Unnamed: 0
int64 2
562k
| Entry
stringlengths 6
10
| Sequence
stringlengths 11
999
| Protein names
stringlengths 5
558
| Organism
stringclasses 392
values | Organism (ID)
int64 595
2.89M
| Length
int64 11
999
| Mass
int64 1.06k
118k
| Keywords
stringlengths 4
380
⌀ | Gene Ontology IDs
stringlengths 10
754
⌀ | Protein existence
stringclasses 5
values | Annotation
float64 1
5
| Subcellular location [CC]
stringlengths 30
2.26k
⌀ | Signal peptide
stringclasses 677
values | Transmembrane
stringlengths 32
2.52k
⌀ | Pfam
stringlengths 8
72
⌀ | InterPro
stringlengths 10
180
⌀ | PDB
stringlengths 5
2.65k
⌀ | Taxonomic lineage
stringclasses 178
values | Gene Names
stringlengths 2
299
⌀ | Toxin
bool 2
classes | species
stringclasses 111
values | cdhit_cluster
int64 0
4.65k
| cdhit_rep
stringlengths 5
10
| cdhit_rep_is_ref
bool 1
class | cdhit_pct_id
float64 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
7,268 |
Q719L8
|
MGRLVFVSFGLLVVFLSLTGTGAGFCCPLGWSSYEGHCYKVFKQDMTWEDAEKFCTQQHEGSHLVSLQSSEEVDFVISMTAPMLKLGLVWIGLSNIWNECTLEWTNGNKVDYKAWSAEPECIVSKSTDKHWFSRPCSKTHKVVCKFQA
|
Snaclec crotocetin (CRC)
|
Crotalus durissus terrificus (South American rattlesnake)
| 8,732 | 148 | 16,728 |
Disulfide bond;Hemostasis impairing toxin;Secreted;Signal;Toxin
|
GO:0005576; GO:0090729
|
Evidence at transcript level
| 2 |
SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
|
SIGNAL 1..23; /evidence="ECO:0000250"
| null |
PF00059;
|
IPR001304;IPR016186;IPR050111;IPR018378;IPR016187;
| null |
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Viperidae (family), Crotalinae (subfamily), Crotalus (genus), Crotalus durissus (species)
| null | true |
Crotalus durissus
| 15 |
row_6989
| false | null |
227 |
P08878
|
MRALWIVAVLLVGVEGSLVEFETLMMKIAGRSGISYYSSYGCYCGAGGQGWPQDASDRCCFEHDCCYAKLTGCDPTTDVYTYRQEDGEIVCGEDDPCGTQICECDKAAAICFRNSMDTYDYKYLQFSPENCQGESQPC
|
Phospholipase A2 homolog crotoxin acid subunit CA (CTX subunit CA) (Crotapotin) [Cleaved into: Crotoxin chain alpha CA1, CA2 and CA4; Crotoxin chain alpha CA3; Crotoxin chain beta CA2, CA3 and CA4; Crotoxin chain beta CA1; Crotoxin chain gamma (Analgesic peptide) (Crotalphine)]
|
Crotalus durissus terrificus (South American rattlesnake)
| 8,732 | 138 | 15,273 |
3D-structure;Direct protein sequencing;Disulfide bond;G-protein coupled receptor impairing toxin;Neurotoxin;Pharmaceutical;Presynaptic neurotoxin;Pyrrolidone carboxylic acid;Secreted;Signal;Toxin
|
GO:0005509; GO:0005543; GO:0005576; GO:0006644; GO:0016042; GO:0042130; GO:0047498; GO:0050482; GO:0090729
|
Evidence at protein level
| 5 |
SUBCELLULAR LOCATION: Secreted.
|
SIGNAL 1..37; /evidence="ECO:0000269|PubMed:1868083"
| null |
PF00068;
|
IPR001211;IPR033112;IPR016090;IPR036444;IPR033113;
|
3R0L;
|
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Viperidae (family), Crotalinae (subfamily), Crotalus (genus), Crotalus durissus (species)
| null | true |
Crotalus durissus
| 16 |
row_212
| false | null |
399 |
P24027
|
MRALWIVAVLLVGVEGSLLQFNKMIKFETRKNAVPFYAFYGCYCGWGGQGRPKDATDRCCFVHDCCYGKLAKCNTKWDIYRYSLKSGYITCGKGTWCKEQICECDRVAAECLRRSLSTYKNEYMFYPDSRCREPSETC
|
Phospholipase A2 crotoxin basic chain CBa2 (CB2) (CTX subunit CBa2) (svPLA2) (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase)
|
Crotalus durissus terrificus (South American rattlesnake)
| 8,732 | 138 | 15,969 |
3D-structure;Blood coagulation cascade inhibiting toxin;Calcium;Direct protein sequencing;Disulfide bond;Hemostasis impairing toxin;Hydrolase;Ion channel impairing toxin;Lipid degradation;Lipid metabolism;Metal-binding;Neurotoxin;Pharmaceutical;Presynaptic neurotoxin;Secreted;Signal;Toxin
|
GO:0005509; GO:0005543; GO:0005576; GO:0006644; GO:0016042; GO:0042130; GO:0047498; GO:0050482; GO:0090729; GO:0099106
|
Evidence at protein level
| 5 |
SUBCELLULAR LOCATION: Secreted.
|
SIGNAL 1..16; /evidence="ECO:0000269|PubMed:15032748, ECO:0000269|PubMed:8033889"
| null |
PF00068;
|
IPR001211;IPR033112;IPR016090;IPR036444;IPR033113;
|
2QOG;
|
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Viperidae (family), Crotalinae (subfamily), Crotalus (genus), Crotalus durissus (species)
| null | true |
Crotalus durissus
| 17 |
row_366
| false | null |
1,445 |
P0CAS4
|
SLVQFEKMIKEETGKNAVPFYAFYGCYCGWGGRGRPKDATDRCCIVHDCCYEKLVKCNTKWDFYRYSLRSGYFQCGKGTWCEQQICECDRVAAECLRRSLSTYRYGKMIYPDSRCREPSETC
|
Basic phospholipase A2 Cdr-13 (svPLA2) (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase)
|
Crotalus durissus ruruima (South American rattlesnake) (Mt. Roraima rattlesnake)
| 221,570 | 122 | 14,297 |
Calcium;Direct protein sequencing;Disulfide bond;Hydrolase;Lipid degradation;Lipid metabolism;Metal-binding;Myotoxin;Neurotoxin;Secreted;Toxin
|
GO:0005509; GO:0005543; GO:0005576; GO:0006644; GO:0016042; GO:0042130; GO:0047498; GO:0050482; GO:0090729
|
Evidence at protein level
| 4 |
SUBCELLULAR LOCATION: Secreted.
| null | null |
PF00068;
|
IPR001211;IPR033112;IPR016090;IPR036444;IPR033113;
| null |
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Viperidae (family), Crotalinae (subfamily), Crotalus (genus), Crotalus durissus (species)
| null | true |
Crotalus durissus
| 18 |
row_1384
| false | null |
94 |
C0HM96
|
QVMPFMEVYERSVCQTREMLVSILDEYPSEVAHLFRPSCVTVLRCGGCCTEESLTCTATGKRSVGREIMRVDPRQGTSKIEVMQFTEHTECECRPGSTVNNGKRKKNPKEGEPR
|
Snake venom vascular endothelial growth factor (svVEGF) (VEGF-F)
|
Crotalus durissus terrificus (South American rattlesnake)
| 8,732 | 114 | 12,903 |
Direct protein sequencing;Disulfide bond;Growth factor;Pharmaceutical;Pyrrolidone carboxylic acid;Secreted;Toxin
|
GO:0001666; GO:0001938; GO:0002040; GO:0005172; GO:0005615; GO:0008083; GO:0016020; GO:0038084; GO:0042056; GO:0045766; GO:0048010; GO:0050930; GO:0060754; GO:0090729
|
Evidence at protein level
| 5 |
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:37624240}.
| null | null |
PF00341;
|
IPR029034;IPR023581;IPR000072;IPR050507;
| null |
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Viperidae (family), Crotalinae (subfamily), Crotalus (genus), Crotalus durissus (species)
| null | true |
Crotalus durissus
| 19 |
row_88
| false | null |
2,641 |
C0HK19
|
WDKDIMLIRLNKPVSYSEHIAPLSLPSSPPIVGSVCRPHCANINLLDYEVCRTAHPQFRLPATSRILCAGVLEGGIDTCHR
|
Thrombin-like enzyme collinein-3 (SVTLE collinein-3) (EC 3.4.21.-) (Fibrinogen-clotting enzyme) (Snake venom serine protease) (SVSP)
|
Crotalus durissus collilineatus (Brazilian rattlesnake)
| 221,569 | 81 | 8,964 |
Direct protein sequencing;Disulfide bond;Fibrinogenolytic toxin;Hemostasis impairing toxin;Hydrolase;Protease;Secreted;Serine protease;Toxin
|
GO:0004252; GO:0005576; GO:0006508; GO:0030141; GO:0090729
|
Evidence at protein level
| 3 |
SUBCELLULAR LOCATION: Secreted {ECO:0000269|Ref.1}.
| null | null |
PF00089;
|
IPR009003;IPR043504;IPR001254;
| null |
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Viperidae (family), Crotalinae (subfamily), Crotalus (genus), Crotalus durissus (species)
| null | true |
Crotalus durissus
| 20 |
row_2553
| false | null |
4,165 |
P68521
|
AGEECDCGSPANPCCDAATCKLRPGAQCADGLCCDQCRFIKKGTVCRPARGDWNDDTCTGQSADCPRNGLYG
|
Disintegrin durissin (Platelet aggregation activation inhibitor)
|
Crotalus durissus durissus (Central American rattlesnake)
| 31,150 | 72 | 7,521 |
Cell adhesion impairing toxin;Direct protein sequencing;Disulfide bond;Hemostasis impairing toxin;Platelet aggregation inhibiting toxin;Secreted;Toxin
|
GO:0005576; GO:0005886; GO:0090729
|
Evidence at protein level
| 3 |
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:8419314}.
| null | null |
PF00200;
|
IPR018358;IPR001762;IPR036436;
| null |
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Viperidae (family), Crotalinae (subfamily), Crotalus (genus), Crotalus durissus (species)
| null | true |
Crotalus durissus
| 21 |
row_4000
| false | null |
790 |
Q9PWF3
|
MKILYLLFAFLFLAFLSEPGNAYKQCHKKGGHCFPKEKICLPPSSDFGKMDCRWRWKCCKKGSGK
|
Crotamine (Crt) (Myotoxin)
|
Crotalus durissus terrificus (South American rattlesnake)
| 8,732 | 65 | 7,519 |
3D-structure;Antibiotic;Antimicrobial;Direct protein sequencing;Disulfide bond;Fungicide;Ion channel impairing toxin;Myotoxin;Neurotoxin;Pharmaceutical;Potassium channel impairing toxin;Secreted;Signal;Toxin;Voltage-gated potassium channel impairing toxin
|
GO:0005576; GO:0015459; GO:0031640; GO:0042742; GO:0044564; GO:0050832; GO:0090729
|
Evidence at protein level
| 5 |
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:1176086}.
|
SIGNAL 1..22; /evidence="ECO:0000269|PubMed:1176086"
| null |
PF00819;
|
IPR023355;IPR000881;
|
1H5O;1Z99;
|
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Viperidae (family), Crotalinae (subfamily), Crotalus (genus), Crotalus durissus (species)
|
CRO2 CRT-P1
| true |
Crotalus durissus
| 22 |
row_740
| false | null |
2,640 |
C0HK18
|
GGDECNINEHRSPQETLPDVPHCANINLLDYEVCRTAHPQFRLPATSRTLCAGILEGGKDTCHR
|
Thrombin-like enzyme collinein-4 (SVTLE collinein-4) (EC 3.4.21.-) (Fibrinogen-clotting enzyme) (Snake venom serine protease) (SVSP)
|
Crotalus durissus collilineatus (Brazilian rattlesnake)
| 221,569 | 64 | 7,072 |
Direct protein sequencing;Disulfide bond;Fibrinogenolytic toxin;Hemostasis impairing toxin;Hydrolase;Protease;Secreted;Serine protease;Toxin
|
GO:0005576; GO:0006508; GO:0008236; GO:0090729
|
Evidence at protein level
| 3 |
SUBCELLULAR LOCATION: Secreted {ECO:0000269|Ref.1}.
| null | null | null |
IPR009003;IPR043504;
| null |
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Viperidae (family), Crotalinae (subfamily), Crotalus (genus), Crotalus durissus (species)
| null | true |
Crotalus durissus
| 23 |
row_2552
| false | null |
6,725 |
P24332
|
KILYLLFAFLFLAFLSEPGNAYKRCHIKGGHCFPKEKICIPPSSDFGKMDCPWRRKSLKKGSGK
|
Myotoxin-2 (Crotamine-2)
|
Crotalus durissus terrificus (South American rattlesnake)
| 8,732 | 64 | 7,306 |
Antimicrobial;Disulfide bond;Ion channel impairing toxin;Myotoxin;Neurotoxin;Potassium channel impairing toxin;Secreted;Signal;Toxin;Voltage-gated potassium channel impairing toxin
|
GO:0005576; GO:0015459; GO:0044564; GO:0090729
|
Evidence at transcript level
| 2 |
SUBCELLULAR LOCATION: Secreted {ECO:0000305|PubMed:2389256}.
|
SIGNAL <1..21; /evidence="ECO:0000250|UniProtKB:Q9PWF3"
| null |
PF00819;
|
IPR023355;IPR000881;
| null |
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Viperidae (family), Crotalinae (subfamily), Crotalus (genus), Crotalus durissus (species)
| null | true |
Crotalus durissus
| 24 |
row_6473
| false | null |
1,402 |
P0C2D2
|
ADDRNPLEQCFRETDYEEFLEIARNNLKATSNPKHVVIVGAGMAGLSAAYVLSGGGHQVTV
|
L-amino-acid oxidase (Casca LAO) (LAAO) (EC 1.4.3.2)
|
Crotalus durissus cascavella (Northeastern Brazilian rattlesnake)
| 184,540 | 61 | 6,561 |
Antibiotic;Antimicrobial;Apoptosis;Cytolysis;Direct protein sequencing;Disulfide bond;FAD;Flavoprotein;Glycoprotein;Hemolysis;Hemostasis impairing toxin;Oxidoreductase;Platelet aggregation activating toxin;Secreted;Toxin
|
GO:0001716; GO:0005576; GO:0006915; GO:0031640; GO:0042742; GO:0090729
|
Evidence at protein level
| 4 |
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:16307769}.
| null | null |
PF00890;
|
IPR003953;IPR036188;
| null |
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Viperidae (family), Crotalinae (subfamily), Crotalus (genus), Crotalus durissus (species)
| null | true |
Crotalus durissus
| 25 |
row_1341
| false | null |
6,727 |
P24334
|
FLSEPGNAYKQCHKKGGHCFPKEKICIPPSSDFGKMDCRWRWKCCKKRSGK
|
Myotoxin-4 (Crotamine-4)
|
Crotalus durissus terrificus (South American rattlesnake)
| 8,732 | 51 | 5,933 |
Antimicrobial;Disulfide bond;Ion channel impairing toxin;Myotoxin;Neurotoxin;Potassium channel impairing toxin;Secreted;Signal;Toxin;Voltage-gated potassium channel impairing toxin
|
GO:0005576; GO:0015459; GO:0044564; GO:0090729
|
Evidence at transcript level
| 2 |
SUBCELLULAR LOCATION: Secreted {ECO:0000305|PubMed:2389256}.
|
SIGNAL <1..8; /evidence="ECO:0000250|UniProtKB:Q9PWF3"
| null |
PF00819;
|
IPR023355;IPR000881;
| null |
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Viperidae (family), Crotalinae (subfamily), Crotalus (genus), Crotalus durissus (species)
| null | true |
Crotalus durissus
| 26 |
row_6475
| false | null |
1,509 |
P0DKY5
|
VVGGDECNINEHRFLVALYANSSLLCGGTLINQEWVLIAAHCDR
|
Thrombin-like enzyme F202 (SVTLE) (EC 3.4.21.-) (Fibrinogen-clotting enzyme) (Snake venom serine protease) (SVSP)
|
Crotalus durissus cascavella (Northeastern Brazilian rattlesnake)
| 184,540 | 44 | 4,815 |
Blood coagulation cascade activating toxin;Direct protein sequencing;Disulfide bond;Fibrinogenolytic toxin;Hemostasis impairing toxin;Hydrolase;Platelet aggregation activating toxin;Protease;Secreted;Serine protease;Toxin
|
GO:0004252; GO:0005615; GO:0006508; GO:0090729
|
Evidence at protein level
| 4 |
SUBCELLULAR LOCATION: Secreted.
| null | null |
PF00089;
|
IPR009003;IPR043504;IPR050127;IPR001254;
| null |
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Viperidae (family), Crotalinae (subfamily), Crotalus (genus), Crotalus durissus (species)
| null | true |
Crotalus durissus
| 27 |
row_1445
| false | null |
1,927 |
P86193
|
YKRCHIKGGHCFPKEKLICIPPSSDIGKMDCPWKRKCCKKRS
|
Crotamine-IV-2
|
Crotalus durissus cumanensis (South American rattlesnake)
| 184,542 | 42 | 4,907 |
Antimicrobial;Direct protein sequencing;Disulfide bond;Ion channel impairing toxin;Myotoxin;Neurotoxin;Potassium channel impairing toxin;Secreted;Toxin;Voltage-gated potassium channel impairing toxin
|
GO:0005576; GO:0015459; GO:0044521; GO:0044522; GO:0044564; GO:0090729
|
Evidence at protein level
| 4 |
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:17828447}.
| null | null |
PF00819;
|
IPR023355;IPR000881;
| null |
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Viperidae (family), Crotalinae (subfamily), Crotalus (genus), Crotalus durissus (species)
| null | true |
Crotalus durissus
| 28 |
row_1848
| false | null |
3,478 |
P0DKY6
|
VSTSRGSQGCFGLKLDRIGAASGLGCWRRIVDS
|
Natriuretic peptide NP2 (NP2_Casca)
|
Crotalus durissus cascavella (Northeastern Brazilian rattlesnake)
| 184,540 | 33 | 3,454 |
Direct protein sequencing;Disulfide bond;Hypotensive agent;Secreted;Toxin;Vasoactive;Vasodilator
|
GO:0005179; GO:0005576; GO:0008217; GO:0042311; GO:0090729
|
Evidence at protein level
| 3 |
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:18835291}.
