Unnamed: 0
int64 2
562k
| Entry
stringlengths 6
10
| Sequence
stringlengths 11
999
| Protein names
stringlengths 5
558
| Organism
stringclasses 392
values | Organism (ID)
int64 595
2.89M
| Length
int64 11
999
| Mass
int64 1.06k
118k
| Keywords
stringlengths 4
380
⌀ | Gene Ontology IDs
stringlengths 10
754
⌀ | Protein existence
stringclasses 5
values | Annotation
float64 1
5
| Subcellular location [CC]
stringlengths 30
2.26k
⌀ | Signal peptide
stringclasses 677
values | Transmembrane
stringlengths 32
2.52k
⌀ | Pfam
stringlengths 8
72
⌀ | InterPro
stringlengths 10
180
⌀ | PDB
stringlengths 5
2.65k
⌀ | Taxonomic lineage
stringclasses 178
values | Gene Names
stringlengths 2
299
⌀ | Toxin
bool 2
classes | species
stringclasses 111
values | cdhit_cluster
int64 0
4.65k
| cdhit_rep
stringlengths 5
10
| cdhit_rep_is_ref
bool 1
class | cdhit_pct_id
float64 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
3,980 |
P34075
|
KICYNQPSSQHPTTKACPGEKNCYRKQWSDHRGTIIERGCGCPTVKPGVKLHCCTTEKCNN
|
Short neurotoxin 1
|
Naja annulata annulata (Banded water cobra) (Boulengerina annulata annulata)
| 8,610 | 61 | 6,837 |
Acetylcholine receptor inhibiting toxin;Direct protein sequencing;Disulfide bond;Ion channel impairing toxin;Neurotoxin;Postsynaptic neurotoxin;Secreted;Toxin
|
GO:0005576; GO:0030550; GO:0090729; GO:0099106
|
Evidence at protein level
| 3 |
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:1814007}.
| null | null |
PF21947;
|
IPR003571;IPR045860;IPR018354;IPR054131;
| null |
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Elapidae (family), Elapinae (subfamily), Naja (genus), Naja annulata (species)
| null | true |
Naja annulata
| 1 |
row_3823
| false | null |
4,154 |
P68407
|
MKFLVNVALVFMVVYISFIYAAPEPEPAPEAEAEADAEADPEAGIGAVLKVLTTGLPALISWIKRKRQQG
|
Melittin (MEL) (MLT)
|
Apis cerana cerana (Oriental honeybee)
| 94,128 | 70 | 7,543 |
Allergen;Amidation;Antimicrobial;Cytolysis;Formylation;Hemolysis;Ion transport;Membrane;Porin;Reference proteome;Secreted;Signal;Target cell membrane;Target membrane;Toxin;Transmembrane;Transport
|
GO:0004860; GO:0005576; GO:0006811; GO:0015288; GO:0031640; GO:0044218; GO:0046930; GO:0090729
|
Inferred from homology
| 3 |
SUBCELLULAR LOCATION: Secreted {ECO:0000305|Ref.1}. Target cell membrane {ECO:0000250|UniProtKB:P01501}. Note=Alpha-helical peptides form toroidal pores in the prey. {ECO:0000250|UniProtKB:P01501}.
|
SIGNAL 1..21; /evidence="ECO:0000250"
| null |
PF01372;
|
IPR002116;
| null |
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Protostomia (clade), Ecdysozoa (clade), Panarthropoda (clade), Arthropoda (phylum), Mandibulata (clade), Pancrustacea (clade), Hexapoda (subphylum), Insecta (class), Dicondylia (clade), Pterygota (subclass), Neoptera (infraclass), Endopterygota (cohort), Hymenoptera (order), Apocrita (suborder), Aculeata (infraorder), Apoidea (superfamily), Anthophila (clade), Apidae (family), Apinae (subfamily), Apini (tribe), Apis (genus), Apis cerana (species)
|
MELT
| true |
Apis cerana
| 0 |
row_3989
| false | null |
7,232 |
Q6H2Z4
|
MISMLRCTFFFVSVILITSYFVTPTMSIKCNRKRHVIKPHICRKICGKNG
|
Mast cell degranulating peptide
|
Apis cerana cerana (Oriental honeybee)
| 94,128 | 50 | 5,820 |
Amidation;Disulfide bond;Formylation;Ion channel impairing toxin;Mast cell degranulation;Neurotoxin;Potassium channel impairing toxin;Secreted;Signal;Toxin
|
GO:0005576; GO:0015459; GO:0090729
|
Evidence at transcript level
| 2 |
SUBCELLULAR LOCATION: Secreted.
|
SIGNAL 1..27; /evidence="ECO:0000255"
| null |
PF17454;
|
IPR035361;
| null |
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Protostomia (clade), Ecdysozoa (clade), Panarthropoda (clade), Arthropoda (phylum), Mandibulata (clade), Pancrustacea (clade), Hexapoda (subphylum), Insecta (class), Dicondylia (clade), Pterygota (subclass), Neoptera (infraclass), Endopterygota (cohort), Hymenoptera (order), Apocrita (suborder), Aculeata (infraorder), Apoidea (superfamily), Anthophila (clade), Apidae (family), Apinae (subfamily), Apini (tribe), Apis (genus), Apis cerana (species)
| null | true |
Apis cerana
| 1 |
row_6953
| false | null |
7,327 |
Q86QT2
|
MISMLRCISLFLSVILITGYFVTPVMSCNCKAPETALCARRCQQHG
|
Apamin
|
Apis cerana cerana (Oriental honeybee)
| 94,128 | 46 | 5,107 |
Amidation;Calcium-activated potassium channel impairing toxin;Disulfide bond;Ion channel impairing toxin;Neurotoxin;Potassium channel impairing toxin;Reference proteome;Secreted;Signal;Toxin
|
GO:0005576; GO:0015459; GO:0090729
|
Inferred from homology
| 2 |
SUBCELLULAR LOCATION: Secreted {ECO:0000250|UniProtKB:P01500}.
|
SIGNAL 1..27; /evidence="ECO:0000255"
| null |
PF17454;
|
IPR035361;
| null |
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Protostomia (clade), Ecdysozoa (clade), Panarthropoda (clade), Arthropoda (phylum), Mandibulata (clade), Pancrustacea (clade), Hexapoda (subphylum), Insecta (class), Dicondylia (clade), Pterygota (subclass), Neoptera (infraclass), Endopterygota (cohort), Hymenoptera (order), Apocrita (suborder), Aculeata (infraorder), Apoidea (superfamily), Anthophila (clade), Apidae (family), Apinae (subfamily), Apini (tribe), Apis (genus), Apis cerana (species)
| null | true |
Apis cerana
| 2 |
row_7046
| false | null |
4,156 |
P68409
|
MKFLVNVALVFMVVYISFIYAAPEPEPAPEAEAEADAEADPEAGIGAVLKVLTTGLPALISWIKRKRQQG
|
Melittin (MEL) (MLT)
|
Vespa velutina nigrithorax (Hornet)
| 202,809 | 70 | 7,543 |
Allergen;Amidation;Antimicrobial;Cytolysis;Formylation;Hemolysis;Ion transport;Membrane;Porin;Secreted;Signal;Target cell membrane;Target membrane;Toxin;Transmembrane;Transport
|
GO:0004860; GO:0005576; GO:0006811; GO:0015288; GO:0031640; GO:0044218; GO:0046930; GO:0090729
|
Inferred from homology
| 3 |
SUBCELLULAR LOCATION: Secreted {ECO:0000305|PubMed:12939801}. Target cell membrane {ECO:0000250|UniProtKB:P01501}. Note=Alpha-helical peptides form toroidal pores in the prey. {ECO:0000250|UniProtKB:P01501}.
