Unnamed: 0
int64 2
562k
| Entry
stringlengths 6
10
| Sequence
stringlengths 11
999
| Protein names
stringlengths 5
558
| Organism
stringclasses 392
values | Organism (ID)
int64 595
2.89M
| Length
int64 11
999
| Mass
int64 1.06k
118k
| Keywords
stringlengths 4
380
⌀ | Gene Ontology IDs
stringlengths 10
754
⌀ | Protein existence
stringclasses 5
values | Annotation
float64 1
5
| Subcellular location [CC]
stringlengths 30
2.26k
⌀ | Signal peptide
stringclasses 677
values | Transmembrane
stringlengths 32
2.52k
⌀ | Pfam
stringlengths 8
72
⌀ | InterPro
stringlengths 10
180
⌀ | PDB
stringlengths 5
2.65k
⌀ | Taxonomic lineage
stringclasses 178
values | Gene Names
stringlengths 2
299
⌀ | Toxin
bool 2
classes | species
stringclasses 111
values | cdhit_cluster
int64 0
4.65k
| cdhit_rep
stringlengths 5
10
| cdhit_rep_is_ref
bool 1
class | cdhit_pct_id
float64 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
27,088 |
P9WQN9
|
MTFFEQVRRLRSAATTLPRRLAIAAMGAVLVYGLVGTFGGPATAGAFSRPGLPVEYLQVPSASMGRDIKVQFQGGGPHAVYLLDGLRAQDDYNGWDINTPAFEEYYQSGLSVIMPVGGQSSFYTDWYQPSQSNGQNYTYKWETFLTREMPAWLQANKGVSPTGNAAVGLSMSGGSALILAAYYPQQFPYAASLSGFLNPSEGWWPTLIGLAMNDSGGYNANSMWGPSSDPAWKRNDPMVQIPRLVANNTRIWVYCGNGTPSDLGGDNIPAKFLEGLTLRTNQTFRDTYAADGGRNGVFNFPPNGTHSWPYWNEQLVAMKADIQHVLNGATPPAAPAAPAA
|
Diacylglycerol acyltransferase/mycolyltransferase Ag85C (DGAT) (EC 2.3.1.122) (EC 2.3.1.20) (Acyl-CoA:diacylglycerol acyltransferase) (Antigen 85 complex C) (85C) (Ag85C) (Fibronectin-binding protein C) (Fbps C)
|
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
| 83,332 | 340 | 36,771 |
3D-structure;Acyltransferase;Direct protein sequencing;Reference proteome;Secreted;Signal;Transferase
|
GO:0004144; GO:0005576; GO:0006869; GO:0009247; GO:0009274; GO:0016020; GO:0016747; GO:0035375; GO:0046677; GO:0050348; GO:0071769
|
Evidence at protein level
| 5 |
SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
|
SIGNAL 1..45; /evidence="ECO:0000255"
| null |
PF00756;
|
IPR029058;IPR000801;IPR050583;
|
1DQY;1DQZ;1VA5;3HRH;4MQL;4MQM;4QDO;4QDT;4QDU;4QDX;4QDZ;4QE3;4QEK;5KWI;5KWJ;5OCJ;5VNS;7MYG;
|
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
|
fbpC mpt45 Rv0129c MTCI5.03c
| false |
Mycobacterium tuberculosis
| 930 |
row_23721
| false | null |
81,824 |
P9WKX5
|
MVATTSSGGSSVGWPSRLSGVRLHLVTGKGGTGKSTIAAALALTLAAGGRKVLLVEVEGRQGIAQLFDVPPLPYQELKIATAERGGQVNALAIDIEAAFLEYLDMFYNLGIAGRAMRRIGAVEFATTIAPGLRDVLLTGKIKETVVRLDKNKLPVYDAIVVDAPPTGRIARFLDVTKAVSDLAKGGPVHAQSEGVVKLLHSNQTAIHLVTLLEALPVQETLEAIEELAQMELPIGSVIVNRNIPAHLEPQDLAKAAEGEVDADSVRAGLLTAGVKLPDADFAGLLTETIQHATRITARAEIAQQLDALQVPRLELPTVSDGVDLGSLYELSESLAQQGVR
|
ATPase BagA (EC 3.6.1.-) (ATPase Rv3679) (Bacterial Get3-like protein A)
|
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
| 83,332 | 340 | 35,856 |
3D-structure;ATP-binding;Hydrolase;Nucleotide-binding;Reference proteome
|
GO:0005524; GO:0005886; GO:0016887
|
Evidence at protein level
| 4 | null | null | null |
PF02374;
|
IPR025723;IPR016300;IPR027417;
|
6BS3;6BS4;6BS5;
|
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
|
bagA Rv3679 MTV025.027
| false |
Mycobacterium tuberculosis
| 931 |
row_72270
| false | null |
81,837 |
P9WMJ3
|
MELGSLIRATNLWGYTDLMRELGADPLPFLRRFDIPPGIEHQEDAFMSLAGFVRMLEASAAELDCPDFGLRLARWQGLGILGPVAVIARNAATLFGGLEAIGRYLYVHSPALTLTVSSTTARSNVRFGYEVTEPGIPYPLQGYELSMANAARMIRLLGGPQARARVFSFRHAQLGTDAAYREALGCTVRFGRTWCGFEVDHRLAGRPIDHADPETKRIATKYLESQYLPSDATLSERVVGLARRLLPTGQCSAEAIADQLDMHPRTLQRRLAAEGLRCHDLIERERRAQAARYLAQPGLYLSQIAVLLGYSEQSALNRSCRRWFGMTPRQYRAYGGVSGR
|
HTH-type transcriptional regulator VirS (Virulence-regulating protein VirS)
|
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
| 83,332 | 340 | 37,789 |
3D-structure;DNA-binding;Phosphoprotein;Reference proteome;Transcription;Transcription regulation;Virulence
|
GO:0000976; GO:0003700; GO:0005829; GO:0045893; GO:0071468
|
Evidence at protein level
| 4 | null | null | null |
PF12625;PF12833;
|
IPR032687;IPR009057;IPR018060;
|
8RCW;
|
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
|
virS Rv3082c MTV013.03c
| false |
Mycobacterium tuberculosis
| 932 |
row_72283
| false | null |
425,804 |
P65024
|
MRWARQAVAVNGMPVDDGALPGLQRIGLVRSVRAPQFDGITFHEVLCKSALNKVPNAAALPFRYTVNGYRGCSHACRYCFARPTHEYLDFNPGTDFDTQVVVKTNVAAVLRHELRRPSWRRETVALGTNTDPYQRAEGRYALMPGIIGALAASGTPLSILTKGTLLRRDLPLIAEAAQQVPVSVAVSLAVGDPELHRDVESGTPTPQARLALITAIRAAGLDCHVMVAPVLPQLTDSGEHLDQLLGQIAAAGATGVTVFGLHLRGSTRGWFMCWLARAHPELVSRYRELYRRGPYLPPSYREMLRERVAPLIAKYRLAGDHRPAPPETEAALVPVQATLF
|
Uncharacterized protein Mb2609c
|
Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
| 233,413 | 340 | 37,176 |
4Fe-4S;Cell membrane;Iron;Iron-sulfur;Membrane;Metal-binding;Reference proteome;S-adenosyl-L-methionine;Transmembrane;Transmembrane helix
|
GO:0003824; GO:0005886; GO:0046872; GO:0051539
|
Predicted
| 2 |
SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
| null |
TRANSMEM 140..160; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 243..263; /note="Helical"; /evidence="ECO:0000255"
|
PF04055;
|
IPR006638;IPR040086;IPR007197;
| null |
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype)
|
BQ2027_MB2609C
| false |
Mycobacterium tuberculosis
| 933 |
row_407898
| false | null |
539,494 |
P0A5D6
|
MDRTRIVRRWRRNMDVADDAEYVEMLATLSEGSVRRNFNPYTDIDWESPEFAVTDNDPRWILPATDPLGRHPWYQAQSRERQIEIGMWRQANVAKVGLHFESILIRGLMNYTFWMPNGSPEYRYCLHESVEECNHTMMFQEMVNRVGADVPGLPRRLRWVSPLVPLVAGPLPVAFFIGVLAGEEPIDHTQKNVLREGKSLHPIMERVMSIHVAEEARHISFAHEYLRKRLPRLTRMQRFWISLYFPLTMRSLCNAIVVPPKAFWEEFDIPREVKKELFFGSPESRKWLCDMFADARMLAHDTGLMNPIARLVWRLCKIDGKPSRYRSEPQRQHLAAAPAA
|
Uncharacterized protein Mb0909
|
Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
| 233,413 | 340 | 39,798 |
Cell membrane;Membrane;Reference proteome;Transmembrane;Transmembrane helix
|
GO:0005886; GO:0016491
|
Predicted
| 1 |
SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
| null |
TRANSMEM 162..182; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 239..259; /note="Helical"; /evidence="ECO:0000255"
|
PF11583;
|
IPR025859;IPR009078;IPR012348;
| null |
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype)
|
BQ2027_MB0909
| false |
Mycobacterium tuberculosis
| 934 |
row_519783
| false | null |
544,682 |
P64832
|
MGGARRLKLDGSIPNQLARAADAAVALERNGFDGGWTAEASHDPFLPLLLAAEHTSRLELGTNIAVAFARNPMIVANVGWDLQTYSKGRLILGLGTQIRPHIEKRFSMPWGHPARRMREFVAALRAIWLAWQDGTKLCFEGEFYTHKIMTPMFTPEPQPYPVPRVFIAAVGEAMTEMCGEVADGHLGHPMVSKRYLTEVSVPALLRGLARSGRDRSAFEVSCEVMVATGADDAELAAACTATRKQIAFYGSTPAYRKVLEQHGWGDLHPELHRLSKLGEWEAMGGLIDDEMLGAFAVVGPVDTIAGALRNRCEGVVDRVLPIFMAASQECINAALQDFRR
|
Uncharacterized protein Mb1395
|
Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
| 233,413 | 340 | 37,252 |
Reference proteome;Signal
|
GO:0016705
|
Inferred from homology
| 1 | null |
SIGNAL 1..20; /evidence="ECO:0000255"
| null |
PF00296;
|
IPR050564;IPR019919;IPR011251;IPR036661;
| null |
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype)
|
BQ2027_MB1395
| false |
Mycobacterium tuberculosis
| 935 |
row_524925
| false | null |
25,348 |
P71857
|
MDFDPTAEQQAVADVVTSVLERDISWEALVCGGVTALPVPERLGGDGVGLFEVGALLTEVGRHGAVTPALATLGLGVVPLLELASAEQQDRFLAGVAKGGVLTAALNEPGAALPDRPATSFVGGRLSGTKVGVGYAEQADWMLVTADNAVVVVSPTADGVRMVRTPTSNGSDEYVMTMDGVAVADCDILADVAAHRVNQLALAVMGAYADGLVAGALRLTADYVANRKQFGKPLSTFQTVAAQLAEVYIASRTIDLVAKSVIWRLAEDLDAGDDLGVLGYWVTSQAPPAMQICHHLHGGMGMDVTYPMHRYYSTIKDLTRLLGGPSHRLELLGARCSLT
|
Acyl-CoA dehydrogenase FadE28 (ACAD) (EC 1.3.99.-) (3-oxo-23,24-bisnorchol-4-en-22-oyl-CoA dehydrogenase alpha subunit) (3-oxo-4-pregnene-20-carboxyl-CoA dehydrogenase alpha subunit)
|
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
| 83,332 | 339 | 35,469 |
Cholesterol metabolism;FAD;Flavoprotein;Lipid degradation;Lipid metabolism;NAD;NADP;Oxidoreductase;Reference proteome;Steroid metabolism;Sterol metabolism;Virulence
|
GO:0003995; GO:0006707; GO:0009268; GO:0033539; GO:0051701; GO:0071949
|
Evidence at protein level
| 5 | null | null | null |
PF00441;PF02771;
|
IPR046373;IPR036250;IPR009075;IPR013786;IPR037069;IPR009100;
| null |
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
|
fadE28 Rv3544c
| false |
Mycobacterium tuberculosis
| 936 |
row_22144
| false | null |
26,824 |
P9WID3
|
MTEPAAWDEGKPRIITLTMNPALDITTSVDVVRPTEKMRCGAPRYDPGGGGINVARIVHVLGGCSTALFPAGGSTGSLLMALLGDAGVPFRVIPIAASTRESFTVNESRTAKQYRFVLPGPSLTVAEQEQCLDELRGAAASAAFVVASGSLPPGVAADYYQRVADICRRSSTPLILDTSGGGLQHISSGVFLLKASVRELRECVGSELLTEPEQLAAAHELIDRGRAEVVVVSLGSQGALLATRHASHRFSSIPMTAVSGVGAGDAMVAAITVGLSRGWSLIKSVRLGNAAGAAMLLTPGTAACNRDDVERFFELAAEPTEVGQDQYVWHPIVNPEASP
|
ATP-dependent 6-phosphofructokinase isozyme 2 (ATP-PFK 2) (Phosphofructokinase 2) (EC 2.7.1.11) (Phosphofructokinase B) (Phosphohexokinase 2) (Tagatose-6-phosphate kinase) (EC 2.7.1.144)
|
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
| 83,332 | 339 | 35,401 |
Acetylation;ATP-binding;Glycolysis;Isopeptide bond;Kinase;Magnesium;Metal-binding;Nucleotide-binding;Potassium;Reference proteome;Transferase;Ubl conjugation
|
GO:0003872; GO:0005524; GO:0005829; GO:0009024; GO:0046872
|
Evidence at protein level
| 5 | null | null | null |
PF00294;
|
IPR002173;IPR011611;IPR029056;IPR017583;
| null |
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
|
pfkB Rv2029c
| false |
Mycobacterium tuberculosis
| 937 |
row_23469
| false | null |
26,958 |
P9WN83
|
MTVRVGINGFGRIGRNFYRALLAQQEQGTADVEVVAANDITDNSTLAHLLKFDSILGRLPCDVGLEGDDTIVVGRAKIKALAVREGPAALPWGDLGVDVVVESTGLFTNAAKAKGHLDAGAKKVIISAPATDEDITIVLGVNDDKYDGSQNIISNASCTTNCLAPLAKVLDDEFGIVKGLMTTIHAYTQDQNLQDGPHKDLRRARAAALNIVPTSTGAAKAIGLVMPQLKGKLDGYALRVPIPTGSVTDLTVDLSTRASVDEINAAFKAAAEGRLKGILKYYDAPIVSSDIVTDPHSSIFDSGLTKVIDDQAKVVSWYDNEWGYSNRLVDLVTLVGKSL
|
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) (EC 1.2.1.12) (NAD-dependent glyceraldehyde-3-phosphate dehydrogenase)
|
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
| 83,332 | 339 | 35,956 |
3D-structure;Cytoplasm;Glycolysis;NAD;Nucleotide-binding;Oxidoreductase;Reference proteome
|
GO:0004365; GO:0005576; GO:0005829; GO:0005886; GO:0006006; GO:0006096; GO:0009274; GO:0050661; GO:0051287
|
Evidence at protein level
| 5 |
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
| null | null |
PF02800;PF00044;
|
IPR020831;IPR020830;IPR020829;IPR020828;IPR006424;IPR036291;
|
8BR4;
|
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
|
gap Rv1436 MTCY493.18c
| false |
Mycobacterium tuberculosis
| 938 |
row_23598
| false | null |
81,914 |
P9WPH0
|
MNVEQVKSIDEAMGLAIEHSYQVKGTTYPKPPVGAVIVDPNGRIVGAGGTEPAGGDHAEVVALRRAGGLAAGAIVVVTMEPCNHYGKTPPCVNALIEARVGTVVYAVADPNGIAGGGAGRLSAAGLQVRSGVLAEQVAAGPLREWLHKQRTGLPHVTWKYATSIDGRSAAADGSSQWISSEAARLDLHRRRAIADAILVGTGTVLADDPALTARLADGSLAPQQPLRVVVGKRDIPPEARVLNDEARTMMIRTHEPMEVLRALSDRTDVLLEGGPTLAGAFLRAGAINRILAYVAPILLGGPVTAVDDVGVSNITNALRWQFDSVEKVGPDLLLSLVAR
|
Riboflavin biosynthesis protein RibD [Includes: Diaminohydroxyphosphoribosylaminopyrimidine deaminase (DRAP deaminase) (EC 3.5.4.26) (Riboflavin-specific deaminase); 5-amino-6-(5-phosphoribosylamino)uracil reductase (EC 1.1.1.193) (HTP reductase)]
|
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
| 83,331 | 339 | 35,367 |
Hydrolase;Metal-binding;Multifunctional enzyme;NADP;Oxidoreductase;Reference proteome;Riboflavin biosynthesis;Zinc
|
GO:0008270; GO:0008703; GO:0008835; GO:0009231
|
Inferred from homology
| 4 | null | null | null |
PF00383;PF01872;
|
IPR016192;IPR002125;IPR016193;IPR024072;IPR004794;IPR002734;IPR050765;
| null |
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
|
ribD ribG MT1453
| false |
Mycobacterium tuberculosis
| 939 |
row_72354
| false | null |
27,090 |
P9WQP3
|
MQLVDRVRGAVTGMSRRLVVGAVGAALVSGLVGAVGGTATAGAFSRPGLPVEYLQVPSPSMGRDIKVQFQSGGANSPALYLLDGLRAQDDFSGWDINTPAFEWYDQSGLSVVMPVGGQSSFYSDWYQPACGKAGCQTYKWETFLTSELPGWLQANRHVKPTGSAVVGLSMAASSALTLAIYHPQQFVYAGAMSGLLDPSQAMGPTLIGLAMGDAGGYKASDMWGPKEDPAWQRNDPLLNVGKLIANNTRVWVYCGNGKPSDLGGNNLPAKFLEGFVRTSNIKFQDAYNAGGGHNGVFDFPDSGTHSWEYWGAQLNAMKPDLQRALGATPNTGPAPQGA
|
Diacylglycerol acyltransferase/mycolyltransferase Ag85A (DGAT) (EC 2.3.1.122) (EC 2.3.1.20) (Acyl-CoA:diacylglycerol acyltransferase) (Antigen 85 complex A) (85A) (Ag85A) (Fibronectin-binding protein A) (Fbps A)
|
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
| 83,332 | 338 | 35,686 |
3D-structure;Acyltransferase;Cell wall;Cytoplasm;Direct protein sequencing;Disulfide bond;Reference proteome;Secreted;Signal;Transferase
|
GO:0004144; GO:0005576; GO:0005737; GO:0005886; GO:0009274; GO:0016747; GO:0035375; GO:0050348
|
Evidence at protein level
| 5 |
SUBCELLULAR LOCATION: Secreted, cell wall. Cytoplasm.
