Datasets:
manufernandezbur
/
tox_nontox_clustered_2025

Dataset card Data Studio Files
xet
Community
1
Unnamed: 0
int64
2
562k
Entry
stringlengths
6
10
Sequence
stringlengths
11
999
Protein names
stringlengths
5
558
Organism
stringclasses
392 values
Organism (ID)
int64
595
2.89M
Length
int64
11
999
Mass
int64
1.06k
118k
Keywords
stringlengths
4
380
⌀
Gene Ontology IDs
stringlengths
10
754
⌀
Protein existence
stringclasses
5 values
Annotation
float64
1
5
Subcellular location [CC]
stringlengths
30
2.26k
⌀
Signal peptide
stringclasses
677 values
Transmembrane
stringlengths
32
2.52k
⌀
Pfam
stringlengths
8
72
⌀
InterPro
stringlengths
10
180
⌀
PDB
stringlengths
5
2.65k
⌀
Taxonomic lineage
stringclasses
178 values
Gene Names
stringlengths
2
299
⌀
Toxin
bool
2 classes
species
stringclasses
111 values
cdhit_cluster
int64
0
4.65k
cdhit_rep
stringlengths
5
10
cdhit_rep_is_ref
bool
1 class
cdhit_pct_id
float64
425,788
P64866
MKFVVASYGTRGDIEPCAAVGLELQRRGHDVCLAVPPNLIGFVETAGLSAVAYGSRDSQEQLDEQFLHNAWKLQNPIKLLREAMAPVTEGWAELSAMLTPVAAGADLLLTGQIYQEVVANVAEHHGIPLAALHFYPVRANGEIAFPARLPAPLVRSTITAIDWLYWRMTKGVEDAQRRELGLPKASTPAPRRMAVRGSLEIQAYDALCFPGLAAEWGGRRPFVGALTMESATDADDEVASWIAADTPPIYFGFGSMPIGSLADRVAMISAACAELGERALICSGPSDATGIPQFDHVKVVRVVSHAAVFPTCRAVVHHGGAGTTAAGLRAGIPTLILWVTSDQPIWAAQIKQLKVGRGRRFSSATKESLIADLRTILAPDYVTRAREIASRMTKPAASVTATADLLEDAARRAR
Uncharacterized glycosyltransferase Mb1551 (EC 2.4.-.-)
Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
233,413
414
44,362
Glycosyltransferase;Reference proteome;Transferase
GO:0005975; GO:0008194; GO:0016758; GO:0030259; GO:0033072
Inferred from homology
2
null
null
null
PF06722;PF03033;
IPR010610;IPR050426;IPR004276;IPR002213;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype)
BQ2027_MB1551
false
Mycobacterium tuberculosis
630
row_407882
false
null
432,127
P9WPH5
MNDNQLAPVARPRSPLELLDTVPDSLLRRLKQYSGRLATEAVSAMQERLPFFADLEASQRASVALVVQTAVVNFVEWMHDPHSDVGYTAQAFELVPQDLTRRIALRQTVDMVRVTMEFFEEVVPLLARSEEQLTALTVGILKYSRDLAFTAATAYADAAEARGTWDSRMEASVVDAVVRGDTGPELLSRAAALNWDTTAPATVLVGTPAPGPNGSNSDGDSERASQDVRDTAARHGRAALTDVHGTWLVAIVSGQLSPTEKFLKDLLAAFADAPVVIGPTAPMLTAAHRSASEAISGMNAVAGWRGAPRPVLARELLPERALMGDASAIVALHTDVMRPLADAGPTLIETLDAYLDCGGAIEACARKLFVHPNTVRYRLKRITDFTGRDPTQPRDAYVLRVAATVGQLNYPTPH
Uncharacterized protein Rv2242
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
414
44,638
3D-structure;Reference proteome
GO:0003700; GO:0045893
Evidence at protein level
2
null
null
null
PF17853;PF13556;
IPR051448;IPR041522;IPR025736;IPR042070;
9F80;9FB1;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
Rv2242 MTCY427.23
false
Mycobacterium tuberculosis
631
row_413872
false
null
81,880
P9WNS1
MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS
1-deoxy-D-xylulose 5-phosphate reductoisomerase (DXP reductoisomerase) (EC 1.1.1.267) (1-deoxyxylulose-5-phosphate reductoisomerase) (2-C-methyl-D-erythritol 4-phosphate synthase)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
413
42,853
3D-structure;Isoprene biosynthesis;Manganese;Metal-binding;NADP;Oxidoreductase;Reference proteome
GO:0000287; GO:0030145; GO:0030604; GO:0050897; GO:0051483; GO:0051484; GO:0070402
Evidence at protein level
4
null
null
null
PF08436;PF02670;PF13288;
IPR003821;IPR013644;IPR013512;IPR026877;IPR036169;IPR036291;
2C82;2JCV;2JCX;2JCY;2JD0;2JD1;2JD2;2Y1C;2Y1D;2Y1E;2Y1F;2Y1G;3RAS;3ZHX;3ZHY;3ZHZ;3ZI0;4A03;4AIC;4OOE;4OOF;4RCV;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
dxr Rv2870c MTCY274.01c
false
Mycobacterium tuberculosis
632
row_72321
false
null
212,753
P9WJX7
MTAPTGTSATTTRPWTPRIATQLSVLACAAFIYVTAEILPVGALSAIARNLRVSVVLVGTLLSWYALVAAVTTVPLVRWTAHWPRRRALVVSLVCLTVSQLVSALAPNFAVLAAGRVLCAVTHGLLWAVIAPIATRLVPPSHAGRATTSIYIGTSLALVVGSPLTAAMSLMWGWRLAAVCVTGAAAAVALAARLALPEMVLRADQLEHVGRRARHHRNPRLVKVSVLTMIAVTGHFVSYTYIVVIIRDVVGVRGPNLAWLLAAYGVAGLVSVPLVARPLDRWPKGAVIVGMTGLTAAFTLLTALAFGERHTAATALLGTGAIVLWGALATAVSPMLQSAAMRSGGDDPDGASGLYVTAFQIGIMAGALLGGLLYERSLAMMLTASAGLMGVALFGMTVSQHLFENPTLSPGDG
Chloramphenicol efflux pump Rv0191
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
413
42,911
Antibiotic resistance;Cell membrane;Membrane;Reference proteome;Transmembrane;Transmembrane helix;Transport
GO:0005886; GO:0022857; GO:0046677; GO:0055085
Evidence at transcript level
3
SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000255}.
null
TRANSMEM 23..43; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 55..75; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 89..109; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 110..130; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 150..170; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 176..196; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 226..246; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 256..276; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 286..306; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 312..332; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 353..373; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 378..398; /note="Helical"; /evidence="ECO:0000255"
PF07690;
IPR011701;IPR020846;IPR050189;IPR036259;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
Rv0191
false
Mycobacterium tuberculosis
633
row_198957
false
null
431,440
P9WHX3
MLDFAQLPPEVNSALMYAGPGSGPMLAAAAAWEALAAELQTTASTYDALITGLADGPWQGSSAASMVAAATPQVAWLRSTAGQAEQAGSQAVAAASAYEAAFFATVPPPEIAANRALLMALLATNFLGQNTAAIAATEAQYAEMWAQDAAAMYGYAGASAAATQLSPFNPAAQTINPAGLASQAASVGQAVSGAANAQALTDIPKALFGLSGIFTNEPPWLTDLGKALGLTGHTWSSDGSGLIVGGVLGDFVQGVTGSAELDASVAMDTFGKWVSPARLMVTQFKDYFGLAHDLPKWASEGAKAAGEAAKALPAAVPAIPSAGLSGVAGAVGQAASVGGLKVPAVWTATTPAASPAVLAASNGLGAAAAAEGSTHAFGGMPLMGSGAGRAFNNFAAPRYGFKPTVIAQPPAGG
Uncharacterized PPE family protein PPE65
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
413
40,680
Reference proteome
GO:0035435; GO:0052572
Inferred from homology
2
null
null
null
PF00823;PF12484;
IPR022171;IPR000030;IPR038332;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
PPE65 Rv3621c
false
Mycobacterium tuberculosis
634
row_413199
false
null
546,792
P9WL66
MASSASDGTHERSAFRLSPPVLSGAMGPFMHTGLYVAQSWRDYLGQQPDKLPIARPTIALAAQAFRDEIVLLGLKARRPVSNHRVFERISQEVAAGLEFYGNRGWLEKPSGFFAQPPPLTEVAVRKVKDRRRSFYRIFFDSGFTPHPGEPGSQRWLSYTANNREYALLLRHPEPRPWLVCVHGTEMGRAPLDLAVFRAWKLHDELGLNIVMPVLPMHGPRGQGLPKGAVFPGEDVLDDVHGTAQAVWDIRRLLSWIRSQEEESLIGLNGLSLGGYIASLVASLEEGLACAILGVPVADLIELLGRHCGLRHKDPRRHTVKMAEPIGRMISPLSLTPLVPMPGRFIYAGIADRLVHPREQVTRLWEHWGKPEIVWYPGGHTGFFQSRPVRRFVQAALEQSGLLDAPRTQRDRSA
Uncharacterized protein MT2702
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
83,331
413
46,153
Reference proteome
null
Evidence at transcript level
1
null
null
null
null
IPR029058;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
MT2702
false
Mycobacterium tuberculosis
635
row_526884
false
null
112,172
A1KIM6
MSVANLKDLLAEGVSGRGVLVRSDLNVPLDEDGTITDAGRIIASAPTLKALLDADAKVVVAAHLGRPKDGPDPTLSLAPVAVALGEQLGRHVQLAGDVVGADALARAEGLTGGDILLLENIRFDKRETSKNDDDRRALAKQLVELVGTGGVFVSDGFGVVHRKQASVYDIATLLPHYAGTLVADEMRVLEQLTSSTQRPYAVVLGGSKVSDKLGVIESLATKADSIVIGGGMCFTFLAAQGFSVGTSLLEDDMIEVCRGLLETYHDVLRLPVDLVVTEKFAADSPPQTVDVGAVPNGLMGLDIGPGSIKRFSTLLSNAGTIFWNGPMGVFEFPAYAAGTRGVAEAIVAATGKGAFSVVGGGDSAAAVRAMNIPEGAFSHISTGGGASLEYLEGKTLPGIEVLSREQPTGGVL
Phosphoglycerate kinase (EC 2.7.2.3)
Mycobacterium bovis (strain BCG / Pasteur 1173P2)
410,289
412
42,512
ATP-binding;Cytoplasm;Glycolysis;Kinase;Nucleotide-binding;Transferase
GO:0004618; GO:0005524; GO:0005829; GO:0006094; GO:0006096; GO:0043531
Inferred from homology
3
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00145}.
null
null
PF00162;
IPR001576;IPR015911;IPR015824;IPR036043;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype), Mycobacterium tuberculosis variant bovis BCG (no rank)
pgk BCG_1498
false
Mycobacterium tuberculosis
636
row_100637
false
null
431,213
P9WGJ7
MKIRTLSGSVLEPPSAVRATPGTSMLKLEPGGSTIPKIPFIRPSFPGPAELAEDFVQIAQANWYTNFGPNERRFARALRDYLGPHLHVATLANGTLALLAALHVSFGAGTRDRYLLMPSFTFVGVAQAALWTGYRPWFIDIDANTWQPCVHSARAVIERFRDRIAGILLANVFGVGNPQISVWEELAAEWELPIVLDSAAGFGSTYADGERLGGRGACEIFSFHATKPFAVGEGGALVSRDPRLVEHAYKFQNFGLVQTRESIQLGMNGKLSEISAAIGLRQLVGLDRRLASRRKVLECYRTGMADAGVRFQDNANVASLCFASACCTSADHKAAVLGSLRRHAIEARDYYNPPQHRHPYFVTNAELVESTDLAVTADICSRIVSLPVHDHMAPDDVARVVAAVQEAEVRGE
Protein Rv3402c
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
412
44,897
Pyridoxal phosphate;Reference proteome
GO:0000271; GO:0005576; GO:0008483; GO:0010106; GO:0030170; GO:0044847
Evidence at transcript level
2
null
null
null
PF01041;
IPR000653;IPR015424;IPR015421;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
Rv3402c MTCY78.26
false
Mycobacterium tuberculosis
637
row_412972
false
null
536,583
I6XFZ8
MGGCGSADSWVEAAPAQGWPAQYGDAANSSYTTTNGATNLTLRWTRSVKGSLAAGPALSARGYLALNGQTPAGCSLMEWQNDNNGRQRWCVRLVQGGGFAGPLFDGFDNLYVGQPGAIISFPPTQWTRWRQPVIGMPSTPRFLGHGRLLVSTHLGQLLVFDTRRGMVVGSPVDLVDGIDPTDATRGLADCAPARPGCPVAAAPAFSSVNGTVVVSVWQPGEPAAKLVGLKYHAEQLVREWTSDAVSAGVLASPVLSADGSTVYVNGRDHRLWALNAADGKAKWSAPLGFLAQTPPALTPHGLIVSGGGPDTALAAFRDAGDHAEGAWRRDDVTALSTASLAGTGVGYTVISGPNHDGTPGLSLLVFDPANGHTVNSYPLPGATGYPVGVSVGNDRRVVTATSDGQVYSFAP
Protein Rv3035
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
411
42,539
Direct protein sequencing;Reference proteome
null
Evidence at protein level
1
null
null
null
PF13360;
IPR002372;IPR011047;IPR015943;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
Rv3035 RVBD_3035 P425_03163
false
Mycobacterium tuberculosis
638
row_516892
false
null
26,749
P9WGK5
MTVFSALLLAGVLSALALAVGGAVGMRLTSRVVEQRQRVATEWSGITVSQMLQCIVTLMPLGAAVVDTHRDVVYLNERAKELGLVRDRQLDDQAWRAARQALGGEDVEFDLSPRKRSATGRSGLSVHGHARLLSEEDRRFAVVFVHDQSDYARMEAARRDFVANVSHELKTPVGAMALLAEALLASADDSETVRRFAEKVLIEANRLGDMVAELIELSRLQGAERLPNMTDVDVDTIVSEAISRHKVAADNADIEVRTDAPSNLRVLGDQTLLVTALANLVSNAIAYSPRGSLVSISRRRRGANIEIAVTDRGIGIAPEDQERVFERFFRGDKARSRATGGSGLGLAIVKHVAANHDGTIRVWSKPGTGSTFTLALPALIEAYHDDERPEQAREPELRSNRSQREEELSR
Sensor-like histidine kinase SenX3 (EC 2.7.13.3)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
410
44,825
ATP-binding;Cell membrane;Kinase;Membrane;Nucleotide-binding;Phosphoprotein;Reference proteome;Stress response;Transferase;Transmembrane;Transmembrane helix;Two-component regulatory system;Virulence
GO:0000155; GO:0000160; GO:0005524; GO:0005576; GO:0005886; GO:0009927; GO:1990748
Evidence at protein level
5
SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000255}.
null
TRANSMEM 6..26; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 46..66; /note="Helical"; /evidence="ECO:0000255"
PF02518;PF00512;
IPR050351;IPR036890;IPR005467;IPR003661;IPR036097;IPR004358;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
senX3 Rv0490 MTCY20G9.16
false
Mycobacterium tuberculosis
639
row_23396
false
null
81,725
P9WI05
MLDFGALPPEINSGRMYAGPGSGPLLAAAAAWDALAAELYSAAASYGSTIEGLTVAPWMGPSSITMAAAVAPYVAWISVTAGQAEQAGAQAKIAAGVYETAFAATVPPPVIEANRALLMSLVATNIFGQNTPAIAATEAHYAEMWAQDAAAMYGYAGSSATASQLAPFSEPPQTTNPSATAAQSAVVAQAAGAAASSDITAQLSQLISLLPSTLQSLATTATATSASAGWDTVLQSITTILANLTGPYSIIGLGAIPGGWWLTFGQILGLAQNAPGVAALLGPKAAAGALSPLAPLRGGYIGDITPLGGGATGGIARAIYVGSLSVPQGWAEAAPVMRAVASVLPGTGAAPALAAEAPGALFGEMALSSLAGRALAGTAVRSGAGAARVAGGSVTEDVASTTTIIVIPAD
PPE family protein PPE32
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
410
40,030
Cell wall;Direct protein sequencing;Reference proteome;Secreted;Virulence
GO:0009986; GO:0010961; GO:0052572; GO:0141184; GO:1903830
Evidence at protein level
4
SUBCELLULAR LOCATION: Secreted, cell wall {ECO:0000269|PubMed:24525621}. Cell surface {ECO:0000269|PubMed:24525621}.
null
null
PF00823;PF12484;
IPR022171;IPR000030;IPR038332;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
PPE32 Rv1808
false
Mycobacterium tuberculosis
640
row_72173
false
null
112,203
A1KKJ6
MKDTVSQPAGGRGATAPRPADAASPSCGSSPSADSLSVVLAGGGTAGHVEPAMAVADALVALDPRVRITALGTPRGLETRLVPQRGYHLELITAVPMPRKPGGDLARLPSRVWRAVREARDVLDDVDADVVVGFGGYVALPAYLAARGLPLPPRRRRRIPVVIHEANARAGLANRVGAHTADRVLSAVPDSGLRRAEVVGVPVRASIAALDRAVLRAEARAHFGFPDDARVLLVFGGSQGAVSLNRAVSGAAADLAAAGVCVLHAHGPQNVLELRRRAQGDPPYVAVPYLDRMELAYAAADLVICRAGAMTVAEVSAVGLPAIYVPLPIGNGEQRLNALPVVNAGGGMVVADAALTPELVARQVAGLLTDPARLAAMTAAAARVGHRDAAGQVARAALAVATGAGARTTT
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase (EC 2.4.1.227) (Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase)
Mycobacterium bovis (strain BCG / Pasteur 1173P2)
410,289
410
41,858
Cell cycle;Cell division;Cell membrane;Cell shape;Cell wall biogenesis/degradation;Glycosyltransferase;Membrane;Peptidoglycan synthesis;Transferase
GO:0005886; GO:0005975; GO:0008360; GO:0009252; GO:0030259; GO:0050511; GO:0051301; GO:0051991; GO:0071555
Inferred from homology
3
SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_00033}; Peripheral membrane protein {ECO:0000255|HAMAP-Rule:MF_00033}; Cytoplasmic side {ECO:0000255|HAMAP-Rule:MF_00033}.
null
null
PF04101;PF03033;
IPR006009;IPR007235;IPR004276;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype), Mycobacterium tuberculosis variant bovis BCG (no rank)
murG BCG_2170c
false
Mycobacterium tuberculosis
641
row_100668
false
null
112,263
A1KNE8
MTTFGHDTWWLVAAKAIAVFVFLMLTVLVAILAERKLLGRMQLRPGPNRVGPKGALQSLADGIKLALKESITPGGIDRFVYFVAPIISVIPAFTAFAFIPFGPEVSVFGHRTPLQITDLPVAVLFILGLSAIGVYGIVLGGWASGSTYPLLGGVRSTAQVISYEVAMGLSFATVFLMAGTMSTSQIVAAQDGVWYAFLLLPSFVIYLISMVGETNRAPFDLPEAEGELVAGFHTEYSSLKFAMFMLAEYVNMTTVSALAATLFFGGWHAPWPLNMWASANTGWWPLIWFTAKVWGFLFIYFWLRATLPRLRYDQFMALGWKLLIPVSLVWVMVAAIIRSLRNQGYQYWTPTLVFSSIVVAAAMVLLLRKPLSAPGARASARQRGDEGTSPEPAFPTPPLLAGATKENAGG
NADH-quinone oxidoreductase subunit H (EC 7.1.1.-) (NADH dehydrogenase I subunit H) (NDH-1 subunit H)
Mycobacterium bovis (strain BCG / Pasteur 1173P2)
410,289
410
44,658
Cell membrane;Membrane;NAD;Quinone;Translocase;Transmembrane;Transmembrane helix
GO:0003954; GO:0005886; GO:0009060; GO:0016655; GO:0048038
Inferred from homology
3
SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01350}; Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01350}.
