sentence
stringlengths 9
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| relations
listlengths 1
26
| dataset
stringclasses 18
values | types
listlengths 1
24
|
|---|---|---|---|
We reviewed the literature in an attempt to characterize the pattern and predictors of TMP / SMX - induced aseptic meningitis .
|
[
{
"head": {
"name": "aseptic meningitis",
"pos": [],
"type": ""
},
"tail": {
"name": "SMX",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "aseptic meningitis",
"pos": [],
"type": ""
},
"tail": {
"name": "TMP",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Combining methylephedrine and Chinese herbal drugs might carry a risk of stroke .
|
[
{
"head": {
"name": "stroke",
"pos": [],
"type": ""
},
"tail": {
"name": "methylephedrine",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Red blood cell anemia in a patient with pemphigus vulgaris induced by the use of mycophenolate mofetil and prednisone .
|
[
{
"head": {
"name": "Red blood cell anemia",
"pos": [],
"type": ""
},
"tail": {
"name": "mycophenolate mofetil",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "Red blood cell anemia",
"pos": [],
"type": ""
},
"tail": {
"name": "prednisone",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
We report the case of a 43-year - old man with ITP refractory to steroids and intravenous immunoglobulin who developed acute respiratory distress syndrome ( ARDS ) after a single infusion of rituximab .
|
[
{
"head": {
"name": "acute respiratory distress syndrome",
"pos": [],
"type": ""
},
"tail": {
"name": "rituximab",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "ARDS",
"pos": [],
"type": ""
},
"tail": {
"name": "rituximab",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Although other nitrites induce methemoglobinemia , exposure to methyl nitrite during phenylpropanolamine production appears to be a new cause of occupational methemoglobinemia .
|
[
{
"head": {
"name": "methemoglobinemia",
"pos": [],
"type": ""
},
"tail": {
"name": "methyl nitrite",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "methemoglobinemia",
"pos": [],
"type": ""
},
"tail": {
"name": "methyl nitrite",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Upper gastrointestinal haemorrhage is a serious complication of aspirin and clopidogrel ( dual ) anti - platelet therapy with a high morbidity and mortality .
|
[
{
"head": {
"name": "Upper gastrointestinal haemorrhage",
"pos": [],
"type": ""
},
"tail": {
"name": "aspirin",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "Upper gastrointestinal haemorrhage",
"pos": [],
"type": ""
},
"tail": {
"name": "clopidogrel",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Visual hallucinations associated with zonisamide .
|
[
{
"head": {
"name": "Visual hallucinations",
"pos": [],
"type": ""
},
"tail": {
"name": "zonisamide",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Several case reports of aplastic anemia with use of acetazolamide , and two cases with use of methazolamide , have appeared in the literature .
|
[
{
"head": {
"name": "aplastic anemia",
"pos": [],
"type": ""
},
"tail": {
"name": "acetazolamide",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "aplastic anemia",
"pos": [],
"type": ""
},
"tail": {
"name": "methazolamide",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
The increasing prevalence of methamphetamine abuse and the severity of the associated ulcers should alert ophthalmologists to the problem of methamphetamine - related keratitis .
|
[
{
"head": {
"name": "keratitis",
"pos": [],
"type": ""
},
"tail": {
"name": "methamphetamine",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "ulcers",
"pos": [],
"type": ""
},
"tail": {
"name": "methamphetamine",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
The clinical course suggests that caffeine , which is present in oolong tea , was mainly responsible for the rhabdomyolysis as well as the delirium , although severe hyponatremia has been reported to cause rhabdomyolysis on rare occasions .
|
[
{
"head": {
"name": "delirium",
"pos": [],
"type": ""
},
"tail": {
"name": "caffeine",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "hyponatremia",
"pos": [],
"type": ""
},
"tail": {
"name": "caffeine",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "rhabdomyolysis",
"pos": [],
"type": ""
},
"tail": {
"name": "caffeine",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "rhabdomyolysis",
"pos": [],
"type": ""
},
"tail": {
"name": "caffeine",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Secretory endometrial adenocarcinoma in a patient on tamoxifen for breast cancer : a report of a case .
