Datasets:
manufernandezbur
/
tox_nontox_clustered_2025

Dataset card Data Studio Files Community
1
Unnamed: 0
int64
2
562k
Entry
stringlengths
6
10
Sequence
stringlengths
11
999
Protein names
stringlengths
5
558
Organism
stringclasses
392 values
Organism (ID)
int64
595
2.89M
Length
int64
11
999
Mass
int64
1.06k
118k
Keywords
stringlengths
4
380
⌀
Gene Ontology IDs
stringlengths
10
754
⌀
Protein existence
stringclasses
5 values
Annotation
float64
1
5
Subcellular location [CC]
stringlengths
30
2.26k
⌀
Signal peptide
stringclasses
677 values
Transmembrane
stringlengths
32
2.52k
⌀
Pfam
stringlengths
8
72
⌀
InterPro
stringlengths
10
180
⌀
PDB
stringlengths
5
2.65k
⌀
Taxonomic lineage
stringclasses
178 values
Gene Names
stringlengths
2
299
⌀
Toxin
bool
2 classes
species
stringclasses
111 values
cdhit_cluster
int64
0
4.65k
cdhit_rep
stringlengths
5
10
cdhit_rep_is_ref
bool
1 class
cdhit_pct_id
float64
2,245
Q9I788
MHIQSSQQNPSFVAELSQAVAGRLGQVEARQVATPREAQQLAQRQEAPKGEGLLSRLGAALARPFVAIIEWLGKLLGSRAHAATQAPLSRQDAPPAASLSAAEIKQMMLQKALPLTLGGLGKASELATLTAERLAKDHTRLASGDGALRSLATALVGIRDGSRIEASRTQAARLLEQSVGGIALQQWGTAGGAASQHVLSASPEQLREIAVQLHAVMDKVALLRHAVESEVKGEPVDKALADGLVEHFGLEAEQYLGEHPDGPYSDAEVMALGLYTNGEYQHLNRSLRQGRELDAGQALIDRGMSAAFEKSGPAEQVVKTFRGTQGRDAFEAVKEGQVGHDAGYLSTSRDPGVARSFAGQGTITTLFGRSGIDVSEISIEGDEQEILYDKGTDMRVLLSAKDGQGVTRRVLEEATLGERSGHGEGLLDALDLATGTDRSGKPQEQDLRLRMRGLDLA
Exoenzyme T [Includes: GTPase-activating protein (GAP); ADP-ribosyltransferase (ADPRT) (EC 2.4.2.31)]
Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
208,964
457
48,515
3D-structure;Glycosyltransferase;GTPase activation;Nucleotidyltransferase;Reference proteome;Secreted;Toxin;Transferase;Virulence
GO:0005096; GO:0005576; GO:0016779; GO:0090729; GO:0106274; GO:0141029
Evidence at protein level
4
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:24387107}. Note=Secreted via type III secretion system (T3SS) and delivered into the host cytoplasm. {ECO:0000305}.
null
null
PF03496;PF03545;
IPR003540;IPR050999;IPR003537;IPR014773;IPR037168;
4JMF;6GNN;6JNP;
cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Gammaproteobacteria (class), Pseudomonadales (order), Pseudomonadaceae (family), Pseudomonas (genus), Pseudomonas aeruginosa group (no rank), Pseudomonas aeruginosa (species)
exoT PA0044
true
Pseudomonas aeruginosa
2
row_2161
false
null
2,948
G3XDA1
MHIQSLQQSPSFAVELHQAASGRLGQIEARQVATPSEAQQLAQRQDAPKGEGLLARLGAALVRPFVAIMDWLGKLLGSHARTGPQPSQDAQPAVMSSAVVFKQMVLQQALPMTLKGLDKASELATLTPEGLAREHSRLASGDGALRSLSTALAGIRAGSQVEESRIQAGRLLERSIGGIALQQWGTTGGAASQLVLDASPELRREITDQLHQVMSEVALLRQAVESEVSRVSADKALADGLVKRFGADAEKYLGRQPGGIHSDAEVMALGLYTGIHYADLNRALRQGQELDAGQKLIDQGMSAAFEKSGQAEQVVKTFRGTRGGDAFNAVEEGKVGHDDGYLSTSLNPGVARSFGQGTISTVFGRSGIDVSGISNYKNEKEILYNKETDMRVLLSASDEQGVTRRVLEEAALGEQSGHSQGLLDALDLASKPERSGEVQEQDVRLRMRGLDLA
Secreted exoenzyme S [Includes: GTPase-activating protein (GAP); ADP-ribosyltransferase (ADPRT) (EC 2.4.2.31)]
Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
208,964
453
48,302
3D-structure;Glycosyltransferase;GTPase activation;Nucleotidyltransferase;Reference proteome;Secreted;Toxin;Transferase;Virulence
GO:0005096; GO:0005576; GO:0016779; GO:0090729; GO:0106274
Evidence at protein level
3
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:26090668}. Note=Secreted via type III secretion system (T3SS) and delivered into the host cytoplasm. {ECO:0000305}.
null
null
PF03496;PF03545;
IPR003540;IPR050999;IPR003537;IPR014773;IPR037168;
6Y7T;
cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Gammaproteobacteria (class), Pseudomonadales (order), Pseudomonadaceae (family), Pseudomonas (genus), Pseudomonas aeruginosa group (no rank), Pseudomonas aeruginosa (species)
exoS PA3841
true
Pseudomonas aeruginosa
3
row_2852
false
null
362
P13128
MKKIMLVFITLILVSLPIAQQTEAKDASAFNKENSISSMAPPASPPASPKTPIEKKHADEIDKYIQGLDYNKNNVLVYHGDAVTNVPPRKGYKDGNEYIVVEKKKKSINQNNADIQVVNAISSLTYPGALVKANSELVENQPDVLPVKRDSLTLSIDLPGMTNQDNKIVVKNATKSNVNNAVNTLVERWNEKYAQAYPNVSAKIDYDDEMAYSESQLIAKFGTAFKAVNNSLNVNFGAISEGKMQEEVISFKQIYYNVNVNEPTRPSRFFGKAVTKEQLQALGVNAENPPAYISSVAYGRQVYLKLSTNSHSTKVKAAFDAAVSGKSVSGDVELTNIIKNSSFKAVIYGGSAKDEVQIIDGNLGDLRDILKKGATFNRETPGVPIAYTTNFLKDNELAVIKNNSEYIETTSKAYTDGKINIDHSGGYVAQFNISWDEVNYDPEGNEIVQHKNWSENNKSKLAHFTSSIYLPGNARNINVYAKECTGLAWEWWRTVIDDRNLPLVKNRNISIWGTTLYPKYSNKVDNPIE
Listeriolysin O (LLO) (Thiol-activated cytolysin)
Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e)
169,963
529
58,688
3D-structure;Cytolysis;Hemolysis;Host cell membrane;Host membrane;Lipid-binding;Membrane;Phosphoprotein;Reference proteome;Secreted;Signal;Toxin;Transmembrane;Transmembrane beta strand;Ubl conjugation;Virulence
GO:0005576; GO:0015485; GO:0016020; GO:0020002; GO:0031640; GO:0042802; GO:0044658; GO:0090729; GO:0141160
Evidence at protein level
5
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:24751541, ECO:0000269|PubMed:3110067}. Host membrane {ECO:0000269|PubMed:24751541, ECO:0000269|PubMed:3110067}; Multi-pass membrane protein {ECO:0000269|PubMed:3110067}. Host cell membrane {ECO:0000269|PubMed:3110067}; Multi-pass membrane protein {ECO:0000269|PubMed:3110067}. Note=Secreted as soluble protein that then inserts into the host membrane and forms pores formed by transmembrane beta-strands. {ECO:0000305|PubMed:24751541}.
SIGNAL 1..24; /evidence="ECO:0000255"
TRANSMEM 214..227; /note="Beta stranded"; /evidence="ECO:0000250|UniProtKB:Q04IN8"; TRANSMEM 234..243; /note="Beta stranded"; /evidence="ECO:0000250|UniProtKB:Q04IN8"; TRANSMEM 312..321; /note="Beta stranded"; /evidence="ECO:0000250|UniProtKB:Q04IN8"; TRANSMEM 329..341; /note="Beta stranded"; /evidence="ECO:0000250|UniProtKB:Q04IN8"
PF17440;PF01289;
IPR035390;IPR038700;IPR001869;IPR036363;IPR036359;
4CDB;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Bacillota (phylum), Bacilli (class), Bacillales (order), Listeriaceae (family), Listeria (genus), Listeria monocytogenes (species)
hly hlyA lisA lmo0202
true
Listeria monocytogenes
0
row_335
false
null
377
P17347
IGIAYNRGMCDPKKSVGTVMDHSTEHLSVAVAMAHEMGHNLGMDHDGNQCNCGGAGCVMSEELIESRSYKFSDCSKNQYQNYLTIYKPQCILNQPLRTDTVSTPVSGNELLQNSANPCYDPLTCHPREGEQCESGPCCRNCKFLKEGTICKRARGDDMDDYCNGKTCDCPRNPHKGPATAKGSVLM
Disintegrin metalloproteinase/disintegrin echistatin [Cleaved into: Snake venom metalloproteinase (SVMP) (EC 3.4.24.-); Disintegrin echistatin (Ech) (Carinatin) (Disintegrin echistatin-alpha-1) (Platelet aggregation activation inhibitor); Disintegrin echistatin-alpha-2]
Echis carinatus sochureki (Saw-scaled viper)
124,223
186
20,364
3D-structure;Cell adhesion impairing toxin;Direct protein sequencing;Disulfide bond;Hemostasis impairing toxin;Hydrolase;Metal-binding;Metalloprotease;Pharmaceutical;Platelet aggregation inhibiting toxin;Protease;Pyrrolidone carboxylic acid;Secreted;Toxin;Zinc
GO:0004222; GO:0005576; GO:0005886; GO:0006508; GO:0046872; GO:0090729
Evidence at protein level
5
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:2320569, ECO:0000269|PubMed:3198653}.
null
null
PF00200;PF01421;
IPR018358;IPR001762;IPR036436;IPR024079;IPR001590;IPR034027;
1RO3;2ECH;6LSQ;
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Viperidae (family), Viperinae (subfamily), Echis (genus), Echis carinatus (species)
null
true
Echis carinatus
0
row_348
false
null
7,255
Q6X5S6
MGRFIFVSFSLLVVFFSLSGTEAGVCCPLGWSGYDQNCYKAFEELMNWADAEKFCTQQHKGSHLVSLHNIAEADFVVKKIVSVLKDGVIWMGLNDVWNECNWGWTDGAQLDYKAWNVESNCFIFKTADKPLVTYGLQWDTQFRLQEPG
Snaclec 8 (C-type lectin 8) (CTL-8)
Echis carinatus sochureki (Saw-scaled viper)
124,223
148
16,879
Disulfide bond;Hemostasis impairing toxin;Secreted;Signal;Toxin
GO:0005576; GO:0090729
Evidence at transcript level
2
SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
SIGNAL 1..23; /evidence="ECO:0000255"
null
PF00059;
IPR001304;IPR016186;IPR050111;IPR016187;
null
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Viperidae (family), Viperinae (subfamily), Echis (genus), Echis carinatus (species)
null
true
Echis carinatus
1
row_6976
false
null
7,257
Q6X5S8
WGDSSSSASACWSCSSPLSGTEAGVCCPLGWSGYDQNCYKAFEELMNWADAEKFCTQQHKGSHLVSLHNIAEADFVVKKIVSVLKDGVIWMGLNDVWNECNWGWTDGAQLDYKAWNVESNCFIFKTAENHWSRTDCSGTHSFVCKSPA
Snaclec 3 (C-type lectin 3) (CTL-3)
Echis carinatus sochureki (Saw-scaled viper)
124,223
148
16,445
Disulfide bond;Hemostasis impairing toxin;Secreted;Signal;Toxin
GO:0005576; GO:0090729
Evidence at transcript level
2
SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
SIGNAL <1..23; /evidence="ECO:0000255"
null
PF00059;
IPR001304;IPR016186;IPR050111;IPR018378;IPR016187;
null
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Viperidae (family), Viperinae (subfamily), Echis (genus), Echis carinatus (species)
null
true
Echis carinatus
2
row_6978
false
null
7,258
Q6X5S9
MGRFIFVSFGLLVVFLSLSGTEAGVCCPLGWSGYDQNCYKAFEELMNWADAEKFCTQQHKGSHLVSLHNIAEADFVVKKIVSVLKDGVIWMGLNDVWNECNWGWTDGAQLDYKAWNVESNCFIFKTAENHWSRTDCSGTHSFVCKSPA
Snaclec 1 (C-type lectin 1) (CTL-1)
Echis carinatus sochureki (Saw-scaled viper)
124,223
148
16,673
Disulfide bond;Hemostasis impairing toxin;Secreted;Signal;Toxin
GO:0005576; GO:0090729
Evidence at transcript level
2
SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
SIGNAL 1..23; /evidence="ECO:0000255"
null
PF00059;
IPR001304;IPR016186;IPR050111;IPR018378;IPR016187;
null
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Viperidae (family), Viperinae (subfamily), Echis (genus), Echis carinatus (species)
null
true
Echis carinatus
3
row_6979
false
null
7,253
Q6X5S4
MGRFIFISFGLLVVFLSLSGTEAECLPDWFHYEGHCYRVFDEPKTWADAEKFCSEQANGGHLVSVHSKKEAGLVGVLAYQTLESPIVWMGLSKIWNQCDWTWTNGAKLKYEAWAEESYCIHITSKKKEWKSLPCRNYGHFVCKSPA
Snaclec 9 (C-type lectin 9) (CTL-9)
Echis carinatus sochureki (Saw-scaled viper)
124,223
146
16,733
Disulfide bond;Hemostasis impairing toxin;Secreted;Signal;Toxin
GO:0005576; GO:0090729
Evidence at transcript level
2
SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
SIGNAL 1..23; /evidence="ECO:0000255"
null
PF00059;
IPR001304;IPR016186;IPR050111;IPR018378;IPR016187;
null
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Viperidae (family), Viperinae (subfamily), Echis (genus), Echis carinatus (species)
null
true
Echis carinatus
4
row_6974
false
null
4,208
P81017
DQDCLSGWSFYEGHCYQLFRLKTWDEAEKYCNQWDGGHLVSIESNAKAEFVAQLISRKLPKSAIEDRVWIGLRDRSKREQCGHLWTDNSFVHYEHVVPPTKCFVLERQTEFRKWIAVNCEFKFPFVCKAKIPR
Snaclec echicetin subunit alpha
Echis carinatus sochureki (Saw-scaled viper)
124,223
133
15,803
Direct protein sequencing;Disulfide bond;Hemostasis impairing toxin;Platelet aggregation activating toxin;Secreted;Toxin
GO:0005576; GO:0090729
Evidence at protein level
3
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:9163349}.
null
null
PF00059;
IPR001304;IPR016186;IPR050111;IPR016187;
null
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Viperidae (family), Viperinae (subfamily), Echis (genus), Echis carinatus (species)
null
true
Echis carinatus
5
row_4043
false
null
4,235
P81996
NCLPDWSVYEGYCYKVFKERMNWADAEKFCMKQVKDGHLVSFRNSKEVDFMISLAFPMLKMELVWIGLSDYWRDCYWEWSDGAQLDYKAWDNERHCFAAKTTDNQWMRRKCSGEFYFVCKCPA
Snaclec echicetin subunit beta
Echis carinatus sochureki (Saw-scaled viper)
124,223
123
14,869
Direct protein sequencing;Disulfide bond;Hemostasis impairing toxin;Platelet aggregation inhibiting toxin;Secreted;Toxin
GO:0005576; GO:0090729
Evidence at protein level
3
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:7999097}.
null
null
PF00059;
IPR001304;IPR016186;IPR050111;IPR018378;IPR016187;
null
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Viperidae (family), Viperinae (subfamily), Echis (genus), Echis carinatus (species)
null
true
Echis carinatus
6
row_4068
false
null
1,550
P0DMT2
SIVELGKMIIQETGKSPFPSYTSYGCFCGGGERGPPLDATDRCCLAHSCCYDTLPDCSPKTDRYKYKRENGEIICENSTSCKKRICECDKAMAVCLRKNLNTYNKKYTYYPNFWCKGDIEKC
Phospholipase A2 homolog ECS_00014 (svPLA2 homolog)
Echis carinatus sochureki (Saw-scaled viper)
124,223
122
13,865
Disulfide bond;Myotoxin;Secreted;Toxin
GO:0005509; GO:0005543; GO:0005576; GO:0006644; GO:0016042; GO:0042130; GO:0047498; GO:0050482; GO:0090729
Evidence at protein level
4
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:23747272}.
null
null
PF00068;
IPR001211;IPR033112;IPR016090;IPR036444;IPR033113;
null
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Viperidae (family), Viperinae (subfamily), Echis (genus), Echis carinatus (species)
null
true
Echis carinatus
7
row_1484
false
null
4,249
P82465
MIQVLLVIICLAVFPYQGSSIILESGNINDYEIVYPKKVAVLPTGAMNSVHPCCDPVTCEPREGEHCISGPCCRNCKFLNAGTICKKAMLDGLNDYCTGISSDCPRNRYKGKEDD
Disintegrin EC6 subunit alpha (EC6A)
Echis carinatus sochureki (Saw-scaled viper)
124,223
115
12,578
Cell adhesion impairing toxin;Direct protein sequencing;Disulfide bond;Secreted;Signal;Toxin
GO:0005576; GO:0090729
Evidence at protein level
3
SUBCELLULAR LOCATION: Secreted.