null
TRANSMEM 11..31; /note="Helical"; /evidence="ECO:0000255|HAMAP-Rule:MF_01350"; TRANSMEM 79..99; /note="Helical"; /evidence="ECO:0000255|HAMAP-Rule:MF_01350"; TRANSMEM 119..139; /note="Helical"; /evidence="ECO:0000255|HAMAP-Rule:MF_01350"; TRANSMEM 160..180; /note="Helical"; /evidence="ECO:0000255|HAMAP-Rule:MF_01350"; TRANSMEM 192..212; /note="Helical"; /evidence="ECO:0000255|HAMAP-Rule:MF_01350"; TRANSMEM 257..277; /note="Helical"; /evidence="ECO:0000255|HAMAP-Rule:MF_01350"; TRANSMEM 283..303; /note="Helical"; /evidence="ECO:0000255|HAMAP-Rule:MF_01350"; TRANSMEM 317..337; /note="Helical"; /evidence="ECO:0000255|HAMAP-Rule:MF_01350"; TRANSMEM 347..367; /note="Helical"; /evidence="ECO:0000255|HAMAP-Rule:MF_01350"
PF00146;
IPR001694;IPR018086;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype), Mycobacterium tuberculosis variant bovis BCG (no rank)
nuoH BCG_3175
false
Mycobacterium tuberculosis
642
row_100728
false
null
471,315
Q50700
MATIAQRLRDDHGVAASESSVRRWIATHFAEEVARERVTVPRGPVDAGSEAQIDYGRLGMWFDPATARRVAVWAFVMVLAFSRHLFVRPVIRMDQTAWCACHVAAFEFFDGVPARLVCDNLRTGVDKPDLYDPQINRSYAELASHYATLVDPARARKPKDKPRVERPMTYVRDSFWKGREFDSLAQMQQAAVTWSTEVAGLRYLRALEGAQPLRMFEAVEQQALIALPPRAFELTSWSIGTVGVDTHLKVGKALYSVPWRLIGQRLHARTAGDVVQIFAGNDVVATHVRRPSGRSTDFSHYPPEKIAFHMRTPTWCRHTAELVGPASQQVIAEFMRDNAIHHLRSAQGVLGLRDKHGCDRLEAACARAIEVGDPSYRTIKGILVAGTEHAANEPTTSSPASTAGGVPARP
Putative transposase Rv3428c
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
410
45,494
Reference proteome;Transposable element
GO:0003676; GO:0005576; GO:0005886; GO:0015074
Inferred from homology
2
null
null
null
PF22483;PF00665;
IPR001584;IPR054353;IPR012337;IPR036397;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
Rv3428c MTCY78.01
false
Mycobacterium tuberculosis
643
row_452580
false
null
6,616
O53289
MPAKVSVLITVTGMDQPGVTSALFEVLAQHGVELLNVEQVVIRGRLTLGVLVSCPLDVADGTALRDDVAAAIHGVGLDVAIERSDDLPIIRQPSTHTIFVLGRPITAGAFSAVARGVAALGVNIDFIRGISDYPVTGLELRVSVPPGCVGPLQIALTKVAAEEHVDVAVEDYGLAWRTKRLIVFDVDSTLVQGEVIEMLAARAGAQGQVAAITEAAMRGELDFAESLQRRVATLAGLPATVIDDVAEQLELMPGARTTIRTLRRLGFRCGVVSGGFRRIIEPLARELMLDFVASNELEIVDGILTGRVVGPIVDRPGKAKALRDFASQYGVPMEQTVAVGDGANDIDMLGAAGLGIAFNAKPALREVADASLSHPYLDTVLFLLGVTRGEIEAADAGDCGVRRVEIPAD
Phosphoserine phosphatase SerB2 (PSP) (PSPase) (EC 3.1.3.3) (O-phosphoserine phosphohydrolase) (Protein-serine/threonine phosphatase) (EC 3.1.3.16)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
409
43,059
Amino-acid biosynthesis;Host cytoplasm;Hydrolase;Magnesium;Metal-binding;Reference proteome;Secreted;Serine biosynthesis
GO:0000287; GO:0004722; GO:0005576; GO:0005737; GO:0006470; GO:0006564; GO:0016311; GO:0016597; GO:0036424; GO:0044164; GO:0141032
Evidence at protein level
5
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:26984196}. Host cytoplasm, host cytosol {ECO:0000269|PubMed:26984196}. Note=Is secreted into the cytosol of infected macrophages and is found in bronchoalveolar lavage samples of tuberculosis patients. Co-localizes with host tubulin. {ECO:0000269|PubMed:26984196}.
null
null
PF13740;PF21086;PF12710;
IPR045865;IPR002912;IPR050582;IPR036412;IPR023214;IPR004469;IPR049148;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
serB2 Rv3042c
false
Mycobacterium tuberculosis
644
row_5450
false
null
26,907
P9WKL1
MSNAPKIKVSGPVVELDGDEMTRVIWKLIKDMLILPYLDIRLDYYDLGIEHRDATDDQVTIDAAYAIKKHGVGVKCATITPDEARVEEFNLKKMWLSPNGTIRNILGGTIFREPIVISNVPRLVPGWTKPIVIGRHAFGDQYRATNFKVDQPGTVTLTFTPADGSAPIVHEMVSIPEDGGVVLGMYNFKESIRDFARASFSYGLNAKWPVYLSTKNTILKAYDGMFKDEFERVYEEEFKAQFEAAGLTYEHRLIDDMVAACLKWEGGYVWACKNYDGDVQSDTVAQGYGSLGLMTSVLMTADGKTVEAEAAHGTVTRHYRQYQAGKPTSTNPIASIFAWTRGLQHRGKLDGTPEVIDFAHKLESVVIATVESGKMTKDLAILIGPEQDWLNSEEFLDAIADNLEKELAN
Isocitrate dehydrogenase [NADP] 1 (ICD-1) (ICDH-1) (IDH 1) (EC 1.1.1.42) (IDP) (NADP(+)-specific ICDH) (Oxalosuccinate decarboxylase)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
409
45,514
3D-structure;Acetylation;Glyoxylate bypass;Magnesium;Manganese;Metal-binding;NADP;Oxidoreductase;Reference proteome;Tricarboxylic acid cycle
GO:0000287; GO:0004450; GO:0005886; GO:0006097; GO:0006099; GO:0006102; GO:0008270; GO:0051287
Evidence at protein level
5
null
null
null
PF00180;
IPR019818;IPR004790;IPR024084;
4HCX;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
icd-1 icd Rv3339c MTV016.39c
false
Mycobacterium tuberculosis
645
row_23548
false
null
430,691
P95280
MDVSYPPEAEAFRDRIREFVAEHLPPGWPGPGALPPHEREEFARHWRRALAGAGLVAVSWPTEYGGGGLSPMEQVVLAEEFARAGAPERAENDLLGIDLLGNTLIALGSEAQKRHFLPRILSGEHRWCQGFSEPEAGSDLASVRTRGVLDGDEWVINGHKIWTSAGTTANWIFLLARTDPSAAKHRGLSFLLVPMDQPGVVVRPIVNAAGHSSFSEVFLTDARTSAGNVVGRVGDGWSTAMTLLGFERGSHIATAAIDFERDLQRLCELARDRGLHTDPRVRDGLAWCYARVQIMRYRGYRDLTLALTGRPPGAEAAITKVIWSEYFRRYTDLAVEILGLEALGPRGPGNGGARLVPEAGTPNSPACWMDELLYARAATIYAGSSQIQRNVIGERLLGLPKEPRPEVLC
Putative acyl-CoA dehydrogenase FadE17 (EC 1.3.99.-)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
409
44,684
FAD;Flavoprotein;Oxidoreductase;Reference proteome
GO:0009274; GO:0016627; GO:0050660
Evidence at transcript level
2
null
null
null
PF00441;PF02770;PF02771;
IPR006091;IPR046373;IPR036250;IPR009075;IPR013786;IPR037069;IPR009100;IPR052161;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
fadE17 Rv1934c
false
Mycobacterium tuberculosis
646
row_412453
false
null
544,731
P64962
MGANGDVALSRIGATRPALSAWRFVTVFGVVGLLADVVYEGARSITGPLLASLGATGLVVGVVTGVGEAAALGLRLVSGPLADRSRRFWAWTIAGYTLTVVTVPLLGIAGALWVACALVIAERVGKAVRGPAKDTLLSHAASVTGRGRGFAVHEALDQVGAMIGPLTVAGMLAITGNAYAPALGVLTLPGGAALALLLWLQRRVPRPESYEDCPVVLGNPSAPRPWALPAQFWLYCGFTAITMLGFGTFGLLSFHMVSHGVLAAAMVPVVYAAAMAADALTALASGFSYDRYGAKTLAVLPILSILVVLFAFTDNVTMVVIGTLVWGAAVGIQESTLRGVVADLVASPRRASAYGVFAAGLGAATAGGGALIGWLYDISIGTLVVVVIALELMALVMMFAIRLPRVAPS
Uncharacterized protein Mb2288
Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
233,413
409
41,890
Cell membrane;Membrane;Reference proteome;Transmembrane;Transmembrane helix
GO:0005886; GO:0022857
Predicted
1
SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
null
TRANSMEM 18..38; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 47..67; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 100..120; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 159..179; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 180..200; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 232..252; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 260..280; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 302..322; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 355..375; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 380..400; /note="Helical"; /evidence="ECO:0000255"
PF07690;
IPR011701;IPR036259;IPR052425;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype)
BQ2027_MB2288
false
Mycobacterium tuberculosis
647
row_524974
false
null
4,127
I6Y9J2
MPKVGIAAQAGRTRVRRAWLTALMMTAVMIGAVACGSGRGPAPIKVIADKGTPFADLLVPKLTASVTDGAVGVTVDAPVSVTAADGVLAAVTMVNDNGRPVAGRLSPDGLRWSTTEQLGYNRRYTLNATALGLGGAATRQLTFQTSSPAHLTMPYVMPGDGEVVGVGEPVAIRFDENIADRGAAEKAIKITTNPPVEGAFYWLNNREVRWRPEHFWKPGTAVDVAVNTYGVDLGEGMFGEDNVQTHFTIGDEVIATADDNTKILTVRVNGEVVKSMPTSMGKDSTPTANGIYIVGSRYKHIIMDSSTYGVPVNSPNGYRTDVDWATQISYSGVFVHSAPWSVGAQGHTNTSHGCLNVSPSNAQWFYDHVKRGDIVEVVNTVGGTLPGIDGLGDWNIPWDQWRAGNAKA
L,D-transpeptidase 2 (LDT 2) (EC 2.3.2.-) (Ldt(Mt2))
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
408
43,366
3D-structure;Acyltransferase;Calcium;Cell membrane;Cell shape;Cell wall biogenesis/degradation;Lipoprotein;Membrane;Metal-binding;Palmitate;Peptidoglycan synthesis;Reference proteome;Signal;Transferase
GO:0005886; GO:0008360; GO:0016746; GO:0018104; GO:0046872; GO:0071555; GO:0071972
Evidence at protein level
5
SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|PROSITE-ProRule:PRU00303}; Lipid-anchor {ECO:0000255|PROSITE-ProRule:PRU00303}.
SIGNAL 1..34; /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
null
PF17964;PF03734;
IPR041280;IPR050979;IPR005490;IPR038063;
3VYN;3VYO;3VYP;4GSQ;4GSR;4GSU;4HU2;4HUC;4QR7;4QRA;4QRB;4QTF;5D7H;5DC2;5DCC;5DU7;5DUJ;5DVP;5DZJ;5DZP;5E1G;5E1I;5K69;5LB1;5LBG;6IYV;6IYW;6LQB;6RLG;6RRM;7A0Z;7A10;7A11;7A1C;7A1E;7F71;7F8P;7KEM;8A1J;8A1K;8A1L;8A1M;8A1N;8A1O;8AHO;8BK3;8J65;8PXY;8PXZ;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
ldtB lppS Rv2518c RVBD_2518c P425_02624
false
Mycobacterium tuberculosis
648
row_3276
false
null
81,894
P9WNY9
MSVDDSADVVVVGAGPAGSAAAAWAARAGRDVLVIDTATFPRDKPCGDGLTPRAVAELHQLGLGKWLADHIRHRGLRMSGFGGEVEVDWPGPSFPSYGSAVARLELDDRIRKVAEDTGARMLLGAKAVAVHHDSSRRVVSLTLADGTEVGCRQLIVADGARSPLGRKLGRRWHRETVYGVAVRGYLSTAYSDDPWLTSHLELRSPDGAVLPGYGWIFPLGNGEVNIGVGALSTSRRPADLALRPLISYYTDLRRDEWGFTGQPRAVSSALLPMGGAVSGVAGSNWMLIGDAAACVNPLNGEGIDYGLETGRLAAELLDSRDLARLWPSLLADRYGRGFSVARRLALLLTFPRFLPTTGPITMRSTALMNIAVRVMSNLVTDDDRDWVARVWRGGGQLSRLVDRRPPFS
Menaquinone reductase (MK reductase) (EC 1.3.99.38)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
408
43,870
FAD;Flavoprotein;Menaquinone biosynthesis;Oxidoreductase;Reference proteome;Virulence
GO:0009234; GO:0009274; GO:0016627; GO:0016628; GO:0071949
Evidence at protein level
4
null
null
null
PF01494;
IPR002938;IPR036188;IPR011777;IPR050407;IPR054880;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
menJ Rv0561c
false
Mycobacterium tuberculosis
649
row_72334
false
null
410,024
P0A695
MDFGVLPPEINSGRMYAGPGSGPMMAAAAAWDSLAAELGLAAGGYRLAISELTGAYWAGPAAASMVAAVTPYVAWLSATAGQAEQAGMQARAAAAAYELAFAMTVPPPVVVANRALLVALVATNFFGQNTPAIAATEAQYAEMWAQDAAAMYAYAGSAAIATELTPFTAAPVTTSPAALAGQAAATVSSTVPPLATTAAVPQLLQQLSSTSLIPWYSALQQWLAENLLGLTPDNRMTIVRLLGISYFDEGLLQFEASLAQQAIPGTPGGAGDSGSSVLDSWGPTIFAGPRASPSVAGGGAVGGVQTPQPYWYWALDRESIGGSVSAALGKGSSAGSLSVPPDWAARARWANPAAWRLPGDDVTALRGTAENALLRGFPMASAGQSTGGGFVHKYGFRLAVMQRPPFAG
Uncharacterized PPE family protein PPE45
Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
233,413
408
41,469
Cell membrane;Membrane;Reference proteome;Transmembrane;Transmembrane helix
GO:0005886; GO:0052572
Inferred from homology
2
SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
null
TRANSMEM 56..76; /note="Helical"; /evidence="ECO:0000255"
PF00823;PF12484;
IPR022171;IPR000030;IPR038332;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype)
PPE45 BQ2027_MB2916C
false
Mycobacterium tuberculosis
650
row_392480
false
null
27,010
P9WPA3
MLRIGLTGGIGAGKSLLSTTFSQCGGIVVDGDVLAREVVQPGTEGLASLVDAFGRDILLADGALDRQALAAKAFRDDESRGVLNGIVHPLVARRRSEIIAAVSGDAVVVEDIPLLVESGMAPLFPLVVVVHADVELRVRRLVEQRGMAEADARARIAAQASDQQRRAVADVWLDNSGSPEDLVRRARDVWNTRVQPFAHNLAQRQIARAPARLVPADPSWPDQARRIVNRLKIACGHKALRVDHIGSTAVSGFPDFLAKDVIDIQVTVESLDVADELAEPLLAAGYPRLEHITQDTEKTDARSTVGRYDHTDSAALWHKRVHASADPGRPTNVHLRVHGWPNQQFALLFVDWLAANPGAREDYLTVKCDADRRADGELARYVTAKEPWFLDAYQRAWEWADAVHWRP
Dephospho-CoA kinase (EC 2.7.1.24) (Dephosphocoenzyme A kinase)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
407
44,669
ATP-binding;Coenzyme A biosynthesis;Cytoplasm;Kinase;Nucleotide-binding;Reference proteome;Transferase
GO:0002135; GO:0004140; GO:0005524; GO:0005829; GO:0015937; GO:0032564
Evidence at protein level
5
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00376}.
