sentence
stringlengths 9
1.35k
| relations
listlengths 1
26
| dataset
stringclasses 18
values | types
listlengths 1
24
|
---|---|---|---|
Naproxen - associated sudden sensorineural hearing loss .
|
[
{
"head": {
"name": "sudden sensorineural hearing loss",
"pos": [],
"type": ""
},
"tail": {
"name": "Naproxen",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
An amiodarone optic neuropathy has been described .
|
[
{
"head": {
"name": "optic neuropathy",
"pos": [],
"type": ""
},
"tail": {
"name": "amiodarone",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Treatment - related myelodysplastic syndrome after temozolomide for recurrent high - grade glioma .
|
[
{
"head": {
"name": "myelodysplastic syndrome",
"pos": [],
"type": ""
},
"tail": {
"name": "temozolomide",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
CONCLUSION : Significant weight loss is a potential adverse event in patients with rheumatoid arthritis treated with leflunomide .
|
[
{
"head": {
"name": "weight loss",
"pos": [],
"type": ""
},
"tail": {
"name": "leflunomide",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Hepatic angiosarcoma occurring after cyclophosphamide therapy : case report and review of the literature .
|
[
{
"head": {
"name": "Hepatic angiosarcoma",
"pos": [],
"type": ""
},
"tail": {
"name": "cyclophosphamide",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
In this report , one patient who developed gangrene after bleomycin and vincristine / vinblastine chemotherapy for AIDS - related Kaposi 's sarcoma and another HIV - infected patient who exhibited symptoms of severe Raynaud 's phenomenon related to the same regimen are presented .
|
[
{
"head": {
"name": "gangrene",
"pos": [],
"type": ""
},
"tail": {
"name": "bleomycin",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "gangrene",
"pos": [],
"type": ""
},
"tail": {
"name": "vinblastine",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "gangrene",
"pos": [],
"type": ""
},
"tail": {
"name": "vincristine",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "severe Raynaud 's phenomenon",
"pos": [],
"type": ""
},
"tail": {
"name": "bleomycin",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "severe Raynaud 's phenomenon",
"pos": [],
"type": ""
},
"tail": {
"name": "vinblastine",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "severe Raynaud 's phenomenon",
"pos": [],
"type": ""
},
"tail": {
"name": "vincristine",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Carbamazepine - induced tics .
|
[
{
"head": {
"name": "tics",
"pos": [],
"type": ""
},
"tail": {
"name": "Carbamazepine",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Successful recovery from interstitial pneumonitis , induced by bicalutamide and leuprorelin acetate given as treatment for prostate cancer .
|
[
{
"head": {
"name": "interstitial pneumonitis",
"pos": [],
"type": ""
},
"tail": {
"name": "bicalutamide",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "interstitial pneumonitis",
"pos": [],
"type": ""
},
"tail": {
"name": "leuprorelin acetate",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Levofloxacin - induced toxic epidermal necrolysis in an elderly patient .
|
[
{
"head": {
"name": "toxic epidermal necrolysis",
"pos": [],
"type": ""
},
"tail": {
"name": "Levofloxacin",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
We describe 2 male patients , a 49-year - old with psoriatic arthritis and impaired renal function and a 43-year - old renal transplant recipient , who both sustained a marked decline in glomerular filtration rate in conjunction with a selective inhibitor of cyclooxygenase-2 ( COX-2 ) , rofecoxib .
|
[
{
"head": {
"name": "decline in glomerular filtration rate",
"pos": [],
"type": ""
},
"tail": {
"name": "rofecoxib",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
The biochemistry of paracetamol hepatotoxicity is outlined and the increased susceptibility of alcoholic patients to the hepatotoxic effects of paracetamol is remarked upon .
|
[
{
"head": {
"name": "hepatotoxic effects",
"pos": [],
"type": ""
},
"tail": {
"name": "paracetamol",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "hepatotoxicity",
"pos": [],
"type": ""
},
"tail": {
"name": "paracetamol",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Tenofovir - associated nephrotoxicity in two HIV - infected adolescent males .
|
[
{
"head": {
"name": "nephrotoxicity",
"pos": [],
"type": ""
},
"tail": {
"name": "Tenofovir",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Based on the Naranjo probability scale , serotonin syndrome was a probable adverse reaction associated with co - administration of citalopram and fentanyl .