| null | null |
PF00212;
|
IPR000663;IPR030480;
| null |
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Viperidae (family), Crotalinae (subfamily), Crotalus (genus), Crotalus durissus (species)
| null | true |
Crotalus durissus
| 29 |
row_3356
| false | null |
5,590 |
C0HLL1
|
ARIECDCGSIENPCCYATTCKLRPGSQCAEGM
|
Zinc metalloproteinase/disintegrin-like CdtV1 (SVMP) [Cleaved into: Zinc metalloproteinase/disintegrin-like CdtV2; Zinc metalloproteinase/disintegrin-like CdtV3]
|
Crotalus durissus terrificus (South American rattlesnake)
| 8,732 | 32 | 3,411 |
Direct protein sequencing;Disulfide bond;Hydrolase;Secreted;Toxin
|
GO:0005576; GO:0016787; GO:0090729
|
Evidence at protein level
| 2 |
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:30270628}.
| null | null | null |
IPR001762;IPR036436;
| null |
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Viperidae (family), Crotalinae (subfamily), Crotalus (genus), Crotalus durissus (species)
| null | true |
Crotalus durissus
| 30 |
row_5350
| false | null |
2,619 |
C0HJR6
|
TALPQLRLPATSRILCAGVLEGGIDTCNR
|
Thrombin-like enzyme collinein-2 (SVTLE collinein-2) (EC 3.4.21.-) (Fibrinogen-clotting enzyme) (Snake venom serine protease) (SVSP)
|
Crotalus durissus collilineatus (Brazilian rattlesnake)
| 221,569 | 29 | 3,040 |
Direct protein sequencing;Disulfide bond;Hydrolase;Protease;Secreted;Serine protease;Toxin
|
GO:0005576; GO:0006508; GO:0008236; GO:0090729
|
Evidence at protein level
| 3 |
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:26227411}.
| null | null | null | null | null |
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Viperidae (family), Crotalinae (subfamily), Crotalus (genus), Crotalus durissus (species)
| null | true |
Crotalus durissus
| 31 |
row_2531
| false | null |
1,494 |
P0DJN1
|
HLLQFNKMIKFETRKNAIPFYAF
|
Basic phospholipase A2 CB1 (svPLA2) (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase)
|
Crotalus durissus cumanensis (South American rattlesnake)
| 184,542 | 23 | 2,857 |
Calcium;Direct protein sequencing;Disulfide bond;Hydrolase;Lipid degradation;Lipid metabolism;Metal-binding;Neurotoxin;Presynaptic neurotoxin;Secreted;Toxin
|
GO:0004623; GO:0005576; GO:0016042; GO:0046872; GO:0090729
|
Evidence at protein level
| 4 |
SUBCELLULAR LOCATION: Secreted.
| null | null | null | null | null |
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Viperidae (family), Crotalinae (subfamily), Crotalus (genus), Crotalus durissus (species)
| null | true |
Crotalus durissus
| 32 |
row_1431
| false | null |
1,443 |
P0CAS1
|
SLVQFEKMIKEVAGKNGVPWY
|
Phospholipase A2 crotoxin basic chain (CB) (svPLA2) (EC 3.1.1.4) (Cdcum6) (Phosphatidylcholine 2-acylhydrolase)
|
Crotalus durissus cumanensis (South American rattlesnake)
| 184,542 | 21 | 2,424 |
Blood coagulation cascade inhibiting toxin;Calcium;Direct protein sequencing;Hemostasis impairing toxin;Hydrolase;Lipid degradation;Lipid metabolism;Metal-binding;Neurotoxin;Presynaptic neurotoxin;Secreted;Toxin
|
GO:0004623; GO:0005576; GO:0016042; GO:0046872; GO:0090729
|
Evidence at protein level
| 4 |
SUBCELLULAR LOCATION: Secreted.
| null | null | null | null | null |
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Viperidae (family), Crotalinae (subfamily), Crotalus (genus), Crotalus durissus (species)
| null | true |
Crotalus durissus
| 33 |
row_1382
| false | null |
1,508 |
P0DKX3
|
VIGGDICNINEHNFLVALYE
|
Thrombin-like enzyme Cdc SII (SVTLE) (EC 3.4.21.-) (Fibrinogen-clotting enzyme) (Snake venom serine protease) (SVSP)
|
Crotalus durissus cumanensis (South American rattlesnake)
| 184,542 | 20 | 2,234 |
Blood coagulation cascade activating toxin;Direct protein sequencing;Disulfide bond;Fibrinogenolytic toxin;Hemostasis impairing toxin;Hydrolase;Protease;Secreted;Serine protease;Toxin
|
GO:0005576; GO:0006508; GO:0008236; GO:0090729
|
Evidence at protein level
| 4 |
SUBCELLULAR LOCATION: Secreted.
| null | null | null | null | null |
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Viperidae (family), Crotalinae (subfamily), Crotalus (genus), Crotalus durissus (species)
| null | true |
Crotalus durissus
| 34 |
row_1444
| false | null |
1,209 |
C9E1S0
|
MIQVLLVTLCLAAFPYQGSSIILDSGNVNDYEVVYPRKVTALPKGAVQPKYEDTMQYEFKVNGEPVVLHLEKNKGLFSEDYSETHYSPDGREITTYPSIEDHCYYRGRIQNDADSTASISACNGLKGHFKLQGEMYLIEPLKLPDSEAHAVYKYENIEKEDEAPKMCGVTQTNWKSDEPIKKASQLVVTPEEQRYLNTKKYIELVIVADNVMVKKYTSNSTAIRTRIYACVNTLNLIYRAFNIYIALIGLEIWSNRDLINVQSASSVTLDLFGTWRETVLLRHKRHDNAQLLTGINFDGDTVGLAYVGSMCDPKRSAGIIQDHNKLDVMVAIAMAHELGHDLGINHDGNQCNCGGNPCIMSATLNFEPVYRFSDCSRDEHWRYLIDNRPPCILNKPSITDIVSPPVCGNYFVEVGEECDCGLPAHCQNPCCDAATCKLRPETQCEDGECCEQCQFTRAGTECRAARSECDIAESCTGQSAECPTDDFQRNGQPCLNNNGYCYNGTCPILTNQCISFFGSSATVAPDVCFDFNLQGQGNFYCRRERARIFPCAPQDKKCGRLFCVKGPIGNTISCQSTSSQSDLDIGMVDLGTKCGDGRVCNSNRQCVDVNTAY
|
Zinc metalloproteinase-disintegrin-like VMP-III (AplVMP-III) (EC 3.4.24.-) (Snake venom metalloproteinase) (SVMP)
|
Agkistrodon piscivorus leucostoma (Western cottonmouth) (Acontias leucostoma)
| 459,671 | 613 | 68,212 |
Calcium;Cell adhesion impairing toxin;Disulfide bond;Glycoprotein;Hemostasis impairing toxin;Hydrolase;Metal-binding;Metalloprotease;Protease;Secreted;Signal;Toxin;Zinc;Zymogen
|
GO:0004222; GO:0005576; GO:0005886; GO:0006508; GO:0046872; GO:0090729
|
Evidence at transcript level
| 4 |
SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
|
SIGNAL 1..20; /evidence="ECO:0000255"
| null |
PF08516;PF00200;PF01562;PF01421;
|
IPR006586;IPR018358;IPR001762;IPR036436;IPR024079;IPR001590;IPR002870;IPR034027;
| null |
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Viperidae (family), Crotalinae (subfamily), Agkistrodon (genus), Agkistrodon piscivorus (species)
| null | true |
Agkistrodon piscivorus
| 0 |
row_1153
| false | null |
714 |
Q805F4
|
MIQVLLVTLCLAAFPYQGNSIILESGNVNDYEVLYPQKVTALPKGAVQPKYEDTMQYEFKVNGEPVVLHLEKNKGLFSKDYSETHYSSDGRKITTNPPVEDHCYYHGRIQNDADSTASISACNGLKGHFKLQGETYLIEPLKLSDSEAHAVYKYENVEKEDEAPKMCGVTQTNWKSDKPIKKASQLNLTPEQQRFPQRYIELVVVADHRMFTKYNGNLNTIRIWVHELVNTMNVFYRPLNIHVSLTDLEVWSDQDLINVQPAAADTLEAFGDWRETVLLNRISHDNAQLLTAIELDGETIGLANRGTMCDPKLSTGIVQDHSAINLWVAVTMAHEMGHNLGISHDGNQCHCDANSCIMSEELRQQLSFEFSDCSQNQYQTFLTDHNPQCMLNEPLRTDIVSTPVSGNELWETGEESDFDAPANPCCDAATCKLTPGSQCAEGLCCDQCKFMKEGTVCHRAKGDDLDDYCNGISAGCPRNPFHA
|
Zinc metalloproteinase/disintegrin [Cleaved into: Snake venom metalloproteinase (SVMP) (EC 3.4.24.-); Disintegrin piscivostatin-beta (PVS-beta)]
|
Agkistrodon piscivorus piscivorus (Eastern cottonmouth)
| 8,716 | 483 | 54,073 |
Calcium;Cell adhesion impairing toxin;Direct protein sequencing;Disulfide bond;Hemostasis impairing toxin;Hydrolase;Metal-binding;Metalloprotease;Platelet aggregation inhibiting toxin;Protease;Secreted;Signal;Toxin;Zinc;Zymogen
|
GO:0004222; GO:0005576; GO:0005886; GO:0006508; GO:0046872; GO:0090729
|
Evidence at protein level
| 5 |
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:11530017}.
|
SIGNAL 1..20; /evidence="ECO:0000255"
| null |
PF00200;PF01562;PF01421;
|
IPR001762;IPR036436;IPR024079;IPR001590;IPR002870;IPR034027;
| null |
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Viperidae (family), Crotalinae (subfamily), Agkistrodon (genus), Agkistrodon piscivorus (species)
| null | true |
Agkistrodon piscivorus
| 1 |
row_668
| false | null |
967 |
B7U492
|
MIQVLLVTICLAAFPYQGSSIILESGNVNDYEIVYPRKVTPVPRGAVQPKYEDAMQYELKVNGEPVVLHLEKNKGLFSEDYSETHYSPDGREITTYPLVEDHCYYHGRIENDADSTASISTCNGLKGHFKLQGEMYLIEPLELSDSEAHAVYKYENVEKEDEAPKMCGVTQNWESYEPTKKAFQLNLTPEQQGFPQRYVELVIIADHRMYMKYKRDSNKITQWVHQMVNTINEIYRPLNIQFALVGLEIWSNQDLITVTSVSDDTLISFANWRETVLLRRKSHDNAQLLTAIVFDEGIIGRAPLAGMCDPNRSVGTVQDHSKINFRVAIIMAHEIGHNLGMGHDDNSCTCGGYSCIMLPRLSKQPSKLFSDCSKKDYLTFLKVKNPQCILNKPLRTDTVSTPVSGNELLEA
|
Snake venom metalloproteinase VMP1 (AplVMP-I) (AplVMP1) (SVMP) (EC 3.4.24.-)
|
Agkistrodon piscivorus leucostoma (Western cottonmouth) (Acontias leucostoma)
| 459,671 | 411 | 46,583 |
Calcium;Disulfide bond;Fibrinogenolytic toxin;Fibrinolytic toxin;Glycoprotein;Hemostasis impairing toxin;Hydrolase;Metal-binding;Metalloprotease;Protease;Secreted;Signal;Toxin;Zinc;Zymogen
|
GO:0004222; GO:0005576; GO:0005886; GO:0006508; GO:0046872; GO:0090729
|
Evidence at transcript level
| 4 |
SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
|
SIGNAL 1..20; /evidence="ECO:0000255"
| null |
PF01562;PF01421;
|
IPR024079;IPR001590;IPR002870;IPR034027;
| null |
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Viperidae (family), Crotalinae (subfamily), Agkistrodon (genus), Agkistrodon piscivorus (species)
| null | true |
Agkistrodon piscivorus
| 2 |
row_912
| false | null |
2,918 |
E5L0E6
|
MVLIRVLANLLILHLSYAQKSSELVIGGDECNINEHRFLALVYANGSLCGGTLINQEWVLTARHCDRGNMRIYLGMHNLKVLNKDALRRFPKEKYFCLNIRNDTIWDKDIMLIRLNRPVRNSAHIAPLSLPSNPPSVGSVCRVMGWGTITSPNATLPDVPHCANINILDYAVCQAAYRGLAATTLCSGILEGGKDTCKGDSGGPLICNGQFQGILSVGGNPCAQPRKPGVYTKVFDYTDWIQSIISGNTDAACPP
|
Protein C activator (APL-C) (EC 3.4.21.-) (Snake venom serine protease) (SVSP)
|
Agkistrodon piscivorus leucostoma (Western cottonmouth) (Acontias leucostoma)
| 459,671 | 255 | 27,811 |
Blood coagulation cascade inhibiting toxin;Disulfide bond;Glycoprotein;Hemostasis impairing toxin;Hydrolase;Protease;Secreted;Serine protease;Signal;Toxin;Zymogen
|
GO:0004252; GO:0005576; GO:0006508; GO:0030141; GO:0090729
|
Evidence at transcript level
| 3 |
SUBCELLULAR LOCATION: Secreted {ECO:0000250|UniProtKB:P09872}.
|
SIGNAL 1..18; /evidence="ECO:0000255"
| null |
PF00089;
|
IPR009003;IPR043504;IPR001314;IPR001254;IPR033116;
| null |
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Viperidae (family), Crotalinae (subfamily), Agkistrodon (genus), Agkistrodon piscivorus (species)
| null | true |
Agkistrodon piscivorus
| 3 |
row_2822
| false | null |
4,728 |
Q7ZTA0
|
MIAFIVLPILAAVLQQSSGSVDFDSESPRKPEIQNQIVDLHNSLRRSVNPTASNMLKMEWYPEAAANAERWAYRCIESHSPRNSRVLGGIKCGENIYMSSIPIKWTEIIHAWHGENKNFKYGIGADPPNAVIGHFTQIVWYKSYLVGCAAAYCPSSEYSYFYVCQYCPAGNIIGKIATPYKSGPPCGDCPSACVNGLCTNPCTKEDKYTNCKSLVQQYGCQDKQMQSECSAICFCQNKII
|
Cysteine-rich venom protein piscivorin
|
Agkistrodon piscivorus piscivorus (Eastern cottonmouth)
| 8,716 | 240 | 26,682 |
Calcium channel impairing toxin;Direct protein sequencing;Disulfide bond;Ion channel impairing toxin;Neurotoxin;Secreted;Signal;Toxin
|
GO:0005246; GO:0005576; GO:0090729
|
Evidence at protein level
| 3 |
SUBCELLULAR LOCATION: Secreted.
|
SIGNAL 1..19; /evidence="ECO:0000269|PubMed:12646276"
| null |
PF00188;PF08562;
|
IPR018244;IPR014044;IPR035940;IPR042076;IPR001283;IPR013871;IPR034117;IPR003582;IPR002413;
| null |
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Viperidae (family), Crotalinae (subfamily), Agkistrodon (genus), Agkistrodon piscivorus (species)
| null | true |
Agkistrodon piscivorus
| 4 |
row_4504
| false | null |
24 |
A0A411EZW9
|
MRTLWIMAVLLLGVEGDLMQFETLIMKIAKRSGMFWYSAYGCYCGWGGQGRPQDATDRCCFVHDCCYGKVTGCDPKLDSYTYSVENGDVVCGGNDPCKKEICECDRAAAICFRDNKVTYDNKYWRFPPQNCKEESEPC
|
Acidic phospholipase A2 AplTX-I (svPLA2) (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase)
|
Agkistrodon piscivorus leucostoma (Western cottonmouth) (Acontias leucostoma)
| 459,671 | 138 | 15,685 |
Calcium;Direct protein sequencing;Disulfide bond;Hemostasis impairing toxin;Hydrolase;Lipid degradation;Lipid metabolism;Metal-binding;Neurotoxin;Platelet aggregation inhibiting toxin;Presynaptic neurotoxin;Secreted;Signal;Toxin
|
GO:0005509; GO:0005543; GO:0005576; GO:0006644; GO:0016042; GO:0042130; GO:0047498; GO:0050482; GO:0090729
|
Evidence at protein level
| 5 |
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:28063838}.
|
SIGNAL 1..16; /evidence="ECO:0000269|PubMed:28063838"
| null |
PF00068;
|
IPR001211;IPR033112;IPR016090;IPR036444;IPR033113;
| null |
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Viperidae (family), Crotalinae (subfamily), Agkistrodon (genus), Agkistrodon piscivorus (species)
| null | true |
Agkistrodon piscivorus
| 5 |
row_21
| false | null |
993 |
C0HKC2
|
MRTLWIVALLLVGVEGSVLELGKMILQETGKNAITSYGSYGCNCGWGHRGQPKDATDRCCFVHKCCYKKLTDCNHKTDRYSYSWKNKAIICEEKNPCLKEMCECDKAVAICLRENLDTYNKKYKAYFKLKCKKPDTC
|
Basic phospholipase A2 homolog APL-K49 (svPLA2 homolog) (AplP2)
|
Agkistrodon piscivorus leucostoma (Western cottonmouth) (Acontias leucostoma)
| 459,671 | 137 | 15,713 |
Direct protein sequencing;Disulfide bond;Myotoxin;Secreted;Signal;Toxin
|
GO:0005509; GO:0005543; GO:0005576; GO:0006644; GO:0016042; GO:0042130; GO:0047498; GO:0050482; GO:0090729
|
Evidence at protein level
| 4 |
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:28633930}.
|
SIGNAL 1..16; /evidence="ECO:0000269|PubMed:28633930"
| null |
PF00068;
|
IPR001211;IPR033112;IPR016090;IPR036444;IPR033113;
| null |
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Viperidae (family), Crotalinae (subfamily), Agkistrodon (genus), Agkistrodon piscivorus (species)
| null | true |
Agkistrodon piscivorus
| 6 |
row_938
| false | null |
2,711 |
C0K3N2
|
MAAYLLAVAILFCIQGWPSGTVQGQAMPFMEVYTRSACQTRETLVSILEEHPHEISHLFKPSCVTVLRCGGCCSDESLTCTSTGKRSVGREIMRVDPHKETSKIEVMQFTEHTDCECRPQSASG
|
Snake venom vascular endothelial growth factor toxin apiscin (svVEGF) (VEGF-F)
|
Agkistrodon piscivorus piscivorus (Eastern cottonmouth)
| 8,716 | 124 | 13,700 |
Disulfide bond;Growth factor;Pyrrolidone carboxylic acid;Secreted;Signal;Toxin
|
GO:0001666; GO:0001938; GO:0002040; GO:0005172; GO:0005615; GO:0008083; GO:0016020; GO:0038084; GO:0042056; GO:0045766; GO:0048010; GO:0050930; GO:0060754; GO:0090729
|
Evidence at transcript level
| 3 |
SUBCELLULAR LOCATION: Secreted {ECO:0000305|PubMed:19208624}.