null
null
PF01121;PF04229;
IPR001977;IPR007344;IPR043519;IPR027417;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
coaE Rv1631 MTCY01B2.23
false
Mycobacterium tuberculosis
651
row_23649
false
null
81,669
P9WG31
MSGRHRKPTTSNVSVAKIAFTGAVLGGGGIAMAAQATAATDGEWDQVARCESGGNWSINTGNGYLGGLQFTQSTWAAHGGGEFAPSAQLASREQQIAVGERVLATQGRGAWPVCGRGLSNATPREVLPASAAMDAPLDAAAVNGEPAPLAPPPADPAPPVELAANDLPAPLGEPLPAAPADPAPPADLAPPAPADVAPPVELAVNDLPAPLGEPLPAAPADPAPPADLAPPAPADLAPPAPADLAPPAPADLAPPVELAVNDLPAPLGEPLPAAPAELAPPADLAPASADLAPPAPADLAPPAPAELAPPAPADLAPPAAVNEQTAPGDQPATAPGGPVGLATDLELPEPDPQPADAPPPGDVTEAPAETPQVSNIAYTKKLWQAIRAQDVCGNDALDSLAQPYVIG
Resuscitation-promoting factor RpfA (EC 3.-.-.-)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
407
39,975
Hydrolase;Reference proteome;Repeat;Signal;Virulence
GO:0005576; GO:0009372; GO:0010629; GO:0016787; GO:0042127
Evidence at protein level
4
null
SIGNAL 1..33; /evidence="ECO:0000255"
null
PF06737;
IPR023346;IPR010618;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
rpfA Rv0867c MTV043.60c
false
Mycobacterium tuberculosis
652
row_72118
false
null
181,638
I6XHJ3
MPRVDDDAVGVPLTGNGRGAVMTEAYVIDAVRTAVGKRGGALAGIHPVDLGALAWRGLLDRTDIDPAAVDDVIAGCVDAIGGQAGNIARLSWLAAGYPEEVPGVTVDRQCGSSQQAISFGAQAIMSGTADVIVAGGVQNMSQIPISSAMTVGEQFGFTSPTNESKQWLHRYGDQEISQFRGSELIAEKWNLSREEMERYSLTSHERAFAAIRAGHFENEIITVETESGPFRVDEGPRESSLEKMAGLQPLVEGGRLTAAMASQISDGASAVLLASERAVKDHGLRPRARIHHISARAADPVFMLTGPIPATRYALDKTGLAIDDIDTVEINEAFAPVVMAWLKEIKADPAKVNPNGGAIALGHPLGATGAKLFTTMLGELERIGGRYGLQTMCEGGGTANVTIIERL
Steroid 3-ketoacyl-CoA thiolase FadA6 (EC 2.3.1.16) (Acetyl-CoA acetyltransferase FadA6)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
407
42,981
Acyltransferase;Cholesterol metabolism;Direct protein sequencing;Lipid metabolism;Reference proteome;Steroid metabolism;Sterol metabolism;Transferase
GO:0003988; GO:0006707
Evidence at protein level
3
null
null
null
PF02803;PF00108;
IPR002155;IPR016039;IPR020617;IPR020613;IPR020616;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
fadA6 Rv3556c
false
Mycobacterium tuberculosis
653
row_168684
false
null
213,198
P9WQ82
MIPNPLEELTLEQLRSQRTSMKWRAHPADVLPLWVAEMDVKLPPTVADALRRAIDDGDTGYPYGTEYAEAVREFACQRWQWHDLEVSRTAIVPDVMLGIVEVLRLITDRGDPVIVNSPVYAPFYAFVSHDGRRVIPAPLRGDGRIDLDALQEAFSSARASSGSSGNVAYLLCNPHNPTGSVHTADELRGIAERAQRFGVRVVSDEIHAPLIPSGARFTPYLSVPGAENAFALMSASKAWNLGGLKAALAIAGREAAADLARMPEEVGHGPSHLGVIAHTAAFRTGGNWLDALLRGLDHNRTLLGALVDEHLPGVQYRWPQGTYLAWLDCRELGFDDAASDEMTEGLAVVSDLSGPARWFLDHARVALSSGHVFGIGGAGHVRINFATSRAILIEAVSRMSRSLLERR
Putative cystathionine beta-lyase (CBL) (EC 4.4.1.13) (Beta-cystathionase) (Cysteine lyase) (Cysteine-S-conjugate beta-lyase)
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
83,331
407
44,283
Amino-acid biosynthesis;Lyase;Methionine biosynthesis;Pyridoxal phosphate;Reference proteome
GO:0009086; GO:0030170; GO:0047804
Inferred from homology
3
null
null
null
PF00155;
IPR004839;IPR051798;IPR015424;IPR015421;IPR015422;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
MT2351
false
Mycobacterium tuberculosis
654
row_199396
false
null
430,860
P96831
MDFAMSAKAIDYRTRLSDFMTEHVFGAEADYDDYRRAAGPADHTAPPIIEELKTKAKDRGLWNLFLSAESGLTNLEYAPLAEMTGWSMEIAPEALNCAAPDTGNMEILHMFGTEQQRAQWLRPLLDGKIRSAFSMTEPAVASSDARNIETTISRDGADYVINGRKWWTSGAADPRCKILIVMGRTNPDAAAHQQQSMVLVPIDTPGVTIVRSTPVFGWQDRHGHCEIDYHNVRVPATNLLGEEGSGFAIAQARLGPGRIHHCMRALGAAERALALMVNRVRNRVAFGRPLAEQGVVQQAIAQSRNEIDQARLLCEKAAWTIDQHGNKEARHLVAMIKAVAPRVACDVIDRAIQVHGAAGVSDDTPLARLYGWHRAMRIFDGPDEVHLRSIARAELSREKSTFAAAVT
Probable acyl-CoA dehydrogenase FadE2 (EC 1.3.99.-)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
407
44,808
Direct protein sequencing;FAD;Flavoprotein;Oxidoreductase;Reference proteome
GO:0003995; GO:0005737; GO:0005886; GO:0033539; GO:0050660
Evidence at protein level
2
null
null
null
PF00441;PF02770;
IPR050741;IPR006091;IPR046373;IPR036250;IPR009075;IPR037069;IPR009100;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
fadE2 Rv0154c
false
Mycobacterium tuberculosis
655
row_412622
false
null
539,505
P0A5G2
MTDDHPRADIVSRQYHRWLYPHPIADLEAWTTANWEWFDPVHSHRILWPDREYRPDLDILIAGCGTNQAAIFAFTNRAAKVVAIDISRPALDHQQYLKDKHGLANLELHLLPIEELATLGRDFDLVVSTGVLHHLADPRAGMKELAHCLRRDGVVAAMLYGKYGRIGVELLGSVFRDLGLGQDDASIKLAKEAISLLPTYHPLRNYLTKARDLLSDSALVDTFLHGRQRSYTVEECVDLVTSAGLVFQGWFHKAPYYPHDFFVPNSEFYAAVNTLPEVKAWSVMERLETLNATHLFMACRRDRPKEQYTIDFSTVAALDYVPLMRTRCGVSGTDMFWPGWRMAPSPAQLAFLQQVDGRRTIREIAGCVARTGEPSGGSLADLEEFGRKLFQSLWRLDFVAVALPASG
Uncharacterized protein Mb2093c
Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
233,413
407
45,930
Reference proteome
null
Predicted
1
null
null
null
PF08242;
IPR013217;IPR029063;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype)
BQ2027_MB2093C
false
Mycobacterium tuberculosis
656
row_519794
false
null
539,510
P0A5H2
MRILAMTRAHNAGRTLAATLDSLAVFSDDIYVIDDRSTDDTAEILANHPAVTNVVRARPDLPPTPWLIPESAGLELLYRMADFCRPDWVMMVDADWLVETDIDLRAVLARTPDDIVALMCPMVSRWDDPEYPDLIPVMGTAEALRGPLWRWYPGLRAGGKLMHNPHWPANITDHGRIGQLPGVRLVHSGWSTLAERILRVEHYLRLDPDYRFNFGVAYDRSLLFGYALDEVDLLKADYRRRIRGDFDPLEPGGRLPIDREPRAIGRGYGPHAGGFHPGVDFATDPGTPVYAVASGAVSAIDEVDGLVSLTIARCELDVVYVFRPGDEGRLVLGDRIAAGAQLGTIGAQGESADGYLHFEVRTQDGHVNPVRYLANMGLRPWPPPGRLRAVSGSYPPATPCTITAEDR
Uncharacterized protein Mb3815c
Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
233,413
407
44,944
Reference proteome;Signal
GO:0004222
Inferred from homology
1
null
SIGNAL 1..27; /evidence="ECO:0000255"
null
PF13704;PF01551;
IPR050570;IPR011055;IPR029044;IPR016047;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype)
BQ2027_MB3815C
false
Mycobacterium tuberculosis
657
row_519799
false
null
81,491
P95251
MASVAQPVRRRPKDRKKQILDQAVGLFIERGFHSVKLEDIAEAAGVTARALYRHYDNKQALLAEAIRTGQDQYQSARRLTEGETEPTPRPLNADLEDLIAAAVASRALTVLWQREARYLNEDDRTAVRRRINAIVAGMRDSVLLEVPDLSPQHSELRAWAVSSTLTSLGRHSLSLPGEELKKLLYQACMAAARTPPVCELPPLPAGDAARDEADVLFSRYETLLAAGARLFRAQGYPAVNTSEIGKGAGIAGPGLYRSFSSKQAILDALIRRLDEWRCLECIRALRANQQAAQRLRGLVQGHVRISLDAPDLVAVSVTELSHASVEVRDGYLRNQGDREAVWIDLIGKLVPATSVAQGRLLVAAAISFIEDVARTWHLTRYAGVADEISGLALAILTSGAGNLLRA
Transcriptional repressor Mce3R (TetR family transcriptional regulator)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
406
44,342
3D-structure;DNA-binding;Lipid degradation;Lipid metabolism;Reference proteome;Repeat;Repressor;Transcription;Transcription regulation
GO:0000976; GO:0003677; GO:0003700; GO:0006355; GO:0016042; GO:0019216; GO:0045892
Evidence at protein level
4
null
null
null
PF00440;
IPR009057;IPR050109;IPR001647;
9B7Y;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
mce3R Rv1963c
false
Mycobacterium tuberculosis
658
row_71965
false
null
181,882
L7N653
MPSPRREDGDALRCGDRSAAVTEIRAALTALGMLDHQEEDLTTGRNVALELFDAQLDQAVRAFQQHRGLLVDGIVGEATYRALKEASYRLGARTLYHQFGAPLYGDDVATLQARLQDLGFYTGLVDGHFGLQTHNALMSYQREYGLAADGICGPETLRSLYFLSSRVSGGSPHAIREEELVRSSGPKLSGKRIIIDPGRGGVDHGLIAQGPAGPISEADLLWDLASRLEGRMAAIGMETHLSRPTNRSPSDAERAATANAVGADLMISLRCETQTSLAANGVASFHFGNSHGSVSTIGRNLADFIQREVVARTGLRDCRVHGRTWDLLRLTRMPTVQVDIGYITNPHDRGMLVSTQTRDAIAEGILAAVKRLYLLGKNDRPTGTFTFAELLAHELSVERAGRLGGS
N-acetylmuramoyl-L-alanine amidase CwlM (EC 3.5.1.28) (Peptidoglycan hydrolase CwlM)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
406
43,912
Cell wall biogenesis/degradation;Hydrolase;Periplasm;Reference proteome;Repeat
GO:0008745; GO:0009253; GO:0016998; GO:0042597; GO:0071555
Evidence at protein level
3
SUBCELLULAR LOCATION: Periplasm {ECO:0000305|PubMed:15680239}.
null
null
PF01520;PF01471;
IPR051922;IPR002508;IPR002477;IPR036365;IPR036366;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
cwlM Rv3915
false
Mycobacterium tuberculosis
659
row_168919
false
null
212,393
P9WGB4
MTDESSVRTPKALPDGVSQATVGVRGGMLRSGFEETAEAMYLTSGYVYGSAAVAEKSFAGELDHYVYSRYGNPTVSVFEERLRLIEGAPAAFATASGMAAVFTSLGALLGAGDRLVAARSLFGSCFVVCSEILPRWGVQTVFVDGDDLSQWERALSVPTQAVFFETPSNPMQSLVDIAAVTELAHAAGAKVVLDNVFATPLLQQGFPLGVDVVVYSGTKHIDGQGRVLGGAILGDREYIDGPVQKLMRHTGPAMSAFNAWVLLKGLETLAIRVQHSNASAQRIAEFLNGHPSVRWVRYPYLPSHPQYDLAKRQMSGGGTVVTFALDCPEDVAKQRAFEVLDKMRLIDISNNLGDAKSLVTHPATTTHRAMGPEGRAAIGLGDGVVRISVGLEDTDDLIADIDRALS
O-succinylhomoserine sulfhydrylase (OSH sulfhydrylase) (OSHS sulfhydrylase) (EC 2.5.1.-)
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
83,331
406
43,345
Amino-acid biosynthesis;Methionine biosynthesis;Pyridoxal phosphate;Reference proteome;Transferase
GO:0005737; GO:0016765; GO:0016846; GO:0019346; GO:0030170; GO:0071266; GO:0071268
Inferred from homology
3
null
null
null
PF01053;
IPR000277;IPR006234;IPR015424;IPR015421;IPR015422;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
metZ MT0402
false
Mycobacterium tuberculosis
660
row_198605
false
null
402,574
I6YET7
MTSTKVEDRVTAAVLGAIGHALALTASMTWEILWALILGFALSAVVQAVVRRSTIVTLLGDDRPRTLVIATGLGAASSSCSYAAVALARSLFRKGANFTAAMAFEIGSTNLVVELGIILALLMGWQFTAAEFVGGPIMILVLAVLFRLFVGARLIDAAREQAERGLAGSMEGHAAMDMSIKREGSFWRRLLSPPGFTSIAHVFVMEWLAILRDLILGLLIAGAIAAWVPESFWQSFFLANHPAWSAVWGPIIGPIVAIVSFVCSIGNVPLAAVLWNGGISFGGVIAFIFADLLILPILNIYRKYYGARMMLVLLGTFYASMVVAGYLIELLFGTTNLIPSQRSATVMTAEISWNYTTWLNVIFLVIAAALVVRFITSGGLPMLRMMGGSPDAPHDHHDRHDDHLGH
Putative permease Rv2963
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
406
43,729
Cell membrane;Membrane;Reference proteome;Transmembrane;Transmembrane helix
GO:0005886
Evidence at protein level
2
SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000255}.
null
TRANSMEM 30..50; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 67..87; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 111..131; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 132..152; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 208..228; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 246..266; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 278..298; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 312..332; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 361..381; /note="Helical"; /evidence="ECO:0000255"
PF03773;
IPR005524;IPR053166;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
Rv2963 RVBD_2963 P425_03084
false
Mycobacterium tuberculosis
661
row_385112
false
null
431,635
P9WJE2
MKAQRSFGLALSWPRVTAVFLVDVLILAVASHCPDSWQADHHVAWWVGVGVAAVVTLLSVVSYHGITVISGLATWVRDWSADPGTTLGAGCTPAIDHQRRFGRDTVGVREYNGRLVSVIEVTCGESGPSGRHWHRKSPVPMLPVVAVADGLRQFDIHLDGIDIVSVLVRGGVDAAKASASLQEWEPQGWKSEERAGDRTVADRRRTWLVLRMNPQRNVAAVACRDSLASTLVAATERLVQDLDGQSCAARPVTADELTEVDSAVLADLEPTWSRPGWRHLKHFNGYATSFWVTPSDITSETLDELCLPDSPEVGTTVVTVRLTTRVGSPALSAWVRYHSDTRLPKEVAAGLNRLTGRQLAAVRASLPAPTHRPLLVIPSRNLRDHDELVLPVGQELEHATSSFVGQ
ESX-5 secretion system protein EccE5 (ESX conserved component E5) (Type VII secretion system protein EccE5) (T7SS protein EccE5)
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
83,331
406
44,178
Cell inner membrane;Cell membrane;Membrane;Reference proteome;Transmembrane;Transmembrane helix;Transport
GO:0005886
Inferred from homology
2
SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250|UniProtKB:B2HSU8}; Multi-pass membrane protein {ECO:0000255}.
null
TRANSMEM 9..29; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 43..63; /note="Helical"; /evidence="ECO:0000255"
PF11203;
IPR050051;IPR021368;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
eccE5 MT1846
false
Mycobacterium tuberculosis
662
row_413393
false
null
546,491
P9WHX8
MFMDFAMLPPEVNSTRMYSGPGAGSLWAAAAAWDQVSAELQSAAETYRSVIASLTGWQWLGPSSVRMGAAVTPYVEWLTTTAAQARQTATQITAAATGFEQAFAMTVPPPAIMANRAQVLSLIATNFFGQNTAAIAALETQYAEMWEQDATAMYDYAATSAAARTLTPFTSPQQDTNSAGLPAQSAEVSRATANAGAADGNWLGNLLEEIGILLLPIAPELTPFFLEAGEIVNAIPFPSIVGDEFCLLDGLLAWYATIGSINNINSMGTGIIGAEKNLGILPELGSAAAAAAPPPADIAPAFLAPLTSMAKSLSDGALRGPGEVSAAMRGAGTIGQMSVPPAWKAPAVTTVRAFDATPMTTLPGGDAPAAGVPGLPGMPASGAGRAGVVPRYGVRLTVMTRPLSGG
Uncharacterized PPE family protein PPE61
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
83,331
406
41,549
Reference proteome
GO:0052572
Inferred from homology
1
null
null
null
PF00823;PF12484;
IPR022171;IPR000030;IPR038332;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
PPE61 MT3636
false
Mycobacterium tuberculosis
663
row_526586
false
null
69,173
O53380
MAFLRSVSCLAAAVFAVGTGIGLPTAAGEPNAAPAACPYKVSTPPAVDSSEVPAAGEPPLPLVVPPTPVGGNALGGCGIITAPGSAPAPGDVSAEAWLVADLDSGAVIAARDPHGRHRPASVIKVLVAMASINTLTLNKSVAGTADDAAVEGTKVGVNTGGTYTVNQLLHGLLMHSGNDAAYALARQLGGMPAALEKINLLAAKLGGRDTRVATPSGLDGPGMSTSAYDIGLFYRYAWQNPVFADIVATRTFDFPGHGDHPGYELENDNQLLYNYPGALGGKTGYTDDAGQTFVGAANRDGRRLMTVLLHGTRQPIPPWEQAAHLLDYGFNTPAGTQIGTLIEPDPSLMSTDRNPADRQRVDPQAAARISAADALPVRVGVAVIGALIVFGLIMVARAMNRRPQH
D-alanyl-D-alanine carboxypeptidase DacB1 (D,D-carboxypeptidase DacB1) (DD-carboxypeptidase) (DD-peptidase) (EC 3.4.16.-)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
405
41,682
3D-structure;Carboxypeptidase;Cell membrane;Cell shape;Cell wall biogenesis/degradation;Hydrolase;Membrane;Peptidoglycan synthesis;Phosphoprotein;Protease;Reference proteome;Signal;Transmembrane;Transmembrane helix
GO:0005886; GO:0006508; GO:0008360; GO:0009002; GO:0009252; GO:0071555
Evidence at protein level
4
SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000255}.
SIGNAL 1..32; /evidence="ECO:0000255"
TRANSMEM 375..395; /note="Helical"; /evidence="ECO:0000255"
PF00768;
IPR012338;IPR018044;IPR001967;
4PPR;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
dacB1 Rv3330
false
Mycobacterium tuberculosis
664
row_60174
false
null
81,923
P9WPN5
MTSVMSHEFQLATAETWPNPWPMYRALRDHDPVHHVVPPQRPEYDYYVLSRHADVWSAARDHQTFSSAQGLTVNYGELEMIGLHDTPPMVMQDPPVHTEFRKLVSRGFTPRQVETVEPTVRKFVVERLEKLRANGGGDIVTELFKPLPSMVVAHYLGVPEEDWTQFDGWTQAIVAANAVDGATTGALDAVGSMMAYFTGLIERRRTEPADDAISHLVAAGVGADGDTAGTLSILAFTFTMVTGGNDTVTGMLGGSMPLLHRRPDQRRLLLDDPEGIPDAVEELLRLTSPVQGLARTTTRDVTIGDTTIPAGRRVLLLYGSANRDERQYGPDAAELDVTRCPRNILTFSHGAHHCLGAAAARMQCRVALTELLARCPDFEVAESRIVWSGGSYVRRPLSVPFRVTS
Cytochrome P450 130 (EC 1.14.-.-)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
405
44,581
3D-structure;Heme;Iron;Metal-binding;Monooxygenase;Oxidoreductase;Reference proteome
GO:0005506; GO:0006707; GO:0008395; GO:0009274; GO:0020037; GO:0036199
Evidence at protein level
4
null
null
null
PF00067;
IPR001128;IPR002397;IPR017972;IPR036396;
2UUQ;2UVN;2WGY;2WH8;2WHF;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
cyp130 Rv1256c MTCY50.26
false
Mycobacterium tuberculosis
665
row_72361
false
null
431,672
P9WJQ4
MRSVQEHQRVVAEMMRACRPITVPLTQAQGLVLGGDVVAPLSLPVFDNSAMDGYAVRAEDTSGATPQNPVMLPVAEDIPAGRADMLTLQPVTAHRIMTGAPVPTGATAIVPVEATDGGVDSVAIRQQATPGKHIRRSGEDVAAGTTVLHNGQIVTPAVLGLAAALGLAELPVLPRQRVLVISTGSELASPGTPLQPGQIYESNSIMLAAAVRDAGAAVVATATAGDDVAQFGAILDRYAVDADLIITSGGVSAGAYEVVKDAFGSADYRGGDHGVEFVKVAMQPGMPQGVGRVAGTPIVTLPGNPVSALVSFEVFIRPPLRMAMGLPDPYRPHRSAVLTASLTSPRGKRQFRRAILDHQAGTVISYGPPASHHLRWLASANGLLDIPEDVVEVAAGTQLQVWDLT
Molybdopterin molybdenumtransferase 2 (MPT Mo-transferase 2) (EC 2.10.1.1)
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
83,331
405
42,021
Magnesium;Metal-binding;Molybdenum;Molybdenum cofactor biosynthesis;Reference proteome;Transferase
GO:0005829; GO:0006777; GO:0046872; GO:0061599
Inferred from homology
2
null
null
null
PF00994;PF03454;PF03453;
IPR036425;IPR001453;IPR038987;IPR005111;IPR036688;IPR005110;IPR036135;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
moaE2 MT0454
false
Mycobacterium tuberculosis
666
row_413430
false
null
26,796
P9WHS3
MMFVTGIVLFALAILISVALHECGHMWVARRTGMKVRRYFVGFGPTLWSTRRGETEYGVKAVPLGGFCDIAGMTPVEELDPDERDRAMYKQATWKRVAVLFAGPGMNLAICLVLIYAIALVWGLPNLHPPTRAVIGETGCVAQEVSQGKLEQCTGPGPAALAGIRSGDVVVKVGDTPVSSFDEMAAAVRKSHGSVPIVVERDGTAIVTYVDIESTQRWIPNGQGGELQPATVGAIGVGAARVGPVRYGVFSAMPATFAVTGDLTVEVGKALAALPTKVGALVRAIGGGQRDPQTPISVVGASIIGGDTVDHGLWVAFWFFLAQLNLILAAINLLPLLPFDGGHIAVAVFERIRNMVRSARGKVAAAPVNYLKLLPATYVVLVLVVGYMLLTVTADLVNPIRLFQ
Zinc metalloprotease Rip1 (EC 3.4.24.-) (Regulator of sigma KLM proteases) (S2P endopeptidase) (Site-2 protease Rip1) (S2P protease Rip1) (Site-2-type intramembrane protease)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
404
42,834
Cell membrane;Hydrolase;Membrane;Metal-binding;Metalloprotease;Protease;Reference proteome;Transmembrane;Transmembrane helix;Zinc
GO:0004175; GO:0004222; GO:0005886; GO:0006508; GO:0046872
Evidence at protein level
5
SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
null
TRANSMEM 1..21; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 104..124; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 313..333; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 373..393; /note="Helical"; /evidence="ECO:0000255"
PF17820;PF02163;
IPR001478;IPR041489;IPR036034;IPR004387;IPR008915;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
rip1 Rv2869c MTV003.15c
false
Mycobacterium tuberculosis
667
row_23442
false
null
27,044
P9WPZ3
MTDLAGTTRLLRAQGVTAPAGFRAAGVAAGIKASGALDLALVFNEGPDYAAAGVFTRNQVKAAPVLWTQQVLTTGRLRAVILNSGGANACTGPAGFADTHATAEAVAAALSDWGTETGAIEVAVCSTGLIGDRLPMDKLLAGVAHVVHEMHGGLVGGDEAAHAIMTTDNVPKQVALHHHDNWTVGGMAKGAGMLAPSLATMLCVLTTDAAAEPAALERALRRAAAATFDRLDIDGSCSTNDTVLLLSSGASEIPPAQADLDEAVLRVCDDLCAQLQADAEGVTKRVTVTVTGAATEDDALVAARQIARDSLVKTALFGSDPNWGRVLAAVGMAPITLDPDRISVSFNGAAVCVHGVGAPGAREVDLSDADIDITVDLGVGDGQARIRTTDLSHAYVEENSAYSS
Arginine biosynthesis bifunctional protein ArgJ [Cleaved into: Arginine biosynthesis bifunctional protein ArgJ alpha chain; Arginine biosynthesis bifunctional protein ArgJ beta chain] [Includes: Glutamate N-acetyltransferase (EC 2.3.1.35) (Ornithine acetyltransferase) (OATase) (Ornithine transacetylase); Amino-acid acetyltransferase (EC 2.3.1.1) (N-acetylglutamate synthase) (AGSase)]
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
404
41,147
3D-structure;Acyltransferase;Amino-acid biosynthesis;Arginine biosynthesis;Autocatalytic cleavage;Cytoplasm;Multifunctional enzyme;Reference proteome;Transferase
GO:0004042; GO:0004358; GO:0005737; GO:0006526; GO:0006592
Evidence at protein level
5
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01106, ECO:0000305}.