SIGNAL 1..20; /evidence="ECO:0000255"
null
PF00200;
IPR018358;IPR001762;IPR036436;
null
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Viperidae (family), Viperinae (subfamily), Echis (genus), Echis carinatus (species)
null
true
Echis carinatus
8
row_4082
false
null
4,250
P82466
NSVHPCCDPVTCKPKRGKHCASGPCCENCYIVGVGTVCNPARGDWNDDNCTGVSSDCPPNPWNGKPSDN
Disintegrin EC6 subunit beta (EC6B)
Echis carinatus sochureki (Saw-scaled viper)
124,223
69
7,279
Cell adhesion impairing toxin;Direct protein sequencing;Disulfide bond;Secreted;Toxin
GO:0005576; GO:0090729
Evidence at protein level
3
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:10926928}.
null
null
PF00200;
IPR018358;IPR001762;IPR036436;
null
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Viperidae (family), Viperinae (subfamily), Echis (genus), Echis carinatus (species)
null
true
Echis carinatus
9
row_4083
false
null
2,266
Q9PSN7
LGTDIISPPVCGNELLEVGEECDCGFPRNCRDPCCDATTCKLHSWVECESGECCGQCKFTSAGNECRPARSECDIAESCTGQSADCPMDDFHRNGQPCLNNFGYCYNGNCPILYHQCYALFGSNVYEAEDSCFERNQKGDDDGYCRKENGEKIPCAPEDVKCGRLYCKDNSPGPNDSCKTFNSNEDDHKEMVLPGTKCADGKVCSNGHCVDVASAY
Snake venom metalloproteinase HT-1 (SVMP) (EC 3.4.24.-) (Hemorrhagic metalloproteinase HT-1) (Hemorrhagic toxin I)
Crotalus ruber ruber (Red diamond rattlesnake)
8,736
216
23,601
Calcium;Direct protein sequencing;Disulfide bond;Glycoprotein;Hemorrhagic toxin;Hemostasis impairing toxin;Hydrolase;Metal-binding;Metalloprotease;Protease;Secreted;Toxin;Zinc
GO:0005576; GO:0005886; GO:0006508; GO:0007596; GO:0008237; GO:0046872; GO:0090729
Evidence at protein level
4
SUBCELLULAR LOCATION: Secreted.
null
null
PF08516;PF00200;
IPR006586;IPR018358;IPR001762;IPR036436;
null
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Viperidae (family), Crotalinae (subfamily), Crotalus (genus), Crotalus ruber (species)
null
true
Crotalus ruber
0
row_2182
false
null
391
P20897
QNLPQSYIELVVVADHRMFMKYNSDLNTIRTRVHEIVNFINEFYRSLNIRVSLTDLEIWSDQDFITVQSSAKNTLHSFGEWRKSVLLNRKRHDNAQLLTAIVLDDYTLGLAYLNSMCHPRNSVGLIQDHSPINLLMGVTMAHELGHNLGMEHDGKDCLRGASLCIMRPGLTPGRSYEFSDASMRYYQKFLDQYKPQCILNKP
Snake venom metalloproteinase HT-2 (SVMP) (EC 3.4.24.48) (Hemorrhagic metalloproteinase HT-2) (Hemorrhagic toxin II) (Ruberlysin)
Crotalus ruber ruber (Red diamond rattlesnake)
8,736
202
23,321
Calcium;Direct protein sequencing;Disulfide bond;Hemorrhagic toxin;Hemostasis impairing toxin;Hydrolase;Metal-binding;Metalloprotease;Protease;Pyrrolidone carboxylic acid;Secreted;Toxin;Zinc
GO:0004222; GO:0005576; GO:0005886; GO:0006508; GO:0046872; GO:0090729
Evidence at protein level
5
SUBCELLULAR LOCATION: Secreted.
null
null
PF01421;
IPR024079;IPR001590;IPR034027;
null
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Viperidae (family), Crotalinae (subfamily), Crotalus (genus), Crotalus ruber (species)
null
true
Crotalus ruber
1
row_359
false
null
2,963
H9M5U4
NPCCDAATCKMRPGSQCAEGLCCDQCRFMKKGTVCRVSMVDRNDDTCTGLSADCPRNGLYG
Disintegrin rubistatin
Crotalus ruber ruber (Red diamond rattlesnake)
8,736
61
6,558
Cell adhesion impairing toxin;Disulfide bond;Hemostasis impairing toxin;Platelet aggregation inhibiting toxin;Secreted;Toxin
GO:0005576; GO:0005886; GO:0090729
Evidence at transcript level
3
SUBCELLULAR LOCATION: Secreted {ECO:0000305|PubMed:22192732}.
null
null
PF00200;
IPR018358;IPR001762;IPR036436;
null
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Viperidae (family), Crotalinae (subfamily), Crotalus (genus), Crotalus ruber (species)
null
true
Crotalus ruber
2
row_2866
false
null
2,730
C5H5D5
EQQRYLNAKKYVKLVLVADYIMYLKYGRSLTTLRTRMYDIVNIINLIFQRMNIHVALVGLEIWSNRDKIIVQSSADVTLDLFAKWRETDLLKRKSHDNAQLLTGINFNGPTAGLAYLSGICKPMYSAGIVQDHNKVHHLVAIAMAHEMGHNLGMDHDKDTCTCGARSCVMAGTLSCEPSYLFSDCSRREHRAFLIKDMPQCILEKPLRTDVVSPPVCGNYFVEVGEECDCGFSATCRDTCCDAATCKLRQGAQCAEGLCCDQCRFKGAGTECRAAKDECDMADLCTGRSAECTDRFQRNGQPCQNNNGYCYNGTCPIMRDQCIALFGPNAAVSQDACFQFNLQGNHYGYCRKEQNTKIACEPQDVKCGRLYCFPSSPATKNPCNIHYSPNDEDKGMVLPGTKCADGKACSNGRCVDVNTPY
Zinc metalloproteinase-disintegrin-like lachestatin-1 (EC 3.4.24.-) (Snake venom metalloprotease) (SVMP) (Vascular apoptosis-inducing protein-like) (VAP-like)
Lachesis muta rhombeata (Bushmaster)
60,219
421
46,799
Apoptosis;Calcium;Cell adhesion impairing toxin;Disulfide bond;Fibrinogenolytic toxin;Glycoprotein;Hemorrhagic toxin;Hemostasis impairing toxin;Hydrolase;Metal-binding;Metalloprotease;Protease;Secreted;Toxin;Zinc
GO:0004222; GO:0005576; GO:0005886; GO:0006508; GO:0006915; GO:0046872; GO:0090729
Evidence at transcript level
3
SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
null
null
PF08516;PF00200;PF01421;
IPR006586;IPR018358;IPR001762;IPR036436;IPR024079;IPR001590;IPR034027;
null
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Viperidae (family), Crotalinae (subfamily), Lachesis (genus), Lachesis muta (species)
null
true
Lachesis muta
0
row_2638
false
null
615
Q27J47
MVLITVLANLLILQLSYAQKSSKLVFGGDECNINEHRSLVVLFNSSGFLCAGTLINKEWVLTAAHCDSENFQMQLGVHSKKVPNKDEETRDPKEKFICPNRKKNDEKDKDIMLIRLNRPVSNSEHIALLSLPSSPPSVGSVCRIMGWGTISPTKEIYPDVPHCADINILDHAVCRAAYSGWLATSTTLCAGILEGGKDSCHGDSGGPLICNGQFQGIVSLGRHPCGHPDEPGVYTKVFDYTDWIQSIIAGNTDAACPP
Venom plasminogen activator LV-PA (EC 3.4.21.-) (LMUT0402S) (Plasminogen activating proteinase) (Snake venom serine protease) (SVSP)
Lachesis muta muta (Bushmaster)
8,753
258
28,062
Direct protein sequencing;Disulfide bond;Fibrinolytic toxin;Glycoprotein;Hemostasis impairing toxin;Hydrolase;Hypotensive agent;Plasminogen activation;Protease;Secreted;Serine protease;Signal;Toxin
GO:0004252; GO:0005576; GO:0006508; GO:0008217; GO:0030141; GO:0090729
Evidence at protein level
5
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:17034951}.
SIGNAL 1..18; /evidence="ECO:0000255"
null
PF00089;
IPR009003;IPR043504;IPR001314;IPR001254;IPR018114;IPR033116;
null
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Viperidae (family), Crotalinae (subfamily), Lachesis (genus), Lachesis muta (species)
null
true
Lachesis muta
1
row_575
false
null
616
Q27J49
MFVSRLAASGLLLLALLAVSLDGKPVQQWSHKGWPPRPQIPPLVVQQWSQKPWPPGHHIPPVVVQEWPPGHHIPPLVVQQWSQKKWPPGHHIPPLVVQKWDPPPISPPLLKPHESPAGGTTALREELSLGPEAALDTPPAGPDVGPRGSKAPAAPHRLPKSKGASATSAASRPMRDLRTDGKQARQNWGRMMNPDHHAVGGGGGGGGARRLKGLAKKRVGDGCFGLKLDRIGSMSGLGC
Bradykinin-potentiating and C-type natriuretic peptides (BPP-CNP) [Cleaved into: Bradykinin-potentiating peptide 1 (BPP-1) (Lm-BPP 1) (LmrBPP9); Bradykinin-potentiating peptide 2 (BPP-2) (Lm-BPP 2); Bradykinin-potentiating peptide 3 (BPP-3) (Lm-BPP 3); Bradykinin-potentiating peptide 4 (BPP-4) (Lm-BPP 4); Bradykinin-potentiating peptide 5 (BPP-5) (Lm-BPP 5); Bradykinin inhibitory peptide (BIP) (Bradykinin inhibitor peptide); C-type natriuretic peptide (CNP) (Lm-CNP)]
Lachesis muta muta (Bushmaster)
8,753
239
25,453
Cleavage on pair of basic residues;Direct protein sequencing;Disulfide bond;Hypotensive agent;Metalloenzyme inhibitor;Metalloprotease inhibitor;Protease inhibitor;Pyrrolidone carboxylic acid;Secreted;Signal;Toxin;Vasoactive;Vasodilator
GO:0005179; GO:0005576; GO:0006182; GO:0007168; GO:0008217; GO:0030414; GO:0042311; GO:0090729
Evidence at protein level
5
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:15876444, ECO:0000269|PubMed:16277978, ECO:0000269|PubMed:29410030}.
SIGNAL 1..23; /evidence="ECO:0000255"
null
PF00212;
IPR000663;IPR030480;
null
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Viperidae (family), Crotalinae (subfamily), Lachesis (genus), Lachesis muta (species)
null
true
Lachesis muta
2
row_576
false
null
419
P33589
VIGGDECNINEHRFLVALYDGLSGTFLCGGTLINQEWVLTAQHCNRSLMNIYLGMHNKNVKFDDEQRRYPKKKYFFRCNKNFTKWDEDIRLNRPVRFSAHIEPLSLPSNPPSEDSVCRVMGWGQITSPPETLPDVPHCANINLFNYTVCRGAYPRMPTKVLCAGVLEGGIDTCNRDSGGPLICNGQFQGIVFWGPDPCAQPDKPGVYTKVFDYLDWIQSVIAGNTTCS
Thrombin-like enzyme gyroxin analog (LM-TL) (SVTLE) (EC 3.4.21.74) (Fibrinogen-clotting enzyme) (Snake venom serine protease) (SVSP) (Venombin A)
Lachesis muta muta (Bushmaster)
8,753
228
25,629
Blood coagulation cascade activating toxin;Direct protein sequencing;Disulfide bond;Glycoprotein;Hemostasis impairing toxin;Hydrolase;Protease;Secreted;Serine protease;Toxin
GO:0004252; GO:0005576; GO:0006508; GO:0030141; GO:0090729
Evidence at protein level
5
SUBCELLULAR LOCATION: Secreted.
null
null
PF00089;
IPR009003;IPR043504;IPR001314;IPR001254;
null
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Viperidae (family), Crotalinae (subfamily), Lachesis (genus), Lachesis muta (species)
null
true
Lachesis muta
3
row_383
false
null
6,999
Q27J48
MSPSAGFQFSLYFLQTKKVLWKLTGLCYILLFTLCFFADQENGGKALASPPGIWKRADVTFDSNTAFSSLVVSANKKTVKNVGVPQVVPDNPERFNSSPCVLGSPGFRSGKHYFEVKYGTQREWAVGLAGKSVKRKGNLNLVPEERIWQTGLWWLRHLETDPGRVHSTSGKITVFVDYSGGNVIFDLNRIITILKANFSGEEVVPFFYLGGTVSLTTL
Ohanin-like protein
Lachesis muta muta (Bushmaster)
8,753
218
24,179
Neurotoxin;Secreted;Signal;Toxin
GO:0005576; GO:0090729
Evidence at transcript level
2
SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
SIGNAL 1..40; /evidence="ECO:0000255"
null
PF13765;PF00622;
IPR001870;IPR043136;IPR003879;IPR013320;IPR006574;IPR003877;IPR050143;
null
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Viperidae (family), Crotalinae (subfamily), Lachesis (genus), Lachesis muta (species)
null
true
Lachesis muta
4
row_6721
false
null
393
P22796
FSQKYIELVVVADHGMFTKYNGNLNTIRTRVHEIVNTLNGFYRSLNILISLTDLEIWSNQDLINVQSAANDTLKTFGEWRERVLLNRISHDNAQLLTAIDLADNTIGIAYTGGMCYPKNSVGIVQDHSPKTLLIAVTMAHELGHNLGMKHDENHCHCSASFCIMPPSISEGPSYEFSDCSKDYYQMFLTKRKPQCILNKP
Snake venom metalloproteinase hemorrhagic factor 2 (SVMP) (EC 3.4.24.-) (Hemorrhagic factor II) (LHF-II) (LHFII)
Lachesis muta muta (Bushmaster)
8,753
200
22,596
Calcium;Direct protein sequencing;Disulfide bond;Glycoprotein;Hemorrhagic toxin;Hemostasis impairing toxin;Hydrolase;Metal-binding;Metalloprotease;Myotoxin;Protease;Secreted;Toxin;Zinc
GO:0004222; GO:0005576; GO:0005886; GO:0006508; GO:0008233; GO:0044358; GO:0044398; GO:0044522; GO:0044523; GO:0046872; GO:0090729
Evidence at protein level
5
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:10400290, ECO:0000269|PubMed:2026257}.
null
null
PF01421;
IPR024079;IPR001590;IPR034027;
null
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Viperidae (family), Crotalinae (subfamily), Lachesis (genus), Lachesis muta (species)
null
true
Lachesis muta
5
row_361
false
null
1,609
P0DUN7
SLVELGKMILQETGKNPVTSYGAYGCNCGVLGSGKPKDATDRCCYVHKCCYKKLTDCDPKKDRYSYSWKDKTIVCGENNSCLKELCECDKAVAICLRENLDTYNKKYNYLKPFCKKADPC
Basic phospholipase A2 homolog LmutTX (svPLA2 homolog) (LmmV toxin) (Lys49 PLA2-like)
Lachesis muta muta (Bushmaster)
8,753
120
13,538
Antibiotic;Antimicrobial;Direct protein sequencing;Disulfide bond;Myotoxin;Secreted;Toxin
GO:0005509; GO:0005543; GO:0005576; GO:0006644; GO:0016042; GO:0042130; GO:0042742; GO:0047498; GO:0050482; GO:0090729
Evidence at protein level
4
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:29067765}.