|
[
{
"head": {
"name": "Secretory endometrial adenocarcinoma",
"pos": [],
"type": ""
},
"tail": {
"name": "tamoxifen",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
A female patient with HER2 positive , metastatic breast cancer presented with pulmonary infiltrates , and a plural effusion dyspnoea after several months of trastuzumab treatment .
|
[
{
"head": {
"name": "plural effusion dyspnoea",
"pos": [],
"type": ""
},
"tail": {
"name": "trastuzumab",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "pulmonary infiltrates",
"pos": [],
"type": ""
},
"tail": {
"name": "trastuzumab",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Hypoxemia improved during continuous tolazoline infusion , but gastrointestinal bleeding occurred .
|
[
{
"head": {
"name": "gastrointestinal bleeding",
"pos": [],
"type": ""
},
"tail": {
"name": "tolazoline",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
We present here a female patient who developed acute bilateral parotitis within minutes of i.v . enalaprilat injection and recovered within 24 hours of stopping the drug and with symptomatic treatment .
|
[
{
"head": {
"name": "acute bilateral parotitis",
"pos": [],
"type": ""
},
"tail": {
"name": "enalaprilat",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
She had been on Copaxone 20 mg / day treatment for 2 years when she first exhibited gastrointestinal symptoms .
|
[
{
"head": {
"name": "gastrointestinal symptoms",
"pos": [],
"type": ""
},
"tail": {
"name": "Copaxone",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Priapism associated with trazodone therapy : case report .
|
[
{
"head": {
"name": "Priapism",
"pos": [],
"type": ""
},
"tail": {
"name": "trazodone",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Case 3 : A 29-year - old female alcoholic complained of general fatigue and a slight fever after 1.5 years of abstinence with cyanamide treatment .
|
[
{
"head": {
"name": "fatigue",
"pos": [],
"type": ""
},
"tail": {
"name": "cyanamide",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "fever",
"pos": [],
"type": ""
},
"tail": {
"name": "cyanamide",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
A wide variety of adverse central nervous system effects have been reported in association with propafenone ; dizziness is the most common .
|
[
{
"head": {
"name": "adverse central nervous system effects",
"pos": [],
"type": ""
},
"tail": {
"name": "propafenone",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "dizziness",
"pos": [],
"type": ""
},
"tail": {
"name": "propafenone",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Given that discontinuation of nitrofurantoin and introduction of methylprednisolon therapy significantly lowered liver enzyme levels , restoring most of them to normal , we concluded that this was probably the case of toxic liver damage caused by nitrofurantoin .
|
[
{
"head": {
"name": "toxic liver damage",
"pos": [],
"type": ""
},
"tail": {
"name": "nitrofurantoin",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Risperidone withdrawal - related respiratory dyskinesia : a case diagnosed by spirography and fibroscopy .
|
[
{
"head": {
"name": "respiratory dyskinesia",
"pos": [],
"type": ""
},
"tail": {
"name": "Risperidone",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
With the first cyclosporine dose , the patient complained of leg pain that was most severe during the cyclosporine infusion .
|
[
{
"head": {
"name": "leg pain",
"pos": [],
"type": ""
},
"tail": {
"name": "cyclosporine",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "leg pain",
"pos": [],
"type": ""
},
"tail": {
"name": "cyclosporine",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Ezetimibe - induced acute pancreatitis .
|
[
{
"head": {
"name": "acute pancreatitis",
"pos": [],
"type": ""
},
"tail": {
"name": "Ezetimibe",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
In this study , we report on three individual patients who received BTX - B and who subsequently developed parasympathetic dysfunction of the visual system after injections of BTX - B at remote sites .
|
[
{
"head": {
"name": "parasympathetic dysfunction of the visual system",
"pos": [],
"type": ""
},
"tail": {
"name": "BTX - B",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "parasympathetic dysfunction of the visual system",
"pos": [],
"type": ""
},
"tail": {
"name": "BTX - B",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
We consider asterixis to be an easily overlooked sign of neurotoxicity , which may occur even at low or moderate dosage levels , if certain drugs as lithium or clozapine are used in combination with CBZ .