null
null
PF01960;
IPR002813;IPR016117;IPR042195;
3IT4;3IT6;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
argJ Rv1653 MTCY06H11.18
false
Mycobacterium tuberculosis
668
row_23683
false
null
67,981
O07801
MKCPGVSDCVATVRHDNVFAIAAGLRWSAAVPPLHKGDAVTKLLVGAIAGGMLACAAILGDGIASADTALIVPGTAPSPYGPLRSLYHFNPAMQPQIGANYYNPTATRHVVSYPGSFWPVTGLNSPTVGSSVSAGTNNLDAAIRSTDGPIFVAGLSQGTLVLDREQARLANDPTAPPPGQLTFIKAGDPNNLLWRAFRPGTHVPIIDYTVPAPAESQYDTINIVGQYDIFSDPPNRPGNLLADLNAIAAGGYYGHSATAFSDPARVAPRDITTTTNSLGATTTTYFIRTDQLPLVRALVDMAGLPPQAAGTVDAALRPIIDRAYQPGPAPAVNPRDLVQGIRGIPAIAPAIAIPIGSTTGASAATSTAAATAAATNALRGANVGPGANKALSMVRGLLPKGKKH
SL1278 acyltransferase Chp1 (EC 2.3.1.284) (Cutinase-like hydrolase protein)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
404
41,408
Acyltransferase;Cell inner membrane;Cell membrane;Lipid biosynthesis;Lipid metabolism;Membrane;Reference proteome;Transferase;Transmembrane;Transmembrane helix
GO:0005886; GO:0006629; GO:0016746
Evidence at protein level
4
SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000269|PubMed:22194604}; Single-pass membrane protein {ECO:0000255}. Note=The catalytic site is on the cytoplasmic side of the inner membrane. {ECO:0000269|PubMed:22194604}.
null
TRANSMEM 43..63; /note="Helical"; /evidence="ECO:0000255"
PF08237;
IPR029058;IPR013228;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
chp1 Rv3822 RVBD_3822 P425_03980
false
Mycobacterium tuberculosis
669
row_59073
false
null
81,851
P9WMW5
MQYGLEVSSDVAGVAGGLLALSYRGAGVPLRELALVGLTAAIITYFATGPVRMLASRLGAVAYPRERDVHVTPTPRMGGLAMFLGIVGAVFLASQLPALTRGFVYSTGMPAVLVAGAVIMGIGLIDDRWGLDALTKFAGQITAASVLVTMGVAWSVLYIPVGGVGTIVLDQASSILLTLALTVSIVNAMNFVDGLDGLAAGLGLITALAICMFSVGLLRDHGGDVLYYPPAVISVVLAGACLGFLPHNFHRAKIFMGDSGSMLIGLMLAAASTTAAGPISQNAYGARDVFALLSPFLLVVAVMFVPMLDLLLAIVRRTRAGRSAFSPDKMHLHHRLLQIGHSHRRVVLIIYLWVGIVAFGAASSIFFNPRDTAAVMLGAIVVAGVATLIPLLRRGDDYYDPDLD
Decaprenyl-phosphate N-acetylglucosaminephosphotransferase (EC 2.7.8.35) (Decaprenyl-phosphate GlcNAc-1-phosphate transferase) (Decaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase) (UDP-GlcNAc:decaprenyl-phosphate GlcNAc-1-phosphate transferase)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
404
42,257
Cell membrane;Cell wall biogenesis/degradation;Glycosyltransferase;Magnesium;Manganese;Membrane;Reference proteome;Transferase;Transmembrane;Transmembrane helix
GO:0000287; GO:0005886; GO:0009103; GO:0016757; GO:0016780; GO:0030145; GO:0044038; GO:0045227; GO:0071555
Evidence at protein level
4
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
null
TRANSMEM 33..53; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 79..99; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 105..125; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 148..168; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 175..195; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 198..218; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 225..245; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 259..279; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 295..315; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 347..367; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 372..392; /note="Helical"; /evidence="ECO:0000255"
PF00953;
IPR000715;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
wecA rfe Rv1302 MTCY373.22
false
Mycobacterium tuberculosis
670
row_72295
false
null
81,858
P9WN43
MREVPHVLGIVLAGGEGKRLYPLTADRAKPAVPFGGAYRLIDFVLSNLVNARYLRICVLTQYKSHSLDRHISQNWRLSGLAGEYITPVPAQQRLGPRWYTGSADAIYQSLNLIYDEDPDYIVVFGADHVYRMDPEQMVRFHIDSGAGATVAGIRVPRENATAFGCIDADDSGRIRSFVEKPLEPPGTPDDPDTTFVSMGNYIFTTKVLIDAIRADADDDHSDHDMGGDIVPRLVADGMAAVYDFSDNEVPGATDRDRAYWRDVGTLDAFYDAHMDLVSVHPVFNLYNKRWPIRGESENLAPAKFVNGGSAQESVVGAGSIISAASVRNSVLSSNVVVDDGAIVEGSVIMPGTRVGRGAVVRHAILDKNVVVGPGEMVGVDLEKDRERFAISAGGVVAVGKGVWI
Glucose-1-phosphate adenylyltransferase (EC 2.7.7.27) (ADP-glucose pyrophosphorylase) (ADPGlc PPase) (ADP-glucose synthase)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
404
43,800
ATP-binding;Capsule biogenesis/degradation;Carbohydrate metabolism;Glycogen biosynthesis;Glycogen metabolism;Nucleotide-binding;Nucleotidyltransferase;Reference proteome;Transferase
GO:0005524; GO:0005829; GO:0005978; GO:0008878; GO:0009250; GO:0045227
Evidence at protein level
4
null
null
null
PF24894;PF00483;
IPR011831;IPR005836;IPR023049;IPR056818;IPR005835;IPR029044;IPR011004;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
glgC Rv1213 MTCI364.25
false
Mycobacterium tuberculosis
671
row_72302
false
null
81,520
P96402
MNQRRAAGSTGVAYIRWLLRARPADYMLALSVAGGSLPVVGKHLKPLGGVTAIGVWGARHASDFLSATAKDLLTPGINEVRRRDRASTQEVSVAALRGIVSPDDLAVEWPAPERTPPVCGALRHRRYVHRRRVLYGDDPAQLLDVWRRKDMPTKPAPVLIFVPGGAWVHGSRAIQGYAVLSRLAAQGWVCLSIDYRVAPHHRWPRHILDVKTAIAWARANVDKFGGDRNFIAVAGCSAGGHLSALAGLTANDPQYQAELPEGSDTSVDAVVGIYGRYDWEDRSTPERARFVDFLERVVVQRTIDRHPEVFRDASPIQRVTRNAPPFLVIHGSRDCVIPVEQARSFVERLRAVSRSQVGYLELPGAGHGFDLLDGARTGPTAHAIALFLNQVHRSRAQFAKEVI
Esterase LipC (EC 3.1.1.-)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
403
44,308
Cell wall;Hydrolase;Reference proteome;Secreted
GO:0004806; GO:0005576; GO:0008126; GO:0009986; GO:0042603; GO:0046503
Evidence at protein level
4
SUBCELLULAR LOCATION: Cell surface {ECO:0000269|PubMed:22038913}. Secreted, cell wall {ECO:0000269|PubMed:22038913}. Secreted, capsule {ECO:0000269|PubMed:22038913}. Note=Cell surface protein that is present in both the cell wall and the capsule. {ECO:0000269|PubMed:22038913}.
null
null
PF20434;
IPR029058;IPR049492;IPR019826;IPR050300;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
lipC Rv0220
false
Mycobacterium tuberculosis
672
row_71990
false
null
81,693
P9WGV1
MSEKGRLFTSESVTEGHPDKICDAISDSVLDALLAADPRSRVAVETLVTTGQVHVVGEVTTSAKEAFADITNTVRARILEIGYDSSDKGFDGATCGVNIGIGAQSPDIAQGVDTAHEARVEGAADPLDSQGAGDQGLMFGYAINATPELMPLPIALAHRLSRRLTEVRKNGVLPYLRPDGKTQVTIAYEDNVPVRLDTVVISTQHAADIDLEKTLDPDIREKVLNTVLDDLAHETLDASTVRVLVNPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMRWVAKNVVAAGLAERVEVQVAYAIGKAAPVGLFVETFGTETEDPVKIEKAIGEVFDLRPGAIIRDLNLLRPIYAPTAAYGHFGRTDVELPWEQLDKVDDLKRAI
S-adenosylmethionine synthase (AdoMet synthase) (EC 2.5.1.6) (MAT) (Methionine adenosyltransferase)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
403
43,047
3D-structure;ATP-binding;Cytoplasm;Isopeptide bond;Magnesium;Metal-binding;Nucleotide-binding;One-carbon metabolism;Potassium;Reference proteome;Transferase;Ubl conjugation
GO:0000287; GO:0004478; GO:0005524; GO:0005829; GO:0005886; GO:0006556; GO:0006730; GO:0009274; GO:0035375
Evidence at protein level
4
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00086}.
null
null
PF02773;PF02772;PF00438;
IPR022631;IPR022630;IPR022629;IPR022628;IPR002133;IPR022636;
3TDE;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
metK Rv1392 MTCY21B4.09
false
Mycobacterium tuberculosis
673
row_72142
false
null
185,410
O53871
MSEEAFIYEAIRTPRGKQKNGSLHEVKPLSLVVGLIDELRKRHPDLDENLISDVILGCVSPVGDQGGDIARAAVLASGMPVTSGGVQLNRFCASGLEAVNTAAQKVRSGWDDLVLAGGVESMSRVPMGSDGGAMGLDPATNYDVMFVPQSIGADLIATIEGFSREDVDAYALRSQQKAAEAWSGGYFAKSVVPVRDQNGLLILDHDEHMRPDTTKEGLAKLKPAFEGLAALGGFDDVALQKYHWVEKINHVHTGGNSSGIVDGAALVMIGSAAAGKLQGLTPRARIVATATSGADPVIMLTGPTPATRKVLDRAGLTVDDIDLFELNEAFASVVLKFQKDLNIPDEKLNVNGGAIAMGHPLGATGAMILGTMVDELERRNARRALITLCIGGGMGVATIIERV
Putative acyltransferase Rv0859 (EC 2.3.1.-)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
403
42,414
3D-structure;Acyltransferase;Isopeptide bond;Reference proteome;Transferase;Ubl conjugation
GO:0003985; GO:0005886; GO:0009274
Evidence at protein level
3
null
null
null
PF02803;PF00108;
IPR002155;IPR016039;IPR020615;IPR020610;IPR020617;IPR020613;IPR020616;
4B3H;4B3I;4B3J;7O1G;7O1I;7O1J;7O1K;7O1L;7O1M;7O4Q;7O4R;7O4S;7O4T;7O4V;8OPU;8OPV;8OPW;8OPX;8OPY;8OQL;8OQM;8OQN;8OQO;8OQP;8OQQ;8OQR;8OQS;8OQT;8OQU;8OQV;8PF8;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
fadA Rv0859
false
Mycobacterium tuberculosis
674
row_172369
false
null
26,710
P9WFK7
MTVTLCSPTEDDWPGMFLLAAASFTDFIGPESATAWRTLVPTDGAVVVRDGAGPGSEVVGMALYMDLRLTVPGEVVLPTAGLSFVAVAPTHRRRGLLRAMCAELHRRIADSGYPVAALHASEGGIYGRFGYGPATTLHELTVDRRFARFHADAPGGGLGGSSVRLVRPTEHRGEFEAIYERWRQQVPGGLLRPQVLWDELLAECKAAPGGDRESFALLHPDGYALYRVDRTDLKLARVSELRAVTADAHCALWRALIGLDSMERISIITHPQDPLPHLLTDTRLARTTWRQDGLWLRIMNVPAALEARGYAHEVGEFSTVLEVSDGGRFALKIGDGRARCTPTDAAAEIEMDRDVLGSLYLGAHRASTLAAANRLRTKDSQLLRRLDAAFASDVPVQTAFEF
N-acetyltransferase Eis (EC 2.3.1.-) (Aminoglycoside N-acetyltransferase) (Enhanced intracellular survival protein) (Protein-lysine N-acetyltransferase)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
402
43,804
3D-structure;Acyltransferase;Antibiotic resistance;Direct protein sequencing;Host cytoplasmic vesicle;Reference proteome;Secreted;Transferase
GO:0005829; GO:0008080; GO:0030649; GO:0033661; GO:0034069; GO:0042802; GO:0043655; GO:0044161; GO:0046677; GO:0051701; GO:0052032; GO:0052040; GO:0052041; GO:0052167; GO:0061733; GO:0097691
Evidence at protein level
5
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:11401966}. Host cytoplasmic vesicle, host phagosome {ECO:0000269|PubMed:17259625}. Extracellular vesicle, bacterial extracellular vesicle {ECO:0000269|PubMed:17259625}. Host extracellular space {ECO:0000269|PubMed:17259625}. Note=Eis is present in the macrophage cytoplasm from 4 to 96 hours post-infection. {ECO:0000269|PubMed:17259625}.
null
null
PF17668;PF13527;PF13530;
IPR041380;IPR051554;IPR016181;IPR025559;IPR000182;IPR022902;IPR036527;
3R1K;3RYO;3SXO;3UY5;4JD6;5EBV;5EC4;5IV0;5TVJ;6B0U;6B3T;6P3T;6P3U;6P3V;6VUR;6VUS;6VUT;6VUU;6VUW;6VUX;6VUY;6VUZ;6VV0;6VV1;6VV2;6VV3;6X10;6X6G;6X6I;6X6Y;6X7A;8D1R;8D23;8D25;8F4A;8F4T;8F4U;8F4W;8F4Z;8F51;8F55;8F57;8F58;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
eis Rv2416c MTCY253.04
false
Mycobacterium tuberculosis
675
row_23359
false
null
81,886
P9WNU1
MDAATTRVGLTDLTFRLLRESFADAVSWVAKNLPARPAVPVLSGVLLTGSDNGLTISGFDYEVSAEAQVGAEIVSPGSVLVSGRLLSDITRALPNKPVDVHVEGNRVALTCGNARFSLPTMPVEDYPTLPTLPEETGLLPAELFAEAISQVAIAAGRDDTLPMLTGIRVEILGETVVLAATDRFRLAVRELKWSASSPDIEAAVLVPAKTLAEAAKAGIGGSDVRLSLGTGPGVGKDGLLGISGNGKRSTTRLLDAEFPKFRQLLPTEHTAVATMDVAELIEAIKLVALVADRGAQVRMEFADGSVRLSAGADDVGRAEEDLVVDYAGEPLTIAFNPTYLTDGLSSLRSERVSFGFTTAGKPALLRPVSGDDRPVAGLNGNGPFPAVSTDYVYLLMPVRLPG
Beta sliding clamp (Beta clamp) (Sliding clamp) (Beta-clamp processivity factor) (DNA polymerase III beta sliding clamp subunit) (DNA polymerase III subunit beta) (Mtb beta-clamp)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
402
42,113
3D-structure;Antibiotic resistance;Cytoplasm;DNA replication;DNA-binding;DNA-directed DNA polymerase;Nucleotidyltransferase;Reference proteome;Transferase
GO:0003677; GO:0003887; GO:0005576; GO:0005737; GO:0006271; GO:0008408; GO:0009274; GO:0009360; GO:0042802; GO:0046677
Evidence at protein level
4
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:P0A988}.
