Datasets:
manufernandezbur
/
tox_nontox_clustered_2025

Dataset card Data Studio Files
xet
Community
1
Unnamed: 0
int64
2
562k
Entry
stringlengths
6
10
Sequence
stringlengths
11
999
Protein names
stringlengths
5
558
Organism
stringclasses
392 values
Organism (ID)
int64
595
2.89M
Length
int64
11
999
Mass
int64
1.06k
118k
Keywords
stringlengths
4
380
⌀
Gene Ontology IDs
stringlengths
10
754
⌀
Protein existence
stringclasses
5 values
Annotation
float64
1
5
Subcellular location [CC]
stringlengths
30
2.26k
⌀
Signal peptide
stringclasses
677 values
Transmembrane
stringlengths
32
2.52k
⌀
Pfam
stringlengths
8
72
⌀
InterPro
stringlengths
10
180
⌀
PDB
stringlengths
5
2.65k
⌀
Taxonomic lineage
stringclasses
178 values
Gene Names
stringlengths
2
299
⌀
Toxin
bool
2 classes
species
stringclasses
111 values
cdhit_cluster
int64
0
4.65k
cdhit_rep
stringlengths
5
10
cdhit_rep_is_ref
bool
1 class
cdhit_pct_id
float64
26,834
P9WIK5
MLRVGPLTIGTLDDWAPSTGSTVSWRPSAVAHTKASQAPISDVPVSYMQAQHIRGYCEQKAKGLDYSRLMVVSCQQPGQCDIRAANYVINAHLRRHDTYRSWFQYNGNGQIIRRTIQDPADIEFVPVHHGELTLPQIREIVQNTPDPLQWGCFRFGIVQGCDHFTFFASVDHVHVDAMIVGVTLMEFHLMYAALVGGHAPLELPPAGSYDDFCRRQHTFSSTLTVESPQVRAWTKFAEGTNGSFPDFPLPLGDPSKPSDADIVTVMMLDEEQTAQFESVCTAAGARFIGGVLACCGLAEHELTGTTTYYGLTPRDTRRTPADAMTQGWFTGLIPITVPIAGSAFGDAARAAQTSFDSGVKLAEVPYDRVVELSSTLTMPRPNFPVVNFLDAGAAPLSVLLTAELTGTNIGVYSDGRYSYQLSIYVIRVEQGTAVAVMFPDNPIARESVARYLATLKSVFQRVAESGQQQNVA
Acyltransferase PapA3 (EC 2.3.1.278) (EC 2.3.1.279) (Long-chain-acyl-CoA--trehalose acyltransferase) (Mycolipenoyl-CoA--2-(long-chain-fatty acyl)-trehalose mycolipenoyltransferase) (Polyketide synthase-associated protein A3)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
472
51,575
Acyltransferase;Reference proteome;Transferase
GO:0005991; GO:0009247; GO:0016020; GO:0016409
Evidence at protein level
5
null
null
null
PF00668;
IPR023213;IPR001242;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
papA3 Rv1182
false
Mycobacterium tuberculosis
430
row_23479
false
null
81,801
P9WKB1
MRRLNGVDALMLYLDGGSAYNHTLKISVLDPSTDPDGWSWPKARQMFEERAHLLPVFRLRYLPTPLGLHHPIWVEDPEFDLDAHVRRVVCPAPGGMAEFCALVEQIYAHPLDRDRPLWQTWVVEGLDGGRVALVTLLHHAYSDGVGVLDMLAAFYNDTPDEAPVVAPPWEPPPLPSTRQRLGWALRDLPSRLGKIAPTVRAVRDRVRIEREFAKDGDRRVPPTFDRSAPPGPFQRGLSRSRRFSCESFPLAEVREVSKTLGVTINDVFLACVAGAVRRYLERCGSPPTDAMVATMPLAVTPAAERAHPGNYSSVDYVWLRADIADPLERLHATHLAAEATKQHFAQTKDADVGAVVELLPERLISGLARANARTKGRFDTFKNVVVSNVPGPREPRYLGRWRVDQWFSTGQISHGATLNMTVWSYCDQFNLCVMADAVAVRNTWELLGGFRASHEELLAAARAQATPKEMAT
Putative diacyglycerol O-acyltransferase Rv3087 (EC 2.3.1.20) (Putative triacylglycerol synthase Rv3087)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
472
52,597
Acyltransferase;Glycerol metabolism;Lipid biosynthesis;Lipid metabolism;Reference proteome;Transferase
GO:0001666; GO:0004144; GO:0005886; GO:0006071; GO:0008374; GO:0010447; GO:0019432; GO:0051701; GO:0052167; GO:0071731
Evidence at protein level
4
null
null
null
PF06974;PF03007;
IPR014292;IPR023213;IPR045034;IPR009721;IPR004255;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
Rv3087 MTV013.08
false
Mycobacterium tuberculosis
431
row_72247
false
null
81,808
P9WKE5
MTRRGKIVCTLGPATQRDDLVRALVEAGMDVARMNFSHGDYDDHKVAYERVRVASDATGRAVGVLADLQGPKIRLGRFASGATHWAEGETVRITVGACEGSHDRVSTTYKRLAQDAVAGDRVLVDDGKVALVVDAVEGDDVVCTVVEGGPVSDNKGISLPGMNVTAPALSEKDIEDLTFALNLGVDMVALSFVRSPADVELVHEVMDRIGRRVPVIAKLEKPEAIDNLEAIVLAFDAVMVARGDLGVELPLEEVPLVQKRAIQMARENAKPVIVATQMLDSMIENSRPTRAEASDVANAVLDGADALMLSGETSVGKYPLAAVRTMSRIICAVEENSTAAPPLTHIPRTKRGVISYAARDIGERLDAKALVAFTQSGDTVRRLARLHTPLPLLAFTAWPEVRSQLAMTWGTETFIVPKMQSTDGMIRQVDKSLLELARYKRGDLVVIVAGAPPGTVGSTNLIHVHRIGEDDV
Pyruvate kinase (PK) (EC 2.7.1.40)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
472
50,699
3D-structure;ATP-binding;Glycolysis;Kinase;Magnesium;Metal-binding;Nucleotide-binding;Phosphoprotein;Potassium;Pyruvate;Reference proteome;Transferase
GO:0000287; GO:0004743; GO:0005524; GO:0005737; GO:0005829; GO:0005886; GO:0006096; GO:0016301; GO:0030955
Evidence at protein level
4
null
null
null
PF00224;PF02887;
IPR001697;IPR015813;IPR040442;IPR011037;IPR018209;IPR015793;IPR015795;IPR036918;IPR015806;
5WRP;5WS8;5WS9;5WSA;5WSB;5WSC;6ITO;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
pyk pykA Rv1617 MTCY01B2.09
false
Mycobacterium tuberculosis
432
row_72254
false
null
213,004
P9WNQ3
MSGTVMQIVRVAILADSRLTEMALPAELPLREILPAVQRLVVPSAQNGDGGQADSGAAVQLSLAPVGGQPFSLDASLDTVGVVDGDLLVLQPVPAGPAAPGIVEDIADAAMIFSTSRLKPWGIAHIQRGALAAVIAVALLATGLTVTYRVATGVLAGLLAVAGIAVASALAGLLITIRSPRSGIALSIAALVPIGAALALAVPGKFGPAQVLLGAAGVAAWSLIALMIPSAERERVVAFFTAAAVVGASVALAAGAQLLWQLPLLSIGCGLIVAALLVTIQAAQLSALWARFPLPVIPAPGDPTPSAPPLRLLEDLPRRVRVSDAHQSGFIAAAVLLSVLGSVAIAVRPEALSVVGWYLVAATAAAATLRARVWDSAACKAWLLAQPYLVAGVLLVFYTATGRYVAAFGAVLVLAVLMLAWVVVALNPGIASPESYSLPLRRLLGLVAAGLDVSLIPVMAYLVGLFAWVLNR
ESX-3 secretion system protein EccD3 (ESX conserved component D3) (Type VII secretion system protein EccD3) (T7SS protein EccD3)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
472
47,944
Cell inner membrane;Cell membrane;Membrane;Reference proteome;Transmembrane;Transmembrane helix;Transport
GO:0005886; GO:0009274
Evidence at protein level
3
SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250|UniProtKB:B2HSU6}; Multi-pass membrane protein {ECO:0000255}.
null
TRANSMEM 121..141; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 155..175; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 183..203; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 211..231; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 236..256; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 258..278; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 327..347; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 349..369; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 381..401; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 405..425; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 450..470; /note="Helical"; /evidence="ECO:0000255"
PF08817;
IPR006707;IPR024962;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
eccD3 Rv0290
false
Mycobacterium tuberculosis
433
row_199205
false
null
425,422
P63716
MSGTSSMGLPPGPRLSGSVQAVLMLRHGLRFLTACQRRYGSVFTLHVAGFGHMVYLSDPAAIKTVFAGNPSVFHAGEANSMLAGLLGDSSLLLIDDDVHRDRRRLMSPPFHRDAVARQAGPIAEIAAANIAGWPMAKAFAVAPKMSEITLEVILRTVIGASDPVRLAALRKVMPRLLNVGPWATLALANPSLLNNRLWSRLRRRIEEADALLYAEIADRRADPDLAARTDTLAMLVRAADEDGRTMTERELRDQLITLLVAGHDTTATGLSWALERLTRHPVTLAKAVQAADASAAGDPAGDEYLDAVAKETLRIRPVVYDVGRVLTEAVEVAGYRLPAGVMVVPAIGLVHASAQLYPDPERFDPDRMVGATLSPTTWLPFGGGNRRCLGATFAMVEMRVVLREILRRVELSTTTTSGERPKLKHVIMVPHRGARIRVRATRDVSATSQATAQGAGCPAARGGGPSRAVGSQ
Putative cytochrome P450 135B1 (EC 1.14.-.-)
Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
233,413
472
50,688
Heme;Iron;Metal-binding;Monooxygenase;Oxidoreductase;Reference proteome
GO:0004497; GO:0005506; GO:0016705; GO:0020037
Inferred from homology
2
null
null
null
PF00067;
IPR001128;IPR017972;IPR002401;IPR036396;IPR050121;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype)
cyp135B1 BQ2027_MB0583
false
Mycobacterium tuberculosis
434
row_407523
false
null
212,752
P9WJX3
MTETASETGSWRELLSRYLGTSIVLAGGVALYATNEFLTISLLPSTIADIGGSRLYAWVTTLYLVGSVVAATTVNTMLLRVGARSSYLMGLAVFGLASLVCAAAPSMQILVAGRTLQGIAGGLLAGLGYALINSTLPKSLWTRGSALVSAMWGVATLIGPATGGLFAQLGLWRWAFGVMTLLTALMAMLVPVALGAGGVGPGGETPVGSTHKVPVWSLLLMGAAALAISVAALPNYLVQTAGLLAAAALLVAVFVVVDWRIHAAVLPPSVFGSGPLKWIYLTMSVQMIAAMVDTYVPLFGQRLGHLTPVAAGFLGAALAVGWTVGEVASASLNSARVIGHVVAAAPLVMASGLALGAVTQRADAPVGIIALWALALLIIGTGIGIAWPHLTVRAMDSVADPAESSAAAAAINVVQLISGAFGAGLAGVVVNTAKGGEVAAARGLYMAFTVLAAAGVIASYQATHRDRRLPR
Probable multidrug-efflux transporter Rv1634
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
471
47,713
Antibiotic resistance;Cell membrane;Membrane;Reference proteome;Transmembrane;Transmembrane helix;Transport
GO:0005886; GO:0015562; GO:0022857; GO:0046677; GO:0055085; GO:1990961
Evidence at protein level
3
SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
null
TRANSMEM 23..43; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 55..75; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 91..111; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 116..136; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 146..166; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 174..194; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 213..233; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 237..257; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 279..299; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 308..328; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 337..357; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 366..386; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 410..430; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 438..458; /note="Helical"; /evidence="ECO:0000255"
PF07690;
IPR011701;IPR020846;IPR036259;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
Rv1634
false
Mycobacterium tuberculosis
435
row_198956
false
null
431,508
P9WIF4
MSFVVTIPEALAAVATDLAGIGSTIGTANAAAAVPTTTVLAAAADEVSAAMAALFSGHAQAYQALSAQAALFHEQFVRALTAGAGSYAAAEAASAAPLEGVLDVINAPALALLGRPLIGNGANGAPGTGANGGDGGILIGNGGAGGSGAAGMPGGNGGAAGLFGNGGAGGAGGNVASGTAGFGGAGGAGGNGGLLFGAGGAGGVGGLAADAGDGGAGGDGGLFFGVGGAGGAGGTGTNVTGGAGGAGGNGGLLFGAGGVGGVGGDGVAFLGTAPGGPGGAGGAGGLFGVGGAGGAGGIGLVGNGGAGGSGGSALLWGDGGAGGAGGVGSTTGGAGGAGGNAGLLVGAGGAGGAGALGGGATGVGGAGGNGGTAGLLFGAGGAGGAGGFGFGGAGGAGGLGGKAGLIGDGGDGGAGGNGTGAKGGDGGAGGGAILVGNGGNGGNAGSGTPNGSAGTGGAGGLLGKNGMNGLP
PE-PGRS family protein PE_PGRS33
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
83,331
471
38,729
Cell outer membrane;Cell wall;Membrane;Reference proteome;Secreted;Virulence
GO:0005576; GO:0009279; GO:0009986
Inferred from homology
2
SUBCELLULAR LOCATION: Secreted, cell wall {ECO:0000250|UniProtKB:P9WIF5}. Cell surface {ECO:0000250|UniProtKB:P9WIF5}. Cell outer membrane {ECO:0000250|UniProtKB:P9WIF5}. Note=Exported to the cell surface via the ESX-5 / type VII secretion system (T7SS). {ECO:0000250|UniProtKB:P9WIF5}.
null
null
PF00934;PF21526;
IPR000084;IPR048996;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
PE_PGRS33 MT1866
false
Mycobacterium tuberculosis
436
row_413267
false
null
26,355
P95200
MTLSSGEPSAVGGRHRVVIIGSGFGGLNAAKALKRADVDITLISKTTTHLFQPLLYQVATGILSEGDIAPTTRLILRRQKNVRVLLGEVNAIDLKAQTVTSKLMDMTTVTPYDSLIVAAGAQQSYFGNDEFATFAPGMKTIDDALELRGRILGAFEAAEVSTDHAERERRLTFVVVGAGPTGVEVAGQIVELAERTLAGAFRTITPSECRVILLDAAPAVLPPMGPKLGLKAQRRLEKMDVEVQLNAMVTAVDYKGITIKEKDGGERRIECACKVWAAGVAASPLGKMIAEGSDGTEIDRAGRVIVEPDLTVKGHPNVFVVGDLMFVPGVPGVAQGAIQGARYATTVIKHMVKGNDDPANRKPFHYFNKGSMATISRHSAVAQVGKLEFAGYFAWLAWLVLHLVYLVGYRNRIAALFAWGISFMGRARGQMAITSQMIYARLVMTLMEQQAQGALAAAEQAEHAEQEAAG
Type II NADH:quinone oxidoreductase NdhA (EC 1.6.5.9) (Type II NADH dehydrogenase NdhA)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
470
50,385
Cell inner membrane;Cell membrane;FAD;Flavoprotein;Membrane;NAD;Oxidoreductase;Reference proteome;Transmembrane;Transmembrane helix
GO:0003955; GO:0005829; GO:0005886; GO:0016491; GO:0050136; GO:0051701
Evidence at protein level
5
SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000269|PubMed:15767566}; Single-pass membrane protein {ECO:0000255}.
null
TRANSMEM 389..409; /note="Helical"; /evidence="ECO:0000255"
PF07992;
IPR036188;IPR023753;IPR045024;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
ndhA Rv0392c
false
Mycobacterium tuberculosis
437
row_23070
false
null
321,090
A1KJ76
MSTNEGSLWGGRFAGGPSDALAALSKSTHFDWVLAPYDLTASRAHTMVLFRAGLLTEEQRDGLLAGLDSLAQDVADGSFGPLVTDEDVHAALERGLIDRVGPDLGGRLRAGRSRNDQVAALFRMWLRDAVRRVATGVLDVVGALAEQAAAHPSAIMPGKTHLQSAQPILLAHHLLAHAHPLLRDLDRIVDFDKRAAVSPYGSGALAGSSLGLDPDAIAADLGFSAAADNSVDATAARDFAAEAAFVFAMIAVDLSRLAEDIIVWSSTEFGYVTLHDSWSTGSSIMPQKKNPDIAELARGKSGRLIGNLAGLLATLKAQPLAYNRDLQEDKEPVFDSVAQLELLLPAMAGLVASLTFNVQRMAELAPAGYTLATDLAEWLVRQGVPFRSAHEAAGAAVRAAEQRGVGLQELTDDELAAISPELTPQVREVLTIEGSVSARDCRGGTAPGRVAEQLNAIGEAAERLRRQLVR
Argininosuccinate lyase (ASAL) (EC 4.3.2.1) (Arginosuccinase)
Mycobacterium bovis (strain BCG / Pasteur 1173P2)
410,289
470
49,774
Amino-acid biosynthesis;Arginine biosynthesis;Cytoplasm;Lyase
GO:0004056; GO:0005829; GO:0006526; GO:0042450
Inferred from homology
2
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00006}.
null
null
PF14698;PF00206;
IPR029419;IPR009049;IPR024083;IPR020557;IPR000362;IPR022761;IPR008948;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype), Mycobacterium tuberculosis variant bovis BCG (no rank)
argH BCG_1698
false
Mycobacterium tuberculosis
438
row_304462
false
null
431,950
P9WMX0
MTATRLPDGFAVQVDRRVRVLGDGSALLGGSPTRLLRLAPAARGLLCDGRLKVRDEVSAELARILLDATVAHPRPPSGPSHRDVTVVIPVRNNASGLRRLVTSLRGLRVIVVDDGSACPVESDDFVGAHCDIEVLHHPHSKGPAAARNTGLAACTTDFVAFLDSDVTPRRGWLESLLGHFCDPTVALVAPRIVSLVEGENPVARYEALHSSLDLGQREAPVLPHSTVSYVPSAAIVCRSSAIRDVGGFDETMHSGEDVDLCWRLIEAGARLRYEPIALVAHDHRTQLRDWIARKAFYGGSAAPLAVRHPDKTAPLVISGGALMAWILMSIGTGLGRLASLVIAVLTGRRIARAMRCAETSFLDVLAVATRGLWAAALQLASAICRHYWPLALLAAILSRRCRRVVLIAAVVDGVVDWLRRREGADDDAEPIGPLTYLVLKRVDDLAYGAGLWYGVVRERNIGALKPQIRT
Pre-mycofactocin glycosyltransferase (EC 2.4.1.-)
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
83,331
470
50,667
Cell membrane;Glycosyltransferase;Membrane;Reference proteome;Transferase;Transmembrane;Transmembrane helix
GO:0005886; GO:0016757
Inferred from homology
2
SUBCELLULAR LOCATION: Cell membrane {ECO:0000255}; Single-pass membrane protein {ECO:0000255}.
null
TRANSMEM 315..335; /note="Helical"; /evidence="ECO:0000255"
PF00535;
IPR001173;IPR023981;IPR029044;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
mftF MT0723
false
Mycobacterium tuberculosis
439
row_413705
false
null
432,049
P9WNR0
MPSPATTWLHVSGYRFLLRRIECALLFGDVCAATGALRARTTSLALGCVLAIVAAMGCAFVALLRPQSALGQAPIVMGRESGALYVRVDDVWHPVLNLASARLIAATNANPQPVSESELGHTKRGPLLGIPGAPQLLDQPLAGAESAWAICDSDNGGSTTVVVGPAEDSSAQVLTAEQMILVATESGSPTYLLYGGRRAVVDLADPAVVWALRLQGRVPHVVAQSLLNAVPEAPRITAPRIRGGGRASVGLPGFLVGGVVRITRASGDEYYVVLEDGVQRIGQVAADLLRFGDSQGSVNVPTVAPDVIRVAPIVNTLPVSAFPDRPPTPVDGSPGRAVTTLCVTWTPAQPGAARVAFLAGSGPPVPLGGVPVTLAQADGRGPALDAVYLPPGRSAYVAARSLSGGGTGTRYLVTDTGVRFAIHDDDVAHDLGLPTAAIPAPWPVLATLPSGPELSRANASVARDTVAPGP
ESX-4 secretion system ATPase EccB4 (EC 3.6.-.-) (ESX conserved component B4) (Type VII secretion system protein EccB4) (T7SS protein EccB4)
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
83,331
470
48,199
ATP-binding;Cell membrane;Hydrolase;Membrane;Nucleotide-binding;Reference proteome;Transmembrane;Transmembrane helix
GO:0005524; GO:0005576; GO:0005886; GO:0016787
Inferred from homology
2
SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
null
TRANSMEM 44..64; /note="Helical"; /evidence="ECO:0000255"
PF05108;
IPR007795;IPR044857;IPR042485;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
eccB4 MT3556
false
Mycobacterium tuberculosis
440
row_413796
false
null
26,962
P9WN99
MTTRLQAPVAVTPPLPTRRNAELLLLCFAAVITFAALLVVQANQDQGVPWDLTSYGLAFLTLFGSAHLAIRRFAPYTDPLLLPVVALLNGLGLVMIHRLDLVDNEIGEHRHPSANQQMLWTLVGVAAFALVVTFLKDHRQLARYGYICGLAGLVFLAVPALLPAALSEQNGAKIWIRLPGFSIQPAEFSKILLLIFFSAVLVAKRGLFTSAGKHLLGMTLPRPRDLAPLLAAWVISVGVMVFEKDLGASLLLYTSFLVVVYLATQRFSWVVIGLTLFAAGTLVAYFIFEHVRLRVQTWLDPFADPDGTGYQIVQSLFSFATGGIFGTGLGNGQPDTVPAASTDFIIAAFGEELGLVGLTAILMLYTIVIIRGLRTAIATRDSFGKLLAAGLSSTLAIQLFIVVGGVTRLIPLTGLTTPWMSYGGSSLLANYILLAILARISHGARRPLRTRPRNKSPITAAGTEVIERV
Peptidoglycan glycosyltransferase RodA (EC 2.4.99.28) (Non-canonical transglycosylase RodA)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
469
50,611
Cell inner membrane;Cell membrane;Cell shape;Cell wall biogenesis/degradation;Glycosyltransferase;Membrane;Peptidoglycan synthesis;Phosphoprotein;Reference proteome;Transferase;Transmembrane;Transmembrane helix
GO:0005886; GO:0008360; GO:0009252; GO:0015648; GO:0016757; GO:0032153; GO:0051301; GO:0052167; GO:0071555
Evidence at protein level
5
SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000255}.