null
null
PF00068;
IPR001211;IPR033112;IPR016090;IPR036444;IPR033113;
null
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Viperidae (family), Crotalinae (subfamily), Lachesis (genus), Lachesis muta (species)
null
true
Lachesis muta
6
row_1542
false
null
3,974
P31990
EAGEECDCGAPANPCCDAATCKLRPGAQCAEGLCCDQCRFIKKGKICRRARGDNPDDRCTGQSADCPRNGYYG
Disintegrin lachesin (Platelet aggregation activation inhibitor)
Lachesis muta muta (Bushmaster)
8,753
73
7,765
Cell adhesion impairing toxin;Direct protein sequencing;Disulfide bond;Hemostasis impairing toxin;Platelet aggregation inhibiting toxin;Secreted;Toxin
GO:0005576; GO:0090729
Evidence at protein level
3
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:8419314}.
null
null
PF00200;
IPR018358;IPR001762;IPR036436;
null
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Viperidae (family), Crotalinae (subfamily), Lachesis (genus), Lachesis muta (species)
null
true
Lachesis muta
7
row_3817
false
null
997
C0HLA3
VFGGDECNINEHRSLVVLFDSDGFLCAGTLINKEWVLTAAHCDSENFQMQLGV
Snake venom serine protease LmrSP-4 (SVSP) (EC 3.4.21.-)
Lachesis muta rhombeata (Bushmaster)
60,219
53
5,845
Direct protein sequencing;Disulfide bond;Fibrinogenolytic toxin;Glycoprotein;Hemostasis impairing toxin;Hydrolase;Protease;Secreted;Serine protease;Toxin
GO:0004252; GO:0005576; GO:0006508; GO:0030141; GO:0090729
Evidence at protein level
4
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:31131000}.
null
null
PF00089;
IPR009003;IPR043504;IPR001254;IPR018114;
null
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Viperidae (family), Crotalinae (subfamily), Lachesis (genus), Lachesis muta (species)
null
true
Lachesis muta
8
row_942
false
null
1,439
P0C932
HLLQFGDLIDKIAGRSGFWYYGFYGCYCGLGGRGRPQDATDRCCFVHDCC
Acidic phospholipase A2 1 (svPLA2) (EC 3.1.1.4) (LM-PLA2-I) (Phosphatidylcholine 2-acylhydrolase)
Lachesis muta muta (Bushmaster)
8,753
50
5,642
Calcium;Direct protein sequencing;Disulfide bond;Hemostasis impairing toxin;Hydrolase;Lipid degradation;Lipid metabolism;Metal-binding;Myotoxin;Platelet aggregation inhibiting toxin;Secreted;Toxin
GO:0004623; GO:0005509; GO:0005543; GO:0005576; GO:0006644; GO:0016042; GO:0042130; GO:0047498; GO:0050482; GO:0090729
Evidence at protein level
4
SUBCELLULAR LOCATION: Secreted.
null
null
PF00068;
IPR001211;IPR016090;IPR036444;IPR033113;
null
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Viperidae (family), Crotalinae (subfamily), Lachesis (genus), Lachesis muta (species)
null
true
Lachesis muta
9
row_1378
false
null
1,440
P0C933
HLLQFEQLIRKIAGRGFRYYGFYGCYCGLGGQGRPQDATDRCCFVHDCC
Phospholipase A2 2 (svPLA2) (EC 3.1.1.4) (LM-PLA2-II) (Phosphatidylcholine 2-acylhydrolase)
Lachesis muta muta (Bushmaster)
8,753
49
5,623
Calcium;Direct protein sequencing;Disulfide bond;Hemostasis impairing toxin;Hydrolase;Lipid degradation;Lipid metabolism;Metal-binding;Myotoxin;Platelet aggregation inhibiting toxin;Secreted;Toxin
GO:0005509; GO:0005543; GO:0005576; GO:0006644; GO:0016042; GO:0042130; GO:0047498; GO:0050482; GO:0090729
Evidence at protein level
4
SUBCELLULAR LOCATION: Secreted.
null
null
PF00068;
IPR001211;IPR016090;IPR036444;IPR033113;
null
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Viperidae (family), Crotalinae (subfamily), Lachesis (genus), Lachesis muta (species)
null
true
Lachesis muta
10
row_1379
false
null
5,586
C0HLA4
DCPSGWSSYEGHCYRVFNEPKNWADAERFCKLQPKHSHLV
Snaclec LmrLEC-1
Lachesis muta rhombeata (Bushmaster)
60,219
40
4,723
Direct protein sequencing;Disulfide bond;Hemostasis impairing toxin;Secreted;Toxin
GO:0005576; GO:0090729
Evidence at protein level
2
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:31131000}.
null
null
null
IPR016186;IPR016187;
null
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Viperidae (family), Crotalinae (subfamily), Lachesis (genus), Lachesis muta (species)
null
true
Lachesis muta
11
row_5346
false
null
780
Q9PRP4
VIGGDECNINEHRFLVALYDGLSGTFLCGG
Thrombin-like enzyme LMR-47 (SVTLE LM-47) (SVTLE LMR-47) (EC 3.4.21.74) (Fibrinogen-clotting enzyme) (Gyroxin analog) (Snake venom serine protease) (SVSP) (Venombin A)
Lachesis muta rhombeata (Bushmaster)
60,219
30
3,171
Blood coagulation cascade activating toxin;Direct protein sequencing;Fibrinogenolytic toxin;Glycoprotein;Hemostasis impairing toxin;Hydrolase;Protease;Secreted;Serine protease;Toxin
GO:0005576; GO:0006508; GO:0008236; GO:0090729
Evidence at protein level
5
SUBCELLULAR LOCATION: Secreted.
null
null
null
null
null
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Viperidae (family), Crotalinae (subfamily), Lachesis (genus), Lachesis muta (species)
null
true
Lachesis muta
12
row_730
false
null
5,584
C0HLA1
VIGGDECNINEHRFLVALYDPDGFFCGGTL
Thrombin-like enzyme LmrSP-2 (SVTLE) (EC 3.4.21.-) (Snake venom serine protease) (SVSP)
Lachesis muta rhombeata (Bushmaster)
60,219
30
3,273
Blood coagulation cascade activating toxin;Direct protein sequencing;Fibrinogenolytic toxin;Hemostasis impairing toxin;Hydrolase;Protease;Secreted;Serine protease;Toxin
GO:0005576; GO:0006508; GO:0008236; GO:0090729
Evidence at protein level
2
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:31131000}.
null
null
null
IPR009003;IPR043504;
null
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Viperidae (family), Crotalinae (subfamily), Lachesis (genus), Lachesis muta (species)
null
true
Lachesis muta
13
row_5344
false
null
1,575
P0DQP2
TLLLTLVVVTIVCLDLGYTLTCVTDKSFGGVITEECAAGQKICFKNWKKMGPKLYDVKRGCTATCPKADDNGCVKCCNTDKCNK
Venom protein SynTx (Dj_SynTx) (Synergistic-like venom 3FTx protein S2C4 homolog) (T3431)
Dendroaspis jamesoni jamesoni (Jameson's mamba)
2,032,609
84
9,101
3D-structure;Direct protein sequencing;Disulfide bond;Secreted;Signal;Toxin
GO:0005576; GO:0090729
Evidence at protein level
4
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:33000863}.
SIGNAL <1..19; /evidence="ECO:0000305"
null
PF21947;
IPR003572;IPR003571;IPR045860;IPR018354;IPR054131;
7C28;
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Elapidae (family), Elapinae (subfamily), Dendroaspis (genus), Dendroaspis jamesoni (species)
null
true
Dendroaspis jamesoni
0
row_1509
false
null
3,045
P01393
RTCYKTYSDKSKTCPRGEDICYTKTWCDGFCSQRGKRVELGCAATCPKVKTGVEIKCCSTDYCNPFPVWNPR
Alpha-elapitoxin-Djk2a (Alpha-EPTX-Djk2a) (Long neurotoxin 1) (Toxin V-III-N1)
Dendroaspis jamesoni kaimosae (Eastern Jameson's mamba)
8,619
72
8,185
Acetylcholine receptor inhibiting toxin;Direct protein sequencing;Disulfide bond;Ion channel impairing toxin;Neurotoxin;Postsynaptic neurotoxin;Secreted;Toxin
GO:0005576; GO:0030550; GO:0090729; GO:0099106
Evidence at protein level
3
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:4204636}.
null
null
PF21947;
IPR003571;IPR045860;IPR018354;IPR054131;
null
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Elapidae (family), Elapinae (subfamily), Dendroaspis (genus), Dendroaspis jamesoni (species)
null
true
Dendroaspis jamesoni
1
row_2943
false
null
6,741
P25682
LECYRCGVSGCHLRTTCSAKEKFCAKQHNRISTLWWHGCVETCTEDETWKFYRKCCTTNLCNI
Toxin S6C6
Dendroaspis jamesoni kaimosae (Eastern Jameson's mamba)
8,619
63
7,398
Direct protein sequencing;Disulfide bond;Neurotoxin;Presynaptic neurotoxin;Secreted;Toxin
GO:0005576; GO:0090729
Evidence at protein level
2
SUBCELLULAR LOCATION: Secreted {ECO:0000269|Ref.1}.
null
null
PF00087;
IPR045860;IPR035076;
null
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Elapidae (family), Elapinae (subfamily), Dendroaspis (genus), Dendroaspis jamesoni (species)
null
true
Dendroaspis jamesoni
2
row_6489
false
null
6,043
P01407
LTCVTDKSFGGVNTEECAAGQKICFKNWKKMGPKLYDVKRGCTATCPKADDDGCVKCCNTDK
Synergistic-type venom protein S2C4
Dendroaspis jamesoni kaimosae (Eastern Jameson's mamba)
8,619
62
6,726
Direct protein sequencing;Disulfide bond;Secreted;Toxin
GO:0005576; GO:0090729
Evidence at protein level
2
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:437703}.
null
null
PF21947;
IPR003571;IPR045860;IPR018354;IPR054131;
null
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Elapidae (family), Elapinae (subfamily), Dendroaspis (genus), Dendroaspis jamesoni (species)
null
true
Dendroaspis jamesoni
3
row_5802
false
null
6,047
P01413
RICYNHLGTKPPTTECTQEDSCYKNIWRNITFDNIRRGCGCFTPRGDMPGPYCCESDKCNL
Toxin S5C1
Dendroaspis jamesoni kaimosae (Eastern Jameson's mamba)
8,619
61
7,024
Cell adhesion impairing toxin;Direct protein sequencing;Disulfide bond;Hemostasis impairing toxin;Platelet aggregation inhibiting toxin;Secreted;Toxin
GO:0005576; GO:0090729
Evidence at protein level
2
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:465532}.
null
null
null
IPR045860;
null
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Elapidae (family), Elapinae (subfamily), Dendroaspis (genus), Dendroaspis jamesoni (species)
null
true
Dendroaspis jamesoni
4
row_5806
false
null
3,053
P01417
RICYNHQSTTPATTKSCGENSCYKKTWSDHRGTIIERGCGCPKVKQGIHLHCCQSDKCNN
Short neurotoxin 1
Dendroaspis jamesoni kaimosae (Eastern Jameson's mamba)
8,619
60
6,729
Acetylcholine receptor inhibiting toxin;Direct protein sequencing;Disulfide bond;Ion channel impairing toxin;Neurotoxin;Postsynaptic neurotoxin;Secreted;Toxin
GO:0005576; GO:0030550; GO:0090729; GO:0099106
Evidence at protein level
3
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:4204636}.
null
null
PF21947;
IPR003571;IPR045860;IPR018354;IPR054131;
null
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Elapidae (family), Elapinae (subfamily), Dendroaspis (genus), Dendroaspis jamesoni (species)
null
true
Dendroaspis jamesoni
5
row_2951
false
null
3,939
P25683
RICYTHKSLQAKTTKSCEGNTCYKMFIRTSREYISERGCGCPTAMWPYQTECCKGDRCNK
Toxin S4C8
Dendroaspis jamesoni kaimosae (Eastern Jameson's mamba)
8,619
60
6,968
Calcium channel impairing toxin;Cardiotoxin;Direct protein sequencing;Disulfide bond;Ion channel impairing toxin;Secreted;Toxin;Voltage-gated calcium channel impairing toxin
GO:0005246; GO:0005576; GO:0090729
Evidence at protein level
3
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:7428994}.
null
null
PF21947;
IPR003571;IPR045860;IPR018354;IPR054131;
null
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Elapidae (family), Elapinae (subfamily), Dendroaspis (genus), Dendroaspis jamesoni (species)
null
true
Dendroaspis jamesoni
6
row_3784
false
null
6,042
P01406
MICYSHKTPQNSATITCEEKTCYKKFVTNVPGVILARGCGCPKKEIFRSIHCCRSDKCNE
Toxin S5C4
Dendroaspis jamesoni kaimosae (Eastern Jameson's mamba)
8,619
60
6,772
Direct protein sequencing;Disulfide bond;Secreted;Toxin
GO:0005576; GO:0090729
Evidence at protein level
2
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:669583}.
null
null
PF21947;
IPR003571;IPR045860;IPR018354;IPR054131;
null
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Elapidae (family), Elapinae (subfamily), Dendroaspis (genus), Dendroaspis jamesoni (species)
null
true
Dendroaspis jamesoni
7
row_5801
false
null
3,055
P01419
RICYNHQSNTPATTKSCVENSCYKSIWADHRGTIIKRGCGCPRVKSKIKCCKSDNCNL
Toxin S5C10
Dendroaspis jamesoni kaimosae (Eastern Jameson's mamba)
8,619
58
6,522
Acetylcholine receptor inhibiting toxin;Direct protein sequencing;Disulfide bond;Ion channel impairing toxin;Neurotoxin;Postsynaptic neurotoxin;Secreted;Toxin
GO:0005576; GO:0030550; GO:0090729; GO:0099106
Evidence at protein level
3
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:465532}.
null
null
PF21947;
IPR003571;IPR045860;IPR054131;
null
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Elapidae (family), Elapinae (subfamily), Dendroaspis (genus), Dendroaspis jamesoni (species)
null
true
Dendroaspis jamesoni
8
row_2953
false
null
2,664
C0HLA8
RPSFCNLPVKPGPCSGFFSAFYYSQKTNKCHSFTYSGCRGNGNRFRTIEECRRTCVG
Mambaquaretin-5 (MQ5) (Upsilon-Dj2a)
Dendroaspis jamesoni kaimosae (Eastern Jameson's mamba)
8,619
57
6,464
Direct protein sequencing;Disulfide bond;G-protein coupled receptor impairing toxin;Secreted;Toxin
GO:0004867; GO:0005615; GO:0090729
Evidence at protein level
3
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:35122240}.
null
null
PF00014;
IPR002223;IPR036880;IPR020901;IPR050098;
null
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Elapidae (family), Elapinae (subfamily), Dendroaspis (genus), Dendroaspis jamesoni (species)
null
true
Dendroaspis jamesoni
9
row_2574
false
null
443
P56855
TCRYLFGGCKTTADCCKHLACRSDGKYCAWDGTF
Kappa-theraphotoxin-Scg1a (Kappa-TRTX-Scg1a) (SGTx1) (SGTx) (SgTx-I)
Stromatopelma calceatum griseipes (Feather leg baboon tarantula) (Scodra griseipes)
118,974
34
3,782
3D-structure;Direct protein sequencing;Disulfide bond;Ion channel impairing toxin;Knottin;Neurotoxin;Potassium channel impairing toxin;Secreted;Toxin;Voltage-gated potassium channel impairing toxin
GO:0005615; GO:0008200; GO:0015459; GO:0090729
Evidence at protein level
5
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:10504388}.
null
null
PF07740;
IPR011696;
1LA4;
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Protostomia (clade), Ecdysozoa (clade), Panarthropoda (clade), Arthropoda (phylum), Chelicerata (subphylum), Arachnida (class), Araneae (order), Mygalomorphae (suborder), Theraphosidae (family), Stromatopelma (genus), Stromatopelma calceatum (species)
null
true
Stromatopelma calceatum
0
row_407
false
null
2,443
A2CJE2
NPCCDAATCKLKSGSQCGHGDCCEQCKFSKSGTECRASMSECDPAEHCTGQSSECPADVFHKNGQPCLDNYGYCYNGNCPIMYHQCYDLFGADVYEAEDSCFERNQKGNYYGYCRKENGNKIPCAPEDVKCGRLYCKDNSPGQNNPCKMFYSNEDEHKGMVLPGTKCADGKVCSNRQ
Zinc metalloproteinase-disintegrin-like scutiarin (EC 3.4.24.-) (Snake venom metalloproteinase) (SVMP)
Crotalus scutulatus scutulatus (Mojave rattlesnake)
8,738
177
19,578
Calcium;Disulfide bond;Glycoprotein;Hemostasis impairing toxin;Hydrolase;Metal-binding;Metalloprotease;Protease;Secreted;Toxin;Zinc
GO:0005576; GO:0005886; GO:0006508; GO:0008237; GO:0046872; GO:0090729
Evidence at transcript level
3
SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
null
null
PF08516;PF00200;
IPR006586;IPR018358;IPR001762;IPR036436;
null
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Viperidae (family), Crotalinae (subfamily), Crotalus (genus), Crotalus scutulatus (species)
null
true
Crotalus scutulatus
0
row_2356
false
null
479
P62023
MRALWIVAVLLVGVEGHLLQFNKMIKFETRKNAIPFYAFYGCYCGWGGRGRPKDATDRCCFVHDCCYGKLAKCNTKWDIYPYSLKSGYITCGKGTWCEEQICECDRVAAECLRRSLSTYKYGYMFYPDSRCRGPSETC
Basic phospholipase A2 Mtx-b (svPLA2) (EC 3.1.1.4) (Mojave toxin basic chain) (Phosphatidylcholine 2-acylhydrolase) (Phospholipase A2 CB1)
Crotalus scutulatus scutulatus (Mojave rattlesnake)
8,738
138
15,907
Calcium;Direct protein sequencing;Disulfide bond;Hydrolase;Lipid degradation;Lipid metabolism;Metal-binding;Neurotoxin;Presynaptic neurotoxin;Secreted;Signal;Toxin
GO:0005509; GO:0005543; GO:0005576; GO:0006644; GO:0016042; GO:0042130; GO:0047498; GO:0050482; GO:0090729
Evidence at protein level
5
SUBCELLULAR LOCATION: Secreted.