null
null
PF00712;PF02767;PF02768;
IPR046938;IPR001001;IPR022635;IPR022637;IPR022634;
3P16;3RB9;5AGU;5AGV;6FVN;6FVO;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
dnaN Rv0002 MTCY10H4.0 MTV029.02
false
Mycobacterium tuberculosis
676
row_72326
false
null
213,168
P9WQ05
MGVELGSNSEVGALRVVILHRPGAELRRLTPRNTDQLLFDGLPWVSRAQDEHDEFAELLASRGAEVLLLSDLLTEALHHSGAARMQGIAAAVDAPRLGLPLAQELSAYLRSLDPGRLAHVLTAGMTFNELPSDTRTDVSLVLRMHHGGDFVIEPLPNLVFTRDSSIWIGPRVVIPSLALRARVREASLTDLIYAHHPRFTGVRRAYESRTAPVEGGDVLLLAPGVVAVGVGERTTPAGAEALARSLFDDDLAHTVLAVPIAQQRAQMHLDTVCTMVDTDTMVMYANVVDTLEAFTIQRTPDGVTIGDAAPFAEAAAKAMGIDKLRVIHTGMDPVVAEREQWDDGNNTLALAPGVVVAYERNVQTNARLQDAGIEVLTIAGSELGTGRGGPRCMSCPAARDPL
Arginine deiminase (ADI) (EC 3.5.3.6) (Arginine dihydrolase) (AD)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
402
43,089
Arginine metabolism;Cytoplasm;Hydrolase;Reference proteome
GO:0005737; GO:0005886; GO:0016990; GO:0019546; GO:0019547
Evidence at protein level
3
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
null
null
PF02274;
IPR003876;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
arcA Rv1001 MTCI237.16
false
Mycobacterium tuberculosis
677
row_199366
false
null
425,420
P63708
MTVRVGDPELVLDPYDYDFHEDPYPYYRRLRDEAPLYRNEERNFWAVSRHHDVLQGFRDSTALSNAYGVSLDPSSRTSEAYRVMSMLAMDDPAHLRMRTLVSKGFTPRRIRELEPQVLELARIHLDSALQTESFDFVAEFAGKLPMDVISELIGVPDTDRARIRALADAVLHREDGVADVPPPAMAASIELMRYYADLIAEFRRRPANNLTSALLAAELDGDRLSDQEIMAFLFLMVIAGNETTTKLLANAVYWAAHHPGQLARVFADHSRIPMWVEETLRYDTSSQILARTVAHDLTLYDTTIPEGEVLLLLPGSANRDDRVFDDPDDYRIGREIGCKLVSFGSGAHFCLGAHLARMEARVALGALLRRIRNYEVDDDNVVRVHSSNVRGFAHLPISVQAR
Putative cytochrome P450 123 (EC 1.14.-.-)
Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
233,413
402
45,421
Heme;Iron;Metal-binding;Monooxygenase;Oxidoreductase;Reference proteome
GO:0005506; GO:0006707; GO:0008395; GO:0020037; GO:0036199
Inferred from homology
2
null
null
null
PF00067;
IPR001128;IPR002397;IPR017972;IPR036396;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype)
cyp123 BQ2027_MB0789C
false
Mycobacterium tuberculosis
678
row_407521
false
null
431,630
P9WJD2
MASGSGLCKTTSNFIWGQLLLLGEGIPDPGDIFNTGSSLFKQISDKMGLAIPGTNWIGQAAEAYLNQNIAQQLRAQVMGDLDKLTGNMISNQAKYVSDTRDVLRAMKKMIDGVYKVCKGLEKIPLLGHLWSWELAIPMSGIAMAVVGGALLYLTIMTLMNATNLRGILGRLIEMLTTLPKFPGLPGLPSLPDIIDGLWPPKLPDIPIPGLPDIPGLPDFKWPPTPGSPLFPDLPSFPGFPGFPEFPAIPGFPALPGLPSIPNLFPGLPGLGDLLPGVGDLGKLPTWTELAALPDFLGGFAGLPSLGFGNLLSFASLPTVGQVTATMGQLQQLVAAGGGPSQLASMGSQQAQLISSQAQQGGQQHATLVSDKKEDEEGVAEAERAPIDAGTAASQRGQEGTVL
ESX-1 secretion-associated protein EspE
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
83,331
402
42,069
Cell membrane;Membrane;Reference proteome;Transmembrane;Transmembrane helix
GO:0005886
Inferred from homology
2
SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000255}.
null
TRANSMEM 136..156; /note="Helical"; /evidence="ECO:0000255"
PF18879;
IPR043796;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
espE MT3978
false
Mycobacterium tuberculosis
679
row_413388
false
null
27,041
P9WPY1
MLRWITAGESHGRALVAVVEGMVAGVHVTSADIADQLARRRLGYGRGARMTFERDAVTVLSGIRHGSTLGGPIAIEIGNTEWPKWETVMAADPVDPAELADVARNAPLTRPRPGHADYAGMLKYGFDDARPVLERASARETAARVAAGTVARAFLRQALGVEVLSHVISIGASAPYEGPPPRAEDLPAIDASPVRAYDKAAEADMIAQIEAAKKDGDTLGGVVEAVALGLPVGLGSFTSGDHRLDSQLAAAVMGIQAIKGVEIGDGFQTARRRGSRAHDEMYPGPDGVVRSTNRAGGLEGGMTNGQPLRVRAAMKPISTVPRALATVDLATGDEAVAIHQRSDVCAVPAAGVVVETMVALVLARAALEKFGGDSLAETQRNIAAYQRSVADREAPAARVSG
Chorismate synthase (CS) (EC 4.2.3.5) (5-enolpyruvylshikimate-3-phosphate phospholyase)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
401
41,792
3D-structure;Amino-acid biosynthesis;Aromatic amino acid biosynthesis;FAD;Flavoprotein;FMN;Lyase;NADP;Reference proteome
GO:0004107; GO:0005829; GO:0008652; GO:0009073; GO:0009423; GO:0010181; GO:0016651; GO:0051287
Evidence at protein level
5
null
null
null
PF01264;
IPR000453;IPR035904;IPR020541;
1ZTB;2G85;2O11;2O12;2QHF;4BAI;4BAJ;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
aroC aroF Rv2540c MTCY159.16
false
Mycobacterium tuberculosis
680
row_23680
false
null
547,006
P9WLZ2
MNLDGNQASIREVCDAGLLSGAVTMVWQREKLLQVNEIGYRDIDAGVPMQRDTLFRIASMTKPVTVAAAMSLVDEGKLALRDPITRWAPELCKVAVLDDAAGPLDRTHPARRAILIEDLLTHTSGLAYGFSVSGPISRAYQRLPFGQGPDVWLAALATLPLVHQPGDRVTYSHAIDVLGVIVSRIEDAPLYQIIDERVLGPAGMTDTGFYVSADAQRRAATMYRLDEQDRLRHDVMGPPHVTPPSFCNAGGGLWSTADDYLRFVRMLLGDGTVDGVRVLSPESVRLMRTDRLTDEQKRHSFLGAPFWVGRGFGLNLSVVTDPAKSRPLFGPGGLGTFSWPGAYGTWWQADPSADLILLYLIQHCPDLSVDAAAAVAGNPSLAKLRTAQPKFVRRTYRALGL
Uncharacterized protein MT1414
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
83,331
401
43,742
Reference proteome
null
Predicted
1
null
null
null
PF00144;
IPR001466;IPR012338;IPR050789;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
MT1414
false
Mycobacterium tuberculosis
681
row_527098
false
null
4,130
I6YCA3
MRISYTPQQEELRRELRSYFATLMTPERREALSSVQGEYGVGNVYRETIAQMGRDGWLALGWPKEYGGQGRSAMDQLIFTDEAAIAGAPVPFLTINSVAPTIMAYGTDEQKRFFLPRIAAGDLHFSIGYSEPGAGTDLANLRTTAVRDGDDYVVNGQKMWTSLIQYADYVWLAVRTNPESSGAKKHRGISVLIVPTTAEGFSWTPVHTMAGPDTSATYYSDVRVPVANRVGEENAGWKLVTNQLNHERVALVSPAPIFGCLREVREWAQNTKDAGGTRLIDSEWVQLNLARVHAKAEVLKLINWELASSQSGPKDAGPSPADASAAKVFGTELATEAYRLLMEVLGTAATLRQNSPGALLRGRVERMHRACLILTFGGGTNEVQRDIIGMVALGLPRANR
Acyl-CoA dehydrogenase FadE26 (ACAD) (EC 1.3.99.-) (3-oxocholest-4-en-26-oyl-CoA dehydrogenase alpha subunit)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
400
43,785
3D-structure;Cholesterol metabolism;FAD;Flavoprotein;Lipid degradation;Lipid metabolism;Oxidoreductase;Reference proteome;Steroid metabolism;Sterol metabolism;Virulence
GO:0006707; GO:0016627; GO:0050660
Evidence at protein level
5
null
null
null
PF00441;PF02770;PF02771;
IPR006091;IPR046373;IPR036250;IPR009075;IPR013786;IPR037069;IPR009100;IPR052161;
4X28;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
fadE26 Rv3504
false
Mycobacterium tuberculosis
682
row_3279
false
null
81,935
P9WPZ7
MTGASTTTATMRQRWQAVMMNNYGTPPIALASGDGAVVTDVDGRTYIDLLGGIAVNVLGHRHPAVIEAVTRQMSTLGHTSNLYATEPGIALAEELVALLGADQRTRVFFCNSGAEANEAAFKLSRLTGRTKLVAAHDAFHGRTMGSLALTGQPAKQTPFAPLPGDVTHVGYGDVDALAAAVDDHTAAVFLEPIMGESGVVVPPAGYLAAARDITARRGALLVLDEVQTGMGRTGAFFAHQHDGITPDVVTLAKGLGGGLPIGACLAVGPAAELLTPGLHGSTFGGNPVCAAAALAVLRVLASDGLVRRAEVLGKSLRHGIEALGHPLIDHVRGRGLLLGIALTAPHAKDAEATARDAGYLVNAAAPDVIRLAPPLIIAEAQLDGFVAALPAILDRAVGAP
Acetylornithine aminotransferase (ACOAT) (EC 2.6.1.11)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
400
40,910
3D-structure;Acetylation;Amino-acid biosynthesis;Aminotransferase;Arginine biosynthesis;Cytoplasm;Isopeptide bond;Pyridoxal phosphate;Reference proteome;Transferase;Ubl conjugation
GO:0003992; GO:0005737; GO:0006526; GO:0030170; GO:0042802
Evidence at protein level
4
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01107}.
null
null
PF00202;
IPR004636;IPR005814;IPR049704;IPR050103;IPR015424;IPR015421;IPR015422;
7NN1;7NN4;7NNC;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
argD Rv1655 MTCY06H11.20
false
Mycobacterium tuberculosis
683
row_72373
false
null
431,654
P9WJJ0
MTRVVVIGSGFAGLWAALGAARRLDELAVPAGTVDVMVVSNKPFHDIRVRNYEADLSACRIPLGDVLGPAGVAHVTAEVTAIDADGRRVTTSTGASYSYDRLVLASGSHVVKPALPGLAEFGFDVDTYDGAVRLQQHLQGLAGGPLTSAAATVVVVGAGLTGIETACELPGRLHALFARGDGVTPRVVLIDHNPFVGSDMGLSARPVIEQALLDNGVETRTGVSVAAVSPGGVTLSSGERLAAATVVWCAGMRASRLTEQLPVARDRLGRLQVDDYLRVIGVPAMFAAGDVAAARMDDEHLSVMSCQHGRPMGRYAGCNVINDLFDQPLLALRIPWYVTVLDLGSAGAVYTEGWERKVVSQGAPAKTTKQSINTRRIYPPLNGSRADLLAAAAPRVQPRP
NADH dehydrogenase-like protein MT1860 (EC 1.6.-.-)
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
83,331
400
41,940
FAD;Flavoprotein;Oxidoreductase;Reference proteome
GO:0003955; GO:0019646
Evidence at transcript level
2
null
null
null
PF07992;
IPR036188;IPR023753;IPR051169;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
MT1860
false
Mycobacterium tuberculosis
684
row_413412
false
null
432,143
P9WPL6
MTSTSIPTFPFDRPVPTEPSPMLSELRNSCPVAPIELPSGHTAWLVTRFDDVKGVLSDKRFSCRAAAHPSSPPFVPFVQLCPSLLSIDGPQHTAARRLLAQGLNPGFIARMRPVVQQIVDNALDDLAAAEPPVDFQEIVSVPIGEQLMAKLLGVEPETVHELAAHVDAAMSVCEIGDEEVSRRWSALCTMVIDILHRKLAEPGDDLLSTIAQANRQQSTMTDEQVVGMLLTVVIGGVDTPIAVITNGLASLLHHRDQYERLVEDPGRVARAVEEIVRFNPATEIEHLRVVTEDVVIAGTALSAGSPAFTSITSANRDSDQFLDPDEFDVERNPNEHIAFGYGPHACPASAYSRMCLTTFFTSLTQRFPQLQLARPFEDLERRGKGLHSVGIKELLVTWPT
Putative cytochrome P450 141 (EC 1.14.-.-)
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
83,331
400
43,732
Cell membrane;Heme;Iron;Membrane;Metal-binding;Monooxygenase;Oxidoreductase;Reference proteome;Transmembrane;Transmembrane helix
GO:0004497; GO:0005506; GO:0005886; GO:0016705; GO:0020037
Inferred from homology
2
SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
null
TRANSMEM 225..245; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 294..314; /note="Helical"; /evidence="ECO:0000255"
PF00067;
IPR001128;IPR002397;IPR017972;IPR036396;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
cyp141 MT3203
false
Mycobacterium tuberculosis
685
row_413888
false
null
26,804
P9WI63
MVEAGTRDPLESALLDSRYLVQAKIASGGTSTVYRGLDVRLDRPVALKVMDSRYAGDEQFLTRFRLEARAVARLNNRALVAVYDQGKDGRHPFLVMELIEGGTLRELLIERGPMPPHAVVAVLRPVLGGLAAAHRAGLVHRDVKPENILISDDGDVKLADFGLVRAVAAASITSTGVILGTAAYLSPEQVRDGNADPRSDVYSVGVLVYELLTGHTPFTGDSALSIAYQRLDADVPRASAVIDGVPPQFDELVACATARNPADRYADAIAMGADLEAIAEELALPEFRVPAPRNSAQHRSAALYRSRITQQGQLGAKPVHHPTRQLTRQPGDCSEPASGSEPEHEPITGQFAGIAIEEFIWARQHARRMVLVWVSVVLAITGLVASAAWTIGSNLSGLL
Serine/threonine-protein kinase PknL (EC 2.7.11.1)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
399
42,834
ATP-binding;Cell membrane;Kinase;Membrane;Nucleotide-binding;Phosphoprotein;Reference proteome;Serine/threonine-protein kinase;Transferase;Transmembrane;Transmembrane helix
GO:0004672; GO:0004674; GO:0005524; GO:0005886; GO:0045717; GO:0106310
Evidence at protein level
5
SUBCELLULAR LOCATION: Cell membrane {ECO:0000305|PubMed:18175374}; Single-pass membrane protein {ECO:0000305|PubMed:18175374}.
null
TRANSMEM 369..389; /note="Helical"; /evidence="ECO:0000255"
PF00069;
IPR011009;IPR000719;IPR008271;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
pknL Rv2176 MTV021.09
false
Mycobacterium tuberculosis
686
row_23450
false
null
26,840
P9WIQ1
MQPMTARFDLFVVGSGFFGLTIAERVATQLDKRVLVLERRPHIGGNAYSEAEPQTGIEVHKYGAHLFHTSNKRVWDYVRQFTDFTDYRHRVFAMHNGQAYQFPMGLGLVSQFFGKYFTPEQARQLIAEQAAEIDTADAQNLEEKAISLIGRPLYEAFVKGYTAKQWQTDPKELPAANITRLPVRYTFDNRYFSDTYEGLPTDGYTAWLQNMAADHRIEVRLNTDWFDVRGQLRPGSPAAPVVYTGPLDRYFDYAEGRLGWRTLDFEVEVLPIGDFQGTAVMNYNDLDVPYTRIHEFRHFHPERDYPTDKTVIMREYSRFAEDDDEPYYPINTEADRALLATYRARAKSETASSKVLFGGRLGTYQYLDMHMAIASALNMYDNVLAPHLRDGVPLLQDGA
UDP-galactopyranose mutase (UGM) (EC 5.4.99.9) (UDP-GALP mutase) (Uridine 5-diphosphate galactopyranose mutase)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
399
45,814
3D-structure;Cell wall biogenesis/degradation;FAD;Flavoprotein;Isomerase;Reference proteome
GO:0005829; GO:0005886; GO:0008767; GO:0009274; GO:0045227; GO:0050660; GO:0071555; GO:0071766
Evidence at protein level
5
null
null
null
PF03275;PF13450;
IPR004379;IPR015899;
1V0J;4RPG;4RPH;4RPJ;4RPK;4RPL;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
glf Rv3809c
false
Mycobacterium tuberculosis
687
row_23485
false
null
546,488
P9WHW6
MPDPGWAARTPEANDLLLKAGTGVGTHLANQTAWTTLGASHHASGVASAINTAATAASWLGVGSAASALNVTMLNATLHGLAGWVDVKPAVVSTAIAAFETANAAMRPAPECMVNRDEWGVDNAINPSVLWTLTPRIVSLDVEYFGVMWPNNAAVGATYGGVLAALAESLAIPPPVATMGASPAAPAQAAAAVGQAAAEAAAGCGMRSAYQGVQAGSTGAGQSTSAGENFGNQLSTFMQPMQAVMQAAPQALQAPSGLMQAPMSAMQPLQSMVGMFANPGALGMGGAAPGASAASAAGGISAAATEVGAGGGGAALGGGGMPATSFTRPVSAFESGTSGRPVGLRPSGALGADVVRAPTTTVGGTPIGGMPVGHAAGGHRGSHGKSEQAATVRVVDDRR
Uncharacterized PPE family protein PPE69
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
83,331
399
38,838
Reference proteome
null
Inferred from homology
1
null
null
null
PF00823;
IPR000030;IPR038332;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
PPE69 MT4007
false
Mycobacterium tuberculosis
688
row_526583
false
null
27,027
P9WPL5
MTEAPDVDLADGNFYASREARAAYRWMRANQPVFRDRNGLAAASTYQAVIDAERQPELFSNAGGIRPDQPALPMMIDMDDPAHLLRRKLVNAGFTRKRVKDKEASIAALCDTLIDAVCERGECDFVRDLAAPLPMAVIGDMLGVRPEQRDMFLRWSDDLVTFLSSHVSQEDFQITMDAFAAYNDFTRATIAARRADPTDDLVSVLVSSEVDGERLSDDELVMETLLILIGGDETTRHTLSGGTEQLLRNRDQWDLLQRDPSLLPGAIEEMLRWTAPVKNMCRVLTADTEFHGTALCAGEKMMLLFESANFDEAVFCEPEKFDVQRNPNSHLAFGFGTHFCLGNQLARLELSLMTERVLRRLPDLRLVADDSVLPLRPANFVSGLESMPVVFTPSPPLG
Steroid C26-monooxygenase (EC 1.14.15.28) (Cholest-4-en-3-one C26-monooxygenase) (Cholest-4-en-3-one C26-monooxygenase [(25R)-3-oxocholest-4-en-26-oate forming]) (Cholesterol C26-monooxygenase) (Cholesterol C26-monooxygenase [(25R)-3beta-hydroxycholest-5-en-26-oate forming]) (Cytochrome P450 142) (Steroid C27-monooxygenase)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
398
44,399
3D-structure;Cholesterol metabolism;Heme;Iron;Lipid degradation;Lipid metabolism;Metal-binding;Monooxygenase;NADP;Oxidoreductase;Reference proteome;Steroid metabolism;Sterol metabolism;Virulence
GO:0005506; GO:0006707; GO:0008395; GO:0009274; GO:0020037; GO:0031073; GO:0036199
Evidence at protein level
5
null
null
null
PF00067;
IPR001128;IPR002397;IPR017972;IPR036396;
2XKR;7P5T;7QJL;7QQ7;8A6W;8A9P;8S53;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
cyp142 cyp142A1 Rv3518c MTV023.25c
false
Mycobacterium tuberculosis
689
row_23666
false
null
112,186
A1KJ75
MSERVILAYSGGLDTSVAISWIGKETGREVVAVAIDLGQGGEHMDVIRQRALDCGAVEAVVVDARDEFAEGYCLPTVLNNALYMDRYPLVSAISRPLIVKHLVAAAREHGGGIVAHGCTGKGNDQVRFEVGFASLAPDLEVLAPVRDYAWTREKAIAFAEENAIPINVTKRSPFSIDQNVWGRAVETGFLEHLWNAPTKDIYAYTEDPTINWGVPDEVIVGFERGVPVSVDGKPVSMLAAIEELNRRAGAQGVGRLDVVEDRLVGIKSREIYEAPGAMVLITAHTELEHVTLERELGRFKRQTDQRWAELVYDGLWYSPLKAALEAFVAKTQEHVSGEVRLVLHGGHIAVNGRRSAESLYDFNLATYDEGDSFDQSAARGFVYVHGLSSKLAARRDLR
Argininosuccinate synthase (EC 6.3.4.5) (Citrulline--aspartate ligase)
Mycobacterium bovis (strain BCG / Pasteur 1173P2)
410,289
398
43,682
Amino-acid biosynthesis;Arginine biosynthesis;ATP-binding;Cytoplasm;Ligase;Nucleotide-binding
GO:0000050; GO:0000053; GO:0004055; GO:0005524; GO:0005737; GO:0006526
Inferred from homology
3
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00005}.