null
TRANSMEM 20..40; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 50..70; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 76..96; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 115..135; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 146..166; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 183..203; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 226..246; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 248..264; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 267..287; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 312..332; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 344..364; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 386..406; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 418..438; /note="Helical"; /evidence="ECO:0000255"
PF01098;
IPR018365;IPR001182;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
rodA Rv0017c MTCY10H4.17c
false
Mycobacterium tuberculosis
441
row_23602
false
null
81,803
P9WKB7
MKRLSGWDAVLLYSETPNVHMHTLKVAVIELDSDRQEFGVDAFREVIAGRLHKLEPLGYQLVDVPLKFHHPMWREHCQVDLNYHIRPWRLRAPGGRRELDEAVGEIASTPLNRDHPLWEMYFVEGLANHRIAVVAKIHHALADGVASANMMARGMDLLPGPEVGRYVPDPAPTKRQLLSAAFIDHLRHLGRIPATIRYTTQGLGRVRRSSRKLSPALTMPFTPPPTFMNHRLTPERRFATATLALIDVKATAKLLGATINDMVLAMSTGALRTLLLRYDGKAEPLLASVPVSYDFSPERISGNRFTGMLVALPADSDDPLQRVRVCHENAVSAKESHQLLGPELISRWAAYWPPAGAEALFRWLSERDGQNKVLNLNISNVPGPRERGRVGAALVTEIYSVGPLTAGSGLNITVWSYVDQLNISVLTDGSTVQDPHEVTAGMIADFIEIRRAAGLSVELTVVESAMAQA
Putative diacyglycerol O-acyltransferase Rv0221 (EC 2.3.1.20) (Putative triacylglycerol synthase Rv0221)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
469
51,862
Acyltransferase;Glycerol metabolism;Lipid biosynthesis;Lipid metabolism;Reference proteome;Transferase
GO:0001666; GO:0004144; GO:0005886; GO:0006071; GO:0008374; GO:0019432; GO:0051701; GO:0071731
Evidence at protein level
4
null
null
null
PF06974;PF03007;
IPR014292;IPR045034;IPR009721;IPR004255;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
Rv0221 MTCY08D5.16
false
Mycobacterium tuberculosis
442
row_72249
false
null
126,214
A5U8Q5
MTDRARLRLHDTAAGVVRDFVPLRPGHVSIYLCGATVQGLPHIGHVRSGVAFDILRRWLLARGYDVAFIRNVTDIEDKILAKAAAAGRPWWEWAATHERAFTAAYDALDVLPPSAEPRATGHITQMIEMIERLIQAGHAYTGGGDVYFDVLSYPEYGQLSGHKIDDVHQGEGVAAGKRDQRDFTLWKGEKPGEPSWPTPWGRGRPGWHLECSAMARSYLGPEFDIHCGGMDLVFPHHENEIAQSRAAGDGFARYWLHNGWVTMGGEKMSKSLGNVLSMPAMLQRVRPAELRYYLGSAHYRSMLEFSETAMQDAVKAYVGLEDFLHRVRTRVGAVCPGDPTPRFAEALDDDLSVPIALAEIHHVRAEGNRALDAGDHDGALRSASAIRAMMGILGCDPLDQRWESRDETSAALAAVDVLVQAELQNREKAREQRNWALADEIRGRLKRAGIEVTDTADGPQWSLLGGDTK
Cysteine--tRNA ligase (EC 6.1.1.16) (Cysteinyl-tRNA synthetase) (CysRS)
Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra)
419,947
469
51,855
Aminoacyl-tRNA synthetase;ATP-binding;Cytoplasm;Ligase;Metal-binding;Nucleotide-binding;Protein biosynthesis;Reference proteome;Zinc
GO:0004817; GO:0005524; GO:0005829; GO:0006423; GO:0008270
Inferred from homology
3
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00041}.
null
null
PF09190;PF01406;
IPR015803;IPR015273;IPR024909;IPR014729;IPR032678;IPR009080;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
cysS MRA_3619
false
Mycobacterium tuberculosis
443
row_114396
false
null
26,768
P9WGU9
MVMSRGRIPRLGAAVLVALTTAAAACGADSQGLVVSFYTPATDGATFTAIAQRCNQQFGGRFTIAQVSLPRSPNEQRLQLARRLTGNDRTLDVMALDVVWTAEFAEAGWALPLSDDPAGLAENDAVADTLPGPLATAGWNHKLYAAPVTTNTQLLWYRPDLVNSPPTDWNAMIAEAARLHAAGEPSWIAVQANQGEGLVVWFNTLLVSAGGSVLSEDGRHVTLTDTPAHRAATVSALQILKSVATTPGADPSITRTEEGSARLAFEQGKAALEVNWPFVFASMLENAVKGGVPFLPLNRIPQLAGSINDIGTFTPSDEQFRIAYDASQQVFGFAPYPAVAPGQPAKVTIGGLNLAVAKTTRHRAEAFEAVRCLRDQHNQRYVSLEGGLPAVRASLYSDPQFQAKYPMHAIIRQQLTDAAVRPATPVYQALSIRLAAVLSPITEIDPESTADELAAQAQKAIDGMGLLP
Trehalose-binding lipoprotein LpqY (SugABC transporter substrate-binding protein LpqY) (SugABC transporter SBP LpqY)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
468
49,793
3D-structure;Cell inner membrane;Cell membrane;Disulfide bond;Lipoprotein;Membrane;Palmitate;Reference proteome;Signal;Sugar transport;Transport
GO:0005886; GO:0015574; GO:0015771; GO:0042597; GO:0043190; GO:0051701
Evidence at protein level
5
SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Lipid-anchor {ECO:0000255|PROSITE-ProRule:PRU00303}; Periplasmic side {ECO:0000269|PubMed:35775983}.
SIGNAL 1..25; /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
null
PF01547;
IPR006059;
7WCJ;7WDA;8JA7;8JA8;8JA9;8JAA;8JAB;8JAC;8JAD;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
lpqY Rv1235
false
Mycobacterium tuberculosis
444
row_23415
false
null
81,750
P9WIK7
MFSITTLRDWTPDPGSIICWHASPTAKAKARQAPISEVPPSYQQAQHLRRYRDHVARGLDMSRLMIFTWDLPGRCNIRAMNYAINAHLRRHDTYHSWFEFDNAEHIVRHTIADPADIEVVQAEHQNMTSAELRHHIATPQPLQWDCFLFGIIQSDDHFTFYASIAHLCVDPMIVGVLFIEIHMMYSALVGGDPPIELPPAGRYDDHCVRQYADTAALTLDSARVRRWVEFAANNDGTLPHFPLPLGDLSVPHTGKLLTETLMDEQQGERFEAACVAAGARFSGGVFACAALAERELTNCETFDVVTTTDTRRTPTELRTTGWFTGLVPITVPVASGLFDSAARVAQISFDSGKDLATVPFDRVLELARPETGLRPPRPGNFVMSFLDASIAPLSTVANSDLNFRIYDEGRVSHQVSMWVNRYQHQTTVTVLFPDNPIASESVANYIAAMKSIYIRTADGTLATLKPGT
Trehalose-2-sulfate acyltransferase PapA2 (EC 2.3.1.288) (2-O-sulfo trehalose long-chain-acyltransferase) (Polyketide synthase-associated protein A2)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
468
52,150
3D-structure;Acyltransferase;Cell wall biogenesis/degradation;Lipid biosynthesis;Lipid metabolism;Reference proteome;Transferase
GO:0016747; GO:0046506; GO:0071555
Evidence at protein level
4
null
null
null
PF00668;
IPR023213;IPR001242;
6AEF;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
papA2 Rv3820c
false
Mycobacterium tuberculosis
445
row_72197
false
null
81,883
P9WNT3
MESRWVLHLDMDAFFASVEQLTRPTLRGRPVLVGGLGGRGVVAGASYEARAYGARSAMPMHQARRLIGVTAVVLPPRGVVYGIASRRVFDTVRGLVPVVEQLSFDEAFAEPPQLAGAVAEDVETFCERLRRRVRDETGLIASVGAGSGKQIAKIASGLAKPDGIRVVRHAEEQALLSGLPVRRLWGIGPVAEEKLHRLGIETIGQLAALSDAEAANILGATIGPALHRLARGIDDRPVVERAEAKQISAESTFAVDLTTMEQLHEAIDSIAEHAHQRLLRDGRGARTITVKLKKSDMSTLTRSATMPYPTTDAGALFTVARRLLPDPLQIGPIRLLGVGFSGLSDIRQESLFADSDLTQETAAAHYVETPGAVVPAAHDATMWRVGDDVAHPELGHGWVQGAGHGVVTVRFETRGSGPGSARTFPVDTGDISNASPLDSLDWPDYIGQLSVEGSAGASAPTVDDVGDR
DNA polymerase IV 1 (Pol IV 1) (EC 2.7.7.7)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
468
49,765
3D-structure;Cytoplasm;DNA damage;DNA repair;DNA replication;DNA-binding;DNA-directed DNA polymerase;Magnesium;Metal-binding;Mutator protein;Nucleotidyltransferase;Reference proteome;Transferase
GO:0000287; GO:0003684; GO:0003887; GO:0005829; GO:0005886; GO:0006261; GO:0009432; GO:0042276
Evidence at protein level
4
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
null
null
PF00817;PF11799;PF11798;
IPR043502;IPR036775;IPR017961;IPR050116;IPR022880;IPR024728;IPR043128;IPR001126;
8DK9;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
dinB1 dinX Rv1537 MTCY48.28c
false
Mycobacterium tuberculosis
446
row_72324
false
null
112,133
A1KFY5
MSVLLFGVSHRSAPVVVLEQLSIDESDQVKIIDRVLASPLVTEAMVLSTCNRVEVYAVVDAFHGGLSVIGQVLAEHSGMSMGELTKYAYVRYSEAAVEHLFAVASGLDSAVIGEQQVLGQVRRAYAVAESNRTVGRVLHELAQRALSVGKRVHSETAIDAAGASVVSVALGMAERKLGSLAGTTAVVIGAGAMGALSAVHLTRAGVGHIQVLNRSLSRAQRLARRIRESGVPAEALALDRLANVLADADVVVSCTGAVRPVVSLADVHHALAAARRDEATRPLVICDLGMPRDVDPAVARLPCVWVVDVDSVQHEPSAHAAAADVEAARHIVAAEVASYLVGQRMAEVTPTVTALRQRAAEVVEAELLRLDNRLPGLQSVQREEVARTVRRVVDKLLHAPTVRIKQLASAPGGDSYAEALRELFELDQTAVDAVATAGELPVVPSGFDAESRRGGGDMQSSPKRSPSN
Glutamyl-tRNA reductase (GluTR) (EC 1.2.1.70)
Mycobacterium bovis (strain BCG / Pasteur 1173P2)
410,289
468
49,361
NADP;Oxidoreductase;Porphyrin biosynthesis
GO:0008883; GO:0019353; GO:0050661
Inferred from homology
3
null
null
null
PF00745;PF05201;PF01488;
IPR000343;IPR015896;IPR015895;IPR018214;IPR036453;IPR036343;IPR036291;IPR006151;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype), Mycobacterium tuberculosis variant bovis BCG (no rank)
hemA BCG_0552
false
Mycobacterium tuberculosis
447
row_100600
false
null
112,181
A1KJ30
MRMLPSYIPSPPRGVWYLGPLPVRAYAVCVITGIIVALLIGDRRLTARGGERGMTYDIALWAVPFGLIGGRLYHLATDWRTYFGDGGAGLAAALRIWDGGLGIWGAVTLGVMGAWIGCRRCGIPLPVLLDAVAPGVVLAQAIGRLGNYFNQELYGRETTMPWGLEIFYRRDPSGFDVPNSLDGVSTGQVAFVVQPTFLYELIWNVLVFVALIYIDRRFIIGHGRLFGFYVAFYCAGRFCVELLRDDPATLIAGIRINSFTSTFVFIGAVVYIILAPKGREAPGALRGSEYVVDEALEREPAELAAAAVASAASAVGPVGPGEPNQPDDVAEAVKAEVAEVTDEVAAESVVQVADRDGESTPAVEETSEADIEREQPGDLAGQAPAAHQVDAEAASAAPEEPAALASEAHDETEPEVPEKAAPIPDPAKPDELAVAGPGDDPAEPDGIRRQDDFSSRRRRWWRLRRRRQ
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase (EC 2.5.1.145)
Mycobacterium bovis (strain BCG / Pasteur 1173P2)
410,289
468
50,392
Cell membrane;Membrane;Transferase;Transmembrane;Transmembrane helix
GO:0005886; GO:0008961; GO:0042158
Inferred from homology
3
SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01147}; Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01147}.
null
TRANSMEM 21..41; /note="Helical"; /evidence="ECO:0000255|HAMAP-Rule:MF_01147"; TRANSMEM 56..76; /note="Helical"; /evidence="ECO:0000255|HAMAP-Rule:MF_01147"; TRANSMEM 96..116; /note="Helical"; /evidence="ECO:0000255|HAMAP-Rule:MF_01147"; TRANSMEM 192..212; /note="Helical"; /evidence="ECO:0000255|HAMAP-Rule:MF_01147"; TRANSMEM 218..238; /note="Helical"; /evidence="ECO:0000255|HAMAP-Rule:MF_01147"; TRANSMEM 256..276; /note="Helical"; /evidence="ECO:0000255|HAMAP-Rule:MF_01147"
PF01790;
IPR001640;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype), Mycobacterium tuberculosis variant bovis BCG (no rank)
lgt BCG_1652
false
Mycobacterium tuberculosis
448
row_100646
false
null
112,237
A1KM51
MREYDIVVIGSGPGGQKAAIASAKLGKSVAIVERGRMLGGVCVNTGTIPSKTLREAVLYLTGMNQRELYGASYRVKDRITPADLLARTQHVIGKEVDVVRNQLMRNRVDLIVGHGRFIDPHTILVEDQARREKTTVTGDYIIIATGTRPARPSGVEFDEERVLDSDGILDLKSLPSSMVVVGAGVIGIEYASMFAALGTKVTVVEKRDNMLDFCDPEVVEALKFHLRDLAVTFRFGEEVTAVDVGSAGTVTTLASGKQIPAETVMYSAGRQGQTDHLDLHNAGLEVQGRGRIFVDDRFQTKVDHIYAVGDVIGFPALAATSMEQGRLAAYHAFGEPTDGITELQPIGIYSIPEVSYVGATEVELTKSSIPYEVGVARYRELARGQIAGDSYGMLKLLVSTEDLKLLGVHIFGTSATEMVHIGQAVMGCGGSVEYLVDAVFNYPTFSEAYKNAALDVMNKMRALNQFRR
Soluble pyridine nucleotide transhydrogenase (STH) (EC 1.6.1.1) (NAD(P)(+) transhydrogenase [B-specific])
Mycobacterium bovis (strain BCG / Pasteur 1173P2)
410,289
468
50,754
Cytoplasm;FAD;Flavoprotein;NAD;NADP;Oxidoreductase
GO:0003957; GO:0004148; GO:0005829; GO:0006103; GO:0006739; GO:0050660
Inferred from homology
3
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00247}.
null
null
PF07992;PF02852;
IPR050151;IPR036188;IPR023753;IPR016156;IPR001100;IPR004099;IPR022962;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype), Mycobacterium tuberculosis variant bovis BCG (no rank)
sthA BCG_2726
false
Mycobacterium tuberculosis
449
row_100702
false
null
431,454
P9WI03
MDFGLQPPEITSGEMYLGPGAGPMLAAAVAWDGLAAELQSMAASYASIVEGMASESWLGPSSAGMAAAAAPYVTWMSGTSAQAKAAADQARAAVVAYETAFAAVVPPPQIAANRSQLISLVATNIFGQNTAAIAATEAEYGEMWAQDTMAMFGYASSSATASRLTPFTAPPQTTNPSGLAGQAAATGQATALASGTNAVTTALSSAAAQFPFDIIPTLLQGLATLSTQYTQLMGQLINAIFGPTGATTYQNVFVTAANVTKFSTWANDAMSAPNLGMTEFKVFWQPPPAPEIPKSSLGAGLGLRSGLSAGLAHAASAGLGQANLVGDLSVPPSWASATPAVRLVANTLPATSLAAAPATQIPANLLGQMALGSMTGGALGAAAPAIYTGSGARARANGGTPSAEPVKLEAVIAQLQKQPDAVRHWNVDKADLDGLLDRLSKQPGIHAVHVSNGDKPKVALPDTQLGSH
Uncharacterized PPE family protein PPE33
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
468
47,156
Reference proteome
GO:0010961; GO:0052572; GO:1903830
Evidence at protein level
2
null
null
null
PF00823;PF12484;
IPR022171;IPR000030;IPR038332;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
PPE33 Rv1809
false
Mycobacterium tuberculosis
450
row_413213
false
null
495,378
Q79G04
MSYVIAAPEMLATTAADVDGIGSAIRAASASAAGPTTGLLAAAADEVSSAAAALFSEYARECQEVLKQAAAFHGEFTRALAAAGAAYAQAEASNTAAMSGTAGSSGALGSVGMLSGNPLTALMMGGTGEPILSDRVLAIIDSAYIRPIFGPNNPVAQYTPEQWWPFIGNLSLDQSIAQGVTLLNNGINAELQNGHDVVVFGYSQSAAVATNEIRALMALPPGQAPDPSRLAFTLIGNINNPNGGVLERYVGLYLPFLDMSFNGATPPDSPYQTYMYTGQYDGYAHNPQYPLNILSDLNAFMGIRWVHNAYPFTAAEVANAVPLPTSPGYTGNTHYYMFLTQDLPLLQPIRAIPFVGTPIAELIQPDLRVLVDLGYGYGYADVPTPASLFAPINPIAVASALATGTVQGPQAALVSIGLLPQSALPNTYPYLPSANPGLMFNFGQSSVTELSVLSGALGSVARLIPPIA
PE family protein PE3
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
468
48,608
Cell wall;Reference proteome;Secreted;Virulence
GO:0005576
Evidence at protein level
2
SUBCELLULAR LOCATION: Secreted, cell wall {ECO:0000269|PubMed:23708146}.
null
null
PF00934;PF08237;
IPR029058;IPR000084;IPR013228;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
PE3 Rv0159c
false
Mycobacterium tuberculosis
451
row_476165
false
null
432,043
P9WNQ0
MPTSDPGLRRVTVHAGAQAVDLTLPAAVPVATLIPSIVDILGDRGASPATAARYQLSALGAPALPNATTLAQCGIRDGAVLVLHKSSAQPPTPRCDDVAEAVAAALDTTARPQCQRTTRLSGALAASCITAGGGLMLVRNALGTNVTRYSDATAGVVAAAGLAALLFAVIACRTYRDPIAGLTLSVIATIFGAVAGLLAVPGVPGVHSVLVAAMAAAATSVLAMRITGCGGITLTAVACCAVVVAAATLVGAITAAPVPAIGSLATLASFGLLEVSARMAVLLAGLSPRLPPALNPDDADALPTTDRLTTRANRADAWLTSLLAAFAASATIGAIGTAVATHGIHRSSMGGIALAAVTGALLLLRARSADTRRSLVFAICGITTVATAFTVAADRALEHGPWIAALTAMLAAVAMFLGFVAPALSLSPVTYRTIELLECLALIAMVPLTAWLCGAYSAVRHLDLTWT
ESX-4 secretion system protein eccD4 (ESX conserved component D4) (Type VII secretion system protein eccD4) (T7SS protein eccD4)
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
83,331
467
46,731
Cell membrane;Membrane;Reference proteome;Transmembrane;Transmembrane helix
GO:0005886
Inferred from homology
2
SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
null
TRANSMEM 122..142; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 152..172; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 186..206; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 209..229; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 241..261; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 264..284; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 319..339; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 344..364; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 374..394; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 401..421; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 439..459; /note="Helical"; /evidence="ECO:0000255"
PF19053;PF08817;
IPR044049;IPR006707;IPR024962;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
eccD4 MT3554
false
Mycobacterium tuberculosis
452
row_413790
false
null
81,673
P9WG55
MKSTVEQLSPTRVRINVEVPFAELEPDFQRAYKELAKQVRLPGFRPGKAPAKLLEARIGREAMLDQIVNDALPSRYGQAVAESDVQPLGRPNIEVTKKEYGQDLQFTAEVDIRPKISPPDLSALTVSVDPIEIGEDDVDAELQSLRTRFGTLTAVDRPVAVGDVVSIDLSATVDGEDIPNAAAEGLSHEVGSGRLIAGLDDAVVGLSADESRVFTAKLAAGEHAGQEAQVTVTVRSVKERELPEPDDEFAQLASEFDSIDELRASLSDQVRQAKRAQQAEQIRNATIDALLEQVDVPLPESYVQAQFDSVLHSALSGLNHDEARFNELLVEQGSSRAAFDAEARTASEKDVKRQLLLDALADELQVQVGQDDLTERLVTTSRQYGIEPQQLFGYLQERNQLPTMFADVRRELAIRAAVEAATVTDSDGNTIDTSEFFGKRVSAGEAEEAEPADEGAARAASDEATT
Trigger factor (TF) (EC 5.2.1.8) (PPIase)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
466
50,616
Cell cycle;Cell division;Chaperone;Cytoplasm;Isomerase;Reference proteome;Rotamase;Stress response
GO:0003755; GO:0005829; GO:0005886; GO:0009267; GO:0009274; GO:0015031; GO:0043022; GO:0043335; GO:0044183; GO:0046677; GO:0051083; GO:0051301; GO:0061077
Evidence at protein level
4
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00303}. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm. {ECO:0000255|HAMAP-Rule:MF_00303}.
