELIKRTQWWGRQMLIWGVHVHVGIRSAHKVMPIMTSLLNYYPHLLALSASSPWWGGEDTGYASNRAMMFQQLPTAGLPFHFQRWAEFEGFVYDQKKTGIIDHMDEIRWDIRPSPHLGTLEVRICDGVSNLRELGALVALTHCLIVDLDRRLDAGETLPTMPPWHVQENKWRAARYGLDAVIILDADSNERLVTDDLADVLTRLEPVAKSLNCADELAAVSDIYRDGASYQRQLRVAQQHDGDLRAVVDALVAELVI
Putative glutamate--cysteine ligase 2 (EC 6.3.2.2) (Gamma-glutamylcysteine synthetase 2) (GCS 2) (Gamma-GCS 2)
Mycobacterium bovis (strain BCG / Pasteur 1173P2)
410,289
376
42,295
ATP-binding;Ligase;Nucleotide-binding
GO:0004357; GO:0005524; GO:0042398
Inferred from homology
2
null
null
null
PF04107;
IPR050141;IPR006336;IPR014746;IPR011793;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype), Mycobacterium tuberculosis variant bovis BCG (no rank)
BCG_0472
false
Mycobacterium tuberculosis
793
row_304377
false
null
431,780
P9WKT3
MSSSNGRGGAGGVGGSSEHPQYPKVVLVTGACRFLGGYLTARLAQNPLINRVIAVDAIAPSKDMLRRMGRAEFVRADIRNPFIAKVIRNGEVDTVVHAAAASYAPRSGGSAALKELNVMGAMQLFAACQKAPSVRRVVLKSTSEVYGSSPHDPVMFTEDSSSRRPFSQGFPKDSLDIEGYVRALGRRRPDIAVTILRLANMIGPAMDTTLSRYLAGPLVPTIFGRDARLQLLHEQDALGALERAAMAGKAGTFNIGADGILMLSQAIRRAGRIPVPVPGFGVWALDSLRRANHYTELNREQFAYLSYGRVMDTTRMRVELGYQPKWTTVEAFDDYFRGRGLTPIIDPHRVRSWEGRAVGLAQRWGSRNPIPWSGLR
Uncharacterized protein Rv0501
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
376
41,064
Reference proteome
GO:0005576; GO:0005829; GO:0005886
Evidence at protein level
2
null
null
null
PF01370;
IPR001509;IPR050177;IPR036291;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
Rv0501 MTCY20G9.28
false
Mycobacterium tuberculosis
794
row_413535
false
null
81,777
P9WJF5
MNTYLKPFELTLRCLGPVFIGSGEKRTSKEYHVEGDRVYFPDMELLYADIPAHKRKSFEAFVMNTDGAQATAPLKEWVEPNAVKLDPAKHRGYEVKIGSIEPRRASRGRGGRMTRKKLTLNEIHAFIKDPLGRPYVPGSTVKGMLRSIYLQSLVHKRTAQPVRVPGHQTREHRQYGERFERKELRKSGRPNTRPQDAVNDLFQAIRVTDSPALRTSDLLICQKMDMNVHGKPDGLPLFRECLAPGTSISHRVVVDTSPTARGGWREGERFLETLAETAASVNQARYAEYRAMYPGVNAIVGPIVYLGGGAGYRSKTFVTDQDDMAKVLDAQFGKVVKHVDKTRELRVSPLVLKRTKIDNICYEMGQCELSIRRAE
CRISPR system Cms protein Csm5 (CRISPR type III A-associated protein Csm5)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
375
42,340
3D-structure;Antiviral defense;Reference proteome;RNA-binding
GO:0003723; GO:0005829; GO:0005886; GO:0051607
Evidence at protein level
4
null
null
null
PF03787;
IPR010173;IPR005537;
8X5D;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
csm5 Rv2819c
false
Mycobacterium tuberculosis
795
row_72224
false
null
213,211
P9WQC7
MKTKGALIWEFNQPWSVEEIEIGDPRKDEVKIQMEAAGMCRSDHHLVTGDIPMAGFPVLGGHEGAGIVTEVGPGVDDFAPGDHVVLAFIPSCGKCPSCQAGMRNLCDLGAGLLAGESVTDGSFRIQARGQNVYPMTLLGTFSPYMVVHRSSVVKIDPSVPFEVACLVGCGVTTGYGSAVRTADVRPGDDVAIVGLGGVGMAALQGAVSAGARYVFAVEPVEWKRDQALKFGATHVYPDINAALMGIAEVTYGLMAQKVIITVGKLDGADVDSYLTITAKGGTCVLTAIGSLVDTQVTLNLAMLTLLQKNIQGTIFGGGNPHYDIPKLLSMYKAGKLNLDDMVTTAYKLEQINDGYQDMLNGKNIRGVIRYTDDDR
Alcohol dehydrogenase B (EC 1.1.1.1)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
375
39,748
Cytoplasm;Metal-binding;NAD;Oxidoreductase;Reference proteome;Zinc
GO:0004022; GO:0005829; GO:0005886; GO:0008270; GO:0046294; GO:0051903
Evidence at protein level
3
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
null
null
PF08240;PF00107;
IPR013149;IPR013154;IPR023921;IPR002328;IPR011032;IPR036291;IPR020843;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
adhB Rv0761c MTCY369.06c
false
Mycobacterium tuberculosis
796
row_199409
false
null
402,968
O06179
MRTRVAELLGAEFPICAFSHCRDVVAAVSNAGGFGILGAVAHSPKRLESELTWIEEHTGGKPYGVDVLLPPKYIGAEQGGIDAQQARELIPEGHRTFVDDLLVRYGIPAVTDRQRSSSAGGLHISPKGYQPLLDVAFAHDIRLIASALGPPPPDLVERAHNHDVLVAALAGTAQHARRHAAAGVDLIVAQGTEAGGHTGEVATMVLVPEVVDAVSPTPVLAAGGIARGRQIAAALALGAEGVWCGSVWLTTEEAETPPVVKDKFLAATSSDTVRSRSLTGKPARMLRTAWTDEWDRPDSPDPLGMPLQSALVSDPQLRINQAAGQPGAKARELATYFVGQVVGSLDRVRSARSVVLDMVEEFIDTVGQLQGLVQR
Putative monooxygenase Rv1533 (EC 1.13.12.-)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
375
39,620
Flavoprotein;FMN;Monooxygenase;Oxidoreductase;Reference proteome
GO:0018580
Evidence at protein level
2
null
null
null
PF03060;
IPR013785;IPR004136;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
Rv1533
false
Mycobacterium tuberculosis
797
row_385501
false
null
426,040
P65811