null
null
PF20979;PF00764;
IPR048268;IPR048267;IPR001518;IPR018223;IPR023434;IPR024074;IPR014729;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype), Mycobacterium tuberculosis variant bovis BCG (no rank)
argG BCG_1697
false
Mycobacterium tuberculosis
690
row_100651
false
null
213,190
P9WQ67
MAYDVARVRGLHPSLGDGWVHFDAPAGMLIPDSVATTVSTAFRRSGASTVGAHPSARRSAAVLDAAREAVADLVNADPGGVVLGADRAVLLSLLAEASSSRAGLGYEVIVSRLDDEANIAPWLRAAHRYGAKVKWAEVDIETGELPTWQWESLISKSTRLVAVNSASGTLGGVTDLRAMTKLVHDVGALVVVDHSAAAPYRLLDIRETDADVVTVNAHAWGGPPIGAMVFRDPSVMNSFGSVSTNPYATGPARLEIGVHQFGLLAGVVASIEYLAALDESARGSRRERLAVSMQSADAYLNRVFDYLMVSLRSLPLVMLIGRPEAQIPVVSFAVHKVPADRVVQRLADNGILAIANTGSRVLDVLGVNDVGGAVTVGLAHYSTMAEVDQLVRALASLG
Uncharacterized protein Rv3778c
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
398
41,852
3D-structure;Reference proteome
GO:0005886; GO:0009274
Evidence at protein level
3
null
null
null
PF00266;
IPR000192;IPR011340;IPR015424;IPR015421;IPR015422;
3CAI;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
Rv3778c
false
Mycobacterium tuberculosis
691
row_199388
false
null
403,123
O07717
MTYGEAVADVLEFGQSEGEPIGMAPEEWRAFAARASLHAARAKAKELGADPPWDCELAKTPEGYYQIRGGIPYAIAKSLAAAPFADILWMETKTADLADARQFAEAIHAEFPDQMLAYNLSPSFNWDTTGMTDEEMRRFPEELGKMGFVFNFITYGGHQIDGVAAEEFATALRQDGMLALARLQRKMRLVESPYRTPQTLVGGPRSDAALAASSGRTATTKAMGKGSTQHQHLVQTEVPRKLLEEWLAMWSGHYQLKDKLRVQLRPQRAGSEVLELGIHGESDDKLANVIFQPIQDRRGRTILLVRDQNTFGAELRQKRLMTLIHLWLVHRFKAQAVHYVTPTDDNLYQTSKMKSHGIFTEVNQEVGEIIVAEVNHPRIAELLTPDRVALRKLITKEA
Putative isocitrate lyase subunit B (ICL) (EC 4.1.3.1) (Isocitrase) (Isocitratase)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
398
44,582
3D-structure;Lyase;Reference proteome
GO:0004451; GO:0019752
Evidence at protein level
2
null
null
null
PF00463;
IPR006254;IPR015813;IPR040442;
8G8K;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
aceAb Rv1916 RVBD_1916 P425_01981
false
Mycobacterium tuberculosis
692
row_385655
false
null
432,133
P9WPI5
MRTPVILVAGQDHTDEVTGALLRRTGTVVVEHRFDGHVVRRMTATLSRGELITTEDALEFAHGCVSCTIRDDLLVLLRRLHRRDNVGRIVVHLAPWLEPQPICWAIDHVRVCVGHGYPDGPAALDVRVAAVVTCVDCVRWLPQSLGEDELPDGRTVAQVTVGQAEFADLLVLTHPEPVAVAVLRRLAPRARITGGVDRVELALAHLDDNSRRGRTDTPHTPLLAGLPPLAADGEVAIVEFSARRPFHPQRLHAAVDLLLDGVVRTRGRLWLANRPDQVMWLESAGGGLRVASAGKWLAAMAASEVAYVDLERRLFADLMWVYPFGDRHTAMTVLVCGADPTDIVNALNAALLSDDEMASPQRWQSYVDPFGDWHDDPCHEMPDAAGEFSAHRNSGESR
Zinc chaperone Rv0106 (EC 3.6.5.-)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
398
43,700
Chaperone;GTP-binding;Hydrolase;Nucleotide-binding;Reference proteome
GO:0005525; GO:0016787
Evidence at protein level
2
null
null
null
PF02492;PF07683;
IPR011629;IPR003495;IPR027417;IPR051927;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
Rv0106 MTCY251.25
false
Mycobacterium tuberculosis
693
row_413878
false
null
26,794
P9WHR9
MTPSQWLDIAVLAVAFIAAISGWRAGALGSMLSFGGVLLGATAGVLLAPHIVSQISAPRAKLFAALFLILALVVVGEVAGVVLGRAVRGAIRNRPIRLIDSVIGVGVQLVVVLTAAWLLAMPLTQSKEQPELAAAVKGSRVLARVNEAAPTWLKTVPKRLSALLNTSGLPAVLEPFSRTPVIPVASPDPALVNNPVVAATEPSVVKIRSLAPRCQKVLEGTGFVISPDRVMTNAHVVAGSNNVTVYAGDKPFEATVVSYDPSVDVAILAVPHLPPPPLVFAAEPAKTGADVVVLGYPGGGNFTATPARIREAIRLSGPDIYGDPEPVTRDVYTIRADVEQGDSGGPLIDLNGQVLGVVFGAAIDDAETGFVLTAGEVAGQLAKIGATQPVGTGACVS
Serine protease Rv3671c (EC 3.4.21.-)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
397
40,721
3D-structure;Autocatalytic cleavage;Disulfide bond;Hydrolase;Membrane;Protease;Reference proteome;Transmembrane;Transmembrane helix
GO:0004252; GO:0005576; GO:0005886; GO:0006508; GO:0009274; GO:0009403; GO:0010447; GO:0042783
Evidence at protein level
5
SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
null
TRANSMEM 9..29; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 32..52; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 62..82; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 102..122; /note="Helical"; /evidence="ECO:0000255"
PF02674;PF13365;
IPR003825;IPR047680;IPR009003;IPR043504;IPR001940;
3K6Y;3K6Z;3LT3;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
Rv3671c
false
Mycobacterium tuberculosis
694
row_23440
false
null
26,943
P9WMU9
MTDHVREADDANIDDLLGDLGGTARAERAKLVEWLLEQGITPDEIRATNPPLLLATRHLVGDDGTYVSAREISENYGVDLELLQRVQRAVGLARVDDPDAVVHMRADGEAAARAQRFVELGLNPDQVVLVVRVLAEGLSHAAEAMRYTALEAIMRPGATELDIAKGSQALVSQIVPLLGPMIQDMLFMQLRHMMETEAVNAGERAAGKPLPGARQVTVAFADLVGFTQLGEVVSAEELGHLAGRLAGLARDLTAPPVWFIKTIGDAVMLVCPDPAPLLDTVLKLVEVVDTDNNFPRLRAGVASGMAVSRAGDWFGSPVNVASRVTGVARPGAVLVADSVREALGDAPEADGFQWSFAGPRRLRGIRGDVRLFRVRRGATRTGSGGAAQDDDLAGSSP
pH-sensitive adenylate cyclase Rv1264 (EC 4.6.1.1) (ATP pyrophosphate-lyase) (Adenylyl cyclase)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
397
42,232
3D-structure;Acetylation;ATP-binding;cAMP biosynthesis;Lipid-binding;Lyase;Magnesium;Manganese;Metal-binding;Nucleotide-binding;Reference proteome
GO:0004016; GO:0005524; GO:0006171; GO:0008289; GO:0009268; GO:0010855; GO:0030145; GO:0035556; GO:0042803
Evidence at protein level
5
null
null
null
PF16701;PF00211;
IPR001054;IPR032026;IPR050697;IPR029787;
1Y10;1Y11;2EV1;2EV2;2EV3;2EV4;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
Rv1264 MTCY50.18c
false
Mycobacterium tuberculosis
695
row_23583
false
null
81,934
P9WPZ5
MTVSRLRPYATTVFAEMSALATRIGAVNLGQGFPDEDGPPKMLQAAQDAIAGGVNQYPPGPGSAPLRRAIAAQRRRHFGVDYDPETEVLVTVGATEAIAAAVLGLVEPGSEVLLIEPFYDSYSPVVAMAGAHRVTVPLVPDGRGFALDADALRRAVTPRTRALIINSPHNPTGAVLSATELAAIAEIAVAANLVVITDEVYEHLVFDHARHLPLAGFDGMAERTITISSAAKMFNCTGWKIGWACGPAELIAGVRAAKQYLSYVGGAPFQPAVALALDTEDAWVAALRNSLRARRDRLAAGLTEIGFAVHDSYGTYFLCADPRPLGYDDSTEFCAALPEKVGVAAIPMSAFCDPAAGQASQQADVWNHLVRFTFCKRDDTLDEAIRRLSVLAERPAT
Probable N-succinyldiaminopimelate aminotransferase DapC (DAP-AT) (EC 2.6.1.17)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
397
42,209
3D-structure;Amino-acid biosynthesis;Aminotransferase;Cytoplasm;Lysine biosynthesis;Pyridoxal phosphate;Reference proteome;Transferase
GO:0005737; GO:0009016; GO:0009089; GO:0009274; GO:0016212; GO:0030170
Evidence at protein level
4
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
null
null
PF00155;
IPR004839;IPR051326;IPR015424;IPR015421;IPR015422;
2O0R;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
dapC Rv0858c
false
Mycobacterium tuberculosis
696
row_72372
false
null
539,516
P0A615
MGASGLVWTLTIVLIAGLMLVDYVLHVRKTHVPTLRQAVIQSATFVGIAILFGIAVVVFGGSELAVEYFACYLTDEALSVDNLFVFLVIISSFGVPRLAQQKVLLFGIAFALVTRTGFIFVGAALIENFNSAFYLFGLVLLVMAGNLARPTGLESRDAETLKRSVIIRLADRFLRTSQDYNGDRLFTVSNNKRMMTPLLLVMIAVGGTDILFAFDSIPALFGLTQNVYLVFAATAFSLLGLRQLYFLIDGLLDRLVYLSYGLAVILGFIGVKLMLEALHDNKIPFINGGKPVPTVEVSTTQSLTVIIIVLLITTAASFWSARGRAQNAMARARRYATAYLDLHYETESAERDKIFTALLAAERQINTLPTKYRMQPGQDDDLMTLLCRAHAARDAHM
Uncharacterized membrane protein Mb2742
Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
233,413
397
43,679
Cell membrane;Membrane;Reference proteome;Transmembrane;Transmembrane helix
GO:0005886
Inferred from homology
1
SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
null
TRANSMEM 1..21; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 39..59; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 76..96; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 103..123; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 124..144; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 194..214; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 219..239; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 255..275; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 301..321; /note="Helical"; /evidence="ECO:0000255"
PF03741;
IPR005496;IPR022369;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype)
BQ2027_MB2742
false
Mycobacterium tuberculosis
697
row_519805
false
null
544,325
P59973
MTAPGLTAAVEGIAHNKGELFASFDVDAFEVPHGRDEIWRFTPLRRLRGLHDGSARATGSATITVSERPGVYTQTVRRGDPRLGEGGVPTDRVAAQAFSSFNSATLVTVERDTQVVEPVGITVTGPGEGAVAYGHLQVRIEELGEAVVVIDHRGGGTYADNVEFVVDDAARLTAVWIADWADDTVHLSAHHARIGKDAVLRHVTVMLGGDVVRMSAGVRFCGAGGDAELLGLYFADDGQHLESRLLVDHAHPDCKSNVLYKGALQGDPASSLPDAHTVWVGDVLIRAQATGTDTFEVNRNLVLTDGARADSVPNLEIETGEIVGAGHASATGRFDDEQLFYLRSRGIPEAQARRLVVRGFFGEIIAKIAVPEVRERLTAAIEHELEITESTEKTTVS
Iron-sulfur cluster assembly SufBD family protein Mb1497
Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
233,413
397
42,524
Reference proteome
GO:0016226
Inferred from homology
1
null
null
null
PF01458;
IPR055346;IPR000825;IPR037284;IPR011542;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype)
BQ2027_MB1497
false
Mycobacterium tuberculosis
698
row_524568
false
null
546,607
P9WJU8
MQGISVTGLVKRGWMVRSVFDTIDGIDQLGEQLASVTVTLDKLAAIQPQLVALLPDEIASQQINRELALANYATMSGIYAQTAALIENAAAMGQAFDAAKNDDSFYLPPEAFDNPDFQRGLKLFLSADGKAARMIISHEGDPATPEGISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAATFKDIQDGATYDLLIAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQHLLGIQLYWIVLALAVILLLAVGSDYNLLLISRFKEEIGAGLNTGIIRAMAGTGGVVTAAGLVFAATMSSFVFSDLRVLGQIGTTIGLGLLFDTLVVRAFMTPSIAVLLGRWFWWPQRVRPRPASRMLRPYGPRPVVRELLLREGNDDPRTQVATHR
Probable transport protein MmpL6
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
83,331
397
42,422
Cell membrane;Membrane;Reference proteome;Transmembrane;Transmembrane helix;Transport
GO:0005886
Inferred from homology
1
SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000255}.
null
TRANSMEM 190..210; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 214..234; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 242..262; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 293..313; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 328..348; /note="Helical"; /evidence="ECO:0000255"
PF03176;
IPR004869;IPR050545;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
mmpL6 MT1608
false
Mycobacterium tuberculosis
699
row_526699
false
null
27,030
P9WPP7
MTATVLLEVPFSARGDRIPDAVAELRTREPIRKVRTITGAEAWLVSSYALCTQVLEDRRFSMKETAAAGAPRLNALTVPPEVVNNMGNIADAGLRKAVMKAITPKAPGLEQFLRDTANSLLDNLITEGAPADLRNDFADPLATALHCKVLGIPQEDGPKLFRSLSIAFMSSADPIPAAKINWDRDIEYMAGILENPNITTGLMGELSRLRKDPAYSHVSDELFATIGVTFFGAGVISTGSFLTTALISLIQRPQLRNLLHEKPELIPAGVEELLRINLSFADGLPRLATADIQVGDVLVRKGELVLVLLEGANFDPEHFPNPGSIELDRPNPTSHLAFGRGQHFCPGSALGRRHAQIGIEALLKKMPGVDLAVPIDQLVWRTRFQRRIPERLPVLW
Mycocyclosin synthase (EC 1.14.19.70) (Cytochrome P450 121) (Cytochrome P450 MT2)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
396
43,256
3D-structure;Cytoplasm;Heme;Iron;Metal-binding;Monooxygenase;Oxidoreductase;Reference proteome
GO:0004497; GO:0005506; GO:0005737; GO:0009975; GO:0016491; GO:0016717; GO:0020037; GO:0070025
Evidence at protein level
5
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
null
null
PF00067;
IPR001128;IPR002397;IPR017972;IPR036396;
1N40;1N4G;2IJ5;2IJ7;3CXV;3CXX;3CXY;3CXZ;3CY0;3CY1;3G5F;3G5H;4G1X;4G2G;4G44;4G45;4G46;4G47;4G48;4ICT;4IPS;4IPW;4IQ7;4IQ9;5IBD;5IBE;5IBF;5IBG;5IBH;5IBI;5IBJ;5O4K;5O4L;5OP9;5OPA;5WP2;6GEO;6GEQ;6RQ0;6RQ1;6RQ3;6RQ5;6RQ6;6RQ8;6RQ9;6RQB;6RQD;6RQE;6TE7;6TET;6TEV;6UPG;6UPI;7NQM;7NQN;7NQO;8TDP;8TDQ;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
cyp121 Rv2276 MTCY339.34c
false
Mycobacterium tuberculosis
700
row_23669
false
null
81,878
P9WNN1
MAKAKFQRTKPHVNIGTIGHVDHGKTTLTAAITKVLHDKFPDLNETKAFDQIDNAPEERQRGITINIAHVEYQTDKRHYAHVDAPGHADYIKNMITGAAQMDGAILVVAATDGPMPQTREHVLLARQVGVPYILVALNKADAVDDEELLELVEMEVRELLAAQEFDEDAPVVRVSALKALEGDAKWVASVEELMNAVDESIPDPVRETDKPFLMPVEDVFTITGRGTVVTGRVERGVINVNEEVEIVGIRPSTTKTTVTGVEMFRKLLDQGQAGDNVGLLLRGVKREDVERGQVVTKPGTTTPHTEFEGQVYILSKDEGGRHTPFFNNYRPQFYFRTTDVTGVVTLPEGTEMVMPGDNTNISVKLIQPVAMDEGLRFAIREGGRTVGAGRVTKIIK
Elongation factor Tu (EF-Tu) (EC 3.6.5.3)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
396
43,594
3D-structure;Cytoplasm;Elongation factor;GTP-binding;Hydrolase;Magnesium;Metal-binding;Nucleotide-binding;Protein biosynthesis;Reference proteome
GO:0001666; GO:0003746; GO:0003924; GO:0005525; GO:0005576; GO:0005829; GO:0005886; GO:0006414; GO:0009274; GO:0010039; GO:0035375
Evidence at protein level
4
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00118}.
null
null
PF00009;PF03144;PF03143;
IPR041709;IPR050055;IPR004161;IPR033720;IPR031157;IPR027417;IPR005225;IPR000795;IPR009000;IPR009001;IPR004541;IPR004160;
7VMX;7VOK;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
tuf Rv0685 MTCY210.02
false
Mycobacterium tuberculosis
701
row_72319
false
null
212,720
P9WJP0
MQTRAPWSLPEATLAYFPNARFVSSDRDLGAGAAPGIAASRSTACQTWGGITVADPGSGPTGFGHVPVLAQRCFELLTPALTRYYPDGSQAVLLDATIGAGGHAERFLEGLPGLRLIGLDRDPTALDVARSRLVRFADRLTLVHTRYDCLGAALAESGYAAVGSVDGILFDLGVSSMQLDRAERGFAYATDAPLDMRMDPTTPLTAADIVNTYDEAALADILRRYGEERFARRIAAGIVRRRAKTPFTSTAELVALLYQAIPAPARRVGGHPAKRTFQALRIAVNDELESLRTAVPAALDALAIGGRIAVLAYQSLEDRIVKRVFAEAVASATPAGLPVELPGHEPRFRSLTHGAERASVAEIERNPRSTPVRLRALQRVEHRAQSQQWATEKGDS
Ribosomal RNA small subunit methyltransferase H (EC 2.1.1.199) (16S rRNA m(4)C1402 methyltransferase) (rRNA (cytosine-N(4)-)-methyltransferase RsmH)
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
83,331
396
42,529
Cytoplasm;Methyltransferase;Reference proteome;rRNA processing;S-adenosyl-L-methionine;Transferase
GO:0005737; GO:0070475; GO:0071424
Inferred from homology
3
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01007}.