null
null
PF00254;PF05698;PF05697;
IPR046357;IPR001179;IPR005215;IPR008880;IPR037041;IPR008881;IPR036611;IPR027304;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
tig Rv2462c MTV008.18c
false
Mycobacterium tuberculosis
453
row_72122
false
null
190,592
P0A587
MVDGGGGASDLLVIFGITGDLARKMTFRALYRLERHQLLDCPILGVASDDMSVGQLVKWARESIGRTEKIDDAVFDRLAGRLSYLHGDVTDSQLYDSLAELIGSACRPLYYLEMPPALFAPIVENLANVRLLERARVAVEKPFGHDLASALELNARLRAVLGEDQILRVDHFLGKQPVVELEYLRFANQALAELWDRNSISEIHITMAEDFGVEDRGKFYDAVGALRDVVQNHLLQVLALVTMEPPVGSSADDLNDKKAEVFRAMAPLDPDRCVRGQYLGYTEVAGVASDSATETYVALRTEIDNWRWAGVPIFVRAGKELPAKVTEVRLFLRRVPALAFLPNRRPAEPNQIVLRIDPDPGMRLQISAHTDDSWRDIHLDSSFAVDLGEPIRPYERLLYAGLVGDHQLFAREDSIEQTWRIVQPLLDNPGEIHRYDRGSWGPEAAQSLLRGHRGWQSPWLPRGTDA
Glucose-6-phosphate 1-dehydrogenase 1 (G6PD 1) (EC 1.1.1.49)
Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
233,413
466
52,173
Carbohydrate metabolism;Glucose metabolism;NADP;Oxidoreductase;Reference proteome
GO:0004345; GO:0005829; GO:0006006; GO:0009051; GO:0050661
Inferred from homology
3
null
null
null
PF02781;PF00479;
IPR001282;IPR019796;IPR022675;IPR022674;IPR036291;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype)
zwf1 zwf BQ2027_MB1152
false
Mycobacterium tuberculosis
454
row_177437
false
null
405,643
O53379
MPRIRKPPSRSLPEPSAALANTTTRNLWLHFARHGAGIQHPVIVRGDGVTIFDDRGKSYLDALSGLFVVQVGYGRAELAEAAARQAGTLGYFPLWGYATPPAIELAERLARYAPGDLNRVFFTSGGTEAVETAWKVAKQYFKLTGKPGKQKVISRSIAYHGTTQGALAITGLPLFKAPFEPLTPGGFRVPNTNFYRAPLHTDLKEFGRWAADRIAEAIEFEGPDTVAAVFLEPVQNAGGCIPAPPGYFERVREICDRYDVLLVSDEVICAFGRIGSMFACEDLGYVPDMITCAKGLTSGYSPLGAMIASDRLFEPFNDGETMFAHGYTFGGHPVSAAVGLANLDIFEREGLSDHVKRNSPALRATLEKLYDLPIVGDIRGEGYFFGIELVKDQATKQTFTDDERARLLGQVSAALFEAGLYCRTDDRGDPVVQVAPPLISGQPEFDTIETILRSVLTDTGRKYLHL
Probable aminotransferase Rv3329 (EC 2.6.1.-)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
466
50,843
Aminotransferase;Direct protein sequencing;Pyridoxal phosphate;Reference proteome;Transferase
GO:0004015; GO:0009102; GO:0030170
Evidence at protein level
2
null
null
null
PF00202;
IPR005814;IPR049704;IPR015424;IPR015421;IPR015422;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
Rv3329 RVBD_3329 P425_03469
false
Mycobacterium tuberculosis
455
row_388162
false
null
6,637
O53896
MAKLARVVGLVQEEQPSDMTNHPRYSPPPQQPGTPGYAQGQQQTYSQQFDWRYPPSPPPQPTQYRQPYEALGGTRPGLIPGVIPTMTPPPGMVRQRPRAGMLAIGAVTIAVVSAGIGGAAASLVGFNRAPAGPSGGPVAASAAPSIPAANMPPGSVEQVAAKVVPSVVMLETDLGRQSEEGSGIILSAEGLILTNNHVIAAAAKPPLGSPPPKTTVTFSDGRTAPFTVVGADPTSDIAVVRVQGVSGLTPISLGSSSDLRVGQPVLAIGSPLGLEGTVTTGIVSALNRPVSTTGEAGNQNTVLDAIQTDAAINPGNSGGALVNMNAQLVGVNSAIATLGADSADAQSGSIGLGFAIPVDQAKRIADELISTGKASHASLGVQVTNDKDTLGAKIVEVVAGGAAANAGVPKGVVVTKVDDRPINSADALVAAVRSKAPGATVALTFQDPSGGSRTVQVTLGKAEQ
Serine protease PepD (EC 3.4.21.107) (HtrA-like serine protease)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
464
46,453
3D-structure;Cell inner membrane;Cell membrane;Cell wall;Hydrolase;Membrane;Protease;Reference proteome;Secreted;Serine protease;Stress response;Transmembrane;Transmembrane helix
GO:0004252; GO:0005576; GO:0005886; GO:0006508; GO:0008236; GO:0030163; GO:0071236
Evidence at protein level
5
SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000269|PubMed:21445360}; Single-pass membrane protein {ECO:0000255}. Secreted, cell wall {ECO:0000269|PubMed:21445360}. Secreted {ECO:0000269|PubMed:21445360}. Note=Traffics from the cytoplasm through the cell membrane to the cell wall where it is autoprocessed and eventually secreted into the culture filtrate protein. {ECO:0000269|PubMed:21445360}.
null
TRANSMEM 101..121; /note="Helical"; /evidence="ECO:0000255"
PF13180;PF13365;
IPR051201;IPR001478;IPR036034;IPR009003;IPR043504;IPR001940;
1Y8T;2Z9I;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
pepD htrA2 Rv0983
false
Mycobacterium tuberculosis
456
row_5471
false
null
26,785
P9WHH9
MTHYDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGVCLNVGCIPSKALLRNAELVHIFTKDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADANTLLVDLNDGGTESVTFDNAIIATGSSTRLVPGTSLSANVVTYEEQILSRELPKSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTATKVESIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGVDDYMRTNVGHIYAIGDVNGLLQLAHVAEAQGVVAAETIAGAETLTLGDHRMLPRATFCQPNVASFGLTEQQARNEGYDVVVAKFPFTANAKAHGVGDPSGFVKLVADAKHGELLGGHLVGHDVAELLPELTLAQRWDLTASELARNVHTHPTMSEALQECFHGLVGHMINF
Dihydrolipoyl dehydrogenase (LPD) (EC 1.8.1.4) (Component of peroxynitrite reductase/peroxidase complex) (Component of PNR/P) (Dihydrolipoamide dehydrogenase) (E3 component of alpha-ketoacid dehydrogenase complexes)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
464
49,239
3D-structure;Antioxidant;Cytoplasm;Disulfide bond;FAD;Flavoprotein;NAD;Oxidoreductase;Redox-active center;Reference proteome;Virulence
GO:0004148; GO:0005576; GO:0005829; GO:0005886; GO:0006090; GO:0006103; GO:0015036; GO:0016209; GO:0016655; GO:0035375; GO:0045254; GO:0045454; GO:0050660; GO:0070404
Evidence at protein level
5
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
null
null
PF07992;PF02852;
IPR050151;IPR036188;IPR023753;IPR016156;IPR006258;IPR001100;IPR004099;IPR012999;
2A8X;3II4;4M52;7KMY;8CT4;8U0Q;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
lpdC lpd Rv0462 MTV038.06
false
Mycobacterium tuberculosis
457
row_23431
false
null
81,901
P9WP51
MRIAQHISELIGGTPLVRLNSVVPDGAGTVAAKVEYLNPGGSSKDRIAVKMIEAAEASGQLKPGGTIVEPTSGNTGVGLALVAQRRGYKCVFVCPDKVSEDKRNVLIAYGAEVVVCPTAVPPHDPASYYSVSDRLVRDIDGAWKPDQYANPEGPASHYVTTGPEIWADTEGKVTHFVAGIGTGGTITGAGRYLKEVSGGRVRIVGADPEGSVYSGGAGRPYLVEGVGEDFWPAAYDPSVPDEIIAVSDSDSFDMTRRLAREEAMLVGGSCGMAVVAALKVAEEAGPDALIVVLLPDGGRGYMSKIFNDAWMSSYGFLRSRLDGSTEQSTVGDVLRRKSGALPALVHTHPSETVRDAIGILREYGVSQMPVVGAEPPVMAGEVAGSVSERELLSAVFEGRAKLADAVSAHMSPPLRMIGAGELVSAAGKALRDWDALMVVEEGKPVGVITRYDLLGFLSEGAGRR
Probable cystathionine beta-synthase Rv1077 (EC 4.2.1.22) (Beta-thionase) (Serine sulfhydrase)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
464
48,635
3D-structure;Isopeptide bond;Lyase;Pyridoxal phosphate;Reference proteome;Ubl conjugation
GO:0004122; GO:0004124; GO:0005576; GO:0005737; GO:0005886; GO:0006535; GO:0009274; GO:0019343
Evidence at protein level
4
null
null
null
PF00571;PF00291;
IPR046353;IPR000644;IPR046342;IPR050214;IPR005857;IPR001926;IPR036052;
7XNZ;7XOH;7XOY;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
cbs Rv1077
false
Mycobacterium tuberculosis
458
row_72341
false
null
26,354
P95160
MSPQQEPTAQPPRRHRVVIIGSGFGGLNAAKKLKRADVDIKLIARTTHHLFQPLLYQVATGIISEGEIAPPTRVVLRKQRNVQVLLGNVTHIDLAGQCVVSELLGHTYQTPYDSLIVAAGAGQSYFGNDHFAEFAPGMKSIDDALELRGRILSAFEQAERSSDPERRAKLLTFTVVGAGPTGVEMAGQIAELAEHTLKGAFRHIDSTKARVILLDAAPAVLPPMGAKLGQRAAARLQKLGVEIQLGAMVTDVDRNGITVKDSDGTVRRIESACKVWSAGVSASRLGRDLAEQSRVELDRAGRVQVLPDLSIPGYPNVFVVGDMAAVEGVPGVAQGAIQGAKYVASTIKAELAGANPAEREPFQYFDKGSMATVSRFSAVAKIGPVEFSGFIAWLIWLVLHLAYLIGFKTKITTLLSWTVTFLSTRRGQLTITDQQAFARTRLEQLAELAAEAQGSAASAKVAS
Type II NADH:quinone oxidoreductase Ndh (EC 1.6.5.9) (Type II NADH dehydrogenase Ndh)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
463
49,619
3D-structure;Cell inner membrane;Cell membrane;FAD;Flavoprotein;Membrane;NAD;Oxidoreductase;Reference proteome;Transmembrane;Transmembrane helix
GO:0003955; GO:0005886; GO:0019646; GO:0050136
Evidence at protein level
5
SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000269|PubMed:15767566}; Single-pass membrane protein {ECO:0000255}.
null
TRANSMEM 387..407; /note="Helical"; /evidence="ECO:0000255"
PF07992;
IPR036188;IPR023753;IPR045024;
9MQY;9MQZ;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
ndh Rv1854c
false
Mycobacterium tuberculosis
459
row_23069
false
null
26,715
P9WFV7
MHHPVAPVIDTVVNLAKRRGFVYPSGEIYGGTKSAWDYGPLGVELKENIKRQWWRSVVTGRDDVVGIDSSIILPREVWVASGHVDVFHDPLVESLITHKRYRADHLIEAYEAKHGHPPPNGLADIRDPETGEPGQWTQPREFNMMLKTYLGPIETEEGLHYLRPETAQGIFVNFANVVTTARKKPPFGIGQIGKSFRNEITPGNFIFRTREFEQMEMEFFVEPATAKEWHQYWIDNRLQWYIDLGIRRENLRLWEHPKDKLSHYSDRTVDIEYKFGFMGNPWGELEGVANRTDFDLSTHARHSGVDLSFYDQINDVRYTPYVIEPAAGLTRSFMAFLIDAYTEDEAPNTKGGMDKRTVLRLDPRLAPVKAAVLPLSRHADLSPKARDLGAELRKCWNIDFDDAGAIGRRYRRQDEVGTPFCVTVDFDSLQDNAVTVRERDAMTQDRVAMSSVADYLAVRLKGS
Glycine--tRNA ligase (EC 6.1.1.14) (Glycyl-tRNA synthetase) (GlyRS)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
463
52,938
3D-structure;Acetylation;Aminoacyl-tRNA synthetase;ATP-binding;Cytoplasm;Ligase;Nucleotide-binding;Protein biosynthesis;Reference proteome
GO:0004081; GO:0004820; GO:0005524; GO:0005737; GO:0005829; GO:0005886; GO:0006418; GO:0006426; GO:0015966; GO:0046983; GO:0070062; GO:1903561; GO:1990742
Evidence at protein level
5
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00253}.
null
null
PF03129;PF00587;
IPR002314;IPR006195;IPR045864;IPR004154;IPR036621;IPR027031;IPR022961;IPR033731;IPR002315;
8T5N;8U2P;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
glyQS glyS Rv2357c MTCY27.23 MTCY98.26
false
Mycobacterium tuberculosis
460
row_23362
false
null
26,891
P9WKC9
MNHLTTLDAGFLKAEDVDRHVSLAIGALAVIEGPAPDQEAFLSSLAQRLRPCTRFGQRLRLRPFDLGAPKWVDDPDFDLGRHVWRIALPRPGNEDQLFELIADLMARRLDRGRPLWEVWVIEGLADSKWAILTKLHHCMADGIAATHLLAGLSDESMSDSFASNIHTTMQSQSASVRRGGFRVNPSEALTASTAVMAGIVRAAKGASEIAAGVLSPAASSLNGPISDLRRYSAAKVPLADVEQVCRKFDVTINDVALAAITESYRNVLIQRGERPRFDSLRTLVPVSTRSNSALSKTDNRVSLMLPNLPVDQENPLQRLRIVHSRLTRAKAGGQRQFGNTLMAIANRLPFPMTAWAVGLLMRLPQRGVVTVATNVPGPRRPLQIMGRRVLDLYPVSPIAMQLRTSVAMLSYADDLYFGILADYDVVADAGQLARGIEDAVARLVAISKRRKVTRRRGALSLVV
Probable diacyglycerol O-acyltransferase tgs1 (TGS1) (EC 2.3.1.20) (Probable triacylglycerol synthase tgs1)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
463
50,721
Acetylation;Acyltransferase;Glycerol metabolism;Lipid biosynthesis;Lipid metabolism;Reference proteome;Transferase
GO:0001666; GO:0004144; GO:0005886; GO:0006071; GO:0008374; GO:0009274; GO:0019432; GO:0045017; GO:0047196; GO:0051701; GO:0071731
Evidence at protein level
5
null
null
null
PF06974;PF03007;
IPR014292;IPR045034;IPR009721;IPR004255;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
tgs1 Rv3130c MTCY03A2.28 MTCY164.41c
false
Mycobacterium tuberculosis
461
row_23532
false
null
81,778
P9WJI7
MAIRQHVGALFTDLYEVTMAQAYWAERMSGTAVFEIFFRKLPPGRSYIMAAGLADVVEFLEAFRFDEQDLRYLRGLGQFSDEFLRWLAGVRFTGDVWAAPEGTVIFPNEPAVQLIAPIIEAQLVETFVLNQIHLQSVLASKAARVVAAARGRPVVDFGARRAHGTDAACKVARTSYLAGAAGTSNLLAARQYGIPTFGTMAHSFVQAFDSEVAAFEAFARLYPATMLLVDTYDTLRGVDHVIELAKRLGNRFDVRAVRLDSGDLDELSKATRARLDTAGLEQVEIFASSGLDENRIAALLAARCPIDGFGVGTQLVVAQDAPALDMAYKLVAYDGSGRTKFSSGKVIYPGRKQVFRKLEHGVFCGDTLGEHGENLPGDPLLVPIMTNGRRIRQHAPTLDGARDWARQQIDALPPELRSLEDTGYSYPVAVSDRIVGELARLRHADTAEAHPGSNVVGAKAKRP
Nicotinate phosphoribosyltransferase pncB2 (NAPRTase pncB2) (EC 6.3.4.21)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
463
50,509
Ligase;Phosphoprotein;Pyridine nucleotide biosynthesis;Reference proteome;Transferase
GO:0001666; GO:0004516; GO:0005829; GO:0005886; GO:0009435; GO:0034355; GO:0047280; GO:0075136
Evidence at protein level
4
null
null
null
PF04095;PF17767;
IPR013785;IPR041525;IPR040727;IPR007229;IPR006405;IPR036068;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
pncB2 Rv0573c
false
Mycobacterium tuberculosis
462
row_72225
false
null
212,999
P9WNL3
MTQDGTWVDESDWQLDDSEIAESGAAPVVAVVGRPNVGKSTLVNRILGRREAVVQDIPGVTRDRVCYDALWTGRRFVVQDTGGWEPNAKGLQRLVAEQASVAMRTADAVILVVDAGVGATAADEAAARILLRSGKPVFLAANKVDSEKGESDAAALWSLGLGEPHAISAMHGRGVADLLDGVLAALPEVGESASASGGPRRVALVGKPNVGKSSLLNKLAGDQRSVVHEAAGTTVDPVDSLIELGGDVWRFVDTAGLRRKVGQASGHEFYASVRTHAAIDSAEVAIVLIDASQPLTEQDLRVISMVIEAGRALVLAYNKWDLVDEDRRELLQREIDRELVQVRWAQRVNISAKTGRAVHKLVPAMEDALASWDTRIATGPLNTWLTEVTAATPPPVRGGKQPRILFATQATARPPTFVLFTTGFLEAGYRRFLERRLRETFGFDGSPIRVNVRVREKRAGKRR
GTPase Der (GTP-binding protein EngA)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
463
49,958
GTP-binding;Nucleotide-binding;Reference proteome;Repeat;Ribosome biogenesis
GO:0005525; GO:0005886; GO:0009274; GO:0016887; GO:0042254; GO:0043022
Evidence at protein level
3
null
null
null
PF14714;PF01926;
IPR003593;IPR031166;IPR006073;IPR016484;IPR032859;IPR015946;IPR027417;IPR005225;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
der engA Rv1713 MTCI125.35
false
Mycobacterium tuberculosis
463
row_199200
false
null
431,475
P9WI48
MAIPPEVHSGLLSAGCGPGSLLVAAQQWQELSDQYALACAELGQLLGEVQASSWQGTAATQYVAAHGPYLAWLEQTAINSAVTAAQHVAAAAAYCSALAAMPTPAELAANHAIHGVLIATNFFGINTVPIALNEADYVRMWLQAADTMAAYQAVADAATVAVPSTQPAPPIRAPGGDAADTRLDVLSSIGQLIRDILDFIANPYKYFLEFFEQFGFSPAVTVVLALVALQLYDFLWYPYYASYGLLLLPFFTPTLSALTALSALIHLLNLPPAGLLPIAAALGPGDQWGANLAVAVTPATAAVPGGSPPTSNPAPAAPSSNSVGSASAAPGISYAVPGLAPPGVSSGPKAGTKSPDTAADTLATAGAARPGLARAHRRKRSESGVGIRGYRDEFLDATATVDAATDVPAPANAAGSQGAGTLGFAGTAPTTSGAAAGMVQLSSHSTSTTVPLLPTTWTTDAEQ
Uncharacterized PPE family protein PPE1
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
83,331
463
46,895
Cell membrane;Membrane;Reference proteome;Transmembrane;Transmembrane helix
GO:0005886; GO:0052572
Inferred from homology
2
SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
null
TRANSMEM 3..23; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 88..108; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 112..132; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 216..236; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 245..265; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 276..296; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 323..343; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 419..439; /note="Helical"; /evidence="ECO:0000255"
PF00823;PF18878;
IPR043641;IPR000030;IPR038332;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
PPE1 MT0105
false
Mycobacterium tuberculosis
464
row_413234
false
null
431,511
P9WIF9
MSYMIAVPDMLSSAAGDLASIGSSINASTRAAAAATTRLLPAAADEVSAHIAALFSGHGEGYQAIARQMAAFHDQFTLALTSSAGAYASAEATNVEQQVLGLINAPTQALLGRPLIGNGADGTAANPNGGAGGLLYGNGGNGFSQTTAGLTGGTGGSAGLIGNGGNGGAGGAGANGGAGGNGGWLYGSGGNGGAGGAGPAGAIGAPGVAGGAGGAGGTAGLFGNGGAGGAGGAGGAGGRGGDGGSAGWLSGNGGDAGTGGGGGNAGNGGNGGSAGWLSGNGGTGGGGGTAGAGGQGGNGNSGIDPGNGGQGADTGNAGNGGHGGSAAKLFGDGGAGGAGGMGSTGGTGGGGGFGGGTGGNGGNGHAGGAGGSGGTAGLLGSGGSGGTGGDGGNGGLGAGSGAKGNGGNGGDGGKGGDAQLIGNGGNGGNGGKGGTGLMPGINGTGGAGGSRGQISGNPGTPGQ
Uncharacterized PE-PGRS family protein PE_PGRS20
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
463
39,305
Reference proteome
null
Inferred from homology
2
null
null
null
PF00934;PF21526;
IPR000084;IPR048996;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
PE_PGRS20 Rv1068c MTV017.21c
false
Mycobacterium tuberculosis
465
row_413270
false
null
539,518
P0A693
MDFGVLPPEINSGRMYAGPGSGPMLAAAAAWDGLATELQSTAADYGSVISVLTGVWSGQSSGTMAAAAAPYVAWMSATAALAREAAAQASAAAAAYEAAFAATVPPPVVAANRAELAVLAATNIFGQNTGAIAAAEARYAEMWAQDAAAMYGYAGSSSVATQVTPFAAPPPTTNAAGLATQGVAVAQAVGASAGNARSLVSEVLEFLATAGTNYNKTVASLMNAVTGVPYASSVYNSMLGLGFAESKMVLPANDTVISTIFGMVQFQKFFNPVTPFNPDLIPKSALGAGLGLRSAISSGLGSTAPAISAGASQAGSVGGMSVPPSWAAATPAIRTVAAVFSSTGLQAVPAAAISEGSLLSQMALASVAGGALGGAAARATGGFLGGGRVTAVKKSLKDSDSPDKLRRVVAHMMEKPESVQHWHTDEDGLDDLLAELKKKPGIHAVHMAGGNKAEIAPTISESG