MGSRRFDAEVYARRLALAAAATADAGLAGLVITPGYDLCYLIGSRAETFERLTALVLPAAGAPAVVLPRLELAALKQSAAAELGLRVCDWVDGDDPYGLVSAVLGGAPVATAVTDSMPALHMLPLADALGVLPVLATDVLRRLRMVKEETEIDALRKAGAAIDRVHARVPEFLVPGRTEADVAADIAEAIVAEGHSEVAFVIVGSGPHGADPHHGYSDRELREGDIVVVDIGGTYGPGYHSDSTRTYSIGEPDSDVAQSYSMLQRAQRAAFEAIRPGVTAEQVDAAARDVLAEAGLAEYFVHRTGHGIGLCVHEEPYIVAGNDLVLVPGMAFSIEPGIYFPGRWGARIEDIVIVTEDGAVSVNNCPHELIVVPVS
Probable dipeptidase PepE (EC 3.4.13.-)
Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
233,413
375
39,440
Cell membrane;Hydrolase;Manganese;Membrane;Metal-binding;Reference proteome;Transmembrane;Transmembrane helix
GO:0005886; GO:0016787; GO:0046872
Inferred from homology
2
SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
null
TRANSMEM 15..35; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 55..75; /note="Helical"; /evidence="ECO:0000255"
PF01321;PF00557;
IPR029149;IPR036005;IPR000587;IPR000994;IPR050659;IPR001131;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype)
pepE BQ2027_MB2116C
false
Mycobacterium tuberculosis
798
row_408134
false
null
431,770
P9WKI5
MVEIGMGRTARRTYELSEISIVPSRRTRSSKDVSTAWQLDAYRFEIPVVAHPTDALVSPEFAIELGRLGGLGVLNGEGLIGRHLDVEAKIAQLLEAAAADPEPSTAIRLLQELHAAPLNPDLLGAAVARIREAGVTTAVRVSPQNAQWLTPVLVAAGIDLLVIQGTIVSAERVASDGEPLNLKTFISELDIPVVAGGVLDHRTALHLMRTGAAGVIVGYGSTQGVTTTDEVLGISVPMATAIADAAAARRDYLDETGGRYVHVLADGDIHTSGELAKAIACGADAVVLGTPLAESAEALGEGWFWPAAAAHPSLPRGALLQIAVGERPPLARVLGGPSDDPFGGLNLVGGLRRSMAKAGYCDLKEFQKVGLTVGG
Uncharacterized oxidoreductase Rv3410c (EC 1.-.-.-)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
375
38,991
NAD;Oxidoreductase;Reference proteome
GO:0005886; GO:0006183; GO:0016491
Evidence at protein level
2
null
null
null
PF00478;
IPR013785;IPR005990;IPR005992;IPR001093;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
guaB3 Rv3410c MTCY78.18
false
Mycobacterium tuberculosis
799
row_413525
false
null
431,875
P9WMB2
MTQTGKRQRRKFGRIRQFNSGRWQASYTGPDGRVYIAPKTFNAKIDAEAWLTDRRREIDRQLWSPASGQEDRPGAPFGEYAEGWLKQRGIKDRTRAHYRKLLDNHILATFADTDLRDITPAAVRRWYATTAVGTPTMRAHSYSLLRAIMQTALADDLIDSNPCRISGASTARRVHKIRPATLDELETITKAMPDPYQAFVLMAAWLAMRYGELTELRRKDIDLHGEVARVRRAVVRVGEGFKVTTPKSDAGVRDISIPPHLIPAIEDHLHKHVNPGRESLLFPSVNDPNRHLAPSALYRMFYKARKAAGRPDLRVHDLRHSGAVLAASTGATLAELMQRLGHSTAGAALRYQHAAKGRDREIAALLSKLAENQEM
Putative prophage phiRv2 integrase
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
83,331
375
42,176
DNA integration;DNA recombination;DNA-binding;Reference proteome;Viral genome integration;Virus entry into host cell
GO:0003677; GO:0006310; GO:0015074; GO:0044826; GO:0046718; GO:0075713
Inferred from homology
2
null
null
null
PF14659;PF00589;
IPR044068;IPR011010;IPR013762;IPR002104;IPR010998;IPR004107;IPR050090;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
MT2735
false
Mycobacterium tuberculosis
800
row_413630
false
null
26,766
P9WGU1
MKIRLHTLLAVLTAAPLLLAAAGCGSKPPSGSPETGAGAGTVATTPASSPVTLAETGSTLLYPLFNLWGPAFHERYPNVTITAQGTGSGAGIAQAAAGTVNIGASDAYLSEGDMAAHKGLMNIALAISAQQVNYNLPGVSEHLKLNGKVLAAMYQGTIKTWDDPQIAALNPGVNLPGTAVVPLHRSDGSGDTFLFTQYLSKQDPEGWGKSPGFGTTVDFPAVPGALGENGNGGMVTGCAETPGCVAYIGISFLDQASQRGLGEAQLGNSSGNFLLPDAQSIQAAAAGFASKTPANQAISMIDGPAPDGYPIINYEYAIVNNRQKDAATAQTLQAFLHWAITDGNKASFLDQVHFQPLPPAVVKLSDALIATISS
Phosphate-binding protein PstS 1 (PBP 1) (PhoS1) (PstS-1) (38-kDa glycolipoprotein) (38-kDa lipoprotein) (P38) (Antigen Ag78) (Protein antigen B) (Pab)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
374
38,243
3D-structure;Cell adhesion;Cell membrane;Cell wall;Glycoprotein;Lipoprotein;Membrane;Palmitate;Phosphate transport;Reference proteome;Secreted;Signal;Transport;Virulence
GO:0005576; GO:0005829; GO:0005886; GO:0006817; GO:0007155; GO:0009274; GO:0009986; GO:0016036; GO:0035435; GO:0042301; GO:0043190
Evidence at protein level
5
SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305|PubMed:1906192}. Cell surface {ECO:0000269|PubMed:1612766, ECO:0000269|PubMed:25359607}. Secreted, cell wall {ECO:0000269|PubMed:10426995}. Secreted {ECO:0000305|PubMed:16622205, ECO:0000305|PubMed:1906192}. Note=A soluble cell wall-associated protein (PubMed:10426995). Also found in culture filtrate in increasing quantities during growth (PubMed:16622205, PubMed:1906192). {ECO:0000269|PubMed:10426995, ECO:0000269|PubMed:16622205, ECO:0000269|PubMed:1906192}.