null
null
PF01795;
IPR002903;IPR023397;IPR029063;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
rsmH mraW MT2223
false
Mycobacterium tuberculosis
702
row_198926
false
null
212,978
P9WND6
MAEAWFETVAIAQQRAKRRLPKSVYSSLIAASEKGITVADNVAAFSELGFAPHVIGATDKRDLSTTVMGQEVSLPVIISPTGVQAVDPGGEVAVARAAAARGTVMGLSSFASKPIEEVIAANPKTFFQVYWQGGRDALAERVERARQAGAVGLVVTTDWTFSHGRDWGSPKIPEEMNLKTILRLSPEAITRPRWLWKFAKTLRPPDLRVPNQGRRGEPGPPFFAAYGEWMATPPPTWEDIGWLRELWGGPFMLKGVMRVDDAKRAVDAGVSAISVSNHGGNNLDGTPASIRALPAVSAAVGDQVEVLLDGGIRRGSDVVKAVALGARAVMIGRAYLWGLAANGQAGVENVLDILRGGIDSALMGLGHASVHDLSPADILVPTGFIRDLGVPSRRDV
Pre-mycofactocin synthase (PMFT synthase) (EC 1.4.3.26)
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
83,331
396
42,161
Flavoprotein;FMN;Oxidoreductase;Reference proteome
GO:0010181; GO:0016491; GO:0140604
Inferred from homology
3
null
null
null
PF01070;
IPR013785;IPR012133;IPR000262;IPR037396;IPR023989;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
mftD lldD1 MT0721
false
Mycobacterium tuberculosis
703
row_199179
false
null
546,517
P9WI24
MVDFGALPPEINSARMYAGPGSASLVAAAKMWDSVASDLFSAASAFQSVVWGLTTGSWIGSSAGLMVAAASPYVAWMSVTAGQAELTAAQVRVAAAAYETAYGLTVPPPVIAENRAELMILIATNLLGQNTPAIAVNEAEYGEMWAQDAAAMFGYAAATATATEALLPFEDAPLITNPGGLLEQAVAVEEAIDTAAANQLMNNVPQALQQLAQPTKSIWPFDQLSELWKAISPHLSPLSNIVSMLNNHVSMTNSGVSMASTLHSMLKGFAPAAAQAVETAAQNGVQAMSSLGSQLGSSLGSSGLGAGVAANLGRAASVGSLSVPQAWAAANQAVTPAARALPLTSLTSAAQTAPGHMLGGLPLGQLTNSGGGFGGVSNALRMPPRAYVMPRVPAAG
Uncharacterized PPE family protein PPE19
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
83,331
396
40,016
Reference proteome
GO:0052572
Inferred from homology
1
null
null
null
PF00823;PF12484;
IPR022171;IPR000030;IPR038332;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
PPE19 MT1406
false
Mycobacterium tuberculosis
704
row_526610
false
null
81,792
P9WJY7
MRGQAANLVLATWISVVNFWAWNLIGPLSTSYARDMSLSSAEASLLVATPILVGALGRIVTGPLTDRFGGRAMLIAVTLASILPVLAVGVAATMGSYALLVFFGLFLGVAGTIFAVGIPFANNWYQPARRGFSTGVFGMGMVGTALSAFFTPRFVRWFGLFTTHAIVAAALASTAVVAMVVLRDAPYFRPNADPVLPRLKAAARLPVTWEMSFLYAIVFGGFVAFSNYLPTYITTIYGFSTVDAGARTAGFALAAVLARPVGGWLSDRIAPRHVVLASLAGTALLAFAAALQPPPEVWSAATFITLAVCLGVGTGGVFAWVARRAPAASVGSVTGIVAAAGGLGGYFPPLVMGATYDPVDNDYTVGLLLLVATALVACTYTALHAREPVSEEASR
Probable nitrate/nitrite transporter NarK2
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
395
41,109
Cell membrane;Membrane;Nitrate assimilation;Reference proteome;Transmembrane;Transmembrane helix;Transport
GO:0001666; GO:0005886; GO:0015112; GO:0042128; GO:0090352
Evidence at protein level
4
SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
null
TRANSMEM 8..28; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 45..65; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 72..92; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 98..118; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 131..151; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 157..177; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 205..225; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 244..266; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 274..294; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 301..321; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 333..353; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 365..385; /note="Helical"; /evidence="ECO:0000255"
PF07690;
IPR011701;IPR020846;IPR036259;IPR044772;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
narK2 narK-3 Rv1737c
false
Mycobacterium tuberculosis
705
row_72238
false
null
81,890
P9WNV9
MAQREWVEKDFYQELGVSSDASPEEIKRAYRKLARDLHPDANPGNPAAGERFKAVSEAHNVLSDPAKRKEYDETRRLFAGGGFGGRRFDSGFGGGFGGFGVGGDGAEFNLNDLFDAASRTGGTTIGDLFGGLFGRGGSARPSRPRRGNDLETETELDFVEAAKGVAMPLRLTSPAPCTNCHGSGARPGTSPKVCPTCNGSGVINRNQGAFGFSEPCTDCRGSGSIIEHPCEECKGTGVTTRTRTINVRIPPGVEDGQRIRLAGQGEAGLRGAPSGDLYVTVHVRPDKIFGRDGDDLTVTVPVSFTELALGSTLSVPTLDGTVGVRVPKGTADGRILRVRGRGVPKRSGGSGDLLVTVKVAVPPNLAGAAQEALEAYAAAERSSGFNPRAGWAGNR
Chaperone protein DnaJ 1
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
395
41,345
Chaperone;Cytoplasm;DNA replication;Metal-binding;Reference proteome;Repeat;Stress response;Zinc;Zinc-finger
GO:0005524; GO:0005737; GO:0005886; GO:0006260; GO:0008270; GO:0009274; GO:0009408; GO:0010468; GO:0031072; GO:0042026; GO:0051082; GO:0051085; GO:0061077
Evidence at protein level
4
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01152}.
null
null
PF00226;PF01556;PF00684;
IPR012724;IPR002939;IPR001623;IPR018253;IPR008971;IPR001305;IPR036410;IPR036869;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
dnaJ1 Rv0352 MTCY13E10.12
false
Mycobacterium tuberculosis
706
row_72330
false
null
276,853
Q7D515
MQDEAMRRSGANSPAGDSLADRWRAARPPVAGLHLDSAACSRQSFAALDAAAQHARHEAEVGGYVAAEAAAAVLDAGRAAVAALSGLPDAEVVFTTGSLHALDLLLGSWPGENRTLACLPGEYGPNLAVMAAHGFDVRPLPTLQDGRVALDDAAFMLADDPPDLVHLTVVASHRGVAQPLAMVAQLCTELKLPLVVDAAQGLGHVDCAVGADVTYASSRKWIAGPRGVGVLAVRPELMERLRARLPAPDWMPPLTVAQQLGFGEANVAARVGFSVALGEHLACGPQAIRARLAELGDIARTVLADVSGWRVVEAVDEPSAITTLAPIDGADPAAVRAWLLSQRRIVTTYAGVERAPLELPAPVLRISPHVDNTADDLDAFAEALVAATAATSGER
Probable hercynylcysteine sulfoxide lyase (EC 4.4.-.-)
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
83,331
395
41,021
Lyase;Pyridoxal phosphate;Reference proteome
GO:1990411
Evidence at transcript level
3
null
null
null
PF00266;
IPR000192;IPR027563;IPR015424;IPR015421;IPR015422;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
egtE MT3803
false
Mycobacterium tuberculosis
707
row_261242
false
null
26,855
P9WJA1
MTSIQQRDAQSVLAAIDNLLPEIRDRAQATEDLRRLPDETVKALDDVGFFTLLQPQQWGGLQCDPALFFEATRRLASVCGSTGWVSSIVGVHNWHLALFDQRAQEEVWGEDPSTRISSSYAPMGAGVVVDGGYLVNGSWNWSSGCDHASWTFVGGPVIKDGRPVDFGSFLIPRSEYEIKDVWYVVGLRGTGSNTLVVKDVFVPRHRFLSYKAMNDHTAGGLATNSAPVYKMPWGTMHPTTISAPIVGMAYGAYAAHVEHQGKRVRAAFAGEKAKDDPFAKVRIAEAASDIDAAWRQLIGNVSDEYALLAAGKEIPFELRARARRDQVRATGRSIASIDRLFEASGATALSNEAPIQRFWRDAHAGRVHAANDPERAYVIFGNHEFGLPPGDTMV
Flavin-dependent monooxygenase, oxygenase subunit HsaA (EC 1.14.14.12) (3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione 4-hydroxylase, oxygenase subunit) (3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione monooxygenase)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
394
43,143
3D-structure;Aromatic hydrocarbons catabolism;FAD;Flavoprotein;FMN;Lipid degradation;Lipid metabolism;Monooxygenase;Oxidoreductase;Reference proteome;Steroid metabolism
GO:0003995; GO:0005737; GO:0005886; GO:0006694; GO:0006707; GO:0016712; GO:0033539; GO:0036383; GO:0050660; GO:0051701
Evidence at protein level
5
null
null
null
PF08028;PF02771;
IPR050741;IPR013107;IPR046373;IPR036250;IPR013786;IPR037069;IPR009100;IPR054617;
3AFE;3AFF;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
hsaA Rv3570c
false
Mycobacterium tuberculosis
708
row_23498
false
null
212,004
P96877
MPTSNPAKPLDGFRVLDFTQNVAGPLAGQVLVDLGAEVIKVEAPGGEAARQITSVLPGRPPLATYFLPNNRGKKSVTVDLTTEQAKQQMLRLADTADVVLEAFRPGTMEKLGLGPDDLRSRNPNLIYARLTAYGGNGPHGSRPGIDLVVAAEAGMTTGMPTPEGKPQIIPFQLVDNASGHVLAQAVLAALLHRERNGVADVVQVAMYDVAVGLQANQLMMHLNRAASDQPKPEPAPKAKRRKGVGFATQPSDAFRTADGYIVISAYVPKHWQKLCYLIGRPDLVEDQRFAEQRSRSINYAELTAELELALASKTATEWVQLLQANGLMACLAHTWKQVVDTPLFAENDLTLEVGRGADTITVIRTPARYASFRAVVTDPPPTAGEHNAVFLARP
Probable fatty acyl-CoA transferase Rv3272 (EC 2.8.3.-)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
394
42,459
3D-structure;Reference proteome;Transferase
GO:0016740
Evidence at protein level
3
null
null
null
PF02515;
IPR050483;IPR003673;IPR044855;IPR023606;
5YIT;5YIY;5YX6;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
Rv3272
false
Mycobacterium tuberculosis
709
row_198238
false
null
546,513
P9WI16
MTLDVPVNQGHVPPGSVACCLVGVTAVADGIAGHSLSNFGALPPEINSGRMYSGPGSGPLMAAAAAWDGLAAELSSAATGYGAAISELTNMRWWSGPASDSMVAAVLPFVGWLSTTATLAEQAAMQARAAAAAFEAAFAMTVPPPAIAANRTLLMTLVDTNWFGQNTPAIATTESQYAEMWAQDAAAMYGYASAAAPATVLTPFAPPPQTTNATGLVGHATAVAALRGQHSWAAAIPWSDIQKYWMMFLGALATAEGFIYDSGGLTLNALQFVGGMLWSTALAEAGAAEAAAGAGGAAGWSAWSQLGAGPVAASATLAAKIGPMSVPPGWSAPPATPQAQTVARSIPGIRSAAEAAETSVLLRGAPTPGRSRAAHMGRRYGRRLTVMADRPNVG
Uncharacterized PPE family protein PPE23
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
83,331
394
39,778
Reference proteome
GO:0052572
Inferred from homology
1
null
null
null
PF00823;PF12484;
IPR022171;IPR000030;IPR038332;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
PPE23 MT1746
false
Mycobacterium tuberculosis
710
row_526606
false
null
4,041
H8F0D7
MTGPLAAARSVAATKSMTAPTVDERPDIKKGLAGVVVDTTAISKVVPQTNSLTYRGYPVQDLAARCSFEQVAFLLWRGELPTDAELALFSQRERASRRVDRSMLSLLAKLPDNCHPMDVVRTAISYLGAEDPDEDDAAANRAKAMRMMAVLPTIVAIDMRRRRGLPPIAPHSGLGYAQNFLHMCFGEVPETAVVSAFEQSMILYAEHGFNASTFAARVVTSTQSDIYSAVTGAIGALKGRLHGGANEAVMHDMIEIGDPANAREWLRAKLARKEKIMGFGHRVYRHGDSRVPTMKRALERVGTVRDGQRWLDIYQVLAAEMASATGILPNLDFPTGPAYYLMGFDIASFTPIFVMSRITGWTAHIMEQATANALIRPLSAYCGHEQRVLPGTF
2-methylcitrate synthase (2-MCS) (MCS) (EC 2.3.3.5) (Citrate synthase) (CS) (EC 2.3.3.16)
Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)
652,616
393
42,969
Transferase;Tricarboxylic acid cycle
GO:0004108; GO:0005829; GO:0005975; GO:0006099; GO:0019679; GO:0036440; GO:0050440
Evidence at protein level
5
null
null
null
PF00285;
IPR011278;IPR016142;IPR016143;IPR002020;IPR019810;IPR024176;IPR036969;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
gltA1 ERDMAN_1267 Q643_01184
false
Mycobacterium tuberculosis
711
row_3197
false
null
27,019
P9WPF1
MNVSAESGAPRRAGQRHEVGLAQLPPAPPTTVAVIEGLATGTPRRVVNQSDAADRVAELFLDPGQRERIPRVYQKSRITTRRMAVDPLDAKFDVFRREPATIRDRMHLFYEHAVPLAVDVSKRALAGLPYRAAEIGLLVLATSTGFIAPGVDVAIVKELGLSPSISRVVVNFMGCAAAMNALGTATNYVRAHPAMKALVVCIELCSVNAVFADDINDVVIHSLFGDGCAALVIGASQVQEKLEPGKVVVRSSFSQLLDNTEDGIVLGVNHNGITCELSENLPGYIFSGVAPVVTEMLWDNGLQISDIDLWAIHPGGPKIIEQSVRSLGISAELAAQSWDVLARFGNMLSVSLIFVLETMVQQAESAKAISTGVAFAFGPGVTVEGMLFDIIRR
Alpha-pyrone synthesis polyketide synthase-like Pks18 (EC 2.3.1.-) (Alpha-pyrone synthesis polyketide synthase type III Pks18) (Chalcone synthase-like protein) (CHS-like)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
393
42,032
3D-structure;Acyltransferase;Fatty acid metabolism;Lipid metabolism;Reference proteome;Transferase
GO:0006633; GO:0009715; GO:0016747; GO:0030639
Evidence at protein level
5
null
null
null
PF02797;PF00195;
IPR012328;IPR001099;IPR011141;IPR016039;
1TED;1TEE;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
pks18 Rv1372
false
Mycobacterium tuberculosis
712
row_23658
false
null
27,079
P9WQI3
MAEIVLDHVNKSYPDGHTAVRDLNLTIADGEFLILVGPSGCGKTTTLNMIAGLEDISSGELRIAGERVNEKAPKDRDIAMVFQSYALYPHMTVRQNIAFPLTLAKMRKADIAQKVSETAKILDLTNLLDRKPSQLSGGQRQRVAMGRAIVRHPKAFLMDEPLSNLDAKLRVQMRGEIAQLQRRLGTTTVYVTHDQTEAMTLGDRVVVMYGGIAQQIGTPEELYERPANLFVAGFIGSPAMNFFPARLTAIGLTLPFGEVTLAPEVQGVIAAHPKPENVIVGVRPEHIQDAALIDAYQRIRALTFQVKVNLVESLGADKYLYFTTESPAVHSVQLDELAEVEGESALHENQFVARVPAESKVAIGQSVELAFDTARLAVFDADSGANLTIPHRA
Trehalose import ATP-binding protein SugC (EC 7.5.2.-) (MtbSugC) (Nucleotide-binding domain of SugABC transporter) (NBD of SugABC transporter) (SugABC transporter ATPase SugC)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
393
42,915
3D-structure;ATP-binding;Cell inner membrane;Cell membrane;Membrane;Nucleotide-binding;Reference proteome;Sugar transport;Translocase;Transport
GO:0005524; GO:0005886; GO:0015574; GO:0015771; GO:0016887; GO:0035796; GO:0042802; GO:0042803; GO:0043211; GO:0051701; GO:0055052
Evidence at protein level
5
SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Peripheral membrane protein {ECO:0000305}; Cytoplasmic side {ECO:0000305}.