|
SIGNAL 1..21; /evidence="ECO:0000250"
| null |
PF01372;
|
IPR002116;
| null |
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Protostomia (clade), Ecdysozoa (clade), Panarthropoda (clade), Arthropoda (phylum), Mandibulata (clade), Pancrustacea (clade), Hexapoda (subphylum), Insecta (class), Dicondylia (clade), Pterygota (subclass), Neoptera (infraclass), Endopterygota (cohort), Hymenoptera (order), Apocrita (suborder), Aculeata (infraorder), Vespoidea (superfamily), Vespidae (family), Vespinae (subfamily), Vespa (genus), Vespa velutina (species)
|
MELT
| true |
Vespa velutina
| 0 |
row_3991
| false | null |
4,953 |
S4S3F6
|
MKNTILILFTAFIALLGFFGMSAEALADPVADPLAGPNAEADPEAINWKGIAAMAKKLLG
|
Mastoparan-V (MP-V)
|
Vespa velutina flavitarsus (Asian hornet)
| 1,075,777 | 60 | 6,231 |
Amidation;Antibiotic;Antimicrobial;G-protein coupled receptor impairing toxin;Immunity;Innate immunity;Mast cell degranulation;Membrane;Repeat;Secreted;Signal;Target cell membrane;Target membrane;Toxin
|
GO:0005576; GO:0016020; GO:0042742; GO:0044218; GO:0045087; GO:0090729
|
Evidence at protein level
| 3 |
SUBCELLULAR LOCATION: Secreted {ECO:0000305|PubMed:21884742}. Target cell membrane {ECO:0000305}. Note=Assumes an amphipathic alpha-helical conformation in a membrane-like environment. {ECO:0000305|PubMed:21884742}.
|
SIGNAL 1..27; /evidence="ECO:0000255"
| null |
PF08249;
|
IPR013213;
| null |
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Protostomia (clade), Ecdysozoa (clade), Panarthropoda (clade), Arthropoda (phylum), Mandibulata (clade), Pancrustacea (clade), Hexapoda (subphylum), Insecta (class), Dicondylia (clade), Pterygota (subclass), Neoptera (infraclass), Endopterygota (cohort), Hymenoptera (order), Apocrita (suborder), Aculeata (infraorder), Vespoidea (superfamily), Vespidae (family), Vespinae (subfamily), Vespa (genus), Vespa velutina (species)
| null | true |
Vespa velutina
| 1 |
row_4720
| false | null |
4,176 |
P69053
|
MQNNNPCGLDGFAFLEFSGPDRNKLHQQFSEMGFQAVAHHKNQDITLFKQGEIQFIVNAASHCQAEAHASTHGPGACAMGFKVKDAKAAFQHAIAHGGIAFQDAPHANHGLPAIQAIGGSVIYFVDEEHQPFSHEWNITSSEPVVGNGLTAIDHLTHNVYRGNMDKWASFYASIFNFQEIRFFNIKGKMTGLVSRALGSPCGKIKIPLNESKDDLSQIEEFLHEYHGEGIQHIALNTNDIYKTVNGLRKQGVKFLDVPDTYYEMINDRLPWHKEPLNQLHAEKILIDGEADPKDGLLLQIFTENIFGPVFFEIIQRKGNQGFGEGNFQALFEAIERDQVRRGTLKELT
|
4-hydroxyphenylpyruvate dioxygenase (4HPPD) (HPD) (HPPDase) (EC 1.13.11.27) (Legiolysin)
|
Legionella pneumophila (strain Corby)
| 400,673 | 348 | 38,927 |
Cytolysis;Dioxygenase;Hemolysis;Iron;Metal-binding;Oxidoreductase;Repeat;Toxin;Virulence
|
GO:0003868; GO:0006572; GO:0031640; GO:0046872; GO:0090729
|
Inferred from homology
| 3 | null | null | null |
PF00903;PF14696;
|
IPR005956;IPR041735;IPR041736;IPR029068;IPR004360;IPR037523;
| null |
cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Gammaproteobacteria (class), Legionellales (order), Legionellaceae (family), Legionella (genus), Legionella pneumophila (species)
|
lly LPC_1747
| true |
Legionella pneumophila
| 0 |
row_4011
| false | null |
4,330 |
P84707
|
MGFRVLVLIVMVTTSALPFTFSEESGRSPFRPALRSEEAQALRHGLTLLLARRADGQTPDMHQPEMRRPEMRRPEVRRPEVRQPEFAESPVGQKRWDAYDCIQFCMRPEMRHTYAQCLSICT
|
Conotoxin flf14c (Conotoxin flf14.1)
|
Conus anabathrum floridanus (Florida cone) (Conus floridanus floridensis)
| 1,520,082 | 122 | 14,192 |
Cleavage on pair of basic residues;Direct protein sequencing;Disulfide bond;Secreted;Signal;Toxin
|
GO:0005576; GO:0090729
|
Evidence at protein level
| 3 |
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:16331958}.
|
SIGNAL 1..22; /evidence="ECO:0000255"
| null | null | null | null |
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Protostomia (clade), Spiralia (clade), Lophotrochozoa (clade), Mollusca (phylum), Gastropoda (class), Caenogastropoda (subclass), Neogastropoda (order), Conoidea (superfamily), Conidae (family), Conus (genus), Dauciconus (subgenus), Conus anabathrum (species)
| null | true |
Conus anabathrum
| 0 |
row_4163
| false | null |
5,095 |
A0A3G1VU73
|
MGFRVLVLIVMVTTSALPFTFSEESGRSPFRPALRSEEAQALRHGLTLLLARRADGQPSDMRQPEMRRPEMRRPEVRRPEVRQPEFAESPVGQKRWDVNDCIHFCLIGVVGRSYTECHTMCT
|
Conotoxin flf14.2
|
Conus anabathrum floridanus (Florida cone) (Conus floridanus floridensis)
| 1,520,082 | 122 | 14,015 |
Cleavage on pair of basic residues;Disulfide bond;Secreted;Signal;Toxin
|
GO:0005576; GO:0090729
|
Evidence at transcript level
| 2 |
SUBCELLULAR LOCATION: Secreted {ECO:0000305|PubMed:30040981}.
|
SIGNAL 1..22; /evidence="ECO:0000255"
| null | null | null | null |
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Protostomia (clade), Spiralia (clade), Lophotrochozoa (clade), Mollusca (phylum), Gastropoda (class), Caenogastropoda (subclass), Neogastropoda (order), Conoidea (superfamily), Conidae (family), Conus (genus), Dauciconus (subgenus), Conus anabathrum (species)
| null | true |
Conus anabathrum
| 1 |
row_4862
| false | null |
4,328 |
P84705
|
WDVNDCIHFCLIGVVERSYTECHTMCT
|
Conotoxin flf14a
|
Conus anabathrum floridanus (Florida cone) (Conus floridanus floridensis)
| 1,520,082 | 27 | 3,176 |
Direct protein sequencing;Disulfide bond;Secreted;Toxin
|
GO:0005576; GO:0090729
|
Evidence at protein level
| 3 |
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:16331958}.
| null | null | null | null | null |
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Protostomia (clade), Spiralia (clade), Lophotrochozoa (clade), Mollusca (phylum), Gastropoda (class), Caenogastropoda (subclass), Neogastropoda (order), Conoidea (superfamily), Conidae (family), Conus (genus), Dauciconus (subgenus), Conus anabathrum (species)
| null | true |
Conus anabathrum
| 2 |
row_4161
| false | null |
4,329 |
P84706
|
WDVNDCIHFCLIGVVGRSYTECHTMCT
|
Conotoxin flf14b
|
Conus anabathrum floridanus (Florida cone) (Conus floridanus floridensis)
| 1,520,082 | 27 | 3,104 |
Direct protein sequencing;Disulfide bond;Secreted;Toxin
|
GO:0005576; GO:0090729
|
Evidence at protein level
| 3 |
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:16331958}.
| null | null | null | null | null |
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Protostomia (clade), Spiralia (clade), Lophotrochozoa (clade), Mollusca (phylum), Gastropoda (class), Caenogastropoda (subclass), Neogastropoda (order), Conoidea (superfamily), Conidae (family), Conus (genus), Dauciconus (subgenus), Conus anabathrum (species)
| null | true |
Conus anabathrum
| 3 |
row_4162
| false | null |
6,921 |
P85219
|
MSGIVEAISNAVKSGLDHDWVNMGTSIADVVAKGADFIAGFFS
|
Hemolysin H1C
|
Staphylococcus cohnii subsp. cohnii
| 74,704 | 43 | 4,429 |
Cytolysis;Direct protein sequencing;Formylation;Hemolysis;Secreted;Toxin;Virulence
|
GO:0005576; GO:0031640; GO:0090729
|
Evidence at protein level
| 2 |
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:18752624}.