|
[
{
"head": {
"name": "serotonin syndrome",
"pos": [],
"type": ""
},
"tail": {
"name": "citalopram",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "serotonin syndrome",
"pos": [],
"type": ""
},
"tail": {
"name": "fentanyl",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
This supports the well - reported potential of bleomycin to trigger acral vascular toxicity .
|
[
{
"head": {
"name": "acral vascular toxicity",
"pos": [],
"type": ""
},
"tail": {
"name": "bleomycin",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Because of serious side effects of an increase in the QT interval causing torsades de pointes , dofetilide must be initiated with close monitoring of the QT interval in an inpatient setting .
|
[
{
"head": {
"name": "increase in the QT interval",
"pos": [],
"type": ""
},
"tail": {
"name": "dofetilide",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "torsades de pointes",
"pos": [],
"type": ""
},
"tail": {
"name": "dofetilide",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Development of Crohn 's disease in a patient with multiple sclerosis treated with copaxone .
|
[
{
"head": {
"name": "Crohn 's disease",
"pos": [],
"type": ""
},
"tail": {
"name": "copaxone",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
CONCLUSIONS : This patient 's rhabdomyolysis was probably induced by sertraline therapy .
|
[
{
"head": {
"name": "rhabdomyolysis",
"pos": [],
"type": ""
},
"tail": {
"name": "sertraline",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
PURPOSE : To present a case of respiratory depression following the administration of nebulised morphine .
|
[
{
"head": {
"name": "respiratory depression",
"pos": [],
"type": ""
},
"tail": {
"name": "morphine",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
INTRODUCTION : Although gefitinib used for the treatment of non - small - cell lung cancer is a well - known cause of interstitial lung disease ( ILD ) , few case reports on erlotinib - induced ILD have been issued .
|
[
{
"head": {
"name": "ILD",
"pos": [],
"type": ""
},
"tail": {
"name": "gefitinib",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "ILD",
"pos": [],
"type": ""
},
"tail": {
"name": "erlotinib",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "interstitial lung disease",
"pos": [],
"type": ""
},
"tail": {
"name": "gefitinib",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Captopril - related ( and -induced ? ) asthma .
|
[
{
"head": {
"name": "asthma",
"pos": [],
"type": ""
},
"tail": {
"name": "Captopril",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
We present the case of a 5-year - old girl who developed bilateral vocal cord paralysis following preoperative peritonsillar bupivacaine infiltration .
|
[
{
"head": {
"name": "bilateral vocal cord paralysis",
"pos": [],
"type": ""
},
"tail": {
"name": "bupivacaine",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
We describe a case of fibrosing alveolitis , diagnosed by lung biopsy , in a patient receiving amiodarone which responded to corticosteroid therapy .
|
[
{
"head": {
"name": "fibrosing alveolitis",
"pos": [],
"type": ""
},
"tail": {
"name": "amiodarone",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
An unusual presentation of spontaneous sub - conjunctival haematoma in a patient receiving warfarin .
|
[
{
"head": {
"name": "sub - conjunctival haematoma",
"pos": [],
"type": ""
},
"tail": {
"name": "warfarin",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
This case study describes an atypical case of refractory , sodium warfarin - induced necrotizing fasciitis and myonecrosis .
|
[
{
"head": {
"name": "myonecrosis",
"pos": [],
"type": ""
},
"tail": {
"name": "sodium warfarin",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "necrotizing fasciitis",
"pos": [],
"type": ""
},
"tail": {
"name": "sodium warfarin",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
A case of noncardiogenic pulmonary edema by ethanolamine oleate .
|
[
{
"head": {
"name": "noncardiogenic pulmonary edema",
"pos": [],
"type": ""
},
"tail": {
"name": "ethanolamine oleate",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
The azathioprine dose was low ( 1 mg / kg ) and pancytopenia occurred after 56 days therapy .
|
[
{
"head": {
"name": "pancytopenia",
"pos": [],
"type": ""
},
"tail": {
"name": "azathioprine",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
A girl with cystic fibrosis and cyclic neutropenia developed an erythematous papular eruption without fever or neutrophilia 7 months after commencing therapy with G - CSF .