|
SIGNAL 1..43; /note="Tat-type signal"; /evidence="ECO:0000255"
| null |
PF00756;
|
IPR029058;IPR000801;IPR050583;IPR006311;
|
1SFR;
|
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
|
fbpA mpt44 Rv3804c MTV026.09c
| false |
Mycobacterium tuberculosis
| 940 |
row_23723
| false | null |
213,038 |
P9WNZ6
|
MSAKLTDLQLLHELEPVVEKYLNRHLSMHKPWNPHDYIPWSDGKNYYALGGQDWDPDQSKLSDVAQVAMVQNLVTEDNLPSYHREIAMNMGMDGAWGQWVNRWTAEENRHGIALRDYLVVTRSVDPVELEKLRLEVVNRGFSPGQNHQGHYFAESLTDSVLYVSFQELATRISHRNTGKACNDPVADQLMAKISADENLHMIFYRDVSEAAFDLVPNQAMKSLHLILSHFQMPGFQVPEFRRKAVVIAVGGVYDPRIHLDEVVMPVLKKWRIFEREDFTGEGAKLRDELALVIKDLELACDKFEVSKQRQLDREARTGKKVSAHELHKTAGKLAMSRR
|
Putative acyl-[acyl-carrier-protein] desaturase DesA1 (Putative acyl-ACP desaturase DesA1) (EC 1.14.19.-)
|
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
| 83,331 | 338 | 38,770 |
Fatty acid biosynthesis;Fatty acid metabolism;Iron;Lipid biosynthesis;Lipid metabolism;Metal-binding;Oxidoreductase;Reference proteome
|
GO:0005829; GO:0006633; GO:0009986; GO:0045300; GO:0046872
|
Inferred from homology
| 3 |
SUBCELLULAR LOCATION: Cell surface {ECO:0000250|UniProtKB:P9WNZ7}.
| null | null |
PF03405;
|
IPR005067;IPR009078;IPR012348;
| null |
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
|
desA1 des MT0846
| false |
Mycobacterium tuberculosis
| 941 |
row_199238
| false | null |
213,106 |
P9WPJ5
|
MVQLYVSDSVSRISFADGRVIVWSEELGESQYPIETLDGITLFGRPTMTTPFIVEMLKRERDIQLFTTDGHYQGRISTPDVSYAPRLRQQVHRTDDPAFCLSLSKRIVSRKILNQQALIRAHTSGQDVAESIRTMKHSLAWVDRSGSLAELNGFEGNAAKAYFTALGHLVPQEFAFQGRSTRPPLDAFNSMVSLGYSLLYKNIIGAIERHSLNAYIGFLHQDSRGHATLASDLMEVWRAPIIDDTVLRLIADGVVDTRAFSKNSDTGAVFATREATRSIARAFGNRIARTATYIKGDPHRYTFQYALDLQLQSLVRVIEAGHPSRLVDIDITSEPSGA
|
CRISPR-associated endonuclease Cas1 (EC 3.1.-.-)
|
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
| 83,332 | 338 | 37,664 |
Antiviral defense;DNA-binding;Endonuclease;Hydrolase;Magnesium;Manganese;Metal-binding;Nuclease;Reference proteome
|
GO:0003677; GO:0004519; GO:0009274; GO:0043571; GO:0046872; GO:0051607; GO:0099048
|
Evidence at protein level
| 3 | null | null | null |
PF01867;
|
IPR050646;IPR002729;IPR042206;IPR042211;
| null |
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
|
cas1 Rv2817c
| false |
Mycobacterium tuberculosis
| 942 |
row_199306
| false | null |
410,001 |
P0A629
|
MLARAGEVGRAGPAIRWLGGIGAVIPLLALVLVLVVLVIEAMGAIRLNGLHFFTATEWNPGNTYGETVVTDGVAHPVGAYYGALPLIVGTLATSAIALIIAVPVSVGAALVIVERLPKRLAEAVGIVLELLAGIPSVVVGLWGAMTFGPFIAHHIAPVIAHNAPDVPVLNYLRGDPGNGEGMLVSGLVLAVMVVPIIATTTHDLFRQVPVLPREGAIALGMSNWECVRRVTLPWVSSGIVGAVVLGLGRALGETMAVAMVSGAVLGAMPANIYATMTTIAATIVSQLDSAMTDSTNFAVKTLAEVGLVLMVITLLTNVAARGMVRRVSRTALPVGRGI
|
Phosphate transport system permease protein PstC 1
|
Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
| 233,413 | 338 | 34,793 |
Cell membrane;Membrane;Phosphate transport;Reference proteome;Transmembrane;Transmembrane helix;Transport
|
GO:0005315; GO:0005886; GO:0006817
|
Inferred from homology
| 2 |
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000255|PROSITE-ProRule:PRU00441}.
| null |
TRANSMEM 19..39; /note="Helical"; /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"; TRANSMEM 93..113; /note="Helical"; /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"; TRANSMEM 123..143; /note="Helical"; /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"; TRANSMEM 144..164; /note="Helical"; /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"; TRANSMEM 181..201; /note="Helical"; /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"; TRANSMEM 232..252; /note="Helical"; /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"; TRANSMEM 254..274; /note="Helical"; /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"; TRANSMEM 295..315; /note="Helical"; /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
|
PF00528;
|
IPR000515;IPR035906;IPR011864;IPR051124;
| null |
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype)
|
pstC1 pstC BQ2027_MB0960
| false |
Mycobacterium tuberculosis
| 943 |
row_392457
| false | null |
26,904 |
P9WKJ7
|
MALEMFYDDDADLSIIQGRKVGVIGYGSQGHAHSLSLRDSGVQVRVGLKQGSRSRPKVEEQGLDVDTPAEVAKWADVVMVLAPDTAQAEIFAGDIEPNLKPGDALFFGHGLNVHFGLIKPPADVAVAMVAPKGPGHLVRRQFVDGKGVPCLVAVEQDPRGDGLALALSYAKAIGGTRAGVIKTTFKDETETDLFGEQTVLCGGTEELVKAGFEVMVEAGYPAELAYFEVLHELKLIVDLMYEGGLARMYYSVSDTAEFGGYLSGPRVIDAGTKERMRDILREIQDGSFVHKLVADVEGGNKQLEELRRQNAEHPIEVVGKKLRDLMSWVDRPITETA
|
Ketol-acid reductoisomerase (NADP(+)) (KARI) (EC 1.1.1.86) (Acetohydroxy-acid isomeroreductase) (AHIR) (Alpha-keto-beta-hydroxylacyl reductoisomerase) (Ketol-acid reductoisomerase type 1) (Ketol-acid reductoisomerase type I)
|
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
| 83,332 | 337 | 36,535 |
3D-structure;Amino-acid biosynthesis;Branched-chain amino acid biosynthesis;Direct protein sequencing;Magnesium;Metal-binding;NADP;Oxidoreductase;Reference proteome
|
GO:0000287; GO:0004455; GO:0005829; GO:0005886; GO:0009097; GO:0009099; GO:0050661
|
Evidence at protein level
| 5 | null | null | null |
PF01450;PF07991;
|
IPR008927;IPR013023;IPR000506;IPR013116;IPR014359;IPR036291;
|
4YPO;
|
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
|
ilvC Rv3001c MTV012.15c
| false |
Mycobacterium tuberculosis
| 944 |
row_23545
| false | null |
6,628 |
O53581
|
MAKNSRRKRHRILAWIAAGAMASVVALVIVAVVIMLRGAESPPSAVPPGVLPPGPTPAHPHKPRPAFQDASCPDVQMISVPGTWESSPQQNPLNPVQFPKALLLKVTGPIAQQFAPARVQTYTVAYTAQFHNPLTTDNQMSYNDSRAEGTRAMVAAMTDMNNRCPLTSYVLIGFSQGAVIAGDVASDIGNGRGPVDEDLVLGVTLIADGRRQQGVGNQVPPSPRGEGAEITLHEVPVLSGLGLTMTGPRPGGFGALDGRTNEICAQGDLICAAPAQAFSPANLPTTLNTLAGGAGQPVHAMYATPEFWNSDGEPATEWTLNWAHQLIENAPHPKHR
|
Carboxylesterase/lipase Culp6 (EC 3.1.1.-) (Cell wall lipase) (Cutinase-like protein 6) (Culp6)
|
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
| 83,332 | 336 | 35,448 |
3D-structure;Cell membrane;Cell wall;Disulfide bond;Hydrolase;Membrane;Reference proteome;Secreted;Serine esterase;Transmembrane;Transmembrane helix
|
GO:0005576; GO:0005886; GO:0008970; GO:0009274; GO:0016042; GO:0016298; GO:0047617; GO:0106435
|
Evidence at protein level
| 5 |
SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000255}. Secreted, cell wall {ECO:0000269|PubMed:19225166}.
| null |
TRANSMEM 16..36; /note="Helical"; /evidence="ECO:0000255"
|
PF01083;
|
IPR029058;IPR000675;
|
5W95;
|
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
|
cut6 Rv3802c
| false |
Mycobacterium tuberculosis
| 945 |
row_5462
| false | null |
26,970 |
P9WNE1
|
MAELKLGYKASAEQFAPRELVELAVAAEAHGMDSATVSDHFQPWRHQGGHAPFSLSWMTAVGERTNRLLLGTSVLTPTFRYNPAVIAQAFATMGCLYPNRVFLGVGTGEALNEIATGYEGAWPEFKERFARLRESVGLMRQLWSGDRVDFDGDYYRLKGASIYDVPDGGVPVYIAAGGPAVAKYAGRAGDGFICTSGKGEELYTEKLMPAVREGAAAADRSVDGIDKMIEIKISYDPDPELALNNTRFWAPLSLTAEQKHSIDDPIEMEKAADALPIEQIAKRWIVASDPDEAVEKVGQYVTWGLNHLVFHAPGHDQRRFLELFQSDLAPRLRRLG
|
F420-dependent glucose-6-phosphate dehydrogenase (FGD) (FGD1) (G6PD) (EC 1.1.98.2)
|
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
| 83,332 | 336 | 36,989 |
3D-structure;Carbohydrate metabolism;Oxidoreductase;Reference proteome
|
GO:0005829; GO:0005886; GO:0005975; GO:0009274; GO:0016614; GO:0016705; GO:0045454; GO:0052749; GO:0070967
|
Evidence at protein level
| 5 | null | null | null |
PF00296;
|
IPR019944;IPR050564;IPR019945;IPR011251;IPR036661;
|
3B4Y;3C8N;
|
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
|
fgd1 fgd Rv0407
| false |
Mycobacterium tuberculosis
| 946 |
row_23610
| false | null |
67,938 |
O06334
|
MLMTATHREPIVLDTTVRDGSYAVNFQYTDDDVRRIVGDLDAAGIPYIEIGHGVTIGAAAAQGPAAHTDEEYFRAARSVVRNARLGAVIVPALARIETVDLAGDYLDFLRICVIATEFELVMPFVERAQSKGLEVSIQLVKSHLFEPDVLAAAGKRARDVGVRIVYVVDTTGTFLPEDARRYVEALRGASDVSVGFHGHNNLAMAVANTLEAFDAGADFLDGTLMGFGRGAGNCQIECLVAALQRRGHLAAVDLDRIFDAARSDMLGRSPQSYGIDPWEISFGFHGLDSLQVEHLRAAAQQAGLSVSHVIRQTAKSHAGQWLSPQDIDRVVVGMRA
|
Oxaloacetate decarboxylase (OAA decarboxylase) (EC 4.1.1.112)
|
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
| 83,332 | 336 | 36,297 |
Lyase;Manganese;Metal-binding;Reference proteome
|
GO:0003852; GO:0008948; GO:0009098; GO:0046872
|
Evidence at protein level
| 4 | null | null | null |
PF00682;
|
IPR050073;IPR013785;IPR000891;
| null |
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
|
mhpE Rv3469c
| false |
Mycobacterium tuberculosis
| 947 |
row_59030
| false | null |
81,821 |
P9WKK9
|
MKLAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNHDAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLSGNPGIDFVVVREGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRRRKHLTLVHKTNVLTFAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDIITDLAAAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSHLGEHDAAARVDRAVEAHLATRGSERLATSDVGERIAAAL
|
3-isopropylmalate dehydrogenase (EC 1.1.1.85) (3-IPM-DH) (Beta-IPM dehydrogenase) (IMDH)
|
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
| 83,332 | 336 | 35,306 |
3D-structure;Amino-acid biosynthesis;Branched-chain amino acid biosynthesis;Cytoplasm;Leucine biosynthesis;Magnesium;Manganese;Metal-binding;NAD;Oxidoreductase;Reference proteome
|
GO:0000287; GO:0003862; GO:0005737; GO:0009098; GO:0051287
|
Evidence at protein level
| 4 |
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01035}.
| null | null |
PF00180;
|
IPR050501;IPR019818;IPR024084;IPR023698;
|
1W0D;2G4O;
|
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
|
leuB Rv2995c MTV012.09
| false |
Mycobacterium tuberculosis
| 948 |
row_72267
| false | null |
209,144 |
P71615
|
MTTIDPRSELVDGRRRAGARVDAVGAAALLSAAARVGVVCHVHPDADTIGAGLALALVLDGCGKRVEVSFAAPATLPESLRSLPGCHLLVRPEVMRRDVDLVVTVDIPSVDRLGALGDLTDSGRELLVIDHHASNDLFGTANFIDPSADSTTTMVAEILDAWGKPIDPRVAHCIYAGLATDTGSFRWASVRGYRLAARLVEIGVDNATVSRTLMDSHPFTWLPLLSRVLGSAQLVSEAVGGRGLVYVVVDNREWVAARSEEVESIVDIVRTTQQAEVAAVFKEVEPHRWSVSMRAKTVNLAAVASGFGGGGHRLAAGYTTTGSIDDAVASLRAALG
|
Bifunctional oligoribonuclease and PAP phosphatase NrnA (EC 3.1.-.-) (3'(2'),5'-bisphosphate nucleotidase) (EC 3.1.3.7) (3'-phosphoadenosine 5'-phosphate phosphatase) (PAP phosphatase) (nanoRNase)
|
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
| 83,332 | 336 | 35,415 |
3D-structure;Exonuclease;Hydrolase;Nuclease;Reference proteome
|
GO:0003676; GO:0004527; GO:0008441
|
Evidence at protein level
| 3 | null | null | null |
PF01368;PF02272;
|
IPR001667;IPR038763;IPR003156;IPR051319;
|
5CET;5JJU;
|
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
|
nrnA Rv2837c
| false |
Mycobacterium tuberculosis
| 949 |
row_195544
| false | null |
212,317 |
P9WFT2
|
MSTPTGSRRIFSGVQPTSDSLHLGNALGAVAQWVGLQDDHDAFFCVVDLHAITIPQDPEALRRRTLITAAQYLALGIDPGRATIFVQSQVPAHTQLAWVLGCFTGFGQASRMTQFKDKSARQGSEATTVGLFTYPVLQAADVLAYDTELVPVGEDQRQHLELARDVAQRFNSRFPGTLVVPDVLIPKMTAKIYDLQDPTSKMSKSAGTDAGLINLLDDPALSAKKIRSAVTDSERDIRYDPDVKPGVSNLLNIQSAVTGTDIDVLVDGYAGHGYGDLKKDTAEAVVEFVNPIQARVDELTADPAELEAVLAAGAQRAHDVASKTVQRVYDRLGFLL
|
Tryptophan--tRNA ligase (EC 6.1.1.2) (Tryptophanyl-tRNA synthetase) (TrpRS)
|
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
| 83,331 | 336 | 36,272 |
Aminoacyl-tRNA synthetase;ATP-binding;Cytoplasm;Ligase;Nucleotide-binding;Protein biosynthesis;Reference proteome
|
GO:0004830; GO:0005524; GO:0005829; GO:0006436
|
Inferred from homology
| 3 |
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00140}.
| null | null |
PF00579;
|
IPR001412;IPR002305;IPR014729;IPR002306;IPR024109;IPR050203;
| null |
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
|
trpS MT3440
| false |
Mycobacterium tuberculosis
| 950 |
row_198530
| false | null |
213,161 |
P9WPZ1
|
MAMMAASHDDDTVDGLATAVRGGDRAALPRAITLVESTRPDHREQAQQLLLRLLPDSGNAHRVGITGVPGVGKSTAIEALGMHLIERGHRVAVLAVDPSSTRTGGSILGDKTRMARLAVHPNAYIRPSPTSGTLGGVTRATRETVVLLEAAGFDVILIETVGVGQSEVAVANMVDTFVLLTLARTGDQLQGIKKGVLELADIVVVNKADGEHHKEARLAARELSAAIRLIYPREALWRPPVLTMSAVEGRGLAELWDTVERHRQVLTGAGEFDARRRDQQVDWTWQLVRDAVLDRVWSNPTVRKVRSELERRVRAGELTPALAAQQILEIANLTDR
|
Probable GTPase Rv1496 (EC 3.6.-.-)
|
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
| 83,332 | 336 | 36,459 |
3D-structure;ATP-binding;Chaperone;Direct protein sequencing;GTP-binding;Hydrolase;Nucleotide-binding;Reference proteome
|
GO:0003924; GO:0005524; GO:0005525; GO:0005737
|
Evidence at protein level
| 3 | null | null | null |
PF03308;
|
IPR005129;IPR027417;
|
3MD0;3P32;4GT1;
|
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
|
Rv1496 MTCY277.18
| false |
Mycobacterium tuberculosis
| 951 |
row_199359
| false | null |
4,125 |
I6Y4U9
|
MAVPAVSPQPILAPLTPAAIFLVATIGADGEATVHDALSKISGLVRAIGFRDPTKHLSVVVSIGSDAWDRLFAGPRPTELHPFVELTGPRHTAPATPGDLLFHIRAETMDVCFELAGRILKSMGDAVTVVDEVHGFRFFDNRDLLGFVDGTENPSGPIAIKATTIGDEDRNFAGSCYVHVQKYVHDMASWESLSVTEQERVIGRTKLDDIELDDNAKPANSHVALNVITDDDGTERKIVRHNMPFGEVGKGEYGTYFIGYSRTPTVTEQMLRNMFLGDPAGNTDRVLDFSTAVTGGLFFSPTIDFLDHPPPLPQAATPTLAAGSLSIGSLKGSPR
|
Dye-decolorizing peroxidase (DyP) (EC 1.11.1.7)
|
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
| 83,332 | 335 | 36,048 |
3D-structure;Encapsulin nanocompartment;Heme;Iron;Metal-binding;Oxidoreductase;Peroxidase;Reference proteome;Virulence
|
GO:0004601; GO:0005829; GO:0020037; GO:0046872; GO:0140737
|
Evidence at protein level
| 5 |
SUBCELLULAR LOCATION: Encapsulin nanocompartment {ECO:0000269|PubMed:24855650}. Note=Consistently identified in encapsulin nanocompartments isolated in situ (PubMed:34751132). Located inside the nanocompartment in E.coli (Probable). {ECO:0000269|PubMed:34751132, ECO:0000305|PubMed:24855650}.