| null | null |
PF05480;
|
IPR008846;
| null |
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Bacillota (phylum), Bacilli (class), Bacillales (order), Staphylococcaceae (family), Staphylococcus (genus), Staphylococcus cohnii species complex (no rank), Staphylococcus cohnii (species)
| null | true |
Staphylococcus cohnii
| 0 |
row_6651
| false | null |
6,922 |
P85221
|
MSDFVNAISEAVKAGLSADWVTMGTSIADALAKGADFILGFFN
|
Hemolysin H3C
|
Staphylococcus cohnii subsp. cohnii
| 74,704 | 43 | 4,453 |
Cytolysis;Direct protein sequencing;Formylation;Hemolysis;Secreted;Toxin;Virulence
|
GO:0005576; GO:0031640; GO:0090729
|
Evidence at protein level
| 2 |
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:18752624}.
| null | null |
PF05480;
|
IPR008846;
| null |
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Bacillota (phylum), Bacilli (class), Bacillales (order), Staphylococcaceae (family), Staphylococcus (genus), Staphylococcus cohnii species complex (no rank), Staphylococcus cohnii (species)
| null | true |
Staphylococcus cohnii
| 1 |
row_6652
| false | null |
4,376 |
P85220
|
MDFIIDIIKKIVGLFTGK
|
Hemolysin H2C
|
Staphylococcus cohnii subsp. cohnii
| 74,704 | 18 | 2,052 |
Cytolysis;Direct protein sequencing;Formylation;Hemolysis;Secreted;Toxin;Virulence
|
GO:0005576; GO:0031640; GO:0090729
|
Evidence at protein level
| 3 |
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:18752624}.
| null | null | null | null | null |
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Bacillota (phylum), Bacilli (class), Bacillales (order), Staphylococcaceae (family), Staphylococcus (genus), Staphylococcus cohnii species complex (no rank), Staphylococcus cohnii (species)
| null | true |
Staphylococcus cohnii
| 2 |
row_4196
| false | null |
4,543 |
Q32GM1
|
MKIIIFRVLTFFFVIFSVNVVAKEFTLDFSTAKTYVDSLNVIRSAIGTPLQTISSGGTSLLMIDSGTGDNLFAVDVRGIDPEEGRFNNLRLIVERNNLYVTGFVNRTNNVFYRFADFSHVTFPGTTAVTLSGDSSYTTLQRVAGISRTGMQINRHSLTTSYLDLMSHSGTSLTQSVARAMLRFVTVTAEALRFRQIQRGFRTTLDDLSGRSYVMTAEDVDLTLNWGRLSSVLPDYHGQDSVRVGRISFGSINAILGSVALILNCHHHASRVARMASDEFPSMCPADGRVRGITHNKILWDSSTLGAILMRRTISS
|
Shiga toxin subunit A (EC 3.2.2.22)
|
Shigella dysenteriae serotype 1 (strain Sd197)
| 300,267 | 315 | 34,814 |
Disulfide bond;Hydrolase;Protein synthesis inhibitor;Reference proteome;Signal;Toxin;Virulence
|
GO:0017148; GO:0030598; GO:0090729; GO:0141130
|
Inferred from homology
| 3 | null |
SIGNAL 1..22; /evidence="ECO:0000255"
| null |
PF00161;
|
IPR036041;IPR001574;IPR017988;IPR016138;IPR016139;IPR016331;
| null |
cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Gammaproteobacteria (class), Enterobacterales (order), Enterobacteriaceae (family), Shigella (genus), Shigella dysenteriae (species)
|
stxA SDY_1389
| true |
Shigella dysenteriae
| 0 |
row_4344
| false | null |
7,057 |
Q32GM0
|
MKKTLLIAASLSFFSASALATPDCVTGKVEYTKYNDDDTFTVKVGDKELFTNRWNLQSLLLSAQITGMTVTIKTNACHNGGGFSEVIFR
|
Shiga toxin subunit B
|
Shigella dysenteriae serotype 1 (strain Sd197)
| 300,267 | 89 | 9,743 |
Disulfide bond;Reference proteome;Signal;Toxin;Virulence
|
GO:0005576; GO:0019836; GO:0044177; GO:0090729
|
Inferred from homology
| 2 | null |
SIGNAL 1..20; /evidence="ECO:0000255"
| null |
PF02258;
|
IPR008992;IPR003189;
| null |
cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Gammaproteobacteria (class), Enterobacterales (order), Enterobacteriaceae (family), Shigella (genus), Shigella dysenteriae (species)
|
stxB SDY_1390
| true |
Shigella dysenteriae
| 1 |
row_6779
| false | null |
4,588 |
Q45UF1
|
MEGTSESPVLDEFEVNNNDYDNDFISRFSQNPLNAFSLFTDGNLQEYFMNNSLEKIVIHVVLIVISLCGIKAQTSKIIYVVRLLFWKIYNVINNLVNKVINREKIINHQVVDNRFREFEERFRLLLLQHDKNIAKQDDIVQYNKLDNFAESIKSEFNLKVAEMERRFQELKWRCDMIANKAMNTIVLANTVDSNNKDEKIVFDEGSVVQYNRE
|
Non-structural glycoprotein 4 (NSP4) (NCVP5) (NS28)
|
Rotavirus X (strain RVX/Human/China/NADRV-J19/1997/GXP[X]) (RV ADRV-N) (Rotavirus (isolate novel adult diarrhea rotavirus-J19))
| 335,103 | 213 | 25,111 |
Activation of host autophagy by virus;Enterotoxin;Glycoprotein;Host endoplasmic reticulum;Host membrane;Host-virus interaction;Ion channel;Ion transport;Membrane;Reference proteome;Secreted;Signal-anchor;Toxin;Transmembrane;Transmembrane helix;Transport;Viral ion channel;Virulence
|
GO:0005576; GO:0015267; GO:0016020; GO:0016032; GO:0034220; GO:0039520; GO:0044155; GO:0044169; GO:0090729
|
Inferred from homology
| 3 |
SUBCELLULAR LOCATION: Host rough endoplasmic reticulum membrane {ECO:0000255|HAMAP-Rule:MF_04091}; Single-pass type III membrane protein {ECO:0000255|HAMAP-Rule:MF_04091}. Host membrane, host caveola {ECO:0000255|HAMAP-Rule:MF_04091}; Single-pass type III membrane protein {ECO:0000255|HAMAP-Rule:MF_04091}. Secreted {ECO:0000255|HAMAP-Rule:MF_04091}. Note=NSP4 also localizes in vesicular structures which contain autophagosomal markers and associate with viroplasms in virus-infected cells. Additionally, a soluble form of glycosylated NSP4 is secreted despite retention of its transmembrane domain. {ECO:0000255|HAMAP-Rule:MF_04091}.
| null |
TRANSMEM 52..74; /note="Helical; Signal-anchor for type III membrane protein"; /evidence="ECO:0000255|HAMAP-Rule:MF_04091"
| null |
IPR002107;
| null |
Viruses (no rank), Riboviria (realm), Orthornavirae (kingdom), Duplornaviricota (phylum), Resentoviricetes (class), Reovirales (order), Sedoreoviridae (family), Rotavirus (genus), Rotavirus H (species)
| null | true |
Rotavirus H
| 0 |
row_4370
| false | null |
4,606 |
Q54114
|
MKDMSNKKIFKKYSRVAGLLTAALIVGNLVTANADSNKQNTANTETTTTNEQPKPESSELTTEKAGQKMDDMLNSNDMIKLAPKEMPLESAEKEEKKSEDNKKSEEDHTEEINDKIYSLNYNELEVLAKNGETIENFVPKEGVKKADKFIVIERKKKNINTTPVDISIIDSVTDRTYPAALQLANKGFTENKPDAVVTKRNPQKIHIDLPGMGDKATVEVNDPTYANVSTAIDNLVNQWHDNYSGGNTLPARTQYTESMVYSKSQIEAALNVNSKILDGTLGIDFKSISKGEKKVMIAAYKQIFYTVSANLPNNPADVFDKSVTLKELQRKGVSNEAPPLFVSNVAYGRTVFVKLETSSKSNDVEAAFSAALKGTDVKTNGKYSDILENSSFTAVVLGGDAAEHNKVVTKDFDVIRNVIKDNATFSRKNPAYPISYTSVFLKNNKIAGVNNRSEYVETTSTEYTSGKINLSHQGAYVAQYEILWDEINYDDKGKEVITKRRWDNNWYSKTSPFSTVIPLGANSRNIRIMARECTGLAWEWWRKVIDERDVKLSKEINVNISGSTLSPYGSITYK
|
Streptolysin O (SLO) (Thiol-activated cytolysin)
|
Streptococcus dysgalactiae subsp. equisimilis (Streptococcus equisimilis)
| 119,602 | 574 | 63,992 |
Cytolysis;Hemolysis;Host cell membrane;Host membrane;Lipid-binding;Membrane;Secreted;Signal;Toxin;Transmembrane;Transmembrane beta strand;Virulence
|
GO:0005576; GO:0015485; GO:0016020; GO:0020002; GO:0031640; GO:0090729
|
Inferred from homology
| 3 |
SUBCELLULAR LOCATION: Secreted {ECO:0000250|UniProtKB:P0C2J9}. Host cell membrane {ECO:0000250|UniProtKB:P13128}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q04IN8}. Note=Probably secreted as soluble protein by the accessory Sec system (By similarity). It then inserts into the host cell membrane and forms pores formed by transmembrane beta-strands (By similarity). {ECO:0000250|UniProtKB:P0C2J9, ECO:0000250|UniProtKB:Q04IN8}.