|
[
{
"head": {
"name": "erythematous papular eruption",
"pos": [],
"type": ""
},
"tail": {
"name": "G - CSF",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Although vasculitis has been reported in the course of hairy cell leukaemia , it has only rarely been reported as the consequence of cladribine treatment .
|
[
{
"head": {
"name": "vasculitis",
"pos": [],
"type": ""
},
"tail": {
"name": "cladribine",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Cerebrovascular complications of L - asparaginase therapy in children with leukemia : aphasia and other neuropsychological deficits .
|
[
{
"head": {
"name": "aphasia",
"pos": [],
"type": ""
},
"tail": {
"name": "L - asparaginase",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "Cerebrovascular complications",
"pos": [],
"type": ""
},
"tail": {
"name": "L - asparaginase",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "neuropsychological deficits",
"pos": [],
"type": ""
},
"tail": {
"name": "L - asparaginase",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
We report a case of acute hyperphosphatemia secondary to rectal administration of sodium phosphate and sodium biphosphate ( Fleet enema ) .
|
[
{
"head": {
"name": "hyperphosphatemia",
"pos": [],
"type": ""
},
"tail": {
"name": "sodium biphosphate",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "hyperphosphatemia",
"pos": [],
"type": ""
},
"tail": {
"name": "sodium phosphate",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Cardiac hypersensitivity and myopericarditis have been reported during long - term treatment with mesalazine .
|
[
{
"head": {
"name": "Cardiac hypersensitivity",
"pos": [],
"type": ""
},
"tail": {
"name": "mesalazine",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "myopericarditis",
"pos": [],
"type": ""
},
"tail": {
"name": "mesalazine",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
It carries a well - known risk of neutropenia and agranulocytosis , which necessitates the immediate discontinuation of clozapine .
|
[
{
"head": {
"name": "agranulocytosis",
"pos": [],
"type": ""
},
"tail": {
"name": "clozapine",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "neutropenia",
"pos": [],
"type": ""
},
"tail": {
"name": "clozapine",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Pemphigus foliaceus was seen in a patient with pulmonary tuberculosis during rifampicin therapy .
|
[
{
"head": {
"name": "Pemphigus foliaceus",
"pos": [],
"type": ""
},
"tail": {
"name": "rifampicin",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
a 67-year - old man with bipolar disorder developed a Creutzfeldt - Jakob like syndrome during lithium carbonate treatment .
|
[
{
"head": {
"name": "Creutzfeldt - Jakob like syndrome",
"pos": [],
"type": ""
},
"tail": {
"name": "lithium carbonate",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Physicians should therefore be aware of its occurrence and carefully monitor serum levels of CPK , GOT and GPT during the treatment of diabetes insipidus with clofibrate , especially in patients with associated hypothyroidism , latent or overt , which possibly favors the development of myopathy .
|
[
{
"head": {
"name": "myopathy",
"pos": [],
"type": ""
},
"tail": {
"name": "clofibrate",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
An insulin - dependent diabetic patient with nephropathy developed severe acidosis after treatment with acetazolamide for glaucoma .
|
[
{
"head": {
"name": "severe acidosis",
"pos": [],
"type": ""
},
"tail": {
"name": "acetazolamide",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
The day after clozapine was stopped , while he was still receiving clomipramine 150 mg / d , he began behaving oddly , started sweating profusely , shivering , and became tremulous , agitated , and confused .
|
[
{
"head": {
"name": "agitated",
"pos": [],
"type": ""
},
"tail": {
"name": "clomipramine",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "agitated",
"pos": [],
"type": ""
},
"tail": {
"name": "clozapine",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "behaving oddly",
"pos": [],
"type": ""
},
"tail": {
"name": "clomipramine",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "behaving oddly",
"pos": [],
"type": ""
},
"tail": {
"name": "clozapine",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "confused",
"pos": [],
"type": ""
},
"tail": {
"name": "clomipramine",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "confused",
"pos": [],
"type": ""
},
"tail": {
"name": "clozapine",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "shivering",
"pos": [],
"type": ""
},
"tail": {
"name": "clomipramine",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "shivering",
"pos": [],
"type": ""
},
"tail": {
"name": "clozapine",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "sweating profusely",
"pos": [],
"type": ""
},
"tail": {
"name": "clomipramine",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "sweating profusely",
"pos": [],
"type": ""
},
"tail": {
"name": "clozapine",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "tremulous",
"pos": [],
"type": ""
},
"tail": {
"name": "clomipramine",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "tremulous",
"pos": [],
"type": ""
},
"tail": {
"name": "clozapine",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Moreover , these findings suggest that the incidence of BOOP following rituximab therapy may be higher than has been previously appreciated .