SIGNAL 1..23; /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
null
PF12849;
IPR005673;IPR024370;IPR050962;
1PC3;7DM1;7DM2;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
pstS1 phoS1 Rv0934 MTCY08D9.05c
false
Mycobacterium tuberculosis
801
row_23413
false
null
431,805
P9WL63
MRSERLRWLVAAEGPFASVYFDDSHDTLDAVERREATWRDVRKHLESRDAKQELIDSLEEAVRDSRPAVGQRGRALIATGEQVLVNEHLIGPPPATVIRLSDYPYVVPLIDLEMRRPTYVFAAVDHTGADVKLYQGATISSTKIDGVGYPVHKPVTAGWNGYGDFQHTTEEAIRMNCRAVADHLTRLVDAADPEVVFVSGEVRSRTDLLSTLPQRVAVRVSQLHAGPRKSALDEEEIWDLTSAEFTRRRYAEITNVAQQFEAEIGRGSGLAAQGLAEVCAALRDGDVDTLIVGELGEATVVTGKARTTVARDADMLSELGEPVDRVARADEALPFAAIAVGAALVRDDNRIAPLDGVGALLRYAATNRLGSHRS
Uncharacterized protein Rv2629
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
374
40,840
3D-structure;Coiled coil;Direct protein sequencing;Reference proteome
GO:0001666; GO:0005829; GO:0005886; GO:0009274
Evidence at protein level
2
null
null
null
PF18844;
IPR040701;IPR029064;
8V9K;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
Rv2629
false
Mycobacterium tuberculosis
802
row_413560
false
null
546,622
P9WK28
MAAMRAHARRRHPHALMSRAAGLPRLSWFAGLTWFAGGSTGAGCAAHPALAGLTAGARCPAYAAISASTARPAATALPAVAASTARPAATAGTTPATGASGSARPTDAAGMADLARPGVVATHAVRTLGTTGSRAIGLCPSQPLDCPRSPQATLNLGSMGRSLDGPQWRRARVRLCGRWWRRSNTTRGASPRPPSTCRGDNVSMIELEVHQADVTKLELDAITNAANTRLRHAGGVAAAIARAGGPELQRESTEKAPIGLGEAVETTAGDMPARYVIHAATMELGGPTSGEIITAATAATLRKADELGCRSLALVAFGTGVGGFPLDDAARLMVGAVRRHRPGSLQRVVFAVHGDAAERAFSAAIQAGEDTARR
Uncharacterized protein MT1950
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
83,331
374
38,269
Reference proteome
null
Predicted
1
null
null
null
PF01661;
IPR002589;IPR043472;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
MT1950
false
Mycobacterium tuberculosis
803
row_526714
false
null
4,123
I6Y3Q0
MDFTTTEAAQDLGGLVDTIVDAVCTPEHQRELDKLEQRFDRELWRKLIDAGILSSAAPESLGGDGFGVLEQVAVLVALGHQLAAVPYLESVVLAAGALARFGSPELQQGWGVSAVSGDRILTVALDGEMGEGPVQAAGTGHGYRLTGTRTQVGYGPVADAFLVPAETDSGAAVFLVAAGDPGVAVTALATTGLGSVGHLELNGAKVDAARRVGGTDVAVWLGTLSTLSRTAFQLGVLERGLQMTAEYARTREQFDRPIGSFQAVGQRLADGYIDVKGLRLTLTQAAWRVAEDSLASRECPQPADIDVATAGFWAAEAGHRVAHTIVHVHGGVGVDTDHPVHRYFLAAKQTEFALGGATGQLRRIGRELAETPA
Acyl-CoA dehydrogenase FadE27 (ACAD) (EC 1.3.99.-) (3-oxocholest-4-en-26-oyl-CoA dehydrogenase beta subunit)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
373
39,008
3D-structure;Cholesterol metabolism;FAD;Flavoprotein;Lipid degradation;Lipid metabolism;Oxidoreductase;Reference proteome;Steroid metabolism;Sterol metabolism;Virulence
GO:0003995; GO:0006707; GO:0050660
Evidence at protein level
5
null
null
null
PF00441;PF02771;
IPR046373;IPR036250;IPR009075;IPR013786;IPR037069;IPR009100;
4X28;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
fadE27 Rv3505
false
Mycobacterium tuberculosis
804
row_3272
false
null
4,619
O06350
MSSYYARRPLQSSGCSNSDSCWDGAPIEITESGPSVAGRLAALASRMTIKPLMTVGSYLSPLPLPLGFVDFACRVWRPGQGTVRTTINLPNATAQLVRAPGVRAADGAGRVVLYLHGGAFVMCGPNSHSRIVNALSGFAESPVLIVDYRLIPKHSLGMALDDCHDAYQWLRARGYRPEQIVLAGDSAGGYLALALAQRLQCDDEKPAAIVAISPLLQLAKGPKQDHPNIGTDAMFPARAFDALAAWVRAAAAKNMVDGRPEDLYEPLDHIESSLPPTLIHVSGSEVLLHDAQLGAGKLAAAGVCAEVRVWPGQAHLFQLATPLVPEATRSLRQIGQFIRDATADSSLSPVHRSRYVAGSPRAASRGAFGQSPI
Carboxylesterase/phospholipase LipF (EC 3.1.1.1) (EC 3.1.4.3)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
373
39,611
Cell wall;Direct protein sequencing;Hydrolase;Reference proteome;Secreted;Serine esterase;Stress response
GO:0004629; GO:0004806; GO:0005576; GO:0034480; GO:0106435
Evidence at protein level
5
SUBCELLULAR LOCATION: Secreted, cell wall {ECO:0000305|PubMed:18535356}. Note=Detected by antibodies in a wild-type strain and upon expression of a probably truncated form in M.smegmatis. {ECO:0000269|PubMed:18535356}.
null
null
PF07859;
IPR013094;IPR029058;IPR050300;IPR033140;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
lipF Rv3487c
false
Mycobacterium tuberculosis
805
row_3699
false
null
6,614
O53181
MTRSGDEAQLMTGVTGDLAGTELGLTPSLTKNAGVPTTDQPQKGKDFTSDQEVRWCPGCGDYVILNTIRNFLPELGLRRENIVFISGIGCSSRFPYYLETYGFHSIHGRAPAIATGLALAREDLSVWVVTGDGDALSIGGNHLIHALRRNINVTILLFNNRIYGLTKGQYSPTSEVGKVTKSTPMGSLDHPFNPVSLALGAEATFVGRALDSDRNGLTEVLRAAAQHRGAALVEILQDCPIFNDGSFDALRKEGAEERVIKVRHGEPIVFGANGEYCVVKSGFGLEVAKTADVAIDEIIVHDAQVDDPAYAFALSRLSDQNLDHTVLGIFRHISRPTYDDAARSQVVAARNAAPSGTAALQSLLHGRDTWTVD
2-oxoglutarate oxidoreductase subunit KorB (EC 1.2.7.3) (Alpha-ketoglutarate oxidoreductase subunit beta) (KG oxidoreductase subunit beta) (KGO subunit beta) (KOR subunit beta)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
373
40,143
Magnesium;Oxidoreductase;Reference proteome;Tricarboxylic acid cycle
GO:0000287; GO:0005829; GO:0006099; GO:0009274; GO:0016491; GO:0030976; GO:0047553
Evidence at protein level
5
null
null
null
PF02775;
IPR051457;IPR029061;IPR011766;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
korB Rv2454c
false
Mycobacterium tuberculosis
806
row_5448
false
null
27,003
P9WP31
MSANDRRDRRVRVAVVFGGRSNEHAISCVSAGSILRNLDSRRFDVIAVGITPAGSWVLTDANPDALTITNRELPQVKSGSGTELALPADPRRGGQLVSLPPGAGEVLESVDVVFPVLHGPYGEDGTIQGLLELAGVPYVGAGVLASAVGMDKEFTKKLLAADGLPVGAYAVLRPPRSTLHRQECERLGLPVFVKPARGGSSIGVSRVSSWDQLPAAVARARRHDPKVIVEAAISGRELECGVLEMPDGTLEASTLGEIRVAGVRGREDSFYDFATKYLDDAAELDVPAKVDDQVAEAIRQLAIRAFAAIDCRGLARVDFFLTDDGPVINEINTMPGFTTISMYPRMWAASGVDYPTLLATMIETTLARGVGLH
D-alanine--D-alanine ligase (EC 6.3.2.4) (D-Ala-D-Ala ligase) (D-alanine:D-alanine ligase) (D-alanylalanine synthetase)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
373
39,710
3D-structure;ATP-binding;Cell shape;Cell wall biogenesis/degradation;Cytoplasm;Ligase;Magnesium;Manganese;Metal-binding;Nucleotide-binding;Peptidoglycan synthesis;Reference proteome
GO:0005524; GO:0005829; GO:0005886; GO:0008360; GO:0008716; GO:0009252; GO:0046872; GO:0071555
Evidence at protein level
5
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00047}.