SIGNAL 1..16; /evidence="ECO:0000269|PubMed:15032748, ECO:0000269|PubMed:2402763"
null
PF00068;
IPR001211;IPR033112;IPR016090;IPR036444;IPR033113;
null
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Viperidae (family), Crotalinae (subfamily), Crotalus (genus), Crotalus scutulatus (species)
null
true
Crotalus scutulatus
1
row_443
false
null
1,661
P18998
MRALWIVAVLLVGVEGSLVEFETLIMKIAGRSGISYYSSYGCYCGAGGQGWPQDASDRCCFEHDCCYAKLTGCDPTTDVYTYRQEDGEIVCGGDDPCGTQICECDKAAAICFRDSMNTYDYKYLRFSPENCQGESQPC
Phospholipase A2 homolog mojave toxin acidic chain (Mtx-a) [Cleaved into: Mojave toxin acidic chain A; Mojave toxin acidic chain B; Mojave toxin acidic chain C]
Crotalus scutulatus scutulatus (Mojave rattlesnake)
8,738
138
15,211
Direct protein sequencing;Disulfide bond;Neurotoxin;Presynaptic neurotoxin;Pyrrolidone carboxylic acid;Secreted;Signal;Toxin
GO:0005509; GO:0005543; GO:0005576; GO:0006644; GO:0016042; GO:0042130; GO:0047498; GO:0050482; GO:0090729
Evidence at protein level
4
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:2310754}.
SIGNAL 1..40; /evidence="ECO:0000305|PubMed:2310754"
null
PF00068;
IPR001211;IPR033112;IPR016090;IPR036444;IPR033113;
null
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Viperidae (family), Crotalinae (subfamily), Crotalus (genus), Crotalus scutulatus (species)
null
true
Crotalus scutulatus
2
row_1590
false
null
1,425
P0C7X7
EAGEECDCGSPANPCCDAATCKLRPGAQCADGLCCDQCRFIKKGTVCRPARGDWNDDTCTGQSADCPRNGLYG
Disintegrin mojastin-2 [Cleaved into: Disintegrin mojastin-1]
Crotalus scutulatus scutulatus (Mojave rattlesnake)
8,738
73
7,650
Cell adhesion impairing toxin;Direct protein sequencing;Disulfide bond;Hemostasis impairing toxin;Platelet aggregation inhibiting toxin;Secreted;Toxin
GO:0005576; GO:0090729
Evidence at protein level
4
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:16084550, ECO:0000269|PubMed:20598348}.
null
null
PF00200;
IPR018358;IPR001762;IPR036436;
null
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Viperidae (family), Crotalinae (subfamily), Crotalus (genus), Crotalus scutulatus (species)
null
true
Crotalus scutulatus
3
row_1364
false
null
493
P75409
MPNPVRFVYRVDLRSPEEIFEHGFSTLGDVRNFFEHILSTNFGRSYFISTSETPTAAIRFFGSWLREYVPEHPRRAYLYEIRADQHFYNARATGENLLDLMRQRQVVFDSGDREMAQMGIRALRTSFAYQREWFTDGPIAAANVRSAWLVDAVPVEPGHAHHPAGRVVETTRINEPEMHNPHYQELQTQANDQPWLPTPGIATPVHLSIPQAASVADVSEGTSASLSFACPDWSPPSSNGENPLDKCIAEKIDNYNLQSLPQYASSVKELEDTPVYLRGIKTQKTFMLQADPQNNNVFLVEVNPKQKSSFPQTIFFWDVYQRICLKDLTGAQISLSLTAFTTQYAGQLKVHLSVSAVNAVNQKWKMTPQDIAITQFRVSSELLGQTENGLFWNTKSGGSQHDLYVCPLKNPPSDLEELQIIVDECTTHAQFVTMRAASTFFVDVQLGWYWRGYYYTPQLSGWSYQMKTPDGQIFYDLKTSKIFFVQDNQNVFFLHNKLNKQTGYSWDWVEWLKHDMNEDKDENFKWYFSRDDLTIPSVEGLNFRHIRCYADNQQLKVIISGSRWGGWYSTYDKVESNVEDKILVKDGFDRF
ADP-ribosylating toxin CARDS (EC 2.4.2.-) (ADP-ribosyltransferase CARDS) (Community-Acquired Respiratory Distress Syndrome Toxin) (CARDX TX)
Mycoplasma pneumoniae (strain ATCC 29342 / M129 / Subtype 1) (Mycoplasmoides pneumoniae)
272,634
591
68,057
3D-structure;Cell membrane;Cell projection;Cytoplasm;Disulfide bond;Glycosyltransferase;Host cytoplasm;Host endoplasmic reticulum;Lipid-binding;Membrane;NAD;Nucleotidyltransferase;Reference proteome;Toxin;Transferase;Virulence
GO:0003950; GO:0005576; GO:0005737; GO:0005886; GO:0008289; GO:0009986; GO:0016779; GO:0033099; GO:0042995; GO:0044075; GO:0044164; GO:0044165; GO:0090729; GO:0141079
Evidence at protein level
5
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:16617115, ECO:0000269|PubMed:20199607}. Cytoplasm {ECO:0000269|PubMed:16617115, ECO:0000269|PubMed:20199607}. Cell surface {ECO:0000269|PubMed:15845487, ECO:0000269|PubMed:20199607}. Cell projection, attachment organelle {ECO:0000269|PubMed:20199607}. Host cytoplasm, host cytosol {ECO:0000269|PubMed:25538194}. Host endoplasmic reticulum {ECO:0000269|PubMed:29362229, ECO:0000269|PubMed:34078958}. Note=In bacteria most protein is cytoplasmic, 7-10% is on cell surface, including in the tip (attachment) organelle (PubMed:20199607). In host cells is found in the cytosol and in a punctate pattern in the perinuclear region in the host ER (PubMed:25538194, PubMed:29362229, PubMed:34078958). In host cells, an isolated C-terminal fragment (residues 273-591) is detected in a larger punctate pattern (PubMed:34078958). In 10% of host cells colocalizes with the speck NLRP3 inflammasome complex (purified protein incubated with mouse macrophages) (PubMed:25538194). {ECO:0000269|PubMed:20199607, ECO:0000269|PubMed:25538194, ECO:0000269|PubMed:29362229, ECO:0000269|PubMed:34078958}.
null
null
PF22509;PF22346;PF02917;
IPR003898;IPR055043;IPR055042;
4TLV;4TLW;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Mycoplasmatota (phylum), Mycoplasmoidales (order), Mycoplasmoidaceae (family), Mycoplasmoides (genus), Mycoplasmoides pneumoniae (species)
cards MPN_372 MP464
true
Mycoplasmoides pneumoniae
0
row_457
false
null
1,971
Q10754
MRTLWIVAVCLIGVEGNLFQFGDMILQKTGKEAVHSYAIYGCYCGWGGQGRAQDATDRCCFAQDCCYGRVNDCNPKMATYTYSFENGDIVCGDNDLCLRAVCECDRAAAICLGENVNTYDKNYEYYSISHCTEESEQC
Acidic phospholipase A2 inhibitor vaspin A chain (VaspA) (svPLA2 homolog) (PLA2-I complex chain A)
Vipera aspis zinnikeri (Viper)
55,427
138
15,411
Direct protein sequencing;Disulfide bond;Neurotoxin;Phospholipase A2 inhibitor;Postsynaptic neurotoxin;Secreted;Signal;Toxin
GO:0005509; GO:0005543; GO:0005576; GO:0006644; GO:0016042; GO:0019834; GO:0042130; GO:0047498; GO:0050482; GO:0090729
Evidence at protein level
4
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:8619619}.
SIGNAL 1..16; /evidence="ECO:0000255"
null
PF00068;
IPR001211;IPR033112;IPR016090;IPR036444;
null
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Viperidae (family), Viperinae (subfamily), Vipera (genus), Vipera aspis (species)
null
true
Vipera aspis
0
row_1890
false
null
2,168
Q8JFG0
MRILWIVAVCLIGVEGNLFQFAKMINGKLGAFSVWNYISYGCYCGWGGQGTPKDATDRCCFVHDCCYGRVRGCNPKLAIYSYSFKKGNIVCGKNNGCLRDICECDRVAANCFHQNKNTYNKNYRFLSSSRCRQTSEQC
Basic phospholipase A2 vaspin B chain (svPLA2) (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase) (Vaspin toxic component)
Vipera aspis aspis (Aspic viper)
194,601
138
15,610
Calcium;Disulfide bond;Hydrolase;Lipid degradation;Lipid metabolism;Metal-binding;Neurotoxin;Postsynaptic neurotoxin;Presynaptic neurotoxin;Secreted;Signal;Toxin
GO:0005509; GO:0005543; GO:0005576; GO:0006644; GO:0016042; GO:0042130; GO:0047498; GO:0050482; GO:0090729
Evidence at transcript level
4
SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
SIGNAL 1..16; /evidence="ECO:0000250"
null
PF00068;
IPR001211;IPR033112;IPR016090;IPR036444;IPR033113;
null
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Viperidae (family), Viperinae (subfamily), Vipera (genus), Vipera aspis (species)
null
true
Vipera aspis
1
row_2084
false
null
536
P83942
QVRPFLEVHERSACQARETLVSILQEYPDEISDIFRPSCVAVLRCSGCCTDESLKCTPVGKHTVDLQIMRVNPRTQSSKMEVMKFTEHTACECRPRRKQGEPDGPKEKPR
Snake venom vascular endothelial growth factor toxin HF (svVEGF) (Heparin-binding dimeric hypotensive factor) (Hypotensive factor) (HF) (VEGF-F)
Vipera aspis aspis (Aspic viper)
194,601
110
12,561
Direct protein sequencing;Disulfide bond;Growth factor;Pyrrolidone carboxylic acid;Secreted;Toxin
GO:0001666; GO:0001938; GO:0002040; GO:0005172; GO:0005615; GO:0008083; GO:0016020; GO:0038084; GO:0042056; GO:0045766; GO:0048010; GO:0050930; GO:0060754; GO:0090729
Evidence at protein level
5
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:10512636, ECO:0000269|PubMed:14600159}.
null
null
PF00341;
IPR029034;IPR023581;IPR000072;IPR050507;
null
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Viperidae (family), Viperinae (subfamily), Vipera (genus), Vipera aspis (species)
null
true
Vipera aspis
2
row_500
false
null
4,699
Q7LZ24
AFCCPSGWSAYDQ
Snaclec coagulation factor X-activating enzyme light chain 2 (Factor X activator LC2)
Vipera aspis aspis (Aspic viper)
194,601
13
1,435
Blood coagulation cascade activating toxin;Calcium;Direct protein sequencing;Disulfide bond;Glycoprotein;Hemostasis impairing toxin;Lectin;Metal-binding;Secreted;Toxin
GO:0005576; GO:0030246; GO:0046872; GO:0090729
Evidence at protein level
3
SUBCELLULAR LOCATION: Secreted.
null
null
null
null
null
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Viperidae (family), Viperinae (subfamily), Vipera (genus), Vipera aspis (species)
null
true
Vipera aspis
3
row_4475
false
null
580
Q04IN8
MANKAVNDFILAMNYDKKKLLTHQGESIENRFIKEGNQLPDEFVVIERKKRSLSTNTSDISVTATNDSRLYPGALLVVDETLLENNPTLLAVDRAPMTYSIDLPGLASSDSFLQVEDPSNSSVRGAVNDLLAKWHQDYGQVNNVPARMQYEKITAHSMEQLKVKFGSDFEKTGNSLDIDFNSVHSGEKQIQIVNFKQIYYTVSVDAVKNPGDVFQDTVTVEDLKQRGISAERPLVYISSVAYGRQVYLKLETTSKSDEVEAAFEALIKGVKVAPQTEWKQILDNTEVKAVILGGDPSSGARVVTGKVDMVEDLIQEGSRFTADHPGLPISYTTSFLRDNVVATFQNSTDYVETKVTAYRNGDLLLDHSGAYVAQYYITWDELSYDHQGKEVLTPKAWDRNGQDLTAHFTTSIPLKGNVRNLSVKIRECTGLAWEWWRTVYEKTDLPLVRKRTISIWGTTLYPQVEDKVEND
Pneumolysin (PLY) (Thiol-activated cytolysin)
Streptococcus pneumoniae serotype 2 (strain D39 / NCTC 7466)
373,153
471
52,899
3D-structure;Cytolysis;Direct protein sequencing;Hemolysis;Host cell membrane;Host membrane;Lipid-binding;Membrane;Reference proteome;Secreted;Toxin;Transmembrane;Transmembrane beta strand;Virulence
GO:0005576; GO:0015485; GO:0016020; GO:0020002; GO:0031640; GO:0090729
Evidence at protein level
5
SUBCELLULAR LOCATION: Secreted {ECO:0000250|UniProtKB:P0C2J9}. Host cell membrane {ECO:0000269|PubMed:28323617, ECO:0000305|PubMed:15851031}; Multi-pass membrane protein {ECO:0000269|PubMed:28323617}. Note=Secreted as soluble protein by the accessory Sec system (By similarity). It then inserts into the host cell membrane and forms pores formed by transmembrane beta-strands (PubMed:15851031, PubMed:28323617). {ECO:0000250|UniProtKB:P0C2J9, ECO:0000269|PubMed:15851031, ECO:0000269|PubMed:28323617}.
null
TRANSMEM 158..171; /note="Beta stranded"; /evidence="ECO:0000269|PubMed:28323617, ECO:0007744|PDB:5LY6"; TRANSMEM 178..187; /note="Beta stranded"; /evidence="ECO:0000269|PubMed:28323617, ECO:0007744|PDB:5LY6"; TRANSMEM 256..265; /note="Beta stranded"; /evidence="ECO:0000269|PubMed:28323617, ECO:0007744|PDB:5LY6"; TRANSMEM 273..285; /note="Beta stranded"; /evidence="ECO:0000269|PubMed:28323617, ECO:0007744|PDB:5LY6"
PF17440;PF01289;
IPR035390;IPR038700;IPR001869;IPR036363;IPR036359;
4ZGH;5AOD;5AOE;5AOF;5CR6;5CR8;5LY6;7T2A;7T2B;7T2C;7T2D;
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Bacillota (phylum), Bacilli (class), Lactobacillales (order), Streptococcaceae (family), Streptococcus (genus), Streptococcus pneumoniae (species)
ply SPD_1726
true
Streptococcus pneumoniae
0
row_543
false
null
584
Q07730
MKFSKIACATVFALSSQAAIIHHAPEFNMKRDVAPAAPAAPADQAPTVPAPQEFNTAITKRSIIGIIMGILGNIPQVIQIIMSIVKAFKGNKREDIDSVVAGIIADMPFVVRAVDTAMTSVASTKRDGANDDVANAVVRLPEIVARVATGVQQSIENAKRDGVPDVGLNLVANAPRLISNVFDGVSETVQQAKRDGLEDFLDELLQRLPQLITRSAESALKDSQPVKRDAGSVALSNLIKKSIETVGIENAAQIVSERDISSLIEEYFGKA
Extent of cell elongation protein 1 [Cleaved into: ECE1-I; ECE1-II; Candidalysin ECE1-III; ECE1-IV; ECE1-V; ECE1-VI; ECE1-VII; ECE1-VIII]
Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
237,561
271
28,878
Cleavage on pair of basic residues;Host cell membrane;Host membrane;Membrane;Reference proteome;Repeat;Secreted;Signal;Toxin;Transmembrane;Transmembrane helix;Virulence
GO:0001897; GO:0005539; GO:0005576; GO:0009609; GO:0016020; GO:0020002; GO:0030446; GO:0044179; GO:0052553; GO:0090729; GO:0140912; GO:0141139
Evidence at protein level
5
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:23136884}.; SUBCELLULAR LOCATION: [Candidalysin ECE1-III]: Host cell membrane {ECO:0000269|PubMed:27027296}; Single-pass membrane protein {ECO:0000255}. Note=Candidalysin is delivered to the invasion pocket in which the hypha is tightly surrounded by the host membrane, to enable the full damage potential of during mucosal infection. {ECO:0000269|PubMed:34245079}.