|
[
{
"head": {
"name": "BOOP",
"pos": [],
"type": ""
},
"tail": {
"name": "rituximab",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
A teenage girl with crescentic glomerulonephritis had antineutrophil cytoplasmic antibody ( ANCA ) detected after she had received propylthiouracil ( PTU ) for hyperthyroidism without cutaneous vasculitis .
|
[
{
"head": {
"name": "antineutrophil cytoplasmic antibody",
"pos": [],
"type": ""
},
"tail": {
"name": "propylthiouracil",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "antineutrophil cytoplasmic antibody",
"pos": [],
"type": ""
},
"tail": {
"name": "PTU",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
We report a 44-year - old woman with t - MDS ( refractory anemia with excess blasts ) following treatment of recurrent anaplastic astrocytoma with temozolomide ( TMZ ) .
|
[
{
"head": {
"name": "refractory anemia with excess blasts",
"pos": [],
"type": ""
},
"tail": {
"name": "temozolomide",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "refractory anemia with excess blasts",
"pos": [],
"type": ""
},
"tail": {
"name": "TMZ",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Cushing 's syndrome persisted more than 6 months while TCA concentrations remained detectable for at least 80 days .
|
[
{
"head": {
"name": "Cushing 's syndrome",
"pos": [],
"type": ""
},
"tail": {
"name": "TCA",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Severe adenovirus pneumonia ( AVP ) following infliximab infusion for the treatment of Crohn 's disease .
|
[
{
"head": {
"name": "AVP",
"pos": [],
"type": ""
},
"tail": {
"name": "infliximab",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "Severe adenovirus pneumonia",
"pos": [],
"type": ""
},
"tail": {
"name": "infliximab",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
The disease - modifying drugs he was taking , cyclosporin and methotrexate , were stopped , and the lymphoma resolved spontaneously without the use of chemotherapy .
|
[
{
"head": {
"name": "lymphoma",
"pos": [],
"type": ""
},
"tail": {
"name": "cyclosporin",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "lymphoma",
"pos": [],
"type": ""
},
"tail": {
"name": "methotrexate",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Leflunomide - associated weight loss in rheumatoid arthritis .
|
[
{
"head": {
"name": "weight loss",
"pos": [],
"type": ""
},
"tail": {
"name": "Leflunomide",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Several cases of lithium - induced Creutzfeldt - Jakob syndrome have been reported to date ; all of them were elderly patients and a half had " therapeutic " lithium serum levels .
|
[
{
"head": {
"name": "Creutzfeldt - Jakob syndrome",
"pos": [],
"type": ""
},
"tail": {
"name": "lithium",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "Creutzfeldt - Jakob syndrome",
"pos": [],
"type": ""
},
"tail": {
"name": "lithium",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Milk - alkali syndrome induced by 1,25(OH)2D in a patient with hypoparathyroidism .
|
[
{
"head": {
"name": "Milk - alkali syndrome",
"pos": [],
"type": ""
},
"tail": {
"name": "1,25(OH)2D",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
However , because diphenhydramine also exhibits type IA sodium channel blockade , cardiac toxicity is also possible .
|
[
{
"head": {
"name": "cardiac toxicity",
"pos": [],
"type": ""
},
"tail": {
"name": "diphenhydramine",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
OBJECTIVE : To report a case of serotonin syndrome associated with interaction between fentanyl and citalopram , as evidenced by medication history , clinical features and reversal following discontinuation of fentanyl .
|
[
{
"head": {
"name": "serotonin syndrome",
"pos": [],
"type": ""
},
"tail": {
"name": "citalopram",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "serotonin syndrome",
"pos": [],
"type": ""
},
"tail": {
"name": "fentanyl",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "serotonin syndrome",
"pos": [],
"type": ""
},
"tail": {
"name": "fentanyl",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
We report two cases of neutropenia following captopril use in cardiac patients with trisomy 21 .