|
[
{
"head": {
"name": "asterixis",
"pos": [],
"type": ""
},
"tail": {
"name": "CBZ",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "asterixis",
"pos": [],
"type": ""
},
"tail": {
"name": "clozapine",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "asterixis",
"pos": [],
"type": ""
},
"tail": {
"name": "lithium",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "neurotoxicity",
"pos": [],
"type": ""
},
"tail": {
"name": "CBZ",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "neurotoxicity",
"pos": [],
"type": ""
},
"tail": {
"name": "clozapine",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "neurotoxicity",
"pos": [],
"type": ""
},
"tail": {
"name": "lithium",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
OBJECTIVE : To describe the development of valproate - related reproductive endocrine disorders in women with epilepsy .
|
[
{
"head": {
"name": "reproductive endocrine disorders",
"pos": [],
"type": ""
},
"tail": {
"name": "valproate",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Alternating sinus rhythm and intermittent sinoatrial ( S - A ) block was observed in a 57-year - old woman , under treatment for angina with 80 mg propranolol daily .
|
[
{
"head": {
"name": "Alternating sinus rhythm",
"pos": [],
"type": ""
},
"tail": {
"name": "propranolol",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "intermittent sinoatrial ( S - A ) block",
"pos": [],
"type": ""
},
"tail": {
"name": "propranolol",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Since imiquimod induces large amounts of type I interferon production from TLR7-expressing plasmacytoid dendritic cell precursors ( PDCs ) , the natural interferon - producing cells of the peripheral blood , we asked whether PDCs are present in psoriatic skin .
|
[
{
"head": {
"name": "large amounts of type I interferon production",
"pos": [],
"type": ""
},
"tail": {
"name": "imiquimod",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
PURPOSE : To describe transient structured visual hallucinations in a patient with vascular age - related macular degeneration ( AMD ) , following an intravitreal Avastin - injection .
|
[
{
"head": {
"name": "transient structured visual hallucinations",
"pos": [],
"type": ""
},
"tail": {
"name": "Avastin",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Cyanamide - induced liver dysfunction after abstinence in alcoholics : a long - term follow - up study on four cases .
|
[
{
"head": {
"name": "liver dysfunction",
"pos": [],
"type": ""
},
"tail": {
"name": "Cyanamide",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Acute nitrite toxicity results from industrial exposure , accidental ingestion ( e.g. , abuse of organic nitrites as an aphrodisiac , especially in the male homosexual population ) , and suicidal ingestion .
|
[
{
"head": {
"name": "nitrite toxicity",
"pos": [],
"type": ""
},
"tail": {
"name": "nitrite",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
The authors report a longitudinal case study of a woman with a history of bipolar affective disorder in which L - dopa shortened the manic - depressive cycle length when administered in a double - blind trial .
|
[
{
"head": {
"name": "shortened the manic - depressive cycle",
"pos": [],
"type": ""
},
"tail": {
"name": "L - dopa",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
On the next day , after a total dose of only 600 mg of danazol , gingival bleeding and purpura occurred .
|
[
{
"head": {
"name": "gingival bleeding",
"pos": [],
"type": ""
},
"tail": {
"name": "danazol",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "purpura",
"pos": [],
"type": ""
},
"tail": {
"name": "danazol",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Erythema multiforme associated with phenytoin and cranial radiation therapy : a report of three patients and review of the literature .
|
[
{
"head": {
"name": "Erythema multiforme",
"pos": [],
"type": ""
},
"tail": {
"name": "phenytoin",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
It is well - recognized that flucloxacillin may occasionally result in fatal hepatic injury .
|
[
{
"head": {
"name": "fatal hepatic injury",
"pos": [],
"type": ""
},
"tail": {
"name": "flucloxacillin",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Clinical and morphological features of gold neuropathy .
|
[
{
"head": {
"name": "neuropathy",
"pos": [],
"type": ""
},
"tail": {
"name": "gold",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Various case reports concerning dapsone - induced agranulocytosis are reviewed .
|
[
{
"head": {
"name": "agranulocytosis",
"pos": [],
"type": ""
},
"tail": {
"name": "dapsone",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
This article describes two cases of aplastic anemia , at least one of which was almost certainly induced by the use of methazolamide , and one case of agranulocytosis related to the use of methazolamide .