|
SIGNAL 1..36; /evidence="ECO:0000250"
|
TRANSMEM 263..276; /note="Beta stranded"; /evidence="ECO:0000250|UniProtKB:Q04IN8"; TRANSMEM 283..292; /note="Beta stranded"; /evidence="ECO:0000250|UniProtKB:Q04IN8"; TRANSMEM 361..370; /note="Beta stranded"; /evidence="ECO:0000250|UniProtKB:Q04IN8"; TRANSMEM 378..390; /note="Beta stranded"; /evidence="ECO:0000250|UniProtKB:Q04IN8"
|
PF17440;PF01289;
|
IPR035390;IPR038700;IPR001869;IPR036363;IPR036359;
| null |
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Bacillota (phylum), Bacilli (class), Lactobacillales (order), Streptococcaceae (family), Streptococcus (genus), Streptococcus dysgalactiae group (no rank), Streptococcus dysgalactiae (species)
|
slo
| true |
Streptococcus dysgalactiae
| 0 |
row_4384
| false | null |
4,628 |
Q5QGZ2
|
MAESSDMQELFVQATYEEILKLASSVNHEQIRETISSSSPQKILTGTMLTLGALLTTLIVKKKGTKFLTTKVQSNVAYLAEMVVWKANQTVKTICDEVLHQRKVIEKLQCLDKMCSEIEKLRYDMEHFQGMDVTKELIQMCEQKMIDIDSKVKEVERSCDRRIRDYDWKIATLTAHPTQQLPAHIDIINQHIEDDAETQIIQQHMNKQARVKLNSRNRL
|
Non-structural glycoprotein 4 (NSP4) (NCVP5) (NS28)
|
Rotavirus B (isolate RVB/Human/China/ADRV/1982) (RV-B) (Rotavirus B (isolate adult diarrhea rotavirus))
| 10,942 | 219 | 25,347 |
Activation of host autophagy by virus;Enterotoxin;Glycoprotein;Host endoplasmic reticulum;Host membrane;Host-virus interaction;Ion channel;Ion transport;Membrane;Secreted;Signal-anchor;Toxin;Transmembrane;Transmembrane helix;Transport;Viral ion channel;Virulence
|
GO:0005576; GO:0015267; GO:0016020; GO:0016032; GO:0034220; GO:0039520; GO:0044155; GO:0044169; GO:0090729
|
Inferred from homology
| 3 |
SUBCELLULAR LOCATION: Host rough endoplasmic reticulum membrane {ECO:0000255|HAMAP-Rule:MF_04091}; Single-pass type III membrane protein {ECO:0000255|HAMAP-Rule:MF_04091}. Host membrane, host caveola {ECO:0000255|HAMAP-Rule:MF_04091}; Single-pass type III membrane protein {ECO:0000255|HAMAP-Rule:MF_04091}. Secreted {ECO:0000255|HAMAP-Rule:MF_04091}. Note=NSP4 also localizes in vesicular structures which contain autophagosomal markers and associate with viroplasms in virus-infected cells. Additionally, a soluble form of glycosylated NSP4 is secreted despite retention of its transmembrane domain. {ECO:0000255|HAMAP-Rule:MF_04091}.
| null |
TRANSMEM 48..74; /note="Helical; Signal-anchor for type III membrane protein"; /evidence="ECO:0000255|HAMAP-Rule:MF_04091"
| null |
IPR002107;
| null |
Viruses (no rank), Riboviria (realm), Orthornavirae (kingdom), Duplornaviricota (phylum), Resentoviricetes (class), Reovirales (order), Sedoreoviridae (family), Rotavirus (genus), Rotavirus B (species)
| null | true |
Rotavirus B
| 0 |
row_4405
| false | null |
4,736 |
Q813X6
|
MSLNMYLGEVQGQTQSMNAVCNATIQGMEQVIQSIDAFAIDTVLQGQTYSSAKSFFVQTFRPLAQGIIYLCEELIRQNDAFPSQFQSQVASTDVIEQEILEQIREIDRMKASMEAISQAMPIPGMDAMANLFTVMRKKLQEKLDHLYQFNQTSSNNYSTALQLAASIAAGLAEVQSGKGFSPASGTFSTQGLNMEWTTSIQAITEERARQAANSIEEGEMCGKLPEKSTGEKIWDGIVEGTGQAVSDTIDGIKALGDWETWENMGNAALHPIDTLSTMYNTLSDSFINDVINGDAESRAKWGSYALTQVGLGLIGDKGLSKASKLGQAGKVTKLAKNKIPQAVSHITSNLQMGDRFAFAGGNSLRFRFDTPDFKKAEEKLSTYQFARGESNYGGSNFVNENHRSSLSNREIISNLQHTEKFRPNTLKHILEGEINWRGDAMGYHTEVLENTPGKIISGTEEILNDQGIYKARVEVNGTPKTGNRGFSTFFPKDWSPQKIVDNINEAYNNRTYEFGNTYSGIGSEGIRISMYIDGNGKIISAFPAE
|
Toxin BC_0920 (Ribonuclease BC_0920) (RNase BC_0920) (EC 3.1.-.-)
|
Bacillus cereus (strain ATCC 14579 / DSM 31 / CCUG 7414 / JCM 2152 / NBRC 15305 / NCIMB 9373 / NCTC 2599 / NRRL B-3711)
| 226,900 | 545 | 59,954 |
Hydrolase;Nuclease;Reference proteome;Secreted;Toxin
|
GO:0004519; GO:0005576; GO:0090729
|
Evidence at protein level
| 3 |
SUBCELLULAR LOCATION: Secreted {ECO:0000305}. Note=Delivery to target cells requires a type VII secretion system (T7SS). {ECO:0000305}.
| null | null |
PF14436;PF04740;
|
IPR051768;IPR029501;IPR006829;
| null |
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Bacillota (phylum), Bacilli (class), Bacillales (order), Bacillaceae (family), Bacillus (genus), Bacillus cereus group (no rank), Bacillus cereus (species)
|
BC_0920
| true |
Bacillus cereus
| 0 |
row_4512
| false | null |
4,737 |
Q82055
|
MDFINQTLFSKYTESNVDTIPYLLGLILALTNGSRILRFINSFIIICKHIVTTSKSAIDKMRKINNSEHNTKNAHEEYEEVMKQIREMRIHMTALFNSLHDDNVKWRMSESIRREKKHEMKMSDNRNEFKHSHNDTNICEKSGLETEVCL
|
Non-structural glycoprotein 4 (NSP4) (NCVP5) (NS28)
|
Rotavirus C (isolate RVC/Human/United Kingdom/Bristol/1989) (RV-C)
| 31,567 | 150 | 17,705 |
Activation of host autophagy by virus;Enterotoxin;Glycoprotein;Host endoplasmic reticulum;Host membrane;Host-virus interaction;Ion channel;Ion transport;Membrane;Reference proteome;Secreted;Signal-anchor;Toxin;Transmembrane;Transmembrane helix;Transport;Viral ion channel;Virulence
|
GO:0005576; GO:0015267; GO:0016020; GO:0016032; GO:0034220; GO:0039520; GO:0044155; GO:0044169; GO:0090729
|
Inferred from homology
| 3 |
SUBCELLULAR LOCATION: Host rough endoplasmic reticulum membrane {ECO:0000255|HAMAP-Rule:MF_04091}; Single-pass type III membrane protein {ECO:0000255|HAMAP-Rule:MF_04091}. Host membrane, host caveola {ECO:0000255|HAMAP-Rule:MF_04091}; Single-pass type III membrane protein {ECO:0000255|HAMAP-Rule:MF_04091}. Secreted {ECO:0000255|HAMAP-Rule:MF_04091}. Note=NSP4 also localizes in vesicular structures which contain autophagosomal markers and associate with viroplasms in virus-infected cells. Additionally, a soluble form of glycosylated NSP4 is secreted despite retention of its transmembrane domain. {ECO:0000255|HAMAP-Rule:MF_04091}.