|
SIGNAL 1..24; /evidence="ECO:0000255"
| null |
PF00341;
|
IPR029034;IPR023581;IPR000072;IPR050507;
| null |
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Viperidae (family), Crotalinae (subfamily), Agkistrodon (genus), Agkistrodon piscivorus (species)
| null | true |
Agkistrodon piscivorus
| 7 |
row_2620
| false | null |
2,744 |
C9E1S2
|
MIQVLLVTICLAVFPYQGSSIILESGNVNDYEVVYPRKITPLPKGAVQPKNPCCDAATCKLTPGAQCAEGLCCDQCKFIKAGKICRRARGDNPDYRCTGQSGDCPRKHFYA
|
Disintegrin subunit alpha
|
Agkistrodon piscivorus leucostoma (Western cottonmouth) (Acontias leucostoma)
| 459,671 | 111 | 12,103 |
Cell adhesion impairing toxin;Disulfide bond;Secreted;Signal;Toxin
|
GO:0005576; GO:0005886; GO:0090729
|
Evidence at transcript level
| 3 |
SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
|
SIGNAL 1..20; /evidence="ECO:0000255"
| null |
PF00200;
|
IPR018358;IPR001762;IPR036436;
| null |
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Viperidae (family), Crotalinae (subfamily), Agkistrodon (genus), Agkistrodon piscivorus (species)
| null | true |
Agkistrodon piscivorus
| 8 |
row_2652
| false | null |
1,018 |
C0HM79
|
NLFQFEKLIKKSGMLWYSAYGCYCGWGGQGRPKDATDRCCFVHDCCYGKVTGCNPKCGGTNPCKKQICECDRAAAICFRDNLKTYDSKTYWKYPK
|
Basic phospholipase A2 (svPLA2) (EC 3.1.1.4)
|
Agkistrodon piscivorus leucostoma (Western cottonmouth) (Acontias leucostoma)
| 459,671 | 95 | 10,838 |
Calcium;Direct protein sequencing;Disulfide bond;Hydrolase;Lipid degradation;Lipid metabolism;Lipoprotein;Metal-binding;Palmitate;Secreted;Toxin
|
GO:0005509; GO:0005543; GO:0005576; GO:0006644; GO:0016042; GO:0042130; GO:0047498; GO:0050482; GO:0090729
|
Evidence at protein level
| 4 |
SUBCELLULAR LOCATION: Secreted {ECO:0000269|Ref.1}.
| null | null |
PF00068;
|
IPR001211;IPR033112;IPR016090;IPR036444;IPR033113;
| null |
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Viperidae (family), Crotalinae (subfamily), Agkistrodon (genus), Agkistrodon piscivorus (species)
| null | true |
Agkistrodon piscivorus
| 9 |
row_963
| false | null |
3,867 |
P16338
|
EAGEECDCGSPENPCCDAATCKLRPGAQCAEGLCCDQCKFMKEGTVCRARGDDVNDYCNGISAGCPRNPFH
|
Disintegrin applaggin (Applagin) (Platelet aggregation activation inhibitor)
|
Agkistrodon piscivorus piscivorus (Eastern cottonmouth)
| 8,716 | 71 | 7,522 |
Cell adhesion impairing toxin;Direct protein sequencing;Disulfide bond;Hemostasis impairing toxin;Platelet aggregation inhibiting toxin;Secreted;Toxin
|
GO:0005576; GO:0090729
|
Evidence at protein level
| 3 |
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:2510158}.
| null | null |
PF00200;
|
IPR018358;IPR001762;IPR036436;
| null |
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Viperidae (family), Crotalinae (subfamily), Agkistrodon (genus), Agkistrodon piscivorus (species)
| null | true |
Agkistrodon piscivorus
| 10 |
row_3715
| false | null |
3,987 |
P39410
|
MSELTDLLLQGPRSAPELRQRLAISQATFSRLVAREDRVIRFGKARATRYALLRPYRGIERIPVWRVDDTGKAHKFADIRLCWPQGSCLVTGADGDEQWFDGLPWYLTDLRPQGFLGRAWGRKLAAQLNLTDDIRLWQEEDVLYALTVFNGEYTGGWLVGEGNYQRWITAQHPAEIPLDQKLTHYEQLASDALAGEIVGSSAGGEQPKFTYYAQTPSGNKHVLVKFTVPQQTAVSQRWGDLLIAESIAAQILRDGGIHAIESTVLVTSNRQVFLEAERFDCKGNDGRLPIVSLEAVQSEFISSPGSWPQAMRRLCEQQLVTHQSVAQTEVIWAFGRLIANSDMHAGNLSFYLSEPPFALTPVYDMLPMVYAPNSAGMLRDAAIEVKFDLNVSKSAWLTAIPLAQQFWQTVARDPRISEAFRHIAQEMPEKIRQIEEKVARMGG
|
Toxin YjjJ (Putative DNA-binding transcriptional regulator YjjJ) (Putative serine/threonine kinase toxin YjjJ) (EC 2.-.-.-)
|
Escherichia coli (strain K12)
| 83,333 | 443 | 49,757 |
DNA-binding;Kinase;Reference proteome;Toxin;Transferase
|
GO:0003677; GO:0004674; GO:0005829; GO:0090729
|
Evidence at protein level
| 3 | null | null | null |
PF07804;
|
IPR012893;IPR052028;
| null |
cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Gammaproteobacteria (class), Enterobacterales (order), Enterobacteriaceae (family), Escherichia (genus), Escherichia coli (species)
|
yjjJ b4385 JW4348
| true |
Escherichia coli
| 0 |
row_3830
| false | null |
60 |
B3BM80
|
MVNATLSVVQKNSAFVGSATGELAARAIGMLYPGVKQSDLSEEQKQTISTLATVSAGLAGGLTGSSTASAAVGAQSGKNAVENNYLSTNQSLTFDKELSDCRKSGGNCQDIIDKWEKISDEQSAEIDQKLKDNPLEAQVIDKEVAKGGYDMTQRPGWLGNIGVEVMTSDEAKAYVQKWNGRDLTKIDVNSPEWTKFAVFASDPENQAMLVSGGLLVKDITKAAISFMSRNTATATVNASEVGMQWGQGNMKQGMPWEDYVGKSLPADARLPKNFKIFDYYDGATKTATSVKSIDTQTMAKLANPNQVYSSIKGNIDAAAKFKEYALSGRELTSSMISNREIQLAIPADTTKTQWAEINRAIEYGKSQGVKVTVTQVK
|
Deoxyribonuclease CdiA-o11 (DNase CdiA) (EC 3.1.-.-) (CdiA-o11-EC869) (Toxin CdiA)
|
Escherichia coli O157:H7 (strain EC869)
| 478,008 | 377 | 40,578 |
3D-structure;Hydrolase;Metal-binding;Nuclease;Target cell cytoplasm;Toxin;Virulence;Zinc
|
GO:0004530; GO:0046872; GO:0090729
|
Evidence at protein level
| 5 |
SUBCELLULAR LOCATION: Target cell, target cell cytoplasm {ECO:0000305|PubMed:25174572}. Note=Toxin translocation into the target cell depends on the proton motive force of the target cell, but not on tolA or tonB. {ECO:0000269|PubMed:25174572}.
| null | null |
PF21111;PF21483;PF04829;
|
IPR033799;IPR048745;IPR006914;
|
4G6U;4ZQW;
|
cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Gammaproteobacteria (class), Enterobacterales (order), Enterobacteriaceae (family), Escherichia (genus), Escherichia coli (species), Escherichia coli O157:H7 (serotype)
|
cdiA4 cdiA-CTo11 ECH7EC869_5883
| true |
Escherichia coli
| 1 |
row_54
| false | null |
70 |
B7UI21
|
MLSSLNVLQSSFRGKTALSNSTLLQKVSFAGKEYSLEPIDERTPILFQWFEARPERYEKGEVPILNTKEHPYLSNIINAAKIENERIIGVLVDGNFTYEQKKEFLNLENEHQNIKIIYRADVDFSMYDKKLSDIYLENIHKQESYPASERDNYLLGLLREELKNIPEGKDSLIESYAEKREHTWFDFFRNLAILKAGSLFTETGKTGCHNISPCSGCIYLDADMIITDKLGVLYAPDGIAVHVDCNDEIKSLENGAIVVNRSNHPALLAGLDIMKSKVDAHPYYDGLGKGIKRHFNYSSLHNYNAFCDFIEFKHENIIPNTSMYTSSSW
|
Protein-arginine N-acetylglucosaminyltransferase NleB1 (Arginine GlcNAcyltransferase NleB1) (EC 2.4.1.-) (Non-LEE-encoded type III effector B1)
|
Escherichia coli O127:H6 (strain E2348/69 / EPEC)
| 574,521 | 329 | 37,627 |
3D-structure;Glycoprotein;Glycosyltransferase;Host cytoplasm;Manganese;Metal-binding;Reference proteome;Secreted;Toxin;Transferase;Virulence
|
GO:0005576; GO:0030145; GO:0030430; GO:0052041; GO:0085034; GO:0090729; GO:0106362
|
Evidence at protein level
| 5 |
SUBCELLULAR LOCATION: Secreted {ECO:0000250|UniProtKB:A0A482PDI9}. Host cytoplasm {ECO:0000269|PubMed:32432056}. Note=Secreted via the type III secretion system (T3SS). {ECO:0000250|UniProtKB:A0A482PDI9}.
| null | null |
PF24688;
| null |
6ACI;6E66;
|
cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Gammaproteobacteria (class), Enterobacterales (order), Enterobacteriaceae (family), Escherichia (genus), Escherichia coli (species), Escherichia coli O127:H6 (serotype)
|
nleB1 nleB E2348C_3231
| true |
Escherichia coli
| 2 |
row_64
| false | null |
2,321 |
A0A023YYV9
|
MLSPIRTTFHNSVNIVQSSPCQTVSFAGKEYELKVIDEKTPILFQWFEPNPERYKKDEVPIVNTKQHPYLDNVTNAARIESDRMIGIFVDGDFSVNQKTAFSKLERDFENVMIIYREDVDFSMYDRKLSDIYHDIICEQRLRTEDKRDEYLLNLLEKELREISKAQDSLISMYAKKRNHAWFDFFRNLALLKAGEIFRCTYNTKNHGISFGEGGIYLDMDMILTGKLGTIYAPDGISMHVDRRNDSVNIENSAIIVNRSNHPALLEGLSFMHSKVDAHPYYDGLGKGVKKYFNFTPLHNYNHFCDFIEFNHPNIIMNTSQYTCSSW
|
Protein-arginine N-acetylglucosaminyltransferase NleB2 (Arginine GlcNAcyltransferase NleB2) (EC 2.4.1.-)
|
Escherichia coli O145:H28 (strain RM12581)
| 1,248,823 | 326 | 38,010 |
3D-structure;Glycosyltransferase;Manganese;Metal-binding;Secreted;Toxin;Transferase;Virulence
|
GO:0005576; GO:0016757; GO:0043657; GO:0046872; GO:0090729
|
Evidence at protein level
| 3 |
SUBCELLULAR LOCATION: Secreted {ECO:0000250|UniProtKB:A0A482PDI9}. Host cell {ECO:0000250|UniProtKB:A0A482PDI9}. Note=Secreted via the type III secretion system (T3SS). {ECO:0000250|UniProtKB:A0A482PDI9}.
| null | null |
PF24688;
| null |
5H5Y;6AI4;
|
cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Gammaproteobacteria (class), Enterobacterales (order), Enterobacteriaceae (family), Escherichia (genus), Escherichia coli (species), Escherichia coli O145:H28 (serotype)
|
nleB2 ECRM12581_12505
| true |
Escherichia coli
| 3 |
row_2236
| false | null |
494 |
P77335
|
MTEIVADKTVEVVKNAIETADGALDLYNKYLDQVIPWQTFDETIKELSRFKQEYSQAASVLVGDIKTLLMDSQDKYFEATQTVYEWCGVATQLLAAYILLFDEYNEKKASAQKDILIKVLDDGITKLNEAQKSLLVSSQSFNNASGKLLALDSQLTNDFSEKSSYFQSQVDKIRKEAYAGAAAGVVAGPFGLIISYSIAAGVVEGKLIPELKNKLKSVQNFFTTLSNTVKQANKDIDAAKLKLTTEIAAIGEIKTETETTRFYVDYDDLMLSLLKEAAKKMINTCNEYQKRHGKKTLFEVPEV
|
Hemolysin E, chromosomal (Cytotoxin ClyA) (Hemolysis-inducing protein) (Latent pore-forming 34 kDa hemolysin) (Silent hemolysin SheA)
|
Escherichia coli (strain K12)
| 83,333 | 303 | 33,759 |
3D-structure;Cytolysis;Direct protein sequencing;Disulfide bond;Hemolysis;Host cell membrane;Host membrane;Membrane;Periplasm;Reference proteome;Secreted;Toxin;Transmembrane;Transmembrane helix;Virulence
|
GO:0005576; GO:0016020; GO:0020002; GO:0042597; GO:0042802; GO:0044179; GO:0090729
|
Evidence at protein level
| 5 |
SUBCELLULAR LOCATION: Secreted. Periplasm. Host cell membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. Note=Exported from the cell by outer membrane vesicles. Also found in the periplasmic space.
| null |
TRANSMEM 183..203; /note="Helical"; /evidence="ECO:0000255"
|
PF06109;
|
IPR027018;
|
1QOY;2WCD;4PHO;4PHQ;6MRT;6MRU;6MRW;
|
cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Gammaproteobacteria (class), Enterobacterales (order), Enterobacteriaceae (family), Escherichia (genus), Escherichia coli (species)
|
hlyE clyA hpr sheA ycgD b1182 JW5181
| true |
Escherichia coli
| 4 |
row_458
| false | null |
3,993 |
P43530
|
MKNITFIFFILLASPLYANGDKLYRADSRPPDEIKRSGGLMPRGHNEYFDRGTQMNINLYDHARGTQTGFVRYDDGYVSTSLSLRSAHLAGQSILSGYSTYYIYVIATAPNMFNVNDVLGVYSPHPYEQEVSALGGIPYSQIYGWYRVNFGVIDERLHRNREYRDRYYRNLNIAPAEDGYRLAGFPPDHQAWREEPWIHHAPQGCGNSSRTITGDTCNEETQNLSTIYLRKYQSKVKRQIFSDYQSEVDIYNRIRNEL
|
Heat-labile enterotoxin A chain (LT-A, human) (LTH-A)
|
Escherichia coli O78:H11 (strain H10407 / ETEC)
| 316,401 | 258 | 29,872 |
Disulfide bond;Enterotoxin;Plasmid;Signal;Toxin;Virulence
|
GO:0005615; GO:0090729
|
Inferred from homology
| 3 | null |
SIGNAL 1..18; /evidence="ECO:0000250"
| null |
PF01375;
|
IPR001144;
| null |
cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Gammaproteobacteria (class), Enterobacterales (order), Enterobacteriaceae (family), Escherichia (genus), Escherichia coli (species)
|
eltA ltpA toxA ETEC_p666_0660
| true |
Escherichia coli
| 5 |
row_3836
| false | null |
71 |
B7UI22
|
MINPVTNTQGVSPINTKYAEHVVKNIYPKIKHDYFNESPNIYDKKYISGITRGVAELKQEEFVNEKARRFSYMKTMYSVCPEAFEPISRNEASTPEGSWLTVISGKRPMGQFSVDSLYNPDLHALCELPDICCKIFPKENNDFLYIVVVYRNDSPLGEQRANRFIELYNIKRDIMQELNYELPELKAVKSEMIIAREMGEIFSYMPGEIDSYMKYINNKLSKIE
|
Cysteine S-methyltransferase NleE (EC 2.1.1.-) (Effector protein NleE) (Non-LEE-encoded type III effector E)
|
Escherichia coli O127:H6 (strain E2348/69 / EPEC)
| 574,521 | 224 | 26,057 |
Host nucleus;Methyltransferase;Reference proteome;S-adenosyl-L-methionine;Secreted;Toxin;Transferase;Virulence
|
GO:0005576; GO:0032259; GO:0042025; GO:0085034; GO:0090729; GO:0106363
|
Evidence at protein level
| 5 |
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:17984206}. Host nucleus {ECO:0000269|PubMed:17984206}. Note=Secreted via the type III secretion system (T3SS) (PubMed:17984206). Localizes in the nucleus of the infected cells (PubMed:17984206). {ECO:0000269|PubMed:17984206}.
| null | null |
PF20798;
|
IPR048901;
| null |
cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Gammaproteobacteria (class), Enterobacterales (order), Enterobacteriaceae (family), Escherichia (genus), Escherichia coli (species), Escherichia coli O127:H6 (serotype)
|
nleE E2348C_3232
| true |
Escherichia coli
| 6 |
row_65
| false | null |
5,661 |
D0Z6T1
|
MNKVKCYVLFTALLSSLCAYGAPQSITELCSEYRNTQIYTINDKILSYTESMAGKREMVIITFKSGATFQVEVPGSQHIDSQKKAIERMKDTLRITYLTETKIDKLCVWNNKTPNSIAAISMEN
|
Heat-labile enterotoxin B chain (LT-B, human) (LTH-B)
|
Escherichia coli O78:H11 (strain H10407 / ETEC)
| 316,401 | 124 | 14,028 |
Disulfide bond;Enterotoxin;Plasmid;Signal;Toxin;Virulence
|
GO:0005576; GO:0090729
|
Inferred from homology
| 2 | null |
SIGNAL 1..21; /evidence="ECO:0000250"
| null |
PF01376;
|
IPR008992;IPR001835;
| null |
cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Gammaproteobacteria (class), Enterobacterales (order), Enterobacteriaceae (family), Escherichia (genus), Escherichia coli (species)
|
eltB ltpB ETEC_p666_0650
| true |
Escherichia coli
| 7 |
row_5420
| false | null |
239 |
P0A968
|
MEKGTVKWFNNAKGFGFICPEGGGEDIFAHYSTIQMDGYRTLKAGQSVQFDVHQGPKGNHASVIVPVEVEAAVA
|
Cold shock-like protein CspD (CSP-D)
|
Escherichia coli (strain K12)
| 83,333 | 74 | 7,969 |
Cytoplasm;Direct protein sequencing;DNA replication inhibitor;DNA-binding;Reference proteome;RNA-binding;Toxin
|
GO:0003676; GO:0003697; GO:0003723; GO:0005829; GO:0006355; GO:0008156; GO:0010468; GO:0042594; GO:0042803; GO:0090729
|
Evidence at protein level
| 5 |
SUBCELLULAR LOCATION: Cytoplasm.