Uncharacterized PPE family protein PPE30
Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
233,413
463
46,021
Reference proteome
GO:0052572
Inferred from homology
1
null
null
null
PF00823;PF12484;
IPR022171;IPR000030;IPR038332;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype)
PPE30 BQ2027_MB1830
false
Mycobacterium tuberculosis
466
row_519807
false
null
4,636
O07732
MAQAPHIHRTRYAKCGDMDIAYQVLGDGPTDLLVLPGPFVPIDSIDDEPSLYRFHRRLASFSRVIRLDHRGVGLSSRLAAITTLGPKFWAQDAIAVMDAVGCEQATIFAPSFHAMNGLVLAADYPERVRSLIVVNGSARPLWAPDYPVGAQVRRADPFLTVALEPDAVERGFDVLSIVAPTVAGDDVFRAWWDLAGNRAGPPSIARAVSKVIAEADVRDVLGHIEAPTLILHRVGSTYIPVGHGRYLAEHIAGSRLVELPGTDTLYWVGDTGPMLDEIEEFITGVRGGADAERMLATIMFTDIVGSTQHAAALGDDRWRDLLDNHDTIVCHEIQRFGGREVNTAGDGFVATFTSPSAAIACADDIVDAVAALGIEVRIGIHAGEVEVRDASHGTDVAGVAVHIGARVCALAGPSEVLVSSTVRDIVAGSRHRFAERGEQELKGVPGRWRLCVLMRDDATRTR
Bifunctional lipase/adenylate cyclase LipJ [Includes: Lipase (EC 3.1.1.-); Adenylate cyclase (EC 4.6.1.1) (Adenylyl cyclase)]
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
462
49,716
3D-structure;Hydrolase;Lipid metabolism;Lyase;Manganese;Metal-binding;Multifunctional enzyme;Reference proteome
GO:0004016; GO:0006171; GO:0006629; GO:0016787; GO:0030145; GO:0035556; GO:0042803
Evidence at protein level
5
null
null
null
PF00561;PF00211;
IPR001054;IPR050471;IPR000073;IPR029058;IPR029787;
1YBT;1YBU;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
lipJ Rv1900c
false
Mycobacterium tuberculosis
467
row_3716
false
null
6,623
O53512
MNWTVDIPIDQLPSLPPLPTDLRTRLDAALAKPAAQQPTWPADQALAMRTVLESVPPVTVPSEIVRLQEQLAQVAKGEAFLLQGGDCAETFMDNTEPHIRGNVRALLQMAVVLTYGASMPVVKVARIAGQYAKPRSADIDALGLRSYRGDMINGFAPDAAAREHDPSRLVRAYANASAAMNLVRALTSSGLASLHLVHDWNREFVRTSPAGARYEALATEIDRGLRFMSACGVADRNLQTAEIYASHEALVLDYERAMLRLSDGDDGEPQLFDLSAHTVWIGERTRQIDGAHIAFAQVIANPVGVKLGPNMTPELAVEYVERLDPHNKPGRLTLVSRMGNHKVRDLLPPIVEKVQATGHQVIWQCDPMHGNTHESSTGFKTRHFDRIVDEVQGFFEVHRALGTHPGGIHVEITGENVTECLGGAQDISETDLAGRYETACDPRLNTQQSLELAFLVAEMLRD
Phospho-2-dehydro-3-deoxyheptonate aldolase AroG (EC 2.5.1.54) (3-deoxy-D-arabino-heptulosonate 7-phosphate synthase) (DAHP synthase) (Phospho-2-keto-3-deoxyheptonate aldolase)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
462
50,641
3D-structure;Amino-acid biosynthesis;Aromatic amino acid biosynthesis;Cadmium;Cobalt;Manganese;Metal-binding;Reference proteome;Transferase
GO:0003849; GO:0005829; GO:0005886; GO:0008652; GO:0009073; GO:0009274; GO:0009423; GO:0030145; GO:0051260
Evidence at protein level
5
null
null
null
PF01474;
IPR013785;IPR002480;
2B7O;2W19;2W1A;2YPO;2YPP;2YPQ;3KGF;3NUD;3NUE;3NV8;3PFP;3RZI;5CKV;5CKX;5E2L;5E40;5E4N;5E5G;5E7Z;5EX4;6PBJ;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
aroG Rv2178c
false
Mycobacterium tuberculosis
468
row_5457
false
null
112,135
A1KG00
MGSTEQATSRVRGAARTSAQLFEAACSVIPGGVNSPVRAFTAVGGTPRFITEAHGCWLIDADGNRYVDLVCSWGPMILGHAHPAVVEAVAKAAARGLSFGAPTPAETQLAGEIIGRVAPVERIRLVNSGTEATMSAVRLARGFTGRAKIVKFSGCYHGHVDALLADAGSGVATLGLCDDPQRPASPRSQSSRGLPSSPGVTGAAAADTIVLPYNDIDAVQQTFARFGEQIAAVITEASPGNMGVVPPGPGFNAALRAITAEHGALLILDEVMTGFRVSRSGWYGIDPVPADLFAFGKVMSGGMPAAAFGGRAEVMQRLAPLGPVYQAGTLSGNPVAVAAGLATLRAADDAVYTALDANADRLAGLLSEALTDAVVPHQISRAGNMLSVFFGETPVTDFASARASQTWRYPAFFHAMLDAGVYPPCSAFEAWFVSAALDDAAFGRIANALPAAARAAAQERPA
Glutamate-1-semialdehyde 2,1-aminomutase (GSA) (EC 5.4.3.8) (Glutamate-1-semialdehyde aminotransferase) (GSA-AT)
Mycobacterium bovis (strain BCG / Pasteur 1173P2)
410,289
462
47,516
Cytoplasm;Isomerase;Porphyrin biosynthesis;Pyridoxal phosphate
GO:0005737; GO:0006782; GO:0008483; GO:0030170; GO:0042286
Inferred from homology
3
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00375}.
null
null
PF00202;
IPR004639;IPR005814;IPR049704;IPR015424;IPR015421;IPR015422;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype), Mycobacterium tuberculosis variant bovis BCG (no rank)
hemL BCG_0567
false
Mycobacterium tuberculosis
469
row_100602
false
null
212,677
P9WJE9
MRNPLGLRFSTGHALLASALAPPCIIAFLETRYWWAGIALASLGVIVATVTFYGRRITGWVAAVYAWLRRRRRPPDSSSEPVVGATVKPGDHVAVRWQGEFLVAVIELIPRPFTPTVIVDGQAHTDDMLDTGLVEELLSVHCPDLEADIVSAGYRVGNTAAPDVVSLYQQVIGTDPAPANRRTWIVLRADPERTRKSAQRRDEGVAGLARYLVASATRIADRLASHGVDAVCGRSFDDYDHATDIGFVREKWSMIKGRDAYTAAYAAPGGPDVWWSARADHTITRVRVAPGMAPQSTVLLTTADKPKTPRGFARLFGGQRPALQGQHLVANRHCQLPIGSAGVLVGETVNRCPVYMPFDDVDIALNLGDAQTFTQFVVRAAAAGAMVTVGPQFEEFARLIGAHIGQEVKVAWPNATTYLGPHPGIDRVILRHNVIGTPRHRQLPIRRVSPPEESRYQMALPK
ESX-1 secretion system protein EccE1 (ESX conserved component E1) (Type VII secretion system protein EccE1) (T7SS protein EccE1)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
462
50,397
Cell inner membrane;Cell membrane;Membrane;Reference proteome;Transmembrane;Transmembrane helix;Transport
GO:0005886
Evidence at protein level
3
SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000255}.
null
TRANSMEM 9..29; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 34..54; /note="Helical"; /evidence="ECO:0000255"
PF11203;
IPR050051;IPR021368;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
eccE1 snm7 Rv3882c
false
Mycobacterium tuberculosis
470
row_198884
false
null
425,358
P63493
MDPTDLAFAGAAAQARMLADGALTAPMLLEVYLQRIERLDSHLRAYRVVQFDRARAEAEAAQQRLDAGERLPLLGVPIAIKDDVDIAGEVTTYGSAGHGPAATSDAEVVRRLRAAGAVIIGKTNVPELMIMPFTESLAFGATRNPWCLNRTPGGSSGGSAAAVAAGLAPVALGSDGGGSIRIPCTWCGLFGLKPQRDRISLEPHDGAWQGLSVNGPIARSVMDAALLLDATTTVPGPEGEFVAAAARQPGRLRIALSTRVPTPLPVRCGKQELAAVHQAGALLRDLGHDVVVRDPDYPASTYANYLPRFFRGISDDADAQAHPDRLEARTRAIARLGSFFSDRRMAALRAAEVVLSSRIQSIFDDVDVVVTPGAATGPSRIGAYQRRGAVSTLLLVVQRVPYFQVWNLTGQPAAVVPWDFDGDGLPMSVQLVGRPYDEATLLALAAQIESARPWAHRRPSVS
Putative amidase AmiB2 (EC 3.5.1.4)
Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
233,413
462
49,081
Hydrolase;Reference proteome
GO:0004040
Inferred from homology
2
null
null
null
PF01425;
IPR000120;IPR020556;IPR023631;IPR036928;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype)
amiB2 BQ2027_MB1294
false
Mycobacterium tuberculosis
471
row_407459
false
null
26,862
P9WJF1
MLSVGATTTATRLTGWGRTAPSVANVLRTPDAEMIVKAVARVAESGGGRGAIARGLGRSYGDNAQNGGGLVIDMTPLNTIHSIDADTKLVDIDAGVNLDQLMKAALPFGLWVPVLPGTRQVTVGGAIACDIHGKNHHSAGSFGNHVRSMDLLTADGEIRHLTPTGEDAELFWATVGGNGLTGIIMRATIEMTPTSTAYFIADGDVTASLDETIALHSDGSEARYTYSSAWFDAISAPPKLGRAAVSRGRLATVEQLPAKLRSEPLKFDAPQLLTLPDVFPNGLANKYTFGPIGELWYRKSGTYRGKVQNLTQFYHPLDMFGEWNRAYGPAGFLQYQFVIPTEAVDEFKKIIGVIQASGHYSFLNVFKLFGPRNQAPLSFPIPGWNICVDFPIKDGLGKFVSELDRRVLEFGGRLYTAKDSRTTAETFHAMYPRVDEWISVRRKVDPLRVFASDMARRLELL
Decaprenylphosphoryl-beta-D-ribose oxidase (EC 1.1.98.3) (Decaprenylphospho-beta-D-ribofuranose 2-dehydrogenase) (Decaprenylphosphoryl-beta-D-ribofuranose 2'-epimerase subunit DprE1) (Decaprenyl-phosphoribose 2'-epimerase subunit 1) (Decaprenylphosphoryl-beta-D-ribofuranose 2'-oxidase) (Decaprenylphosphoryl-beta-D-ribose 2-epimerase flavoprotein subunit) (FAD-dependent decaprenylphosphoryl-beta-D-ribofuranose 2-oxidase)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
461
50,163
3D-structure;Antibiotic resistance;Cell wall biogenesis/degradation;FAD;Flavoprotein;Oxidoreductase;Periplasm;Reference proteome
GO:0003885; GO:0005886; GO:0016491; GO:0035884; GO:0042597; GO:0045227; GO:0046677; GO:0070592; GO:0071555; GO:0071949
Evidence at protein level
5
SUBCELLULAR LOCATION: Periplasm {ECO:0000269|PubMed:25906160}.
null
null
PF04030;PF01565;
IPR007173;IPR016166;IPR036318;IPR016169;IPR010031;IPR006094;
4FDN;4FDO;4FDP;4FEH;4FF6;4KW5;4NCR;4P8C;4P8H;4P8K;4P8L;4P8M;4P8N;4P8P;4P8T;4P8Y;4PFA;4PFD;5OEL;5OEP;5OEQ;6G83;6HEZ;6HF0;6HF3;6HFV;6HFW;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
dprE1 Rv3790
false
Mycobacterium tuberculosis
472
row_23505
false
null
39,864
Q79FC3
MSFVNVAPQLVSTAAADAARIGSAINTANTAAAATTQVLAAAQDEVSTAIAALFGSHGQHYQAISAQVAAYQQRFVLALSQAGSTYAVAEAASATPLQNVLDAINAPVQSLTGRPLIGDGANGIDGTGQAGGNGGWLWGNGGNGGSGAPGQAGGAGGAAGLIGNGGAGGAGGQGLPFEAGANGGAGGAGGWLFGNGGAGGNGGIGGAGTNLAIGGHGGNGGNAGLIGAGGTGGAGGTGGGEPSAGASGGNGGNGGNGGLLIGNSGDGGAAGNGAGISQNGPASGFGGNGGHAGTTGLIGNGGNGGAGGAGGDVSADFGGVGFGGQGGNGGAGGLLYGNGGAGGNGGAAGSPGSVTAFGGNGGSGGSGGNGGNALIGNAGAGGSAGAGGNGASAGTAGGSGGDGGKGGNGGSVGLIGNGGNGGNGGAGSLFNGAPGFGGPGGSGGASLLGPPGLAGTNGADG
PE-PGRS family protein PE_PGRS45 (NADPH dependent oxido-reductase) (NADPH-dependent fatty acyl-CoA reductase) (EC 1.2.1.n2)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
461
39,311
Cell membrane;Cell wall;Host mitochondrion;Membrane;Oxidoreductase;Reference proteome;Secreted;Virulence
GO:0005576; GO:0005886; GO:0016491; GO:0033650
Evidence at protein level
5
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:36448553}. Secreted, cell wall {ECO:0000269|PubMed:36448553}. Host mitochondrion {ECO:0000269|PubMed:37565603}. Note=When expressed in M.smegmatis, is predominantly localized in the cell wall and cytoplasmic membrane fractions (PubMed:36448553). Trace amount of protein is also detected in the cytosolic fraction (PubMed:36448553). Localizes within mitochondria of THP1 macrophages (PubMed:37565603). {ECO:0000269|PubMed:36448553, ECO:0000269|PubMed:37565603}.
null
null
PF00934;PF21526;
IPR000084;IPR048996;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
PE_PGRS45 Rv2615c
false
Mycobacterium tuberculosis
473
row_34468
false
null
182,383
O06380
MGPTRWRKSTHVVVGAAVLAFVAVVVAAAALVTTGGHRAGVRAPAPPPRPPTVKAGVVPVADTAATPSAAGVTAALAVVAADPDLGKLAGRITDALTGQELWQRLDDVPLVPASTNKILTAAAALLTLDRQARISTRVVAGGQNPQGPVVLVGAGDPTLSAAPPGQDTWYHGAARIGDLVEQIRRSGVTPTAVQVDASAFSGPTMAPGWDPADIDNGDIAPIEAAMIDAGRIQPTTVNSRRSRTPALDAGRELAKALGLDPAAVTIASAPAGARQLAVVQSAPLIQRLSQMMNASDNVMAECIGREVAVAINRPQSFSGAVDAVTSRLNTAHIDTAGAALVDSSGLSLDNRLTARTLDATMQAAAGPDQPALRPLLDLLPIAGGSGTLGERFLDAATDQGPAGWLRAKTGSLTAINSLVGVLTDRSGRVLTFAFISNEAGPNGRNAMDALATKLWFCGCTT
Carboxypeptidase Rv3627c (EC 3.4.16.-)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
461
46,834
Carboxypeptidase;Cell wall biogenesis/degradation;Hydrolase;Protease;Reference proteome;Signal
GO:0000270; GO:0004185; GO:0005576; GO:0006508; GO:0071555
Evidence at protein level
3
null
SIGNAL 1..28; /evidence="ECO:0000255"
null
PF02113;PF23714;
IPR012338;IPR000667;IPR056340;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
Rv3627c
false
Mycobacterium tuberculosis
474
row_169403
false
null
185,404
O53695
MIRAAFACLAATVVVAGWWTPPAWAIGPPVVDAAAQPPSGDPGPVAPMEQRGACSVSGVIPGTDPGVPTPSQTMLNLPAAWQFSRGEGQLVAIIDTGVQPGPRLPNVDAGGDFVESTDGLTDCDGHGTLVAGIVAGQPGNDGFSGVAPAARLLSIRAMSTKFSPRTSGGDPQLAQATLDVAVLAGAIVHAADLGAKVINVSTITCLPADRMVDQAALGAAIRYAAVDKDAVIVAAAGNTGASGSVSASCDSNPLTDLSRPDDPRNWAGVTSVSIPSWWQPYVLSVASLTSAGQPSKFSMPGPWVGIAAPGENIASVSNSGDGALANGLPDAHQKLVALSGTSYAAGYVSGVAALVRSRYPGLNATEVVRRLTATAHRGARESSNIVGAGNLDAVAALTWQLPAEPGGGAAPAKPVADPPVPAPKDTTPRNVAFAGAAALSVLVGLTAATVAIARRRREPTE
Mycosin-3 (EC 3.4.21.-) (MycP3 protease)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
461
46,127
Cell membrane;Hydrolase;Membrane;Protease;Reference proteome;Serine protease;Signal;Transmembrane;Transmembrane helix
GO:0004252; GO:0005576; GO:0005886; GO:0009274; GO:0016485
Evidence at protein level
3
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:10974545}; Single-pass membrane protein {ECO:0000255}. Note=Cell wall-associated. {ECO:0000269|PubMed:10974545}.
SIGNAL 1..25; /evidence="ECO:0000255"
TRANSMEM 432..452; /note="Helical"; /evidence="ECO:0000255"
PF00082;
IPR000209;IPR036852;IPR022398;IPR015500;IPR023834;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
mycP3 Rv0291
false
Mycobacterium tuberculosis
475
row_172363
false
null
424,354
P59954
MATATTQRPLKGPAKRMSTWTMTREAITIGFDAGDGFLGRLRGSDITRFRCAGRRFVSISHPDYVDHVLHEARLKYVKSDEYGPIRATAGLNLLTDEGDSWARHRGALNSTFARRHLRGLVGLMIDPIADVTAALVPGAQFDMHQSMVETTLRVVANALFSQDFGPLVQSMHDLATRGLRRAEKLERLGLWGLMPRTVYDTLIWCIYSGVHLPPPLREMQEITLTLDRAINSVIDRRLAEPTNSADLLNVLLSADGGIWPRQRVRDEALTFMLAGHETTANAMSWFWYLMALNPQARDHMLTELDDVLGMRRPTADDLGKLAWTTACLQESQRYFSSVWIIAREAVDDDIIDGHRIRRGTTVVIPIHHIHHDPRWWPDPDRFDPGRFLRCPTDRPRCAYLPFGGGRRICIGQSFALMEMVLMAAIMSQHFTFDLAPGYHVELEATLTLRPKHGVHVIGRRR
Putative cytochrome P450 132 (EC 1.14.-.-)
Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
233,413
461
52,186
Heme;Iron;Metal-binding;Monooxygenase;Oxidoreductase;Reference proteome
GO:0004497; GO:0005506; GO:0016705; GO:0020037
Inferred from homology
2
null
null
null
PF00067;
IPR001128;IPR017972;IPR002401;IPR036396;IPR050196;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype)
cyp132 BQ2027_MB1429C
false
Mycobacterium tuberculosis
476
row_406468
false
null
426,694
P66774
MTISVFDLFTIGIGPSSSHTVGPMRAANQFVVALRRRGHLDDLEAMRVDLFGSLAATGAGHGTMSAILLGLEGCQPETITTEHKERRLAEIAASGVTRIGGVIPVPLTERDIDLHPDIVLPTHPNGMTFTAAGPHGRVLATETYFSVGGGFIVTEQTSGNSGQHPCSVALPYVSAQELLDICDRLDVSISEAALRNETCCRTENEVRAALLHLRDVMVECEQRSIAREGLLPGGLRVRRRAKVWYDRLNAEDPTRKPEFAEDWVNLVALAVNEENASGGRVVTAPTNGAAGIVPAVLHYAIHYTSAGAGDPDDVTVRFLLTAGAIGSLFKERASISGAEVGCQGEVGSAAAMAAAGLAEILGGTPRQVENAAEIAMEHSLGLTCDPIAGLVQIPCIERNAISAGKAINAARMALRGDGIHRVTLDQVIDTMRATGADMHTKYKETSAGGLAINVAVNIVEC
L-serine dehydratase (SDH) (EC 4.3.1.17) (L-serine deaminase) (L-SD)
Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
233,413
461
48,576
4Fe-4S;Gluconeogenesis;Iron;Iron-sulfur;Lyase;Metal-binding;Reference proteome
GO:0003941; GO:0006094; GO:0046872; GO:0051539
Inferred from homology
2
null
null
null
PF03313;PF03315;
IPR029009;IPR051318;IPR004644;IPR005130;IPR005131;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype)
sdaA BQ2027_MB0070C
false
Mycobacterium tuberculosis
477
row_408788
false
null
26,860
P9WJD9
MTQSQTVTVDQQEILNRANEVEAPMADPPTDVPITPCELTAAKNAAQQLVLSADNMREYLAAGAKERQRLATSLRNAAKAYGEVDEEAATALDNDGEGTVQAESAGAVGGDSSAELTDTPRVATAGEPNFMDLKEAARKLETGDQGASLAHFADGWNTFNLTLQGDVKRFRGFDNWEGDAATACEASLDQQRQWILHMAKLSAAMAKQAQYVAQLHVWARREHPTYEDIVGLERLYAENPSARDQILPVYAEYQQRSEKVLTEYNNKAALEPVNPPKPPPAIKIDPPPPPQEQGLIPGFLMPPSDGSGVTPGTGMPAAPMVPPTGSPGGGLPADTAAQLTSAGREAAALSGDVAVKAASLGGGGGGGVPSAPLGSAIGGAESVRPAGAGDIAGLGQGRAGGGAALGGGGMGMPMGAAHQGQGGAKSKGSQQEDEALYTEDRAWTEAVIGNRRRQDSKESK
ESX-1 secretion-associated protein EspB (Antigen MTB48)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
460
47,594
3D-structure;Acetylation;Direct protein sequencing;Reference proteome;Secreted;Virulence
GO:0005576; GO:0042802; GO:0044315; GO:0051701; GO:0140321
Evidence at protein level
5
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:17676952, ECO:0000269|PubMed:23869560}. Note=Secreted via the ESX-1 / type VII secretion system (T7SS) (PubMed:17676952). Secretion requires both EspK and EccCb1, but not EspA, EspC and EspD (PubMed:17676952, PubMed:23869560). {ECO:0000269|PubMed:17676952, ECO:0000269|PubMed:23869560}.