null
null
PF07478;PF01820;
IPR011761;IPR013815;IPR000291;IPR005905;IPR011095;IPR011127;IPR016185;
3LWB;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
ddl ddlA Rv2981c MTCY349.06
false
Mycobacterium tuberculosis
807
row_23642
false
null
212,365
P9WG33
MTAQNPNLAALSAAGVSVWLDDLSRDRLRSGNLQELIDTKSVVGVTTNPSIFQKALSEGHTYDAQIAELAARGADVDATIRTVTTDDVRSACDVLVPQWEDSDGVDGRVSIEVDPRLAHETEKTIQQAIELWKIVDRPNLFIKIPATKAGLPAISAVLAEGISVNVTLIFSVQRYREVMDAYLTGMEKARQAGHSLSKIHSVASFFVSRVDTEIDKRLDRIGSRQALELRGQAGVANARLAYATYREVFEDSDRYRSLKVDGARVQRPLWASTGVKNPDYSDTLYVTELVAPHTVNTMPEKTIDAVADHGVIQGDTVTGTASDAQAVFDQLGAIGIDLTDVFAVLEEEGVRKFEASWNELLQETRAHLDTAAQ
Transaldolase (EC 2.2.1.2)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
373
40,721
Cytoplasm;Pentose shunt;Reference proteome;Schiff base;Transferase
GO:0004801; GO:0005576; GO:0005829; GO:0005975; GO:0006098
Evidence at protein level
3
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
null
null
PF00923;
IPR013785;IPR001585;IPR004732;IPR018225;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
tal Rv1448c MTCY493.06
false
Mycobacterium tuberculosis
808
row_198577
false
null
425,441
P63778
MTVVPENFVPGLDGVVAFTTEIAEPDKDGGALRYRGVDIEDLVSQRVTFGDVWALLVDGNFGSGLPPAEPFPLPIHSGDVRVDVQAGLAMLAPIWGYAPLLDIDDATARQQLARASVMALSYVAQSARGIYQPAVPQRIIDECSTVTARFMTRWQGEPDPRHIEAIDAYWVSAAEHGMNASTFTARVIASTGADVAAALSGAIGAMSGPLHGGAPARVLPMLDEVERAGDARSVVKGILDRGEKLMGFGHRVYRAEDPRARVLRAAAERLGAPRYEVAVAVEQAALSELRERRPDRAIETNVEFWAAVVLDFARVPANMMPAMFTCGRTAGWCAHILEQKRLGKLVRPSAIYVGPGPRSPESVDGWERVLTTA
Putative citrate synthase 2 (EC 2.3.3.16)
Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
233,413
373
40,147
3D-structure;Allosteric enzyme;Reference proteome;Transferase;Tricarboxylic acid cycle
GO:0004108; GO:0005829; GO:0005975; GO:0006099
Evidence at protein level
2
null
null
null
PF00285;
IPR016142;IPR016143;IPR002020;IPR019810;IPR036969;
6WGY;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype)
citA BQ2027_MB0913C
false
Mycobacterium tuberculosis
809
row_407542
false
null
39,865
Q79FV4
MRSRQTRDRYRLLPEGYQVTPGRNRHPGTMVGNTPVLWIPELSGTSDPDRGFWAKLEGFNPGGMKDRPALYMVECARARGDIAPGAAIVESTGGTLGLGLALAGKVYRHPVTLVTDPGLEPIIARMLTAYGAGVDMVTQPHPVGGWQQARKDRVAQLMAEYPGAWNPNQYGNPDNVGAYRSLALELVAQLGRIDVLVCSVGTGGHSAGVARVLREFNPDMRLIGVDTIGSTIFGQPASNRLMRGLGSSIYPRNVDYRAFDEVHWVAPPEAVWACRSLAATHYASGGWSVGAVALVAGWAARNLPADTTIAAVFPDGPQRYFDTIYNDAYCNEHELLGGQPPTEPDEIASPLDAVVTRWTRSTTVIDPTQVVS
S-sulfocysteine synthase (EC 2.8.5.1) (O-phospho-L-serine-dependent S-sulfocysteine synthase) (OPS-dependent S-sulfocysteine synthase) (O-phosphoserine sulfhydrylase) (EC 2.5.1.65)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
372
40,118
Amino-acid biosynthesis;Cysteine biosynthesis;Pyridoxal phosphate;Reference proteome;Transferase
GO:0004124; GO:0005737; GO:0005829; GO:0006535; GO:0009274; GO:0016740; GO:0019344; GO:0030170; GO:0033847; GO:0042803; GO:0080146
Evidence at protein level
5
null
null
null
PF00291;
IPR050214;IPR001926;IPR036052;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
cysK2 Rv0848
false
Mycobacterium tuberculosis
810
row_34469
false
null
67,574
I6YEJ7
MASSQLDRQRSRSAKMNRALTAAEWWRLGLMFAVIVALHLVGWLTVTLLVEPARLSLGGKAFGIGVGLTAYTLGLRHAFDADHIAAIDNTTRKLMSDGHRPLAVGFFFSLGHSTVVFGLAVMLVTGLKAIVGPVENDSSTLHHYTGLIGTSISGAFLYLIGILNVIVLVGIVRVFAHLRRGDYDEAELEQQLDNRGLLIRFLGRFTKSLTKSWHMYPVGFLFGLGFDTATEIALLVLAGTSAAAGLPWYAILCLPVLFAAGMCLLDTIDGSFMNFAYGWAFSSPVRKIYYNITVTGLSVAVALLIGSVELLGLIANQLGWQGPFWDWLGGLDLNTVGFVVVAMFALTWAIALLVWHYGRVEERWTPAPDRTT
Nickel transporter NicT (Drug efflux pump NicT)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
372
40,534
Antibiotic resistance;Cell membrane;Ion transport;Membrane;Nickel;Nickel transport;Reference proteome;Transmembrane;Transmembrane helix;Transport
GO:0005886; GO:0044750; GO:0046677; GO:0098716
Evidence at protein level
4
SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000255}.