|
[
{
"head": {
"name": "agranulocytosis",
"pos": [],
"type": ""
},
"tail": {
"name": "methazolamide",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "aplastic anemia",
"pos": [],
"type": ""
},
"tail": {
"name": "methazolamide",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
However , in 1993 , a clinical study involving 400 patients on the Thai - Burmese border revealed cardiac effects of antimalarial treatment with halofantrine , including one sudden death after the treatment .
|
[
{
"head": {
"name": "cardiac effects",
"pos": [],
"type": ""
},
"tail": {
"name": "halofantrine",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "sudden death",
"pos": [],
"type": ""
},
"tail": {
"name": "halofantrine",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Quetiapine - induced leucopenia and thrombocytopenia .
|
[
{
"head": {
"name": "leucopenia",
"pos": [],
"type": ""
},
"tail": {
"name": "Quetiapine",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "thrombocytopenia",
"pos": [],
"type": ""
},
"tail": {
"name": "Quetiapine",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
These findings mean that the effect of the MP pulse therapy on renal function depends on the clinical state of the patient and that renal deterioration after the pulse therapy may be more marked in patients who are more nephrotic and more impaired in renal function and suggest that increasing sodium and water retention during an MP therapy and the associated renal interstitial edema , proposed as one of the mechanisms of acute renal failure occurring in patients with minimal - change nephrotic syndrome , may be responsible for the MP - induced transient renal failure .
|
[
{
"head": {
"name": "transient renal failure",
"pos": [],
"type": ""
},
"tail": {
"name": "MP",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Metabolic acidosis induced by cetrimide - chlorhexidine solution in hydatid cyst surgery .
|
[
{
"head": {
"name": "Metabolic acidosis",
"pos": [],
"type": ""
},
"tail": {
"name": "cetrimide",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "Metabolic acidosis",
"pos": [],
"type": ""
},
"tail": {
"name": "chlorhexidine",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Anaphylactic reaction to recombinant insulin - like growth factor - I .
|
[
{
"head": {
"name": "Anaphylactic reaction",
"pos": [],
"type": ""
},
"tail": {
"name": "recombinant insulin - like growth factor - I",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Interstitial pneumonitis and alveolar hemorrhage complicating use of rituximab : case report and review of the literature .
|
[
{
"head": {
"name": "alveolar hemorrhage",
"pos": [],
"type": ""
},
"tail": {
"name": "rituximab",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "Interstitial pneumonitis",
"pos": [],
"type": ""
},
"tail": {
"name": "rituximab",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Clinicians should include phenolphthalein in their list of possible causes of drug - induced TEN .
|
[
{
"head": {
"name": "TEN",
"pos": [],
"type": ""
},
"tail": {
"name": "phenolphthalein",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Intravenous valproate associated with significant hypotension in the treatment of status epilepticus .
|
[
{
"head": {
"name": "hypotension",
"pos": [],
"type": ""
},
"tail": {
"name": "valproate",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Cardiac arrest associated with sulprostone use during caesarean section .
|
[
{
"head": {
"name": "Cardiac arrest",
"pos": [],
"type": ""
},
"tail": {
"name": "sulprostone",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Retinopathy in hepatitis C patients due to combination therapy with pegylated interferon and ribavirin .
|
[
{
"head": {
"name": "Retinopathy",
"pos": [],
"type": ""
},
"tail": {
"name": "pegylated interferon",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "Retinopathy",
"pos": [],
"type": ""
},
"tail": {
"name": "ribavirin",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Celiprolol pneumonitis .
|
[
{
"head": {
"name": "pneumonitis",
"pos": [],
"type": ""
},
"tail": {
"name": "Celiprolol",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
BACKGROUND : Hydroxyurea is a cytostatic agent used to treat myeloproliferative disorders and long - term treatment is associated with mucocutaneous adverse events and nail hyperpigmentation .
|
[
{
"head": {
"name": "mucocutaneous adverse events",
"pos": [],
"type": ""
},
"tail": {
"name": "Hydroxyurea",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "nail hyperpigmentation",
"pos": [],
"type": ""
},
"tail": {
"name": "Hydroxyurea",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
After 3- to 13-month period of therapy without indapamide , glucose levels of all patients decreased and diabetes disappeared .