SIGNAL 1..18; /evidence="ECO:0000255"
TRANSMEM 62..82; /note="Helical"; /evidence="ECO:0000255"
null
null
null
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Fungi (kingdom), Dikarya (subkingdom), Ascomycota (phylum), saccharomyceta (clade), Saccharomycotina (subphylum), Pichiomycetes (class), Serinales (order), Debaryomycetaceae (family), Candida/Lodderomyces clade (clade), Candida (genus), Candida albicans (species)
ECE1 CAALFM_C403470CA CaO19.10882 CaO19.3374
true
Candida albicans
0
row_547
false
null
602
Q1ID47
MSKVKESAIVSATSALQPQGPSSSYGLINSFAHQYDRGGANVNGKPSYTVDQAANYLLRDGAAWKDLNKDGTISLSYTFLTKAPSDFYSRGLGTFSQFSDLQKGQAKLAMQSWADVAKVTFTEAASGGDGHMTFGNFSASNGGAAFAYLPFDMPGSHKGESWYLINSSYQVNTTPGTGNYGRQTLTHEIGHVLGLSHPGDYNAGEGNPTYRDATYAQDTRGYSVMSYWSESNTGQNFVKAGGQYYASAPLMDDIAAIQKLYGANYATRSGDTVYGFNSNADRDFYSATSSSSKLVFSVWDGGGNDTFDFSGFTQNQKINLNETSFSDVGGMIGNVSIAKGVTIENAFGGSGNDLLIGNALANVLKGGAGNDIIYGGGGADQLWGGTGADTFVFGAISDSTKAAPDRIMDFTSGQDKIDLSAISAFAVNKLPLQFVNAFTGHAGEAVLSYDQGTNLGSLSIDFTGNSSADFLVTTVGQAAVTDIVV
Metalloprotease AprA (EC 3.4.24.-)
Pseudomonas entomophila (strain L48)
384,676
485
50,931
Calcium;Hydrolase;Metal-binding;Metalloprotease;Protease;Repeat;Secreted;Toxin;Virulence;Zinc
GO:0004222; GO:0005509; GO:0005615; GO:0008233; GO:0008270; GO:0030198; GO:0030574; GO:0031638; GO:0090729
Evidence at protein level
5
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:16789834, ECO:0000269|PubMed:21980286}. Note=Is probably secreted via the associated Type 1 transporter encoded by aprDEF. {ECO:0000305|PubMed:16789834}.
null
null
PF00353;PF08548;PF13583;
IPR018511;IPR001343;IPR024079;IPR016294;IPR013858;IPR006026;IPR034033;IPR011049;
null
cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Gammaproteobacteria (class), Pseudomonadales (order), Pseudomonadaceae (family), Pseudomonas (genus), Pseudomonas entomophila (species)
aprA PSEEN1550
true
Pseudomonas entomophila
0
row_563
false
null
601
Q1I8U1
MTIKEELGQPQSHSIELDEVSKEAASTRAALTSNLSGRFDQYPTKKGDFAIDGYLLDYSSPKQGCWVDGITVYGDIYIGKQNWGTYTRPVFAYLQYVETISIPQNVTTTLSYQLTKGHTRSFETSVNAKYSVGANIDIVNVGSEISTGFTRSESWSTTQSFTDTTEMKGPGTFVIYQVVLVYAHNATSAGRQNANAFAYSKTQAVGSRVDLYYLSAITQRKRVIVPSSNAVTPLDWDTVQRNVLMENYNPGSNSGHFSFDWSAYNDPHRRY
Monalysin (beta-barrel pore-forming toxin) (beta-PFT)
Pseudomonas entomophila (strain L48)
384,676
271
30,201
3D-structure;Cytolysis;Direct protein sequencing;Hemolysis;Host cell membrane;Host membrane;Ion transport;Membrane;Porin;Secreted;Toxin;Transmembrane;Transmembrane beta strand;Transport;Virulence;Zymogen
GO:0005576; GO:0006811; GO:0015288; GO:0020002; GO:0044179; GO:0046930; GO:0051260; GO:0090729
Evidence at protein level
5
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:21980286}. Host cell membrane {ECO:0000305|PubMed:21980286}.
null
null
PF18063;
IPR040927;
4MJT;4MKO;4MKQ;
cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Gammaproteobacteria (class), Pseudomonadales (order), Pseudomonadaceae (family), Pseudomonas (genus), Pseudomonas entomophila (species)
mnl PSEEN3174
true
Pseudomonas entomophila
1
row_562
false
null
665
Q63KH5
MLEHGVMKIPGINNVGKTGQAGGETERIPSTEPLGSSAATSPAGPLGGLPARSSSISNTNRTGENPMITPIISSNLGLKHRVTLRKATLASLMQSLSGESSNRVMWNDRYDTLLIARDPREIKNAIEKSVTDFGGLENYKELTGGADPFALMTPVCGLSANNIFKLMTEKDVPIDPTSIEYLENTSFAEHVNTLDSHKNYVVIVNDGRLGHKFLIDLPALTQGPRTAYIIQSDLGGGALPAVRVEDWISRRGSDPVSLDELNQLLSKDFSKMPDDVQTRLLASILQIDKDPHKVDIKKLHLDGKLRFASHEYDFRQFQRNAQYVAGLG
Protein-glutamine deamidase Cif (EC 3.5.1.44) (Cycle-inhibiting factor homolog) (CHBP)
Burkholderia pseudomallei (strain K96243)
272,560
328
35,819
3D-structure;Host nucleus;Hydrolase;Reference proteome;Secreted;Toxin;Virulence
GO:0005576; GO:0042025; GO:0044071; GO:0050568; GO:0085034; GO:0090729
Evidence at protein level
5
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:19308257, ECO:0000269|PubMed:20688984}. Host nucleus {ECO:0000250|UniProtKB:P0DUW5}. Note=Secreted via the type III secretion system (T3SS). {ECO:0000269|PubMed:19308257, ECO:0000269|PubMed:20688984}.
null
null
PF16374;
IPR032278;
3EIR;3EIT;3GQM;4HCN;4HCP;
cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Betaproteobacteria (class), Burkholderiales (order), Burkholderiaceae (family), Burkholderia (genus), pseudomallei group (no rank), Burkholderia pseudomallei (species)
cif BPSS1385
true
Burkholderia pseudomallei
0
row_620
false
null
679
Q6RY98
IWDEPVVVSARDTEEAARVPSPQKRSQPLCSCNDINDKECMYFCHQDVIWDEPVVVSVRDTEEAARVPSPQKRPQPRCSCNDMNDKECMYFCHQDVIWDEPVVVSVRDTEEAARVPSPQKRSQPRCSCNDMNDKECVYFCHLDIIWDEPVVVSVRDTEEATRVPSPQKRSQPLCSCNDINDKECMYFCHQDIIWDEPVVVSVRDTEEAARVPSPQKRSQPLCSCNDINDKECMYFCHQDIIWDEPVVVSVRDTEEAARVPSPQKRSQPLCSCNDINDKECMYFCHQDVIWDEPVVVSVQDTEEAARVPSPQKRSQPLCSCNNMSDKECLNFCNLDIIWENVDTSADPEFLG
Long-sarafotoxin (L-SRTX) [Cleaved into: Sarafotoxin-m (SRTX-m); Sarafotoxin-m1 (SRTX-m1); Sarafotoxin-m2 (SRTX-m2); Sarafotoxin-m3 (SRTX-m3); Sarafotoxin-m4 (SRTX-m4); Sarafotoxin-m5 (SRTX-m5)]
Atractaspis microlepidota microlepidota
172,021
351
40,341
3D-structure;Cardiotoxin;Direct protein sequencing;Disulfide bond;G-protein coupled receptor impairing toxin;Repeat;Secreted;Toxin;Vasoactive;Vasoconstrictor
GO:0003100; GO:0005179; GO:0005615; GO:0006874; GO:0014826; GO:0019229; GO:0031708; GO:0090729
Evidence at protein level
5
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:15350691}.
null
null
PF00322;
IPR020475;IPR019764;IPR001928;
2LDF;
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Lamprophiidae (family), Atractaspidinae (subfamily), Atractaspis (genus), Atractaspis microlepidota (species)
null
true
Atractaspis microlepidota
0
row_634
false
null
1,207
C9E1R8
MIQVLLVTICLAAFPYQGSSIILESGNVNDYEIVYPRKVTALPKGAVQPKYEDAMQYELKVSGEPVVLHLEKNKQLFSKDYSETHYSPDGREITTYPLVEDHCYYHGRIENDADSTASISACNGLKGHFKLQGEMYLIEPLKLPDSEAHAVYKYENVEKEDEALKMCGVTQNWESYEPIKKASQLVVTAEHQKYNPFRFVELFLVVDKAMVTKNNGDLDKIKTRMYEIVNTVNEIYRYMYIHVALVGLEIWSNEDKITVKPEAGYTLNAFGEWRKTDLLTRKKHDNAQLLTAIDLDRVIGLAYVGSMCHPKRSTGIIQDYSEINLVVAVIMAHEMGHNLGINHDSGYCSCGDYACIMRPEISPEPSTFFSNCSYFECWDFIMNHNPECILNEPLGTDIISPPVCGNELLEVGEECDCGTPENCQNECCDAATCKLKSGSQCGHGDCCEQCKFSKSGTECRASMSECDPAEHCTGQSSECPADVFHKNGQPCLDNYGYCYNGNCPIMYHQCYDLFGADVYEAEDSCFERNQKGNYYGYCRKENGNKIPCAPEDVKCGRLYCKDNSPGQNNPCKMFYSNEDEHKGMVLPGTKCADGKVCSNGHCVDVATAY
Zinc metalloproteinase-disintegrin-like VMP-III (CvvVMP-III) (EC 3.4.24.-) (Snake venom metalloproteinase) (SVMP)
Crotalus viridis viridis (Prairie rattlesnake)
8,742
609
68,364
Calcium;Cell adhesion impairing toxin;Disulfide bond;Glycoprotein;Hemostasis impairing toxin;Hydrolase;Metal-binding;Metalloprotease;Protease;Secreted;Signal;Toxin;Zinc;Zymogen
GO:0004222; GO:0005576; GO:0005886; GO:0006508; GO:0046872; GO:0090729
Evidence at transcript level
4
SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
SIGNAL 1..20; /evidence="ECO:0000255"
null
PF08516;PF00200;PF01562;PF01421;
IPR006586;IPR018358;IPR001762;IPR036436;IPR024079;IPR001590;IPR002870;IPR034027;
null
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Viperidae (family), Crotalinae (subfamily), Crotalus (genus), Crotalus viridis (species)
null
true
Crotalus viridis
0
row_1151
false
null
1,208
C9E1R9
MIQVLLVTICLAVFPYQGSSIILESGNVNDYEVVYPRKVTALPKGAVQPKYEDAMQYEFKVNGEPVVLHLEKNKGLFSEDYSETHYSPDGREITTYPLVEDHCYYHGRIENDADSTASISACNGLKGHFKLQGELYLIEPLKFPDSEAHAVFKYENVEKEDNAPKMCGVTQNWKSYEPIKKASQLNLTPEQQRFPQRYIELVIVADHRMFTKYNSNLNTIRIWVHEIVNTINVFYRSLHIVVSLTDLEIWSNQDQINVQSAAADTLEAFGEWRETVLLNRISHDNAQLLTAINFQGNIIGRAYTGSMCDPRKSVGIITDHSAINLWVAVTMAHELAHNLGISHDGNQCHCDANSCIMSEELSEELSFEFSDCSLNQYQTYLTDHNPQCMLNEPLGTDTVSRNELLEAGEECDCGSPANPCCDAATCKLRPGAQCAEGLCCDQCRFIKKGKICRRARGDNPDDRCTGQSADCPRNRFHA
Zinc metalloproteinase/disintegrin VMP-II [Cleaved into: Snake venom metalloproteinase (SVMP) (EC 3.4.24.-); Disintegrin viridistatin-2 (Disintegrin beta subunit)]
Crotalus viridis viridis (Prairie rattlesnake)
8,742
478
53,814
Calcium;Cell adhesion impairing toxin;Disulfide bond;Hemostasis impairing toxin;Hydrolase;Metal-binding;Metalloprotease;Platelet aggregation inhibiting toxin;Protease;Secreted;Signal;Toxin;Zinc;Zymogen
GO:0004222; GO:0005576; GO:0005886; GO:0006508; GO:0046872; GO:0090729
Evidence at transcript level
4
SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
SIGNAL 1..20; /evidence="ECO:0000255"
null
PF00200;PF01562;PF01421;
IPR018358;IPR001762;IPR036436;IPR024079;IPR001590;IPR002870;IPR034027;
null
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Viperidae (family), Crotalinae (subfamily), Crotalus (genus), Crotalus viridis (species)
null
true
Crotalus viridis
1
row_1152
false
null
2,444
A2CJE3
NPCCDAATCKLKSGSQCGHGDCCEQCKFSKSGTECRASMSECDPAEHCTGQSSECPADVFHKNGQPCLDNYGYCYNGNCPIMYHQCYDLFGADVYEAEDSCFERNQKGNYYGYCRKENGNKIPCAPEDVKCGRLYCKDNSPGQNNPCKMFYSNEDEHKGMVLPGTKCADGKVCSNRQ
Zinc metalloproteinase-disintegrin-like viristiarin (EC 3.4.24.-) (Snake venom metalloproteinase) (SVMP)
Crotalus viridis viridis (Prairie rattlesnake)
8,742
177
19,578
Calcium;Disulfide bond;Glycoprotein;Hemostasis impairing toxin;Hydrolase;Metal-binding;Metalloprotease;Protease;Secreted;Toxin;Zinc
GO:0005576; GO:0005886; GO:0006508; GO:0008237; GO:0046872; GO:0090729
Evidence at transcript level
3
SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
null
null
PF08516;PF00200;
IPR006586;IPR018358;IPR001762;IPR036436;
null
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Viperidae (family), Crotalinae (subfamily), Crotalus (genus), Crotalus viridis (species)
null
true
Crotalus viridis
2
row_2357
false
null
688
Q71QE8
MRTFWIVALLLVGVEGNLLQFNKMIKMMTKKNAFPFYTSYGCYCGWGGRGRPKDATDRCCFVHDCCYEKLTNCSPKTDIYSYSWKRGVIICGKGTPCEKQICECDRAAAVCFRENLPTYKKRYMFYLDFLCTDPSEKC
Basic phospholipase A2 Cvv-N6 (svPLA2) (EC 3.1.1.4) (Cvv myotoxin) (Phosphatidylcholine 2-acylhydrolase)
Crotalus viridis viridis (Prairie rattlesnake)
8,742
138
16,000
Calcium;Direct protein sequencing;Disulfide bond;Hydrolase;Lipid degradation;Lipid metabolism;Metal-binding;Myotoxin;Secreted;Signal;Toxin
GO:0005509; GO:0005543; GO:0005576; GO:0006644; GO:0016042; GO:0042130; GO:0047498; GO:0050482; GO:0090729
Evidence at protein level
5
SUBCELLULAR LOCATION: Secreted.