| null | null |
PF00313;
|
IPR012156;IPR050181;IPR011129;IPR019844;IPR002059;IPR012751;IPR012340;
| null |
cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Gammaproteobacteria (class), Enterobacterales (order), Enterobacteriaceae (family), Escherichia (genus), Escherichia coli (species)
|
cspD cspH ybjA b0880 JW0864
| true |
Escherichia coli
| 8 |
row_223
| false | null |
6,825 |
P64454
|
MSLYQHMLVFYAVMAAIAFLITWFLSHDKKRIRFLSAFLVGATWPMSFPVALLFSLF
|
Orphan toxin OrtT
|
Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)
| 199,310 | 57 | 6,646 |
Cell inner membrane;Cell membrane;Membrane;Reference proteome;Stress response;Toxin;Transmembrane;Transmembrane helix
|
GO:0005886; GO:0090729
|
Inferred from homology
| 2 |
SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250|UniProtKB:P64453}; Multi-pass membrane protein {ECO:0000305}.
| null |
TRANSMEM 6..26; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 34..54; /note="Helical"; /evidence="ECO:0000255"
|
PF10753;
|
IPR019689;
| null |
cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Gammaproteobacteria (class), Enterobacterales (order), Enterobacteriaceae (family), Escherichia (genus), Escherichia coli (species)
|
ortT c1870
| true |
Escherichia coli
| 9 |
row_6572
| false | null |
4,597 |
Q4JHE3
|
MNVFFMFSLLFLAALESCADVRRNPLEECFREADYEEFLEIARNGLKKTSNPKHVVVVGAGMAGLSAAYVLAGAGHKVTLLEASERVGGRVHTYRNEKEGWYVNLGPMRLPERHRIIREYIRKFGLKLNEFFQENENAWYFIRNIRKRVWEVKKDPGVFKYPVKPSEEGKSASQLYRESLKKVIEELKRTNCSYILNKYDTYSTKEYLIKEGNLSRGAVDMIGDLLNEDSSYYLSFIESLKSDDLFSYEKRFDEIVGGFDQLPISMYQAIAEMVHLNAQVIKIQHNAEKVRVAYQTPAKTLSYVTADYVIVCSSSRAARRIYFEPPLPPKKAHALRSIHYKSGTKIFLTCSKKFWEADGIHGGKSTTDLPSRFIYYPNHNFTSGVGVIVAYTISDDADFFQSLDIKTSADIVINDLSLIHQLPKKEIQALCYPSMIKKWSLDKYAMGSITSFAPYQFQDFIERVAAPVGRIYFAGEYTARVHGWLDSTIKSGLTAARDVNRASQKPSRRQLSNDNEL
|
L-amino-acid oxidase (LAAO) (LAO) (EC 1.4.3.2)
|
Oxyuranus scutellatus scutellatus (Australian taipan) (Coastal taipan)
| 8,667 | 517 | 59,070 |
Antibiotic;Antimicrobial;Apoptosis;Cytolysis;Disulfide bond;FAD;Flavoprotein;Glycoprotein;Hemolysis;Hemostasis impairing toxin;Oxidoreductase;Secreted;Signal;Toxin
|
GO:0001716; GO:0005576; GO:0006915; GO:0009063; GO:0031640; GO:0042742; GO:0090729
|
Evidence at transcript level
| 3 |
SUBCELLULAR LOCATION: Secreted {ECO:0000305|PubMed:16261251}.
|
SIGNAL 1..18; /evidence="ECO:0000255"
| null |
PF01593;
|
IPR002937;IPR036188;IPR001613;IPR050281;
| null |
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Elapidae (family), Hydrophiinae (subfamily), Oxyuranus (genus), Oxyuranus scutellatus (species)
| null | true |
Oxyuranus scutellatus
| 0 |
row_4375
| false | null |
2,031 |
Q3I5F4
|
MSMLCYTLIIVFLIGIWAAPKSEDNVPLGSPATSDLSDTSCAQTHEGLKTSRNTDQRHPAPKKAEDQELGSAANIIVDPKLFQKRRFQSPRVLFSTQPPPLSRDEQSVEFLDNEDTLNRNIRAKRETHPVHNLGEYSVCDSISVWVANKTEAMDIKGKPVTVMVDVNLNNHVFKQYFFETKCRNPNPVPSGCRGIDSGHWNSYCTTTQTFVRALTMEGNQASWRFIRIDTACVCVISRKTENF
|
Venom nerve growth factor (v-NGF) (vNGF)
|
Oxyuranus scutellatus scutellatus (Australian taipan) (Coastal taipan)
| 8,667 | 243 | 27,382 |
Cleavage on pair of basic residues;Disulfide bond;Glycoprotein;Growth factor;Lipid-binding;Metalloenzyme inhibitor;Metalloprotease inhibitor;Protease inhibitor;Secreted;Signal;Toxin
|
GO:0005163; GO:0005615; GO:0007169; GO:0008021; GO:0008083; GO:0008191; GO:0008289; GO:0021675; GO:0030424; GO:0030425; GO:0038180; GO:0043524; GO:0048812; GO:0050804; GO:0090729
|
Evidence at protein level
| 4 |
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:21801740}.
|
SIGNAL 1..18; /evidence="ECO:0000255"
| null |
PF00243;
|
IPR029034;IPR020408;IPR002072;IPR020425;IPR019846;IPR020433;
| null |
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Elapidae (family), Hydrophiinae (subfamily), Oxyuranus (genus), Oxyuranus scutellatus (species)
| null | true |
Oxyuranus scutellatus
| 1 |
row_1950
| false | null |
7,078 |
Q3SB07
|
MIAFTVLLSLAAVLQQSSGTVDFASESSNKKDYRKEIVDKHNDLRRSVKPTARNMLQMKWNSRAAQNAKRWANRCTFAHSPPYTRTVGKLRCGENIFMSSQPFAWSGVVQAWYDEVKKFVYGIGAKPPSSVIGHYTQVVWYKSHLLGCASAKCSSTKYLYVCQYCPAGNIIGSIATPYKSGPPCGDCPSACDNGLCTNPCKHNNDFSNCKALAKKSKCQTEWIKSKCPATCFCRTEII
|
Cysteine-rich venom protein pseudechetoxin-like (CRVP)
|
Oxyuranus scutellatus scutellatus (Australian taipan) (Coastal taipan)
| 8,667 | 238 | 26,410 |
Disulfide bond;Ion channel impairing toxin;Neurotoxin;Secreted;Signal;Toxin
|
GO:0005576; GO:0090729; GO:0099106
|
Evidence at transcript level
| 2 |
SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
|
SIGNAL 1..19; /evidence="ECO:0000250"
| null |
PF00188;PF08562;
|
IPR018244;IPR014044;IPR035940;IPR042076;IPR001283;IPR013871;IPR034117;IPR003582;
| null |
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Elapidae (family), Hydrophiinae (subfamily), Oxyuranus (genus), Oxyuranus scutellatus (species)
| null | true |
Oxyuranus scutellatus
| 2 |
row_6800
| false | null |
635 |
Q45Z47
|
MHPAHLLVLLAVCVSLLGASDIPPLPLNLAQFGFMIRCANGGSRSPLDYTDYGCYCGKGGRGTPVDDLDRCCQVHDECYGEAEKRLGCSPFVTLYSWKCYGKAPSCNTKTDCQRFVCNCDAKAAECFARSPYQKKNWNINTKARCK
|
Phospholipase A2 OS2 (PLA2) (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase)
|
Oxyuranus scutellatus scutellatus (Australian taipan) (Coastal taipan)
| 8,667 | 146 | 16,104 |
Calcium;Direct protein sequencing;Disulfide bond;Hydrolase;Lipid degradation;Lipid metabolism;Metal-binding;Myotoxin;Neurotoxin;Presynaptic neurotoxin;Secreted;Signal;Toxin
|
GO:0005509; GO:0005543; GO:0005576; GO:0006644; GO:0016042; GO:0047498; GO:0050482; GO:0090729
|
Evidence at protein level
| 5 |
SUBCELLULAR LOCATION: Secreted.
|
SIGNAL 1..27; /evidence="ECO:0000255"
| null |
PF00068;
|
IPR001211;IPR033112;IPR016090;IPR036444;IPR033113;
| null |
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Elapidae (family), Hydrophiinae (subfamily), Oxyuranus (genus), Oxyuranus scutellatus (species)
| null | true |
Oxyuranus scutellatus
| 3 |
row_594
| false | null |
174 |
P00614
|
NLLQFGFMIRCANRRSRPVWHYMDYGCYCGKGGSGTPVDDLDRCCQVHDECYGEAVRRFGCAPYWTLYSWKCYGKAPTCNTKTRCQRFVCRCDAKAAECFARSPYQNSNWNINTKARCR
|
Basic phospholipase A2 taipoxin alpha chain (svPLA2) (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase)
|
Oxyuranus scutellatus scutellatus (Australian taipan) (Coastal taipan)
| 8,667 | 119 | 13,829 |
Calcium;Direct protein sequencing;Disulfide bond;Hydrolase;Lipid degradation;Lipid metabolism;Metal-binding;Neurotoxin;Presynaptic neurotoxin;Secreted;Toxin
|
GO:0005509; GO:0005543; GO:0005576; GO:0006644; GO:0016042; GO:0047498; GO:0050482; GO:0090729
|
Evidence at protein level
| 5 |
SUBCELLULAR LOCATION: Secreted.
| null | null |
PF00068;
|
IPR001211;IPR033112;IPR016090;IPR036444;IPR033113;
| null |
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Elapidae (family), Hydrophiinae (subfamily), Oxyuranus (genus), Oxyuranus scutellatus (species)
| null | true |
Oxyuranus scutellatus
| 4 |
row_161
| false | null |
1,856 |
P83228
|
MVGLSRLAGGGLLLLLLLALLPLALDGKPAPLPQALPEALAGGTTALRRDVTEEQQQQLVAEESSGPAAGRSDPKIGDGCFGLPLDHIGSVSGLGCNRPVQNRPKQIPGGS
|
Natriuretic peptide TNP-b (Taipan natriuretic peptide) (Venom natriuretic peptide OxsSNPb)
|
Oxyuranus scutellatus scutellatus (Australian taipan) (Coastal taipan)
| 8,667 | 111 | 11,252 |
Direct protein sequencing;Disulfide bond;Hypotensive agent;Secreted;Signal;Toxin;Vasoactive;Vasodilator
|
GO:0005179; GO:0005576; GO:0008217; GO:0042311; GO:0090729
|
Evidence at protein level
| 4 |
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:15652496}.
|
SIGNAL 1..27; /evidence="ECO:0000255"
| null |
PF00212;
|
IPR000663;IPR030480;
| null |
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Elapidae (family), Hydrophiinae (subfamily), Oxyuranus (genus), Oxyuranus scutellatus (species)
| null | true |
Oxyuranus scutellatus
| 5 |
row_1781
| false | null |
5,208 |
A8HDK9
|
MKTLLLTLVVVTIVCLDLGYTRRCFTTPSVRSERCPPGQEVCYTKTWTDGHGGSRGKRVDLGCAATCPTPKKKDIKIICCSTDNCNTFPKWP
|
Long neurotoxin 1 (LNTX-1)
|
Oxyuranus scutellatus scutellatus (Australian taipan) (Coastal taipan)
| 8,667 | 92 | 10,183 |
3D-structure;Acetylcholine receptor inhibiting toxin;Disulfide bond;Ion channel impairing toxin;Neurotoxin;Postsynaptic neurotoxin;Secreted;Signal;Toxin
|
GO:0005576; GO:0030550; GO:0090729; GO:0099106
|
Evidence at protein level
| 2 |
SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
|
SIGNAL 1..21; /evidence="ECO:0000250"
| null |
PF21947;
|
IPR003571;IPR045860;IPR018354;IPR054131;
|
8D9Y;
|
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Elapidae (family), Hydrophiinae (subfamily), Oxyuranus (genus), Oxyuranus scutellatus (species)
| null | true |
Oxyuranus scutellatus
| 6 |
row_4975
| false | null |
69 |
B7S4N9
|
MSSGGLLLLLGLLTLWEVLTPVSSKDRPKFCHLPPKPGPCRAAIPRFYYNPHSKQCEKFIYGGCHGNANSFKTPDECNYTCLGVSLPK
|
Kunitz-type serine protease inhibitor taicotoxin (Taicatoxin, serine protease inhibitor component) (TCX) (TSPI) (Venom protease inhibitor 1) (Venom protease inhibitor 2)
|
Oxyuranus scutellatus scutellatus (Australian taipan) (Coastal taipan)
| 8,667 | 88 | 9,711 |
Blood coagulation cascade inhibiting toxin;Calcium channel impairing toxin;Calcium-activated potassium channel impairing toxin;Direct protein sequencing;Disulfide bond;Hemostasis impairing toxin;Ion channel impairing toxin;Neurotoxin;Potassium channel impairing toxin;Protease inhibitor;Secreted;Serine protease inhibitor;Signal;Toxin;Voltage-gated calcium channel impairing toxin
|
GO:0004867; GO:0005246; GO:0005615; GO:0015459; GO:0090729
|
Evidence at protein level
| 5 |
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:1485334}.
|
SIGNAL 1..24; /evidence="ECO:0000269|PubMed:1485334, ECO:0000269|PubMed:21843588"
| null |
PF00014;
|
IPR002223;IPR036880;IPR020901;IPR050098;
| null |
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Elapidae (family), Hydrophiinae (subfamily), Oxyuranus (genus), Oxyuranus scutellatus (species)
| null | true |
Oxyuranus scutellatus
| 7 |
row_63
| false | null |
2,036 |
Q45Z11
|
MKTLLLTLVVVTIVCLDLGYTMTCYNQQSSEAKTTTTCSGGVSSCYKKTWSDGRGTIIERGCGCPSVKKGIERICCRTDKCNN
|
Short neurotoxin 1 (SNTX-1) (Toxin 3)
|
Oxyuranus scutellatus scutellatus (Australian taipan) (Coastal taipan)
| 8,667 | 83 | 9,025 |
Acetylcholine receptor inhibiting toxin;Direct protein sequencing;Disulfide bond;Ion channel impairing toxin;Neurotoxin;Postsynaptic neurotoxin;Secreted;Signal;Toxin
|
GO:0005576; GO:0030550; GO:0090729; GO:0099106
|
Evidence at protein level
| 4 |
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:8672493}.
|
SIGNAL 1..21; /evidence="ECO:0000269|PubMed:8672493"
| null |
PF21947;
|
IPR003571;IPR045860;IPR018354;IPR054131;
| null |
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Elapidae (family), Hydrophiinae (subfamily), Oxyuranus (genus), Oxyuranus scutellatus (species)
| null | true |
Oxyuranus scutellatus
| 8 |
row_1954
| false | null |
5,203 |
A8HDK2
|
MKTLLLTLVVMTIVCLDLGYTLTCYMNPSGTMVCKEHETMCYQLIVWTFQYRVLYLKGCTSSCPGGNNRACCSTDLCNN
|
Short neurotoxin 3 (SNTX-3) (Three-finger toxin) (3FTx)
|
Oxyuranus scutellatus scutellatus (Australian taipan) (Coastal taipan)
| 8,667 | 79 | 8,877 |
Disulfide bond;Secreted;Signal;Toxin
|
GO:0005576; GO:0090729
|
Inferred from homology
| 2 |
SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
|
SIGNAL 1..23; /evidence="ECO:0000250"
| null |
PF21947;
|
IPR003571;IPR045860;IPR054131;
| null |
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Elapidae (family), Hydrophiinae (subfamily), Oxyuranus (genus), Oxyuranus scutellatus (species)
| null | true |
Oxyuranus scutellatus
| 9 |
row_4970
| false | null |
3,333 |
P0CB06
|
MTCYNQQSSEAKTTTTCSGGVSSCYKKTWSDIRGTIIERGCGCPSVKKGIERICCRTDKCNN
|
Short neurotoxin 2 (SNTX-2)
|
Oxyuranus scutellatus scutellatus (Australian taipan) (Coastal taipan)
| 8,667 | 62 | 6,790 |
Acetylcholine receptor inhibiting toxin;Direct protein sequencing;Disulfide bond;Ion channel impairing toxin;Neurotoxin;Postsynaptic neurotoxin;Secreted;Toxin
|
GO:0005576; GO:0030550; GO:0090729; GO:0099106
|
Evidence at protein level
| 3 |
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:8672493}.
| null | null |
PF21947;
|
IPR003571;IPR045860;IPR018354;IPR054131;
| null |
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Elapidae (family), Hydrophiinae (subfamily), Oxyuranus (genus), Oxyuranus scutellatus (species)
| null | true |
Oxyuranus scutellatus
| 10 |
row_3215
| false | null |
7,073 |
Q3SAX8
|
PAAGLSDPKIGNGCFGFPIDRIGSVSGLGCNRLVQNPPKPISGES
|
Natriuretic peptide OsNP-d
|
Oxyuranus scutellatus scutellatus (Australian taipan) (Coastal taipan)
| 8,667 | 45 | 4,524 |
Disulfide bond;Hypotensive agent;Secreted;Toxin;Vasoactive;Vasodilator
|
GO:0005179; GO:0005576; GO:0008217; GO:0042311; GO:0090729
|
Evidence at transcript level
| 2 |
SUBCELLULAR LOCATION: Secreted {ECO:0000305|PubMed:16261251}.
| null | null |
PF00212;
|
IPR000663;IPR030480;IPR002408;
| null |
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Elapidae (family), Hydrophiinae (subfamily), Oxyuranus (genus), Oxyuranus scutellatus (species)
| null | true |
Oxyuranus scutellatus
| 11 |
row_6795
| false | null |
4,266 |
P83231
|
SDSKIGNGCFGFPLDRIGSVSGLGCNRIMQNPPKKFSGE
|
Natriuretic peptide TNP-c (Taipan natriuretic peptide) (Venom natriuretic peptide OxsSNPc)
|
Oxyuranus scutellatus canni (Papuan taipan)
| 183,720 | 39 | 4,115 |
Direct protein sequencing;Disulfide bond;Hypotensive agent;Secreted;Toxin;Vasoactive;Vasodilator
|
GO:0005179; GO:0005576; GO:0008217; GO:0042311; GO:0090729
|
Evidence at protein level
| 3 |
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:15652496}.