|
[
{
"head": {
"name": "neutropenia",
"pos": [],
"type": ""
},
"tail": {
"name": "captopril",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Propafenone - induced ataxia : report of three cases .
|
[
{
"head": {
"name": "ataxia",
"pos": [],
"type": ""
},
"tail": {
"name": "Propafenone",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
This article reports the case of an otherwise healthy patient who experienced permanent sensorineural hearing loss after a brief course of naproxen and reviews the literature on NSAID - related permanent sensorineural hearing loss .
|
[
{
"head": {
"name": "sensorineural hearing loss",
"pos": [],
"type": ""
},
"tail": {
"name": "naproxen",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Potential causes of methamphetamine - related keratitis can be divided into four categories resulting from ( a ) direct pharmacologic and physical effects of methamphetamine ; ( b ) the toxic effects of diluting or " cutting " agents such as lidocaine and quinine ; ( c ) effects related to the route of drug administration ( intravenous , inhalation , smoking ) ; and ( d ) manufacture - related effects of exposure to unintentional caustic contaminants in the final product .
|
[
{
"head": {
"name": "keratitis",
"pos": [],
"type": ""
},
"tail": {
"name": "lidocaine",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "keratitis",
"pos": [],
"type": ""
},
"tail": {
"name": "methamphetamine",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "keratitis",
"pos": [],
"type": ""
},
"tail": {
"name": "quinine",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "toxic effects",
"pos": [],
"type": ""
},
"tail": {
"name": "lidocaine",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "toxic effects",
"pos": [],
"type": ""
},
"tail": {
"name": "methamphetamine",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "toxic effects",
"pos": [],
"type": ""
},
"tail": {
"name": "quinine",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Lymphoma developing in a patient with rheumatoid arthritis taking methotrexate .
|
[
{
"head": {
"name": "Lymphoma",
"pos": [],
"type": ""
},
"tail": {
"name": "methotrexate",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Contact dermatitis due to budesonide : report of five cases and review of the Japanese literature .
|
[
{
"head": {
"name": "Contact dermatitis",
"pos": [],
"type": ""
},
"tail": {
"name": "budesonide",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Herein we report four patients who underwent liver transplantation and developed neutropenia while receiving MMF .
|
[
{
"head": {
"name": "neutropenia",
"pos": [],
"type": ""
},
"tail": {
"name": "MMF",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Accordingly , camptocormia is a dose - dependent side effect of valproate .
|
[
{
"head": {
"name": "camptocormia",
"pos": [],
"type": ""
},
"tail": {
"name": "valproate",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Myoglobinuria and acute renal failure were observed in two patients with vasopressin - treated gastrointestinal hemorrhage .
|
[
{
"head": {
"name": "acute renal failure",
"pos": [],
"type": ""
},
"tail": {
"name": "vasopressin",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "Myoglobinuria",
"pos": [],
"type": ""
},
"tail": {
"name": "vasopressin",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Carbamazepine - induced systemic lupus erythematosus - like disease .
|
[
{
"head": {
"name": "systemic lupus erythematosus - like disease",
"pos": [],
"type": ""
},
"tail": {
"name": "Carbamazepine",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Acute eosinophilic pneumonia caused by calcium stearate , an additive agent for an oral antihistaminic medication .
|
[
{
"head": {
"name": "Acute eosinophilic pneumonia",
"pos": [],
"type": ""
},
"tail": {
"name": "calcium stearate",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
This report suggests that anemia can occur due to MMF , in particular when it is given with prednisone , a side effect well documented in the transplantation literature when the triple combination of MMF , cyclosporine and prednisone is used .
|
[
{
"head": {
"name": "anemia",
"pos": [],
"type": ""
},
"tail": {
"name": "cyclosporine",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "anemia",
"pos": [],
"type": ""
},
"tail": {
"name": "MMF",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "anemia",
"pos": [],
"type": ""
},
"tail": {
"name": "MMF",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "anemia",
"pos": [],
"type": ""
},
"tail": {
"name": "prednisone",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "anemia",
"pos": [],
"type": ""
},
"tail": {
"name": "prednisone",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
FK506 , which began to be administered 12 days earlier , rose to a level of 44 ng / mL ( normal range , 10 - 20 ng / mL ) 1 day before neurologic abnormalities began .