null
null
PF18625;PF21856;
IPR041275;IPR054056;IPR038332;
3J83;4XWP;4XXN;4XXX;4XY3;6XZC;7P13;8AKO;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
espB mtb48 Rv3881c MTV027.16c
false
Mycobacterium tuberculosis
478
row_23503
false
null
212,832
P9WL37
MMARLKVPEGWCVQAFRFTLNPTQTQAASLARHFGARRKAFNWTVTALKADIKAWRADGTESAKPSLRVLRKRWNTVKDQVCVNAQTGQVWWPECSKEAYADGIAGAVDAYWNWQSCRAGKRAGKTVGVPRFKKKGRDADRVCFTTGAMRVEPDRRHLTLPVIGTIRTYENTRRVERLIAKGRARVLAITVRRNGTRLDASVRVLVQRPQQRRVALPDSRVGVDVGVRRLATVADAEGTVLEQVPNPRPLDAALRGLRRVSRARSRCTKGSRRYCERTTELSRLHRRVNDVRTHHLHVLTTRLAKTHGRIVVEGLDAAGMLRQKGLPGARARRRALSDAALATPRRHLSYKTGWYGSSLVVADRWFPSSKTCHACRHVQDIGWDEKWQCDGCSITHQRDDNAAINLARYEEPPSVVGPVGAAVKRGADRKTGPGPAGGREARKATGHPAGEQPRDGVQVK
Putative RNA-guided DNA endonuclease Rv2885c (EC 3.1.21.-)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
460
51,284
DNA recombination;DNA-binding;Endonuclease;Hydrolase;Metal-binding;Nuclease;Reference proteome;Transposable element;Transposition;Zinc
GO:0003677; GO:0004519; GO:0005886; GO:0006310; GO:0032196; GO:0046872
Inferred from homology
3
null
null
null
PF07282;PF12323;PF01385;
IPR010095;IPR053470;IPR001959;IPR021027;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
Rv2885c MTCY274.16c
false
Mycobacterium tuberculosis
479
row_199036
false
null
26,783
P9WHH3
METYDIAIIGTGSGNSILDERYASKRAAICEQGTFGGTCLNVGCIPTKMFVYAAEVAKTIRGASRYGIDAHIDRVRWDDVVSRVFGRIDPIALSGEDYRRCAPNIDVYRTHTRFGPVQADGRYLLRTDAGEEFTAEQVVIAAGSRPVIPPAILASGVDYHTSDTVMRIAELPEHIVIVGSGFIAAEFAHVFSALGVRVTLVIRGSCLLRHCDDTICERFTRIASTKWELRTHRNVVDGQQRGSGVALRLDDGCTINADLLLVATGRVSNADLLDAEQAGVDVEDGRVIVDEYQRTSARGVFALGDVSSPYLLKHVANHEARVVQHNLLCDWEDTQSMIVTDHRYVPAAVFTDPQIAAVGLTENQAVAKGLDISVKIQDYGDVAYGWAMEDTSGIVKLITERGSGRLLGAHIMGYQASSLIQPLIQAMSFGLTAAEMARGQYWIHPALPEVVENALLGLR
Mycothione reductase (EC 1.8.1.15) (Mycothiol-disulfide reductase) (NADPH-dependent mycothione reductase)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
459
49,946
Direct protein sequencing;Disulfide bond;FAD;Flavoprotein;NAD;NADP;Oxidoreductase;Redox-active center;Reference proteome
GO:0004148; GO:0005829; GO:0006090; GO:0006103; GO:0010126; GO:0050627; GO:0050660; GO:0070402
Evidence at protein level
5
null
null
null
PF07992;PF02852;
IPR050151;IPR036188;IPR023753;IPR016156;IPR017817;IPR001100;IPR004099;IPR012999;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
mtr gorA Rv2855
false
Mycobacterium tuberculosis
480
row_23429
false
null
212,637
P9WIT1
MSEMTARFSEIVGNANLLTGDAIPEDYAHDEELTGPPQKPAYAAKPATPEEVAQLLKAASENGVPVTARGSGCGLSGAARPVEGGLLISFDRMNKVLEVDTANQVAVVQPGVALTDLDAATADTGLRYTVYPGELSSSVGGNVGTNAGGMRAVKYGVARHNVLGLQAVLPTGEIIRTGGRMAKVSTGYDLTQLIIGSEGTLALVTEVIVKLHPRLDHNASVLAPFADFDQVMAAVPKILASGLAPDILEYIDNTSMAALISTQNLELGIPDQIRDSCEAYLLVALENRIADRLFEDIQTVGEMLMELGAVDAYVLEGGSARKLIEAREKAFWAAKALGADDIIDTVVPRASMPKFLSTARGLAAAADGAAVGCGHAGDGNVHMAIACKDPEKKKKLMTDIFALAMELGGAISGEHGVGRAKTGYFLELEDPVKISLMRRIKQSFDPAGILNPGVVFGDT
Uncharacterized FAD-linked oxidoreductase Rv2280 (EC 1.-.-.-)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
459
48,052
FAD;Flavoprotein;Isopeptide bond;Oxidoreductase;Reference proteome;Ubl conjugation
GO:0005886; GO:0009274; GO:0016491; GO:0071949
Evidence at protein level
3
null
null
null
PF02913;PF01565;
IPR004113;IPR016166;IPR036318;IPR016169;IPR016164;IPR051914;IPR006094;IPR016171;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
Rv2280
false
Mycobacterium tuberculosis
481
row_198844
false
null
212,794
P9WKC0
MKRLSSVDAAFWSAETAGWHMHVGALAICDPSDAPEYSFQRLRELIIERLPEIPQLRWRVTGAPLGLDRPWFVEDEELDIDFHIRRIGVPAPGGRRELEELVGRLMSYKLDRSRPLWELWVIEGVEGGRIATLTKMHHAIVDGVSGAGLGEILLDITPEPRPPQQETVGFVGFQIPGLERRAIGALINVGIMTPFRIVRLLEQTVRQQIAALGVAGKPARYFEAPKTRFNAPVSPHRRVTGTRVELARAKAVKDAFGVKLNDVVLALVAGAARQYLQKRDELPAKPLIAQIPVSTRSEETKADVGNQVSSMTASLATHIEDPAKRLAAIHESTLSAKEMAKAPSAHQIMGLTETTPPGLLQLAARAYTASGLSHNLAPINLVVSNVPGPPFPLYMAGARLDSLVPLGPPVMDVALNITCFSYQDYLDFGLVTTPEVANDIDEMADAIEPALAELERAAE
Putative diacyglycerol O-acyltransferase MT1468 (EC 2.3.1.20) (Putative triacylglycerol synthase MT1468)
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
83,331
459
50,063
Acyltransferase;Glycerol metabolism;Lipid biosynthesis;Lipid metabolism;Reference proteome;Transferase
GO:0001666; GO:0004144; GO:0005886; GO:0006071; GO:0019432; GO:0051701; GO:0071731
Inferred from homology
3
null
null
null
PF06974;PF03007;
IPR014292;IPR045034;IPR009721;IPR004255;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
MT1468
false
Mycobacterium tuberculosis
482
row_198998
false
null
207,388
P63836
MRVSAVAVAAPASGSGKTTIATGLIGALRQAGHTVAPFKVGPDFIDPGYHALAAGRPGRNLDPVLVGERLIGPLYAHGVAGADIAVIEGVLGLFDGRIGPAGGAPAAGSTAHVAALLGAPVILVVDARGQSHSVAALLHGFSTFDTATRIAGVILNRVGSARHEQVLRQACDQAGVAVLGAIPRTAELELPTRYLGLVTAVEYGRRARLAVQAMTAVVARHVDLAAVIACAGSQAAHPPWDPVIAVGNTARQPATVAIAAGRAFTFGYAEHAEMLRAAGAEVVEFDPLSETLPEGTDAVVLPGGFPEQFTAELSANDTVRRQINELAAAGAPVHAECAGLLYLVSELDGHPMCGVVAGSARFTQHLKLGYRDAVAVVDSALYSVGERVVGHEFHRTAVTFADSYQPAWVYQGQDVDDVRDGAVHSGVHASYLHTHPAATPGAVARFVAHAACNTPRA
Hydrogenobyrinate a,c-diamide synthase (EC 6.3.5.9) (Hydrogenobyrinic acid a,c-diamide synthase)
Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
233,413
457
46,958
ATP-binding;Cobalamin biosynthesis;Glutamine amidotransferase;Ligase;Magnesium;Nucleotide-binding;Reference proteome
GO:0005524; GO:0009236; GO:0042242; GO:0043802
Inferred from homology
3
null
null
null
PF01656;PF07685;
IPR004484;IPR029062;IPR002586;IPR011698;IPR027417;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype)
cobB BQ2027_MB2873C
false
Mycobacterium tuberculosis
483
row_193811
false
null
213,036
P9WNX9
MPIATINPATGETVKTFTAATDDEVDAAIARAHRRFADYRQTSFAQRARWANATADLLEAEADQAAAMMTLEMGKTLAAAKAEALKCAKGFRYYAENAEALLADEPADAAKVGASAAYGRYQPLGVILAVMPWNFPLWQAVRFAAPALMAGNVGLLKHASNVPQCALYLADVIARGGFPDGCFQTLLVSSGAVEAILRDPRVAAATLTGSEPAGQSVGAIAGNEIKPTVLELGGSDPFIVMPSADLDAAVSTAVTGRVQNNGQSCIAAKRFIVHADIYDDFVDKFVARMAALRVGDPTDPDTDVGPLATEQGRNEVAKQVEDAAAAGAVIRCGGKRLDRPGWFYPPTVITDISKDMALYTEEVFGPVASVFRAANIDEAVEIANATTFGLGSNAWTRDETEQRRFIDDIVAGQVFINGMTVSYPELPFGGVKRSGYGRELSAHGIREFCNIKTVWIA
Succinate-semialdehyde dehydrogenase [NADP(+)] 1 (SSADH 1) (SSDH 1) (EC 1.2.1.79)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
457
48,545
NADP;Oxidoreductase;Reference proteome;Tricarboxylic acid cycle
GO:0004030; GO:0004777; GO:0005886; GO:0006099; GO:0009013; GO:0036243
Evidence at protein level
3
null
null
null
PF00171;
IPR016161;IPR016163;IPR016160;IPR016162;IPR015590;IPR044148;IPR047110;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
gabD1 Rv0234c
false
Mycobacterium tuberculosis
484
row_199236
false
null
276,533
Q79FU0
MSFVNVAPQLVSTAAADAARIGSAINTANTAAAATTQVLAAAHDEVSTAIAALFGSHGQHYQAISAQVAAYQERFVLALSQASSTYAVAEAASATPLQNVLDAINAPVQSLTGRPLIGDGANGIDGTGQAGGNGGWLWGNGGNGGSGAPGQAGGAGGAAGLIGNGGAGGAGGQGLPFEAGANGGAGGAGGWLFGNGGAGGVGGAGGAGTTFGVAGGDGGTGGVGGHGGLIGVGGHGGDGGTGGTGGAVSLARAGTAGGAGGGPAGGIGGAGGVGGAGGAAGAVTTITHASFNDPHGVAVNPGGNIYVTNQGSNTVSVIDPVTNTVTGSITDGNGPSGVAVSPVTGLVFVTNFDSNTVSVIDPNTNTVTGSIPVGTGAYGVAVNPGGNIYVTNQFSNTVSVIDPATNTVTGSPIPVGLDPTGVAVNPVTGVVYVTNSLDDTVSVITGEPARSVCSAAI
PE-PGRS family protein PE_PGRS18
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
457
42,075
Cell wall;Reference proteome;Repeat;Secreted;Virulence
GO:0005576
Evidence at transcript level
3
SUBCELLULAR LOCATION: Secreted, cell wall {ECO:0000269|PubMed:27987050}. Note=Cell envelope-associated protein. {ECO:0000269|PubMed:27987050}.
null
null
PF01436;PF00934;PF21526;
IPR051200;IPR011045;IPR001258;IPR000084;IPR048996;IPR015943;IPR011964;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
PE_PGRS18 Rv0980c
false
Mycobacterium tuberculosis
485
row_260929
false
null
431,272
P9WGX2
MTPRSRGPRRRPLDPARRAAFETLRAVSARDAYANLVLPALLAQRGIGGRDAAFATELTYGTCRARGLLDAVIGAAAERSPQAIDPVLLDLLRLGTYQLLRTRVDAHAAVSTTVEQAGIEFDSARAGFVNGVLRTIAGRDERSWVGELAPDAQNDPIGHAAFVHAHPRWIAQAFADALGAAVGELEAVLASDDERPAVHLAARPGVLTAGELARAVRGTVGRYSPFAVYLPRGDPGRLAPVRDGQALVQDEGSQLVARALTLAPVDGDTGRWLDLCAGPGGKTALLAGLGLQCAARVTAVEPSPHRADLVAQNTRGLPVELLRVDGRHTDLDPGFDRVLVDAPCTGLGALRRRPEARWRRQPADVAALAKLQRELLSAAIALTRPGGVVLYATCSPHLAETVGAVADALRRHPVHALDTRPLFEPVIAGLGEGPHVQLWPHRHGTDAMFAAALRRLT
Putative methyltransferase MT1451 (EC 2.1.1.-)
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
83,331
457
48,493
Methyltransferase;Reference proteome;RNA-binding;S-adenosyl-L-methionine;Transferase
GO:0001510; GO:0003723; GO:0006355; GO:0008173
Inferred from homology
2
null
null
null
PF01189;PF01029;
IPR049560;IPR001678;IPR035926;IPR006027;IPR023267;IPR048019;IPR018314;IPR029063;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
MT1451
false
Mycobacterium tuberculosis
486
row_413031
false
null
26,841
P9WIQ3
MRPYYIAIVGSGPSAFFAAASLLKAADTTEDLDMAVDMLEMLPTPWGLVRSGVAPDHPKIKSISKQFEKTAEDPRFRFFGNVVVGEHVQPGELSERYDAVIYAVGAQSDRMLNIPGEDLPGSIAAVDFVGWYNAHPHFEQVSPDLSGARAVVIGNGNVALDVARILLTDPDVLARTDIADHALESLRPRGIQEVVIVGRRGPLQAAFTTLELRELADLDGVDVVIDPAELDGITDEDAAAVGKVCKQNIKVLRGYADREPRPGHRRMVFRFLTSPIEIKGKRKVERIVLGRNELVSDGSGRVAAKDTGEREELPAQLVVRSVGYRGVPTPGLPFDDQSGTIPNVGGRINGSPNEYVVGWIKRGPTGVIGTNKKDAQDTVDTLIKNLGNAKEGAECKSFPEDHADQVADWLAARQPKLVTSAHWQVIDAFERAAGEPHGRPRVKLASLAELLRIGLG
NADPH-ferredoxin reductase FprA (NFR) (EC 1.18.1.2)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
456
49,341
3D-structure;Direct protein sequencing;FAD;Flavoprotein;NADP;Oxidoreductase;Reference proteome
GO:0004324; GO:0008860; GO:0009274; GO:0016491; GO:0050660; GO:0070401
Evidence at protein level
5
null
null
null
PF07992;
IPR036188;IPR023753;IPR055275;IPR021163;
1LQT;1LQU;2C7G;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
fprA Rv3106 MTCY164.16
false
Mycobacterium tuberculosis
487
row_23486
false
null
26,916
P9WM39
MVSTHAVVAGETLSALALRFYGDAELYRLIAAASGIADPDVVNVGQRLIMPDFTRYTVVAGDTLSALALRFYGDAELNWLIAAASGIADPDVVNVGQRLIMPDFTRYTVVAGDTLSALAARFYGDASLYPLIAAVNGIADPGVIDVGQVLVIFIGRSDGFGLRIVDRNENDPRLWYYRFQTSAIGWNPGVNVLLPDDYRTSGRTYPVLYLFHGGGTDQDFRTFDFLGIRDLTAGKPIIIVMPDGGHAGWYSNPVSSFVGPRNWETFHIAQLLPWIEANFRTYAEYDGRAVAGFSMGGFGALKYAAKYYGHFASASSHSGPASLRRDFGLVVHWANLSSAVLDLGGGTVYGAPLWDQARVSADNPVERIDSYRNKRIFLVAGTSPDPANWFDSVNETQVLAGQREFRERLSNAGIPHESHEVPGGHVFRPDMFRLDLDGIVARLRPASIGAAAERAD
Esterase Rv1288 (EC 3.1.1.-)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
456
49,619
Cell wall;Hydrolase;Lipid metabolism;Reference proteome;Repeat;Secreted;Serine esterase
GO:0005576; GO:0006629; GO:0008126; GO:0016747
Evidence at protein level
5
SUBCELLULAR LOCATION: Secreted, cell wall {ECO:0000269|PubMed:30560095}. Note=Cell wall anchored. Binds peptidoglycans via the LytM domains. {ECO:0000269|PubMed:30560095}.
null
null
PF00756;PF01476;
IPR029058;IPR000801;IPR018392;IPR036779;IPR050583;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
Rv1288 MTCY373.07
false
Mycobacterium tuberculosis
488
row_23557
false
null
40,393
Q7U2S7
MTRSDTLATKLPWSDWLPRQRWYAGRNRELATVKPGVVVALRHNLDLVLVDVTYTDGATERYQVLVGWDFEPASEYGTKAAIGVADDRTGFDALYDVAGPQFLLSLIVSSAVCGTSTGEVTFTREPDVELPFAAQPRVCDAEQSNTSVIFDRRAILKVFRRVSSGINPDIELNRVLTRAGNPHVARLLGAYQFGRPNRSPTDALAYALGMVTEYEANAAEGWAMATASVRDLFAEGDLYAHEVGGDFAGESYRLGEAVASVHATLADSLGTAQATFPVDRMLARLSSTVAVVPELREYAPTIEQQFQKLAAEAITVQRVHGDLHLGQVLRTPESWLLIDFEGEPGQPLDERRAPDSPLRDVAGVLRSFEYAAYGPLVDQATDKQLAARAREWVERNRAAFCDGYAVASGIDPRDSALLLGAYELDKAVYETGYETRHRPGWLPIPLRSIARLTAS
Maltokinase (MaK) (EC 2.7.1.175) (Maltose-1-phosphate synthase)
Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
233,413
455
49,889
ATP-binding;Carbohydrate metabolism;Glycogen biosynthesis;Glycogen metabolism;Kinase;Nucleotide-binding;Reference proteome;Transferase
GO:0005524; GO:0005978; GO:0005992; GO:0016301; GO:0046835
Evidence at protein level
5
null
null
null
PF18085;
IPR011009;IPR040999;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype)
mak BQ2027_MB0132
false
Mycobacterium tuberculosis
489
row_34902
false
null
181,646
I6YC58
MTTSRTLRLLVVSALATLSGLGTPVAHAVSPPPIDERWLPESALPAPPRPTVQREVCTEVTAESGRAFGRAERSAQLADLDQVWRLTRGAGQRVAVIDTGVARHRRLPKVVAGGDYVFTGDGTADCDAHGTLVAGIIAAAPDAQSDNFSGVAPDVTLISIRQSSSKFAPVGDPSSTGVGDVDTMAKAVRTAADLGASVINISSIACVPAAAAPDDRALGAALAYAVDVKNAVIVAAAGNTGGAAQCPPQAPGVTRDSVTVAVSPAWYDDYVLTVGSVNAQGEPSAFTLAGPWVDVAATGEAVTSLSPFGDGTVNRLGGQHGSIPISGTSYAAPVVSGLAALIRARFPTLTARQVMQRIESTAHHPPAGWDPLVGNGTVDALAAVSSDSIPQAGTATSDPAPVAVPVPRRSTPGPSDRRALHTAFAGAAICLLALMATLATASRRLRPGRNGIAGD
Mycosin-4 (EC 3.4.21.-) (MycP4 protease)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
455
46,016
Cell membrane;Hydrolase;Membrane;Protease;Reference proteome;Serine protease;Signal;Transmembrane;Transmembrane helix
GO:0004252; GO:0005886; GO:0016485
Evidence at transcript level
3
SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000255}.