| null | null |
PF00212;
|
IPR000663;IPR030480;IPR002408;
| null |
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Elapidae (family), Hydrophiinae (subfamily), Oxyuranus (genus), Oxyuranus scutellatus (species)
| null | true |
Oxyuranus scutellatus
| 12 |
row_4099
| false | null |
4,262 |
P83225
|
SDSKIGDGCFGLPLDHIGSVSGLGCNRPVQNRPKK
|
Natriuretic peptide TNP-a (Taipan natriuretic peptide) (Venom natriuretic peptide OxsSNPa)
|
Oxyuranus scutellatus scutellatus (Australian taipan) (Coastal taipan)
| 8,667 | 35 | 3,653 |
Direct protein sequencing;Disulfide bond;Hypotensive agent;Secreted;Toxin;Vasoactive;Vasodilator
|
GO:0005179; GO:0005576; GO:0008217; GO:0042311; GO:0090729
|
Evidence at protein level
| 3 |
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:15652496}.
| null | null |
PF00212;
|
IPR000663;IPR030480;
| null |
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Elapidae (family), Hydrophiinae (subfamily), Oxyuranus (genus), Oxyuranus scutellatus (species)
| null | true |
Oxyuranus scutellatus
| 13 |
row_4095
| false | null |
2,116 |
Q7LZG2
|
NLAQFGFMIRCANGGSRSALDYADYGC
|
Phospholipase A2 taicatoxin (TCX) (svPLA2) (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase)
|
Oxyuranus scutellatus scutellatus (Australian taipan) (Coastal taipan)
| 8,667 | 27 | 2,901 |
Calcium;Calcium-activated potassium channel impairing toxin;Direct protein sequencing;Disulfide bond;Hydrolase;Ion channel impairing toxin;Lipid degradation;Lipid metabolism;Metal-binding;Neurotoxin;Potassium channel impairing toxin;Secreted;Toxin
|
GO:0004623; GO:0005576; GO:0006644; GO:0015459; GO:0016042; GO:0046872; GO:0050482; GO:0090729
|
Evidence at protein level
| 4 |
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:1373076, ECO:0000269|PubMed:1485334}.
| null | null | null |
IPR036444;
| null |
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Elapidae (family), Hydrophiinae (subfamily), Oxyuranus (genus), Oxyuranus scutellatus (species)
| null | true |
Oxyuranus scutellatus
| 14 |
row_2032
| false | null |
1,506 |
P0DKT7
|
NLLQFGYMIRCANGRSRPVW
|
Basic phospholipase A2 cannitoxin alpha chain (svPLA2) (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase)
|
Oxyuranus scutellatus canni (Papuan taipan)
| 183,720 | 20 | 2,382 |
Calcium;Direct protein sequencing;Disulfide bond;Hydrolase;Lipid degradation;Lipid metabolism;Metal-binding;Neurotoxin;Presynaptic neurotoxin;Secreted;Toxin
|
GO:0004623; GO:0005576; GO:0016042; GO:0046872; GO:0090729
|
Evidence at protein level
| 4 |
SUBCELLULAR LOCATION: Secreted.
| null | null | null | null | null |
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Elapidae (family), Hydrophiinae (subfamily), Oxyuranus (genus), Oxyuranus scutellatus (species)
| null | true |
Oxyuranus scutellatus
| 15 |
row_1443
| false | null |
547 |
P84809
|
MISVQVIFIAFISIIAFSMVCGGNVFPNRELGILYGCKGYGNAFCDKVCKMHLARGGGRCGEPNPVMWACECIDIDEDNGYFLNALEKQCPLLKG
|
Lipolysis-activating peptide 1-beta chain (BotLVP1-beta) (LVP1-beta)
|
Buthus occitanus tunetanus (Common European scorpion) (Buthus tunetanus)
| 6,871 | 95 | 10,386 |
Direct protein sequencing;Disulfide bond;G-protein coupled receptor impairing toxin;Ion channel impairing toxin;Neurotoxin;Potassium channel impairing toxin;RNA editing;Secreted;Signal;Toxin;Voltage-gated potassium channel impairing toxin;Voltage-gated sodium channel impairing toxin
|
GO:0005576; GO:0006952; GO:0008200; GO:0015459; GO:0017080; GO:0050996; GO:0090729
|
Evidence at protein level
| 5 |
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:15680238}.
|
SIGNAL 1..22; /evidence="ECO:0000269|PubMed:15680238"
| null | null |
IPR044062;IPR036574;
| null |
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Protostomia (clade), Ecdysozoa (clade), Panarthropoda (clade), Arthropoda (phylum), Chelicerata (subphylum), Arachnida (class), Scorpiones (order), Buthida (parvorder), Buthoidea (superfamily), Buthidae (family), Buthus (genus), Buthus occitanus (species)
| null | true |
Buthus occitanus
| 0 |
row_511
| false | null |
548 |
P84810
|
MMKLVLFGIIVILFSLIGSIHGISGNYPLNPYGGYYYCTILGENEYCKKICRIHGVRYGYCYDSACWCETLKDEDVSVWNAVKKHCKNPYL
|
Lipolysis-activating peptide 1-alpha chain (BotLVP1-alpha) (LVP1-alpha) [Cleaved into: Neurotoxin BmKBTx-like]
|
Buthus occitanus tunetanus (Common European scorpion) (Buthus tunetanus)
| 6,871 | 91 | 10,457 |
Direct protein sequencing;Disulfide bond;G-protein coupled receptor impairing toxin;Ion channel impairing toxin;Neurotoxin;Potassium channel impairing toxin;RNA editing;Secreted;Signal;Toxin;Voltage-gated potassium channel impairing toxin;Voltage-gated sodium channel impairing toxin
|
GO:0005576; GO:0006952; GO:0015459; GO:0019871; GO:0050996; GO:0090729
|
Evidence at protein level
| 5 |
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:15680238}.
|
SIGNAL 1..22; /evidence="ECO:0000269|PubMed:15680238"
| null |
PF00537;
|
IPR044062;IPR036574;IPR002061;
| null |
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Protostomia (clade), Ecdysozoa (clade), Panarthropoda (clade), Arthropoda (phylum), Chelicerata (subphylum), Arachnida (class), Scorpiones (order), Buthida (parvorder), Buthoidea (superfamily), Buthidae (family), Buthus (genus), Buthus occitanus (species)
| null | true |
Buthus occitanus
| 1 |
row_512
| false | null |
4,512 |
Q17254
|
MSSLMISTAMKGKAPYRQVRDGYIAQPHNCAYHCLKISSGCDTLCKENGATSGHCGHKSGHGSACWCKDLPDKVGIIVHGEKCHR
|
Alpha-insect toxin Bot14 (BotXIV) (Neurotoxin XIV)
|
Buthus occitanus tunetanus (Common European scorpion) (Buthus tunetanus)
| 6,871 | 85 | 9,174 |
Disulfide bond;Ion channel impairing toxin;Neurotoxin;Secreted;Signal;Toxin;Voltage-gated sodium channel impairing toxin
|
GO:0005576; GO:0006952; GO:0019871; GO:0090729
|
Evidence at transcript level
| 3 |
SUBCELLULAR LOCATION: Secreted.
|
SIGNAL 1..18; /evidence="ECO:0000255"
| null |
PF00537;
|
IPR044062;IPR003614;IPR036574;IPR018218;IPR002061;
| null |
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Protostomia (clade), Ecdysozoa (clade), Panarthropoda (clade), Arthropoda (phylum), Chelicerata (subphylum), Arachnida (class), Scorpiones (order), Buthida (parvorder), Buthoidea (superfamily), Buthidae (family), Buthus (genus), Buthus occitanus (species)
| null | true |
Buthus occitanus
| 2 |
row_4313
| false | null |
195 |
P01485
|
LVMAGVESVKDGYIVDDRNCTYFCGRNAYCNEECTKLKGESGYCQWASPYGNACYCYKVPDHVRTKGPGRCN
|
Alpha-mammal toxin Bot3 (Bot III) (BotIII) (Neurotoxin III)
|
Buthus occitanus tunetanus (Common European scorpion) (Buthus tunetanus)
| 6,871 | 72 | 8,059 |
Amidation;Direct protein sequencing;Disulfide bond;Ion channel impairing toxin;Neurotoxin;Secreted;Signal;Toxin;Voltage-gated sodium channel impairing toxin
|
GO:0005576; GO:0006952; GO:0019871; GO:0090729
|
Evidence at protein level
| 5 |
SUBCELLULAR LOCATION: Secreted {ECO:0000269|Ref.2}.
|
SIGNAL <1..8; /evidence="ECO:0000269|Ref.2"
| null |
PF00537;
|
IPR044062;IPR003614;IPR036574;IPR018218;IPR002061;
| null |
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Protostomia (clade), Ecdysozoa (clade), Panarthropoda (clade), Arthropoda (phylum), Chelicerata (subphylum), Arachnida (class), Scorpiones (order), Buthida (parvorder), Buthoidea (superfamily), Buthidae (family), Buthus (genus), Buthus occitanus (species)
| null | true |
Buthus occitanus
| 3 |
row_182
| false | null |
1,351 |
P04099
|
AEIKVRDGYIVYPNNCVYHCGLNPYCNDLCTKNGAKSGYCQWLTKWGNACYCYALPEKVPIKDPSYKCYS
|
Alpha-toxin Bot9 (BotIX) (Neurotoxin 9) (Neurotoxin IX)
|
Buthus occitanus tunetanus (Common European scorpion) (Buthus tunetanus)
| 6,871 | 70 | 7,998 |
Direct protein sequencing;Disulfide bond;Ion channel impairing toxin;Neurotoxin;Secreted;Toxin;Voltage-gated sodium channel impairing toxin
|
GO:0005576; GO:0006952; GO:0019871; GO:0090729
|
Evidence at protein level
| 4 |
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:27528512, ECO:0000269|PubMed:6729843}.
| null | null |
PF00537;
|
IPR044062;IPR003614;IPR036574;IPR018218;IPR002061;
| null |
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Protostomia (clade), Ecdysozoa (clade), Panarthropoda (clade), Arthropoda (phylum), Chelicerata (subphylum), Arachnida (class), Scorpiones (order), Buthida (parvorder), Buthoidea (superfamily), Buthidae (family), Buthus (genus), Buthus occitanus (species)
| null | true |
Buthus occitanus
| 4 |
row_1292
| false | null |
6,791 |
P60258
|
VRDAYIAQNYNCVYHCGRDAYCNELCSKNGAKSRTRGGYCHWFGPHGDACWCIDLPNNVPIKVEGKCHRK
|
Toxin Boma6d (Alpha-neurotoxin Bom alpha-6d)
|
Buthus occitanus mardochei (Moroccan scorpion) (Buthus mardochei)
| 6,869 | 70 | 7,964 |
Disulfide bond;Ion channel impairing toxin;Neurotoxin;Secreted;Toxin;Voltage-gated sodium channel impairing toxin
|
GO:0005576; GO:0006952; GO:0019871; GO:0090729
|
Inferred from homology
| 2 |
SUBCELLULAR LOCATION: Secreted.
| null | null |
PF00537;
|
IPR044062;IPR003614;IPR036574;IPR018218;IPR002061;
| null |
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Protostomia (clade), Ecdysozoa (clade), Panarthropoda (clade), Arthropoda (phylum), Chelicerata (subphylum), Arachnida (class), Scorpiones (order), Buthida (parvorder), Buthoidea (superfamily), Buthidae (family), Buthus (genus), Buthus occitanus (species)
| null | true |
Buthus occitanus
| 5 |
row_6538
| false | null |
3,844 |
P13488
|
GRDGYIAQPENCVYHCFPGSSGCDTLCKEKGATSGHCGFLPGSGVACWCDNLPNKVPIVVGGEKCH
|
Alpha-like toxin Bom3 (Bom III) (BomIII)
|
Buthus occitanus mardochei (Moroccan scorpion) (Buthus mardochei)
| 6,869 | 66 | 6,872 |
Direct protein sequencing;Disulfide bond;Ion channel impairing toxin;Neurotoxin;Secreted;Toxin;Voltage-gated sodium channel impairing toxin
|
GO:0005576; GO:0006952; GO:0019871; GO:0090729
|
Evidence at protein level
| 3 |
SUBCELLULAR LOCATION: Secreted.
| null | null |
PF00537;
|
IPR044062;IPR003614;IPR036574;IPR018218;IPR002061;
| null |
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Protostomia (clade), Ecdysozoa (clade), Panarthropoda (clade), Arthropoda (phylum), Chelicerata (subphylum), Arachnida (class), Scorpiones (order), Buthida (parvorder), Buthoidea (superfamily), Buthidae (family), Buthus (genus), Buthus occitanus (species)
| null | true |
Buthus occitanus
| 6 |
row_3693
| false | null |
6,785 |
P59896
|
GRDAYIAQPENCVYECAKSSYCNDLCTKNGAKSGYCQWLGRWGNACYCIDLPDKVPIRIEGKCHFA
|
Toxin BomPI (Neurotoxin PI)
|
Buthus occitanus mardochei (Moroccan scorpion) (Buthus mardochei)
| 6,869 | 66 | 7,398 |
Direct protein sequencing;Disulfide bond;Ion channel impairing toxin;Neurotoxin;Secreted;Toxin;Voltage-gated sodium channel impairing toxin
|
GO:0005576; GO:0006952; GO:0019871; GO:0090729
|
Evidence at protein level
| 2 |
SUBCELLULAR LOCATION: Secreted.
| null | null |
PF00537;
|
IPR044062;IPR003614;IPR036574;IPR018218;IPR002061;
| null |
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Protostomia (clade), Ecdysozoa (clade), Panarthropoda (clade), Arthropoda (phylum), Chelicerata (subphylum), Arachnida (class), Scorpiones (order), Buthida (parvorder), Buthoidea (superfamily), Buthidae (family), Buthus (genus), Buthus occitanus (species)
| null | true |
Buthus occitanus
| 7 |
row_6532
| false | null |
6,790 |
P60257
|
VRDAYIAQNYNCVYTCFKDAHCNDLCTKNGASSGYCQWAGKYGNACWCYALPDNVPIRIPGKCHRK
|
Toxin Boma6c (Alpha-neurotoxin Bom alpha-6c)
|
Buthus occitanus mardochei (Moroccan scorpion) (Buthus mardochei)
| 6,869 | 66 | 7,440 |
Disulfide bond;Ion channel impairing toxin;Neurotoxin;Secreted;Toxin;Voltage-gated sodium channel impairing toxin
|
GO:0005576; GO:0006952; GO:0019871; GO:0090729
|
Inferred from homology
| 2 |
SUBCELLULAR LOCATION: Secreted.
| null | null |
PF00537;
|
IPR044062;IPR003614;IPR036574;IPR018218;IPR002061;
| null |
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Protostomia (clade), Ecdysozoa (clade), Panarthropoda (clade), Arthropoda (phylum), Chelicerata (subphylum), Arachnida (class), Scorpiones (order), Buthida (parvorder), Buthoidea (superfamily), Buthidae (family), Buthus (genus), Buthus occitanus (species)
| null | true |
Buthus occitanus
| 8 |
row_6537
| false | null |
6,792 |
P60259
|
VRDAYIAQNYNCVYACARDAYCNDLCTKNGARSGLFATFGPHGDACWCIALPNNVPLKVQGKCHRK
|
Toxin Boma6e (Alpha-neurotoxin Bom alpha-6e)
|
Buthus occitanus mardochei (Moroccan scorpion) (Buthus mardochei)
| 6,869 | 66 | 7,267 |
Disulfide bond;Ion channel impairing toxin;Neurotoxin;Secreted;Toxin;Voltage-gated sodium channel impairing toxin
|
GO:0005576; GO:0006952; GO:0019871; GO:0090729
|
Inferred from homology
| 2 |
SUBCELLULAR LOCATION: Secreted.
| null | null |
PF00537;
|
IPR044062;IPR003614;IPR036574;IPR018218;IPR002061;
| null |
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Protostomia (clade), Ecdysozoa (clade), Panarthropoda (clade), Arthropoda (phylum), Chelicerata (subphylum), Arachnida (class), Scorpiones (order), Buthida (parvorder), Buthoidea (superfamily), Buthidae (family), Buthus (genus), Buthus occitanus (species)
| null | true |
Buthus occitanus
| 9 |
row_6539
| false | null |
1,776 |
P59354
|
GRDAYIAQPENCVYECAKNSYCNDLCTKNGAKSGYCQWLGKYGNACWCEDLPDNVPIRIPGKCHF
|
Alpha-like toxin Bom4 (Bom IV) (BomIV)
|
Buthus occitanus mardochei (Moroccan scorpion) (Buthus mardochei)
| 6,869 | 65 | 7,296 |
Direct protein sequencing;Disulfide bond;Ion channel impairing toxin;Neurotoxin;Secreted;Toxin;Voltage-gated sodium channel impairing toxin
|
GO:0005576; GO:0006952; GO:0019871; GO:0090729
|
Evidence at protein level
| 4 |
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:10103091}.
| null | null |
PF00537;
|
IPR044062;IPR003614;IPR036574;IPR018218;IPR002061;
| null |
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Protostomia (clade), Ecdysozoa (clade), Panarthropoda (clade), Arthropoda (phylum), Chelicerata (subphylum), Arachnida (class), Scorpiones (order), Buthida (parvorder), Buthoidea (superfamily), Buthidae (family), Buthus (genus), Buthus occitanus (species)
| null | true |
Buthus occitanus
| 10 |
row_1702
| false | null |
3,093 |
P01486
|
LKDGYIVDDRNCTYFCGTNAYCNEECVKLKGESGYCQWVGRYGNACWCYKLPDHVRTVQAGRCRS
|
Alpha-toxin Bot11 (BotXI) (Neurotoxin 11) (Toxin XI)
|
Buthus occitanus tunetanus (Common European scorpion) (Buthus tunetanus)
| 6,871 | 65 | 7,468 |
Direct protein sequencing;Disulfide bond;Ion channel impairing toxin;Neurotoxin;Secreted;Toxin;Voltage-gated sodium channel impairing toxin
|
GO:0005576; GO:0006952; GO:0019871; GO:0090729
|
Evidence at protein level
| 3 |
SUBCELLULAR LOCATION: Secreted.