|
[
{
"head": {
"name": "diabetes",
"pos": [],
"type": ""
},
"tail": {
"name": "indapamide",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
We present a case of cutaneous leucocytoclastic vasculitis in which amphotericin B might presumably be the aetiological factor .
|
[
{
"head": {
"name": "cutaneous leucocytoclastic vasculitis",
"pos": [],
"type": ""
},
"tail": {
"name": "amphotericin B",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
It should be emphasized that the recurrence of nephrotic syndrome was observed after the following chemotherapy , including M - CSF , whereas the bone marrow still remained completely remitted .
|
[
{
"head": {
"name": "nephrotic syndrome",
"pos": [],
"type": ""
},
"tail": {
"name": "M - CSF",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
DISCUSSION : The Naranjo probability scale indicated a probable relationship between sertraline treatment and the onset of rhabdomyolysis .
|
[
{
"head": {
"name": "rhabdomyolysis",
"pos": [],
"type": ""
},
"tail": {
"name": "sertraline",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
This report presents a case of acute lung injury developing within hours after administration of mefloquine for a low - level Plasmodium falciparum malaria , which was persistent despite halofantrine therapy .
|
[
{
"head": {
"name": "acute lung injury",
"pos": [],
"type": ""
},
"tail": {
"name": "mefloquine",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Hypoglycemia can be a serious side effect of etanercept in patients already on antidiabetic medications known to cause hypoglycemia , such as sulfonylureas , meglitinides , and insulin .
|
[
{
"head": {
"name": "Hypoglycemia",
"pos": [],
"type": ""
},
"tail": {
"name": "etanercept",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "hypoglycemia",
"pos": [],
"type": ""
},
"tail": {
"name": "etanercept",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "hypoglycemia",
"pos": [],
"type": ""
},
"tail": {
"name": "insulin",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "hypoglycemia",
"pos": [],
"type": ""
},
"tail": {
"name": "meglitinides",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "hypoglycemia",
"pos": [],
"type": ""
},
"tail": {
"name": "sulfonylureas",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Dexamethasone treatment of amiodarone - induced thyrotoxicosis ( AIT ) with or without persistent administration of the drug .
|
[
{
"head": {
"name": "thyrotoxicosis",
"pos": [],
"type": ""
},
"tail": {
"name": "amiodarone",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Acute bilateral phrenic neuropathy following treatment with adalimumab .
|
[
{
"head": {
"name": "Acute bilateral phrenic neuropathy",
"pos": [],
"type": ""
},
"tail": {
"name": "adalimumab",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
A unique case of a transient , nonpigmenting fixed drug eruption caused by the radiopaque contrast medium iothalamate is reported .
|
[
{
"head": {
"name": "fixed drug eruption",
"pos": [],
"type": ""
},
"tail": {
"name": "iothalamate",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Indolent aspergillus arthritis complicating fludarabine - based non - myeloablative stem cell transplantation .
|
[
{
"head": {
"name": "aspergillus arthritis",
"pos": [],
"type": ""
},
"tail": {
"name": "fludarabine",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Salicylate hepato toxicity in rheumatic fever .
|
[
{
"head": {
"name": "hepato toxicity",
"pos": [],
"type": ""
},
"tail": {
"name": "Salicylate",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Ethambutol toxicity manifesting as acute onset psychosis .
|
[
{
"head": {
"name": "acute onset psychosis",
"pos": [],
"type": ""
},
"tail": {
"name": "Ethambutol",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Dystonia associated with carbamazepine administration : experience in brain - damaged children .
|
[
{
"head": {
"name": "Dystonia",
"pos": [],
"type": ""
},
"tail": {
"name": "carbamazepine",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Fixed drug eruption in hands caused by omeprazole .
|
[
{
"head": {
"name": "eruption",
"pos": [],
"type": ""
},
"tail": {
"name": "omeprazole",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Discontinuation of the itraconazole caused resolution of the drug eruption .
|
[
{
"head": {
"name": "drug eruption",
"pos": [],
"type": ""
},
"tail": {
"name": "itraconazole",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
We report a patient with chronic renal failure and ischemic heart disease who developed clinically significant methemoglobinemia after an axillary block with bupivacaine and additional injection of lidocaine in the operative field .