| null | null |
PF20628;PF04261;
|
IPR011008;IPR048328;IPR048327;IPR006314;
|
9BKX;
|
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
|
dyp Rv0799c
| false |
Mycobacterium tuberculosis
| 952 |
row_3274
| false | null |
4,620 |
O06428
|
MRTPATVVAGVDLGDAVFAAAVRAGVARVEQLMDTELRQADEVMSDSLLHLFNAGGKRFRPLFTVLSAQIGPQPDAAAVTVAGAVIEMIHLATLYHDDVMDEAQVRRGAPSANAQWGNNVAILAGDYLLATASRLVARLGPEAVRIIADTFAQLVTGQMRETRGTSENVDSIEQYLKVVQEKTGSLIGAAGRLGGMFSGATDEQVERLSRLGGVVGTAFQIADDIIDIDSESDESGKLPGTDVREGVHTLPMLYALRESGPDCARLRALLNGPVDDDAEVREALTLLRASPGMARAKDVLAQYAAQARHELALLPDVPGRRALAALVDYTVSRHG
|
Nonaprenyl diphosphate synthase (EC 2.5.1.85) ((2E,6E)-farnesyl diphosphate synthase) (E,E-FPP synthase) (FPP synthase) (EC 2.5.1.10) (Geranylgeranyl diphosphate synthase) (GGPP synthase) (GGPS) (EC 2.5.1.29)
|
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
| 83,332 | 335 | 35,560 |
Lipid biosynthesis;Lipid metabolism;Magnesium;Metal-binding;Reference proteome;Transferase
|
GO:0004311; GO:0004337; GO:0004659; GO:0005886; GO:0008299; GO:0009274; GO:0033386; GO:0046872; GO:0052924
|
Evidence at protein level
| 5 | null | null | null |
PF00348;
|
IPR008949;IPR053541;IPR000092;IPR033749;
| null |
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
|
grcC1 Rv0562
| false |
Mycobacterium tuberculosis
| 953 |
row_3700
| false | null |
26,782 |
P9WHH1
|
MTAPPVHDRAHHPVRDVIVIGSGPAGYTAALYAARAQLAPLVFEGTSFGGALMTTTDVENYPGFRNGITGPELMDEMREQALRFGADLRMEDVESVSLHGPLKSVVTADGQTHRARAVILAMGAAARYLQVPGEQELLGRGVSSCATCDGFFFRDQDIAVIGGGDSAMEEATFLTRFARSVTLVHRRDEFRASKIMLDRARNNDKIRFLTNHTVVAVDGDTTVTGLRVRDTNTGAETTLPVTGVFVAIGHEPRSGLVREAIDVDPDGYVLVQGRTTSTSLPGVFAAGDLVDRTYRQAVTAAGSGCAAAIDAERWLAEHAATGEADSTDALIGAQR
|
Thioredoxin reductase (TR) (TRXR) (EC 1.8.1.9)
|
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
| 83,332 | 335 | 35,643 |
3D-structure;Acetylation;Cytoplasm;Disulfide bond;FAD;Flavoprotein;NADP;Oxidoreductase;Phosphoprotein;Redox-active center;Reference proteome
|
GO:0001666; GO:0004791; GO:0005829; GO:0015035; GO:0019430; GO:0045454; GO:0050660; GO:0070402
|
Evidence at protein level
| 5 |
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
| null | null |
PF07992;
|
IPR036188;IPR023753;IPR050097;IPR008255;IPR005982;
|
2A87;
|
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
|
trxB trxB2 trxR Rv3913 MTV028.04
| false |
Mycobacterium tuberculosis
| 954 |
row_23428
| false | null |
26,973 |
P9WNG3
|
MTEIATTSGARSVGLLSVGAYRPERVVTNDEICQHIDSSDEWIYTRTGIKTRRFAADDESAASMATEACRRALSNAGLSAADIDGVIVTTNTHFLQTPPAAPMVAASLGAKGILGFDLSAGCAGFGYALGAAADMIRGGGAATMLVVGTEKLSPTIDMYDRGNCFIFADGAAAVVVGETPFQGIGPTVAGSDGEQADAIRQDIDWITFAQNPSGPRPFVRLEGPAVFRWAAFKMGDVGRRAMDAAGVRPDQIDVFVPHQANSRINELLVKNLQLRPDAVVANDIEHTGNTSAASIPLAMAELLTTGAAKPGDLALLIGYGAGLSYAAQVVRMPKG
|
Mycobacterial beta-ketoacyl-[acyl-carrier-protein] synthase III (Beta-ketoacyl-ACP synthase III) (KAS III) (EC 2.3.1.301) (3-oxoacyl-[acyl-carrier-protein] synthase 3) (3-oxoacyl-[acyl-carrier-protein] synthase III) (MtFabH)
|
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
| 83,332 | 335 | 34,873 |
3D-structure;Acetylation;Acyltransferase;Cytoplasm;Fatty acid biosynthesis;Fatty acid metabolism;Lipid biosynthesis;Lipid metabolism;Multifunctional enzyme;Phosphoprotein;Reference proteome;Transferase
|
GO:0000062; GO:0004315; GO:0005737; GO:0006633; GO:0008610; GO:0030497; GO:0033818; GO:0035336; GO:0061990
|
Evidence at protein level
| 5 |
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01815}.
| null | null |
PF08545;PF08541;
|
IPR013747;IPR013751;IPR004655;IPR016039;
|
1HZP;1M1M;1U6E;1U6S;2AHB;2AJ9;2QNX;2QNY;2QNZ;2QO0;2QO1;2QX1;
|
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
|
fabH Rv0533c MTCY25D10.12c
| false |
Mycobacterium tuberculosis
| 955 |
row_23613
| false | null |
81,812 |
P9WKG1
|
MVPTVDMGIPGASVSSRSVADRPNRKRVLLAEPRGYCAGVDRAVETVERALQKHGPPVYVRHEIVHNRHVVDTLAKAGAVFVEETEQVPEGAIVVFSAHGVAPTVHVSASERNLQVIDATCPLVTKVHNEARRFARDDYDILLIGHEGHEEVVGTAGEAPDHVQLVDGVDAVDQVTVRDEDKVVWLSQTTLSVDETMEIVGRLRRRFPKLQDPPSDDICYATQNRQVAVKAMAPECELVIVVGSRNSSNSVRLVEVALGAGARAAHLVDWADDIDSAWLDGVTTVGVTSGASVPEVLVRGVLERLAECGYDIVQPVTTANETLVFALPRELRSPR
|
4-hydroxy-3-methylbut-2-enyl diphosphate reductase 2 (HDR 2) (HMBPP reductase 2) (EC 1.17.7.4)
|
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
| 83,332 | 335 | 36,297 |
4Fe-4S;Iron;Iron-sulfur;Isoprene biosynthesis;Metal-binding;Oxidoreductase;Reference proteome
|
GO:0005829; GO:0016114; GO:0019288; GO:0046872; GO:0050992; GO:0051539; GO:0051745
|
Evidence at protein level
| 4 | null | null | null |
PF02401;
|
IPR003451;
| null |
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
|
ispH2 lytB2 Rv1110 MTV017.63
| false |
Mycobacterium tuberculosis
| 956 |
row_72258
| false | null |
431,094 |
P9WFJ6
|
MTLPLLGPMTLSGFAHSWFFLFLFVVAGLVALYILMQLARQRRMLRFANMELLESVAPKRPSRWRHVPAILLVLSLLLFTIAMAGPTHDVRIPRNRAVVMLVIDVSQSMRATDVEPSRMVAAQEAAKQFADELTPGINLGLIAYAGTATVLVSPTTNREATKNALDKLQFADRTATGEAIFTALQAIATVGAVIGGGDTPPPARIVLFSDGKETMPTNPDNPKGAYTAARTAKDQGVPISTISFGTPYGFVEINDQRQPVPVDDETMKKVAQLSGGNSYNAATLAELRAVYSSLQQQIGYETIKGDASVGWLRLGALALALAALAALLINRRLPT
|
UPF0353 protein MT1528
|
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
| 83,331 | 335 | 36,030 |
Cell membrane;Membrane;Reference proteome;Transmembrane;Transmembrane helix
|
GO:0005886
|
Inferred from homology
| 2 |
SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01340}; Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01340}.
| null |
TRANSMEM 18..38; /note="Helical"; /evidence="ECO:0000255|HAMAP-Rule:MF_01340"; TRANSMEM 67..87; /note="Helical"; /evidence="ECO:0000255|HAMAP-Rule:MF_01340"; TRANSMEM 309..329; /note="Helical"; /evidence="ECO:0000255|HAMAP-Rule:MF_01340"
|
PF07584;PF13519;
|
IPR024163;IPR022933;IPR050768;IPR002035;IPR036465;
| null |
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
|
MT1528
| false |
Mycobacterium tuberculosis
| 957 |
row_412853
| false | null |
81,862 |
P9WN77
|
MAGIASTVAVMGAGAWGTALAKVLADAGGEVTLWARRAEVADQINTTRYNPDYLPGALLPPSIHATADAEEALGGASTVLLGVPAQTMRANLERWAPLLPEGATLVSLAKGIELGTLMRMSQVIISVTGAEPPQVAVISGPNLASEIAECQPAATVVACSDSGRAVALQRALNSGYFRPYTNADVVGTEIGGACKNIIALACGMAVGIGLGENTAAAIITRGLAEIIRLGTALGANGATLAGLAGVGDLVATCTSPRSRNRSFGERLGRGETLQSAGKACHVVEGVTSCESVLALASSYDVEMPLTDAVHRVCHKGLSVDEAITLLLGRRTKPE
|
Glycerol-3-phosphate dehydrogenase [NAD(P)+] 2 (EC 1.1.1.94) (NAD(P)(+)-dependent glycerol-3-phosphate dehydrogenase 2) (NAD(P)H-dependent dihydroxyacetone-phosphate reductase 2)
|
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
| 83,332 | 334 | 33,992 |
Cytoplasm;Lipid biosynthesis;Lipid metabolism;NAD;NADP;Nucleotide-binding;Oxidoreductase;Phospholipid biosynthesis;Phospholipid metabolism;Reference proteome
|
GO:0005829; GO:0005886; GO:0005975; GO:0006072; GO:0006650; GO:0008654; GO:0046167; GO:0046168; GO:0047952; GO:0051287
|
Evidence at protein level
| 4 |
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00394}.
| null | null |
PF07479;PF01210;
|
IPR008927;IPR013328;IPR006168;IPR006109;IPR011128;IPR036291;
| null |
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
|
gpsA2 gpdA2 Rv2982c MTCY349.05
| false |
Mycobacterium tuberculosis
| 958 |
row_72306
| false | null |
4,614 |
O05581
|
MDGIAELTGARVEDLAGMDVFQGCPAEGLVSLAASVQPLRAAAGQVLLRQGEPAVSFLLISSGSAEVSHVGDDGVAIIARALPGMIVGEIALLRDSPRSATVTTIEPLTGWTGGRGAFATMVHIPGVGERLLRTARQRLAAFVSPIPVRLADGTQLMLRPVLPGDRERTVHGHIQFSGETLYRRFMSARVPSPALMHYLSEVDYVDHFVWVVTDGSDPVADARFVRDETDPTVAEIAFTVADAYQGRGIGSFLIGALSVAARVDGVERFAARMLSDNVPMRTIMDRYGAVWQREDVGVITTMIDVPGPGELSLGREMVDQINRVARQVIEAVG
|
Acetyltransferase Pat (EC 2.3.1.-) (GCN5-like enzyme) (GCN5-related N-acetyltransferase) (GNAT) (Protein acetyltransferase) (Pat)
|
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
| 83,332 | 333 | 35,626 |
3D-structure;Acyltransferase;Magnesium;Metal-binding;Reference proteome;Transferase
|
GO:0003700; GO:0005829; GO:0016407; GO:0016746; GO:0030552; GO:0046872
|
Evidence at protein level
| 5 | null | null | null |
PF13302;PF00027;
|
IPR016181;IPR018488;IPR000595;IPR018490;IPR050397;IPR000182;IPR014710;
|
4AVA;4AVB;4AVC;
|
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
|
Rv0998
| false |
Mycobacterium tuberculosis
| 959 |
row_3694
| false | null |
431,175 |
P9WG70
|
MTTKDHSLATESPTLQQLGEFAVIDRLVRGRRQPATVLLGPGDDAALVSAGDGRTVVSTDMLVQDSHFRLDWSTPQDVGRKAIAQNAADIEAMGARATAFVVGFGAPAETPAAQASALVDGMWEEAGRIGAGIVGGDLVSCRQWVVSVTAIGDLDGRAPVLRSGAKAGSVLAVVGELGRSAAGYALWCNGIEDFAELRRRHLVPQPPYGHGAAAAAVGAQAMIDVSDGLLADLRHIAEASGVRIDLSAAALAADRDALTAAATALGTDPWPWVLSGGEDHALVACFVGPVPAGWRTIGRVLDGPARVLVDGEEWTGYAGWQSFGEPDNQGSLG
|
Thiamine-monophosphate kinase (TMP kinase) (Thiamine-phosphate kinase) (EC 2.7.4.16)
|
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
| 83,331 | 333 | 34,331 |
ATP-binding;Kinase;Magnesium;Metal-binding;Nucleotide-binding;Reference proteome;Thiamine biosynthesis;Transferase
|
GO:0000287; GO:0005524; GO:0009030; GO:0009228; GO:0009229
|
Inferred from homology
| 2 | null | null | null |
PF00586;PF02769;
|
IPR010918;IPR036676;IPR016188;IPR036921;IPR006283;
| null |
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
|
thiL MT3055
| false |
Mycobacterium tuberculosis
| 960 |
row_412934
| false | null |
212,622 |
P9WIM1
|
MATSKVERLVNLVIALLSTRGYITAEKIRSSVAGYSDSPSVEAFSRMFERDKNELRDLGIPLEVGRVSALEPTEGYRINRDAYALSPVELTPDEAAAVAVATQLWESPELITATQGALLKLRAAGVDVDPLDTGAPVAIASAAAVSGLRGSEDVLGILLSAIDSGQVVQFSHRSSRAEPYTVRTVEPWGVVTEKGRWYLVGHDRDRDATRVFRLSRIGAQVTPIGPAGATTVPAGVDLRSIVAQKVTEVPTGEQATVWVAEGRATALRRAGRSAGPRQLGGRDGEVIELEIRSSDRLAREITGYGADAIVLQPGSLRDDVLARLRAQAGALA
|
Protein PafB (Proteasome accessory factor B)
|
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
| 83,332 | 332 | 35,300 |
Reference proteome
|
GO:0005886; GO:0009274
|
Evidence at protein level
| 3 | null | null | null |
PF13280;
|
IPR051534;IPR026881;
| null |
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
|
pafB Rv2096c MTCY49.36c
| false |
Mycobacterium tuberculosis
| 961 |
row_198830
| false | null |
431,205 |
P9WGF4
|
MTHDHAHSRGVPAMIKEIFAPHSHDAADSVDDTLESTAAGIRTVKISLLVLGLTALIQIVIVVMSGSVALAADTIHNFADALTAVPLWIAFALGAKPATRRYTYGFGRVEDLAGSFVVAMITMSAIIAGYEAIARLIHPQQIEHVGWVALAGLVGFIGNEWVALYRIRVGHRIGSAALIADGLHARTDGFTSLAVLCSAGGVALGFPLADPIVGLLITAAILAVLRTAARDVFRRLLDGVDPAMVDAAEQALAARPGVQAVRSVRMRWIGHRLHADAELDVDPALDLAQAHRIAHDAEHELTHTVPKLTTALIHAYPAEHGSSIPDRGRTVE
|
Probable cation efflux system protein MT2084
|
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
| 83,331 | 332 | 35,207 |
Cell membrane;Ion transport;Membrane;Reference proteome;Transmembrane;Transmembrane helix;Transport
|
GO:0005886; GO:0006882; GO:0015086; GO:0015093; GO:0015341
|
Inferred from homology
| 2 |
SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
| null |
TRANSMEM 46..66; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 75..95; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 113..133; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 145..165; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 202..222; /note="Helical"; /evidence="ECO:0000255"
|
PF01545;PF16916;
|
IPR002524;IPR027470;IPR036837;IPR027469;IPR050291;
| null |
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
|
MT2084
| false |
Mycobacterium tuberculosis
| 962 |
row_412964
| false | null |
27,085 |
P9WQL9
|
MRNDDMAVVVNGVRKTYGKGKIVALDDVSFKVRRGEVIGLLGPNGAGKTTMVDILSTLTRPDAGSAIIAGYDVVSEPAGVRRSIMVTGQQVAVDDALSGEQNLVLFGRLWGLSKSAARKRAAELLEQFSLVHAGKRRVGTYSGGMRRRIDIACGLVVQPQVAFLDEPTTGLDPRSRQAIWDLVASFKKLGIATLLTTQYLEEADALSDRIILIDHGIIIAEGTANELKHRAGDTFCEIVPRDLKDLDAIVAALGSLLPEHHRAMLTPDSDRITMPAPDGIRMLVEAARRIDEARIELADIALRRPSLDHVFLAMTTDPTESLTHLVSGSAR
|
Doxorubicin resistance ATP-binding protein DrrA (EC 7.6.2.-)
|
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
| 83,332 | 331 | 35,818 |
Antibiotic resistance;ATP-binding;Cell membrane;Membrane;Nucleotide-binding;Reference proteome;Translocase;Transport
|
GO:0005524; GO:0005886; GO:0006869; GO:0009274; GO:0016887; GO:0043215; GO:0046677; GO:0051701; GO:0055085; GO:1900753
|
Evidence at protein level
| 5 |
SUBCELLULAR LOCATION: Cell membrane {ECO:0000305|PubMed:12057006}; Peripheral membrane protein {ECO:0000305|PubMed:12057006}; Cytoplasmic side {ECO:0000305|PubMed:12057006}.
| null | null |
PF00005;
|
IPR003593;IPR003439;IPR017871;IPR050763;IPR005894;IPR027417;
| null |
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
|
drrA Rv2936
| false |
Mycobacterium tuberculosis
| 963 |
row_23718
| false | null |
81,860 |
P9WN65
|
MRLLVTGGAGFIGTNFVHSAVREHPDDAVTVLDALTYAGRRESLADVEDAIRLVQGDITDAELVSQLVAESDAVVHFAAESHVDNALDNPEPFLHTNVIGTFTILEAVRRHGVRLHHISTDEVYGDLELDDRARFTESTPYNPSSPYSATKAGADMLVRAWVRSYGVRATISNCSNNYGPYQHVEKFIPRQITNVLTGRRPKLYGAGANVRDWIHVDDHNSAVRRILDRGRIGRTYLISSEGERDNLTVLRTLLRLMDRDPDDFDHVTDRVGHDLRYAIDPSTLYDELCWAPKHTDFEEGLRTTIDWYRDNESWWRPLKDATEARYQERGQ
|
dTDP-glucose 4,6-dehydratase (EC 4.2.1.46)
|
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
| 83,332 | 331 | 37,558 |
Lyase;NAD;Reference proteome
|
GO:0000271; GO:0008460; GO:0009274; GO:0019305; GO:0070404
|
Evidence at protein level
| 4 | null | null | null |
PF16363;
|
IPR005888;IPR016040;IPR036291;
| null |
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
|
rmlB rfbB Rv3464
| false |
Mycobacterium tuberculosis
| 964 |
row_72304
| false | null |
212,676 |
P9WJE5
|
MNPIPSWPGRGRVTLVLLAVVPVALAYPWQSTRDYVLLGVAAAVVIGLFGFWRGLYFTTIARRGLAILRRRRRIAEPATCTRTTVLVWVGPPASDTNVLPLTLIARYLDRYGIRADTIRITSRVTASGDCRTWVGLTVVADDNLAALQARSARIPLQETAQVAARRLADHLREIGWEAGTAAPDEIPALVAADSRETWRGMRHTDSDYVAAYRVSANAELPDTLPAIRSRPAQETWIALEIAYAAGSSTRYTVAAACALRTDWRPGGTAPVAGLLPQHGNHVPALTALDPRSTRRLDGHTDAPADLLTRLHWPTPTAGAHRAPLTNAVSRT
|
ESX-3 secretion system protein EccE3 (ESX conserved component E3) (Type VII secretion system protein EccE3) (T7SS protein EccE3)
|
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
| 83,332 | 331 | 35,932 |
Cell inner membrane;Cell membrane;Membrane;Reference proteome;Transmembrane;Transmembrane helix;Transport
|
GO:0005886; GO:0009274
|
Evidence at protein level
| 3 |
SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250|UniProtKB:B2HSU8}; Multi-pass membrane protein {ECO:0000255}.