SIGNAL 1..16; /evidence="ECO:0000269|PubMed:12623078, ECO:0000269|PubMed:15032748, ECO:0000269|PubMed:9028014"
null
PF00068;
IPR001211;IPR033112;IPR016090;IPR036444;IPR033113;
null
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Viperidae (family), Crotalinae (subfamily), Crotalus (genus), Crotalus viridis (species)
null
true
Crotalus viridis
3
row_643
false
null
708
Q7ZTA6
MRTLWILAVLLLGVEGNLVQFELLIMKVAKRSGLLSYSAYGCYCGWGGYGRPQDATDRCCFVHDCCYGKVTDCNPKTASYTYSEENGEIVCGGDDPCKKQVCECDRVAAICFRDNIPSYDNKYIQFPAKNCQEKPEPC
Acidic phospholipase A2 Cvv-E6b (svPLA2) (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase)
Crotalus viridis viridis (Prairie rattlesnake)
8,742
138
15,440
Calcium;Direct protein sequencing;Disulfide bond;Hemostasis impairing toxin;Hydrolase;Lipid degradation;Lipid metabolism;Metal-binding;Platelet aggregation inhibiting toxin;Secreted;Signal;Toxin
GO:0005509; GO:0005543; GO:0005576; GO:0006644; GO:0016042; GO:0042130; GO:0047498; GO:0050482; GO:0090729
Evidence at protein level
5
SUBCELLULAR LOCATION: Secreted.
SIGNAL 1..16; /evidence="ECO:0000269|PubMed:12623078"
null
PF00068;
IPR001211;IPR033112;IPR016090;IPR036444;IPR033113;
null
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Viperidae (family), Crotalinae (subfamily), Crotalus (genus), Crotalus viridis (species)
null
true
Crotalus viridis
4
row_662
false
null
712
Q800C4
MRTLWIVAVLLLGVEGSLVQFETLIMKIAGRSGLLWYSAYGCYCGWGGHGLPQDATDRCCFVHDCCYGKATDCNPKTVSYTYSEENGEIVCGGDNPCGTQICECDKAAAICFRDNIPSYSNKYWLFLPKNCRGDPEPC
Acidic phospholipase A2 Cvv-E6a (svPLA2) (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase)
Crotalus viridis viridis (Prairie rattlesnake)
8,742
138
15,233
Calcium;Direct protein sequencing;Disulfide bond;Hemostasis impairing toxin;Hydrolase;Lipid degradation;Lipid metabolism;Metal-binding;Platelet aggregation inhibiting toxin;Secreted;Signal;Toxin
GO:0005509; GO:0005543; GO:0005576; GO:0006644; GO:0016042; GO:0042130; GO:0047498; GO:0050482; GO:0090729
Evidence at protein level
5
SUBCELLULAR LOCATION: Secreted.
SIGNAL 1..16; /evidence="ECO:0000269|PubMed:12623078"
null
PF00068;
IPR001211;IPR033112;IPR016090;IPR036444;IPR033113;
null
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Viperidae (family), Crotalinae (subfamily), Crotalus (genus), Crotalus viridis (species)
null
true
Crotalus viridis
5
row_666
false
null
2,145
Q800C3
MRTLWIVAVLLLGVEGSLVQFEMMIIKVAKRSGLFWYGAYGCYCGWGGQGRPQDATDRCCFVHDCCYGKATDCNPKTVSYTYSVKNGEIICEDDDPCKKQVCECDRVAAVCFRDNIPSYNNNYKRFPAENCREEPEPC
Acidic phospholipase A2 Cvv-E6f (svPLA2) (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase)
Crotalus viridis viridis (Prairie rattlesnake)
8,742
138
15,642
Calcium;Direct protein sequencing;Disulfide bond;Hemostasis impairing toxin;Hydrolase;Lipid degradation;Lipid metabolism;Metal-binding;Platelet aggregation inhibiting toxin;Secreted;Signal;Toxin
GO:0005509; GO:0005543; GO:0005576; GO:0006644; GO:0016042; GO:0042130; GO:0047498; GO:0050482; GO:0090729
Evidence at protein level
4
SUBCELLULAR LOCATION: Secreted.
SIGNAL 1..16; /evidence="ECO:0000255"
null
PF00068;
IPR001211;IPR033112;IPR016090;IPR036444;IPR033113;
null
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Viperidae (family), Crotalinae (subfamily), Crotalus (genus), Crotalus viridis (species)
null
true
Crotalus viridis
6
row_2061
false
null
3,972
P31987
AGEECDCGSPANPCCDAATCKLRPGAQCADGLCCDQCRFIKKGKICRRARGDNPDDRCTGQSADCPRNRFH
Disintegrin viridin (Platelet aggregation activation inhibitor)
Crotalus viridis viridis (Prairie rattlesnake)
8,742
71
7,638
Cell adhesion impairing toxin;Direct protein sequencing;Disulfide bond;Hemostasis impairing toxin;Platelet aggregation inhibiting toxin;Secreted;Toxin
GO:0005576; GO:0005886; GO:0090729
Evidence at protein level
3
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:8419314}.
null
null
PF00200;
IPR018358;IPR001762;IPR036436;
null
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Viperidae (family), Crotalinae (subfamily), Crotalus (genus), Crotalus viridis (species)
null
true
Crotalus viridis
7
row_3815
false
null
5,143
A2CJE6
NPCCDAATCKVRTGSQCAEGLCCDQCKFIKKGTVCRPARGDWNDDTCTGQSADCPRNGLYG
Disintegrin viridistatin
Crotalus viridis viridis (Prairie rattlesnake)
8,742
61
6,493
Cell adhesion impairing toxin;Disulfide bond;Hemostasis impairing toxin;Platelet aggregation inhibiting toxin;Secreted;Toxin
GO:0005576; GO:0005886; GO:0090729
Evidence at transcript level
2
SUBCELLULAR LOCATION: Secreted {ECO:0000305|PubMed:17112685}.
null
null
PF00200;
IPR018358;IPR001762;IPR036436;
null
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Viperidae (family), Crotalinae (subfamily), Crotalus (genus), Crotalus viridis (species)
null
true
Crotalus viridis
8
row_4910
false
null
3,289
P0C7N3
AMVTKNNGDLDKSGTECRLYCKDNSPGQNNSCKMFYSNEDEHKGMVLPGTK
Zinc metalloproteinase-disintegrin-like crovidisin (EC 3.4.24.-) (Snake venom metalloproteinase) (SVMP)
Crotalus viridis viridis (Prairie rattlesnake)
8,742
51
5,657
Apoptosis;Direct protein sequencing;Glycoprotein;Hemostasis impairing toxin;Hydrolase;Metal-binding;Metalloprotease;Platelet aggregation inhibiting toxin;Protease;Secreted;Toxin;Zinc
GO:0005576; GO:0006508; GO:0006915; GO:0008237; GO:0046872; GO:0090729
Evidence at protein level
3
SUBCELLULAR LOCATION: Secreted.
null
null
null
null
null
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Viperidae (family), Crotalinae (subfamily), Crotalus (genus), Crotalus viridis (species)
null
true
Crotalus viridis
9
row_3172
false
null
4,151
P63175
YKRCHKKEGHCFPKTVICLPPSSDFGKMDCRWKWKCCKKGSVNNA
Myotoxin-2 [Cleaved into: Myotoxin-4]
Crotalus viridis viridis (Prairie rattlesnake)
8,742
45
5,246
Antimicrobial;Direct protein sequencing;Disulfide bond;Ion channel impairing toxin;Myotoxin;Neurotoxin;Potassium channel impairing toxin;Secreted;Toxin;Voltage-gated potassium channel impairing toxin
GO:0005576; GO:0015459; GO:0044564; GO:0090729
Evidence at protein level
3
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:2253781}.
null
null
PF00819;
IPR023355;IPR000881;
null
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Viperidae (family), Crotalinae (subfamily), Crotalus (genus), Crotalus viridis (species)
null
true
Crotalus viridis
10
row_3986
false
null
1,335
P01476
YKQCHKKGGHCFPKEKICIPPSSDLGKMDCRWKWKCCKKGSG
Myotoxin-A (Myotoxin-1)
Crotalus viridis viridis (Prairie rattlesnake)
8,742
42
4,828
Antimicrobial;Direct protein sequencing;Disulfide bond;Ion channel impairing toxin;Myotoxin;Neurotoxin;Potassium channel impairing toxin;Secreted;Toxin;Voltage-gated potassium channel impairing toxin
GO:0005576; GO:0015459; GO:0044564; GO:0090729
Evidence at protein level
4
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:570412}.
null
null
PF00819;
IPR023355;IPR000881;
null
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Viperidae (family), Crotalinae (subfamily), Crotalus (genus), Crotalus viridis (species)
null
true
Crotalus viridis
11
row_1276
false
null
3,417
P0DJG6
VIGGDECNINEHRFLVALYDPDGFLSGGIL
Snake venom serine protease (SVSP) (EC 3.4.21.-)
Crotalus viridis viridis (Prairie rattlesnake)
8,742
30
3,235
Direct protein sequencing;Disulfide bond;Glycoprotein;Hydrolase;Hypotensive agent;Protease;Secreted;Serine protease;Toxin
GO:0005576; GO:0006508; GO:0008217; GO:0008236; GO:0090729
Evidence at protein level
3
SUBCELLULAR LOCATION: Secreted.
null
null
null
null
null
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Viperidae (family), Crotalinae (subfamily), Crotalus (genus), Crotalus viridis (species)
null
true
Crotalus viridis
12
row_3299
false
null
3,435
P0DJM5
NLVQFELLIMKVAKRSGLLSYSA
Acidic phospholipase A2 Cvv-E6c (svPLA2) (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase)
Crotalus viridis viridis (Prairie rattlesnake)
8,742
23
2,581
Calcium;Direct protein sequencing;Disulfide bond;Hemostasis impairing toxin;Hydrolase;Lipid degradation;Lipid metabolism;Metal-binding;Platelet aggregation inhibiting toxin;Secreted;Toxin
GO:0004623; GO:0005576; GO:0016042; GO:0046872; GO:0090729
Evidence at protein level
3
SUBCELLULAR LOCATION: Secreted.
null
null
null
null
null
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Viperidae (family), Crotalinae (subfamily), Crotalus (genus), Crotalus viridis (species)
null
true
Crotalus viridis
13
row_3313
false
null
3,286
P0C7K1
QGPSPRHPIPP
Bradykinin-potentiating peptide 11a (BPP-11a)
Crotalus viridis viridis (Prairie rattlesnake)
8,742
11
1,182
Direct protein sequencing;Hypotensive agent;Metalloenzyme inhibitor;Metalloprotease inhibitor;Protease inhibitor;Pyrrolidone carboxylic acid;Secreted;Toxin
GO:0005576; GO:0008217; GO:0030414; GO:0090729
Evidence at protein level
3
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:15912471}.
null
null
null
null
null
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Viperidae (family), Crotalinae (subfamily), Crotalus (genus), Crotalus viridis (species)
null
true
Crotalus viridis
14
row_3169
false
null
3,287
P0C7K2
QGGAPWNPIPP
Bradykinin-potentiating peptide 11b (BPP-11b)
Crotalus viridis viridis (Prairie rattlesnake)
8,742
11
1,133
Direct protein sequencing;Hypotensive agent;Metalloenzyme inhibitor;Metalloprotease inhibitor;Protease inhibitor;Pyrrolidone carboxylic acid;Secreted;Toxin
GO:0005576; GO:0008217; GO:0030414; GO:0090729
Evidence at protein level
3
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:15912471}.
null
null
null
null
null
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Viperidae (family), Crotalinae (subfamily), Crotalus (genus), Crotalus viridis (species)
null
true
Crotalus viridis
15
row_3170
false
null
3,288
P0C7K3
QSAPGNEAIPP
Bradykinin-potentiating peptide 11c (BPP-11c)
Crotalus viridis viridis (Prairie rattlesnake)
8,742
11
1,080
Direct protein sequencing;Hypotensive agent;Metalloenzyme inhibitor;Metalloprotease inhibitor;Protease inhibitor;Pyrrolidone carboxylic acid;Secreted;Toxin
GO:0005576; GO:0008217; GO:0030414; GO:0090729
Evidence at protein level
3
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:15912471}.
null
null
null
null
null
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Viperidae (family), Crotalinae (subfamily), Crotalus (genus), Crotalus viridis (species)
null
true
Crotalus viridis
16
row_3171
false
null
4,363
P85024
TPPAGPDVGPR
Bradykinin inhibitor peptide (BIP)
Crotalus viridis viridis (Prairie rattlesnake)
8,742
11
1,063
Bradykinin receptor impairing toxin;Direct protein sequencing;G-protein coupled receptor impairing toxin;Secreted;Toxin;Vasoactive
GO:0005576; GO:0044509; GO:0044551; GO:0090729; GO:0097746
Evidence at protein level
3
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:16277978}.
null
null
null
null
null
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Viperidae (family), Crotalinae (subfamily), Crotalus (genus), Crotalus viridis (species)
null
true
Crotalus viridis
17
row_4186
false
null
693
Q7NWF2
MRVENHSPSLSKLNPPEAGSGDPTAIGRRLSGIRRAPLPHVSAGSDGEAAAAGKIGAFLRKAVAAQSYGLMFANGKLFEATGDALEKRGQYGFSALQRLDGLSRRNLAAVEARLGALDSAERGLKERIMTGAWHFRHQSNAALDDGKTAAIASNHLLARESRSSGGNTFAGDKALLSNHDFVFFGVEFSGRGKQDKPLNHKHSTMDFGANAYVVPDTLPACRHGYLTLTDHFFNRVPGGREAEHQDFVGSFPQMGAETGRWIHEGKYRQNAPIFNYRDMKAAVALHLIEFLRDSKDAAFKAYVFDQAMQSGQALDRVLNSVFQAEFHIPRLMATTDYAKHPLRPMLLKEAVDSVNLPALSGLVSSKGDAVTAMWHAIDKGKDAVAAHLLGNWRFEAGDFASAPPGFYHELNYALSEHGASVYILDQFLSRGWAAVNAPFEHVNSGETMLDNAVKYGNREMAAALIKHGADRNLLSEWNGGKLDALLA
Arginine ADP-riboxanase CopC (EC 4.3.99.-)
Chromobacterium violaceum (strain ATCC 12472 / DSM 30191 / JCM 1249 / CCUG 213 / NBRC 12614 / NCIMB 9131 / NCTC 9757 / MK)
243,365
487
52,911
3D-structure;ANK repeat;Host cytoplasm;Lyase;Reference proteome;Repeat;Secreted;Toxin;Virulence
GO:0005516; GO:0005576; GO:0030430; GO:0052040; GO:0090729; GO:0140740
Evidence at protein level
5
SUBCELLULAR LOCATION: Secreted {ECO:0000250|UniProtKB:A0A0H2US87}. Host cytoplasm {ECO:0000250|UniProtKB:A0A0H2US87}. Note=Secreted via the type III secretion system (T3SS). {ECO:0000250|UniProtKB:A0A0H2US87}.
null
null
PF13606;PF06128;
IPR002110;IPR036770;IPR010366;
7WZS;7XN4;7XN5;7XN6;
cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Betaproteobacteria (class), Neisseriales (order), Chromobacteriaceae (family), Chromobacterium (genus), Chromobacterium violaceum (species)
copC CV_2038
true
Chromobacterium violaceum
0
row_648
false
null
4,542
Q2YHM1
MNYLTMISLALLVMTGVESGVRDAYIADNKNCIFTCYRDSYCKTECIKNGAETGYCIWIGEYGNACWCIKLPNKVPIKVPGKCNGR
Neurotoxin 8-related gene product 1/2/3 (Amm VIIIrgp1) (Amm VIIIrgp2) (Amm VIIIrgp3)
Androctonus mauritanicus mauritanicus (Scorpion)
6,860
86
9,598
Amidation;Disulfide bond;Ion channel impairing toxin;Neurotoxin;Secreted;Signal;Toxin;Voltage-gated sodium channel impairing toxin
GO:0005576; GO:0006952; GO:0019871; GO:0090729
Inferred from homology
3
SUBCELLULAR LOCATION: Secreted.