null
TRANSMEM 30..50; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 55..75; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 104..124; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 152..172; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 218..238; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 245..265; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 294..314; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 335..355; /note="Helical"; /evidence="ECO:0000255"
PF03824;
IPR004688;IPR011541;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
nicT Rv2856
false
Mycobacterium tuberculosis
811
row_58706
false
null
212,343
P9WFW8
MSAHVATLHPEPPFALCGPRGTLIARGVRTRYCDVRAAQAALRSGTAPILLGALPFDVSRPAALMVPDGVLRARKLPDWPTGPLPKVRVAAALPPPADYLTRIGRARDLLAAFDGPLHKVVLARAVQLTADAPLDARVLLRRLVVADPTAYGYLVDLTSAGNDDTGAALVGASPELLVARSGNRVMCKPFAGSAPRAADPKLDAANAAALASSAKNRHEHQLVVDTMRVALEPLCEDLTIPAQPQLNRTAAVWHLCTAITGRLRNISTTAIDLALALHPTPAVGGVPTKAATELIAELEGDRGFYAGAVGWCDGRGDGHWVVSIRCAQLSADRRAALAHAGGGIVAESDPDDELEETTTKFATILTALGVEQ
Putative isochorismate synthase MenF (EC 5.4.4.2) (Isochorismate mutase)
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
83,331
372
38,938
Isomerase;Magnesium;Menaquinone biosynthesis;Metal-binding;Reference proteome
GO:0008909; GO:0009234; GO:0046872
Inferred from homology
3
null
null
null
PF00425;
IPR005801;IPR015890;IPR004561;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
menF entC MT3311
false
Mycobacterium tuberculosis
812
row_198555
false
null
544,659
P64760
MVRRALRLAAGTASLAAGTWLLRALHGTPAALGADAASIRAVSEQSPNYRDGAFVNLDPASMFTLDREELRLIVWELVARHSASRPAAPIPLASPNIYRGDASRLAVSWFGHSTALLEIDGYRVLTDPVWSDRCSPSDVVGPQRLHPPPVQLAALPAVDAVVISHDHYDHLDIDTVVALVGMQRAPFLVPLGVGAHLRSWGVPQDRIVELDWNQSAQVDELTVVCVPARHFSGRFLSRNTTLWASWAFVGPNHRAYFGGDTGYTKSFTQIGADHGPFDLTLLPIGAYNTAWPDIHMNPEEAVRAHLDVTDSGSGMLVPVHWGTFRLAPHPWGEPVERLLAAAEPEHVTVAVPLPGQRVDPTGPMRLHPWWRL
Uncharacterized protein Mb0930
Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
233,413
372
40,641
Reference proteome;Signal
GO:0005737; GO:0008270; GO:0070290
Inferred from homology
1
null
SIGNAL 1..33; /evidence="ECO:0000255"
null
PF12706;
IPR001279;IPR024884;IPR036866;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype)
BQ2027_MB0930
false
Mycobacterium tuberculosis
813
row_524902
false
null
547,051
P9WM50
MKTVVVSGASVAGTAAAYWLGRHGYSVTMVERHPGLRPGGQAIDVRGPALDVLERMGLLAAAQEHKTRIRGASFVDRDGNELFRDTESTPTGGPVNSPDIELLRDDLVELLYGATQPSVEYLFDDSISTLQDDGDSVRVTFERAAAREFDLVIGADGLHSNVRRLVFGPEEQFVKRLGTHAAIFTVPNFLELDYWQTWHYGDSTMAGVYSARNNTEARAALAFMDTELRIDYRDTEAQFAELQRRMAEDGWVRAQLLHYMRSAPDFYFDEMSQILMDRWSRGRVALVGDAGYCCSPLSGQGTSVALLGAYILAGELKAAGDDYQLGFANYHAEFHGFVERNQWLVSDNIPGGAPIPQEEFERIVHSITIKDY
Uncharacterized protein MT1298
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
83,331
372
41,329
Reference proteome
GO:0071949
Predicted
1
null
null
null
PF01494;
IPR002938;IPR036188;IPR051704;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
MT1298
false
Mycobacterium tuberculosis
814
row_527143
false
null
27,063
P9WQB1
MRVGIPTETKNNEFRVAITPAGVAELTRRGHEVLIQAGAGEGSAITDADFKAAGAQLVGTADQVWADADLLLKVKEPIAAEYGRLRHGQILFTFLHLAASRACTDALLDSGTTSIAYETVQTADGALPLLAPMSEVAGRLAAQVGAYHLMRTQGGRGVLMGGVPGVEPADVVVIGAGTAGYNAARIANGMGATVTVLDINIDKLRQLDAEFCGRIHTRYSSAYELEGAVKRADLVIGAVLVPGAKAPKLVSNSLVAHMKPGAVLVDIAIDQGGCFEGSRPTTYDHPTFAVHDTLFYCVANMPASVPKTSTYALTNATMPYVLELADHGWRAACRSNPALAKGLSTHEGALLSERVATDLGVPFTEPASVLA
Alanine dehydrogenase (EC 1.4.1.1) (40 kDa antigen) (TB43)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
371
38,713
3D-structure;Direct protein sequencing;Magnesium;Metal-binding;NAD;Nucleotide-binding;Oxidoreductase;Reference proteome;Secreted
GO:0000166; GO:0000286; GO:0001666; GO:0005576; GO:0005829; GO:0005886; GO:0006524; GO:0009274; GO:0042853; GO:0046872
Evidence at protein level
5
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:10527947}.
null
null
PF01262;PF05222;
IPR008141;IPR008143;IPR008142;IPR007886;IPR007698;IPR036291;
2VHV;2VHW;2VHX;2VHY;2VHZ;2VOE;2VOJ;6O7F;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
ald Rv2780 MTV002.45
false
Mycobacterium tuberculosis
815
row_23701
false
null
426,120
P66027
MDPDRQADIAALDCTLTTVERVLDVEGLRSRIEKLEHEASDPHLWDDQTRAQRVTSELSHTQGELRRVEELRRRLDDLPVLYELAAEEAGAAAADAVAEADAELKSLRADIEATEVRTLLSGEYDEREALVTIRSGAGGVDAADWAEMLMRMYIRWAEQHKYPVEVFDTSYAEEAGIKSATFAVHAPFAYGTLSVEQGTHRLVRISPFDNQSRRQTSFAEVEVLPVVETTDHIDIPEGDVRVDVYRSSGPGGQSVNTTDSAVRLTHIPSGIVVTCQNEKSQLQNKIAAMRVLQAKLLERKRLEERAELDALKADGGSSWGNQMRSYVLHPYQMVKDLRTEYEVGNPAAVLDGDLDGFLEAGIRWRNRRNDD
Peptide chain release factor 2 (RF-2)
Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
233,413
371
41,473
Cytoplasm;Methylation;Protein biosynthesis;Reference proteome
GO:0005737; GO:0016149
Inferred from homology
2
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
null
null
PF03462;PF00472;
IPR005139;IPR000352;IPR045853;IPR004374;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype)
prfB BQ2027_MB3132C
false
Mycobacterium tuberculosis
816
row_408214
false
null
26,765
P9WGT7
MKLNRFGAAVGVLAAGALVLSACGNDDNVTGGGATTGQASAKVDCGGKKTLKASGSTAQANAMTRFVNVFEQACPGQTLNYTANGSGAGISEFNGNQTDFGGSDVPLSKDEAAAAQRRCGSPAWNLPVVFGPIAVTYNLNSVSSLNLDGPTLAKIFNGSITQWNNPAIQALNRDFTLPGERIHVVFRSDESGTTDNFQRYLQAASNGAWGKGAGKSFQGGVGEGARGNDGTSAAAKNTPGSITYNEWSFAQAQHLTMANIVTSAGGDPVAITIDSVGQTIAGATISGVGNDLVLDTDSFYRPKRPGSYPIVLATYEIVCSKYPDSQVGTAVKAFLQSTIGAGQSGLGDNGYIPIPDEFKSRLSTAVNAIA
Phosphate-binding protein PstS 3 (PBP 3) (PstS-3) (Antigen Ag88)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
370
37,953
3D-structure;Cell membrane;Lipoprotein;Membrane;Palmitate;Phosphate transport;Reference proteome;Signal;Stress response;Transport
GO:0005576; GO:0005886; GO:0009274; GO:0016036; GO:0035435; GO:0042301; GO:0043190; GO:0051301; GO:0051701; GO:0052170
Evidence at protein level
5
SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}.