| null | null |
PF00537;
|
IPR044062;IPR003614;IPR036574;IPR018218;IPR002061;
| null |
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Protostomia (clade), Ecdysozoa (clade), Panarthropoda (clade), Arthropoda (phylum), Chelicerata (subphylum), Arachnida (class), Scorpiones (order), Buthida (parvorder), Buthoidea (superfamily), Buthidae (family), Buthus (genus), Buthus occitanus (species)
| null | true |
Buthus occitanus
| 11 |
row_2991
| false | null |
4,092 |
P59864
|
DGYPKQKNGCKYDCIINNKWCNGICKMHGGYYGYCWGWGLACWCEGLPEDKKWWYETNKCGR
|
Beta-insect depressant toxin BotIT6 (Insect toxin 6)
|
Buthus occitanus tunetanus (Common European scorpion) (Buthus tunetanus)
| 6,871 | 62 | 7,323 |
Direct protein sequencing;Disulfide bond;Ion channel impairing toxin;Neurotoxin;Secreted;Toxin;Voltage-gated sodium channel impairing toxin
|
GO:0005576; GO:0006952; GO:0019871; GO:0090729
|
Evidence at protein level
| 3 |
SUBCELLULAR LOCATION: Secreted.
| null | null |
PF00537;
|
IPR044062;IPR003614;IPR036574;IPR018218;IPR002061;
| null |
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Protostomia (clade), Ecdysozoa (clade), Panarthropoda (clade), Arthropoda (phylum), Chelicerata (subphylum), Arachnida (class), Scorpiones (order), Buthida (parvorder), Buthoidea (superfamily), Buthidae (family), Buthus (genus), Buthus occitanus (species)
| null | true |
Buthus occitanus
| 12 |
row_3927
| false | null |
1,726 |
P55903
|
DGYIRRRDGCKVSCLFGNEGCDKECKAYGGSYGYCWTWGLACWCEGLPDDKTWKSETNTCG
|
Beta-insect depressant toxin BotIT4 (Insect toxin 4)
|
Buthus occitanus tunetanus (Common European scorpion) (Buthus tunetanus)
| 6,871 | 61 | 6,845 |
Amidation;Direct protein sequencing;Disulfide bond;Ion channel impairing toxin;Neurotoxin;Secreted;Toxin;Voltage-gated sodium channel impairing toxin
|
GO:0005576; GO:0006952; GO:0019871; GO:0090729
|
Evidence at protein level
| 4 |
SUBCELLULAR LOCATION: Secreted.
| null | null |
PF00537;
|
IPR044062;IPR003614;IPR036574;IPR018218;IPR002061;
| null |
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Protostomia (clade), Ecdysozoa (clade), Panarthropoda (clade), Arthropoda (phylum), Chelicerata (subphylum), Arachnida (class), Scorpiones (order), Buthida (parvorder), Buthoidea (superfamily), Buthidae (family), Buthus (genus), Buthus occitanus (species)
| null | true |
Buthus occitanus
| 13 |
row_1652
| false | null |
4,091 |
P59863
|
DGYIKGYKGCKITCVINDDYCDTECKAEGGTYGYCWKWGLACWCEDLPDEKRWKSETNTC
|
Beta-toxin BotIT2 (Bot IT2) (Insect toxin 2)
|
Buthus occitanus tunetanus (Common European scorpion) (Buthus tunetanus)
| 6,871 | 60 | 6,918 |
Direct protein sequencing;Disulfide bond;Ion channel impairing toxin;Neurotoxin;Secreted;Toxin;Voltage-gated sodium channel impairing toxin
|
GO:0005576; GO:0006952; GO:0019871; GO:0090729
|
Evidence at protein level
| 3 |
SUBCELLULAR LOCATION: Secreted.
| null | null |
PF00537;
|
IPR044062;IPR003614;IPR036574;IPR018218;IPR002061;
| null |
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Protostomia (clade), Ecdysozoa (clade), Panarthropoda (clade), Arthropoda (phylum), Chelicerata (subphylum), Arachnida (class), Scorpiones (order), Buthida (parvorder), Buthoidea (superfamily), Buthidae (family), Buthus (genus), Buthus occitanus (species)
| null | true |
Buthus occitanus
| 14 |
row_3926
| false | null |
1,520 |
P0DL62
|
AGSMDSCSETGVCMKACSERIRQVENDNKCPAGECICTT
|
Potassium channel toxin alpha-KTx 31.1 (Kbot55)
|
Buthus occitanus tunetanus (Common European scorpion) (Buthus tunetanus)
| 6,871 | 39 | 4,129 |
Direct protein sequencing;Disulfide bond;Ion channel impairing toxin;Potassium channel impairing toxin;Secreted;Toxin;Voltage-gated potassium channel impairing toxin
|
GO:0005576; GO:0015459; GO:0090729
|
Evidence at protein level
| 4 |
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:26079392}.
| null | null | null | null | null |
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Protostomia (clade), Ecdysozoa (clade), Panarthropoda (clade), Arthropoda (phylum), Chelicerata (subphylum), Arachnida (class), Scorpiones (order), Buthida (parvorder), Buthoidea (superfamily), Buthidae (family), Buthus (genus), Buthus occitanus (species)
| null | true |
Buthus occitanus
| 15 |
row_1456
| false | null |
2,689 |
C0HM60
|
TNGVPGKCTKPGGCSTYCRDTTGTMGLCKNSKCYCNKY
|
Toxin Bot33 (Potassium channel toxin alpha-KTx)
|
Buthus occitanus tunetanus (Common European scorpion) (Buthus tunetanus)
| 6,871 | 38 | 4,042 |
Direct protein sequencing;Disulfide bond;Ion channel impairing toxin;Neurotoxin;Potassium channel impairing toxin;Secreted;Toxin
|
GO:0005576; GO:0015459; GO:0090729
|
Evidence at protein level
| 3 |
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:36364113}.
| null | null | null |
IPR036574;
| null |
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Protostomia (clade), Ecdysozoa (clade), Panarthropoda (clade), Arthropoda (phylum), Chelicerata (subphylum), Arachnida (class), Scorpiones (order), Buthida (parvorder), Buthoidea (superfamily), Buthidae (family), Buthus (genus), Buthus occitanus (species)
| null | true |
Buthus occitanus
| 16 |
row_2598
| false | null |
1,775 |
P59290
|
VGIPVSCKHSGQCIKPCKDAGMRFGKCMNRKCDCTPK
|
Potassium channel toxin alpha-KTx 3.9 (Kaliotoxin-3) (KTX-3)
|
Buthus occitanus tunetanus (Common European scorpion) (Buthus tunetanus)
| 6,871 | 37 | 4,028 |
Direct protein sequencing;Disulfide bond;Ion channel impairing toxin;Neurotoxin;Potassium channel impairing toxin;Secreted;Toxin
|
GO:0005576; GO:0008200; GO:0015459; GO:0090729
|
Evidence at protein level
| 4 |
SUBCELLULAR LOCATION: Secreted.
| null | null |
PF00451;
|
IPR036574;IPR001947;
| null |
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Protostomia (clade), Ecdysozoa (clade), Panarthropoda (clade), Arthropoda (phylum), Chelicerata (subphylum), Arachnida (class), Scorpiones (order), Buthida (parvorder), Buthoidea (superfamily), Buthidae (family), Buthus (genus), Buthus occitanus (species)
|
KTX3
| true |
Buthus occitanus
| 17 |
row_1701
| false | null |
79 |
C0HJQ2
|
AACYSSDCRVKCRAMGFSSGKCIDSKCKCYK
|
Potassium channel toxin alpha-KTx 19.2 (Toxin Kbot21)
|
Buthus occitanus tunetanus (Common European scorpion) (Buthus tunetanus)
| 6,871 | 31 | 3,400 |
Direct protein sequencing;Disulfide bond;Ion channel impairing toxin;Neurotoxin;Potassium channel impairing toxin;Secreted;Toxin;Voltage-gated potassium channel impairing toxin
|
GO:0005576; GO:0019870; GO:0044562; GO:0090729
|
Evidence at protein level
| 5 |
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:26398235}.
| null | null |
PF00451;
|
IPR036574;IPR001947;
| null |
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Protostomia (clade), Ecdysozoa (clade), Panarthropoda (clade), Arthropoda (phylum), Chelicerata (subphylum), Arachnida (class), Scorpiones (order), Buthida (parvorder), Buthoidea (superfamily), Buthidae (family), Buthus (genus), Buthus occitanus (species)
| null | true |
Buthus occitanus
| 18 |
row_73
| false | null |
1,894 |
P84744
|
VGCEECPMHCKGKHAVPTCDDGVCNCNV
|
Potassium channel toxin alpha-KTx 9.5 (Kbot1)
|
Buthus occitanus tunetanus (Common European scorpion) (Buthus tunetanus)
| 6,871 | 28 | 2,949 |
Amidation;Calcium-activated potassium channel impairing toxin;Direct protein sequencing;Disulfide bond;Ion channel impairing toxin;Neurotoxin;Potassium channel impairing toxin;Secreted;Toxin;Voltage-gated potassium channel impairing toxin
|
GO:0005576; GO:0019870; GO:0043267; GO:0090729
|
Evidence at protein level
| 4 |
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:15165720}.
| null | null |
PF05453;
|
IPR036574;IPR008911;
| null |
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Protostomia (clade), Ecdysozoa (clade), Panarthropoda (clade), Arthropoda (phylum), Chelicerata (subphylum), Arachnida (class), Scorpiones (order), Buthida (parvorder), Buthoidea (superfamily), Buthidae (family), Buthus (genus), Buthus occitanus (species)
| null | true |
Buthus occitanus
| 19 |
row_1817
| false | null |
6,055 |
P04097
|
VRDAYIAQNYNCVYTCFKNDYCND
|
Neurotoxin 5 (Neurotoxin V)
|
Buthus occitanus tunetanus (Common European scorpion) (Buthus tunetanus)
| 6,871 | 24 | 2,896 |
Direct protein sequencing;Ion channel impairing toxin;Neurotoxin;Secreted;Toxin;Voltage-gated sodium channel impairing toxin
|
GO:0005576; GO:0019871; GO:0090729
|
Evidence at protein level
| 2 |
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:6729843}.
| null | null |
PF00537;
|
IPR044062;IPR036574;IPR002061;
| null |
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Protostomia (clade), Ecdysozoa (clade), Panarthropoda (clade), Arthropoda (phylum), Chelicerata (subphylum), Arachnida (class), Scorpiones (order), Buthida (parvorder), Buthoidea (superfamily), Buthidae (family), Buthus (genus), Buthus occitanus (species)
| null | true |
Buthus occitanus
| 20 |
row_5814
| false | null |
2,684 |
C0HLZ7
|
IDCGTVMIPSECDPKSS
|
RK peptide (Disintegrin-like peptide)
|
Buthus occitanus tunetanus (Common European scorpion) (Buthus tunetanus)
| 6,871 | 17 | 1,782 |
Cell adhesion impairing toxin;Direct protein sequencing;Disulfide bond;Secreted;Toxin
|
GO:0005576; GO:0090729
|
Evidence at protein level
| 3 |
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:30287364}.
| null | null | null | null | null |
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Protostomia (clade), Ecdysozoa (clade), Panarthropoda (clade), Arthropoda (phylum), Chelicerata (subphylum), Arachnida (class), Scorpiones (order), Buthida (parvorder), Buthoidea (superfamily), Buthidae (family), Buthus (genus), Buthus occitanus (species)
| null | true |
Buthus occitanus
| 21 |
row_2593
| false | null |
3,699 |
P0DQU9
|
IDCSKVNLTAECSS
|
RK1 peptide (Disintegrin-like peptide)
|
Buthus occitanus tunetanus (Common European scorpion) (Buthus tunetanus)
| 6,871 | 14 | 1,470 |
Cell adhesion impairing toxin;Direct protein sequencing;Disulfide bond;Secreted;Toxin
|
GO:0005576; GO:0090729
|
Evidence at protein level
| 3 |
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:29366787}.
| null | null | null | null | null |
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Protostomia (clade), Ecdysozoa (clade), Panarthropoda (clade), Arthropoda (phylum), Chelicerata (subphylum), Arachnida (class), Scorpiones (order), Buthida (parvorder), Buthoidea (superfamily), Buthidae (family), Buthus (genus), Buthus occitanus (species)
| null | true |
Buthus occitanus
| 22 |
row_3558
| false | null |
5,618 |
C6EVG6
|
MQMDWLFIAVVSAIGLLSSGVPGTQGAYTTEQCRALNGTCRFYACFPKNVVIGKCDWLGWGCCARTPLERCTAKKGTCTASGCTETDTDHGPCDGGAQCCQRDPVKYCKFHGNVCGRGKCPMDHIPIGEQCMPGYPCCKRDGPAYCKSKGGKCLRRCSQIVPTDIIGVCADGVPCCKSRQSTG
|
Helofensin-1 (Lethal toxin 1)
|
Heloderma suspectum cinctum (Banded Gila monster)
| 537,493 | 183 | 19,544 |
Repeat;Secreted;Signal;Toxin
|
GO:0005576; GO:0006952; GO:0090729
|
Evidence at transcript level
| 2 |
SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
|
SIGNAL 1..26; /evidence="ECO:0000250"
| null |
PF00711;
|
IPR001855;
| null |
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Anguimorpha (infraorder), Neoanguimorpha (clade), Helodermatidae (family), Heloderma (genus), Heloderma suspectum (species)
| null | true |
Heloderma suspectum
| 0 |
row_5377
| false | null |
97 |
C6EVG7
|
MNPRLACSTWLPLLLVLFTLDQGRANPVERGQEYRSLSKRFDDDSTELILEPRASEENGPPYQPLVPRASDENVPPAYVPLVPRASDENVPPPPLQMPLIPRASEQKGPPFNPPPFVDYEPRAANENALRKLIKRSFERSPGRNKRLSPGDGCFGQKIDRIGAVSGMGCNSVSSQGKK
|
Natriuretic and helokinestatin peptides [Cleaved into: Helokinestatin-1 (HKS-1); Helokinestatin-2 (HKS-2); Helokinestatin-3 (HKS-3); Helokinestatin-4 (HKS-4); Natriuretic peptide]
|
Heloderma suspectum cinctum (Banded Gila monster)
| 537,493 | 178 | 19,672 |
Bradykinin receptor impairing toxin;Cleavage on pair of basic residues;Direct protein sequencing;Disulfide bond;G-protein coupled receptor impairing toxin;Hypotensive agent;Secreted;Signal;Toxin;Vasoactive
|
GO:0003085; GO:0005179; GO:0005615; GO:0005737; GO:0006182; GO:0007168; GO:0007218; GO:0019934; GO:0051427; GO:0090729; GO:0097746
|
Evidence at protein level
| 5 |
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:19837656}.
|
SIGNAL 1..25; /evidence="ECO:0000255"
| null |
PF00212;
|
IPR000663;IPR030480;IPR050787;IPR002408;
| null |
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Anguimorpha (infraorder), Neoanguimorpha (clade), Helodermatidae (family), Heloderma (genus), Heloderma suspectum (species)
| null | true |
Heloderma suspectum
| 1 |
row_91
| false | null |
2,734 |
C6EVG1
|
MKIILWLCVFGLFLATLFPISWQMPVESGLSSEDSASSESFASKIKRHGEGTFTSDLSKQMEEEAVRLFIEWLKNGGPSSGAPPPSG
|
Exendin-4
|
Heloderma suspectum cinctum (Banded Gila monster)
| 537,493 | 87 | 9,479 |
Amidation;Cleavage on pair of basic residues;G-protein coupled receptor impairing toxin;Hypotensive agent;Secreted;Signal;Toxin
|
GO:0005179; GO:0005576; GO:0008217; GO:0090729
|
Evidence at transcript level
| 3 |
SUBCELLULAR LOCATION: Secreted.
|
SIGNAL 1..23; /evidence="ECO:0000255"
| null |
PF00123;
|
IPR000532;
| null |
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Anguimorpha (infraorder), Neoanguimorpha (clade), Helodermatidae (family), Heloderma (genus), Heloderma suspectum (species)
| null | true |
Heloderma suspectum
| 2 |
row_2642
| false | null |
5,617 |
C6EVG2
|
MKSILWLCVFGLLIATLFPVSWQMAIKSRLSSEDSETDQRLFESKRHSDAIFTEEYSKLLAKLALQKYLASILGSRTSPPPPSR
|
Exendin-2-long [Cleaved into: Exendin-2 (Helodermin) (VIP-like 2)]
|
Heloderma suspectum cinctum (Banded Gila monster)
| 537,493 | 84 | 9,531 |
Cleavage on pair of basic residues;G-protein coupled receptor impairing toxin;Hypotensive agent;Secreted;Signal;Toxin
|
GO:0005179; GO:0005576; GO:0008217; GO:0090729
|
Evidence at transcript level
| 2 |
SUBCELLULAR LOCATION: Secreted.
|
SIGNAL 1..23; /evidence="ECO:0000255"
| null |
PF00123;
|
IPR000532;
| null |
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Anguimorpha (infraorder), Neoanguimorpha (clade), Helodermatidae (family), Heloderma (genus), Heloderma suspectum (species)
| null | true |
Heloderma suspectum
| 3 |
row_5376
| false | null |
138 |
G9I930
|
MDKMNPAHLLVLAAVCVSLLGASSIPPQALNLNQFRLMIKCTNDRVWADFVDYGCYCVARDSNTPVDDLDRCCQAQKQCYDEAVKVHGCKPLVMFYSFECRYLASDLDCSGNNTKCRNFVCNCDRTATLCILTATYNRNNHKIDPSRCQ
|
Basic phospholipase A2 homolog MitTx-beta (svPLA2 homolog)
|
Micrurus tener tener (Texas coral snake)
| 1,114,302 | 149 | 16,793 |
3D-structure;Direct protein sequencing;Disulfide bond;Ion channel impairing toxin;Proton-gated sodium channel impairing toxin;Secreted;Signal;Toxin
|
GO:0005509; GO:0005543; GO:0005576; GO:0006644; GO:0016042; GO:0047498; GO:0050482; GO:0090729; GO:0099106
|
Evidence at protein level
| 5 |
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:22094702}.