SIGNAL 1..19; /evidence="ECO:0000250"
null
PF00537;
IPR044062;IPR003614;IPR036574;IPR018218;IPR002061;
null
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Protostomia (clade), Ecdysozoa (clade), Panarthropoda (clade), Arthropoda (phylum), Chelicerata (subphylum), Arachnida (class), Scorpiones (order), Buthida (parvorder), Buthoidea (superfamily), Buthidae (family), Androctonus (genus), Androctonus mauritanicus (species)
NTVIIIrgp1
true
Androctonus mauritanicus
0
row_4343
false
null
707
Q7YXD3
MNYLVMISLALLFMTGVESLKDGYIVNDINCTYFCGRNAYCNELCIKLKGESGYCQWASPYGNSCYCYKLPDHVRTKGPGRCNDR
Alpha-toxin Amm8 (Alpha-anatoxin Amm VIII) (Amm VIII) (AmmVIII) (Neurotoxin 8) (P4)
Androctonus mauritanicus mauritanicus (Scorpion)
6,860
85
9,654
Direct protein sequencing;Disulfide bond;Ion channel impairing toxin;Neurotoxin;Secreted;Signal;Toxin;Voltage-gated sodium channel impairing toxin
GO:0005576; GO:0006952; GO:0019871; GO:0090729
Evidence at protein level
5
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:12911331}.
SIGNAL 1..19; /evidence="ECO:0000269|PubMed:12911331"
null
PF00537;
IPR044062;IPR003614;IPR036574;IPR018218;IPR002061;
null
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Protostomia (clade), Ecdysozoa (clade), Panarthropoda (clade), Arthropoda (phylum), Chelicerata (subphylum), Arachnida (class), Scorpiones (order), Buthida (parvorder), Buthoidea (superfamily), Buthidae (family), Androctonus (genus), Androctonus mauritanicus (species)
null
true
Androctonus mauritanicus
1
row_661
false
null
1,561
P0DPT3
EHGYLLDKYTGCKVWCVINNESCNGECNKRRGGYYGYCYFWKLACYCQGARKSELWNYKTNKCKS
Beta-toxin Am IT (Am IT)
Androctonus mauritanicus mauritanicus (Scorpion)
6,860
65
7,699
Amidation;Direct protein sequencing;Disulfide bond;Ion channel impairing toxin;Neurotoxin;Pyrrolidone carboxylic acid;Secreted;Toxin;Voltage-gated sodium channel impairing toxin
GO:0005576; GO:0006952; GO:0019871; GO:0090729
Evidence at protein level
4
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:26109302}.
null
null
PF00537;
IPR044062;IPR003614;IPR036574;IPR018218;IPR002061;
null
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Protostomia (clade), Ecdysozoa (clade), Panarthropoda (clade), Arthropoda (phylum), Chelicerata (subphylum), Arachnida (class), Scorpiones (order), Buthida (parvorder), Buthoidea (superfamily), Buthidae (family), Androctonus (genus), Androctonus mauritanicus (species)
null
true
Androctonus mauritanicus
2
row_1495
false
null
3,092
P01482
LKDGYIIDDLNCTFFCGRNAYCDDECKKKGGESGYCQWASPYGNACWCYKLPDRVSIKEKGRCN
Alpha-toxin Amm5 (Amm V) (AmmV) (Neurotoxin 5) (Neurotoxin V)
Androctonus mauritanicus mauritanicus (Scorpion)
6,860
64
7,301
Amidation;Direct protein sequencing;Disulfide bond;Ion channel impairing toxin;Neurotoxin;Secreted;Toxin;Voltage-gated sodium channel impairing toxin
GO:0005576; GO:0006952; GO:0019871; GO:0090729
Evidence at protein level
3
SUBCELLULAR LOCATION: Secreted.
null
null
PF00537;
IPR044062;IPR003614;IPR036574;IPR018218;IPR002061;
null
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Protostomia (clade), Ecdysozoa (clade), Panarthropoda (clade), Arthropoda (phylum), Chelicerata (subphylum), Arachnida (class), Scorpiones (order), Buthida (parvorder), Buthoidea (superfamily), Buthidae (family), Androctonus (genus), Androctonus mauritanicus (species)
null
true
Androctonus mauritanicus
3
row_2990
false
null
3,324
P0C910
GRDGYIVDTKNCVYHCYPPCDGLCKKNQAKSGSCGFLYPSGLACWCVALPENVPIKDPNDDCHK
Alpha-toxin Amm3 (Amm III)
Androctonus mauritanicus mauritanicus (Scorpion)
6,860
64
7,009
Direct protein sequencing;Disulfide bond;Ion channel impairing toxin;Neurotoxin;Secreted;Toxin;Voltage-gated sodium channel impairing toxin
GO:0005576; GO:0006952; GO:0019871; GO:0090729
Evidence at protein level
3
SUBCELLULAR LOCATION: Secreted.
null
null
PF00537;
IPR044062;IPR003614;IPR036574;IPR002061;
null
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Protostomia (clade), Ecdysozoa (clade), Panarthropoda (clade), Arthropoda (phylum), Chelicerata (subphylum), Arachnida (class), Scorpiones (order), Buthida (parvorder), Buthoidea (superfamily), Buthidae (family), Androctonus (genus), Androctonus mauritanicus (species)
null
true
Androctonus mauritanicus
4
row_3206
false
null
3,922
P24662
GVEINVKCSGSPQCLKPCKDAGMRFGKCMNRKCHCTPK
Potassium channel toxin alpha-KTx 3.1 (Kaliotoxin) (KTX) (Kaliotoxin-1) (KTX-1)
Androctonus mauritanicus mauritanicus (Scorpion)
6,860
38
4,156
3D-structure;Direct protein sequencing;Disulfide bond;Ion channel impairing toxin;Neurotoxin;Potassium channel impairing toxin;Secreted;Toxin;Voltage-gated potassium channel impairing toxin
GO:0005576; GO:0008200; GO:0015459; GO:0090729
Evidence at protein level
3
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:1730708}.
null
null
PF00451;
IPR036574;IPR001947;
1KTX;1XSW;2KTX;2UVS;3ODV;
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Protostomia (clade), Ecdysozoa (clade), Panarthropoda (clade), Arthropoda (phylum), Chelicerata (subphylum), Arachnida (class), Scorpiones (order), Buthida (parvorder), Buthoidea (superfamily), Buthidae (family), Androctonus (genus), Androctonus mauritanicus (species)
null
true
Androctonus mauritanicus
5
row_3767
false
null
1,785
P60208
QIETNKKCQGGSCASVCRKVIGVAAGKCINGRCVCYP
Potassium channel toxin alpha-KTx 15.3 (Toxin AmmTX3)
Androctonus mauritanicus mauritanicus (Scorpion)
6,860
37
3,846
3D-structure;Direct protein sequencing;Disulfide bond;Ion channel impairing toxin;Neurotoxin;Potassium channel impairing toxin;Pyrrolidone carboxylic acid;Secreted;Toxin;Voltage-gated potassium channel impairing toxin
GO:0005576; GO:0008200; GO:0015459; GO:0090729
Evidence at protein level
4
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:12473099}.
null
null
PF00451;
IPR036574;IPR001947;
6GGZ;
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Protostomia (clade), Ecdysozoa (clade), Panarthropoda (clade), Arthropoda (phylum), Chelicerata (subphylum), Arachnida (class), Scorpiones (order), Buthida (parvorder), Buthoidea (superfamily), Buthidae (family), Androctonus (genus), Androctonus mauritanicus (species)
null
true
Androctonus mauritanicus
6
row_1711
false
null
6,051
P01498
CGPCFTTDPYTESKCATCCGGRGKCVGPQCLCNRI
Peptide P2 (AmmP2)
Androctonus mauritanicus mauritanicus (Scorpion)
6,860
35
3,673
Chloride channel impairing toxin;Direct protein sequencing;Disulfide bond;Ion channel impairing toxin;Knottin;Secreted;Toxin;Voltage-gated chloride channel impairing toxin
GO:0005576; GO:0017081; GO:0090729
Evidence at protein level
2
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:3992595}.
null
null
PF05294;
IPR036574;IPR007958;
null
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Protostomia (clade), Ecdysozoa (clade), Panarthropoda (clade), Arthropoda (phylum), Chelicerata (subphylum), Arachnida (class), Scorpiones (order), Buthida (parvorder), Buthoidea (superfamily), Buthidae (family), Androctonus (genus), Androctonus mauritanicus (species)
null
true
Androctonus mauritanicus
7
row_5810
false
null
1,699
P31719
TVCNLRRCQLSCRSLGLLGKCIGVKCECVKH
Potassium channel toxin alpha-KTx 5.2 (AmPO5) (P05) (PO5) (Leiurotoxin I-like toxin P05)
Androctonus mauritanicus mauritanicus (Scorpion)
6,860
31
3,421
3D-structure;Calcium-activated potassium channel impairing toxin;Direct protein sequencing;Disulfide bond;Ion channel impairing toxin;Neurotoxin;Potassium channel impairing toxin;Secreted;Toxin
GO:0005576; GO:0008200; GO:0015459; GO:0090729
Evidence at protein level
4
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:8385026}.
null
null
PF00451;
IPR036574;IPR001947;
1PNH;
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Protostomia (clade), Ecdysozoa (clade), Panarthropoda (clade), Arthropoda (phylum), Chelicerata (subphylum), Arachnida (class), Scorpiones (order), Buthida (parvorder), Buthoidea (superfamily), Buthidae (family), Androctonus (genus), Androctonus mauritanicus (species)
null
true
Androctonus mauritanicus
8
row_1628
false
null
4,028
P56215
VSCEDCPEHCSTQKAQAKCDNDKCVCEPI
Potassium channel toxin alpha-KTx 8.1 (AmP01) (P01) (PO1)
Androctonus mauritanicus mauritanicus (Scorpion)
6,860
29
3,185
3D-structure;Calcium-activated potassium channel impairing toxin;Direct protein sequencing;Disulfide bond;Ion channel impairing toxin;Neurotoxin;Potassium channel impairing toxin;Secreted;Toxin
GO:0005576; GO:0008200; GO:0015459; GO:0090729
Evidence at protein level
3
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:8985784}.
null
null
PF05453;
IPR036574;IPR008911;
1ACW;
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Protostomia (clade), Ecdysozoa (clade), Panarthropoda (clade), Arthropoda (phylum), Chelicerata (subphylum), Arachnida (class), Scorpiones (order), Buthida (parvorder), Buthoidea (superfamily), Buthidae (family), Androctonus (genus), Androctonus mauritanicus (species)
null
true
Androctonus mauritanicus
9
row_3868
false
null
709
Q7ZTA7
MRTLWIVAVLLLGVEGSLVQFEMLIMKVAKRSGLFSYSAYGCYCGWGGHGRPQDATDHCCFVHDCCYGKVTDCNPKTASYTYSEENGEIVCGGDDPCKKQVCECDRVAAICFRDNIPTYDNKYWRFPPENCQEEPEPC
Acidic phospholipase A2 CoaPLA2 (svPLA2) (EC 3.1.1.4) (Cvv-E6d) (Phosphatidylcholine 2-acylhydrolase) (Phospholipase A2 CoaTx-I)
Crotalus lutosus abyssus (Grand Canyon rattlesnake) (Crotalus oreganus abyssus)
128,077
138
15,549
Calcium;Direct protein sequencing;Disulfide bond;Hemostasis impairing toxin;Hydrolase;Lipid degradation;Lipid metabolism;Metal-binding;Myotoxin;Platelet aggregation inhibiting toxin;Secreted;Signal;Toxin
GO:0005509; GO:0005543; GO:0005576; GO:0006644; GO:0016042; GO:0042130; GO:0047498; GO:0050482; GO:0090729
Evidence at protein level
5
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:12623078}.
SIGNAL 1..16; /evidence="ECO:0000269|PubMed:12623078"
null
PF00068;
IPR001211;IPR033112;IPR016090;IPR036444;IPR033113;
null
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Viperidae (family), Crotalinae (subfamily), Crotalus (genus), Crotalus lutosus (species)
null
true
Crotalus lutosus
0
row_663
false
null
1,612
P0DUP2
SLVELGKMILQETGKNAIPSYGFYGCNCGWGGRGKPKDATDRCCFVHKCCYKKLTDCDPKTDIYSYSWKNKTIICDVNNPCLKEMCECDKAVAICLRENLDTYNKKYRIYPKFLCKKPDTC
Basic phospholipase A2 CoaTx-II (svPLA2 homolog) (Lys49 PLA2-like)
Crotalus lutosus abyssus (Grand Canyon rattlesnake) (Crotalus oreganus abyssus)
128,077
121
13,866
Antibiotic;Antimicrobial;Direct protein sequencing;Disulfide bond;Myotoxin;Secreted;Toxin
GO:0005509; GO:0005543; GO:0005576; GO:0006644; GO:0016042; GO:0042130; GO:0042742; GO:0047498; GO:0050482; GO:0090729
Evidence at protein level
4
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:27530662}.
null
null
PF00068;
IPR001211;IPR033112;IPR016090;IPR036444;IPR033113;
null
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Viperidae (family), Crotalinae (subfamily), Crotalus (genus), Crotalus lutosus (species)
null
true
Crotalus lutosus
1
row_1545
false
null
2,582
B3EWY2
SYGISSGCFGLKLDRIGTMSGLGCWRLLQDSP
Natriuretic peptide Coa_NP2
Crotalus lutosus abyssus (Grand Canyon rattlesnake) (Crotalus oreganus abyssus)
128,077
32
3,419
Direct protein sequencing;Disulfide bond;Hypotensive agent;Secreted;Toxin;Vasoactive;Vasodilator
GO:0005179; GO:0005576; GO:0008217; GO:0042311; GO:0090729; GO:0097746
Evidence at protein level
3
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:22617223}.
null
null
PF00212;
IPR000663;IPR030480;IPR002408;
null
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Viperidae (family), Crotalinae (subfamily), Crotalus (genus), Crotalus lutosus (species)
null
true
Crotalus lutosus
2
row_2494
false
null
2,583
B3EWY3
SKRLSNGCFGLKLDRIGAMSGLGCWRLINESK
Natriuretic peptide Coa_NP1
Crotalus lutosus abyssus (Grand Canyon rattlesnake) (Crotalus oreganus abyssus)
128,077
32
3,511
Direct protein sequencing;Disulfide bond;Hypotensive agent;Secreted;Toxin;Vasoactive;Vasodilator
GO:0005179; GO:0005576; GO:0008217; GO:0042311; GO:0090729; GO:0097746
Evidence at protein level
3
SUBCELLULAR LOCATION: Secreted {ECO:0000269|Ref.1}.
null
null
PF00212;
IPR000663;IPR030480;IPR002408;
null
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Viperidae (family), Crotalinae (subfamily), Crotalus (genus), Crotalus lutosus (species)
null
true
Crotalus lutosus
3
row_2495
false
null
753
Q95P65
MKSLIGTLGLYCLFILTNNVVSSYGDDLYPLTIMHTNDFHARFEETNVKGNPCKSGEKCIGGLARVLHTIKKIIKEQEKKNIESLYINAGDNFQGTIWYNIGRWNVTSELMNIQPPDVMVLGNHEFDHGIDGLLPFLNNMDKTEIVVANMDARDEPQVAKKIKPFTIIKKKYRNIGVIGVVVEEVPDLANTGKLKFRNESEAILEAARNLKKEDPSVNIIIVVSHVGFDVDKIIAERTGSEVDIIVGGHSHTVLYTGTPPGPEKPEDNYPYVYNHPSGNKVLVVQAVCHAKYVGNLTVFFDKKGKVVTYEGAPIYMDTKVEQDKDVLEAMKPWRKLIDEKTKLVVGRTNVDLPRDICRSEECALGNLYTDSMIYAFGGKENCKSGSTWTTAPIAFVHAGAMRSSLHQGDILYSDALLLSPFTNMVVAYDLPGAQLKAALEFSAAPKNEDEKRRFLQMSGLKVTYNMSRAANNRIVDLKVRTNVCPYDQYENLDEKKTYRVVSPSFLQGGGDGFKMLRDYAKNIQNQKIDLDALVDYLKKFSPLAPKAEGRITIIH
5'-nucleotidase-related protein (5'Nuc) (EC 3.6.1.5)
Glossina morsitans morsitans (Savannah tsetse fly)
37,546
555
62,064
Glycoprotein;Hemostasis impairing toxin;Hydrolase;Metal-binding;Nucleotide-binding;Platelet aggregation inhibiting toxin;Secreted;Signal;Toxin;Zinc
GO:0000166; GO:0000287; GO:0004050; GO:0005178; GO:0005615; GO:0005886; GO:0006196; GO:0008253; GO:0030145; GO:0035893; GO:0090729
Evidence at protein level
5
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:20351782}.