| null |
TRANSMEM 16..44; /note="Helical; Signal-anchor for type III membrane protein"; /evidence="ECO:0000255|HAMAP-Rule:MF_04091"
| null |
IPR002107;
| null |
Viruses (no rank), Riboviria (realm), Orthornavirae (kingdom), Duplornaviricota (phylum), Resentoviricetes (class), Reovirales (order), Sedoreoviridae (family), Rotavirus (genus), Rotavirus C (species)
| null | true |
Rotavirus C
| 0 |
row_4513
| false | null |
4,944 |
Q9YS17
|
MEFINQTFFSDYSEGKIDTIPYALGIVLALTNGSRILKFINLLISLLRKFIITSKTVIGKFKIENNTSHQNDDIHKEYEEVMKQMREMRVHVTALFDSIHKDNMEWRMSESIRREKKREMKASTAENEVKIHTNDVNICDTSGLETEVCL
|
Non-structural glycoprotein 4 (NSP4) (NCVP5) (NS28)
|
Rotavirus C (strain RVC/Pig/United States/Cowden/1980) (RV-C)
| 10,916 | 150 | 17,489 |
Activation of host autophagy by virus;Enterotoxin;Glycoprotein;Host endoplasmic reticulum;Host membrane;Host-virus interaction;Ion channel;Ion transport;Membrane;Secreted;Signal-anchor;Toxin;Transmembrane;Transmembrane helix;Transport;Viral ion channel;Virulence
|
GO:0005576; GO:0015267; GO:0016020; GO:0016032; GO:0034220; GO:0039520; GO:0044155; GO:0044169; GO:0090729
|
Evidence at transcript level
| 3 |
SUBCELLULAR LOCATION: Host rough endoplasmic reticulum membrane {ECO:0000255|HAMAP-Rule:MF_04091}; Single-pass type III membrane protein {ECO:0000255|HAMAP-Rule:MF_04091}. Host membrane, host caveola {ECO:0000255|HAMAP-Rule:MF_04091}; Single-pass type III membrane protein {ECO:0000255|HAMAP-Rule:MF_04091}. Secreted {ECO:0000255|HAMAP-Rule:MF_04091}. Note=NSP4 also localizes in vesicular structures which contain autophagosomal markers and associate with viroplasms in virus-infected cells. Additionally, a soluble form of glycosylated NSP4 is secreted despite retention of its transmembrane domain. {ECO:0000255|HAMAP-Rule:MF_04091}.
| null |
TRANSMEM 16..30; /note="Helical; Signal-anchor for type III membrane protein"; /evidence="ECO:0000255|HAMAP-Rule:MF_04091"
| null |
IPR002107;
| null |
Viruses (no rank), Riboviria (realm), Orthornavirae (kingdom), Duplornaviricota (phylum), Resentoviricetes (class), Reovirales (order), Sedoreoviridae (family), Rotavirus (genus), Rotavirus C (species), Porcine rotavirus C (no rank)
| null | true |
Rotavirus C
| 1 |
row_4715
| false | null |
4,738 |
Q838U8
|
MSQLNKWQKELQALQKANYQETDNQLFNVYRQSLIDIKKRLKVYTENAESLSFSTRLEVERLFSVADEINAILQLNSPKVEKTIKGYSAKQAEQGYYGLWYTLEQSQNIALSMPLINHDYIMNLVNAPVAGKRLSKRLYKYRDELAQNVTNNIITGLFEGKSYAEIARWINEETEASYKQALRIARTEAGRTQSVTTQKGYEEAKELGINIKKKWLATIDKHTRRTHQELDGKEVDVDEEFTIRGHSAKGPRMFGVASEDVNCRCTTIEVVDGISPELRKDNESKEMSEFKSYDEWYADRIRQNESKPKPNFTELDFFGQSDLQDDSDKWVAGLKPEQVNAMKDYTSDAFAKMNKILRNEKYNPREKPYLVNIIQNLDDAISKFKLKHDIITYRGVSANEYDAILNGNVFKEFKSTSINKKVAEDFLNFTSANKDGRVVKFLIPKGTQGAYIGTNSSMKKESEFLLNRNLKYTVEIVDNILEVTILG
|
NAD(+)--arginine ADP-ribosyltransferase EFV (EC 2.4.2.31) (Putative mono(ADP-ribosyl)transferase) (mADPRT) (mART) (Toxin EFV)
|
Enterococcus faecalis (strain ATCC 700802 / V583)
| 226,185 | 487 | 56,055 |
Coiled coil;Glycosyltransferase;NAD;NADP;Nucleotide-binding;Nucleotidyltransferase;Reference proteome;Secreted;Toxin;Transferase;Virulence
|
GO:0000166; GO:0005576; GO:0016779; GO:0090729; GO:0106274
|
Evidence at protein level
| 3 |
SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
| null | null |
PF03496;PF04233;
|
IPR003540;IPR006528;
| null |
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Bacillota (phylum), Bacilli (class), Lactobacillales (order), Enterococcaceae (family), Enterococcus (genus), Enterococcus faecalis (species)
|
EF_0335
| true |
Enterococcus faecalis
| 0 |
row_4514
| false | null |
4,803 |
Q97Y90
|
MAQKSEKENIIGRIANLLAVGFLYSESPTLVDRFANALSKEAVTKVLYDVQRIVQMGIDRSEIATTTITIQGKDYPAQGKDYPAVNVNSSGAKYTVVGYLPTSQDIEDFLRMIEEDVYYARKAGALAMSIANRIKLGSKQSKSEQGGEKK
|
CRISPR type I-A cluster 2/Apern-associated protein Csa5-2 (Probable CRISPR toxin Csa5)
|
Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus)
| 273,057 | 150 | 16,487 |
Antiviral defense;Reference proteome;Toxin
|
GO:0051607; GO:0090729
|
Evidence at protein level
| 3 | null | null | null |
PF09702;
|
IPR010157;
| null |
cellular organisms (no rank), Archaea (domain), Thermoproteati (kingdom), Thermoproteota (phylum), Thermoprotei (class), Sulfolobales (order), Sulfolobaceae (family), Saccharolobus (genus), Saccharolobus solfataricus (species)
|
csa5 SSO1443
| true |
Saccharolobus solfataricus
| 0 |
row_4579
| false | null |
4,902 |
Q9RFY6
|
MRLLFFLLITLLFAACSSTPKVHQPKHSSKTEKDLGIGLSPTPPPNERIPGEKSRAMLMEMEGREIPVRIPDANASKIDKNVSNPISIMSSSGGLLTLWALKPRNWVWGYTPIDSFEFGRAKFWRIISFSNGQVIIKNMQEGTCLQAYGNGVIHDICDSKNQAQLWNLNFFDNQAIQIQSVSAKTCLQTPTVRTTTYYSIYLTKCATSSNLDQQWYITPVALEPEPIFFIK
|
Cytolethal distending toxin subunit A (CDT A)
|
Helicobacter hepaticus (strain ATCC 51449 / 3B1)
| 235,279 | 231 | 26,021 |
Cell outer membrane;Lectin;Lipoprotein;Membrane;Palmitate;Reference proteome;Signal;Toxin;Virulence
|
GO:0009279; GO:0030246; GO:0090729
|
Inferred from homology
| 3 |
SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}.