|
SIGNAL 1..30; /evidence="ECO:0000269|PubMed:22094702"
| null |
PF00068;
|
IPR001211;IPR033112;IPR016090;IPR036444;
|
4NTW;4NTX;4NTY;
|
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Elapidae (family), Elapinae (subfamily), Micrurus (genus), Micrurus tener (species)
| null | true |
Micrurus tener
| 0 |
row_129
| false | null |
1,268 |
G9I929
|
MSSGGLLLLLGLLTLCAELTPVSSQIRPAFCYEDPPFFQKCGAFVDSYYFNRSRITCVHFFYGQCDVNQNHFTTMSECNRVCHG
|
Kunitz-type neurotoxin MitTx-alpha
|
Micrurus tener tener (Texas coral snake)
| 1,114,302 | 84 | 9,498 |
3D-structure;Direct protein sequencing;Disulfide bond;Ion channel impairing toxin;Protease inhibitor;Proton-gated sodium channel impairing toxin;Pyrrolidone carboxylic acid;Secreted;Serine protease inhibitor;Signal;Toxin
|
GO:0004867; GO:0005576; GO:0090729; GO:0099106
|
Evidence at protein level
| 4 |
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:22094702}.
|
SIGNAL 1..24; /evidence="ECO:0000269|PubMed:22094702"
| null |
PF00014;
|
IPR002223;IPR036880;
|
4NTW;4NTX;4NTY;
|
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Metazoa (kingdom), Eumetazoa (clade), Bilateria (clade), Deuterostomia (clade), Chordata (phylum), Craniata (subphylum), Vertebrata (clade), Gnathostomata (clade), Teleostomi (clade), Euteleostomi (clade), Sarcopterygii (superclass), Dipnotetrapodomorpha (clade), Tetrapoda (clade), Amniota (clade), Sauropsida (clade), Sauria (clade), Lepidosauria (class), Squamata (order), Bifurcata (clade), Unidentata (clade), Episquamata (clade), Toxicofera (clade), Serpentes (infraorder), Colubroidea (superfamily), Elapidae (family), Elapinae (subfamily), Micrurus (genus), Micrurus tener (species)
| null | true |
Micrurus tener
| 1 |
row_1211
| false | null |
140 |
I1C083
|
MYFEEGRLFFIKSQFNGRVLDVEDGSTEDDANIIVYTQKYEDCLNQLWRYENGYFINAKSAKVLDIRGGEMQPESQIIQYAQKMVEEAANQRWAIDEDGYIFCEARPDLVLDIQGAEDEDCVPVILYERREGEVSANQRWELVPFEG
|
Mucoricin (EC 3.2.2.22) (Ricin-like toxin) (rRNA N-glycosidase)
|
Rhizopus delemar (strain RA 99-880 / ATCC MYA-4621 / FGSC 9543 / NRRL 43880) (Mucormycosis agent) (Rhizopus arrhizus var. delemar)
| 246,409 | 147 | 17,138 |
Hydrolase;Protein synthesis inhibitor;Reference proteome;Secreted;Toxin;Virulence
|
GO:0005576; GO:0017148; GO:0019057; GO:0030598; GO:0045007; GO:0090729
|
Evidence at protein level
| 5 |
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:33462434}.
| null | null |
PF00652;
|
IPR035992;IPR000772;
| null |
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Fungi (kingdom), Fungi incertae sedis (no rank), Mucoromycota (phylum), Mucoromycotina (subphylum), Mucoromycetes (class), Mucorales (order), Mucorineae (suborder), Rhizopodaceae (family), Rhizopus (genus), Rhizopus delemar (species)
|
RLT1 RO3G_06568
| true |
Rhizopus delemar
| 0 |
row_130
| false | null |
155 |
O05442
|
MAPLAVDPAALDSAGGAVVAAGAGLGAVISSLTAALAGCAGMAGDDPAGAVFGRSYDGSAAALVQAMSVARNGLCNLGDGVRMSAHNYSLAEAMSDVAGRAAPLPAPPPSGCVGVGAPPSAVGGGGGAPKGWGWVAPYIGMIWPNGDSTKLRAAAVAWRSAGTQFALTEIQSTAGPMGVIRAQQLPEAGLIESAFADAYASTTAVVGQCHQLAAQLDAYAARIDAVHAAVLDLLARICDPLTGIKEVWEFLTDQDEDEIQRIAHDIAVVVDQFSGEVDALAAEITAVVSHAEAVITAMADHAGKQWDRFLHSNPVGVVIDGTGQQLKGFGEEAFGMAKDSWDLGPLRASIDPFGWYRSWEEMLTGMAPLAGLGGENAPGVVESWKQFGKSLIHWDEWTTNPNEALGKTVFDAATLALPGGPLSKLGSKGRDILAGVRGLKERLEPTTPHLEPPATPPRPGPQPPRIEPPESGHPAPAPAAKPAPVPANGPLPHSPTESKPPPVDRPAEPVAPSSASAGQPRVSAATTPGTHVPHGLPQPGEHVPAQAPPATTLLGGPPVESAPATAHQPQWATTPAAPAAAPHSTPGGVHSTESGPHGRSLSAHGSEPTHDGASHGSGHGSGSEPPGLHAPHREQQLAMHSNEPAGEGWHRLSDEAVDPQYGEPLSRHWDFTDNPADRSRINPVVAQLMEDPNAPFGRDPQGQPYTQERYQERFNSVGPWGQQYSNFPPNNGAVPGTRIAYTNLEKFLSDYGPQLDRIGGDQGKYLAIMEHGRPASWEQRALHVTSLRDPYHAYTIDWLPEGWFIEVSEVAPGCGQPGGSIQVRIFDHQNEMRKVEELIRRGVLRQ
|
Outer membrane channel protein CpnT (Channel protein with necrosis-inducing toxin) [Cleaved into: N-terminal channel domain; Tuberculosis necrotizing toxin (TNT) (NAD(+) glycohydrolase) (EC 3.2.2.5)]
|
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
| 83,332 | 846 | 88,335 |
3D-structure;Cell outer membrane;Host cytoplasm;Hydrolase;Ion transport;Membrane;NAD;Porin;Reference proteome;Secreted;Toxin;Transmembrane;Transmembrane beta strand;Transport;Virulence
|
GO:0001907; GO:0003953; GO:0005576; GO:0005829; GO:0006811; GO:0009274; GO:0009279; GO:0009986; GO:0015288; GO:0044164; GO:0046930; GO:0050135; GO:0061809; GO:0090729
|
Evidence at protein level
| 5 |
SUBCELLULAR LOCATION: [N-terminal channel domain]: Cell outer membrane {ECO:0000269|PubMed:24753609}.; SUBCELLULAR LOCATION: [Tuberculosis necrotizing toxin]: Secreted {ECO:0000269|PubMed:24753609}. Cell surface {ECO:0000269|PubMed:24753609}. Host cytoplasm, host cytosol {ECO:0000269|PubMed:26237511}. Note=Secreted into the cytosol of infected macrophages while the bacteria are still confined to the phagosome. Access to the macrophage cytosol depends on the ESX-1 / type VII secretion system (T7SS). {ECO:0000269|PubMed:26237511}.
| null | null |
PF14021;
|
IPR025331;
|
4QLP;
|
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
|
cpnT Rv3903c
| true |
Mycobacterium tuberculosis
| 0 |
row_142
| false | null |
577 |
P9WJ63
|
MARRARVDAELVRRGLARSRQQAAELIGAGKVRIDGLPAVKPATAVSDTTALTVVTDSERAWVSRGAHKLVGALEAFAIAVAGRRCLDAGASTGGFTEVLLDRGAAHVVAADVGYGQLAWSLRNDPRVVVLERTNARGLTPEAIGGRVDLVVADLSFISLATVLPALVGCASRDADIVPLVKPQFEVGKGQVGPGGVVHDPQLRARSVLAVARRAQELGWHSVGVKASPLPGPSGNVEYFLWLRTQTDRALSAKGLEDAVHRAISEGP
|
16S/23S rRNA (cytidine-2'-O)-methyltransferase TlyA (EC 2.1.1.226) (EC 2.1.1.227) (16S rRNA (cytidine1409-2'-O)-methyltransferase) (23S rRNA (cytidine1920-2'-O)-methyltransferase) (Hemolysin TlyA)
|
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
| 83,332 | 268 | 28,074 |
3D-structure;Cell wall;Cytolysis;Cytoplasm;Hemolysis;Host cell membrane;Host membrane;Membrane;Methyltransferase;Reference proteome;Ribosome biogenesis;RNA-binding;rRNA processing;S-adenosyl-L-methionine;Secreted;Toxin;Transferase;Virulence
|
GO:0001897; GO:0003723; GO:0005576; GO:0005737; GO:0008649; GO:0016020; GO:0020002; GO:0031167; GO:0090729
|
Evidence at protein level
| 5 |
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:20854656}. Secreted, cell wall {ECO:0000269|PubMed:26347855}. Host cell membrane {ECO:0000269|PubMed:20854656}. Note=Can bind to target membranes such as macrophage phagosomal membranes (PubMed:20854656). In native and recombinant hosts (M.smegmatis and E.coli), M.tuberculosis TlyA can reach the bacterial surface in functional form and colocalizes with the HBHA protein which is known to be part of cell-wall (PubMed:26347855). TlyA does not seem to depend on either Tat or Sec pathways for translocation to cell-wall (PubMed:26347855). Appears to be capable of reaching the extra-cellular milieu using a vesicle mediated transport (PubMed:26347855). {ECO:0000269|PubMed:20854656, ECO:0000269|PubMed:26347855}.
| null | null |
PF01728;PF01479;
|
IPR004538;IPR002877;IPR002942;IPR036986;IPR029063;IPR047048;
|
5KS2;5KYG;7S0S;
|
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
|
tlyA Rv1694
| true |
Mycobacterium tuberculosis
| 1 |
row_541
| false | null |
1,953 |
P9WJ62
|
MARRARVDAELVRRGLARSRQQAAELIGAGKVRIDGLPAVKPATAVSDTTALTVVTDSERAWVSRGAHKLVGALEAFAIAVAGRRCLDAGASTGGFTEVLLDRGAAHVVAADVGYGQLAWSLRNDPRVVVLERTNARGLTPEAIGGRVDLVVADLSFISLATVLPALVGCASRDADIVPLVKPQFEVGKGQVGPGGVVHDPQLRARSVLAVARRAQELGWHSVGVKASPLPGPSGNVEYFLWLRTQTDRALSAKGLEDAVHRAISEGP
|
16S/23S rRNA (cytidine-2'-O)-methyltransferase TlyA (EC 2.1.1.226) (EC 2.1.1.227) (16S rRNA (cytidine1409-2'-O)-methyltransferase) (23S rRNA (cytidine1920-2'-O)-methyltransferase) (Hemolysin TlyA)
|
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
| 83,331 | 268 | 28,074 |
3D-structure;Cell wall;Cytolysis;Cytoplasm;Hemolysis;Host cell membrane;Host membrane;Membrane;Methyltransferase;Reference proteome;Ribosome biogenesis;RNA-binding;rRNA processing;S-adenosyl-L-methionine;Secreted;Toxin;Transferase;Virulence
|
GO:0003723; GO:0005576; GO:0005737; GO:0006364; GO:0008168; GO:0016020; GO:0020002; GO:0031640; GO:0032259; GO:0090729
|
Evidence at protein level
| 4 |
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:P9WJ63}. Secreted, cell wall {ECO:0000250|UniProtKB:P9WJ63}. Host cell membrane {ECO:0000250|UniProtKB:P9WJ63}. Note=Can bind to target membranes such as macrophage phagosomal membranes. In native and recombinant hosts (M.smegmatis and E.coli), M.tuberculosis TlyA can reach the bacterial surface in functional form and colocalizes with the HBHA protein which is known to be part of cell-wall. TlyA does not seem to depend on either Tat or Sec pathways for translocation to cell-wall. Appears to be capable of reaching the extra-cellular milieu using a vesicle mediated transport. {ECO:0000250|UniProtKB:P9WJ63}.
| null | null |
PF01728;PF01479;
|
IPR004538;IPR002877;IPR002942;IPR036986;IPR029063;IPR047048;
|
5EOV;
|
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Actinomycetota (phylum), Actinomycetes (class), Mycobacteriales (order), Mycobacteriaceae (family), Mycobacterium (genus), Mycobacterium tuberculosis complex (no rank), Mycobacterium tuberculosis (species)
|
tlyA MT1733
| true |
Mycobacterium tuberculosis
| 2 |
row_1874
| false | null |
1,296 |
O31506
|
MKVFEAKTLLSEATDRAKEYKELRTQMVNLRKALKGVADLSDSEFSGKGASNIKAFYHDHVGVADQWIDYIDMKIAFFNSIAGAAEDKGLSDAYIEESFLEHELANANKKSKSIMSEQKKAMKDILNDIDDILPLDLFSTETFKDELADANDKRKKTLEKLDALDEDLKTEYALSEPNEQFIKSDFQKLQEATGKGKNATPIHYNAKAYRESDIHKKKGDIEKRTEAYLKIKKEEAKEREIEKLKERLKNYDYADADEFYEMAKTIGYENLTAEQQRYFTQIENTRELEAGFKGVAVGLYDSGKDAVVGLWDMVTDPGGTVEAITGAMAHPIKTYEAISAAIEESYQKDMVNGDTYSRARWVSYAVGTVVTSIVGTKGVGAVSKTGTAAKVTTKVKTAASKSATAQKAITVSKQTVDHIKQKVNTGIEVSKKHVKTKLNQIGDLTLADILPYHPRHDLVPAGVPYNAVNGVTLKEGLQKFAKVILPKPYGTSSSGRRTPAPHVPPVTVKYGEHFARWSRKKVLKPNIIYKTKEGYTYTTDNYGRITSVKADLQLGEAKRNQYAQTNAGKPQDRKPDDDGGHLIATQFKGSGQFDNIVPMNSQINRSGGKWYEMEQEWAKALSKKPPKKVAVQIEPVYSGDSLRPSYFDVTYKIGSRKEISVSIKNQPGG
|
Toxin YeeF (DNase YeeF)
|
Bacillus subtilis (strain 168)
| 224,308 | 669 | 74,488 |
Cell membrane;Coiled coil;DNA-binding;Hydrolase;Membrane;Nuclease;Reference proteome;Toxin
|
GO:0003677; GO:0004518; GO:0005886; GO:0045121; GO:0090729
|
Evidence at protein level
| 4 |
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:22882210}. Membrane raft {ECO:0000269|PubMed:22882210}. Note=Present in detergent-resistant membrane (DRM) fractions that may be equivalent to eukaryotic membrane rafts; these rafts include proteins involved in signaling, molecule trafficking and protein secretion (PubMed:22882210). Delivery to target cells requires the type VII secretion system (T7SS) and YukE (PubMed:34280190). {ECO:0000269|PubMed:22882210, ECO:0000269|PubMed:34280190}.
| null | null |
PF13930;PF04740;
|
IPR051768;IPR044929;IPR044927;IPR006829;
| null |
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Bacillota (phylum), Bacilli (class), Bacillales (order), Bacillaceae (family), Bacillus (genus), Bacillus subtilis group (no rank), Bacillus subtilis (species), Bacillus subtilis subsp. subtilis (subspecies)
|
yeeF BSU06810
| true |
Bacillus subtilis
| 0 |
row_1237
| false | null |
1,297 |
O34330
|
MKVFEADSLLFEADKRTKEYKELRSQMVKLKKAFKEVANLDDSEFSGKGADNIKAFYHGHVGVTDQWIDLIDMKIAFLSSMSATLEDAKMSDAYIEESFLEHELANAYAKSKSIMSEQKKAMKDILNNINDILPLEIFSTEDFKDKLSSADDKREKTIDKLNKLDEDLKTEYAETEPNEQFIQQDFKKLQESTGKGKNATPIHYNAKAYRESDIHKKKGDIEKHSEAYLSVKKEEAKEREIKELKKKLNDGVSDPDEYLEIAKKVGYENLEPTQVQLAVQIEQAKQLEGAGEITWDIVKGVGVGLYDVGKDTVTGIWDFITDPGETLSALGNAAMHPVKTYDAISAAIEESYQKDMVNGDAYSRSRWVTYAIGSVAVAVVGTKGAGAINKADAAGKVINKASQAGKKIKDVKIPDLLPYNPKYKLALADNVPYNVVDSQNLKNELLTNAKKIPDGTRKPFTGQKKSPPWLNKEKYDAYEIEGKVKAKGKVKDVSRRVYTMKDIDINQKTEFGVTNLQLMKNGNAPYAKDGTQINLHHLIQEEPGPMLEIPNSLHTKYSDVIHQLKSDGESFRNDKVLKAQYESFRKRYWKWRAKQFENEN
|
Toxin YobL (DNase YobL)
|
Bacillus subtilis (strain 168)
| 224,308 | 600 | 67,770 |
Coiled coil;Hydrolase;Nuclease;Reference proteome;Secreted;Toxin
|
GO:0004518; GO:0005576; GO:0090729
|
Evidence at protein level
| 4 |
SUBCELLULAR LOCATION: Secreted {ECO:0000305|PubMed:34280190}. Note=Delivery to target cells requires the type VII secretion system (T7SS) and YukE. {ECO:0000269|PubMed:34280190}.
| null | null |
PF14411;PF04740;
|
IPR051768;IPR026834;IPR006829;
| null |
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Bacillota (phylum), Bacilli (class), Bacillales (order), Bacillaceae (family), Bacillus (genus), Bacillus subtilis group (no rank), Bacillus subtilis (species), Bacillus subtilis subsp. subtilis (subspecies)
|
yobL BSU19000
| true |
Bacillus subtilis
| 1 |
row_1238
| false | null |
3,001 |
O31998
|
MKVFEADSLLSEADKRTKEYKELRSQMVKLKKAFKAVADLDDSKFSGKGADNIKAFYHDHVGVTDQWIDLIDMKIVFLSSISAKLEDAKMSDAYIEESFLEHELVNAYTKSKSIMSEQKKAMKDILNDINDILPLEIFSTEDFKDKLSSADDKREKTIDKINKLDEDLKTEYAETEQNEQFIQQDFKKLQESTGKGKNATPIHYSAKAYRESDIHKKKGDIEQHSEAYLTVKKEEAKEREIKELKKKLNDGVSDPDEYLEIAKKVGYENLEPAQVQLAVQIEQAKQLEGAGEITWDIVKGVGVGLYDVGKDTVTGLWDFITDPGETLSALGNAVIHPVKTYDAISAAIEESYQKDMVNGDAYSRSRWVTYAIGSVAAAVIGTKGAGAINKADAAGKVINKASQAGKKIKDVKIPDLLPYNPKYDLAMAGDVPYNVVDGENLKNQLMSFAKGSDKEVKPFDVVDYRPSNSPLENHHGVMDVWAKHNVPNYVSRGSNTPTVALTKEQHNATKKVYREWLFEKTGKKVGGKVNWKEVSPREIQELTEKMFDAANVPKEARQQYYNAFNQYNFRK
|
Toxin YokI (DNase YokL) (SPbeta prophage-derived protein YokI)
|
Bacillus subtilis (strain 168)
| 224,308 | 571 | 64,261 |
Coiled coil;Hydrolase;Nuclease;Reference proteome;Secreted;Toxin
|
GO:0004518; GO:0005576; GO:0090729
|
Evidence at protein level
| 3 |
SUBCELLULAR LOCATION: Secreted {ECO:0000305|PubMed:34280190}. Note=Delivery to target cells requires the type VII secretion system (T7SS) and YukE. {ECO:0000269|PubMed:34280190}.