| null |
TRANSMEM 11..31; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 37..57; /note="Helical"; /evidence="ECO:0000255"
|
PF11203;
|
IPR050051;IPR021368;
| null |
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
|
eccE3 Rv0292
| false |
Mycobacterium tuberculosis
| 965 |
row_198883
| false | null |
213,070 |
P9WP81
|
MKVTVLAGGVGGARFLLGVQQLLGLGQFAANSAHSDADHQLSAVVNVGDDAWIHGLRVCPDLDTCMYTLGGGVDPQRGWGQRDETWHAMQELVRYGVQPDWFELGDRDLATHLVRTQMLQAGYPLSQITEALCDRWQPGARLLPATDDRCETHVVITDPVDESRKAIHFQEWWVRYRAQVPTHSFAFVGAEKSSAATEAIAALADADIIMLAPSNPVVSIGAILAVPGIRAALREATAPIVGYSPIIGEKPLRGMADTCLSVIGVDSTAAAVGRHYGARCATGILDCWLVHDGDHAEIDGVTVRSVPLLMTDPNATAEMVRAGCDLAGVVA
|
Phosphoenolpyruvate transferase (EC 2.7.8.28) (EPPG:FO PEP transferase)
|
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
| 83,332 | 331 | 35,335 |
Magnesium;Reference proteome;Transferase
|
GO:0000287; GO:0043743; GO:0052645; GO:2001121
|
Evidence at protein level
| 3 | null | null | null |
PF01933;
|
IPR002882;IPR038136;IPR010115;
| null |
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
|
fbiA Rv3261
| false |
Mycobacterium tuberculosis
| 966 |
row_199270
| false | null |
276,534 |
Q79FU2
|
MSFVNVAPQLVSTAAADAARIGSAINTANTAAAATTQVLAAAQDEVSTAIAALFGSHGQHYQAISAQVAAYQQRFVLALSQAGSTYAVAEAASATPLQNVLDAINAPVQSLTGRPLIGDGANGIDGTGQAGGNGGWLWGNGGNGGSGAPGQAGGAGGAAGLIGNGGAGGTGGAVSLARAGTAGGAGRGPVGGIGGAGGVGGAGGAAGAVTTITHASFNDPHGVAVNPGGNVYVTNFGSGTVSVINPATNTVTGSPITIGNGPSGVAVSPVTGLVFVTNFDSNTVSVIDPTTNTVTGSPITVGTAPTGVAVNPVTGEVYVTNFAGDTVSVIS
|
PE-PGRS family protein PE_PGRS17
|
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
| 83,332 | 331 | 31,019 |
Reference proteome;Repeat;Virulence
| null |
Evidence at protein level
| 3 | null | null | null |
PF01436;PF00934;PF21526;
|
IPR051200;IPR001258;IPR000084;IPR048996;IPR015943;IPR011964;
| null |
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
|
PE_PGRS17 Rv0978c
| false |
Mycobacterium tuberculosis
| 967 |
row_260930
| false | null |
431,581 |
P9WIZ8
|
MPDTMVTTDVIKSAVQLACRAPSLHNSQPWRWIAEDHTVALFLDKDRVLYATDHSGREALLGCGAVLDHFRVAMAAAGTTANVERFPNPNDPLHLASIDFSPADFVTEGHRLRADAILLRRTDRLPFAEPPDWDLVESQLRTTVTADTVRIDVIADDMRPELAAASKLTESLRLYDSSYHAELFWWTGAFETSEGIPHSSLVSAAESDRVTFGRDFPVVANTDRRPEFGHDRSKVLVLSTYDNERASLLRCGEMLSAVLLDATMAGLATCTLTHITELHASRDLVAALIGQPATPQALVRVGLAPEMEEPPPATPRRPIDEVFHVRAKDHR
|
Putative NAD(P)H nitroreductase acg (EC 1.-.-.-)
|
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
| 83,331 | 331 | 36,559 |
Flavoprotein;FMN;NAD;NADP;Oxidoreductase;Reference proteome
|
GO:0016491
|
Inferred from homology
| 2 | null | null | null | null |
IPR000415;IPR050627;
| null |
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
|
acg MT2091
| false |
Mycobacterium tuberculosis
| 968 |
row_413339
| false | null |
213,235 |
P9WQK5
|
MGDLSIQNLVVEYYSGGYALRPINGLNLDVAAGSLVMLLGPSGCGKTTLLSCLGGILRPKSGAIKFDEVDITTLQGAELANYRRNKVGIVFQAFNLVPSLTAVENVMVPLRSAGMSRRASRRRAEELLARVNLAERMNHRPGDLSGGQQQRVAVARAIALDPPLILADEPTAHLDFIQVEEVLRLIRELADGERVVVVATHDSRMLPMADRVVELTPDFAETNRPPETVHLQAGEVLFEQSTMGDLIYVVSEGEFEIVHELADGGEELVKVAGPGDYFGEIGVLFHLPRSATVRARSDATAVGYTVQAFRERLGVGGLRDLIEHRALAND
|
Uncharacterized ABC transporter ATP-binding protein Rv0073
|
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
| 83,332 | 330 | 35,801 |
ATP-binding;Isopeptide bond;Nucleotide-binding;Reference proteome;Transport;Ubl conjugation
|
GO:0005524; GO:0005886; GO:0016887; GO:0022857; GO:0055085
|
Evidence at protein level
| 3 | null | null | null |
PF00005;PF00027;
|
IPR003593;IPR003439;IPR017871;IPR015854;IPR018488;IPR000595;IPR018490;IPR017911;IPR027417;IPR014710;
| null |
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
|
Rv0073
| false |
Mycobacterium tuberculosis
| 969 |
row_199433
| false | null |
425,322 |
P63402
|
MGGLTISDLVVEYSSGGYAVRPIDGLSLDVAPGSLVILLGPSGCGKTTLLSCLGGILRPKSGSIKFDDVDITTLEGAALAKYRRDKVGIVFQAFNLVSSLTALENVMVPLRAAGVSRAAARKRAEDLLIRVNLGERMKHRPGDMSGGQQQRVAVARAIALDPQLILADEPTAHLDFIQVEEVLRLIRSLAQGDRVVVVATHDSRMLPLADRVLELMPAQVSPNQPPETVHVKAGEVLFEQSTMGDLIYVVSEGEFEIVRELADGGEELVKTAAPGDYFGEIGVLFHLPRSATVRARSDATAVGYTAQAFRERLGVTRVADLIEHRELASE
|
Uncharacterized ABC transporter ATP-binding protein Mb2593
|
Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
| 233,413 | 330 | 35,429 |
ATP-binding;Nucleotide-binding;Reference proteome;Transport
|
GO:0005524; GO:0005886; GO:0016887; GO:0022857
|
Inferred from homology
| 2 | null | null | null |
PF00005;PF00027;
|
IPR003593;IPR003439;IPR017871;IPR015854;IPR018488;IPR000595;IPR018490;IPR017911;IPR027417;IPR014710;
| null |
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype)
|
BQ2027_MB2593
| false |
Mycobacterium tuberculosis
| 970 |
row_407423
| false | null |
81,794 |
P9WK13
|
MSASPLKVAVTGAAGQIGYSLLFRLASGSLLGPDRPIELRLLEIEPALQALEGVVMELDDCAFPLLSGVEIGSDPQKIFDGVSLALLVGARPRGAGMERSDLLEANGAIFTAQGKALNAVAADDVRVGVTGNPANTNALIAMTNAPDIPRERFSALTRLDHNRAISQLAAKTGAAVTDIKKMTIWGNHSATQYPDLFHAEVAGKNAAEVVNDQAWIEDEFIPTVAKRGAAIIDARGASSAASAASATIDAARDWLLGTPADDWVSMAVVSDGSYGVPEGLISSFPVTTKGGNWTIVSGLEIDEFSRGRIDKSTAELADERSAVTELGLI
|
Malate dehydrogenase (EC 1.1.1.37)
|
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
| 83,332 | 329 | 34,322 |
3D-structure;NAD;Oxidoreductase;Reference proteome;Tricarboxylic acid cycle
|
GO:0005829; GO:0005886; GO:0005975; GO:0006099; GO:0006107; GO:0006108; GO:0006734; GO:0009274; GO:0030060
|
Evidence at protein level
| 4 | null | null | null |
PF02866;PF00056;
|
IPR001557;IPR022383;IPR001236;IPR015955;IPR001252;IPR010945;IPR036291;
|
4TVO;5KVV;
|
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
|
mdh Rv1240 MTV006.12
| false |
Mycobacterium tuberculosis
| 971 |
row_72240
| false | null |
81,811 |
P9WKF9
|
MAEVFVGPVAQGYASGEVTVLLASPRSFCAGVERAIETVKRVLDVAEGPVYVRKQIVHNTVVVAELRDRGAVFVEDLDEIPDPPPPGAVVVFSAHGVSPAVRAGADERGLQVVDATCPLVAKVHAEAARFAARGDTVVFIGHAGHEETEGTLGVAPRSTLLVQTPADVAALNLPEGTQLSYLTQTTLALDETADVIDALRARFPTLGQPPSEDICYATTNRQRALQSMVGECDVVLVIGSCNSSNSRRLVELAQRSGTPAYLIDGPDDIEPEWLSSVSTIGVTAGASAPPRLVGQVIDALRGYASITVVERSIATETVRFGLPKQVRAQ
|
4-hydroxy-3-methylbut-2-enyl diphosphate reductase 1 (HDR 1) (HMBPP reductase 1) (EC 1.17.7.4)
|
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
| 83,332 | 329 | 34,666 |
4Fe-4S;Iron;Iron-sulfur;Isoprene biosynthesis;Metal-binding;Oxidoreductase;Reference proteome
|
GO:0005829; GO:0016114; GO:0019288; GO:0046872; GO:0050992; GO:0051539; GO:0051745
|
Evidence at protein level
| 4 | null | null | null |
PF02401;
|
IPR003451;
| null |
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
|
ispH1 lytB1 Rv3382c MTV004.40c
| false |
Mycobacterium tuberculosis
| 972 |
row_72257
| false | null |
212,874 |
P9WMP4
|
MSMSSYPRQRPRRLRSTVAMRRLVAQTSLEPRHLVLPMFVADGIDEPRPITSMPGVVQHTRDSLRRAAAAAVAAGVGGLMLFGVPRDQDKDGVGSAGIDPDGILNVALRDLAKDLGEATVLMADTCLDEFTDHGHCGVLDDRGRVDNDATVARYVELAVAQAESGAHVVGPSGMMDGQVAAIRDGLDAAGYIDVVILAYAAKFASAFYGPFREAVSSSLSGDRRTYQQEPGNAAEALREIELDLDEGADIVMVKPAMGYLDVVAAAADVSPVPVAAYQVSGEYAMIRAAAANNWIDERAAVLESLTGIRRAGADIVLTYWAVDAAGWLT
|
Delta-aminolevulinic acid dehydratase (ALAD) (ALADH) (EC 4.2.1.24) (Porphobilinogen synthase)
|
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
| 83,331 | 329 | 34,871 |
Heme biosynthesis;Lyase;Magnesium;Metal-binding;Porphyrin biosynthesis;Reference proteome
|
GO:0004655; GO:0005829; GO:0006782; GO:0008270
|
Inferred from homology
| 3 | null | null | null |
PF00490;
|
IPR001731;IPR030656;IPR013785;
| null |
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
|
hemB MT0533
| false |
Mycobacterium tuberculosis
| 973 |
row_199078
| false | null |
546,708 |
P9WKU6
|
MGESTTQPAGGAAVDDETRSAALPRWRGAAGRLEVWYATLSDPLTRTGLWVHCETVAPTTGGPYAHGWVTWFPPDAPPGTERFGPQPAQPAAGPAWFDIAGVRMAPAELTGRTRSLAWELSWKDTAAPLWTFPRVAWERELLPGAQVVIAPTAVFAGSLAVGETTHRVDSWRGSVAHIYGHGNAKRWGWIHADLGDGDVLEVVTAVSHKPGLRRLAPLAFVRFRIDGKDWPASPLPSLRMRTTLGVRHWQLEGRIGGREALIRVDQPPERCVSLGYTDPDGAKAVCTNTEQADIHIELGGRHWSVLGTGHAEVGLRGTAAPAIKEGTPA
|
Uncharacterized protein MT0513
|
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
| 83,331 | 329 | 35,427 |
Reference proteome
| null |
Predicted
| 1 | null | null | null | null | null | null |
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
|
MT0513
| false |
Mycobacterium tuberculosis
| 974 |
row_526800
| false | null |
81,912 |
P9WPF7
|
MSWLNTKKASCWRSSGRSATKSVTTNDAGTGNPAEQPARGAKQQPATETSRAGRDLRAAIVVGLSIGLVLIAVLVFVPRVWVAIVAVATLVATHEVVRRLREAGYLIPVIPLLIGGQAAVWLTWPFGAVGALAGFGGMVVVCMIWRLFMQDSVTRPTTGGAPSPGNYLSDVSATVFLAVWVPLFCSFGAMLVYPENGSGWVFCMMIAVIASDVGGYAVGVLFGKHPMVPTISPKKSWEGFAGSLVCGITATIITATFLVGKTPWIGALLGVLFVLTTALGDLVESQVKRDLGIKDMGRLLPGHGGLMDRLDGILPSAVAAWIVLTLLP
|
Phosphatidate cytidylyltransferase (EC 2.7.7.41) (CDP-DAG synthase) (CDP-DG synthase) (CDP-diacylglycerol synthase) (CDS) (CDP-diglyceride pyrophosphorylase) (CDP-diglyceride synthase) (CTP:phosphatidate cytidylyltransferase)
|
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
| 83,332 | 328 | 34,458 |
Acetylation;Alternative initiation;Cell membrane;Direct protein sequencing;Lipid biosynthesis;Lipid metabolism;Membrane;Nucleotidyltransferase;Phospholipid biosynthesis;Phospholipid metabolism;Reference proteome;Transferase;Transmembrane;Transmembrane helix
|
GO:0004605; GO:0005886; GO:0009274; GO:0016024
|
Evidence at protein level
| 4 |
SUBCELLULAR LOCATION: Cell membrane {ECO:0000255}; Multi-pass membrane protein {ECO:0000255}.
| null |
TRANSMEM 58..78; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 81..97; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 103..123; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 124..144; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 173..193; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 202..222; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 239..259; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 263..283; /note="Helical"; /evidence="ECO:0000255"
|
PF01148;
|
IPR000374;
| null |
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
|
cdsA Rv2881c MTCY274.12c
| false |
Mycobacterium tuberculosis
| 975 |
row_72352
| false | null |
212,270 |
P9WF45
|
MAMTTDVKDELSRLVVKSVSARRAEVTSLLRFAGGLHIVGGRVVVEAELDLGSIARRLRKEIFELYGYTAVVHVLSASGIRKSTRYVLRVANDGEALARQTGLLDMRGRPVRGLPAQVVGGSIDDAEAAWRGAFLAHGSLTEPGRSSALEVSCPGPEAALALVGAARRLGVGAKAREVRGADRVVVRDGEAIGALLTRMGAQDTRLVWEERRLRREVRATANRLANFDDANLRRSARAAVAAAARVERALEILGDTVPEHLASAGKLRVEHRQASLEELGRLADPPMTKDAVAGRIRRLLSMADRKAKVDGIPDTESVVTPDLLEDA
|
Probable cell division protein WhiA
|
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
| 83,332 | 327 | 35,135 |
Cell cycle;Cell division;Direct protein sequencing;DNA-binding;Reference proteome
|
GO:0003677; GO:0005886; GO:0009274; GO:0043937; GO:0051301
|
Evidence at protein level
| 3 | null | null | null |
PF02650;PF14527;PF10298;
|
IPR027434;IPR018478;IPR003802;IPR023054;IPR039518;
| null |
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
|
whiA Rv1423
| false |
Mycobacterium tuberculosis
| 976 |
row_198483
| false | null |
321,070 |
A1KIG2
|
MNSEHPMTDRVVYRSLMADNLRWDALQLRDGDIIISAPSKSGLTWTQRLVSLLVFDGPDLPGPLSTVSPWLDQTIRPIEEVVATLDAQQHRRFIKTHTPLDGLVLDDRVSYICVGRDPRDAAVSMLYQSANMNEDRMRILHEAVVPFHERIAPPPFAELGHARSPTEEFRDWMEGPNQPPPGIGFTHLKGIGTLANILHQLGTVWVRRHLPNVALFHYADYQADLAGELLRLARVLGIAATRDRARDLAQYATLDAMRSRASEIAPNTTDGIWHSDERFFRRGGSGDWQQFFTEAEHLRYYHRINQLAPPDLLAWAHEGRRGYDPAN
|
Glycolipid sulfotransferase BCG_1434 (EC 2.8.2.-)
|
Mycobacterium bovis (strain BCG / Pasteur 1173P2)
| 410,289 | 327 | 37,119 |
Transferase
|
GO:0008146
|
Inferred from homology
| 2 | null | null | null |
PF00685;
|
IPR027417;IPR000863;
| null |
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype), Mycobacterium tuberculosis variant bovis BCG (no rank)
|
BCG_1434
| false |
Mycobacterium tuberculosis
| 977 |
row_304442
| false | null |
26,847 |
P9WIU5
|
MASKAGLGQTPATTDARRTQKFYRGSPGRPWLIGAVVIPLLIAAIGYGAFERPQSVTGPTGVLPTLTPTSTRGASALSLSLLSISRSGNTVTLIGDFPDEAAKAALMTALNGLLAPGVNVIDQIHVDPVVRSLDFSSAEPVFTASVPIPDFGLKVERDTVTLTGTAPSSEHKDAVKRAATSTWPDMKIVNNIEVTGQAPPGPPASGPCADLQSAINAVTGGPIAFGNDGASLIPADYEILNRVADKLKACPDARVTINGYTDNTGSEGINIPLSAQRAKIVADYLVARGVAGDHIATVGLGSVNPIASNATPEGRAKNRRVEIVVN
|
Peptidoglycan-binding protein ArfA (Outer membrane porin A) (Outer membrane protein A) (OmpATb) (Outer membrane protein ArfA)
|
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
| 83,332 | 326 | 33,574 |
3D-structure;Cell outer membrane;Cell wall;Disulfide bond;Ion transport;Membrane;Metal-binding;Reference proteome;Secreted;Transmembrane;Transmembrane helix;Transport;Zinc
|
GO:0005576; GO:0005829; GO:0005886; GO:0006811; GO:0009274; GO:0009279; GO:0010447; GO:0015288; GO:0042834; GO:0046872; GO:0072488; GO:0075293
|
Evidence at protein level
| 5 |
SUBCELLULAR LOCATION: Secreted, cell wall. Cell outer membrane. Note=Does not have a cleavable signal sequence.