SIGNAL 1..25; /evidence="ECO:0000255"
TRANSMEM 432..452; /note="Helical"; /evidence="ECO:0000255"
PF00082;
IPR000209;IPR036852;IPR023827;IPR022398;IPR023828;IPR015500;IPR023834;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
mycP4 Rv3449
false
Mycobacterium tuberculosis
490
row_168692
false
null
431,113
P9WFP2
MNLTDTVATILAILALTAGTGVFVAAEFSLTALDRSTVEANARGGTSRDRFIQRAHHRLSFQLSGAQLGISITTLATGYLTEPLVAELPHPGLVAVGMSDRVADGLITFFALVIVTSLSMVFGELVPKYLAVARPLRTARSVVAGQVLFSLLLTPAIRLTNGAANWIVRRLGIEPAEELRSARTPQELVSLVRSSARSGALDDATAWLMRRSLQFGALTAEELMTPRSKIVALQTDDTIADLVAAAAASGFSRFPVVEGDLDATVGIVHVKQVFEVPPGDRAHTLLTTVAEPVAVVPSTLDGDAVMAQVRASALQTAMVVDEYGGTAGMVTLEDLIEEIVGDVRDEHDDATPDVVAAGNGWRVSGLLRIDEVASATGYRAPDGPYETISGLVLRELGHIPVAGETVELTALDQDGLPDDSMRWLATVIQMDGRRIDLLELIKMGGHADPGSGRGR
UPF0053 protein MT1890
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
83,331
455
48,154
CBS domain;Cell membrane;Membrane;Reference proteome;Repeat;Transmembrane;Transmembrane helix
GO:0005886; GO:0050660
Inferred from homology
2
SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
null
TRANSMEM 6..26; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 68..88; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 106..126; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 148..168; /note="Helical"; /evidence="ECO:0000255"
PF00571;PF01595;PF03471;
IPR000644;IPR046342;IPR002550;IPR036318;IPR016169;IPR044751;IPR005170;IPR051676;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
MT1890
false
Mycobacterium tuberculosis
491
row_412872
false
null
544,664
P64772
MNRVSASADDRAAGARPARDLVRVAFGPGVVALGIIAAVTLLQLLIANSDMTGAWGAIASMWLGVHLVPISIGGRALGVMPLLPVLLMVWATARSTARATSPQSSGLVVRWVVASALGGPLLMAAIALAVIHDASSVVTELQTPSALRAFTSVLVVHSVGAATGVWSRVGRRALAATALPDWLHDSMRAAAAGVLALLGLSGVVTAGSLVVHWATMQELYGITDSIFGQFSLTVLSVLYAPNVIVGTSAIAVGSSAHIGFATFSSFAVLGGDIPALPILAAAPTPPLGPAWVALLIVGASSGVAVGQQCARRALPFVAAMAKLLVAAVAGALVMAVLGYGGGGRLGNFGDVGVDEGALVLGVLFWFTFVGWVTVVIAGGISRRPKRLRPAPPVELDADESSPPVDMFDGAASEQPPASVAEDVPPSHDDIANGLKAPTADDEALPLSDEPPPRAD
Uncharacterized protein Mb0980
Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
233,413
455
46,089
Cell membrane;Membrane;Reference proteome;Transmembrane;Transmembrane helix
GO:0005886
Predicted
1
SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
null
TRANSMEM 26..46; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 53..73; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 77..97; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 111..131; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 146..166; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 191..211; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 232..252; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 256..276; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 278..298; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 323..343; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 357..377; /note="Helical"; /evidence="ECO:0000255"
PF19877;
IPR045931;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype)
BQ2027_MB0980
false
Mycobacterium tuberculosis
492
row_524907
false
null
4,126
I6Y778
MAPKRSSDLFSQVVNSGPGSFLARQLGVPQPETLRRYRAGEPPLTGSLLIGGAGRVVEPLRAALEKDYDLVGNNLGGRWADSFGGLVFDATGITEPAGLKGLHEFFTPVLRNLGRCGRVVVVGGTPEAAASTNERIAQRALEGFTRSLGKELRRGATTALVYLSPDAKPAATGLESTMRFLLSAKSAYVDGQVFSVGADDSTPPADWEKPLDGKVAIVTGAARGIGATIAEVFARDGAHVVAIDVESAAENLAETASKVGGTALWLDVTADDAVDKISEHLRDHHGGKADILVNNAGITRDKLLANMDDARWDAVLAVNLLAPLRLTEGLVGNGSIGEGGRVIGLSSIAGIAGNRGQTNYATTKAGMIGITQALAPGLAAKGITINAVAPGFIETQMTAAIPLATREVGRRLNSLLQGGQPVDVAEAIAYFASPASNAVTGNVIRVCGQAMIGA
3-oxoacyl-[acyl-carrier-protein] reductase [NADH] (EC 1.1.1.212) (Beta-ketoacyl CoA reductase) (FASII-like 3-oxoacyl-thioester reductase) (HMwFabG)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
454
46,830
3D-structure;Fatty acid metabolism;Lipid metabolism;NAD;Oxidoreductase;Reference proteome
GO:0006631; GO:0016616; GO:0047025
Evidence at protein level
5
null
null
null
PF13561;
IPR036291;IPR020904;IPR002347;
3M1L;3Q6I;3V1T;3V1U;4FW8;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
fabG4 Rv0242c
false
Mycobacterium tuberculosis
493
row_3275
false
null
26,890
P9WKC7
MDLMMPNDSMFLFIESREHPMHVGGLSLFEPPQGAGPEFVREFTERLVANDEFQPMFRKHPATIGGGIARVAWAYDDDIDIDYHVRRSALPSPGRVRDLLELTSRLHTSLLDRHRPLWELHVVEGLNDGRFAMYTKMHHALIDGVSAMKLAQRTLSADPDDAEVRAIWNLPPRPRTRPPSDGSSLLDALFKMAGSVVGLAPSTLKLARAALLEQQLTLPFAAPHSMFNVKVGGARRCAAQSWSLDRIKSVKQAAGVTVNDAVLAMCAGALRYYLIERNALPDRPLIAMVPVSLRSKEDADAGGNLVGSVLCNLATHVDDPAQRIQTISASMDGNKKVLSELPQLQVLALSALNMAPLTLAGVPGFLSAVPPPFNIVISNVPGPVDPLYYGTARLDGSYPLSNIPDGQALNITLVNNAGNLDFGLVGCRRSVPHLQRLLAHLESSLKDLEQAVGI
Probable diacyglycerol O-acyltransferase tgs2 (TGS2) (Diacylglycerol O-acyltransferase) (DGAT) (EC 2.3.1.20) (Long-chain-alcohol O-fatty-acyltransferase) (EC 2.3.1.75) (Probable triacylglycerol synthase tgs2) (Wax ester synthase/acyl-CoA:diacylglycerol acyltransferase) (Wax synthase) (WS)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
454
49,304
Acyltransferase;Glycerol metabolism;Lipid biosynthesis;Lipid metabolism;Reference proteome;Transferase
GO:0001666; GO:0004144; GO:0005886; GO:0006071; GO:0008374; GO:0019432; GO:0045017; GO:0047196; GO:0051701; GO:0071731
Evidence at protein level
5
null
null
null
PF06974;PF03007;
IPR014292;IPR045034;IPR009721;IPR004255;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
tgs2 Rv3734c MTV025.082c
false
Mycobacterium tuberculosis
494
row_23531
false
null
409,947
P0A5E0
MRSDTREEISAALDAYHASLSRVLDLKCDALTTPELLACLQRLEVERRRQGAAEHALINQLAGQACEEELGGTLRTALANRLHITPGEASRRIAEAEDLGERRALTGEPLPAQLTATAAAQREGKIGREHIKEIQAFFKELSAAVDLGIREAAEAQLAELATSRRPDHLHGLATQLMDWLHPDGNFSDQERARKRGITMGKQEFDGMSRISGLLTPELRATIEAVLAKLAAPGACNPDDQTPLVDDTPDADAVRRDTRSQAQRNHDAFLAALRGLLASGELGQHKGLPVTIVVSTTLKELEAATGKGVTGGGSRVPMSDLIRMASHANHYLALFDGAKPLALYHTKRLASPAQRIMLYAKDRGCSRPGCDAPAYHSEVHHVTPWTTTHRTDINDLTLACGPDNRLVEKGWKTRKNAHGDTEWLPPPHLDHGQPRINRYHHPAKILCEQDDDEPH
Uncharacterized protein Mb1179c
Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
233,413
454
49,718
Reference proteome
GO:0003676; GO:0004519; GO:0008270
Inferred from homology
2
null
null
null
PF02720;PF01844;
IPR003870;IPR002711;IPR003615;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype)
BQ2027_MB1179
false
Mycobacterium tuberculosis
495
row_392403
false
null
425,371
P63534
MRLTRAVTNPPWTVDVVVVGAGFAGLAAARELTRQGHEVLVFEGRDRVGGRSLTGRVAGVPADMGGSFIGPTQDAVLALATELGIPTTPTHRDGRNVIQWRGSARSYRGTIPKLSLTGLIDIGRLRWQFERIARGVPVAAPWDARRARELDDVSLGEWLRLVRATSSSRNLMAIMTRVTWGCEPDDVSMLHAARYVRAAGGLDRLLDVKNGAQQDRVPGGTQQIAQAAAAQLGARVLLNAAVRRIDRHGAGVTVTSDQGQAEAGFVIVAIPPAHRVAIEFDPPLPPEYQQLAHHWPQGRLSKAYAAYSTPFWRASGYSGQALSDEAPVFITFDVSPHADGPGILMGFVDARGFDSLPIEERRRDALRCFASLFGDEALDPLDYVDYRWGTEEFAPGGPTAAVPPGSWTKYGHWLREPVGPIHWASTETADEWTGYFDGAVRSGQRAAAEVAALL
Putative flavin-containing monoamine oxidase AofH (EC 1.4.3.-)
Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
233,413
454
49,136
FAD;Flavoprotein;Oxidoreductase;Reference proteome
GO:0016491
Inferred from homology
2
null
null
null
PF01593;
IPR002937;IPR036188;IPR001613;IPR050703;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype)
aofH BQ2027_MB3195
false
Mycobacterium tuberculosis
496
row_407472
false
null
544,702
P64886
MYSSSREEAVAAFDNLDTALNRVLKVSPDDLTIPECLAMLQRCEKIRRRLPAAEHPFINKLADQTDQTELGGKLPFALAERLHISRGEASRRIHEAADLGPRRTLTGQPLPPLLTATAAAQRAGHLGPAHVQVIRCFLHQLPHHVDLPTREKAEAELATLGGRFRPDQLHKLATKLADCLNPDGNYNDTDRARRRSIILGNQGPDGMSAISGYLTPEARATVDAVLAKLAAPGMANPADDTPCLAGTPSQAAIEADTRSAGQRHHDGLLAALRALLCSGELGQHNGLPAAIIVSTSLTELQSRAGHALTGGGTLLPMSDVIRLASHANHYLRIFDHGRELALYHTKRLASPGQRIVLYAKDRGCSFPNCDVPGYLTEVHHVTDFAQCQETDINELTQGCGPHHQLATTGGWITRKRKDGTTEWLPPAHLDHGQPRTNSYFHPEKLLHDSDEDDP
Uncharacterized protein Rv1792c/MT1741/Mb1728c
Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
233,413
454
49,396
Reference proteome
null
Inferred from homology
1
null
null
null
PF02720;
IPR003870;IPR003615;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype)
BQ2027_MB1728C
false
Mycobacterium tuberculosis
497
row_524945
false
null
26,984
P9WNU7
MQRRIMGIETEFGVTCTFHGHRRLSPDEVARYLFRRVVSWGRSSNVFLRNGARLYLDVGSHPEYATAECDSLVQLVTHDRAGEWVLEDLLVDAEQRLADEGIGGDIYLFKNNTDSAGNSYGCHENYLIVRAGEFSRISDVLLPFLVTRQLICGAGKVLQTPKAATYCLSQRAEHIWEGVSSATTRSRPIINTRDEPHADAEKYRRLHVIVGDSNMSETTTMLKVGTAALVLEMIESGVAFRDFSLDNPIRAIREVSHDVTGRRPVRLAGGRQASALDIQREYYTRAVEHLQTREPNAQIEQVVDLWGRQLDAVESQDFAKVDTEIDWVIKRKLFQRYQDRYDMELSHPKIAQLDLAYHDIKRGRGIFDLLQRKGLAARVTTDEEIAEAVDQPPQTTRARLRGEFISAAQEAGRDFTVDWVHLKLNDQAQRTVLCKDPFRAVDERVKRLIASM
Pup--protein ligase (EC 6.3.1.19) (Proteasome accessory factor A) (Pup-conjugating enzyme)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
452
51,384
ATP-binding;Ligase;Magnesium;Metal-binding;Nucleotide-binding;Reference proteome;Ubl conjugation pathway;Virulence
GO:0000287; GO:0005524; GO:0005886; GO:0009274; GO:0010498; GO:0016881; GO:0019787; GO:0019941; GO:0051409; GO:0052164; GO:0070490
Evidence at protein level
5
null
null
null
PF03136;
IPR022279;IPR004347;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
pafA paf Rv2097c MTCY49.37c
false
Mycobacterium tuberculosis
498
row_23623
false
null
212,871
P9WMP1
MTPRSYCVVGGGISGLTSAYRLRQAVGDDATITLFEPADRLGGVLRTEHIGGQPMDLGAEAFVLRRPEMPALLAELGLSDRQLASTGARPLIYSQQRLHPLPPQTVVGIPSSAGSMAGLVDDATLARIDAEAARPFTWQVGSDPAVADLVADRFGDQVVARSVDPLLSGVYAGSAATIGLRAAAPSVAAALDRGATSVTDAVRQALPPGSGGPVFGALDGGYQVLLDGLVRRSRVHWVRARVVQLERGWVLRDETGGRWQADAVILAVPAPRLARLVDGIAPRTHAAARQIVSASSAVVALAVPGGTAFPHCSGVLVAGDESPHAKAITLSSRKWGQRGDVALLRLSFGRFGDEPALTASDDQLLAWAADDLVTVFGVAVDPVDVRVRRWIEAMPQYGPGHADVVAELRAGLPPTLAVAGSYLDGIGVPACVGAAGRAVTSVIEALDAQVAR
Coproporphyrinogen III oxidase (EC 1.3.3.15)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
452
46,846
Cytoplasm;FAD;Flavoprotein;Heme biosynthesis;Oxidoreductase;Reference proteome
GO:0004729; GO:0005737; GO:0006783; GO:0016491
Evidence at protein level
3
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:P32397}.
null
null
PF01593;
IPR002937;IPR036188;IPR004572;IPR050464;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
cgoX hemY Rv2677c MTV010.01c
false
Mycobacterium tuberculosis
499
row_199075
false
null
432,267
P9WQN0
MPEAVSDGLFDVPGVPMTSGHDLGASAGAPLAVRMRPASLDEVVGQDHLLAPGSPLRRLVEGSGVASVILYGPPGSGKTTLAALISQATGRRFEALSALSAGVKEVRAVIENSRKALLHGEQTVLFIDEVHRFSKTQQDALLSAVEHRVVLLVAATTENPSFSVVAPLLSRSLILQLRPLTAEDTRAVVQRAIDDPRGLGRAVAVAPEAVDLLVQLAAGDARRALTALEVAAEAAQAAGELVSVQTIERSVDKAAVRYDRDGDQHYDVVSAFIKSVRGSDVDAALHYLARMLVAGEDPRFIARRLMILASEDIGMAGPSALQVAVAAAQTVALIGMPEAQLTLAHATIHLATAPKSNAVTTALAAAMNDIKAGKAGLVPAHLRDGHYSGAAALGNAQGYKYSHDDPDGVVAQQYPPDELVDVDYYRPTGRGGEREIAGRLDRLRAIIRKKRG
Uncharacterized AAA domain-containing protein MT2636
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
83,331
452
47,499
ATP-binding;Nucleotide-binding;Reference proteome
GO:0000731; GO:0003677; GO:0005524; GO:0006261; GO:0008047; GO:0016887; GO:0017116
Inferred from homology
2
null
null
null
PF00004;PF16193;PF12002;
IPR003593;IPR032423;IPR051314;IPR003959;IPR008921;IPR021886;IPR027417;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
MT2636
false
Mycobacterium tuberculosis
500
row_414012
false
null
27,031
P9WPP9
MSAVALPRVSGGHDEHGHLEEFRTDPIGLMQRVRDECGDVGTFQLAGKQVVLLSGSHANEFFFRAGDDDLDQAKAYPFMTPIFGEGVVFDASPERRKEMLHNAALRGEQMKGHAATIEDQVRRMIADWGEAGEIDLLDFFAELTIYTSSACLIGKKFRDQLDGRFAKLYHELERGTDPLAYVDPYLPIESFRRRDEARNGLVALVADIMNGRIANPPTDKSDRDMLDVLIAVKAETGTPRFSADEITGMFISMMFAGHHTSSGTASWTLIELMRHRDAYAAVIDELDELYGDGRSVSFHALRQIPQLENVLKETLRLHPPLIILMRVAKGEFEVQGHRIHEGDLVAASPAISNRIPEDFPDPHDFVPARYEQPRQEDLLNRWTWIPFGAGRHRCVGAAFAIMQIKAIFSVLLREYEFEMAQPPESYRNDHSKMVVQLAQPACVRYRRRTGV
Sterol 14alpha-demethylase (EC 1.14.15.36) (CYPLI) (Cytochrome P450 51) (Cytochrome P450-14DM) (Cytochrome P450-LIA1) (Sterol 14-alpha demethylase)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
451
50,878
3D-structure;Cytoplasm;Heme;Iron;Lipid biosynthesis;Lipid metabolism;Metal-binding;Monooxygenase;Oxidoreductase;Reference proteome;Steroid biosynthesis;Steroid metabolism;Sterol biosynthesis;Sterol metabolism
GO:0005506; GO:0005829; GO:0008398; GO:0016125; GO:0016126; GO:0016491; GO:0020037
Evidence at protein level
5
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
null
null
PF00067;
IPR050529;IPR001128;IPR017972;IPR002403;IPR036396;
1E9X;1EA1;1H5Z;1U13;1X8V;2BZ9;2CI0;2CIB;2VKU;2W09;2W0A;2W0B;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
cyp51 Rv0764c MTCY369.09c
false
Mycobacterium tuberculosis
501
row_23670
false
null
81,822
P9WKV3
MVIRVLFRPVSLIPVNNSSTPQSQGPISRRLALTALGFGVLAPNVLVACAGKVTKLAEKRPPPAPRLTFRPADSAADVVPIAPISVEVGDGWFQRVALTNSAGKVVAGAYSRDRTIYTITEPLGYDTTYTWSGSAVGHDGKAVPVAGKFTTVAPVKTINAGFQLADGQTVGIAAPVIIQFDSPISDKAAVERALTVTTDPPVEGGWAWLPDEAQGARVHWRPREYYPAGTTVDVDAKLYGLPFGDGAYGAQDMSLHFQIGRRQVVKAEVSSHRIQVVTDAGVIMDFPCSYGEADLARNVTRNGIHVVTEKYSDFYMSNPAAGYSHIHERWAVRISNNGEFIHANPMSAGAQGNSNVTNGCINLSTENAEQYYRSAVYGDPVEVTGSSIQLSYADGDIWDWAVDWDTWVSMSALPPPAAKPAATQIPVTAPVTPSDAPTPSGTPTTTNGPGG
L,D-transpeptidase 5 (LDT 5) (EC 2.3.2.-) (Ldt(Mt5))
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
451
47,891
3D-structure;Acyltransferase;Cell shape;Cell wall biogenesis/degradation;Peptidoglycan synthesis;Reference proteome;Transferase
GO:0005576; GO:0008360; GO:0016746; GO:0018104; GO:0071555; GO:0071972
Evidence at protein level
4
null
null
null
PF17964;PF03734;
IPR041280;IPR050979;IPR005490;IPR038063;
1U8R;2ISZ;2IT0;6D5A;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
lprQ Rv0483 MTCY20G9.09
false
Mycobacterium tuberculosis
502
row_72268
false
null
547,054
P9WM57
MCSTREEITEAFASLATALSRVLGLTFDALTTPERLALLEHCETARRQLPSVEHTLINQIGEQSTEEELGGKLGLTLADRLRITRSEAKRRVAEAADLGQRRALTGEPLPPLLTATAKAQRHGLIGDGHVEVIRAFVHRLPSWVDLKTLEKAERDLAKQATQYRPDQLAKLAARIMDCLNPDGDYTDEDRARRRGLTLGKQDVDGMSRLSGYVTPELRATIEAVWAKLAAPGMCNPEQKAPCVNGAPSKEQARRDTRSCPQRNHDALNAELRSLLTSGNLGQHNGLPASIIVTTTLKDLEAAAGAGLTGGGTILPISDVIRLARHANHYLAIFDRGKALALYHTKRLASPAQRIMLYAKDSGCSAPGCDVPGYYCEVHHVTPYAQCRNTDVNDLTLGCGGHHPLAERGWTTRKNAHGDTEWLPPPHLDHGQPRVNTFHHPEKLLADDEGDP
Uncharacterized protein Rv1128c
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
451
49,275
Reference proteome
GO:0009274
Inferred from homology
1
null
null
null
PF02720;
IPR003870;IPR003615;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
Rv1128c MTCY22G8.17c
false
Mycobacterium tuberculosis
503
row_527146
false
null
26,716
P9WFX1
MSELSVATGAVSTASSSIPMPAGVNPADLAAELAAVVTESVDEDYLLYECDGQWVLAAGVQAMVELDSDELRVIRDGVTRRQQWSGRPGAALGEAVDRLLLETDQAFGWVAFEFGVHRYGLQQRLAPHTPLARVFSPRTRIMVSEKEIRLFDAGIRHREAIDRLLATGVREVPQSRSVDVSDDPSGFRRRVAVAVDEIAAGRYHKVILSRCVEVPFAIDFPLTYRLGRRHNTPVRSFLLQLGGIRALGYSPELVTAVRADGVVITEPLAGTRALGRGPAIDRLARDDLESNSKEIVEHAISVRSSLEEITDIAEPGSAAVIDFMTVRERGSVQHLGSTIRARLDPSSDRMAALEALFPAVTASGIPKAAGVEAIFRLDECPRGLYSGAVVMLSADGGLDAALTLRAAYQVGGRTWLRAGAGIIEESEPEREFEETCEKLSTLTPYLVARQ
Salicylate synthase (Chorismate mutase) (CM) (EC 5.4.99.5) (Isochorismate synthase/isochorismate lyase) (EC 4.2.99.21, EC 5.4.4.2) (Mycobactin synthase protein)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
450
48,754
3D-structure;Isomerase;Lyase;Magnesium;Metal-binding;Reference proteome
GO:0000162; GO:0000287; GO:0004106; GO:0005886; GO:0008909; GO:0009697; GO:0010106; GO:0016833; GO:0019540; GO:0043904; GO:0044847
Evidence at protein level
5
null
null
null
PF00425;
IPR005801;IPR019999;IPR015890;IPR019996;
2G5F;2I6Y;3LOG;3RV6;3RV7;3RV8;3RV9;3ST6;3VEH;6ZA4;6ZA5;6ZA6;8QC4;8QN5;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
mbtI trpE2 Rv2386c
false
Mycobacterium tuberculosis
504
row_23363
false
null
27,043
P9WPY5
MKTWPAPTAPTPVRATVTVPGSKSQTNRALVLAALAAAQGRGASTISGALRSRDTELMLDALQTLGLRVDGVGSELTVSGRIEPGPGARVDCGLAGTVLRFVPPLAALGSVPVTFDGDQQARGRPIAPLLDALRELGVAVDGTGLPFRVRGNGSLAGGTVAIDASASSQFVSGLLLSAASFTDGLTVQHTGSSLPSAPHIAMTAAMLRQAGVDIDDSTPNRWQVRPGPVAARRWDIEPDLTNAVAFLSAAVVSGGTVRITGWPRVSVQPADHILAILRQLNAVVIHADSSLEVRGPTGYDGFDVDLRAVGELTPSVAALAALASPGSVSRLSGIAHLRGHETDRLAALSTEINRLGGTCRETPDGLVITATPLRPGIWRAYADHRMAMAGAIIGLRVAGVEVDDIAATTKTLPEFPRLWAEMVGPGQGWGYPQPRSGQRARRATGQGSGG
3-phosphoshikimate 1-carboxyvinyltransferase (EC 2.5.1.19) (5-enolpyruvylshikimate-3-phosphate synthase) (EPSP synthase) (EPSPS)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
450
46,426
3D-structure;Amino-acid biosynthesis;Aromatic amino acid biosynthesis;Cytoplasm;Reference proteome;Transferase
GO:0003866; GO:0005829; GO:0005886; GO:0008652; GO:0009073; GO:0009423
Evidence at protein level
5
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00210}.