SIGNAL 1..22; /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
null
PF12849;
IPR005673;IPR024370;IPR050962;
4LVQ;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
pstS3 phoS2 Rv0928 MTCY21C12.22
false
Mycobacterium tuberculosis
817
row_23412
false
null
27,091
P9WQP7
MLRRMGDASLTTELGRVLVTGGAGFVGANLVTTLLDRGHWVRSFDRAPSLLPAHPQLEVLQGDITDADVCAAAVDGIDTIFHTAAIIELMGGASVTDEYRQRSFAVNVGGTENLLHAGQRAGVQRFVYTSSNSVVMGGQNIAGGDETLPYTDRFNDLYTETKVVAERFVLAQNGVDGMLTCAIRPSGIWGNGDQTMFRKLFESVLKGHVKVLVGRKSARLDNSYVHNLIHGFILAAAHLVPDGTAPGQAYFINDAEPINMFEFARPVLEACGQRWPKMRISGPAVRWVMTGWQRLHFRFGFPAPLLEPLAVERLYLDNYFSIAKARRDLGYEPLFTTQQALTECLPYYVSLFEQMKNEARAEKTAATVKP
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase (Cholesterol dehydrogenase) [Includes: 3-beta-hydroxy-Delta(5)-steroid dehydrogenase (3-beta-HSD) (3BHSD) (EC 1.1.1.145) (3-beta hydroxysterol dehydrogenase) (3-beta-hydroxy-5-ene steroid dehydrogenase) (Progesterone reductase); Steroid Delta-isomerase (EC 5.3.3.1) (Delta-5-3-ketosteroid isomerase)]
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
370
40,742
Cytoplasm;Isomerase;Lipid degradation;Lipid metabolism;Multifunctional enzyme;NAD;Oxidoreductase;Reference proteome;Steroid metabolism
GO:0003854; GO:0004769; GO:0005829; GO:0005886; GO:0006694; GO:0008202; GO:0016042; GO:0016616; GO:0030283; GO:0070403; GO:0102294
Evidence at protein level
5
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:17630785}.
null
null
PF01073;
IPR002225;IPR050177;IPR036291;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
Rv1106c
false
Mycobacterium tuberculosis
818
row_23724
false
null
81,666
P9WFX5
MALSAEGSSGGSRGGSPKAEAASVPSWPQILGRLTDNRDLARGQAAWAMDQIMTGNARPAQIAAFAVAMTMKAPTADEVGELAGVMLSHAHPLPADTVPDDAVDVVGTGGDGVNTVNLSTMAAIVVAAAGVPVVKHGNRAASSLSGGADTLEALGVRIDLGPDLVARSLAEVGIGFCFAPRFHPSYRHAAAVRREIGVPTVFNLLGPLTNPARPRAGLIGCAFADLAEVMAGVFAARRSSVLVVHGDDGLDELTTTTTSTIWRVAAGSVDKLTFDPAGFGFARAQLDQLAGGDAQANAAAVRAVLGGARGPVRDAVVLNAAGAIVAHAGLSSRAEWLPAWEEGLRRASAAIDTGAAEQLLARWVRFGRQI
Anthranilate phosphoribosyltransferase (EC 2.4.2.18)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
370
37,740
3D-structure;Acetylation;Amino-acid biosynthesis;Aromatic amino acid biosynthesis;Glycosyltransferase;Magnesium;Metal-binding;Reference proteome;Transferase;Tryptophan biosynthesis
GO:0000162; GO:0000287; GO:0004048; GO:0005576; GO:0005829; GO:0005886
Evidence at protein level
4
null
null
null
PF02885;PF00591;
IPR005940;IPR000312;IPR017459;IPR036320;IPR035902;
1ZVW;2BPQ;3QQS;3QR9;3QS8;3QSA;3R6C;3R88;3TWP;3UU1;4GIU;4GKM;4IJ1;4M0R;4N5V;4N8Q;4N93;4OWM;4OWN;4OWO;4OWQ;4OWS;4OWU;4OWV;4X58;4X59;4X5A;4X5B;4X5C;4X5D;4X5E;5BNE;5BYT;5C1R;5C2L;5C7S;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
trpD Rv2192c MTCY190.03c
false
Mycobacterium tuberculosis
819
row_72115
false
null
81,680
P9WGG5
MRTSPMPAKFRSVRVVVITGSVTAAPVRVSETLRRLIDVSVLAENSGREPADERRGDFSAHTEPYRRELLAHCYRMTGSLHDAEDLVQETLLRAWKAYEGFAGKSSLRTWLHRIATNTCLTALEGRRRRPLPTGLGRPSADPSGELVERREVSWLEPLPDVTDDPADPSTIVGNRESVRLAFVAALQHLSPRQRAVLLLRDVLQWKSAEVADAIGTSTVAVNSLLQRARSQLQTVRPSAADRLSAPDSPEAQDLLARYIAAFEAYDIDRLVELFTAEAIWEMPPYTGWYQGAQAIVTLIHQQCPAYSPGDMRLISLIANGQPAAAMYMRAGDVHLPFQLHVLDMAADRVSHVVAFLDTTLFPKFGLPDSL
ECF RNA polymerase sigma factor SigG (ECF sigma factor SigG) (Alternative RNA polymerase sigma factor SigG) (RNA polymerase sigma-G factor) (Sigma-g factor)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
370
40,983
DNA-binding;Reference proteome;Sigma factor;Transcription;Transcription regulation
GO:0001666; GO:0003677; GO:0005886; GO:0006352; GO:0006355; GO:0009415; GO:0016987
Evidence at protein level
4
null
null
null
PF04542;PF08281;PF12680;
IPR032710;IPR039425;IPR014284;IPR014305;IPR000838;IPR007627;IPR013249;IPR013325;IPR013324;IPR037401;IPR036388;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
sigG Rv0182c
false
Mycobacterium tuberculosis
820
row_72129
false
null
81,692
P9WGT9
MKFARSGAAVSLLAAGTLVLTACGGGTNSSSSGAGGTSGSVHCGGKKELHSSGSTAQENAMEQFVYAYVRSCPGYTLDYNANGSGAGVTQFLNNETDFAGSDVPLNPSTGQPDRSAERCGSPAWDLPTVFGPIAITYNIKGVSTLNLDGPTTAKIFNGTITVWNDPQIQALNSGTDLPPTPISVIFRSDKSGTSDNFQKYLDGASNGAWGKGASETFNGGVGVGASGNNGTSALLQTTDGSITYNEWSFAVGKQLNMAQIITSAGPDPVAITTESVGKTIAGAKIMGQGNDLVLDTSSFYRPTQPGSYPIVLATYEIVCSKYPDATTGTAVRAFMQAAIGPGQEGLDQYGSIPLPKSFQAKLAAAVNAIS
Phosphate-binding protein PstS 2 (PBP 2) (PstS-2)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
370
37,864
Cell membrane;Lipoprotein;Membrane;Palmitate;Phosphate transport;Reference proteome;Signal;Transport;Virulence
GO:0005576; GO:0005886; GO:0006817; GO:0035435; GO:0042301; GO:0043190
Evidence at protein level
4
SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}.