| null |
TRANSMEM 30..50; /note="Helical"; /evidence="ECO:0000255"
|
PF04972;PF21923;PF00691;
|
IPR054121;IPR050330;IPR007055;IPR006664;IPR006665;IPR006690;IPR036737;
|
2KGS;2KGW;2KSM;2L26;2LBT;2LCA;
|
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
|
arfA ompA Rv0899 MTCY31.27
| false |
Mycobacterium tuberculosis
| 978 |
row_23490
| false | null |
26,896 |
P9WKE3
|
MSHDWTDNRKNLMLFAGRAHPELAEQVAKELDVHVTSQDAREFANGEIFVRFHESVRGCDAFVLQSCPAPVNRWLMEQLIMIDALKRGSAKRITAVMPFYPYARQDKKHRGREPISARLIADLLKTAGADRIVTVDLHTDQIQGFFDGPVDHMRGQNLLTGYIRDNYPDGNMVVVSPDSGRVRIAEKWADALGGVPLAFIHKTRDPRVPNQVVSNRVVGDVAGRTCVLIDDMIDTGGTIAGAVALLHNDGAGDVIIAATHGVLSDPAAQRLASCGAREVIVTNTLPIGEDKRFPQLTVLSIAPLLASTIRAVFENGSVTGLFDGDA
|
Ribose-phosphate pyrophosphokinase (RPPK) (EC 2.7.6.1) (5-phospho-D-ribosyl alpha-1-diphosphate synthase) (Phosphoribosyl diphosphate synthase) (Phosphoribosyl pyrophosphate synthase) (P-Rib-PP synthase) (PRPP synthase) (PRPPase)
|
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
| 83,332 | 326 | 35,477 |
Allosteric enzyme;ATP-binding;Cell wall biogenesis/degradation;Cytoplasm;Isopeptide bond;Kinase;Magnesium;Manganese;Metal-binding;Nucleotide biosynthesis;Nucleotide-binding;Reference proteome;Transferase;Ubl conjugation
|
GO:0000287; GO:0002189; GO:0004749; GO:0005524; GO:0005737; GO:0005886; GO:0006015; GO:0006164; GO:0009156; GO:0009274; GO:0016301; GO:0030145; GO:0045227; GO:0071555
|
Evidence at protein level
| 5 |
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00583}.
| null | null |
PF14572;PF13793;
|
IPR000842;IPR029099;IPR000836;IPR029057;IPR005946;IPR037515;
| null |
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
|
prs prsA Rv1017c MTCY10G2.32
| false |
Mycobacterium tuberculosis
| 979 |
row_23537
| false | null |
112,137 |
A1KG30
|
MIPVLPPLEALLDRLYVVALPMRVRFRGITTREVALIEGPAGWGEFGAFVEYQSAQACAWLASAIETAYCAPPPVRRDRVPINATVPAVAAAQVGEVLARFPGARTAKVKVAEPGQSLADDIERVNAVRELVPMVRVDANGGWGVAEAVAAAAALTADGPLEYLEQPCATVAELAELRRRVDVPIAADESIRKAEDPLAVVRAQAADIAVLKVAPLGGISALLDIAARIAVPVVVSSALDSAVGIAAGLTAAAALPELDHACGLGTGGLFEEDVAEPAAPVDGFLAVARTTPDPARLQALGAPPQRRQWWIDRVKACYSLLVPSFG
|
o-succinylbenzoate synthase (OSB synthase) (OSBS) (EC 4.2.1.113) (4-(2'-carboxyphenyl)-4-oxybutyric acid synthase) (o-succinylbenzoic acid synthase)
|
Mycobacterium bovis (strain BCG / Pasteur 1173P2)
| 410,289 | 326 | 33,975 |
Lyase;Magnesium;Menaquinone biosynthesis;Metal-binding
|
GO:0000287; GO:0009234; GO:0043748
|
Inferred from homology
| 3 | null | null | null |
PF18374;PF13378;
|
IPR036849;IPR029065;IPR013342;IPR010196;
| null |
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype), Mycobacterium tuberculosis variant bovis BCG (no rank)
|
menC BCG_0598
| false |
Mycobacterium tuberculosis
| 980 |
row_100604
| false | null |
212,539 |
P9WHN9
|
MPELNTARGPIDTADLGVTLMHEHVFIMTTEIAQNYPEAWGDEDKRVAGAIARLGELKARGVDTIVDLTVIGLGRYIPRIARVAAATELNIVVATGLYTYNDVPFYFHYLGPGAQLDGPEIMTDMFVRDIEHGIADTGIKAGILKCATDEPGLTPGVERVLRAVAQAHKRTGAPISTHTHAGLRRGLDQQRIFAEEGVDLSRVVIGHCGDSTDVGYLEELIAAGSYLGMDRFGVDVISPFQDRVNIVARMCERGHADKMVLSHDACCYFDALPEELVPVAMPNWHYLHIHNDVIPALKQHGVTDEQLHTMLVDNPRRIFERQGGYQ
|
Phosphotriesterase homology protein
|
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
| 83,332 | 326 | 35,886 |
3D-structure;Hydrolase;Metal-binding;Reference proteome;Zinc
|
GO:0008270; GO:0009056; GO:0016788
|
Evidence at protein level
| 3 | null | null | null |
PF02126;
|
IPR017947;IPR032466;IPR001559;
|
4IF2;
|
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
|
php Rv0230c MTCY08D5.26c
| false |
Mycobacterium tuberculosis
| 981 |
row_198747
| false | null |
12,463 |
P0C2T2
|
MTDVSRKIRAWGRRLMIGTAAAVVLPGLVGLAGGAATAGAFSRPGLPVEYLQVPSPSMGRDIKVQFQSGGNNSPAVYLLDGLRAQDDYNGWDINTPAFEWYYQSGLSIVMPVGGQSSFYSDWYSPACGKAGCQTYKWETFLTSELPQWLSANRAVKPTGSAAIGLSMAGSSAMILAAYHPQQFIYAGSLSALLDPSQGMGPSLIGLAMGDAGGYKAADMWGPSSDPAWERNDPTQQIPKLVANNTRLWVYCGNGTPNELGGANIPAEFLENFVRSSNLKFQDAYNAAGGHNAVFNFPPNGTHSWEYWGAQLNAMKGDLQSSLGAG
|
Diacylglycerol acyltransferase/mycolyltransferase Ag85B (DGAT) (EC 2.3.1.122) (EC 2.3.1.20) (30 kDa extracellular protein) (Acyl-CoA:diacylglycerol acyltransferase) (Antigen 85 complex B) (85B) (Ag85B) (Extracellular alpha-antigen) (Fibronectin-binding protein B) (Fbps B)
|
Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
| 233,413 | 325 | 34,581 |
Acyltransferase;Direct protein sequencing;Disulfide bond;Reference proteome;Secreted;Signal;Transferase
|
GO:0004144; GO:0005576; GO:0050348
|
Evidence at protein level
| 5 |
SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
|
SIGNAL 1..40; /evidence="ECO:0000269|PubMed:2842287"
| null |
PF00756;
|
IPR029058;IPR000801;IPR050583;
| null |
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype)
|
fbpB BQ2027_MB1918C
| false |
Mycobacterium tuberculosis
| 982 |
row_10654
| false | null |
25,724 |
P80069
|
MHQVDPNLTRRKGRLAALAIAAMASASLVTVAVPATANADPEPAPPVPTTAASPPSTAAAPPAPATPVAPPPPAAANTPNAQPGDPNAAPPPADPNAPPPPVIAPNAPQPVRIDNPVGGFSFALPAGWVESDAAHLDYGSALLSKTTGDPPFPGQPPPVANDTRIVLGRLDQKLYASAEATDSKAAARLGSDMGEFYMPYPGTRINQETVSLDANGVSGSASYYEVKFSDPSKPNGQIWTGVIGSPAANAPDAGPPQRWFVVWLGTANNPVDKGAAKALAESIRPLVAPPPAPAPAPAEPAPAPAPAGEVAPTPTTPTPQRTLPA
|
Alanine and proline-rich secreted protein Apa (45/47 kDa antigen) (FAP-B) (Fibronectin attachment protein)
|
Mycobacterium bovis (strain BCG / Pasteur 1173P2)
| 410,289 | 325 | 32,687 |
Direct protein sequencing;Glycoprotein;Repeat;Secreted;Signal
|
GO:0005576; GO:0009986; GO:0050840
|
Evidence at protein level
| 5 |
SUBCELLULAR LOCATION: Secreted. Cell surface {ECO:0000269|PubMed:17158455}.
|
SIGNAL 1..39; /evidence="ECO:0000269|PubMed:8423100"
| null |
PF07174;
|
IPR010801;
| null |
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype), Mycobacterium tuberculosis variant bovis BCG (no rank)
|
apa modD BCG_1896
| false |
Mycobacterium tuberculosis
| 983 |
row_22490
| false | null |
26,380 |
P96379
|
MIVVLVDPRRPTLVPVEAIEFLRGEVQYTEEMPVAVPWSLPAARSAHAGNDAPVLLSSDPNHPAVITRLAAGARLISAPDSQRGERLVDAVAMMDKLRTAGPWESEQTHDSLRRYLLEETYELLDAVRSGSVDQLREELGDLLLQVLFHARIAEDASQSPFTIDDVADTLMRKLGNRAPGVLAGESISLEDQLAQWEAAKASEKARKSVADDVHTGQPALALAQKVIQRAQKAGLPAHLIPDEITSVSVSADVDAENTLRTAVLDFIDRLRCAERAIAVARRGSNVAEQLDVTPLGVITEQEWLAHWPTAVNDSRGGSKKRKGMR
|
Nucleoside triphosphate pyrophosphohydrolase (NTP-PPase) (EC 3.6.1.8)
|
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
| 83,332 | 325 | 35,413 |
3D-structure;ATP-binding;Hydrolase;Magnesium;Metal-binding;Nucleotide-binding;Reference proteome
|
GO:0000287; GO:0005524; GO:0006203; GO:0006979; GO:0009274; GO:0035539; GO:0046047; GO:0046052; GO:0046061; GO:0046076; GO:0046081; GO:0047429; GO:0047693; GO:0051289
|
Evidence at protein level
| 5 | null | null | null |
PF03819;
|
IPR004518;IPR048015;IPR011551;
|
7YH5;
|
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
|
mazG Rv1021
| false |
Mycobacterium tuberculosis
| 984 |
row_23092
| false | null |
67,925 |
O05572
|
MIPAVSLGDPQFTANVHDGIARITELINSELSQADEVMRDTVAHLVDAGGTPFRPLFTVLAAQLGSDPDGWEVTVAGAAIELMHLGTLCHDRVVDESDMSRKTPSDNTRWTNNFAILAGDYRFATASQLASRLDPEAFAVVAEAFAELITGQMRATRGPASHIDTIEHYLRVVHEKTGSLIAASGQLGAALSGAAEEQIRRVARLGRMIGAAFEISRDIIAISGDSATLSGADLGQAVHTLPMLYALREQTPDTSRLRELLAGPIHDDHVAEALTLLRCSPGIGKAKNVVAAYAAQAREELPYLPDRQPRRALATLIDHAISACD
|
Dimethylallyltranstransferase (EC 2.5.1.1) (Geranyl diphosphate synthase) (GPP synthase)
|
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
| 83,332 | 325 | 34,757 |
Lipid biosynthesis;Lipid metabolism;Magnesium;Metal-binding;Reference proteome;Transferase
|
GO:0004161; GO:0004659; GO:0008299; GO:0033384; GO:0046872
|
Evidence at protein level
| 4 | null | null | null |
PF00348;
|
IPR008949;IPR000092;
| null |
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
|
grcC2 Rv0989c
| false |
Mycobacterium tuberculosis
| 985 |
row_59017
| false | null |
212,355 |
P9WFZ7
|
MTRYLARRLLNYLVLLALASFLTYCLTSLAFSPLESLMQRSPRPPQAVIDAKAHDLGLDRPILARYANWVSHAVRGDFGTTITGQPVGTELGRRIGVSLRLLVVGSVFGTVAGVVIGAWGAIRQYRLSDRVMTTLALLVLSTPTFVVANLLILGALRVNWAVGIQLFDYTGETSPGVAGGVWDRLGDRLQHLILPSLTLALAAAAGFSRYQRNAMLDVLGQDFIRTARAKGLTRRRALLKHGLRTALIPMATLFAYGVAGLVTGAVFVEKIFGWHGMGEWMVRGISTQDTNIVAAITVFSGAVVLLAGLLSDVIYAALDPRVRVS
|
Oligopeptide transport system permease protein OppB
|
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
| 83,332 | 325 | 35,083 |
3D-structure;Cell inner membrane;Cell membrane;Membrane;Peptide transport;Protein transport;Reference proteome;Transmembrane;Transmembrane helix;Transport
|
GO:0005886; GO:0015031; GO:0015833; GO:0022857
|
Evidence at protein level
| 3 |
SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000269|PubMed:38548954}; Multi-pass membrane protein {ECO:0000269|PubMed:38548954}.
| null |
TRANSMEM 12..32; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 102..122; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 135..155; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 189..208; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 248..268; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 290..310; /note="Helical"; /evidence="ECO:0000255"
|
PF00528;PF19300;
|
IPR045621;IPR000515;IPR035906;
|
8J5Q;8J5R;8J5S;8J5T;
|
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
|
oppB Rv1283c MTCY373.02c
| false |
Mycobacterium tuberculosis
| 986 |
row_198567
| false | null |
321,044 |
A1KH25
|
MRTEDDSWDVTTSVGSTGLLVAAARALETQKADPLAIDPYAEVFCRAAGGEWADVLDGKLPDHYLTTGDFGEHFVNFQGARTRYFDEYFSRATAAGMKQVVILAAGLDSRAFRLQWPIGTTIFELDRPQVLDFKNAVLADYHIRPRAQRRSVAVDLRDEWQIALCNNGFDANRPSAWIAEGLLVYLSAEAQQRLFIGIDTLASPGSHVAVEEATPLDPCEFAAKLERERAANAQGDPRRFFQMVYNERWARATEWFDERGWRATATPLAEYLRRVGRAVPEADTEAAPMVTAITFVSAVRTGLVADPARTSPSSTSIGFKRFEAD
|
Putative S-adenosyl-L-methionine-dependent methyltransferase BCG_0945c (EC 2.1.1.-)
|
Mycobacterium bovis (strain BCG / Pasteur 1173P2)
| 410,289 | 325 | 36,073 |
Methyltransferase;S-adenosyl-L-methionine;Transferase
|
GO:0008168; GO:0032259
|
Inferred from homology
| 2 | null | null | null |
PF04072;
|
IPR007213;IPR029063;IPR011610;
| null |
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype), Mycobacterium tuberculosis variant bovis BCG (no rank)
|
BCG_0945c
| false |
Mycobacterium tuberculosis
| 987 |
row_304416
| false | null |
431,816 |
P9WLA1
|
MSQPPEHPGNPADPQGGNQGAGSYPPPGYGAPPPPPGYGPPPGTYLPPGYNAPPPPPGYGPPPGPPPPGYPTHLQSSGFSVGDAISWSWNRFTQNAVTLVVPVLAYAVALAAVIGATAGLVVALSDRATTAYTNTSGVSSESVDITMTPAAGIVMFLGYIALFALVLYMHAGILTGCLDIADGKPVTIATFFRPRNLGLVLVTGLLIVAVTFIGGLLCVIPGLIFGFVAQFAVAFAVDRSTSPIDSVKASIETVGSNIGGSVLSWLAQLTAVLVGELLCFVGMLIGIPVAALIHVYTYRKLSGGQVVEAVRPAPPVGWPPGPQLA
|
Uncharacterized protein Rv2560
|
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
| 83,332 | 325 | 33,124 |
Cell membrane;Membrane;Reference proteome;Transmembrane;Transmembrane helix
|
GO:0005886
|
Evidence at protein level
| 2 |
SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
| null |
TRANSMEM 96..116; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 153..173; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 205..225; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 273..293; /note="Helical"; /evidence="ECO:0000255"
| null | null | null |
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
|
Rv2560 MTCY9C4.08c
| false |
Mycobacterium tuberculosis
| 988 |
row_413571
| false | null |
1,312 |
A5U4N0
|
MTIAVTGSIATDHLMRFPGRFSEQLLPEHLHKVSLSFLVDDLVMHRGGVAGNMAFAIGVLGGEVALVGAAGADFADYRDWLKARGVNCDHVLISETAHTARFTCTTDVDMAQIASFYPGAMSEARNIKLADVVSAIGKPELVIIGANDPEAMFLHTEECRKLGLAFAADPSQQLARLSGEEIRRLVNGAAYLFTNDYEWDLLLSKTGWSEADVMAQIDLRVTTLGPKGVDLVEPDGTTIHVGVVPETSQTDPTGVGDAFRAGFLTGRSAGLGLERSAQLGSLVAVLVLESTGTQEWQWDYEAAASRLAGAYGEHAAAEIVAVLA
|
Adenosine kinase (ADK) (AK) (EC 2.7.1.20)
|
Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra)
| 419,947 | 324 | 34,472 |
ATP-binding;Direct protein sequencing;Kinase;Magnesium;Nucleotide-binding;Purine salvage;Reference proteome;Transferase
|
GO:0004001; GO:0005524; GO:0006166; GO:0044209
|
Evidence at protein level
| 5 | null | null | null |
PF00294;
|
IPR002173;IPR050306;IPR011611;IPR029056;
| null |
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
|
adoK cbhK MRA_2218
| false |
Mycobacterium tuberculosis
| 989 |
row_1068
| false | null |
26,777 |
P9WH71
|
MTGNAKLIDRVSAINWNRLQDEKDAEVWDRLTGNFWLPEKVPVSNDIPSWGTLTAGEKQLTMRVFTGLTMLDTIQGTVGAVSLIPDALTPHEEAVLTNIAFMESVHAKSYSQIFSTLCSTAEIDDAFRWSEENRNLQRKAEIVLQYYRGDEPLKRKVASTLLESFLFYSGFYLPMYWSSRAKLTNTADMIRLIIRDEAVHGYYIGYKFQRGLALVDDVTRAELKDYTYELLFELYDNEVEYTQDLYDEVGLTEDVKKFLRYNANKALMNLGYEALFPRDETDVNPAILSALSPNADENHDFFSGSGSSYVIGKAVVTEDDDWDF
|
Ribonucleoside-diphosphate reductase subunit beta nrdF2 (EC 1.17.4.1) (Ribonucleoside-diphosphate reductase nrdF2) (Ribonucleotide reductase R2-2 small subunit)
|
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
| 83,332 | 324 | 36,992 |
3D-structure;Deoxyribonucleotide synthesis;Iron;Metal-binding;Oxidoreductase;Reference proteome
|
GO:0004748; GO:0005971; GO:0006260; GO:0009263; GO:0046872
|
Evidence at protein level
| 5 | null | null | null |
PF00268;
|
IPR009078;IPR012348;IPR026494;IPR033909;IPR030475;IPR000358;
|
1UZR;8J4X;8J4Y;
|
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
|
nrdF2 Rv3048c
| false |
Mycobacterium tuberculosis
| 990 |
row_23423
| false | null |
26,944 |
P9WMW9
|
MTASELVAGDLAGGRAPGALPLDTTWHRPGWTIGELEAAKAGRTISVVLPALNEEATIESVIDSISPLVDGLVDELIVLDSGSTDDTEIRAIASGARVVSREQALPEVPVRPGKGEALWRSLAATSGDIVVFIDSDLINPHPLFVPWLVGPLLTGEGIQLVKSFYRRPLQVSDVTSGVCATGGGRVTELVARPLLAALRPELGCVLQPLSGEYAASRELLTSLPFAPGYGVEIGLLIDTFDRLGLDAIAQVNLGVRAHRNRPLDELGAMSRQVIATLLSRCGIPDSGVGLTQFLPGGPDDSDYTRHTWPVSLVDRPPMKVMRPR
|
Glucosyl-3-phosphoglycerate synthase (GpgS) (EC 2.4.1.266) (Retaining glucosyltransferase)
|
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
| 83,332 | 324 | 34,379 |
3D-structure;Calcium;Cobalt;Glycosyltransferase;Iron;Magnesium;Manganese;Metal-binding;Reference proteome;Transferase
|
GO:0000287; GO:0006011; GO:0016758; GO:0042803
|
Evidence at protein level
| 5 | null | null | null |
PF00535;
|
IPR001173;IPR050256;IPR029044;
|
3E25;3E26;4DDZ;4DE7;4DEC;4Y6N;4Y6U;4Y7F;4Y7G;4Y9X;5JQQ;5JQX;5JT0;5JUC;
|
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
|
gpgS Rv1208
| false |
Mycobacterium tuberculosis
| 991 |
row_23584
| false | null |
181,650 |
I6YEE1
|
MTWKGSGQETVGAEPTLWAISDLHTGHLGNKPVAESLYPSSPDDWLIVAGDVAERTDEIRWSLDLLRRRFAKVIWVPGNHELWTTNRDPMQIFGRARYDYLVNMCDEMGVVTPEHPFPVWTERGGPATIVPMFLLYDYSFLPEGANSKAEGVAIAKERNVVATDEFLLSPEPYPTRDAWCHERVAATRARLEQLDWMQPTVLVNHFPLLRQPCDALFYPEFSLWCGTTKTADWHTRYNAVCSVYGHLHIPRTTWYDGVRFEEVSVGYPREWRRRKPYSWLRQVLPDPQYAPGYLNDFGGHFVITPEMRTQAAQFRERLRQRQSR
|
[Acyl-carrier-protein] phosphodiesterase PptH (ACP phosphodiesterase PptH) (EC 3.1.4.14) (Ppt hydrolase)
|
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
| 83,332 | 324 | 37,601 |
3D-structure;Hydrolase;Iron;Manganese;Metal-binding;Reference proteome
|
GO:0008770; GO:0046872
|
Evidence at protein level
| 3 | null | null | null |
PF00149;
|
IPR004843;IPR029052;IPR052963;
|
6UNC;
|
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
|
pptH Rv2795c
| false |
Mycobacterium tuberculosis
| 992 |
row_168696
| false | null |
212,359 |
P9WG05
|
MVTEPLTKPALVAVDMRPARRGERLFKLAASAAGSTIVIAILLIAIFLLVRAVPSLRANHANFFTSTQFDTSDDEQLAFGVRDLFMVTALSSITALVLAVPVAVGIAVFLTHYAPRRLSRPFGAMVDLLAAVPSIIFGLWGIFVLAPKLEPIARFLNRNLGWLFLFKQGNVSLAGGGTIFTAGIVLSVMILPIVTSISREVFRQTPLIQIEAALALGATKWEVVRMTVLPYGRSGVVAASMLGLGRALGETVAVLVILRSAARPGTWSLFDGGYTFASKIASAASEFSEPLPTGAYISAGFALFVLTFLVNAAARAIAGGKVNG
|
Phosphate transport system permease protein PstC 2
|
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
| 83,332 | 324 | 34,262 |
Cell membrane;Membrane;Phosphate transport;Reference proteome;Transmembrane;Transmembrane helix;Transport
|
GO:0005315; GO:0005886; GO:0035435; GO:0051701
|
Evidence at protein level
| 3 |
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000255|PROSITE-ProRule:PRU00441}.