null
null
PF00275;
IPR001986;IPR036968;IPR006264;IPR023193;IPR013792;
2BJB;2O0B;2O0D;2O0E;2O0X;2O0Z;2O15;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
aroA Rv3227
false
Mycobacterium tuberculosis
505
row_23682
false
null
529,772
A5U683
MTADEPRSDDSSGSAPQPAATPVPRPGPRPGPRPVPRPTSYPVGAHPPSDPHRFGRIDDDGTVWLVSASGERIVGSWQAGDPEAAFAHFGRRFDDLSTEIMLMDERLASGTGDARKIKAHAIALAETLPTACVLGDVDALADRLTSIRDRAEVIAAADRSRREEHRAAQTARKEALAAEAEELAANATQWKVAGDRLRAILDEWKTISGVDRKVDDALWKRYSTARDTFNRRRGSHFAELDRERSGVRQSKERLCERAEELSESTDWTATSAEFRKLLADWKAAGRASKDVDDALWRRFKAAQDSFFTARNAATAEKEAELRANADAKEALLAEAERLDTTNHEAARAALRSIAEKWDAIGKVSRERAAELERRLRAVEKKVREAGEADWSDPQARARAEQFRARAEQFEHQAEKAAAAGRTKEADEAKANAEQWRQWAEAAADALTRRP
Uncharacterized protein MRA_2757
Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra)
419,947
450
49,796
Coiled coil;Reference proteome
null
Evidence at protein level
1
null
null
null
PF03993;
IPR007139;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
MRA_2757
false
Mycobacterium tuberculosis
506
row_510107
false
null
27,059
P9WQ77
MAAVVKSVALAGRPTTPDRVHEVLGRSMLVDGLDIVLDLTRSGGSYLVDAITGRRYLDMFTFVASSALGMNPPALVDDREFHAELMQAALNKPSNSDVYSVAMARFVETFARVLGDPALPHLFFVEGGALAVENALKAAFDWKSRHNQAHGIDPALGTQVLHLRGAFHGRSGYTLSLTNTKPTITARFPKFDWPRIDAPYMRPGLDEPAMAALEAEALRQARAAFETRPHDIACFVAEPIQGEGGDRHFRPEFFAAMRELCDEFDALLIFDEVQTGCGLTGTAWAYQQLDVAPDIVAFGKKTQVCGVMAGRRVDEVADNVFAVPSRLNSTWGGNLTDMVRARRILEVIEAEGLFERAVQHGKYLRARLDELAADFPAVVLDPRGRGLMCAFSLPTTADRDELIRQLWQRAVIVLPAGADTVRFRPPLTVSTAEIDAAIAAVRSALPVVT
L-lysine-epsilon aminotransferase (L-lysine aminotransferase) (LAT) (EC 2.6.1.36) (Lysine 6-aminotransferase)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
449
49,012
3D-structure;Aminotransferase;Pyridoxal phosphate;Reference proteome;Transferase
GO:0009450; GO:0017000; GO:0030170; GO:0045484
Evidence at protein level
5
null
null
null
PF00202;
IPR005814;IPR049704;IPR017657;IPR015424;IPR015421;IPR015422;
2CIN;2CJD;2CJG;2CJH;2JJE;2JJF;2JJG;2JJH;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
lat Rv3290c MTCY71.30
false
Mycobacterium tuberculosis
507
row_23697
false
null
207,246
P63505
MASLQQSRRLVTEIPGPASQALTHRRAAAVSSGVGVTLPVFVARAGGGIVEDVDGNRLIDLGSGIAVTTIGNSSPRVVDAVRTQVAEFTHTCFMVTPYEGYVAVAEQLNRITPGSGPKRSVLFNSGAEAVENAVKIARSYTGKPAVVAFDHAYHGRTNLTMALTAKSMPYKSGFGPFAPEIYRAPLSYPYRDGLLDKQLATNGELAAARAIGVIDKQVGANNLAALVIEPIQGEGGFIVPAEGFLPALLDWCRKNHVVFIADEVQTGFARTGAMFACEHEGPDGLEPDLICTAKGIADGLPLSAVTGRAEIMNAPHVGGLGGTFGGNPVACAAALATIATIESDGLIERARQIERLVTDRLTTLQAVDDRIGDVRGRGAMIAVELVKSGTTEPDAGLTERLATAAHAAGVIILTCGMFGNIIRLLPPLTIGDELLSEGLDIVCAILADL
4-aminobutyrate aminotransferase (EC 2.6.1.19) ((S)-3-amino-2-methylpropionate transaminase) (EC 2.6.1.22) (GABA aminotransferase) (GABA-AT) (Gamma-amino-N-butyrate transaminase) (GABA transaminase) (Glutamate:succinic semialdehyde transaminase) (L-AIBAT)
Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
233,413
449
46,813
Aminotransferase;Pyridoxal phosphate;Reference proteome;Transferase
GO:0009450; GO:0030170; GO:0034386; GO:0042802; GO:0047298
Inferred from homology
3
null
null
null
PF00202;
IPR004632;IPR005814;IPR049704;IPR050103;IPR015424;IPR015421;IPR015422;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype)
gabT BQ2027_MB2620
false
Mycobacterium tuberculosis
508
row_193669
false
null
212,831
P9WKW5
MLDAPEQDPVDPGDPASPPHGEAEQPLPGPRWPRALRASATRRALLLTALGGLLIAGLVTAIPAVGRAPERLAGYIASNPVPSTGAKINASFNRVASGDCLMWPDGTPESAAIVSCADEHRFEVAESIDMRTFPGMEYGQNAAPPSPARIQQISEEQCEAAVRRYLGTKFDPNSKFTISMLWPGDRAWRQAGERRMLCGLQSPGPNNQQLAFKGKVADIDQSKVWPAGTCLGIDATTNQPIDVPVDCAAPHAMEVSGTVNLAERFPDALPSEPEQDGFIKDACTRMTDAYLAPLKLRTTTLTLIYPTLTLPSWSAGSRVVACSIGATLGNGGWATLVNSAKGALLINGQPPVPPPDIPEERLNLPPIPLQLPTPRPAPPAQQLPSTPPGTQHLPAQQPVVTPTRPPESHAPASAAPAETQPPPPDAGAPPATQSPEATPPGPAEPAPAG
Uncharacterized membrane protein Rv3835
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
449
47,043
Cell membrane;Membrane;Reference proteome;Secreted;Transmembrane;Transmembrane helix
GO:0005576; GO:0005886; GO:0009274
Evidence at protein level
3
SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. Secreted {ECO:0000269|PubMed:17443846}.
null
TRANSMEM 45..65; /note="Helical"; /evidence="ECO:0000255"
PF13845;
IPR026004;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
Rv3835
false
Mycobacterium tuberculosis
509
row_199035
false
null
212,917
P9WN09
MRVSCVYATASRWGGPPVASEVRGDAAISTTPDAAPGLAARRRRILFVAEAVTLAHVVRPFALAQSLDPSRYEVHFACDPRYNQLLGPLPFRHHAIHTIPSERFFGNLTQGRFYAMRTLRKYVEADLRVLDEIAPDLVVGDLRISLSVSARLAGIPYIAIANAYWSPYAQRRFPLPDVIWTRLFGVRLVKLLYRLERPLLFALQCMPLNWVRRRHGLSSLGWNLCRIFTDGDHTLYADVPELMPTYDLPANHEYLGPVLWSPAGKPPTWWDSLPTDRPIVYATLGTSGGRNLLQLVLNALAELPVTVIAATAGRSDLKTVPANAFVADYLPGEAAAARSAVVVCNGGSLTTQQALVAGVPVIGVAGNLDQHLNMEAVERAGAGVLLRTERLKSQRVAGAVMQVISRSEYRQAAARLADAFGRDRVGFPQHVENALRLMPENRPRTWLAS
PGL/p-HBAD biosynthesis rhamnosyltransferase (EC 2.4.1.-)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
449
49,433
Glycosyltransferase;Reference proteome;Transferase
GO:0005886; GO:0008194; GO:0009247; GO:0016758
Evidence at protein level
3
null
null
null
PF06722;
IPR010610;IPR002213;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
Rv2962c
false
Mycobacterium tuberculosis
510
row_199120
false
null
432,157
P9WPN0
MASTLTTGLPPGPRLPRYLQSVLYLRFREWFLPAMHRKYGDVFSLRVPPYADNLVVYTRPEHIKEIFAADPRSLHAGEGNHILGFVMGEHSVLMTDEAEHARMRSLLMPAFTRAALRGYRDMIASVAREHITRWRPHATINSLDHMNALTLDIILRVVFGVTDPKVKAELTSRLQQIINIHPAILAGVPYPSLKRMNPWKRFFHNQTKIDEILYREIASRRIDSDLTARTDVLSRLLQTKDTPTKPLTDAELRDQLITLLLAGHETTAAALSWTLWELAHAPEIQSQVVWAAVGGDDGFLEAVLKEGMRRHTVIASTARKVTAPAEIGGWRLPAGTVVNTSILLAHASEVSHPKPTEFRPSRFLDGSVAPNTWLPFGGGVRRCLGFGFALTEGAVILQEIFRRFTITAAGPSKGETPLVRNITTVPKHGAHLRLIPQRRLGGLGDSDPP
Putative cytochrome P450 135A1 (EC 1.14.-.-)
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
83,331
449
50,011
Heme;Iron;Metal-binding;Monooxygenase;Oxidoreductase;Reference proteome
GO:0004497; GO:0005506; GO:0016705; GO:0020037
Inferred from homology
2
null
null
null
PF00067;
IPR001128;IPR017972;IPR002401;IPR036396;IPR050121;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
cyp135A1 MT0342
false
Mycobacterium tuberculosis
511
row_413902
false
null
27,009
P9WP79
MTGPEHGSASTIEILPVIGLPEFRPGDDLSAAVAAAAPWLRDGDVVVVTSKVVSKCEGRLVPAPEDPEQRDRLRRKLIEDEAVRVLARKDRTLITENRLGLVQAAAGVDGSNVGRSELALLPVDPDASAATLRAGLRERLGVTVAVVITDTMGRAWRNGQTDAAVGAAGLAVLRNYAGVRDPYGNELVVTEVAVADEIAAAADLVKGKLTATPVAVVRGFGVSDDGSTARQLLRPGANDLFWLGTAEALELGRQQAQLLRRSVRRFSTDPVPGDLVEAAVAEALTAPAPHHTRPTRFVWLQTPAIRARLLDRMKDKWRSDLTSDGLPADAIERRVARGQILYDAPEVVIPMLVPDGAHSYPDAARTDAEHTMFTVAVGAAVQALLVALAVRGLGSCWIGSTIFAADLVRDELDLPVDWEPLGAIAIGYADEPSGLRDPVPAADLLILK
Bifunctional F420 biosynthesis protein FbiB [Includes: Coenzyme F420:L-glutamate ligase (EC 6.3.2.31) (EC 6.3.2.34) (Coenzyme F420-0:L-glutamate ligase) (Coenzyme F420-1:gamma-L-glutamate ligase); Dehydro-coenzyme F420-0 reductase (EC 1.3.8.17)]
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
448
47,578
3D-structure;GTP-binding;Ligase;Magnesium;Manganese;Metal-binding;Multifunctional enzyme;Nucleotide-binding;Oxidoreductase;Potassium;Reference proteome
GO:0005525; GO:0005886; GO:0046872; GO:0052618; GO:0052619; GO:0052645; GO:0052890; GO:2001121
Evidence at protein level
5
null
null
null
PF01996;PF00881;
IPR008225;IPR002847;IPR019943;IPR023661;IPR029479;IPR000415;
4XOM;4XOO;4XOQ;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
fbiB Rv3262
false
Mycobacterium tuberculosis
512
row_23648
false
null
81,779
P9WJI9
MGPPPAARRREGEPDNQDPAGLLTDKYELTMLAAALRDGSANRPTTFEVFARRLPTGRRYGVVAGTGRLLEALPQFRFDADACELLAQFLDPATVRYLREFRFRGDIDGYAEGELYFPGSPVLSVRGSFAECVLLETLVLSIFNHDTAIASAAARMVSAAGGRPLIEMGSRRTHERAAVAAARAAYIAGFAASSNLAAQRRYGVPAHGTAAHAFTMLHAQHGGPTELAERAAFRAQVEALGPGTTLLVDTYDVTTGVANAVAAAGAELGAIRIDSGELGVLARQAREQLDRLGATRTRIVVSGDLDEFSIAALRGEPVDSYGVGTSLVTGSGAPTANMVYKLVEVDGVPVQKRSSYKESPGGRKEALRRSRATGTITEELVHPAGRPPVIVEPHRVLTLPLVRAGQPVADTSLAAARQLVASGLRSLPGDGLKLAPGEPAIPTRTIPA
Nicotinate phosphoribosyltransferase pncB1 (NAPRTase pncB1) (EC 6.3.4.21)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
448
47,227
Ligase;Phosphoprotein;Pyridine nucleotide biosynthesis;Reference proteome;Transferase
GO:0004516; GO:0005829; GO:0009274; GO:0009435; GO:0034355; GO:0047280
Evidence at protein level
4
null
null
null
PF04095;PF17767;
IPR013785;IPR041525;IPR040727;IPR007229;IPR006405;IPR036068;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
pncB1 Rv1330c MTCY130.15c
false
Mycobacterium tuberculosis
513
row_72226
false
null
81,798
P9WKA5
MSPIDALFLSAESREHPLHVGALQLFEPPAGAGRGFVRETYQAMLQCREIAPLFRKRPTSLHGALINLGWSTDADVDLGYHARRSALPAPGRVRELLELTSRLHSNLLDRHRPLWETHVIEGLRDGRFAIYSKMHHALVDGVSGLTLMRQPMTTDPIEGKLRTAWSPATQHTAIKRRRGRLQQLGGMLGSVAGLAPSTLRLARSALIEQQLTLPFGAPHTMLNVAVGGARRCAAQSWPLDRVKAVKDAAGVSLNDVVLAMCAGALREYLDDNDALPDTPLVAMVPVSLRTDRDSVGGNMVGAVLCNLATHLDDPADRLNAIHASMRGNKNVLSQLPRAQALAVSLLLLSPAALNTLPGLAKATPPPFNVCISNVPGAREPLYFNGARMVGNYPMSLVLDGQALNITLTSTADSLDFGVVGCRRSVPHVQRVLSHLETSLKELERAVGL
Putative diacyglycerol O-acyltransferase Rv3740c (EC 2.3.1.20) (Putative triacylglycerol synthase Rv3740c)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
448
48,353
Acyltransferase;Glycerol metabolism;Lipid biosynthesis;Lipid metabolism;Reference proteome;Transferase
GO:0001666; GO:0004144; GO:0005886; GO:0006071; GO:0008374; GO:0010025; GO:0019432; GO:0047196; GO:0051701; GO:0071731
Evidence at protein level
4
null
null
null
PF06974;PF03007;
IPR014292;IPR045034;IPR009721;IPR004255;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
Rv3740c MTV025.088c
false
Mycobacterium tuberculosis
514
row_72244
false
null
112,276
A1KPC8
MGRLFGTDGVRGVANRELTAELALALGAAAARRLSRSGAPGRRVAVLGRDPRASGEMLEAAVIAGLTSEGVDALRVGVLPTPAVAYLTGAYDADFGVMISASHNPMPDNGIKIFGPGGHKLDDDTEDQIEDLVLGVSRGPGLRPAGAGIGRVIDAEDATERYLRHVAKAATARLDDLAVVVDCAHGAASSAAPRAYRAAGARVIAINAEPNGRNINDGCGSTHLDPLRAAVLAHRADLGLAHDGDADRCLAVDANGDLVDGDAIMVVLALAMKEAGELACNTLVATVMSNLGLHLAMRSAGVTVRTTAVGDRYVLEELRAGDYSLGGEQSGHIVMPALGSTGDGIVTGLRLMTRMVQTGSSLSDLASAMRTLPQVLINVEVVDKATAAAAPSVRTAVEQAAAELGDTGRILLRPSGTEPMIRVMVEAADEGVAQRLAATVADAVSTAR
Phosphoglucosamine mutase (EC 5.4.2.10)
Mycobacterium bovis (strain BCG / Pasteur 1173P2)
410,289
448
45,873
Isomerase;Magnesium;Metal-binding;Phosphoprotein
GO:0000287; GO:0004615; GO:0005829; GO:0005975; GO:0006048; GO:0008966; GO:0009252
Inferred from homology
3
null
null
null
PF02878;PF02879;PF02880;PF00408;
IPR005844;IPR016055;IPR005845;IPR005846;IPR005843;IPR036900;IPR016066;IPR005841;IPR006352;IPR050060;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype), Mycobacterium tuberculosis variant bovis BCG (no rank)
glmM BCG_3507c
false
Mycobacterium tuberculosis
515
row_100741
false
null
547,094
P9WMB0
MAFDAAMSTHEDLLATIRYVRDRTGDPNAWQTGLTPTEVTAVVTSTTRSEQLDAILRKIRQRHSNLYYPAPPDREQGDAARAIADAEAALAHQNSATAQLDLQVVSAILNAHLKTVEGGESLHELQQEIEAAVRIRSDLDTPAGARDFQRFLIGKLKDIREVVATASLDAASKSALMAAWTSLYDASKGDRGDADDRGPASVGSGGAPARGAGQQPELPTRAEPDCLLDSLLLEDPGLLADDLQVPGGTSAAIPSASSTPSLPNLGGATMPGGGATPALVPGVSAPGGLPLSGLLRGVGDEPELTDFDERGQEVRDPADYEHANEPDERRADDREGADEDAGLGKSESPPQAPTTVTLPNGETVTAASPQLAAAIKAAASGTPIADAFQQQGIAIPLPGTAVANPVDSARISAGDVGVFTATPLPLALAKLFWTARFNTSQPCEGQTF
Uncharacterized protein MT0029
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
83,331
448
46,449
Reference proteome
null
Predicted
1
null
null
null
PF10774;
IPR019710;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
MT0029
false
Mycobacterium tuberculosis
516
row_527186
false
null
26,848
P9WIU7
MNELLHLAPNVWPRNTTRDEVGVVCIAGIPLTQLAQEYGTPLFVIDEDDFRSRCRETAAAFGSGANVHYAAKAFLCSEVARWISEEGLCLDVCTGGELAVALHASFPPERITLHGNNKSVSELTAAVKAGVGHIVVDSMTEIERLDAIAGEAGIVQDVLVRLTVGVEAHTHEFISTAHEDQKFGLSVASGAAMAAVRRVFATDHLRLVGLHSHIGSQIFDVDGFELAAHRVIGLLRDVVGEFGPEKTAQIATVDLGGGLGISYLPSDDPPPIAELAAKLGTIVSDESTAVGLPTPKLVVEPGRAIAGPGTITLYEVGTVKDVDVSATAHRRYVSVDGGMSDNIRTALYGAQYDVRLVSRVSDAPPVPARLVGKHCESGDIIVRDTWVPDDIRPGDLVAVAATGAYCYSLSSRYNMVGRPAVVAVHAGNARLVLRRETVDDLLSLEVR
Diaminopimelate decarboxylase (DAP decarboxylase) (DAPDC) (EC 4.1.1.20)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
447
47,458
3D-structure;Amino-acid biosynthesis;Decarboxylase;Disulfide bond;Lyase;Lysine biosynthesis;Pyridoxal phosphate;Reference proteome
GO:0008836; GO:0009089; GO:0009274; GO:0030170
Evidence at protein level
5
null
null
null
PF02784;PF00278;
IPR009006;IPR002986;IPR022643;IPR022657;IPR022644;IPR022653;IPR000183;IPR029066;
1HKV;1HKW;2O0T;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
lysA Rv1293 MTCY373.13
false
Mycobacterium tuberculosis
517
row_23491
false
null
4,611
O05461
MHRIFLITVALALLTASPASAITPPPIDPGALPPDVTGPDQPTEQRVLCASPTTLPGSGFHDPPWSNTYLGVADAHKFATGAGVTVAVIDTGVDASPRVPAEPGGDFVDQAGNGLSDCDAHGTLTASIIAGRPAPTDGFVGVAPDARLLSLRQTSEAFEPVGSQANPNDPNATPAAGSIRSLARAVVHAANLGVGVINISEAACYKVSRPIDETSLGASIDYAVNVKGVVVVVAAGNTGGDCVQNPAPDPSTPGDPRGWNNVQTVVTPAWYAPLVLSVGGIGQTGMPSSFSMHGPWVDVAAPAENIVALGDTGEPVNALQGREGPVPIAGTSFAAAYVSGLAALLRQRFPDLTPAQIIHRITATARHPGGGVDDLVGAGVIDAVAALTWDIPPGPASAPYNVRRLPPPVVEPGPDRRPITAVALVAVGLTLALGLGALARRALSRR
Mycosin-1 (EC 3.4.21.-) (MycP1 protease)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
446
45,118
Cell membrane;Hydrolase;Membrane;Protease;Reference proteome;Serine protease;Signal;Transmembrane;Transmembrane helix
GO:0004252; GO:0005886; GO:0006508; GO:0009986; GO:0016485; GO:0044003; GO:0051046
Evidence at protein level
5
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:10974545, ECO:0000269|PubMed:12366866}; Single-pass membrane protein {ECO:0000255}. Note=Cell wall-associated. {ECO:0000269|PubMed:10974545, ECO:0000269|PubMed:12366866}.