|
[
{
"head": {
"name": "neurologic abnormalities",
"pos": [],
"type": ""
},
"tail": {
"name": "FK506",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
We believe that these skin eruptions belong to a spectrum of neutrophilic dermatoses that can be induced or aggravated by G - CSF therapy .
|
[
{
"head": {
"name": "neutrophilic dermatoses",
"pos": [],
"type": ""
},
"tail": {
"name": "G - CSF",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "skin eruptions",
"pos": [],
"type": ""
},
"tail": {
"name": "G - CSF",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Metamizole , a nonsteroidal antiinflammatory agent , is prohibited in the United States because of the risk of agranulocytosis but is widely used in Mexico and other countries .
|
[
{
"head": {
"name": "agranulocytosis",
"pos": [],
"type": ""
},
"tail": {
"name": "Metamizole",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Albendazole - induced pseudomembranous colitis .
|
[
{
"head": {
"name": "pseudomembranous colitis",
"pos": [],
"type": ""
},
"tail": {
"name": "Albendazole",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
In this paper we report a case of nimodipine overdosage resulting in prolonged hypotension and hypoxemia , which was successfully treated with calcium gluconate .
|
[
{
"head": {
"name": "hypoxemia",
"pos": [],
"type": ""
},
"tail": {
"name": "nimodipine",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "prolonged hypotension",
"pos": [],
"type": ""
},
"tail": {
"name": "nimodipine",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
This case suggests the importance of careful observation for extramedullary relapse in patients who are treated with ATRA .
|
[
{
"head": {
"name": "extramedullary relapse",
"pos": [],
"type": ""
},
"tail": {
"name": "ATRA",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Suspected ciprofloxacin - induced interstitial nephritis .
|
[
{
"head": {
"name": "interstitial nephritis",
"pos": [],
"type": ""
},
"tail": {
"name": "ciprofloxacin",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Other thiazolidinediones currently in clinical trials may be able to provide the therapeutic benefits of troglitazone without significant hepatotoxicity .
|
[
{
"head": {
"name": "hepatotoxicity",
"pos": [],
"type": ""
},
"tail": {
"name": "troglitazone",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
We report ( to our knowledge , for the first time in a child ) the emergence of psychosis in a 12-year old white girl with an increased efavirenz concentration and heterozygous gene polymorphism of the CYP2B6-G516 T .
|
[
{
"head": {
"name": "psychosis",
"pos": [],
"type": ""
},
"tail": {
"name": "efavirenz",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
The mechanism of the decrease in plasma potassium induced by phosphate treatment was investigated in a 24-year - old hypertensive patient with hypophosphatemic osteomalacia , who was the youngest of four patients , belonging to a 23 number kindred of five generations .
|
[
{
"head": {
"name": "decrease in plasma potassium",
"pos": [],
"type": ""
},
"tail": {
"name": "phosphate",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
We report a case of reversible encephalopathy syndrome in a 16-year - old girl with acute myelogenous leukemia ( AML ) , who is undergoing during consolidation chemotherapy composed of BH - AC ( N4-behenoyl-1-beta - D - arabinofuranosyl cytosine ) and idarubicin .
|
[
{
"head": {
"name": "encephalopathy syndrome",
"pos": [],
"type": ""
},
"tail": {
"name": "BH - AC",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "encephalopathy syndrome",
"pos": [],
"type": ""
},
"tail": {
"name": "idarubicin",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Papillary necrosis associated with the HIV protease inhibitor indinavir .
|
[
{
"head": {
"name": "Papillary necrosis",
"pos": [],
"type": ""
},
"tail": {
"name": "indinavir",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Interstitial granulomatous dermatitis associated with darifenacin .
|
[
{
"head": {
"name": "Interstitial granulomatous dermatitis",
"pos": [],
"type": ""
},
"tail": {
"name": "darifenacin",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
METHODS : Growth retardation was observed in six severely asthmatic children after introduction of high - dose fluticasone propionate treatment ( dry powder ) .