null
null
PF00005;PF17912;
IPR003593;IPR003439;IPR017871;IPR015855;IPR047641;IPR008995;IPR012340;IPR040582;IPR027417;
8JA7;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
sugC Rv1238
false
Mycobacterium tuberculosis
713
row_23712
false
null
67,936
O06159
MSGEDSIRSFPVPDLGEGLQEVTVTCWSVAVGDDVEINQTLCSVETAKAEVEIPSPYAGRIVELGGAEGDVLKVGAELVRIDTGPTAVAQPNGEGAVPTLVGYGADTAIETSRRTSRPLAAPVVRKLAKELAVDLAALQRGSGAGGVITRADVLAAARGGVGAGPDVRPVHGVHARMAEKMTLSHKEIPTAKASVEVICAELLRLRDRFVSAAPEITPFALTLRLLVIALKHNVILNSTWVDSGEGPQVHVHRGVHLGFGAATERGLLVPVVTDAQDKNTRELASRVAELITGAREGTLTPAELRGSTFTVSNFGALGVDDGVPVINHPEAAILGLGAIKPRPVVVGGEVVARPTMTLTCVFDHRVVDGAQVAQFMCELRDLIESPETALLDL
Dihydrolipoyllysine-residue acyltransferase component of branched-chain alpha-ketoacid dehydrogenase complex (EC 2.3.1.168) (Branched-chain alpha-ketoacid dehydrogenase complex component E2) (BCKADH E2) (Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
393
41,061
3D-structure;Acyltransferase;Lipoyl;Reference proteome;Transferase
GO:0005737; GO:0005886; GO:0009274; GO:0016407; GO:0031405; GO:0043754
Evidence at protein level
4
null
null
null
PF00198;PF00364;PF02817;
IPR001078;IPR050743;IPR000089;IPR023213;IPR036625;IPR004167;IPR011053;
3L60;6ZZN;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
bkdC pdhC Rv2495c
false
Mycobacterium tuberculosis
714
row_59028
false
null
81,944
P9WQ71
MAYLDHAATTPMHPAAIEAMAAVQRTIGNASSLHTSGRSARRRIEEARELIADKLGARPSEVIFTAGGTESDNLAVKGIYWARRDAEPHRRRIVTTEVEHHAVLDSVNWLVEHEGAHVTWLPTAADGSVSATALREALQSHDDVALVSVMWANNEVGTILPIAEMSVVAMEFGVPMHSDAIQAVGQLPLDFGASGLSAMSVAGHKFGGPPGVGALLLRRDVTCVPLMHGGGQERDIRSGTPDVASAVGMATAAQIAVDGLEENSARLRLLRDRLVEGVLAEIDDVCLNGADDPMRLAGNAHFTFRGCEGDALLMLLDANGIECSTGSACTAGVAQPSHVLIAMGVDAASARGSLRLSLGHTSVEADVDAALEVLPGAVARARRAALAAAGASR
IscS-like cysteine desulfurase (EC 2.8.1.7)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
393
40,947
3D-structure;Aminotransferase;Iron;Iron-sulfur;Metal-binding;Pyridoxal phosphate;Reference proteome;Transferase
GO:0008483; GO:0016226; GO:0031071; GO:0046872; GO:0051536
Evidence at protein level
4
null
null
null
PF00266;
IPR000192;IPR016454;IPR015424;IPR015421;IPR015422;
4ISY;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
iscS Rv3025c
false
Mycobacterium tuberculosis
715
row_72381
false
null
181,459
H8EUF2
MRDAIPLGRIAGFVVNVHWSVLVILWLFTWSLATMLPGTVGGYPAVVYWLLGAGGAVMLLASLLAHELAHAVVARRAGVSVESVTLWLFGGVTALGGEAKTPKAAFRIAFAGPATSLALSATFGALAITLAGVRTPAIVISVAWWLATVNLLLGLFNLLPGAPLDGGRLVRAYLWRRHGDSVRAGIGAARAGRVVALVLIALGLAEFVAGGLVGGVWLAFIGWFIFAAAREEETRISTQQLFAGVRVADAMTAQPHTAPGWINVEDFIQRYVLGERHSAYPVADRDGSITGLVALRQLRDVAPSRRSTTSVGDIALPLHSVPTARPQEPLTALLERMAPLGPRSRALVTEGSAVVGIVTPSDVARLIDVYRLAQPEPTFTTSPQDADRFSDAG
Putative zinc metalloprotease Rip3
Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)
652,616
393
41,480
CBS domain;Cell membrane;Hydrolase;Membrane;Metal-binding;Metalloprotease;Protease;Repeat;Transmembrane;Transmembrane helix;Zinc
GO:0005886; GO:0006508; GO:0008237; GO:0046872
Evidence at transcript level
3
SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
null
TRANSMEM 10..30; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 45..65; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 77..97; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 108..128; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 136..156; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 207..227; /note="Helical"; /evidence="ECO:0000255"
PF00571;PF02163;
IPR000644;IPR046342;IPR008915;IPR016483;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
rip3 ERDMAN_2885
false
Mycobacterium tuberculosis
716
row_168516
false
null
212,376
P9WG69
MTTSVIVAGARTPIGKLMGSLKDFSASELGAIAIKGALEKANVPASLVEYVIMGQVLTAGAGQMPARQAAVAAGIGWDVPALTINKMCLSGIDAIALADQLIRAREFDVVVAGGQESMTKAPHLLMNSRSGYKYGDVTVLDHMAYDGLHDVFTDQPMGALTEQRNDVDMFTRSEQDEYAAASHQKAAAAWKDGVFADEVIPVNIPQRTGDPLQFTEDEGIRANTTAAALAGLKPAFRGDGTITAGSASQISDGAAAVVVMNQEKAQELGLTWLAEIGAHGVVAGPDSTLQSQPANAINKALDREGISVDQLDVVEINEAFAAVALASIRELGLNPQIVNVNGGAIAVGHPLGMSGTRITLHAALQLARRGSGVGVAALCGAGGQGDALILRAG
Probable acetyl-CoA acetyltransferase (EC 2.3.1.9) (Acetoacetyl-CoA thiolase) [Cleaved into: Probable acetyl-CoA acetyltransferase, propeptide removed]
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
393
40,469
Acyltransferase;Direct protein sequencing;Reference proteome;Transferase
GO:0003985; GO:0005576; GO:0005886
Evidence at protein level
3
null
null
null
PF02803;PF00108;
IPR002155;IPR016039;IPR020615;IPR020610;IPR020617;IPR020613;IPR020616;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
fadA4 Rv1323 MTCY130.08
false
Mycobacterium tuberculosis
717
row_198588
false
null
213,111
P9WPL3
MTTPGEDHAGSFYLPRLEYSTLPMAVDRGVGWKTLRDAGPVVFMNGWYYLTRREDVLAALRNPKVFSSRKALQPPGNPLPVVPLAFDPPEHTRYRRILQPYFSPAALSKALPSLRRHTVAMIDAIAGRGECEAMADLANLFPFQLFLVLYGLPLEDRDRLIGWKDAVIAMSDRPHPTEADVAAARELLEYLTAMVAERRRNPGPDVLSQVQIGEDPLSEIEVLGLSHLLILAGLDTVTAAVGFSLLELARRPQLRAMLRDNPKQIRVFIEEIVRLEPSAPVAPRVTTEPVTVGGMTLPAGSPVRLCMAAVNRDGSDAMSTDELVMDGKVHRHWGFGGGPHRCLGSHLARLELTLLVGEWLNQIPDFELAPDYAPEIRFPSKSFALKNLPLRWS
Cytochrome P450 143 (EC 1.14.-.-)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
393
43,541
3D-structure;Acetylation;Heme;Iron;Metal-binding;Monooxygenase;Oxidoreductase;Reference proteome
GO:0004497; GO:0005506; GO:0016705; GO:0020037
Evidence at protein level
3
null
null
null
PF00067;
IPR001128;IPR002397;IPR017972;IPR036396;
8AMO;8AMQ;8CKN;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
cyp143 Rv1785c MTV049.07c
false
Mycobacterium tuberculosis
718
row_199311
false
null
405,644
O53405
MSVMNGREVARESRDAQVFEFGTAPGSAVVKIPVQGGPIGGIAISRDGSLLVVTNNGTDTVSVVGTDTCRVTQTVTSVNEPFAIAMGNAEANRAYVSTVSSAYDAIAVIDVATNTVLGTHPLALSVSDLTLSPDDKYLYVSRNGTRGADVAVLDTTTGALIDVVDVSQAPGTTTQCVRMSPDGSVLYVGANGPSGGLLVVITTRAQSDGGRIGSRSRSRQKSSKPRGNQAAAGLRVVATIDIGSSVRDVALSPDGAIAYVASCGSDFGAVVDVIDTRTHQITSSRAISEIGGLVTRVSVSGDADRAYLVSEDRVTVLCTRTHDVIGTIRTGQPSCVVESPDGKYLYIADYSGTITRTAVASTIVSGTEQLALQRRGSMQWFSPELQQYAPALA
Seven-bladed beta-propeller protein Rv1057
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
393
40,711
Reference proteome;Stress response;Virulence
null
Evidence at protein level
2
null
null
null
null
IPR011048;IPR051200;IPR015943;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
Rv1057
false
Mycobacterium tuberculosis
719
row_388163
false
null
495,376
Q79FK6
MDFGALPPEVNSVRMYAGPGSAPMVAAASAWNGLAAELSSAATGYETVITQLSSEGWLGPASAAMAEAVAPYVAWMSAAAAQAEQAATQARAAAAAFEAAFAATVPPPLIAANRASLMQLISTNVFGQNTSAIAAAEAQYGEMWAQDSAAMYAYAGSSASASAVTPFSTPPQIANPTAQGTQAAAVATAAGTAQSTLTEMITGLPNALQSLTSPLLQSSNGPLSWLWQILFGTPNFPTSISALLTDLQPYASFFYNTEGLPYFSIGMGNNFIQSAKTLGLIGSAAPAAVAAAGDAAKGLPGLGGMLGGGPVAAGLGNAASVGKLSVPPVWSGPLPGSVTPGAAPLPVSTVSAAPEAAPGSLLGGLPLAGAGGAGAGPRYGFRPTVMARPPFAG
PPE family protein PPE26
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
393
38,589
Reference proteome;Virulence
GO:0052572
Evidence at protein level
2
null
null
null
PF00823;PF12484;
IPR022171;IPR000030;IPR038332;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
PPE26 Rv1789
false
Mycobacterium tuberculosis
720
row_476163
false
null
544,656
P64750
MPSRATVQEFSDSYPFCHNGFRPIMMPKIVSVQHSTRRHLTSFVGRKAELNDVRRLLSDKRLVTLTGPDGMGKSRLALQIGAQIAHEFTYGRWDCDLATVTDRDCVSISMLNALGLPVQPGLSAIDTLVGVINDARVLLVLDHCEHLLDACAAIIDSLLRSCPRLTILTTSTEAIGLAGELTWRVPPLSLTNDAIELFVDRARRVRSDFAINADTAVTVGEICRRLDGVPLAIELAAARTDTLSPVEILAGLNDRFRLVAGAAGNAVRPEQTLCATVQWSHALLSGPERALLHRLAVFAGGFDLDGAQAVGANDEDFEGYQTLGRFAELVDKAFVVVENNRGRAGYRLLYSVRQYALEKLSESGEADAVLARYRKHLKQPNQVVRAGSGGVRY
Uncharacterized protein Mb0918
Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
233,413
393
42,873
ATP-binding;Nucleotide-binding;Reference proteome
GO:0005524
Predicted
1
null
null
null
null
IPR027417;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype)
BQ2027_MB0918
false
Mycobacterium tuberculosis
721
row_524899
false
null
26,861
P9WJE1
MSRAFIIDPTISAIDGLYDLLGIGIPNQGGILYSSLEYFEKALEELAAAFPGDGWLGSAADKYAGKNRNHVNFFQELADLDRQLISLIHDQANAVQTTRDILEGAKKGLEFVRPVAVDLTYIPVVGHALSAAFQAPFCAGAMAVVGGALAYLVVKTLINATQLLKLLAKLAELVAAAIADIISDVADIIKGTLGEVWEFITNALNGLKELWDKLTGWVTGLFSRGWSNLESFFAGVPGLTGATSGLSQVTGLFGAAGLSASSGLAHADSLASSASLPALAGIGGGSGFGGLPSLAQVHAASTRQALRPRADGPVGAAAEQVGGQSQLVSAQGSQGMGGPVGMGGMHPSSGASKGTTTKKYSEGAAAGTEDAERAPVEADAGGGQKVLVRNVV
ESX-1 secretion-associated protein EspA
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
392
39,888
Disulfide bond;Reference proteome;Secreted;Virulence
GO:0005576; GO:0005615; GO:0005886; GO:0044315; GO:0051701; GO:0071766
Evidence at protein level
5
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:16030141, ECO:0000269|PubMed:20585630, ECO:0000269|PubMed:22155774}. Note=Secreted via the ESX-1 / type VII secretion system (T7SS) (PubMed:16030141). Secretion of EspA, EsxA and EsxB is mutually dependent (PubMed:16030141). {ECO:0000269|PubMed:16030141}.
null
null
PF18879;
IPR043796;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
espA Rv3616c
false
Mycobacterium tuberculosis
722
row_23504
false
null
26,934
P9WMN7
MSTSLPPLVEPASALSREEVARYSRHLIIPDLGVDGQKRLKNARVLVIGAGGLGAPTLLYLAAAGVGTIGIVDFDVVDESNLQRQVIHGVADVGRSKAQSARDSIVAINPLIRVRLHELRLAPSNAVDLFKQYDLILDGTDNFATRYLVNDAAVLAGKPYVWGSIYRFEGQASVFWEDAPDGLGVNYRDLYPEPPPPGMVPSCAEGGVLGIICASVASVMGTEAIKLITGIGETLLGRLLVYDALEMSYRTITIRKDPSTPKITELVDYEQFCGVVADDAAQAAKGSTITPRELRDWLDSGRKLALIDVRDPVEWDIVHIDGAQLIPKSLINSGEGLAKLPQDRTAVLYCKTGVRSAEALAAVKKAGFSDAVHLQGGIVAWAKQMQPDMVMY
Probable adenylyltransferase/sulfurtransferase MoeZ [Includes: Sulfur carrier protein CysO adenylyltransferase (EC 2.7.7.-); Sulfur carrier protein CysO sulfurtransferase (EC 2.8.1.-)]
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
392
42,173
ATP-binding;Membrane;Multifunctional enzyme;Nucleotide-binding;Nucleotidyltransferase;Reference proteome;Transferase;Transmembrane;Transmembrane helix
GO:0004792; GO:0005524; GO:0005737; GO:0005829; GO:0006535; GO:0008146; GO:0008641; GO:0009274; GO:0016020; GO:0016779; GO:0016782; GO:0019344; GO:0042783
Evidence at protein level
5
SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
null
TRANSMEM 45..65; /note="Helical"; /evidence="ECO:0000255"
PF00581;PF00899;
IPR001763;IPR036873;IPR045886;IPR000594;IPR035985;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
moeZ moeB1 Rv3206c
false
Mycobacterium tuberculosis
723
row_23575
false
null
4,119
I6XHI4
MGYPVIVEATRSPIGKRNGWLSGLHATELLGAVQKAVVDKAGIQSGLHAGDVEQVIGGCVTQFGEQSNNISRVAWLTAGLPEHVGATTVDCQCGSGQQANHLIAGLIAAGAIDVGIACGIEAMSRVGLGANAGPDRSLIRAQSWDIDLPNQFEAAERIAKRRGITREDVDVFGLESQRRAQRAWAEGRFDREISPIQAPVLDEQNQPTGERRLVFRDQGLRETTMAGLGELKPVLEGGIHTAGTSSQISDGAAAVLWMDEAVARAHGLTPRARIVAQALVGAEPYYHLDGPVQSTAKVLEKAGMKIGDIDIVEINEAFASVVLSWARVHEPDMDRVNVNGGAIALGHPVGCTGSRLITTALHELERTDQSLALITMCAGGALSTGTIIERI
Steroid 3-ketoacyl-CoA thiolase (EC 2.3.1.16) (Acetyl-CoA acetyltransferase FadA5) (Beta-ketoacyl-CoA thiolase)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
391
41,329
3D-structure;Acyltransferase;Cholesterol metabolism;Lipid degradation;Lipid metabolism;Reference proteome;Steroid metabolism;Sterol metabolism;Transferase;Virulence
GO:0003988; GO:0006635; GO:0006707; GO:0010124; GO:0042802
Evidence at protein level
5
null
null
null
PF02803;PF00108;
IPR002155;IPR016039;IPR020617;IPR020613;IPR020616;
4UBT;4UBU;4UBV;4UBW;5ONC;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
fadA5 Rv3546
false
Mycobacterium tuberculosis
724
row_3268
false
null
26,717
P9WFZ5
MRKLGPVTIDPRRHDAVLFDTTLDATQELVRQLQEVGVGTGVFGSGLDVPIVAAGRLAVRPGRCVVVSAHSAGVTAARESGFALIIGVDRTGCRDALRRDGADTVVTDLSEVSVRTGDRRMSQLPDALQALGLADGLVARQPAVFFDFDGTLSDIVEDPDAAWLAPGALEALQKLAARCPIAVLSGRDLADVTQRVGLPGIWYAGSHGFELTAPDGTHHQNDAAAAAIPVLKQAAAELRQQLGPFPGVVVEHKRFGVAVHYRNAARDRVGEVAAAVRTAEQRHALRVTTGREVIELRPDVDWDKGKTLLWVLDHLPHSGSAPLVPIYLGDDITDEDAFDVVGPHGVPIVVRHTDDGDRATAALFALDSPARVAEFTDRLARQLREAPLRAT
Trehalose-phosphate phosphatase (TPP) (EC 3.1.3.12) (Trehalose-6-phosphate phosphatase)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
391
41,720
3D-structure;Hydrolase;Magnesium;Manganese;Metal-binding;Reference proteome
GO:0000287; GO:0004805; GO:0005829; GO:0005886; GO:0005992; GO:0016311
Evidence at protein level
5
null
null
null
PF02358;
IPR036412;IPR006379;IPR023214;IPR044651;IPR003337;
5GVX;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
otsB otsB2 Rv3372
false
Mycobacterium tuberculosis
725
row_23364
false
null
26,802
P9WI31
MDFGALPPEINSARMYAGAGAGPMMAAGAAWNGLAAELGTTAASYESVITRLTTESWMGPASMAMVAAAQPYLAWLTYTAEAAAHAGSQAMASAAAYEAAYAMTVPPEVVAANRALLAALVATNVLGINTPAIMATEALYAEMWAQDALAMYGYAAASGAAGMLQPLSPPSQTTNPGGLAAQSAAVGSAAATAAVNQVSVADLISSLPNAVSGLASPVTSVLDSTGLSGIIADIDALLATPFVANIINSAVNTAAWYVNAAIPTAIFLANALNSGAPVAIAEGAIEAAEGAASAAAAGLADSVTPAGLGASLGEATLVGRLSVPAAWSTAAPATTAGATALEGSGWTVAAEEAGPVTGMMPGMASAAKGTGAYAGPRYGFKPTVMPKQVVV
PPE family protein PPE15 (Mycobacterial perilipin-1) (MPER1)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
391
38,081
3D-structure;Host mitochondrion;Reference proteome;Secreted;Virulence
GO:0005576; GO:0033650; GO:0052572
Evidence at protein level
5
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:38408543}. Host mitochondrion {ECO:0000269|PubMed:38615303}.
null
null
PF00823;PF12484;
IPR022171;IPR000030;IPR038332;
5XFS;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
PPE15 mper1 Rv1039c
false
Mycobacterium tuberculosis
726
row_23448
false
null
181,884
L7N675
MVDFGALPPEINSARMYAGPGSASLVAAAQMWDSVASDLFSAASAFQSVVWGLTVGSWIGSSAGLMVAAASPYVAWMSVTAGQAELTAAQVRVAAAAYETAYGLTVPPPVIAENRAELMILIATNLLGQNTPAIAVNEAEYGEMWAQDAAAMFGYAAATATATATLLPFEEAPEMTSAGGLLEQAAAVEEASDTAAANQLMNNVPQALQQLAQPTQGTTPSSKLGGLWKTVSPHRSPISNMVSMANNHMSMTNSGVSMTNTLSSMLKGFAPAAAAQAVQTAAQNGVRAMSSLGSSLGSSGLGGGVAANLGRAASVGSLSVPQAWAAANQAVTPAARALPLTSLTSAAERGPGQMLGGLPVGQMGARAGGGLSGVLRVPPRPYVMPHSPAAG
PPE family protein PPE18
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
391
39,158
Cell wall;Reference proteome;Secreted;Virulence
GO:0005576; GO:0009986; GO:0052572
Evidence at protein level
3
SUBCELLULAR LOCATION: Secreted, cell wall {ECO:0000269|PubMed:19880448}. Cell surface {ECO:0000269|PubMed:19880448}.
null
null
PF00823;PF12484;
IPR022171;IPR000030;IPR038332;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
PPE18 Rv1196
false
Mycobacterium tuberculosis
727
row_168921
false
null
212,671
P9WJ78
MTSPVPRLIEQFERGLDAPICLTWELTYACNLACVHCLSSSGKRDPGELSTRQCKDIIDELERMQVFYVNIGGGEPTVRPDFWELVDYATAHHVGVKFSTNGVRITPEVATRLAATDYVDVQISLDGATAEVNDAIRGTGSFDMAVRALQNLAAAGFAGVKISVVITRRNVAQLDEFATLASRYGATLRITRLRPSGRGTDVWADLHPTADQQVQLYDWLVSKGERVLTGDSFFHLAPLGQSGALAGLNMCGAGRVVCLIDPVGDVYACPFAIHDHFLAGNVLSDGGFQNVWKNSSLFRELREPQSAGACGSCGHYDSCRGGCMAAKFFTGLPLDGPDPECVQGHSEPALARERHLPRPRADHSRGRRVSKPVPLTLSMRPPKRPCNESPV
Mycofactocin maturase MftC ([Mycofactocin precursor peptide]-pyrrolidinone derivative synthase) (EC 4.1.99.26) ([Mycofactocin precursor peptide]-tyrosine decarboxylase) (EC 1.3.98.7)
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
83,331
391
42,448
4Fe-4S;Iron;Iron-sulfur;Lyase;Metal-binding;Oxidoreductase;Reference proteome;S-adenosyl-L-methionine
GO:0016491; GO:0016829; GO:0046872; GO:0051539
Inferred from homology
3
null
null
null
PF04055;PF13186;
IPR023885;IPR013785;IPR034391;IPR006638;IPR023913;IPR017200;IPR050377;IPR007197;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
mftC MT0720
false
Mycobacterium tuberculosis
728
row_198878
false
null
546,495
P9WHY4
MVLGFSWLPPEINSARMFAGAGSGPLFAAASAWEGLAADLWASASSFESVLAALTTGPWTGPASMSMAAAASPYVGWLSTVASQAQLAAIQARAAATAFEAALAATVHPTAVTANRVSLASLIAANVLGQNTPAIAATEFDYLEMWAQDVAAMVGYHAGAKSVAATLAPFSLPPVSLAGLAAQVGTQVAGMATTASAAVTPVVEGAMASVPTVMSGMQSLVSQLPLQHASMLFLPVRILTSPITTLASMARESATRLGPPAGGLAAANTPNPSGAAIPAFKPLGGRELGAGMSAGLGQAQLVGSMSVPPTWQGSIPISMASSAMSGLGVPPNPVALTQAAGAAGGGMPMMLMPMSISGAGAGMPGGLMDRDGAGWHVTQARLTVIPRTGVG
Uncharacterized PPE family protein PPE49
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
83,331
391
38,586
Reference proteome
GO:0052572
Inferred from homology
1
null
null
null
PF00823;PF12484;
IPR022171;IPR000030;IPR038332;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
PPE49 MT3209
false
Mycobacterium tuberculosis
729
row_526590
false
null