SIGNAL 1..21; /evidence="ECO:0000255"
TRANSMEM 419..439; /note="Helical"; /evidence="ECO:0000255"
PF00082;
IPR000209;IPR036852;IPR015500;IPR023834;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
mycP1 Rv3883c
false
Mycobacterium tuberculosis
518
row_3691
false
null
81,688
P9WGK7
MNILSRIFARTPSLRTRVVVATAIGAAIPVLIVGTVVWVGITNDRKERLDRRLDEAAGFAIPFVPRGLDEIPRSPNDQDALITVRRGNVIKSNSDITLPKLQDDYADTYVRGVRYRVRTVEIPGPEPTSVAVGATYDATVAETNNLHRRVLLICTFAIGAAAVFAWLLAAFAVRPFKQLAEQTRSIDAGDEAPRVEVHGASEAIEIAEAMRGMLQRIWNEQNRTKEALASARDFAAVSSHELRTPLTAMRTNLEVLSTLDLPDDQRKEVLNDVIRTQSRIEATLSALERLAQGELSTSDDHVPVDITDLLDRAAHDAARIYPDLDVSLVPSPTCIIVGLPAGLRLAVDNAIANAVKHGGATLVQLSAVSSRAGVEIAIDDNGSGVPEGERQVVFERFSRGSTASHSGSGLGLALVAQQAQLHGGTASLENSPLGGARLVLRLPGPS
Sensor-type histidine kinase PrrB (EC 2.7.13.3)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
446
47,829
3D-structure;ATP-binding;Cell membrane;Kinase;Membrane;Nucleotide-binding;Phosphoprotein;Reference proteome;Transferase;Transmembrane;Transmembrane helix;Two-component regulatory system
GO:0000155; GO:0000160; GO:0005524; GO:0005886; GO:0009274; GO:0042802
Evidence at protein level
4
SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
null
TRANSMEM 19..39; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 151..171; /note="Helical"; /evidence="ECO:0000255"
PF00672;PF02518;PF00512;
IPR003660;IPR036890;IPR005467;IPR003661;IPR036097;IPR004358;IPR050428;
1YS3;1YSR;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
prrB Rv0902c MTCY31.30c
false
Mycobacterium tuberculosis
519
row_72137
false
null
81,800
P9WKA9
MAQLTALDAGFLKSRDPERHPGLAIGAVAVVNGAAPSYDQLKTVLTERIKSIPRCTQVLATEWIDYPGFDLTQHVRRVALPRPGDEAELFRAIALALERPLDPDRPLWECWIIEGLNGNRWAILIKIHHCMAGAMSAAHLLARLCDDADGSAFANNVDIKQIPPYGDARSWAETLWRMSVSIAGAVCTAAARAVSWPAVTSPAGPVTTRRRYQAVRVPRDAVDAVCHKFGVTANDVALAAITEGFRTVLLHRGQQPRADSLRTLEKTDGSSAMLPYLPVEYDDPVRRLRTVHNRSQQSGRRQPDSLSDYTPLMLCAKMIHALARLPQQGIVTLATSAPRPRHQLRLMGQKMDQVLPIPPTALQLSTGIAVLSYGDELVFGITADYDAASEMQQLVNGIELGVARLVALSDDSVLLFTKDRRKRSSRALPSAARRGRPSVPTARARH
Putative diacyglycerol O-acyltransferase Rv3371 (EC 2.3.1.20) (Putative triacylglycerol synthase Rv3371)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
446
48,847
Acyltransferase;Glycerol metabolism;Lipid biosynthesis;Lipid metabolism;Reference proteome;Transferase
GO:0001666; GO:0004144; GO:0005886; GO:0006071; GO:0008374; GO:0009274; GO:0019432; GO:0051701; GO:0071731
Evidence at protein level
4
null
null
null
PF06974;PF03007;
IPR014292;IPR023213;IPR045034;IPR009721;IPR004255;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
Rv3371 MTV004.29
false
Mycobacterium tuberculosis
520
row_72246
false
null
81,857
P9WN37
MDRQKEFVLRTLEERDIRFVRLWFTDVLGFLKSVAIAPAELEGAFEEGIGFDGSSIEGFARVSESDTVAHPDPSTFQVLPWATSSGHHHSARMFCDITMPDGSPSWADPRHVLRRQLTKAGELGFSCYVHPEIEFFLLKPGPEDGSVPVPVDNAGYFDQAVHDSALNFRRHAIDALEFMGISVEFSHHEGAPGQQEIDLRFADALSMADNVMTFRYVIKEVALEEGARASFMPKPFGQHPGSAMHTHMSLFEGDVNAFHSADDPLQLSEVGKSFIAGILEHACEISAVTNQWVNSYKRLVQGGEAPTAASWGAANRSALVRVPMYTPHKTSSRRVEVRSPDSACNPYLTFAVLLAAGLRGVEKGYVLGPQAEDNVWDLTPEERRAMGYRELPSSLDSALRAMEASELVAEALGEHVFDFFLRNKRTEWANYRSHVTPYELRTYLSL
Glutamine synthetase (GS) (EC 6.3.1.2) (Glutamate--ammonia ligase) (Glutamine synthetase I alpha) (GSI alpha)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
446
49,608
ATP-binding;Cytoplasm;Isopeptide bond;Ligase;Magnesium;Metal-binding;Nucleotide-binding;Reference proteome;Ubl conjugation
GO:0004356; GO:0005524; GO:0005737; GO:0005886; GO:0006542; GO:0046872; GO:0050001
Evidence at protein level
4
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:P12425}.
null
null
PF00120;PF03951;
IPR008147;IPR036651;IPR014746;IPR008146;IPR027303;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
glnA2 Rv2222c MTCY190.33c MTCY427.03c
false
Mycobacterium tuberculosis
521
row_72301
false
null
112,164
A1KI95
MSTFIGQLFGFAVIVYLVWRFIVPLVGRLMSARQDTVRQQLADAAAAADRLAEASQAHTKALEDAKSEAHRVVEEARTDAERIAEQLEAQADVEAERIKMQGARQVDLIRAQLTRQLRLELGHESVRQARELVRNHVADQAQQSATVDRFLDQLDAMAPATADVDYPLLAKMRSASRRALTSLVDWFGTMAQDLDHQGLTTLAGELVSVARLLDREAVVTRYLTVPAEDATPRIRLIERLVSGKVGAPTLEVLRTAVSKRWSANSDLIDAIEHVSRQALLELAERAGQVDEVEDQLFRFSRILDVQPRLAILLGDCAVPAEGRVRLLRKVLERADSTVNPVVVALLSHTVELLRGQAVEEAVLFLAEVAVARRGEIVAQVGAAAELSDAQRTRLTEVLSRIYGHPVTVQLHIDAALLGGLSIAVGDEVIDGTLSSRLAAAEARLPD
ATP synthase subunit b-delta [Includes: ATP synthase subunit b (ATP synthase F(0) sector subunit b 2) (ATPase subunit I 2) (F-type ATPase subunit b 2) (F-ATPase subunit b 2); ATP synthase subunit delta (ATP synthase F(1) sector subunit delta) (F-type ATPase subunit delta) (F-ATPase subunit delta)]
Mycobacterium bovis (strain BCG / Pasteur 1173P2)
410,289
446
48,806
ATP synthesis;Cell membrane;CF(0);Hydrogen ion transport;Ion transport;Membrane;Multifunctional enzyme;Transmembrane;Transmembrane helix;Transport
GO:0005886; GO:0045259; GO:0046933
Inferred from homology
3
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}.
null
TRANSMEM 4..24; /note="Helical"; /evidence="ECO:0000255"
PF00430;PF00213;
IPR028987;IPR002146;IPR005864;IPR026015;IPR000711;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype), Mycobacterium tuberculosis variant bovis BCG (no rank)
atpFH atpF atpH BCG_1367
false
Mycobacterium tuberculosis
522
row_100629
false
null
431,751
P9WK88
MVEPGNLAGATGAEWIGRPPHEELQRKVRPLLPSDDPFYFPPAGYQHAVPGTVLRSRDVELAFMGLIPQPVTATQLLYRTTNMYGNPEATVTTVIVPAELAPGQTCPLLSYQCAIDAMSSRCFPSYALRRRAKALGSLTQMELLMISAALAEGWAVSVPDHEGPKGLWGSPYEPGYRVLDGIRAALNSERVGLSPATPIGLWGYSGGGLASAWAAEACGEYAPDLDIVGAVLGSPVGDLGHTFRRLNGTLLAGLPALVVAALQHSYPGLARVIKEHANDEGRQLLEQLTEMTTVDAVIRMAGRDMGDFLDEPLEDILSTPEVSHVFGDTKLGSAVPTPPVLIVQAVHDYLIDVSDIDALADSYTAGGANVTYHRDLFSEHVSLHPLSAPMTLRWLTDRFAGKPLTDHRVRTTWPTIFNPMTYAGMARLAVIAAKVITGRKLSRRPL
Probable inactive lipase MT1628
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
83,331
446
48,029
Reference proteome
GO:0004806; GO:0016042
Inferred from homology
2
null
null
null
PF03583;
IPR029058;IPR005152;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
MT1628
false
Mycobacterium tuberculosis
523
row_413506
false
null
81,802
P9WKB5
MKLLSPLDQMFARMEAPRTPMHIGAFAVFDLPKGAPRRFIRDLYEAISQLAFLPFPFDSVIAGGASMAYWRQVQPDPSYHVRLSALPYPGTGRDLGALVERLHSTPLDMAKPLWELHLIEGLTGRQFAMYFKAHHCAVDGLGGVNLIKSWLTTDPEAPPGSGKPEPFGDDYDLASVLAAATTKRAVEGVSAVSELAGRLSSMVLGANSSVRAALTTPRTPFNTRVNRHRRLAVQVLKLPRLKAVAHATDCTVNDVILASVGGACRRYLQELGDLPTNTLTASVPVGFERDADTVNAASGFVAPLGTSIEDPVARLTTISASTTRGKAELLAMSPNALQHYSVFGLLPIAVGQKTGALGVIPPLFNFTVSNVVLSKDPLYLSGAKLDVIVPMSFLCDGYGLNVTLVGYTDKVVLGFLGCRDTLPHLQRLAQYTGAAFEELETAALP
Putative diacyglycerol O-acyltransferase Rv2285 (EC 2.3.1.20) (Putative triacylglycerol synthase Rv2285)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
445
47,707
Acyltransferase;Glycerol metabolism;Lipid biosynthesis;Lipid metabolism;Reference proteome;Transferase
GO:0001666; GO:0004144; GO:0005886; GO:0006071; GO:0008374; GO:0019432; GO:0045017; GO:0051701; GO:0071731
Evidence at protein level
4
null
null
null
PF06974;PF03007;
IPR014292;IPR045034;IPR009721;IPR004255;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
Rv2285 MTCY339.25c
false
Mycobacterium tuberculosis
524
row_72248
false
null
207,768
P65568
MTTQATPLTPVISRHWDDPESWTLATYQRHDRYRGYQALQKALTMPPDDVISIVKDSGLRGRGGAGFATGTKWSFIPQGDTGAAAKPHYLVVNADESEPGTCKDIPLMLATPHVLIEGVIIAAYAIRAHHAFVYVRGEVVPVLRRLHNAVAEAYAAGFLGRNIGGSGFDLELVVHAGAGAYICGEETALLDSLEGRRGQPRLRPPFPAVAGLYGCPTVINNVETIASVPSIILGGIDWFRSMGSEKSPGFTLYSLSGHVTRPGQYEAPLGITLRELLDYAGGVRAGHRLKFWTPGGSSTPLLTDEHLDVPLDYEGVGAAGSMLGTKALEIFDETTCVVRAVRRWTEFYKHESCGKCTPCREGTFWLDKIYERLETGRGSHEDIDKLLDISDSILGKSFCALGDGAASPVMSSIKHFRDEYLAHVEGGGCPFDPRDSMLVANGVDA
NADH-quinone oxidoreductase subunit F (EC 7.1.1.-) (NADH dehydrogenase I subunit F) (NDH-1 subunit F)
Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
233,413
445
48,102
4Fe-4S;Flavoprotein;FMN;Iron;Iron-sulfur;Metal-binding;NAD;Quinone;Reference proteome;Translocase
GO:0008137; GO:0010181; GO:0045333; GO:0046872; GO:0048038; GO:0051287; GO:0051539
Inferred from homology
3
null
null
null
PF01512;PF10589;PF10531;
IPR050837;IPR001949;IPR011537;IPR011538;IPR037225;IPR019575;IPR037207;IPR019554;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species), Mycobacterium bovis (biotype)
nuoF BQ2027_MB3174
false
Mycobacterium tuberculosis
525
row_194190
false
null
431,691
P9WJW6
MSRDPTGVGARWAIMIVSLGVTASSFLFINGVAFLIPRLENARGTPLSHAGLLASMPSWGLVVTMFAWGYLLDHVGERMVMAVGSALTAAAAYAAASVHSLLWIGVFLFLGGMAAGGCNSAGGRLVSGWFPPQQRGLAMGIRQTAQPLGIASGALVIPELAERGVHAGLMFPAVVCTLAAVASVLGIVDPPRKSRTKASEQELASPYRGSSILWRIHAASALLMMPQTVTVTFMLVWLINHHGWSVAQAGVLVTISQLLGALGRVAVGRWSDHVGSRMRPVRLIAAAAAATLFLLAAVDNEGSRYDVLLMIAISVIAVLDNGLEAAAITEYAGPYWSGRALGIQNTTQRLMAAAGPPLFGSLITTAAYPTAWALCGVFPLAAVPLVPVRLLPPGLETRARRQSVRRHRWWQAVRCHAWPNGPRRPGPPGQPRRVRQGGTAITPPT
Uncharacterized MFS-type transporter MT3072
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
83,331
445
47,016
Cell membrane;Membrane;Reference proteome;Transmembrane;Transmembrane helix;Transport
GO:0005886; GO:0022857
Inferred from homology
2
SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
null
TRANSMEM 16..36; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 52..72; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 98..118; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 168..188; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 219..239; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 243..263; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 283..303; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 366..386; /note="Helical"; /evidence="ECO:0000255"
PF07690;
IPR011701;IPR052952;IPR020846;IPR036259;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
MT3072
false
Mycobacterium tuberculosis
526
row_413446
false
null
26,992
P9WNW9
MTAPPPVLTRIDLRGAELTAAELRAALPRGGADVEAVLPTVRPIVAAVAERGAEAALDFGASFDGVRPHAIRVPDAALDAALAGLDCDVCEALQVMVERTRAVHSGQRRTDVTTTLGPGATVTERWVPVERVGLYVPGGNAVYPSSVVMNVVPAQAAGVDSLVVASPPQAQWDGMPHPTILAAARLLGVDEVWAVGGAQAVALLAYGGTDTDGAALTPVDMITGPGNIYVTAAKRLCRSRVGIDAEAGPTEIAILADHTADPVHVAADLISQAEHDELAASVLVTPSEDLADATDAELAGQLQTTVHRERVTAALTGRQSAIVLVDDVDAAVLVVNAYAAEHLEIQTADAPQVASRIRSAGAIFVGPWSPVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRGIHVVEYTEAALKDVSGHVITLATAEDLPAHGEAVRRRFER
Histidinol dehydrogenase (HDH) (EC 1.1.1.23)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
444
45,941
Amino-acid biosynthesis;Direct protein sequencing;Histidine biosynthesis;Metal-binding;NAD;Oxidoreductase;Reference proteome;Zinc
GO:0000105; GO:0004399; GO:0005737; GO:0005829; GO:0008270; GO:0009274; GO:0051287
Evidence at protein level
5
null
null
null
PF00815;
IPR016161;IPR001692;IPR022695;IPR012131;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
hisD Rv1599 MTCY336.05c
false
Mycobacterium tuberculosis
527
row_23631
false
null
431,765
P9WKH6
MRNVRLFRALLGVDKRTVIEDIEFEEDDAGDGARVIARVRPRSAVLRRCGRCGRKASWYDRGAGLRQWRSLDWGTVEVFLEAEAPRVNCPTHGPTVVAVPWARHHAGHTYAFDDTVAWLAVACSKTAVCELMRIAWRTVGAIVARVWADTEKRIDRFANLRRIGIDEISYKRHHRYLTVVVDHDSGRLVWAAPGHDKATLGLFFDALGAERAAQITHVSADAADWIADVVTERCPDAIQCADPFHVVAWATEALDVERRRAWNDARAIARTEPKWGRGRPGKNAAPRPGRERARRLKGARYALWKNPEDLTERQSAKLAWIAKTDPRLYRAYLLKESLRHVFSVKGEEGKQALDRWISWAQRCRIPVFVELAARIKRHRVAIDAALDHGLSQGLIESTNTKIRLLTRIAFGFRSPQALIALAMLTLAGHRPTLPGRHNHPQISQ
Transposase for insertion sequence element IS1557
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
83,331
444
50,186
DNA recombination;DNA-binding;Reference proteome;Transposable element;Transposition
GO:0003677; GO:0006310; GO:0032196
Inferred from homology
2
null
null
null
PF01610;PF13542;PF14690;
IPR047951;IPR002560;IPR032877;IPR029261;
null
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
MT1353; MT3905
false
Mycobacterium tuberculosis
528
row_413520
false
null
27,047
P9WQ35
MAARKCGAPPIAADGSTRRPDCVTAVRTQARAPTQHYAESVARRQRVLTITAWLAVVVTGSFALMQLATGAGGWYIALINVFTAVTFAIVPLLHRFGGLVAPLTFIGTAYVAIFAIGWDVGTDAGAQFFFLVAAALVVLLVGIEHTALAVGLAAVAAGLVIALEFLVPPDTGLQPPWAMSVSFVLTTVSACGVAVATVWFALRDTARAEAVMEAEHDRSEALLANMLPASIAERLKEPERNIIADKYDEASVLFADIVGFTERASSTAPADLVRFLDRLYSAFDELVDQHGLEKIKVSGDSYMVVSGVPRPRPDHTQALADFALDMTNVAAQLKDPRGNPVPLRVGLATGPVVAGVVGSRRFFYDVWGDAVNVASRMESTDSVGQIQVPDEVYERLKDDFVLRERGHINVKGKGVMRTWYLIGRKVAADPGEVRGAEPRTAGV
Adenylate cyclase (EC 4.6.1.1) (ATP pyrophosphate-lyase) (Adenylyl cyclase)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
83,332
443
47,370
3D-structure;ATP-binding;cAMP biosynthesis;Cell membrane;Lyase;Magnesium;Manganese;Membrane;Metal-binding;Nucleotide-binding;Reference proteome;Transmembrane;Transmembrane helix
GO:0000287; GO:0001653; GO:0004016; GO:0004383; GO:0005524; GO:0005886; GO:0006171; GO:0006182; GO:0007168; GO:0030145; GO:0035556
Evidence at protein level
5
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:11431477, ECO:0000269|PubMed:11447108}; Multi-pass membrane protein {ECO:0000305}.
null
TRANSMEM 47..69; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 74..93; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 98..120; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 124..143; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 148..167; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 180..202; /note="Helical"; /evidence="ECO:0000255"
PF00211;PF20967;
IPR001054;IPR018297;IPR050401;IPR048432;IPR029787;
1YK9;4P2F;4P2M;4P2X;7YZ9;7YZI;7YZK;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
cya Rv1625c MTCY01B2.17c
false
Mycobacterium tuberculosis
529
row_23686
false
null