|
SIGNAL 1..15; /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
| null |
PF03498;
|
IPR015957;IPR003558;IPR035992;
| null |
cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Campylobacterota (phylum), Epsilonproteobacteria (class), Campylobacterales (order), Helicobacteraceae (family), Helicobacter (genus), Helicobacter hepaticus (species)
|
cdtA HH_1446
| true |
Helicobacter hepaticus
| 0 |
row_4676
| false | null |
4,906 |
Q9SBK8
|
MEGKTVILGVIIMSLVMAQNQVEAKICCPRTIDRNIYNACRLTGASMTNCANLSGCKIVSGTTCPPGYTHDILQNYGDAVNEYCKLGCASSVCGALTTLKNSMQVNCEGAVSQCTNACSNFCTKGSAKVVETA
|
Thionin
|
Brassica rapa subsp. pekinensis (Chinese cabbage) (Brassica pekinensis)
| 51,351 | 133 | 13,961 |
Disulfide bond;Plant defense;Secreted;Signal;Toxin
|
GO:0005576; GO:0006952; GO:0090729
|
Evidence at transcript level
| 3 |
SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
|
SIGNAL 1..24; /evidence="ECO:0000255"
| null |
PF00321;
|
IPR001010;IPR036391;
| null |
cellular organisms (no rank), Eukaryota (domain), Viridiplantae (kingdom), Streptophyta (phylum), Streptophytina (subphylum), Embryophyta (clade), Tracheophyta (clade), Euphyllophyta (clade), Spermatophyta (clade), Magnoliopsida (class), Mesangiospermae (clade), eudicotyledons (clade), Gunneridae (clade), Pentapetalae (clade), rosids (clade), malvids (clade), Brassicales (order), Brassicaceae (family), Brassiceae (tribe), Brassica (genus), Brassica campestris (species)
|
THI2
| true |
Brassica campestris
| 0 |
row_4679
| false | null |
5,017 |
A0A067SLB9
|
MFDTNATRLPIWGIGCNPWTAEHVDQTLASGNDIC
|
Alpha-amanitin proprotein 1 [Cleaved into: Alpha-amanitin (Amatoxin) (Gamma-amanitin)]
|
Galerina marginata (strain CBS 339.88)
| 685,588 | 35 | 3,848 |
3D-structure;Hydroxylation;Reference proteome;Thioether bond;Toxin
|
GO:0090729
|
Evidence at protein level
| 2 | null | null | null |
PF24112;
|
IPR027582;
|
5N4B;5N4C;5N4D;5N4E;
|
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Fungi (kingdom), Dikarya (subkingdom), Basidiomycota (phylum), Agaricomycotina (subphylum), Agaricomycetes (class), Agaricomycetidae (subclass), Agaricales (order), Agaricineae (suborder), Strophariaceae (family), Galerina (genus), Galerina marginata (species)
|
AMA1-1 GALMADRAFT_1387421
| true |
Galerina marginata
| 0 |
row_4784
| false | null |
6,020 |
O05961
|
MLKSSKHEDSSSKKNQNNKLIFIVRQLFYLIKHFFSKTKTPDNFFGIIKRLKINSQKMSLDEFNILANLLKLEDKIVEDIMVPRSDIIAIKLTTNLEELSESIKIAVPHTRTLIYDGTLDNVVGFIHIKDLFKALATKQNSPLKRLIRKHIIAAPSMKLLDLLAKMRRERTHIAIVVDEYGGTDGLVTIEDLIEEIVGRIDDEHDQQLDSANFKVINNSTIIANARIEVELLEEIIGEKLKNDDDEFDTIGGLVLTRVSSVPAIGTRIDISENIEIEVTDATPRSLKQVKIRLKNGLNSDNLT
|
Hemolysin C
|
Rickettsia prowazekii (strain Madrid E)
| 272,947 | 303 | 34,322 |
CBS domain;Cytolysis;Hemolysis;Reference proteome;Repeat;Toxin;Virulence
|
GO:0031640; GO:0050660; GO:0090729
|
Evidence at transcript level
| 2 | null | null | null |
PF00571;PF03471;
|
IPR000644;IPR046342;IPR036318;IPR016169;IPR044751;IPR005170;IPR051676;
| null |
cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia prowazekii (species)
|
tlyC RP740
| true |
Rickettsia prowazekii
| 0 |
row_5779
| false | null |
6,718 |
P19247
|
MKKMTLFTLSLLATAVQVGAQEYVPIVEKPIYITSSKIKCVLHTSGDFNATRDWCNAGASIDVRVNVAQMRSVQSATSDGFTPDAKIVRFTVDADKPGTGIHLVNELQQDHSWFQSWANRRTYIGPFASSYDLWVKPVSGYTPKKARDLPQNENKNYQHRDTYGYSIGINGKVGAEVNKDGPKVGGEVSGSFTYNYSKTLVFDTKDYRINNRSSLSDFDISFEREFGECDELRRQELGCYFTAAHWGSGWVFDKTKFNPISYSNFKPNYDVLYEAPVSETGVTDFEMGVKLNYRARFGTVLPSALFSVYGSAGSSTNSSTVKQRIRIDWNHPLFEAEAHVTLQSLSNNDLCLDVYGENGDKTVAGGSVNGWSCHGSWNQVWGLDKEERYRSRVASDRCLTVNADKTLTVEQCGANLAQKWYWEGDKLISRYVDGNNTRYLLNIVGGRNVQVTPENEANQARWKPTLQQVKL
|
Cytolysin
|
Vibrio vulnificus (strain CMCP6)
| 216,895 | 471 | 52,899 |
3D-structure;Cytolysis;Hemolysis;Lectin;Signal;Toxin;Virulence
|
GO:0005576; GO:0030246; GO:0051715; GO:0090729
|
Evidence at protein level
| 2 | null |
SIGNAL 1..20
| null |
PF07968;PF00652;
|
IPR016183;IPR036435;IPR035992;IPR000772;
|
4OWJ;4OWK;4OWL;
|
cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Gammaproteobacteria (class), Vibrionales (order), Vibrionaceae (family), Vibrio (genus), Vibrio vulnificus (species)
|
vvhA VV2_0404
| true |
Vibrio vulnificus
| 0 |
row_6466
| false | null |
6,021 |
O06695
|
MVDAINPLGTDGFEFVEYTAADNTGIEQLKHLFSSLGFAEVAKHRSKEAWLYRQGDINFVVNAQPHSQAEEFAKVHGPSVCGMAFRVQDAASALKHALTNGAEEYKTEIGPMELSIPAVYGIGGSLLYFVDRYGKQSIYDVDFRFYDDAAQRLAKSDVGLYEIDHLTHNVKRGNMDTWAGFYERIGNFREIRYFDIEGKLTGLVSRAMTAPCGKIRIPINESSDDKSQIEEFIREYNGEGIQHIALTTDDIYQTVQTLRDRGMDFMPTPDTYYDKVDSRVEGHKEDVSRLRDLRILIDGAPLKDGILLQIFTQTVIGPVFFEIIQRKGNEGFGEGNFKALFESIEEDQIRRGVLNNA
|
Hemolysin VllY
|
Vibrio vulnificus (strain CMCP6)
| 216,895 | 357 | 40,280 |
Cytolysis;Hemolysis;Iron;Metal-binding;Repeat;Toxin;Virulence
|
GO:0001897; GO:0003868; GO:0006572; GO:0046872; GO:0090729
|
Inferred from homology
| 2 | null | null | null |
PF00903;PF14696;
|
IPR005956;IPR041735;IPR041736;IPR029068;IPR004360;IPR037523;
| null |
cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Gammaproteobacteria (class), Vibrionales (order), Vibrionaceae (family), Vibrio (genus), Vibrio vulnificus (species)
|
vllY VV1_2768
| true |
Vibrio vulnificus
| 1 |
row_5780
| false | null |
6,062 |
P09807
|
MKIYHIFSVCYLITLCAAAATTAREEFFLCYDLIRYLKQYEKTGESKLVEQTFFNSIKNLDINSREYMELVYNKIAGISNERNKFENIYKDGDSISQVVERAVSEKKLTFGLNGKGLYVPENGEPRLKGYASIIERITLDLMEIYSIKGLNDIPRDIKFNMEKIRQERYNQMKEALNSVEGYKGKIVASDSDWCFKDPQGNRITDFDSINKELGLGRRDVKLDKGHDDLIKLCTEKIDSMNNLQNGKCV
|
Killer toxin subunit gamma (RF3 protein)
|
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica)
| 284,590 | 249 | 28,742 |
Direct protein sequencing;Plasmid;Signal;Toxin
|
GO:0090729
|
Evidence at protein level
| 2 | null |
SIGNAL 1..20; /evidence="ECO:0000255"
| null | null | null | null |
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Fungi (kingdom), Dikarya (subkingdom), Ascomycota (phylum), saccharomyceta (clade), Saccharomycotina (subphylum), Saccharomycetes (class), Saccharomycetales (order), Saccharomycetaceae (family), Kluyveromyces (genus), Kluyveromyces lactis (species)
| null | true |
Kluyveromyces lactis
| 0 |
row_5821
| false | null |
6,080 |
P0A3R6
|
MLRRFPTRTTAPGQGGARRSRVRALAWLLASGAMTHLSPALADVPYVLVKTNMVVTSVAMKPYEVTPTRMLVCGIAAKLGAAASSPDAHVPFCFGKDLKRPGSSPMEVMLRAVFMQQRPLRMFLGPKQLTFEGKPALELIRMVECSGKQDCP
|
Pertussis toxin subunit 4 (PTX S4) (Islet-activating protein S4) (IAP S4)
|
Bordetella parapertussis (strain 12822 / ATCC BAA-587 / NCTC 13253)
| 257,311 | 152 | 16,544 |
Disulfide bond;Host cell membrane;Host membrane;Membrane;Secreted;Signal;Toxin;Virulence;Whooping cough
|
GO:0005576; GO:0016020; GO:0020002; GO:0090729
|
Inferred from homology
| 2 |
SUBCELLULAR LOCATION: Secreted. Host cell membrane {ECO:0000305}.