|
[
{
"head": {
"name": "Growth retardation",
"pos": [],
"type": ""
},
"tail": {
"name": "fluticasone propionate",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
The ampicillin rash occurring in cases of infectious mononucleosis is well documented .
|
[
{
"head": {
"name": "ampicillin rash",
"pos": [],
"type": ""
},
"tail": {
"name": "ampicillin",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Although useful in the management of chronic alcoholism , disulfiram is being increasingly associated with a wide spectrum of side effects and untoward medical sequelae , which now include catatonia .
|
[
{
"head": {
"name": "catatonia",
"pos": [],
"type": ""
},
"tail": {
"name": "disulfiram",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
These are the first reported patients to show mfERG abnormalities that correspond to bitemporal visual field defects and add to the growing evidence that ethambutol damages the retina .
|
[
{
"head": {
"name": "bitemporal visual field defects",
"pos": [],
"type": ""
},
"tail": {
"name": "ethambutol",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "mfERG abnormalities",
"pos": [],
"type": ""
},
"tail": {
"name": "ethambutol",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Mycophenolate mofetil - induced neutropenia in liver transplantation .
|
[
{
"head": {
"name": "neutropenia",
"pos": [],
"type": ""
},
"tail": {
"name": "Mycophenolate mofetil",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Progressive pulmonary fibrosis complicating cyclophosphamide therapy .
|
[
{
"head": {
"name": "Progressive pulmonary fibrosis",
"pos": [],
"type": ""
},
"tail": {
"name": "cyclophosphamide",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Drug - induced mammary hyperplasias have been reported as rare complications of D - penicillamine and Neothetazone .
|
[
{
"head": {
"name": "mammary hyperplasias",
"pos": [],
"type": ""
},
"tail": {
"name": "D - penicillamine",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "mammary hyperplasias",
"pos": [],
"type": ""
},
"tail": {
"name": "Neothetazone",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
She was treated with acyclovir and subsequently developed VZV antigen - positive zoster .
|
[
{
"head": {
"name": "VZV antigen - positive zoster",
"pos": [],
"type": ""
},
"tail": {
"name": "acyclovir",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
RESULTS : All cases developed corneal endothelial deposits after previous use of rifabutin .
|
[
{
"head": {
"name": "corneal endothelial deposits",
"pos": [],
"type": ""
},
"tail": {
"name": "rifabutin",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
OBJECTIVE : The purpose of this study was to determine whether desensitization to NPH insulin , as well as standard insulin desensitization , could control allergic symptoms in a patient allergic to both NPH and regular insulin .
|
[
{
"head": {
"name": "allergic symptoms",
"pos": [],
"type": ""
},
"tail": {
"name": "insulin",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "allergic symptoms",
"pos": [],
"type": ""
},
"tail": {
"name": "NPH insulin",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
We present a case of acute epinephrine toxicity resulting in acute myocardial ischemia in a young boy with combined variable immunodeficiency syndrome who developed severe allergic reaction to intravenous immunoglobulin , and was subsequently given epinephrine by mistake intravenously rather than subcutaneously .
|
[
{
"head": {
"name": "acute myocardial ischemia",
"pos": [],
"type": ""
},
"tail": {
"name": "epinephrine",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "severe allergic reaction",
"pos": [],
"type": ""
},
"tail": {
"name": "epinephrine",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "severe allergic reaction",
"pos": [],
"type": ""
},
"tail": {
"name": "epinephrine",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Dipyrone , also known as metamizole , is an analgesic and antipyretic drug that was banned by the United States Food and Drug Administration because of its association with agranulocytosis .
|
[
{
"head": {
"name": "agranulocytosis",
"pos": [],
"type": ""
},
"tail": {
"name": "Dipyrone",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "agranulocytosis",
"pos": [],
"type": ""
},
"tail": {
"name": "metamizole",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Prolonged used of hydroxyurea in patients with ET may lead to therapy - associated acute leukemia .
|
[
{
"head": {
"name": "acute leukemia",
"pos": [],
"type": ""
},
"tail": {
"name": "hydroxyurea",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Carbamazepine - induced hyperammonemia .