| null | null |
PF04740;PF15652;
|
IPR051768;IPR006829;IPR028900;
| null |
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Bacillota (phylum), Bacilli (class), Bacillales (order), Bacillaceae (family), Bacillus (genus), Bacillus subtilis group (no rank), Bacillus subtilis (species), Bacillus subtilis subsp. subtilis (subspecies)
|
yokI BSU21580
| true |
Bacillus subtilis
| 2 |
row_2902
| false | null |
3,989 |
P42296
|
MKTLDVHALHEGIQHTIEKLDKQKQQLEKLEKSVEHLAGMKDALKGKGGDAIRTFYEECHKPFLLFFGIFIDEYKKVLKQTQHAISSVESNSHGMIAEAFLSHDARHGVKHAREVTEQLTDAVNRQTSAIDHIVSLPTVNDSFFRMETEQAERLISDTLNKLFQFDGQQTQALEAAKSDFQTMKKYIDQLETMYTGPKIEITGYKSGSILKSQEEENINQIFGAINPQMKQADDSPMEMMLKKLAENEKSKVDSVVKTGDSKKVSKNIIVINGKVYNTSEHREHIKTDFSNAEVKQVVYNDTLYNVYISGNDMKLEPVVSLSDIKVDENGYVKILETAVELTGVYDLFKAATGRDPVSGEKVTGKDRVVASINSVPFAKIAKLEKLIDINKLINNGKKAKKASEVKNVAKDKGKIANDVSGSANKINSDLIKKYARDIEQRTGRELPKNQIDKLKEALRNKEYKKMSPIETAKHRTKFDKVKNKVIKEWEENTGQKWPVYKENVVSEKTGKIIRKKGDKYDAHHIIENTFGGEHEWWNMHPAKFPNEHQAGIHGTGSPANELFKGGKKK
|
Toxin YxiD (DNase YxiD)
|
Bacillus subtilis (strain 168)
| 224,308 | 569 | 64,326 |
Coiled coil;Hydrolase;Nuclease;Reference proteome;Secreted;Toxin
|
GO:0004518; GO:0005576; GO:0090729
|
Evidence at protein level
| 3 |
SUBCELLULAR LOCATION: Secreted {ECO:0000305|PubMed:34280190}. Note=Delivery to target cells requires the type VII secretion system (T7SS) and YukE. {ECO:0000269|PubMed:34280190}.
| null | null |
PF04740;PF14449;
|
IPR003615;IPR006829;IPR027797;
| null |
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Bacillota (phylum), Bacilli (class), Bacillales (order), Bacillaceae (family), Bacillus (genus), Bacillus subtilis group (no rank), Bacillus subtilis (species), Bacillus subtilis subsp. subtilis (subspecies)
|
yxiD J3D BSU39300
| true |
Bacillus subtilis
| 3 |
row_3832
| false | null |
1,716 |
P45942
|
MKVFEAKTLLTEAEKRAQEYKDLKSKMVKLKKAFKAVADLDDSEFSGKGANNIKSFYEDQAGIADQWIDLIEMKISFLTSIPGFLEDANLSDAYIEETFLAHELANAYTKSKSIMSEQKKAMKDILNDINDILPLDLFSTETFKNELSSAEKKRKEAIEKMDEVDQNLTSEYGLSEANEQMIQADYQALMNATAKGKSASPIHYNAKAYRDSEIHKMTEDVKKQSTDYISFKDQQAEQRRIAKEQEELANRPWYEKSWDAVCNFTGEVSGYYDYKRAADGVDPVTGEKLTAGQRVAAGAMAAAGYIPIVGWAGKLAKGGKAVYSTSKALYRADKALDVYKTPKTFHALQNSSKGLYGLASANGFSEAITGRDMFGNKVSKERQEQSLSGAMAMLVPFGARGINKKLNAKSSSRVSEASTNTSKKPKVPKTYKRPTYFRKGVRDKVWENAKDSTGSVKDPLTKQVMKKDEPWDMGHKPGYEFRKHQQSAMERNISRKQFLDEHNNPDHYQPELPSSNRSHKGEDMTDDYFGD
|
Toxin YqcG (DNase YqcG)
|
Bacillus subtilis (strain 168)
| 224,308 | 531 | 59,669 |
Coiled coil;Hydrolase;Nuclease;Reference proteome;Secreted;Toxin
|
GO:0004518; GO:0005576; GO:0090729
|
Evidence at protein level
| 4 |
SUBCELLULAR LOCATION: Secreted {ECO:0000305|PubMed:34280190}. Note=Delivery to target cells requires the type VII secretion system (T7SS) and YukE. {ECO:0000269|PubMed:34280190}.
| null | null |
PF14410;PF04740;PF14449;
|
IPR051768;IPR006829;IPR027797;IPR026835;
| null |
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Bacillota (phylum), Bacilli (class), Bacillales (order), Bacillaceae (family), Bacillus (genus), Bacillus subtilis group (no rank), Bacillus subtilis (species), Bacillus subtilis subsp. subtilis (subspecies)
|
yqcG BSU25860
| true |
Bacillus subtilis
| 4 |
row_1645
| false | null |
159 |
O34344
|
MKSKLLRLLIVSMVTILVFSLVGLSKESSTSAKENHTFSGEDYFRGLLFGQGEVGKLISNDLDPKLVKEANSTEGKKLVNDVVKFIKKDQPQYMDELKQSIDSKDPKKLIENMTKADQLIQKYAKKNENVKYSSNKVTPSCGLYAVCVAAGYLYVVGVNAVALQTAAAVTTAVWKYVAKYSSSASNNSDLEAAAAKTLKLIHQ
|
Sporulation delaying protein C (SdpC) (Cannibalism toxin SDP) (Killing factor SdpC) (Toxic peptide SdpC) [Cleaved into: Sporulation delaying protein (SDP)]
|
Bacillus subtilis (strain 168)
| 224,308 | 203 | 22,221 |
Antibiotic;Antimicrobial;Bacteriocin;Direct protein sequencing;Disulfide bond;Reference proteome;Secreted;Signal;Toxin;Virulence
|
GO:0001906; GO:0005576; GO:0031640; GO:0042742; GO:0090729
|
Evidence at protein level
| 5 |
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:12817086, ECO:0000269|PubMed:14568161, ECO:0000269|PubMed:23687264}. Note=Produces a secreted protein originating from this gene (PubMed:12817086), secreted by the general secretory pathway (PubMed:14568161).
|
SIGNAL 1..32; /evidence="ECO:0000269|PubMed:10816431"
| null | null |
IPR023888;
| null |
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Bacillota (phylum), Bacilli (class), Bacillales (order), Bacillaceae (family), Bacillus (genus), Bacillus subtilis group (no rank), Bacillus subtilis (species), Bacillus subtilis subsp. subtilis (subspecies)
|
sdpC yvaY BSU33770
| true |
Bacillus subtilis
| 5 |
row_146
| false | null |
6,965 |
P96723
|
MENEYDMKSIKEKGVDFEDLWFSSVSDEILDNPEDENGQPFTGLAYELYPNGQIIYFTKYKNGLAHGLTCEFYENGNKKSEKEYRYGQLHGISIIWFENGRKKSEQQYEHSILISEKNWDEEGNLLNKYEIDTDSPHFEILESRRETHINLGRE
|
Immunity protein YwqK
|
Bacillus subtilis (strain 168)
| 224,308 | 154 | 18,217 |
Cytoplasm;Reference proteome;Toxin
|
GO:0005737; GO:0090729
|
Evidence at protein level
| 2 |
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
| null | null |
PF07661;
|
IPR011652;
| null |
cellular organisms (no rank), Bacteria (domain), Bacillati (kingdom), Bacillota (phylum), Bacilli (class), Bacillales (order), Bacillaceae (family), Bacillus (genus), Bacillus subtilis group (no rank), Bacillus subtilis (species), Bacillus subtilis subsp. subtilis (subspecies)
|
ywqK BSU36180
| true |
Bacillus subtilis
| 6 |
row_6687
| false | null |
1,305 |
O74486
|
MKNKYYPLRSSMDELSAKNDNEIDLEKGPLPEYNSEDGSTLPPYSENINLKDPKQMGANNPNLFNTDESTTPPDYGEDSLSITHRENHSSGTADNSSTSPLKKAFLSFISIFVLNVPAVCYLTYKDALFKDYGKDEWVYFAVWCASCLMIFISLWYFYETWIKAVKVTVIFLAQCIKVTVVFLAQCVKVTSISLAKCVKLTAVFLAQCVKVTAVFLAQCVKVISIGLFNIRREMMIIIWLLWLIICCILFGCVKSGDLNLNKALIYSTCTISAVLLLIVSSVCIPFWTFERTLAKLAKVFLLQSGIVLVLNGTMFLRGKHFEWTGCEIEASVLFIMGNVLFLCEMECPGALIRTRNSIRNGIAFILEGAGRAIRGANDNNDIPLGEMEVESEV
|
Meiotic driver wtf19
|
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
| 284,812 | 393 | 43,945 |
Alternative initiation;Cytoplasm;Endoplasmic reticulum;Membrane;Reference proteome;Toxin;Transmembrane;Transmembrane helix;Vacuole
|
GO:0005737; GO:0005774; GO:0005789; GO:0005794; GO:0072324; GO:0110134
|
Evidence at transcript level
| 4 |
SUBCELLULAR LOCATION: [Isoform 1]: Spore membrane {ECO:0000250|UniProtKB:A0A218N034, ECO:0000255}; Multi-pass membrane protein {ECO:0000255}. Vacuole membrane {ECO:0000250|UniProtKB:A0A218N034, ECO:0000255}; Multi-pass membrane protein {ECO:0000255}. Note=Contained within spores expressing the isoform and localizes isoform 2 to the vacuole. {ECO:0000250|UniProtKB:A0A218N034}.; SUBCELLULAR LOCATION: [Isoform 2]: Ascus epiplasm {ECO:0000250|UniProtKB:A0A218N034}. Cytoplasm {ECO:0000250|UniProtKB:A0A218N034}. Spore membrane {ECO:0000250|UniProtKB:A0A218N034, ECO:0000255}; Multi-pass membrane protein {ECO:0000255}. Vacuole membrane {ECO:0000250|UniProtKB:A0A218N034, ECO:0000255}; Multi-pass membrane protein {ECO:0000255}. Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:A0A218N034, ECO:0000255}; Multi-pass membrane protein {ECO:0000255}. Note=Localizes in trans to all spores within an ascus. Localization to the spore vacuole is dependent on isoform 1. {ECO:0000250|UniProtKB:A0A218N034}.
| null |
TRANSMEM 104..124; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 137..157; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 167..187; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 208..228; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 233..253; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 269..289; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 296..316; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 332..352; /note="Helical"; /evidence="ECO:0000255"
|
PF03303;
|
IPR004982;
| null |
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Fungi (kingdom), Dikarya (subkingdom), Ascomycota (phylum), Taphrinomycotina (subphylum), Schizosaccharomycetes (class), Schizosaccharomycetales (order), Schizosaccharomycetaceae (family), Schizosaccharomyces (genus), Schizosaccharomyces pombe (species)
|
wtf19 SPCC1906.03
| true |
Schizosaccharomyces pombe
| 0 |
row_1246
| false | null |
166 |
O74420
|
MKNKDYPLRSSMDELSTKNDNEIDLEKGPLPEYNSEDGSTLPPYSEIWKYIKTVSEDSSTGPTEIANPNVERRQEFKDSHPNIYSLLRLLISVLAVIVVFFTAWVCVNPLEKSIFGKVAFSVTIGITCPIVFIAIFCFFETWTQAVAQCIKVTVIFLAQCVKVTAISLAQCVKVTAVFLAKCVKVTAVFLAKCVKVIAVGLYNSKKDLVVTIWLAWVVICFILFGCVKDGRLNLNKALICSTCSISAALFFILLLVCIPIWTLKHMLFGLFQVLGVQSCVVIVTKGLMYLFDKHIDATGYEIEASSLFVIGNFLFFYEMERPGALKRMPKFIGNGIASFLGGLGNAFGGIGNAFGGIGNAIGRIGNAFRGANDNNDIPLGEMDVESEV
|
Meiotic driver wtf13
|
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
| 284,812 | 388 | 42,607 |
Alternative initiation;Cytoplasm;Endoplasmic reticulum;Membrane;Reference proteome;Toxin;Transmembrane;Transmembrane helix;Vacuole
|
GO:0005737; GO:0005774; GO:0005789; GO:0072324; GO:0110134
|
Evidence at protein level
| 5 |
SUBCELLULAR LOCATION: [Isoform 1]: Spore membrane {ECO:0000255, ECO:0000269|PubMed:30475921, ECO:0000269|PubMed:32032353}; Multi-pass membrane protein {ECO:0000255}. Vacuole membrane {ECO:0000250|UniProtKB:A0A218N034, ECO:0000255}; Multi-pass membrane protein {ECO:0000255}. Note=Contained within spores expressing the isoform and localizes isoform 2 to the vacuole. {ECO:0000250|UniProtKB:A0A218N034}.; SUBCELLULAR LOCATION: [Isoform 2]: Ascus epiplasm {ECO:0000269|PubMed:30475921}. Cytoplasm {ECO:0000250|UniProtKB:A0A218N034}. Spore membrane {ECO:0000255, ECO:0000269|PubMed:30475921, ECO:0000269|PubMed:32032353}; Multi-pass membrane protein {ECO:0000255}. Vacuole membrane {ECO:0000250|UniProtKB:A0A218N034, ECO:0000255}; Multi-pass membrane protein {ECO:0000255}. Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:A0A218N034, ECO:0000255}; Multi-pass membrane protein {ECO:0000255}. Note=Localizes in trans to all spores within an ascus. Localization to the spore vacuole is dependent on isoform 1. {ECO:0000250|UniProtKB:A0A218N034}.
| null |
TRANSMEM 89..109; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 119..139; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 152..172; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 182..202; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 207..227; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 243..263; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 267..287; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 297..317; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 331..351; /note="Helical"; /evidence="ECO:0000255"
|
PF03303;
|
IPR004982;
| null |
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Fungi (kingdom), Dikarya (subkingdom), Ascomycota (phylum), Taphrinomycotina (subphylum), Schizosaccharomycetes (class), Schizosaccharomycetales (order), Schizosaccharomycetaceae (family), Schizosaccharomyces (genus), Schizosaccharomyces pombe (species)
|
wtf13 wtf12 SPCC162.04c
| true |
Schizosaccharomyces pombe
| 1 |
row_153
| false | null |
3,031 |
O94409
|
MKNKYYPLRSSMDELSAKNDNEIDLEKGPLPEYNSEDGSTLPPYSENINLKDPKQMGANNPNLFNTDESTTPPDYGEDSLSITHRENHSSGTADNSSTSPLKKAFLSFISIFVLNVPAVCYLTYKDALFKDYGKDEWVYFGVWCAICLMIFISLWYFYETWIKAVKVTVIFLAQCIKVTVVFLAQCVKVISIGLFNIRREMMIIIWLLWLIICCILFGCVKSGDLNLNKALIYSTCTISAVLLLIVSSVCIPFWTFERTLAKLAKVFLLQSGIVLVLNGTMFLRGKHFEWTGCEIEASVLFIMGNVLFLCEMECPGALIRTRNSIRNGIAFILGGIGNAMMGLANAFRGGNDNNNNIPLGEMDVEGEV
|
Meiotic driver wtf23
|
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
| 284,812 | 368 | 41,197 |
Alternative initiation;Cytoplasm;Endoplasmic reticulum;Membrane;Reference proteome;Toxin;Transmembrane;Transmembrane helix;Vacuole
|
GO:0005774; GO:0005789; GO:0005794; GO:0072324; GO:0110134
|
Inferred from homology
| 3 |
SUBCELLULAR LOCATION: [Isoform 1]: Spore membrane {ECO:0000250|UniProtKB:A0A218N034, ECO:0000255}; Multi-pass membrane protein {ECO:0000255}. Vacuole membrane {ECO:0000250|UniProtKB:A0A218N034, ECO:0000255}; Multi-pass membrane protein {ECO:0000255}. Note=Contained within spores expressing the isoform and localizes isoform 2 to the vacuole. {ECO:0000250|UniProtKB:A0A218N034}.; SUBCELLULAR LOCATION: [Isoform 2]: Ascus epiplasm {ECO:0000250|UniProtKB:A0A218N034}. Cytoplasm {ECO:0000250|UniProtKB:A0A218N034}. Spore membrane {ECO:0000250|UniProtKB:A0A218N034, ECO:0000255}; Multi-pass membrane protein {ECO:0000255}. Vacuole membrane {ECO:0000250|UniProtKB:A0A218N034, ECO:0000255}; Multi-pass membrane protein {ECO:0000255}. Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:A0A218N034, ECO:0000255}; Multi-pass membrane protein {ECO:0000255}. Note=Localizes in trans to all spores within an ascus. Localization to the spore vacuole is dependent on isoform 1. {ECO:0000250|UniProtKB:A0A218N034}.
| null |
TRANSMEM 105..124; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 139..158; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 170..192; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 202..221; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 234..256; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 266..283; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 328..350; /note="Helical"; /evidence="ECO:0000255"
|
PF03303;
|
IPR004982;
| null |
cellular organisms (no rank), Eukaryota (domain), Opisthokonta (clade), Fungi (kingdom), Dikarya (subkingdom), Ascomycota (phylum), Taphrinomycotina (subphylum), Schizosaccharomycetes (class), Schizosaccharomycetales (order), Schizosaccharomycetaceae (family), Schizosaccharomyces (genus), Schizosaccharomyces pombe (species)
|
wtf23 wtf10 SPCC1620.02
| true |
Schizosaccharomyces pombe
| 2 |
row_2930
| false | null |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.