| null |
TRANSMEM 30..50; /note="Helical"; /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"; TRANSMEM 90..110; /note="Helical"; /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"; TRANSMEM 125..145; /note="Helical"; /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"; TRANSMEM 174..194; /note="Helical"; /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"; TRANSMEM 237..257; /note="Helical"; /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"; TRANSMEM 290..310; /note="Helical"; /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
|
PF00528;
|
IPR000515;IPR035906;IPR011864;IPR051124;
| null |
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
|
pstC2 Rv0929 MTCY21C12.23
| false |
Mycobacterium tuberculosis
| 993 |
row_198571
| false | null |
26,743 |
P9WGI5
|
MADAPTRATTSRVDSDLDAQSPAADLVRVYLNGIGKTALLNAAGEVELAKRIEAGLYAEHLLETRKRLGENRKRDLAAVVRDGEAARRHLLEANLRLVVSLAKRYTGRGMPLLDLIQEGNLGLIRAMEKFDYTKGFKFSTYATWWIRQAITRGMADQSRTIRLPVHLVEQVNKLARIKREMHQHLGREATDEELAAESGIPIDKINDLLEHSRDPVSLDMPVGSEEEAPLGDFIEDAEAMSAENAVIAELLHTDIRSVLATLDEREHQVIRLRFGLDDGQPRTLDQIGKLFGLSRERVRQIERDVMSKLRHGERADRLRSYAS
|
RNA polymerase sigma factor SigB
|
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
| 83,332 | 323 | 36,343 |
3D-structure;DNA-binding;Reference proteome;Sigma factor;Stress response;Transcription;Transcription regulation
|
GO:0001666; GO:0003677; GO:0005829; GO:0005886; GO:0006352; GO:0009408; GO:0009410; GO:0016987; GO:0043175; GO:0045893
|
Evidence at protein level
| 5 | null | null | null |
PF00140;PF04542;PF04539;PF04545;
|
IPR014284;IPR000943;IPR009042;IPR007627;IPR007624;IPR007630;IPR013325;IPR013324;IPR050239;IPR036388;
|
7PP4;7Q4U;7Q59;7ZF2;
|
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
|
sigB mysB Rv2710
| false |
Mycobacterium tuberculosis
| 994 |
row_23390
| false | null |
27,006 |
P9WP53
|
MTRYDSLLQALGNTPLVGLQRLSPRWDDGRDGPHVRLWAKLEDRNPTGSIKDRPAVRMIEQAEADGLLRPGATILEPTSGNTGISLAMAARLKGYRLICVMPENTSVERRQLLELYGAQIIFSAAEGGSNTAVATAKELAATNPSWVMLYQYGNPANTDSHYCGTGPELLADLPEITHFVAGLGTTGTLMGTGRFLREHVANVKIVAAEPRYGEGVYALRNMDEGFVPELYDPEILTARYSVGAVDAVRRTRELVHTEGIFAGISTGAVLHAALGVGAGALAAGERADIALVVADAGWKYLSTGAYAGSLDDAETALEGQLWA
|
O-phosphoserine sulfhydrylase (OPS sulfhydrylase) (EC 2.5.1.113) (CysO-thiocarboxylate-dependent cysteine synthase) (Cysteine synthase B) (CSase B) (O-phosphoserine-specific cysteine synthase) ([CysO sulfur-carrier protein]-thiocarboxylate-dependent cysteine synthase)
|
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
| 83,332 | 323 | 34,438 |
3D-structure;Amino-acid biosynthesis;Cysteine biosynthesis;Pyridoxal phosphate;Reference proteome;Transferase
|
GO:0004124; GO:0005737; GO:0005829; GO:0006535; GO:0019344; GO:0030170; GO:0032991; GO:0033847
|
Evidence at protein level
| 5 | null | null | null |
PF00291;
|
IPR005856;IPR050214;IPR001216;IPR001926;IPR036052;
|
3DKI;3DWG;3DWI;3FGP;5I6D;5I7A;5I7H;5I7O;5I7R;5IW8;5IWC;
|
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
|
cysM Rv1336 MTCY130.21
| false |
Mycobacterium tuberculosis
| 995 |
row_23645
| false | null |
69,597 |
O69721
|
MTRTVAAPPVCVLGLGLIGGSIMRAAAAAGREVFGYNRSVEGAHGARSDGFDAITDLNQTLTRAAATEALIVLAVPMPALPGMLAHIRKSAPGCPLTDVTSVKCAVLDEVTAAGLQARYVGGHPMTGTAHSGWTAGHGGLFNRAPWVVSVDDHVDPTVWSMVMTLALDCGAMVVPAKSDEHDAAAAAVSHLPHLLAEALAVTAAEVPLAFALAAGSFRDATRVAATAPDLVRAMCEANTGQLAPAADRIIDLLSRARDSLQSHGSIADLADAGHAARTRYDSFPRSDIVTVVIGADKWREQLAAAGRAGGVITSALPSLDSPQ
|
Prephenate dehydrogenase (PDH) (EC 1.3.1.12)
|
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
| 83,332 | 323 | 33,099 |
Amino-acid biosynthesis;Aromatic amino acid biosynthesis;Direct protein sequencing;NAD;Oxidoreductase;Reference proteome;Tyrosine biosynthesis
|
GO:0004665; GO:0006571; GO:0008977; GO:0070403
|
Evidence at protein level
| 4 | null | null | null |
PF20463;PF02153;
|
IPR008927;IPR036291;IPR046825;IPR046826;IPR050812;IPR003099;
| null |
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
|
tyrA Rv3754 RVBD_3754 P425_03907
| false |
Mycobacterium tuberculosis
| 996 |
row_60561
| false | null |
425,354 |
P63485
|
MKYLDVDGIGQVSRIGLGTWQFGSREWGYGDRYATGAARDIVKRARALGVTLFDTAEIYGLGKSERILGEALGDDRTEVVVASKVFPVAPFPAVIKNRERASARRLQLNRIPLYQIHQPNPVVPDSVIMPGMRDLLDSGDIGAAGVSNYSLARWRKADAALGRPVVSNQVHFSLAHPDALEDLVPFAELENRIVIAYSPLAQGLLGGKYGLENRPGGVRALNPLFGTENLRRIEPLLATLRAIAVDVDAKPAQVALAWLISLPGVVAIPGASSVEQLEFNVAAADIELSAQSRDALTDAARAFRPVSTGRFLTDMVREKVSRR
|
Uncharacterized oxidoreductase Mb2320 (EC 1.-.-.-)
|
Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
| 233,413 | 323 | 34,986 |
NADP;Oxidoreductase;Reference proteome
|
GO:0016491
|
Inferred from homology
| 2 | null | null | null |
PF00248;
|
IPR050523;IPR023210;IPR036812;
| null |
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype)
|
BQ2027_MB2320
| false |
Mycobacterium tuberculosis
| 997 |
row_407455
| false | null |
426,830 |
P67152
|
MDRQSAVAQLRAAAEQFARVHLDACDRWSVGLSGGPDSLALTAVAARLWPTTALIVDHGLQPGSATVAETARIQAISLGCVDARVLCVQVGAAGGREAAARSARYSALEEHRDGPVLLAHTLDDQAETVLLGLGRGSGARSIAGMRPYDPPWCRPLLGVRRSVTHAACRELGLTAWQDPHNTDRRFTRTRLRTEVLPLLEDVLGGGVAEALARTATALREDTDLIDTIAAQALPGAAVAGSRGQELSTSALTALPDAVRRRVIRGWLLAGGATGLTDRQIRGVDRLVTAWRGQGGVAVGSTLRGQRLVAGRRDGVLVLRREPV
|
tRNA(Ile)-lysidine synthase (EC 6.3.4.19) (tRNA(Ile)-2-lysyl-cytidine synthase) (tRNA(Ile)-lysidine synthetase)
|
Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
| 233,413 | 323 | 34,130 |
ATP-binding;Cytoplasm;Ligase;Nucleotide-binding;Reference proteome;tRNA processing
|
GO:0005524; GO:0005737; GO:0006400; GO:0032267
|
Inferred from homology
| 2 |
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01161}.
| null | null |
PF01171;PF09179;
|
IPR014729;IPR011063;IPR012094;IPR012795;IPR015262;
| null |
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype)
|
tilS BQ2027_MB3649C
| false |
Mycobacterium tuberculosis
| 998 |
row_408924
| false | null |
431,829 |
P9WLL1
|
MLATLSQIRAWSTEHLIDAAGYWTETADRWEDVFLQMRNQAHAIAWNGAGGDGLRQRTRADFSTVSGIADQLRRAATIARNGAGTIDAAQRRVMYAVEDAQDAGFNVGEDLSVTDTKTTQPAAVQAARLAQAQALAGDIRLRVGQLVAAENEVSGQLAATTGDVGNVRFAGAPVVAHSAVQLVDFFKQDGPTPPPPGAPHPSGGADGPYSDPITSMMLPPAGTEAPVSDATKRWVDNMVNELAARPPDDPIAVEARRLAFQALHRPCNSAEWTAAVAGFAGSSAGVVGTALAIPAGPADWALLGAALLGVGGSGAAVVNCATK
|
Uncharacterized protein Rv2077c
|
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
| 83,332 | 323 | 33,321 |
Cell membrane;Membrane;Reference proteome;Signal;Transmembrane;Transmembrane helix
|
GO:0005829; GO:0005886
|
Inferred from homology
| 2 |
SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
|
SIGNAL 1..45; /evidence="ECO:0000255"
|
TRANSMEM 269..289; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 290..310; /note="Helical"; /evidence="ECO:0000255"
| null | null | null |
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
|
Rv2077c MTCY49.16c
| false |
Mycobacterium tuberculosis
| 999 |
row_413584
| false | null |
181,651 |
I6YGS0
|
MGAPTERLVDTNGVRLRVVEAGEPGAPVVILAHGFPELAYSWRHQIPALADAGYHVLAPDQRGYGGSSRPEAIEAYDIHRLTADLVGLLDDVGAERAVWVGHDWGAVVVWNAPLLHADRVAAVAALSVPALPRAQVPPTQAFRSRFGENFFYILYFQEPGIADAELNGDPARTMRRMIGGLRPPGDQSAAMRMLAPGPDGFIDRLPEPAGLPAWISQEELDHYIGEFTRTGFTGGLNWYRNFDRNWETTADLAGKTISVPSLFIAGTADPVLTFTRTDRAAEVISGPYREVLIDGAGHWLQQERPGEVTAALLEFLTGLELR
|
Epoxide hydrolase A (EHB) (EC 3.3.2.10) (Epoxide hydrolase EphA)
|
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
| 83,332 | 322 | 35,097 |
Detoxification;Hydrolase;Reference proteome
|
GO:0004301; GO:0009636; GO:0016787; GO:0042803
|
Evidence at protein level
| 3 | null | null | null |
PF00561;
|
IPR000073;IPR029058;IPR000639;
| null |
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
|
ephA Rv3617
| false |
Mycobacterium tuberculosis
| 1,000 |
row_168697
| false | null |
209,148 |
P71730
|
MSEAKPLHLVLGDEELLVERAVADVLRSARQRAGTADVPVSRMRAGDVGAYELAELLSPSLFAEERIVVLGAAAEAGKDAAAVIESAAADLPAGTVLVVVHSGGGRAKSLANQLRSMGAQVHPCARITKVSERADFIRSEFASLRVKVDDETVTALLDAVGSDVRELASACSQLVADTGGAVDAAAVRRYHSGKAEVRGFDIADKAVAGDVAGAAEALRWAMMRGEPLVVLADALAEAVHTIGRVGPQSGDPYRLAAQLGMPPWRVQKAQKQARRWSRDTVATAMRLVAELNANVKGAVADADYALESAVRQVAELVADRGR
|
Probable DNA polymerase III subunit delta (EC 2.7.7.7)
|
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
| 83,332 | 322 | 33,757 |
Direct protein sequencing;DNA replication;DNA-directed DNA polymerase;Nucleotidyltransferase;Reference proteome;Transferase
|
GO:0003677; GO:0003887; GO:0006261; GO:0009360
|
Evidence at protein level
| 3 | null | null | null |
PF21694;
|
IPR008921;IPR048466;IPR005790;IPR027417;
| null |
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
|
holA Rv2413c
| false |
Mycobacterium tuberculosis
| 1,001 |
row_195548
| false | null |
212,491 |
P9WH72
|
MTGKLVERVHAINWNRLLDAKDLQVWERLTGNFWLPEKIPLSNDLASWQTLSSTEQQTTIRVFTGLTLLDTAQATVGAVAMIDDAVTPHEEAVLTNMAFMESVHAKSYSSIFSTLCSTKQIDDAFDWSEQNPYLQRKAQIIVDYYRGDDALKRKASSVMLESFLFYSGFYLPMYWSSRGKLTNTADLIRLIIRDEAVHGYYIGYKCQRGLADLTDAERADHREYTCELLHTLYANEIDYAHDLYDELGWTDDVLPYMRYNANKALANLGYQPAFDRDTCQVNPAVRAALDPGAGENHDFFSGSGSSYVMGTHQPTTDTDWDF
|
Ribonucleoside-diphosphate reductase subunit beta nrdF1 (EC 1.17.4.1) (Ribonucleotide reductase R2-1 small subunit) (Ribonucleotide reductase small subunit 1)
|
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
| 83,331 | 322 | 36,590 |
Deoxyribonucleotide synthesis;Iron;Metal-binding;Oxidoreductase;Reference proteome
|
GO:0004748; GO:0005971; GO:0009263; GO:0046872
|
Inferred from homology
| 3 | null | null | null |
PF00268;
|
IPR009078;IPR012348;IPR026494;IPR033909;IPR030475;IPR000358;
| null |
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
|
nrdF1 MT2033
| false |
Mycobacterium tuberculosis
| 1,002 |
row_198699
| false | null |
321,181 |
A1KPR5
|
MPGNSRRRGAVRKSGTKKGAGVGSGGQRRRGLEGRGPTPPAHLRPHHPAAKRARAQPRRPVKRADETETVLGRNPVLECLRAGVPATALYVALGTEADERLTECVARAADSGIAIVELLRADLDRMTANHLHQGIALQVPPYNYAHPDDLLAAALDQPPALLVALDNLSDPRNLGAIVRSVAAFGGHGVLIPQRRSASVTAVAWRTSAGAAARIPVARATNLTRTLKGWADRGVRVIGLDAGGGTALDDVDGTDSLVVVVGSEGKGLSRLVRQNCDEVVSIPMAAQAESLNASVAAGVVLAAIARQRRRPREPREQTQNRMI
|
Uncharacterized tRNA/rRNA methyltransferase BCG_3644c (EC 2.1.1.-)
|
Mycobacterium bovis (strain BCG / Pasteur 1173P2)
| 410,289 | 322 | 33,952 |
Methyltransferase;S-adenosyl-L-methionine;Transferase
|
GO:0003723; GO:0005829; GO:0006396; GO:0008173; GO:0032259
|
Inferred from homology
| 2 | null | null | null |
PF00588;PF08032;
|
IPR029028;IPR029064;IPR004441;IPR001537;IPR013123;IPR029026;
| null |
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype), Mycobacterium tuberculosis variant bovis BCG (no rank)
|
BCG_3644c
| false |
Mycobacterium tuberculosis
| 1,003 |
row_304553