SIGNAL 1..22; /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
null
PF12849;
IPR005673;IPR024370;IPR050962;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
pstS2 Rv0932c MTCY08D9.07
false
Mycobacterium tuberculosis
821
row_72141
false
null
94,035
Q79FP0
MSFVVANTEFVSGAAGNLARLGSMISAANSAAAAQTTAVAAAGADEVSAAVAALFGAHGQTYQVLSAQAAAFHSQFVQALSGGAQAYAAAEATNFGPLQPLFDVINAPTLALLNRPLIGNGADGTAANPNGQAGGLLIGNGGNGFSPAAGPGGNGGAAGLLGHGGNGGVGALGANGGAGGTGGWLFGNGGAGGNSGGGGGAGGIGGSAVLFGAGGAGGISPNGMGAGGSGGNGGLFFGNGGAGASSFLGGGGAGGRAFLFGDGGAGGAALSAGSAGRGGDAGFFYGNGGAGGSGAGGASSAHGGAGGQAGLFGNGGEGGDGGALGGNGGNGGNAQLIGNGGDGGDGGGAGAPGLGGRGGLLLGLPGANGT
Ubiquitin-binding protein Rv1468c (PE-PGRS family protein PE_PGRS29)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
370
32,216
Cell wall;Reference proteome;Secreted;Virulence
GO:0005576; GO:0009986
Evidence at protein level
4
SUBCELLULAR LOCATION: Secreted, cell wall {ECO:0000269|PubMed:31036822}. Cell surface {ECO:0000269|PubMed:31036822}.
null
null
PF00934;PF21526;
IPR000084;IPR048996;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
PE_PGRS29 Rv1468c
false
Mycobacterium tuberculosis
822
row_83531
false
null
545,044
P68916
MKRVDTIRPRSRAVRLHVRGLGLPDETAIQLWIVDGRISTEPVAGADTVFDGGWILPGLVDAHCHVGLGKHGNVELDEAIAQAETERDVGALLLRDCGSPTDTRGLDDHEDLPRIIRAGRHLARPKRYIAGFAVELEDESQLPAAVAEQARRGDGWVKLVGDWIDRQIGDLAPLWSDDVLKAAIDTAHAQGARVTAHVFSEDALPGLINAGIDCIEHGTGLTDDTIALMLEHGTALVPTLINLENFPGIADAAGRYPTYAAHMRDLYARGYGRVAAAREAGVPVYAGTDAGSTIEHGRIADEVAALQRIGMTAHEALGAACWDARRWLGRPGLDDRASADLLCYAQDPRQGPGVLQHPDLVILRGRTFGP
Uncharacterized protein Mb2939c
Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
233,413
370
39,770
Reference proteome
GO:0016810
Inferred from homology
1
null
null
null
PF01979;
IPR006680;IPR011059;IPR032466;IPR051781;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype)
BQ2027_MB2939C
false
Mycobacterium tuberculosis
823
row_525286
false
null
112,131
A1KFV6
MKRSGVGSLFAGAHIAEAVPLAPLTTLRVGPIARRVITCTSAEQVVAALRHLDSAAKTGADRPLVFAGGSNLVIAENLTDLTVVRLANSGITIDGNLVRAEAGAVFDDVVVRAIEQGLGGLECLSGIPGSAGATPVQNVGAYGAEVSDTITRVRLLDRCTGEVRWVSARDLRFGYRTSVLKHADGLAVPTVVLEVEFALDPSGRSAPLRYGELIAALNATSGERADPQAVREAVLALRARKGMVLDPTDHDTWSVGSFFTNPVVTQDVYERLAGDAATRKDGPVPHYPAPDGVKLAAGWLVERAGFGKGYPDAGAAPCRLSTKHALALTNRGGATAEDVVTLARAVRDGVHDVFGITLKPEPVLIGCML
UDP-N-acetylenolpyruvoylglucosamine reductase (EC 1.3.1.98) (UDP-N-acetylmuramate dehydrogenase)
Mycobacterium bovis (strain BCG / Pasteur 1173P2)
410,289
369
38,521
Cell cycle;Cell division;Cell shape;Cell wall biogenesis/degradation;Cytoplasm;FAD;Flavoprotein;NADP;Oxidoreductase;Peptidoglycan synthesis
GO:0005829; GO:0008360; GO:0008762; GO:0009252; GO:0051301; GO:0071555; GO:0071949
Inferred from homology
3
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00037}.
null
null
PF01565;PF02873;
IPR016166;IPR036318;IPR016167;IPR016169;IPR003170;IPR011601;IPR036635;IPR006094;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype), Mycobacterium tuberculosis variant bovis BCG (no rank)
murB BCG_0523
false
Mycobacterium tuberculosis
824
row_100598
false
null
213,239
P9WQL3
MSKLQLRAVVADRRLDVEFSVSAGEVLAVLGPNGAGKSTALHVIAGLLRPDAGLVRLGDRVLTDTEAGVNVATHDRRVGLLLQDPLLFPHLSVAKNVAFGPQCRRGMFGSGRARTRASALRWLREVNAEQFADRKPRQLSGGQAQRVAIARALAAEPDVLLLDEPLTGLDVAAAAGIRSVLRSVVARSGCAVVLTTHDLLDVFTLADRVLVLESGTIAEIGPVADVLTAPRSRFGARIAGVNLVNGTIGPDGSLRTQSGAHWYGTPVQDLPTGHEAIAVFPPTAVAVYPEPPHGSPRNIVGLTVAEVDTRGPTVLVRGHDQPGGAPGLAACITVDAATELRVAPGSRVWFSVKAQEVALHPAPHQHASS
Molybdenum import ATP-binding protein ModC (EC 7.3.2.5)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
369
38,610
ATP-binding;Cell membrane;Membrane;Molybdenum;Nucleotide-binding;Reference proteome;Translocase;Transport
GO:0005524; GO:0005886; GO:0015412; GO:0016887; GO:0022857; GO:0055085
Evidence at protein level
3
SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01705}; Peripheral membrane protein {ECO:0000255|HAMAP-Rule:MF_01705}.