|
[
{
"head": {
"name": "hyperammonemia",
"pos": [],
"type": ""
},
"tail": {
"name": "Carbamazepine",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
OBJECTIVE : To document a case of serotonin syndrome ( SS ) associated with mirtazapine monotherapy , review the previously reported cases of SS associated with this tetracyclic antidepressant , and discuss the possible pathogenic mechanisms leading to this serious adverse drug reaction .
|
[
{
"head": {
"name": "serotonin syndrome",
"pos": [],
"type": ""
},
"tail": {
"name": "mirtazapine",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "SS",
"pos": [],
"type": ""
},
"tail": {
"name": "mirtazapine",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
The delayed encephalopathy developed 9 and 22 months respectively after the first dose of intrathecal methotrexate .
|
[
{
"head": {
"name": "encephalopathy",
"pos": [],
"type": ""
},
"tail": {
"name": "methotrexate",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
We believe that the acute renal failure in our patient was associated with anastrozole .
|
[
{
"head": {
"name": "acute renal failure",
"pos": [],
"type": ""
},
"tail": {
"name": "anastrozole",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Parenteral - verapamil - induced sustained hypotension .
|
[
{
"head": {
"name": "sustained hypotension",
"pos": [],
"type": ""
},
"tail": {
"name": "verapamil",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Piloerection induced by replacing fluvoxamine with milnacipran .
|
[
{
"head": {
"name": "Piloerection",
"pos": [],
"type": ""
},
"tail": {
"name": "fluvoxamine",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "Piloerection",
"pos": [],
"type": ""
},
"tail": {
"name": "milnacipran",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Sodium valproate and carbamazepine , antiepileptic drugs that are associated with a relatively low rate of adverse cutaneous reactions , should be added to the growing list of drugs that produce psoriasiform eruptions .
|
[
{
"head": {
"name": "psoriasiform eruptions",
"pos": [],
"type": ""
},
"tail": {
"name": "carbamazepine",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "psoriasiform eruptions",
"pos": [],
"type": ""
},
"tail": {
"name": "Sodium valproate",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
In each of the three reported patients , alteration of eyelid appearance with deepening of the lid sulcus was evident as the result of topical bimatoprost therapy .
|
[
{
"head": {
"name": "alteration of eyelid appearance",
"pos": [],
"type": ""
},
"tail": {
"name": "bimatoprost",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "deepening of the lid sulcus",
"pos": [],
"type": ""
},
"tail": {
"name": "bimatoprost",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
We highlight two instances of systemic allergic reaction , and discuss the potential side effects of local aprotinin injections in the orthopaedic setting as well as the evidence base for its use .
|
[
{
"head": {
"name": "systemic allergic reaction",
"pos": [],
"type": ""
},
"tail": {
"name": "aprotinin",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Five patients receiving fluoxetine for the treatment of obsessive compulsive disorder or major depression developed akathisia .
|
[
{
"head": {
"name": "akathisia",
"pos": [],
"type": ""
},
"tail": {
"name": "fluoxetine",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
We report the case of a 14-year - old female with acute promyelocytic leukemia who developed symptomatic cardiomyopathy only 4 months into treatment with a combination of daunomycin and all - trans retinoic acid ( ATRA ) .
|
[
{
"head": {
"name": "symptomatic cardiomyopathy",
"pos": [],
"type": ""
},
"tail": {
"name": "all - trans retinoic acid",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "symptomatic cardiomyopathy",
"pos": [],
"type": ""
},
"tail": {
"name": "ATRA",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "symptomatic cardiomyopathy",
"pos": [],
"type": ""
},
"tail": {
"name": "daunomycin",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Protamine - induced fatal anaphylaxis .
|
[
{
"head": {
"name": "fatal anaphylaxis",
"pos": [],
"type": ""
},
"tail": {
"name": "Protamine",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Liver disease induced by perhexiline maleate .
|
[
{
"head": {
"name": "Liver disease",
"pos": [],
"type": ""
},
"tail": {
"name": "perhexiline maleate",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
So far , few cases of pulmonary side effects caused by ticlopidine have been reported .
|
[
{
"head": {
"name": "pulmonary side effects",
"pos": [],
"type": ""
},
"tail": {
"name": "ticlopidine",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
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