|
SIGNAL 1..42; /evidence="ECO:0000250"
| null |
PF09275;
|
IPR008992;IPR015355;
| null |
cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Betaproteobacteria (class), Burkholderiales (order), Alcaligenaceae (family), Bordetella (genus), Bordetella parapertussis (species)
|
ptxD BPP4306
| true |
Bordetella parapertussis
| 0 |
row_5838
| false | null |
6,174 |
P0C8C2
|
EQLIKKDVKHKDKFAKKSECVRAAAAAFTGGDKS
|
Scolopendra 5848.48 Da toxin
|
Scolopendra viridicornis nigra (Brazilian giant centipede)
| 486,497 | 34 | 3,706 |
Direct protein sequencing;Neurotoxin;Secreted;Toxin
|
GO:0005576; GO:0090729
|
Evidence at protein level
| 2 |
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:17320133}.
| null | null | null | null | null |
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Protostomia (clade), Ecdysozoa (clade), Panarthropoda (clade), Arthropoda (phylum), Mandibulata (clade), Myriapoda (subphylum), Chilopoda (class), Pleurostigmophora (subclass), Epimorpha (clade), Scolopendromorpha (order), Scolopendridae (family), Scolopendra (genus), Scolopendra viridicornis (species)
| null | true |
Scolopendra viridicornis
| 0 |
row_5932
| false | null |
6,173 |
P0C8B7
|
SETDSRKEGRMGQKNAVIRQWCENDCNYAPK
|
Scolopendra 4610.56 Da toxin [Cleaved into: Scolopendra 3464.34 Da toxin]
|
Scolopendra viridicornis nigra (Brazilian giant centipede)
| 486,497 | 31 | 3,615 |
Direct protein sequencing;Disulfide bond;Neurotoxin;Secreted;Toxin
|
GO:0005576; GO:0090729
|
Evidence at protein level
| 2 |
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:17320133}.
| null | null | null | null | null |
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Protostomia (clade), Ecdysozoa (clade), Panarthropoda (clade), Arthropoda (phylum), Mandibulata (clade), Myriapoda (subphylum), Chilopoda (class), Pleurostigmophora (subclass), Epimorpha (clade), Scolopendromorpha (order), Scolopendridae (family), Scolopendra (genus), Scolopendra viridicornis (species)
| null | true |
Scolopendra viridicornis
| 1 |
row_5931
| false | null |
6,180 |
P0C8D3
|
AVQLLEVNPEIAQNS
|
Scolopendra 10564.33 Da toxin
|
Scolopendra viridicornis nigra (Brazilian giant centipede)
| 486,497 | 15 | 1,625 |
Direct protein sequencing;Neurotoxin;Secreted;Toxin
|
GO:0005576; GO:0090729
|
Evidence at protein level
| 2 |
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:17320133}.
| null | null | null | null | null |
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Protostomia (clade), Ecdysozoa (clade), Panarthropoda (clade), Arthropoda (phylum), Mandibulata (clade), Myriapoda (subphylum), Chilopoda (class), Pleurostigmophora (subclass), Epimorpha (clade), Scolopendromorpha (order), Scolopendridae (family), Scolopendra (genus), Scolopendra viridicornis (species)
| null | true |
Scolopendra viridicornis
| 2 |
row_5936
| false | null |
6,176 |
P0C8C4
|
AKEKEVTFQSGGPT
|
Scolopendra 5885.28 Da toxin
|
Scolopendra viridicornis nigra (Brazilian giant centipede)
| 486,497 | 14 | 1,479 |
Direct protein sequencing;Neurotoxin;Secreted;Toxin
|
GO:0005576; GO:0090729
|
Evidence at protein level
| 2 |
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:17320133}.
| null | null | null | null | null |
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Protostomia (clade), Ecdysozoa (clade), Panarthropoda (clade), Arthropoda (phylum), Mandibulata (clade), Myriapoda (subphylum), Chilopoda (class), Pleurostigmophora (subclass), Epimorpha (clade), Scolopendromorpha (order), Scolopendridae (family), Scolopendra (genus), Scolopendra viridicornis (species)
| null | true |
Scolopendra viridicornis
| 3 |
row_5933
| false | null |
6,178 |
P0C8C8
|
FKSLTKYSPGRQN
|
Scolopendra 6940.74 Da toxin
|
Scolopendra viridicornis nigra (Brazilian giant centipede)
| 486,497 | 13 | 1,526 |
Direct protein sequencing;Neurotoxin;Secreted;Toxin
|
GO:0005576; GO:0090729
|
Evidence at protein level
| 2 |
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:17320133}.