| false | null |
26,822 |
P9WIC3
|
MVRIAYLGPEGTFTEAALVRMVAAGLVPETGPDALQRMPVESAPAALAAVRDGGADYACVPIENSIDGSVLPTLDSLAIGVRLQVFAETTLDVTFSIVVKPGRNAADVRTLAAFPVAAAQVRQWLAAHLPAADLRPAYSNADAARQVADGLVDAAVTSPLAAARWGLAALADGVVDESNARTRFVLVGRPGPPPARTGADRTSAVLRIDNQPGALVAALAEFGIRGIDLTRIESRPTRTELGTYLFFVDCVGHIDDEAVAEALKAVHRRCADVRYLGSWPTGPAAGAQPPLVDEASRWLARLRAGKPEQTLVRPDDQGAQA
|
Prephenate dehydratase (PDT) (EC 4.2.1.51)
|
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
| 83,332 | 321 | 33,633 |
Allosteric enzyme;Amino-acid biosynthesis;Aromatic amino acid biosynthesis;Lyase;Phenylalanine biosynthesis;Reference proteome
|
GO:0004664; GO:0005737; GO:0009094; GO:0016597; GO:0033585; GO:0042803
|
Evidence at protein level
| 5 | null | null | null |
PF01842;PF00800;
|
IPR045865;IPR002912;IPR008242;IPR001086;IPR018528;
| null |
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
|
pheA Rv3838c
| false |
Mycobacterium tuberculosis
| 1,004 |
row_23467
| false | null |
212,935 |
P9WN46
|
MRVSVANHLGEDAGHLALRRDVYSGLQKTPKSLPPKWFYDTVGSELFDQITRLPEYYPTRAEAEILRARSAEVASACRADTLVELGSGTSEKTRMLLDALRHRGSLRRFVPFDVDASVLSATATAIQREYSGVEINAVCGDFEEHLTEIPRGGRRLFVFLGSTIGNLTPGPRAQFLTALAGVMRPGDSLLLGTDLVKDAARLVRAYDDPGGVTAQFNRNVLAVINRELEADFDVDAFQHVARWNSAEERIEMWLRADGRQRVRVGALDLTVDFDAGEEMLTEVSCKFRPQAVGAELAAAGLHRIRWWTDEAGDFGLSLAAK
|
Histidine N-alpha-methyltransferase (EC 2.1.1.44) (Histidine trimethyltransferase)
|
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
| 83,331 | 321 | 35,404 |
Methyltransferase;Reference proteome;S-adenosyl-L-methionine;Transferase
|
GO:0008276; GO:0032259; GO:0052704; GO:0052706
|
Evidence at transcript level
| 3 | null | null | null |
PF10017;
|
IPR035094;IPR032888;IPR051128;IPR019257;IPR017804;IPR029063;
| null |
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
|
egtD MT3804
| false |
Mycobacterium tuberculosis
| 1,005 |
row_199137
| false | null |
431,899 |
P9WMF6
|
MTPAQLRAYSAVVRLGSVRAAAAELGLSDAGVSMHVAALRKELDDPLFTRTGAGLAFTPGGLRLASRAVEILGLQQQTAIEVTEAAHGRRLLRIAASSAFAEHAAPGLIELFSSRADDLSVELSVHPTSRFRELICSRAVDIAIGPASESSIGSDGSIFLRPFLKYQIITVVAPNSPLAAGIPMPALLRHQQWMLGPSAGSVDGEIATMLRGLAIPESQQRIFQSDAAALEEVMRVGGATLAIGFAVAKDLAAGRLVHVTGPGLDRAGEWCVATLAPSARQPAVSELVGFISTPRCIQAMIPGSGVGVTRFRPKVHVTLWS
|
Uncharacterized HTH-type transcriptional regulator MT0391
|
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
| 83,331 | 321 | 33,637 |
DNA-binding;Reference proteome;Transcription;Transcription regulation
|
GO:0000976; GO:0003700
|
Inferred from homology
| 2 | null | null | null |
PF00126;PF03466;
|
IPR005119;IPR000847;IPR036388;IPR036390;
| null |
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
|
MT0391
| false |
Mycobacterium tuberculosis
| 1,006 |
row_413654
| false | null |
62,172 |
A5U3S4
|
MAIGEQQVIVIGAGVSGLTSAICLAEAGWPVRVWAAALPQQTTSAVAGAVWGPRPKEPVAKVRGWIEQSLHVFRDLAKDPATGVRMTPALSVGDRIETGAMPPGLELIPDVRPADPADVPGGFRAGFHATLPMIDMPQYLDCLTQRLAATGCEIETRPLRSLAEAAEAAPIVINCAGLGARELAGDATVWPRFGQHVVLTNPGLEQLFIERTGGSEWICYFAHPQRVVCGGISIPGRWDPTPEPEITERILQRCRRIQPRLAEAAVIETITGLRPDRPSVRVEAEPIGRALCIHNYGHGGDGVTLSWGCAREVVNLVGGG
|
D-amino-acid oxidase (DAAO) (DAMOX) (DAO) (EC 1.4.3.3)
|
Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra)
| 419,947 | 320 | 34,108 |
Cell wall;Cytoplasm;FAD;Flavoprotein;Oxidoreductase;Reference proteome;Secreted
|
GO:0003884; GO:0005576; GO:0005737; GO:0006546; GO:0009060; GO:0009274; GO:0019478; GO:0071949
|
Evidence at transcript level
| 4 |
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:26531045}. Secreted, cell wall {ECO:0000269|PubMed:26531045}. Note=Predominantly cytoplasmic. {ECO:0000269|PubMed:26531045}.
| null | null |
PF01266;
|
IPR023209;IPR006076;
| null |
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
|
dao MRA_1916
| false |
Mycobacterium tuberculosis
| 1,007 |
row_53837
| false | null |
80,307 |
P71668
|
MPSLDNTADEKPAIDPILLKVLDAVPFRLSIDDGIEAVRQRLRDLPRQPVHPELRVVDLAIDGPAGPIGTRIYWPPTCPDQAEAPVVLYFHGGGFVMGDLDTHDGTCRQHAVGADAIVVSVDYRLAPEHPYPAAIEDAWAATRWVAEHGRQVGADLGRIAVAGDSAGGTIAAVIAQRARDMGGPPIVFQLLWYPSTLWDQSLPSLAENADAPILDVKAIAAFSRWYAGEIDLHNPPAPMAPGRAENLADLPPAYIAVAGYDPLRDDGIRYGELLAAAGVPVEVHNAQTLVHGYVGYAGVVPAATEATNRGLVALRVVLHG
|
Esterase LipI (EC 3.1.1.-)
|
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
| 83,332 | 320 | 34,053 |
Hydrolase;Reference proteome
|
GO:0008126; GO:0034338
|
Evidence at protein level
| 4 | null | null | null |
PF07859;
|
IPR013094;IPR029058;IPR050300;IPR002168;IPR033140;
| null |
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
|
lipI Rv1400c
| false |
Mycobacterium tuberculosis
| 1,008 |
row_70823
| false | null |
279,263 |
Q7TX80
|
MARCDVLVSADWAESNLHAPKVVFVEVDEDTSAYDRDHIAGAIKLDWRTDLQDPVKRDFVDAQQFSKLLSERGIANEDTVILYGGNNNWFAAYAYWYFKLYGHEKVKLLDGGRKKWELDGRPLSSDPVSRPVTSYTASPPDNTIRAFRDEVLAAINVKNLIDVRSPDEFSGKILAPAHLPQEQSQRPGHIPGAINVPWSRAANEDGTFKSDEELAKLYADAGLDNSKETIAYCRIGERSSHTWFVLRELLGHQNVNIAFGYGPHACPASAYSRMCLTTFFTSLTQRFPQLQLARPFEDLERRGKGLHSVGIKELLVTWPT
|
Putative thiosulfate sulfurtransferase 2 (EC 2.8.1.1) (Rhodanese-like protein 2)
|
Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
| 233,413 | 320 | 35,999 |
Reference proteome;Repeat;Transferase
|
GO:0004497; GO:0004792; GO:0005506; GO:0016705; GO:0020037
|
Inferred from homology
| 3 | null | null | null |
PF00581;
|
IPR017972;IPR036396;IPR001763;IPR036873;IPR051126;
| null |
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype)
|
cysA2 BQ2027_MB3144
| false |
Mycobacterium tuberculosis
| 1,009 |
row_263587
| false | null |
26,888 |
P9WK87
|
MTEPTVARPDIDPVLKMLLDTFPVTFTAADGVEVARARLRQLKTPPELLPELRIEERTVGYDGLTDIPVRVYWPPVVRDNLPVVVYYHGGGWSLGGLDTHDPVARAHAVGAQAIVVSVDYRLAPEHPYPAGIDDSWAALRWVGENAAELGGDPSRIAVAGDSAGGNISAVMAQLARDVGGPPLVFQLLWYPTTMADLSLPSFTENADAPILDRDVIDAFLAWYVPGLDISDHTMLPTTLAPGNADLSGLPPAFIGTAEHDPLRDDGACYAELLTAAGVSVELSNEPTMVHGYVNFALVVPAAAEATGRGLAALKRALHA
|
Carboxylesterase NlhH (EC 3.1.1.1) (NLH-H)
|
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
| 83,332 | 319 | 33,906 |
Acetylation;Hydrolase;Reference proteome;Serine esterase
|
GO:0008126; GO:0009056; GO:0034338; GO:0106435
|
Evidence at protein level
| 5 | null | null | null |
PF07859;
|
IPR013094;IPR029058;IPR050300;
| null |
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
|
nlhH lipH Rv1399c
| false |
Mycobacterium tuberculosis
| 1,010 |
row_23529
| false | null |
112,169 |
A1KIG9
|
MTPRHLLTAADLSRDDATAILDDADRFAQALVGRDIKKLPTLRGRTVVTMFYENSTRTRVSFEVAGKWMSADVINVSAAGSSVGKGESLRDTALTLRAAGADALIIRHPASGAAHLLAQWTGAHNDGPAVINAGDGTHEHPTQALLDALTIRQRLGGIEGRRIVIVGDILHSRVARSNVMLLDTLGAEVVLVAPPTLLPVGVTGWPATVSHDFDAELPAADAVLMLRVQAERMNGGFFPSVREYSVRYGLTERRQAMLPGHAVVLHPGPMVRGMEITSSVADSSQSAVLQQVSNGVQVRMAVLFHVLVGAQDAGKEGAA
|
Aspartate carbamoyltransferase catalytic subunit (EC 2.1.3.2) (Aspartate transcarbamylase) (ATCase)
|
Mycobacterium bovis (strain BCG / Pasteur 1173P2)
| 410,289 | 319 | 33,819 |
Pyrimidine biosynthesis;Transferase
|
GO:0004070; GO:0005829; GO:0006207; GO:0006520; GO:0016597; GO:0044205
|
Inferred from homology
| 3 | null | null | null |
PF00185;PF02729;
|
IPR006132;IPR006130;IPR036901;IPR002082;IPR006131;
| null |
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype), Mycobacterium tuberculosis variant bovis BCG (no rank)
|
pyrB BCG_1441
| false |
Mycobacterium tuberculosis
| 1,011 |
row_100634
| false | null |
181,881 |
L7N5A6
|
MALTRVAAIDCGTNSIRLLIADVGAGLARGELHDVHRETRIVRLGQGVDATGRFAPEAIARTRTALTDYAELLTFHHAERVRMVATSAARDVVNRDVFFAMTADVLGAALPGSAAEVITGAEEAELSFRGAVGELGSAGAPFVVVDLGGGSTEIVLGEHEVVASYSADIGCVRLTERCLHSDPPTLQEVSTARRLVRERLEPALRTVPLELARTWVGLAGTMTTLSALAQSMTAYDAAAIHLSRVPGADLLEVCQRLIGMTRKQRAALAPMHPGRADVIGGGAIVVEELARELRERAGIDQLTVSEHDILDGIALSLAG
|
Exopolyphosphatase 2 (ExopolyPase 2) (EC 3.6.1.11) (PPX2)
|
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
| 83,331 | 319 | 33,664 |
Hydrolase;Reference proteome
|
GO:0004309
|
Evidence at protein level
| 3 | null | null | null |
PF02541;
|
IPR043129;IPR050273;IPR003695;
| null |
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
|
ppx2 MT1054
| false |
Mycobacterium tuberculosis
| 1,012 |
row_168918
| false | null |
546,977 |
P9WLV8
|
MVPGDASSVVSVNPAKPLISVCIPMYNNGATIERCLRSILEQEGVEFEIVVVDDDSSDDCAAIAATMLRPGDRLLRNEPRLGLNRNHNKCLEVARGGLIQFVHGDDRLLPGALQTLSRRFEDPSVGMAFAPRRVESDDIKWQQRYGRVHTRFRKLRDRNHGPSLVLQMVLHGAKENWIGEPTAVMFRRQLALDAGGFRTDIYQLVDVDFWLRLMLRSAVCFVPHELSVRRHTAATETTRVMATRRNVLDRQRILTWLIVDPLSPNSVRSAAALWWIPAWLAMIVEVAVLGPQRRTHLKALAPAPFREFAHARRQLPMAD
|
Uncharacterized protein MT1568
|
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
| 83,331 | 319 | 36,089 |
Membrane;Reference proteome;Transmembrane;Transmembrane helix
|
GO:0016020
|
Predicted
| 1 |
SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
| null |
TRANSMEM 270..290; /note="Helical"; /evidence="ECO:0000255"
|
PF00535;
|
IPR001173;IPR050834;IPR029044;
| null |
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
|
MT1568
| false |
Mycobacterium tuberculosis
| 1,013 |
row_527069
| false | null |
27,008 |
P9WP65
|
MHRLRAAEHPRPDYVLLHISDTHLIGGDRRLYGAVDADDRLGELLEQLNQSGLRPDAIVFTGDLADKGEPAAYRKLRGLVEPFAAQLGAELVWVMGNHDDRAELRKFLLDEAPSMAPLDRVCMIDGLRIIVLDTSVPGHHHGEIRASQLGWLAEELATPAPDGTILALHHPPIPSVLDMAVTVELRDQAALGRVLRGTDVRAILAGHLHYSTNATFVGIPVSVASATCYTQDLTVAAGGTRGRDGAQGCNLVHVYPDTVVHSVIPLGGGETVGTFVSPGQARRKIAESGIFIEPSRRDSLFKHPPMVLTSSAPRSPVD
|
cAMP/cGMP dual specificity phosphodiesterase Rv0805 (EC 3.1.4.16) (EC 3.1.4.17) (2',3'-cyclic-nucleotide phosphodiesterase) (3',5'-cyclic-nucleotide phosphodiesterase) (Cyclic nucleotide phosphodiesterase)
|
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
| 83,332 | 318 | 34,233 |
3D-structure;cAMP;Cell membrane;Cell wall;cGMP;Cytoplasm;Hydrolase;Iron;Manganese;Membrane;Metal-binding;Nucleotide-binding;Phosphoprotein;Reference proteome;Secreted
|
GO:0000166; GO:0004115; GO:0005506; GO:0005576; GO:0005737; GO:0005886; GO:0008199; GO:0008663; GO:0009274; GO:0030145; GO:0030313; GO:0042301; GO:0042545; GO:0047555
|
Evidence at protein level
| 5 |
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:19801656, ECO:0000269|PubMed:24970891}. Cell membrane {ECO:0000269|PubMed:19801656, ECO:0000269|PubMed:24970891}. Secreted, cell wall {ECO:0000269|PubMed:19801656, ECO:0000269|PubMed:24970891, ECO:0000269|PubMed:26904001}. Cell envelope {ECO:0000269|PubMed:24970891}. Note=The C-terminal extension (CTE) is necessary for the localization to the cell wall and cell envelope (PubMed:19801656, PubMed:24970891). Phosphorylation at Thr-309 promotes cell wall localization (PubMed:26904001). {ECO:0000269|PubMed:19801656, ECO:0000269|PubMed:24970891, ECO:0000269|PubMed:26904001}.