null
null
PF00005;PF03459;
IPR003593;IPR003439;IPR017871;IPR008995;IPR050334;IPR004606;IPR027417;IPR005116;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
modC Rv1859 MTCY359.14
false
Mycobacterium tuberculosis
825
row_199437
false
null
7,283
O69652
MSGGACIAVRSLSRSWTDNAIRLIEADARRSADTHLLRYPLPAAWCTDVDVELYLKDETTHITGSLKHRLARSLFLYALCNGWINENTTVVEASSGSTAVSEAYFAALLGLPFIAVMPAATSASKIALIESQGGRCHFVQNSSQVYAEAERVAKETGGHYLDQFTNAERATDWRGNNNIAESIYVQMREEKHPTPEWIVVGAGTGGTSATIGRYIRYRRHATRLCVVDPENSAFFPAYSEGRYDIVMPTSSRIEGIGRPRVEPSFLPGVVDRMVAVPDAASIAAARHVSAVLGRRVGPSTGTNLWGAFGLLAEMVKQGRSGSVVTLLADSGDRYADTYFSDEWVSAQGLDPAGPAAALVEFERSCRWT
L-cysteine desulfhydrase Cds1 (EC 4.4.1.1)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
368
39,957
Cytoplasm;Direct protein sequencing;Lyase;Pyridoxal phosphate;Reference proteome
GO:0005737; GO:0005829; GO:0005886; GO:0016829; GO:0019344; GO:0019450; GO:0030170; GO:0042762; GO:0045454; GO:0070814; GO:1901857
Evidence at protein level
5
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
null
null
PF00291;
IPR047586;IPR050214;IPR001926;IPR036052;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
cds1 Rv3684
false
Mycobacterium tuberculosis
826
row_6021
false
null
27,058
P9WQ75
MTSGSLQFTVLRAVNPATDAQRESMLREPGFGKYHTDHMVSIDYAEGRGWHNARVIPYGPIELDPSAIVLHYAQEVFEGLKAYRWADGSIVSFRADANAARLRSSARRLAIPELPDAVFIESLRQLIAVDKAWVPGAGGEEALYLRPFIFATEPGLGVRPATQYRYLLIASPAGAYFKGGIAPVSVWVSTEYVRACPGGTGAAKFGGNYAASLLAQAEAAENGCDQVVWLDAVERRYIEEMGGMNIFFVLGSGGSARLVTPELSGSLLPGITRDSLLQLAIDAGFAVEERRIDIDEWQKKAAAGEITEVFACGTAAVITPVARVRHGASEFRIADGQPGEVTMALRDTLTGIQRGTFADTHGWMARLG
Branched-chain-amino-acid aminotransferase (BCAT) (EC 2.6.1.42)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
368
39,666
3D-structure;Amino-acid biosynthesis;Aminotransferase;Branched-chain amino acid biosynthesis;Pyridoxal phosphate;Reference proteome;Transferase
GO:0004084; GO:0009081; GO:0009082; GO:0009097; GO:0009098; GO:0009099; GO:0018272; GO:0030170; GO:0052654; GO:0052655; GO:0052656; GO:0071267
Evidence at protein level
5
null
null
null
PF01063;
IPR001544;IPR018300;IPR036038;IPR005786;IPR043132;IPR043131;IPR033939;
3HT5;5U3F;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
ilvE Rv2210c MTCY190.21c
false
Mycobacterium tuberculosis
827
row_23696
false
null
81,723
P9WHW9
MLWHAMPPELNTARLMAGAGPAPMLAAAAGWQTLSAALDAQAVELTARLNSLGEAWTGGGSDKALAAATPMVVWLQTASTQAKTRAMQATAQAAAYTQAMATTPSLPEIAANHITQAVLTATNFFGINTIPIALTEMDYFIRMWNQAALAMEVYQAETAVNTLFEKLEPMASILDPGASQSTTNPIFGMPSPGSSTPVGQLPPAATQTLGQLGEMSGPMQQLTQPLQQVTSLFSQVGGTGGGNPADEEAAQMGLLGTSPLSNHPLAGGSGPSAGAGLLRAESLPGAGGSLTRTPLMSQLIEKPVAPSVMPAAAAGSSATGGAAPVGAGAMGQGAQSGGSTRPGLVAPAPLAQEREEDDEDDWDEEDDW
PPE family immunomodulator PPE68
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
368
37,330
Cell membrane;Cell wall;Membrane;Reference proteome;Secreted;Virulence
GO:0005576; GO:0005886; GO:0009986; GO:0052572
Evidence at protein level
4
SUBCELLULAR LOCATION: Secreted, cell wall {ECO:0000269|PubMed:14573626, ECO:0000269|PubMed:15039340}. Cell membrane {ECO:0000269|PubMed:14573626, ECO:0000269|PubMed:15039340}. Cell surface {ECO:0000269|PubMed:24467650}. Note=Detected predominantly in the membrane and cell wall fractions. {ECO:0000269|PubMed:14573626, ECO:0000269|PubMed:15039340}.
null
null
PF00823;
IPR000030;IPR038332;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
PPE68 Rv3873
false
Mycobacterium tuberculosis
828
row_72171
false
null
81,949
P9WQB9
MKTTAAVLFEAGKPFELMELDLDGPGPGEVLVKYTAAGLCHSDLHLTDGDLPPRFPIVGGHEGSGVIEEVGAGVTRVKPGDHVVCSFIPNCGTCRYCCTGRQNLCDMGATILEGCMPDGSFRFHSQGTDFGAMCMLGTFAERATVSQHSVVKVDDWLPLETAVLVGCGVPSGWGTAVNAGNLRAGDTAVIYGVGGLGINAVQGATAAGCKYVVVVDPVAFKRETALKFGATHAFADAASAAAKVDELTWGQGADAALILVGTVDDEVVSAATAVIGKGGTVVITGLADPAKLTVHVSGTDLTLHEKTIKGSLFGSCNPQYDIVRLLRLYDAGQLMLDELVTTTYNLEQVNQGYQDLRDGKNIRGVIVH
Putative alcohol dehydrogenase D (EC 1.1.1.1)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
368
38,342
Metal-binding;NAD;Oxidoreductase;Reference proteome;Zinc
GO:0004022; GO:0005829; GO:0008270; GO:0009274; GO:0010447; GO:0046294; GO:0051701; GO:0051903
Evidence at protein level
4
null
null
null
PF08240;PF00107;
IPR013149;IPR013154;IPR023921;IPR002328;IPR011032;IPR036291;IPR020843;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
adhD Rv3086
false
Mycobacterium tuberculosis
829
row_72386
false
null