| null | null | null | null | null |
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Protostomia (clade), Ecdysozoa (clade), Panarthropoda (clade), Arthropoda (phylum), Mandibulata (clade), Myriapoda (subphylum), Chilopoda (class), Pleurostigmophora (subclass), Epimorpha (clade), Scolopendromorpha (order), Scolopendridae (family), Scolopendra (genus), Scolopendra viridicornis (species)
| null | true |
Scolopendra viridicornis
| 4 |
row_5935
| false | null |
6,764 |
P55870
|
MKNKKPRKFITQAPTLSLLALALLAGSVQAEDIGERTDQGTAMLASLQSEQGLIYLNADVWLKRQGATPLMTRDQLRERVLARGERLFIDFSAVTDQSERQQTRKAMEQLAGISFDADWVLVSGYKGELLFTPLGGVDDPAFYQVMERVESLEGQGKRHKRSLTQPPAAEAGLPHVAFYLNVNRKISDAECTFPRSRTWSRGDRLFCDSPNISLVYRVNLERSLQFGNTGSATPDAKIVRISLDEESAGAGIQLNEDLTWSENIADYLLLDGWARDYATDAIAQDYRFSIEASNTKAAVLKSLPTNLNSKYEHREISGFEVGVTGGVEVNKDGPKAKLEASAKFSQQRQLAYNTQDYRVERSAPSAQKVSFSWVRDQYATAESLLSSKTATVWGMGYDVDHNRIQPLSYKGFVPNLDVIYKAAPDETGSTEFKIDSSVNIRPIYTGIYKHYYVVGAHVSFQGFEDTDKRRRVTASTSFKVDWNHPVFTGGRPVNLQLGGFDNRCLSADANHGLSAVTCDETSAAQSFIYDQYGRYVSAQDTRRCLDGNNLGQLQSCSLSLGQRWEWKADSDALSNLSAHQLLGHDKQSGALGLYDENGNPQNVSVRTLTSYTRIFGPPASH
|
Hemolysin ahh1
|
Aeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / DSM 30187 / BCRC 13018 / CCUG 14551 / JCM 1027 / KCTC 2358 / NCIMB 9240 / NCTC 8049)
| 380,703 | 621 | 68,907 |
Cytolysis;Hemolysis;Lectin;Reference proteome;Signal;Toxin;Virulence
|
GO:0005576; GO:0030246; GO:0051715; GO:0090729
|
Inferred from homology
| 2 | null |
SIGNAL 1..30; /evidence="ECO:0000255"
| null |
PF12563;PF07968;
|
IPR022220;IPR043080;IPR044883;IPR016183;IPR036435;IPR035992;IPR000772;
| null |
cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Gammaproteobacteria (class), Aeromonadales (order), Aeromonadaceae (family), Aeromonas (genus), Aeromonas hydrophila (species), Aeromonas hydrophila subsp. hydrophila (subspecies)
|
ahh1 AHA_1512
| true |
Aeromonas hydrophila
| 0 |
row_6511
| false | null |
7,123 |
Q4L5M1
|
MSKLVQAISDAVQAGQNQDWAKLGTSIVGIVENGVGILGKLFGF
|
Antibacterial protein 3 homolog
|
Staphylococcus haemolyticus (strain JCSC1435)
| 279,808 | 44 | 4,561 |
Antibiotic;Antimicrobial;Cytolysis;Hemolysis;Secreted;Toxin;Virulence
|
GO:0005576; GO:0031640; GO:0042742; GO:0090729
|
Inferred from homology
| 2 |
SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
| null | null |
PF05480;
|
IPR008846;
| null |
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Bacillota (phylum), Bacilli (class), Bacillales (order), Staphylococcaceae (family), Staphylococcus (genus), Staphylococcus haemolyticus (species)
|
SH1743; SH1745
| true |
Staphylococcus haemolyticus
| 0 |
row_6844
| false | null |
7,124 |
Q4L5M2
|
MEKIANAVKSAIEAGQNQDWTKLGTSILDIVSNGVTELSKIFGF
|
Antibacterial protein 2 homolog
|
Staphylococcus haemolyticus (strain JCSC1435)
| 279,808 | 44 | 4,725 |
Antibiotic;Antimicrobial;Cytolysis;Hemolysis;Secreted;Toxin;Virulence
|
GO:0005576; GO:0031640; GO:0042742; GO:0090729
|
Inferred from homology
| 2 |
SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
| null | null |
PF05480;
|
IPR008846;
| null |
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Bacillota (phylum), Bacilli (class), Bacillales (order), Staphylococcaceae (family), Staphylococcus (genus), Staphylococcus haemolyticus (species)
|
SH1742; SH1744
| true |
Staphylococcus haemolyticus
| 1 |
row_6845
| false | null |
7,125 |
Q4L5M5
|
MQKLAEAIAAAVQAGQDKDWGKMGTSIVGIVENGISVLGKIFGF
|
Antibacterial protein 1 homolog
|
Staphylococcus haemolyticus (strain JCSC1435)
| 279,808 | 44 | 4,550 |
Antibiotic;Antimicrobial;Cytolysis;Hemolysis;Secreted;Toxin;Virulence
|
GO:0005576; GO:0031640; GO:0042742; GO:0090729
|
Inferred from homology
| 2 |
SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
| null | null |
PF05480;
|
IPR008846;
| null |
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Bacillota (phylum), Bacilli (class), Bacillales (order), Staphylococcaceae (family), Staphylococcus (genus), Staphylococcus haemolyticus (species)
|
SH1741
| true |
Staphylococcus haemolyticus
| 2 |
row_6846
| false | null |
7,137 |
Q4UK99
|
MLKSSKKEDSSKKNQNNKLIFTVRKLFSPIKNFFRKTKTPDNFFGVIKRLKINSQKMTLDERNILANLLELEDKTIEDIMVPRSDIAAIKLTTNLEELSESIKLEVPHTRTLIYDGTLDNVVGFIHIKDLFKALATKQNGRLKKLIRKHIIAAPSMKLLDLLAKMRRERTHIAIVVDEYGGTDGLVTIEDLIEEIVGRIDDEHDQQLDSDNFKVINNSTIISNARVEVEVLEEIIGEKLKNDDDEFDTIGGLVLTRVGSVPAIGTRIDISENIEIEVTDATPRSLKQVKIRLKNGLNSK
|
Hemolysin C
|
Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi)
| 315,456 | 299 | 33,883 |
CBS domain;Cytolysis;Hemolysis;Repeat;Toxin;Virulence
|
GO:0005886; GO:0031640; GO:0050660; GO:0090729
|
Inferred from homology
| 2 | null | null | null |
PF00571;PF03471;
|
IPR000644;IPR046342;IPR036318;IPR016169;IPR044751;IPR005170;
| null |
cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), spotted fever group (no rank), Rickettsia felis (species)
|
tlyC RF_1185
| true |
Rickettsia felis
| 0 |
row_6858
| false | null |
7,221 |
Q68W10
|
MLKSSKKEDSSSKKNQDNKLIFIVRQLFYLIKHLFSKTKTPDNFFGIIKRLKINSKKMSLDECNILANLLQLENKTVEDIMVPRSDIVAIKLTTNLAELSESIKIEVPHTRTLIYDGTLDNVVGFIHIKDLFKALATKQNSTLKRLIRKHIIAAPSMKLLDLLAKMRRERTHIAIVVDEYGGTDGLVTIEDLIEEIVGRIDDEHDQQLDSTNFKVINNSTIIANARIEVELLEEIIKEKIKNDDDEFDTIGGLVLTRVSSVPAIGTRIDISENIEIEVIDATPRSLKQVKIRLKNGLNRDSFNLT
|
Hemolysin C
|
Rickettsia typhi (strain ATCC VR-144 / Wilmington)
| 257,363 | 305 | 34,629 |
CBS domain;Cytolysis;Hemolysis;Repeat;Toxin;Virulence
|
GO:0005886; GO:0031640; GO:0050660; GO:0090729
|
Evidence at protein level
| 2 | null | null | null |
PF00571;PF03471;
|
IPR000644;IPR046342;IPR036318;IPR016169;IPR044751;IPR005170;
| null |
cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)
|
tlyC RT0725
| true |
Rickettsia typhi
| 0 |
row_6942
| false | null |
7,540 |
Q9FRT8
|
AADCNGACSPFEMPPCRSTDCRCIPIALFGGFCINPTGLSSVAKMIDEHPNLCQSDDECLKKGSGNFCARYPNHYMDYGWCFDSDSEAL
|
Albumin-1 (A1) [Cleaved into: Albumin-1 chain b (A1b) (Leginsulin); Albumin-1 chain a (A1a)]
|
Vigna radiata var. radiata (Mung bean) (Phaseolus aureus)
| 3,916 | 89 | 9,711 |
Disulfide bond;Knottin;Reference proteome;Seed storage protein;Signal;Storage protein;Toxin
|
GO:0045735; GO:0090729
|
Inferred from homology
| 2 | null |
SIGNAL <1..1; /evidence="ECO:0000255"
| null |
PF08027;PF16720;
|
IPR012512;IPR032000;
| null |
cellular organisms (no rank), Eukaryota (domain), Viridiplantae (kingdom), Streptophyta (phylum), Streptophytina (subphylum), Embryophyta (clade), Tracheophyta (clade), Euphyllophyta (clade), Spermatophyta (clade), Magnoliopsida (class), Mesangiospermae (clade), eudicotyledons (clade), Gunneridae (clade), Pentapetalae (clade), rosids (clade), fabids (clade), Fabales (order), Fabaceae (family), Papilionoideae (subfamily), 50 kb inversion clade (clade), NPAAA clade (clade), indigoferoid/millettioid clade (clade), Phaseoleae (tribe), Vigna (genus), Vigna radiata (species)
|
LEG
| true |
Vigna radiata
| 0 |
row_7259
| false | null |
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