| null | null |
PF00149;
|
IPR004843;IPR050884;IPR026575;IPR029052;
|
2HY1;2HYO;2HYP;3IB7;3IB8;
|
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
|
Rv0805
| false |
Mycobacterium tuberculosis
| 1,014 |
row_23647
| false | null |
81,814 |
P9WKG7
|
MSASDGNTAELWVPTGSVTVRVPGKVNLYLAVGDRREDGYHELTTVFHAVSLVDEVTVRNADVLSLELVGEGADQLPTDERNLAWQAAELMAEHVGRAPDVSIMIDKSIPVAGGMAGGSADAAAVLVAMNSLWELNVPRRDLRMLAARLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFADSGLLTSAVYNELDRLREVGDPPRLGEPGPVLAALAAGDPDQLAPLLGNEMQAAAVSLDPALARALRAGVEAGALAGIVSGSGPTCAFLCTSASSAIDVGAQLSGAGVCRTVRVATGPVPGARVVSAPTEV
|
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase (CMK) (EC 2.7.1.148) (4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase) [Cleaved into: 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, propeptide removed]
|
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
| 83,332 | 318 | 32,613 |
3D-structure;ATP-binding;Direct protein sequencing;Isoprene biosynthesis;Kinase;Nucleotide-binding;Reference proteome;Transferase
|
GO:0005524; GO:0016114; GO:0019288; GO:0050515
|
Evidence at protein level
| 4 | null | null | null |
PF08544;PF00288;
|
IPR013750;IPR036554;IPR006204;IPR004424;IPR020568;IPR014721;
|
3PYD;3PYE;3PYF;3PYG;
|
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
|
ispE Rv1011 MTCI237.28
| false |
Mycobacterium tuberculosis
| 1,015 |
row_72260
| false | null |
181,648 |
I6YCF5
|
MTPPEERQMLRETVASLVAKHAGPAAVRAAMASDRGYDESLWRLLCEQVGAAALVIPEELGGAGGELADAAIVVQELGRALVPSPLLGTTLAELALLAAAKPDAQALTELAQGSAIGALVLDPDYVVNGDIADIVVAATSGQLTRWTRFSAQPVATMDPTRRLARLQSEETEPLCPDPGIADTAAILLAAEQIGAAERCLQLTVEYAKSRVQFGRPIGSFQALKHRMADLYVTIAAARAVVADACHAPTPTNAATARLAASEALSTAAAEGIQLHGGIAITWEHDMHLYFKRAHGSAQLLESPREVLRRLESEVWESP
|
Acyl-CoA dehydrogenase IpdE2 (EC 1.3.99.-) (5OH-HIP-CoA dehydrogenase beta subunit)
|
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
| 83,332 | 318 | 33,558 |
Cholesterol metabolism;FAD;Flavoprotein;Lipid metabolism;Oxidoreductase;Reference proteome;Steroid metabolism;Sterol metabolism
|
GO:0003995; GO:0006707; GO:0050660
|
Evidence at protein level
| 3 | null | null | null |
PF00441;PF02771;
|
IPR036250;IPR009075;IPR013786;IPR037069;IPR009100;
| null |
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
|
ipdE2 fadE33 Rv3564
| false |
Mycobacterium tuberculosis
| 1,016 |
row_168694
| false | null |
212,839 |
P9WLT1
|
MPAGLPGQASVAVRLSCDVPPDARHHEPRPGMTDHPDTGNGIGLTGRPPRAIPDPAPRSSHGPAKVIAMCNQKGGVGKTTSTINLGAALGEYGRRVLLVDMDPQGALSAGLGVPHYELDKTIHNVLVEPRVSIDDVLIHSRVKNMDLVPSNIDLSAAEIQLVNEVGREQTLARALYPVLDRYDYVLIDCQPSLGLLTVNGLACTDGVIIPTECEFFSLRGLALLTDTVDKVRDRLNPKLDISGILITRYDPRTVNSREVMARVVERFGDLVFDTVITRTVRFPETSVAGEPITTWAPKSAGALAYRALARELIDRFGM
|
Uncharacterized protein Rv1708
|
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
| 83,332 | 318 | 34,380 |
ATP-binding;Nucleotide-binding;Reference proteome
|
GO:0005524; GO:0005886; GO:0043590
|
Evidence at protein level
| 3 | null | null | null |
PF13614;
|
IPR025669;IPR050678;IPR027417;
| null |
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
|
Rv1708
| false |
Mycobacterium tuberculosis
| 1,017 |
row_199043
| false | null |
212,975 |
P9WNC9
|
MRSTPPASAGRSTPPALAGHSTPPALAGHSTLCGRPVAGDRALIMAIVNRTPDSFYDKGATFSDAAARDAVHRAVADGADVIDVGGVKAGPGERVDVDTEITRLVPFIEWLRGAYPDQLISVDTWRAQVAKAACAAGADLINDTWGGVDPAMPEVAAEFGAGLVCAHTGGALPRTRPFRVSYGTTTRGVVDAVISQVTAAAERAVAAGVAREKVLIDPAHDFGKNTFHGLLLLRHVADLVMTGWPVLMALSNKDVVGETLGVDLTERLEGTLAATALAAAAGARMFRVHEVAATRRVLEMVASIQGVRPPTRTVRGLA
|
Inactive dihydropteroate synthase 2 (DHPS 2) (Dihydropteroate pyrophosphorylase 2)
|
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
| 83,332 | 318 | 33,046 |
3D-structure;Reference proteome
|
GO:0005829; GO:0009396
|
Evidence at protein level
| 3 | null | null | null |
PF00809;
|
IPR045031;IPR006390;IPR011005;IPR000489;
|
2VP8;
|
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
|
folP2 Rv1207 MTCI364.19
| false |
Mycobacterium tuberculosis
| 1,018 |
row_199176
| false | null |
212,990 |
P9WNG9
|
MAEVLVLVEHAEGALKKVSAELITAARALGEPAAVVVGVPGTAAPLVDGLKAAGAAKIYVAESDLVDKYLITPAVDVLAGLAESSAPAGVLIAATADGKEIAGRLAARIGSGLLVDVVDVREGGVGVHSIFGGAFTVEAQANGDTPVITVRAGAVEAEPAAGAGEQVSVEVPAAAENAARITAREPAVAGDRPELTEATIVVAGGRGVGSAENFSVVEALADSLGAAVGASRAAVDSGYYPGQFQVGQTGKTVSPQLYIALGISGAIQHRAGMQTSKTIVAVNKDEEAPIFEIADYGVVGDLFKVAPQLTEAIKARKG
|
Electron transfer flavoprotein subunit alpha (Alpha-ETF) (Electron transfer flavoprotein large subunit) (ETFLS)
|
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
| 83,332 | 318 | 31,691 |
Electron transport;FAD;Flavoprotein;Reference proteome;Transport
|
GO:0005829; GO:0005886; GO:0009055; GO:0009274; GO:0033539; GO:0050660
|
Evidence at protein level
| 3 | null | null | null |
PF01012;PF00766;
|
IPR029035;IPR014730;IPR001308;IPR033947;IPR014731;IPR018206;IPR014729;
| null |
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
|
etfA fixB Rv3028c MTV012.43c
| false |
Mycobacterium tuberculosis
| 1,019 |
row_199191
| false | null |
321,038 |
A1KGL2
|
MTQTGSARFEGDSWDLASSVGLTATMVAAARAVAGRAPGALVNDQFAEPLVRAVGVDFFVRMASGELDPDELAEDEANGLRRFADAMAIRTHYFDNFFLDATRAGIRQAVILASGLDSRAYRLRWPAGTIVFEVDQPQVIDFKTTTLAGLGAAPTTDRRTVAVDLRDDWPTALQKAGFDNAQRTAWIAEGLLGYLSAEAQDRLLDQITAQSVPGSQFATEVLRDINRLNEEELRGRMRRLAERFRRHGLDLDMSGLVYFGDRTDARTYLADHGWRTASASTTDLLAEHGLPPIDGDDAPFGEVIYVSAELKQKHQDTR
|
Putative S-adenosyl-L-methionine-dependent methyltransferase BCG_0781c (EC 2.1.1.-)
|
Mycobacterium bovis (strain BCG / Pasteur 1173P2)
| 410,289 | 318 | 34,950 |
Methyltransferase;S-adenosyl-L-methionine;Transferase
|
GO:0008168; GO:0032259
|
Inferred from homology
| 2 | null | null | null |
PF04072;
|
IPR007213;IPR029063;IPR011610;
| null |
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype), Mycobacterium tuberculosis variant bovis BCG (no rank)
|
BCG_0781c
| false |
Mycobacterium tuberculosis
| 1,020 |
row_304410
| false | null |
430,690 |
P95279
|
MFVGRVGPVDRRSDGERSRRPREFEYIRYETIDDGRIAAITLDRPKQRNAQTRGMLVELGAAFELAEADDTVRVVILRAAGPAFSAGHDLGSADDIRERSPGPDQHPSYRCNGATFGGVESRNRQEWHYYFENTKRWRNLRKITIAQVHGAVLSAGLMLAWCCDLIVASEDTVFADVVGTRLGMCGVEYFGHPWEFGPRKTKELLLTGDCIGADEAHALGMVSKVFPADELATSTIEFARRIAKVPTMAALLIKESVNQTVDAMGFSAALDGCFKIHQLNHAHWGEVTGGKLSYGTVEYGLEDWRAAPQIRPAIKQRP
|
Putative enoyl-CoA hydratase EchA13
|
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
| 83,332 | 318 | 35,250 |
Fatty acid metabolism;Lipid metabolism;Lyase;Reference proteome
|
GO:0006635; GO:0016829
|
Evidence at transcript level
| 2 | null | null | null |
PF00378;
|
IPR029045;IPR001753;
| null |
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
|
echA13 Rv1935c
| false |
Mycobacterium tuberculosis
| 1,021 |
row_412452
| false | null |
432,058 |
P9WNU2
|
MRSPLVLLDGASMWFRSFFGVPSSITAPDGRPVNAVRGFIDSMAVVITQQRPNRLAVCLDLDWRPQFRVDLIPSYKAHRVAEPEPNGQPDVEEVPDELTPQVDMIMELLDAFGIAMAGAPGFEADDVLGTLATRERRDPVIVVSGDRDLLQVVADDPVPVRVLYLGRGLAKATLFGPAEVAERYGLPAHRAGAAYAELALLRGDPSDGLPGVPGVGEKTAATLLARHGSLDQIMAAADDRKTTMAKGLRTKLLAASAYIKAADRVVRVATDAPVTLSTPTDRLPLVAADPERTAELATRFGVESSIARLQKALDTLPG
|
5'-3' exonuclease (EC 3.1.11.-)
|
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
| 83,331 | 318 | 33,989 |
DNA-binding;Exonuclease;Hydrolase;Nuclease;Reference proteome
|
GO:0003677; GO:0008409; GO:0017108; GO:0033567
|
Inferred from homology
| 2 | null | null | null |
PF01367;PF02739;
|
IPR020046;IPR002421;IPR036279;IPR020045;IPR038969;IPR008918;IPR029060;
| null |
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
|
MT2151
| false |
Mycobacterium tuberculosis
| 1,022 |
row_413803
| false | null |
6,624 |
O53547
|
MKLTESNRSPRTTNTTDLSGKVAVVTGAAAGLGRAEALGLARLGATVVVNDVASALDASDVVDEIGAAAADAGAKAVAVAGDISQRATADELLASAVGLGGLDIVVNNAGITRDRMLFNMSDEEWDAVIAVHLRGHFLLTRNAAAYWRDKAKDAEGGSVFGRLVNTSSEAGLVGPVGQANYAAAKAGITALTLSAARALGRYGVCANVICPRARTAMTADVFGAAPDVEAGQIDPLSPQHVVSLVQFLASPAAAEVNGQVFIVYGPQVTLVSPPHMERRFSADGTSWDPTELTATLRDYFAGRDPEQSFSATDLMRQ
|
Hydroxyacyl-CoA dehydrogenase ChsB1 (EC 1.1.1.-)
|
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
| 83,332 | 317 | 32,753 |
3D-structure;Cholesterol metabolism;Lipid metabolism;NAD;Oxidoreductase;Reference proteome;Steroid metabolism;Sterol metabolism
|
GO:0003857; GO:0004300; GO:0006635; GO:0006707
|
Evidence at protein level
| 5 | null | null | null |
PF00106;
|
IPR036291;IPR051687;IPR020904;IPR002347;
|
7LG9;7LGB;
|
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
|
chsB1 Rv3502c
| false |
Mycobacterium tuberculosis
| 1,023 |
row_5458
| false | null |
27,000 |
P9WP21
|
MSTVTGAAGIGLATLAADGSVLDTWFPAPELTESGTSATSRLAVSDVPVELAALIGRDDDRRTETIAVRTVIGSLDDVAADPYDAYLRLHLLSHRLVAPHGLNAGGLFGVLTNVVWTNHGPCAIDGFEAVRARLRRRGPVTVYGVDKFPRMVDYVVPTGVRIADADRVRLGAHLAPGTTVMHEGFVNYNAGTLGASMVEGRISAGVVVGDGSDVGGGASIMGTLSGGGTHVISIGKRCLLGANSGLGISLGDDCVVEAGLYVTAGTRVTMPDSNSVKARELSGSSNLLFRRNSVSGAVEVLARDGQGIALNEDLHAN
|
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase (EC 2.3.1.117) (Tetrahydrodipicolinate N-succinyltransferase) (THDP succinyltransferase) (THP succinyltransferase) (Tetrahydropicolinate succinylase)
|
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
| 83,332 | 317 | 32,642 |
3D-structure;Acyltransferase;Amino-acid biosynthesis;Cytoplasm;Diaminopimelate biosynthesis;Lysine biosynthesis;Magnesium;Metal-binding;Reference proteome;Transferase
|
GO:0000287; GO:0005737; GO:0005886; GO:0008666; GO:0009089; GO:0009274; GO:0019877; GO:0031402; GO:0120226
|
Evidence at protein level
| 5 |
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_02122}.
| null | null |
PF14602;PF14789;
|
IPR019875;IPR001451;IPR032784;IPR038361;IPR011004;IPR026586;
|
3FSX;3FSY;
|
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
|
dapD Rv1201c
| false |
Mycobacterium tuberculosis
| 1,024 |
row_23639
| false | null |
81,762 |
P9WIY3
|
MSIQNSSARRRSAGRIVYAAGAVLWRPGSADSEGPVEIAVIHRPRYDDWSLPKGKVDPGETAPVGAVREILEETGHRANLGRRLLTVTYPTDSPFRGVKKVHYWAARSTGGEFTPGSEVDELIWLPVPDAMNKLDYAQDRKVLCRFAKHPADTQTVLVVRHGTAGSKAHFSGDDSKRPLDKRGRAQAEALVPQLLAFGATDVYAADRVRCHQTMEPLAAELNVTIHNEPTLTEESYANNPKRGRHRVLQIVEQVGTPVICTQGKVIPDLITWWCERDGVHPDKSRNRKGSTWVLSLSAGRLVTADHIGGALAANVRA
|
8-oxo-(d)GTP phosphatase (8-oxo-(d)GTPase) (EC 3.6.1.69) (MtuMutT1) (Mutator protein MutT1)
|
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
| 83,332 | 317 | 34,780 |
DNA damage;DNA repair;DNA replication;Hydrolase;Magnesium;Metal-binding;Reference proteome
|
GO:0006260; GO:0006281; GO:0008413; GO:0046872
|
Evidence at protein level
| 4 | null | null | null |
PF00300;PF00293;
|
IPR013078;IPR029033;IPR020476;IPR015797;IPR020084;IPR000086;
| null |
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
|
mutT1 Rv2985
| false |
Mycobacterium tuberculosis
| 1,025 |
row_72209
| false | null |
112,155 |
A1KHE8
|
MCCTSGCALTIRLLGRTEIRRLAKELDFRPRKSLGQNFVHDANTVRRVVAASGVSRSDLVLEVGPGLGSLTLALLDRGATVTAVEIDPLLASRLQQTVAEHSHSEVHRLTVVNRDVLALRREDLAAAPTAVVANLPYNVAVPALLHLLVEFPSIRVVTVMVQAEVAERLAAEPGSKEYGVPSVKLRFFGRVRRCGMVSPTVFWPIPRVYSGLVRIDRYETSPWPTDDAFRRRVFELVDIAFAQRRKTSRNAFVQWAGSGSESANRLLAASIDPARRGETLSIDDFVRLLRRSGGSDEATSTGRDARAPDISGHASAS
|
Ribosomal RNA small subunit methyltransferase A (EC 2.1.1.182) (16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase) (16S rRNA dimethyladenosine transferase) (16S rRNA dimethylase) (S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase)
|
Mycobacterium bovis (strain BCG / Pasteur 1173P2)
| 410,289 | 317 | 34,646 |
Cytoplasm;Methyltransferase;RNA-binding;rRNA processing;S-adenosyl-L-methionine;Transferase
|
GO:0003723; GO:0005829; GO:0052908
|
Inferred from homology
| 3 |
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00607}.
| null | null |
PF00398;
|
IPR001737;IPR023165;IPR020596;IPR020598;IPR011530;IPR029063;
| null |
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype), Mycobacterium tuberculosis variant bovis BCG (no rank)
|
rsmA ksgA BCG_1067
| false |
Mycobacterium tuberculosis
| 1,026 |
row_100620
| false | null |
212,837 |
P9WLP1
|
MSAQQTNLGIVVGVDGSPCSHTAVEWAARDAQMRNVALRVVQVVPPVITAPEGWAFEYSRFQEAQKREIVEHSYLVAQAHQIVEQAHKVALEASSSGRAAQITGEVLHGQIVPTLANISRQVAMVVLGYRGQGAVAGALLGSVSSSLVRHAHGPVAVIPEEPRPARPPHAPVVVGIDGSPTSGLAAEIAFDEASRRGVDLVALHAWSDMGPLDFPRLNWAPIEWRNLEDEQEKMLARRLSGWQDRYPDVVVHKVVVCDRPAPRLLELAQTAQLVVVGSHGRGGFPGMHLGSVSRAVVNSGQAPVIVARIPQDPAVPA
|
Universal stress protein Rv1996 (USP Rv1996)
|
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
| 83,332 | 317 | 33,880 |
ATP-binding;Isopeptide bond;Nucleotide-binding;Reference proteome;Ubl conjugation
|
GO:0005524; GO:0005886; GO:0009274
|
Evidence at protein level
| 3 | null | null | null |
PF00582;
|
IPR014729;IPR006015;IPR006016;
| null |
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
|
Rv1996 MTCY39.23c
| false |
Mycobacterium tuberculosis
| 1,027 |
row_199041
| false | null |
544,692 |
P64854
|
MTESKAPAVVHPPSMLRGDIDDPKLAAALRTLELTVKQKLDGVLHGDHLGLIPGPGSEPGESRLYQPGDDVRRMDWAVTARTTHPHVRQMIADRELETWLVVDMSASLDFGTACCEKRDLAVAAAAAITFLNSGGGNRLGALIANGAAMTRVPARTGRQHQHTMLRTIATMPQAPAGVRGDLAVAIDALRRPERRRGMAVIISDFLGPINWMRPLRAIAARHEVLAIEVLDPRDVELPDVGDVVLQDAESGVVREFSIDPALRDDFARAAAAHRADVARTIRGCGAPLLSLRTDRDWLADIVRFVASRRRGALAGHQ
|
Uncharacterized protein Mb1516
|
Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
| 233,413 | 317 | 34,333 |
Reference proteome
| null |
Predicted
| 1 | null | null | null |
PF01882;
|
IPR002881;IPR036465;
| null |
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype)
|
BQ2027_MB1516
| false |
Mycobacterium tuberculosis
| 1,028 |
row_524935
| false | null |
81,833 |
P9WMB5
|
MIAGLKGLKLPKDPRSSVTRTATDWAYAAGWMAVRALPEFAVRNAFDTGARYFARHGGPEQLRKNLARVLGVPPAAVPDPLMCASLESYGRYWREVFRLPTINHRKLARQLDRVIGGLDHLDAALAAGLGAVLALPHSGNWDMAGMWLVQRHGTFTTVAERLKPESLYQRFIDYRESLGFEVLPLSGGERPPFEVLSERLRNNRVVCLMAERDLTRTGVEVDFFGEPTRMPVGPAKLAVETGAALLPTHCWFEGRGWGFQVYPALDCTSGDVAAITQALADRFAQNIAAHPADWHMLQPQWLADLSESRRAQLRSR
|
Phosphatidylinositol mannoside acyltransferase (PIM acyltransferase) (EC 2.3.1.265)
|
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
| 83,332 | 316 | 35,126 |
Acyltransferase;Cell inner membrane;Cell membrane;Lipid biosynthesis;Lipid metabolism;Membrane;Phospholipid biosynthesis;Phospholipid metabolism;Reference proteome;Transferase;Virulence
|
GO:0005886; GO:0008654; GO:0009247; GO:0016020; GO:0016746; GO:0046488
|
Evidence at protein level
| 4 |
SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000269|PubMed:12851411}; Peripheral membrane protein {ECO:0000250|UniProtKB:A0QWG5}; Cytoplasmic side {ECO:0000250|UniProtKB:A0QWG5}. Note=Permanently associated with the membrane. {ECO:0000250|UniProtKB:A0QWG5}.
| null | null |
PF03279;
|
IPR004960;
| null |
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
|
patA Rv2611c
| false |
Mycobacterium tuberculosis
| 1,029 |
row_72279
| false | null |
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