SIGNAL 1..25; /evidence="ECO:0000255"
null
PF02872;PF00149;
IPR008334;IPR036907;IPR006146;IPR006179;IPR004843;IPR029052;
null
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Protostomia (clade), Ecdysozoa (clade), Panarthropoda (clade), Arthropoda (phylum), Mandibulata (clade), Pancrustacea (clade), Hexapoda (subphylum), Insecta (class), Dicondylia (clade), Pterygota (subclass), Neoptera (infraclass), Endopterygota (cohort), Diptera (order), Brachycera (suborder), Muscomorpha (infraorder), Eremoneura (clade), Cyclorrhapha (clade), Schizophora (no rank), Calyptratae (no rank), Hippoboscoidea (superfamily), Glossinidae (family), Glossina (genus), Glossina (subgenus), Glossina morsitans (species)
null
true
Glossina morsitans
0
row_706
false
null
818
A0A0H3B1Q8
MKISPNTISPSQSDPRMSTNVSQRSRVSGIGVPVSHSINNPSIQHVQDFATLSARSLRANVLLNSDDHSVPIHAKNPSELLEAIDNNISQTAQDWGVSIQEVEVILGSSKRIIEPVCGVTANTIMKLFLDNDIFSYSFEKGQSLSLSQLQERLASLPAHKNFILRVNDGGLGHAYVIDFPATTNPSRDAFLYQSDLGEGVTREVRFEDWMTQKASHPISLDDINTHFIGIAQDQIDLAHIAKLFDVDGNVKMLRADHLISHKTSEFNFQLFEYDLKNLENNMSIIKTHCN
Protein-glutamine deamidase Cif (EC 3.5.1.44) (Cycle-inhibiting factor homolog) (CHYP)
Yersinia pseudotuberculosis serotype O:3 (strain YPIII)
502,800
290
32,280
3D-structure;Host nucleus;Hydrolase;Secreted;Toxin;Virulence
GO:0005576; GO:0016787; GO:0042025; GO:0044071; GO:0090729
Evidence at protein level
4
SUBCELLULAR LOCATION: Secreted {ECO:0000250|UniProtKB:P0DUW5}. Host nucleus {ECO:0000250|UniProtKB:P0DUW5}. Note=Secreted via the type III secretion system (T3SS). {ECO:0000250|UniProtKB:P0DUW5}.
null
null
PF16374;
IPR032278;
4F8C;
cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Gammaproteobacteria (class), Enterobacterales (order), Yersiniaceae (family), Yersinia (genus), Yersinia pseudotuberculosis complex (no rank), Yersinia pseudotuberculosis (species)
cif YPK_1971
true
Yersinia pseudotuberculosis
0
row_767
false
null
891
A3UNN4
MNTRFLLLLCCLSFTTFSQPFDAIKQPNRSEEEVTQLAEDFKDWSKASNGWRYSFITANEKEAVEDFSISGYQTANDYLRATDTSTWGVAGADARQYIRTVKSALNKLPKYKGTAYRGTWVKLSLLNKLEEGDVLVEPAFTSTSTLPEVAKRFSVVHPNSPQRLKRVLFEVKINQGGHTIAGLSEYSKEAEVLFAPNAHFRITQIERTSNHTYIGVETVKASAVKNTQKYNLYSGEEVEASFWHSLVCT
Putative NAD(+)--arginine ADP-ribosyltransferase Vis (EC 2.4.2.31) (Putative mono(ADP-ribosyl)transferase) (mADPRT) (mART) (Toxin Vis)
Vibrio splendidus (strain 12B01)
314,291
249
28,087
3D-structure;Glycosyltransferase;NAD;NADP;Nucleotide-binding;Nucleotidyltransferase;Secreted;Signal;Toxin;Transferase;Virulence
GO:0000166; GO:0005576; GO:0016779; GO:0090729; GO:0106274
Evidence at protein level
4
SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
SIGNAL 1..18; /evidence="ECO:0000255"
null
PF03496;
IPR003540;
4XZJ;4XZK;4Y1W;4YC0;
cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Gammaproteobacteria (class), Vibrionales (order), Vibrionaceae (family), Vibrio (genus), Vibrio splendidus (species)
V12B01_18061
true
Vibrio splendidus
0
row_838
false
null
905
A8GG78
MSELSAARELDEIAHTASEGWMIAGLIGGAIVGAALIAVTGGTAAVAVAAVVAGASAGGGLGEVLGSMSWAPRHVTGVLADGSPNVYINGRPAIRAHISTGECSEDGPAKKVVAQGSAKVYINDFPAARINDLLACSAEIHTGSPNVIIGGEKEQTDDIEPEIPDWVNWTLLAAGAGAAAVLATPAIAILGTLGGLGGGFAGSLIGGAFFGEGSDGQKWSMLAGGFVGGFAGGKGGAKFDAWRNTKIVEPPPRVTTKVDPISPPRMTLAEAVGQEQAKVWTQTARANAEKNNAQLSTLLTDDQIGAIYGYTTNEGYTALNPALRGQTPLTPELEAFTGHVTDGLNKLPAYNGETYRGTTLPAHILEQNQIGGTVSDGGFMSTSAKTPFDGDVSISVRGNSGKQIDFLSKYKNEAEVLYPPNTRFEVINRIEQNGTTHLLYREIP
NAD(+)--protein-arginine ADP-ribosyltransferase Tre1 (EC 2.4.2.31) (Effector protein Tre1) (Tre1-Sp) (Type VI secretion ADP-ribosyltransferase effector 1)
Serratia proteamaculans (strain 568)
399,741
444
45,824
3D-structure;Glycosyltransferase;Host cytoplasm;Nucleotidyltransferase;Secreted;Toxin;Transferase;Virulence
GO:0003950; GO:0005576; GO:0016779; GO:0030430; GO:0090729; GO:0106274
Evidence at protein level
4
SUBCELLULAR LOCATION: Secreted {ECO:0000305}. Host cytoplasm {ECO:0000305}. Note=Probably delivered to target cells by a type 6 secretion system (T6SS). {ECO:0000305|PubMed:30343895}.
null
null
PF01129;PF05488;
IPR050999;IPR000768;IPR008727;
6DRE;6DRH;
cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Gammaproteobacteria (class), Enterobacterales (order), Yersiniaceae (family), Serratia (genus), Serratia proteamaculans (species)
tre1 Spro_3017
true
Serratia proteamaculans
0
row_852
false
null
2,484
B0VXW0
MNVFFMFSLLFLAALGSCADDRNPLEECFRETDYEEFLEIAKNGLTATSNPKRVVIVGAGMSGLSAAYVLAGAGHQVTVLEASERVGGRVRTYRKEDWYANLGPMRLPTKHRIVREYIKKFGLELNEFFQENDNAWYFIKNIRKRVQEVKNNPGLLKYPVKPSETGKSAGQLYEESLRKVVEELRSTNCKYILDKYDTYSTKEYLLKEGNLSPGAVDMIGDLLNEDSGYYVSFIESLKHDDIFGYEKRFDEIVGGMDQLPTSMYEAIKEKVQVHFNARVIEIQQNDREATVTYQTSANEMSSVTADYVIVCTTSRAARRIKFEPPLPPKKAHALRSVHYRSGTKIFLTCTKKFWEDEGIHGGKSTTDLPSRSIYYPNHNFTSGVGVIIAYGIGDDANFFQALDFKDCADIVINDLSLIHQLPKEDIQTFCHPSKIQRWSLDRYAMGGITTFTPYQFQHFSEALTAPFNRIYFAGEYTAQFHGWIDSTIKSGLTAARDVNRASENPSGIHLSNDNEF
L-amino-acid oxidase (LAAO) (LAO) (EC 1.4.3.2)
Sistrurus catenatus edwardsii (Desert massasauga) (Crotalophorus edwardsii)
8,762
516
58,569
Antibiotic;Antimicrobial;Apoptosis;Cytolysis;Disulfide bond;FAD;Flavoprotein;Glycoprotein;Hemolysis;Hemostasis impairing toxin;Oxidoreductase;Secreted;Signal;Toxin
GO:0001716; GO:0005576; GO:0006915; GO:0009063; GO:0031640; GO:0042742; GO:0090729
Evidence at transcript level
3
SUBCELLULAR LOCATION: Secreted {ECO:0000305|PubMed:18096037}.
SIGNAL 1..18; /evidence="ECO:0000255"
null
PF01593;
IPR002937;IPR036188;IPR050281;
null
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Viperidae (family), Crotalinae (subfamily), Sistrurus (genus), Sistrurus catenatus (species)
null
true
Sistrurus catenatus
0
row_2397
false
null
5,248
B0VXV6
MIALIVLPILAAVLQQSSGSVDFDSESPRKPEIQNKIVDLHNSLRRSVNPTASNMLKMEWYSEAAANAERWAYRCIESHSPRDSRVLEGIKCGENIYMSSVPMKWTEIIHIWHGENKNFKYGIGADPPNAVTGHYTQIVWYKSYRAGCAAAYCPSLEYSYFYVCQYCPAGNIRGKTATPYKSGPPCGDCPSACDNGLCTNPCPKKISTQLPRFGPQAGCQDKQMQSDCSATCFCQNKII
Cysteine-rich venom protein 2 (CRVP) (Cysteine-rich secretory protein 2) (CRISP-2)
Sistrurus catenatus edwardsii (Desert massasauga) (Crotalophorus edwardsii)
8,762
239
26,542
Calcium channel impairing toxin;Disulfide bond;Ion channel impairing toxin;Neurotoxin;Secreted;Signal;Toxin
GO:0005246; GO:0005576; GO:0090729
Evidence at transcript level
2
SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
SIGNAL 1..19; /evidence="ECO:0000250"
null
PF00188;PF08562;
IPR018244;IPR014044;IPR035940;IPR042076;IPR001283;IPR013871;IPR034117;IPR003582;IPR002413;
null
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Viperidae (family), Crotalinae (subfamily), Sistrurus (genus), Sistrurus catenatus (species)
null
true
Sistrurus catenatus
1
row_5015
false
null
915
B0VXV8
MFVSRLAASGLLLLALLAVSLDGKPVQQWSQNWPGPKVPPLVVQQWSQNWPHPQIPPLVVQNWKSPTQLQPRESPAGGTTALREELSLGPDAALDTPPAGPDVGPRGSKAAAAPQRLSKSKGASATSTASRPMRDLRTDGKQARQNWGRMLNPDHHSAPGGGGGGGGGGARRLKGLAKKRAGSGCFGLKLDRIGSMSGLGC
Bradykinin potentiating and C-type natriuretic peptides (BPP-CNP) [Cleaved into: Bradykinin-potentiating peptide 10c (BPP-10c) (BPP-2) (Bradykinin-potentiating peptide-1) (BPP-1); Bradykinin-potentiating peptide-2 (BPP-2); Bradykinin inhibitor peptide homolog; C-type natriuretic peptide (CNP)]
Sistrurus catenatus edwardsii (Desert massasauga) (Crotalophorus edwardsii)
8,762
201
20,896
Cleavage on pair of basic residues;Disulfide bond;Hypotensive agent;Metalloenzyme inhibitor;Metalloprotease inhibitor;Protease inhibitor;Pyrrolidone carboxylic acid;Secreted;Signal;Toxin;Vasoactive;Vasodilator
GO:0005179; GO:0005576; GO:0006182; GO:0007168; GO:0008217; GO:0030414; GO:0042311; GO:0090729
Evidence at transcript level
4
SUBCELLULAR LOCATION: Secreted {ECO:0000305|PubMed:18096037}.
SIGNAL 1..23; /evidence="ECO:0000255"
null
PF00212;
IPR000663;IPR030480;
null
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Viperidae (family), Crotalinae (subfamily), Sistrurus (genus), Sistrurus catenatus (species)
null
true
Sistrurus catenatus
2
row_862
false
null
5,247
B0VXV2
MGRLVFVSFSLLVVFLSLSGTAADCPSGWSSYEGHCYKPFNEPKNWDDAERFCLEQAKGGHLVSIESSEEADFVAQLVANNVRRGISYIWIGLRVQGEEKQCSTKWSDGSSVNYENWIEALSKTCLGLEQDTNHKWVNIYCGEINPFVCKA
Snaclec 3 (C-type lectin isoform 3)
Sistrurus catenatus edwardsii (Desert massasauga) (Crotalophorus edwardsii)
8,762
151
16,939
Disulfide bond;Hemostasis impairing toxin;Secreted;Signal;Toxin
GO:0005576; GO:0090729
Evidence at transcript level
2
SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
SIGNAL 1..23; /evidence="ECO:0000255"
null
PF00059;
IPR001304;IPR016186;IPR050111;IPR018378;IPR016187;
null
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Viperidae (family), Crotalinae (subfamily), Sistrurus (genus), Sistrurus catenatus (species)
null
true
Sistrurus catenatus
3
row_5014
false
null
913
B0VXV3
MAAYLLAVAILFCIQGWPSGTVQGQAMPFMEVFERSVCQTREMLVSILDEHPDEVAHLFRPSCVTVLRCGGCCTDESLMCTATGKRSVGREIMRVDPRKETSKIQVMQFTEHTKCECRPRSGRVNSGKRKRNPEEGGAESQVPLGLTSF
Snake venom vascular endothelial growth factor toxin 1 (svVEGF) (VEGF-F)
Sistrurus catenatus edwardsii (Desert massasauga) (Crotalophorus edwardsii)
8,762
149
16,557
Disulfide bond;Growth factor;Pyrrolidone carboxylic acid;Secreted;Signal;Toxin
GO:0001666; GO:0001938; GO:0002040; GO:0005172; GO:0005615; GO:0008083; GO:0016020; GO:0038084; GO:0042056; GO:0045766; GO:0048010; GO:0050930; GO:0060754; GO:0090729
Evidence at transcript level
4
SUBCELLULAR LOCATION: Secreted {ECO:0000305|PubMed:18096037}.
SIGNAL 1..24; /evidence="ECO:0000255"
null
PF00341;
IPR029034;IPR023581;IPR000072;IPR050507;
null
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Viperidae (family), Crotalinae (subfamily), Sistrurus (genus), Sistrurus catenatus (species)
null
true
Sistrurus catenatus
4
row_860
false
null
5,245
B0VXV0
MGRFIFMSFGLLVVFLSLSGTGADCPSDWSSYEGHCYRVFQQEMTWEAAEQFCAQQRKESHLVSFHSSEEVDFLVSITYPILKADLVWIGLRDIWNECRLEWTDGTKVDYKEWSEEPECIVSKTTDNQWISRPCSRTYSFVCKFQA
Snaclec 1 (C-type lectin isoform 1)
Sistrurus catenatus edwardsii (Desert massasauga) (Crotalophorus edwardsii)
8,762
146
17,054
Disulfide bond;Hemostasis impairing toxin;Secreted;Signal;Toxin
GO:0005576; GO:0090729
Evidence at transcript level
2
SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
SIGNAL 1..23; /evidence="ECO:0000255"
null
PF00059;
IPR001304;IPR016186;IPR050111;IPR018378;IPR016187;
null
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Viperidae (family), Crotalinae (subfamily), Sistrurus (genus), Sistrurus catenatus (species)
null
true
Sistrurus catenatus
5
row_5012
false
null
5,246
B0VXV1
MGRFIFVSFSLLVVFLSLSGTGAHCPSGWYTYEGHCYRVFQQNMTWEDAEKFCTQQYEKSHLVSFRSSEEVDFLVSLLKVDLFWMGRRDIWNERRLQWSDGTKVDYKDWRAKPECIVCRATDNHWLSTSCSETHNVICKFET
Snaclec 2 (C-type lectin isoform 2)
Sistrurus catenatus edwardsii (Desert massasauga) (Crotalophorus edwardsii)
8,762
142
16,817
Disulfide bond;Glycoprotein;Hemostasis impairing toxin;Secreted;Signal;Toxin
GO:0005576; GO:0090729
Evidence at transcript level
2
SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
SIGNAL 1..23; /evidence="ECO:0000255"
null
PF00059;
IPR001304;IPR016186;IPR050111;IPR018378;IPR016187;
null
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Viperidae (family), Crotalinae (subfamily), Sistrurus (genus), Sistrurus catenatus (species)
null
true
Sistrurus catenatus
6
row_5013
false
null