|
[
{
"head": {
"name": "methemoglobinemia",
"pos": [],
"type": ""
},
"tail": {
"name": "bupivacaine",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "methemoglobinemia",
"pos": [],
"type": ""
},
"tail": {
"name": "lidocaine",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Olanzapine - induced hyperglycaemic coma and neuroleptic malignant syndrome : case report and review of literature .
|
[
{
"head": {
"name": "hyperglycaemic coma",
"pos": [],
"type": ""
},
"tail": {
"name": "Olanzapine",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "neuroleptic malignant syndrome",
"pos": [],
"type": ""
},
"tail": {
"name": "Olanzapine",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
We report a case of reversible DKA and new - onset DM that developed in a demented patient who was treated with quetiapine for 14 days .
|
[
{
"head": {
"name": "DKA",
"pos": [],
"type": ""
},
"tail": {
"name": "quetiapine",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "DM",
"pos": [],
"type": ""
},
"tail": {
"name": "quetiapine",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
We report a patient with pulmonary adenocarcinoma complicated by the syndrome of inappropriate secretion of antidiuretic hormone ( SIADH ) following systemic chemotherapy with cisplatin ( CDDP ) and vindesine ( VDS ) .
|
[
{
"head": {
"name": "SIADH",
"pos": [],
"type": ""
},
"tail": {
"name": "CDDP",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "SIADH",
"pos": [],
"type": ""
},
"tail": {
"name": "cisplatin",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "SIADH",
"pos": [],
"type": ""
},
"tail": {
"name": "VDS",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "SIADH",
"pos": [],
"type": ""
},
"tail": {
"name": "vindesine",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "syndrome of inappropriate secretion of antidiuretic hormone",
"pos": [],
"type": ""
},
"tail": {
"name": "CDDP",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "syndrome of inappropriate secretion of antidiuretic hormone",
"pos": [],
"type": ""
},
"tail": {
"name": "cisplatin",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "syndrome of inappropriate secretion of antidiuretic hormone",
"pos": [],
"type": ""
},
"tail": {
"name": "VDS",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "syndrome of inappropriate secretion of antidiuretic hormone",
"pos": [],
"type": ""
},
"tail": {
"name": "vindesine",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Sirolimus - eluting stent thrombosis several years after clopidogrel discontinuation .
|
[
{
"head": {
"name": "Sirolimus - eluting stent thrombosis",
"pos": [],
"type": ""
},
"tail": {
"name": "clopidogrel",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
The observation of cutaneous vasculitis during administration of propylthiouracil suggested that clinical awareness of this complication should be of considerable importance .
|
[
{
"head": {
"name": "cutaneous vasculitis",
"pos": [],
"type": ""
},
"tail": {
"name": "propylthiouracil",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Nephrotic range pseudoproteinuria in a tolmetin - treated patient .
|
[
{
"head": {
"name": "Nephrotic range pseudoproteinuria",
"pos": [],
"type": ""
},
"tail": {
"name": "tolmetin",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Chlorambucil - induced chromosome damage to human lymphocytes is dose - dependent and cumulative .
|
[
{
"head": {
"name": "chromosome damage",
"pos": [],
"type": ""
},
"tail": {
"name": "Chlorambucil",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Methylphenidate ( Ritalin ) - associated cataract and glaucoma .
|
[
{
"head": {
"name": "cataract",
"pos": [],
"type": ""
},
"tail": {
"name": "Methylphenidate",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "cataract",
"pos": [],
"type": ""
},
"tail": {
"name": "Ritalin",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "glaucoma",
"pos": [],
"type": ""
},
"tail": {
"name": "Methylphenidate",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "glaucoma",
"pos": [],
"type": ""
},
"tail": {
"name": "Ritalin",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
The visual loss in this patient seems to result from phenol neurotoxicity rather than mechanical compression of the intraorbital optic nerve .
|
[
{
"head": {
"name": "neurotoxicity",
"pos": [],
"type": ""
},
"tail": {
"name": "phenol",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "visual loss",
"pos": [],
"type": ""
},
"tail": {
"name": "phenol",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Acyclovir neurotoxicity : clinical experience and review of the literature .
|
[
{
"head": {
"name": "neurotoxicity",
"pos": [],
"type": ""
},
"tail": {
"name": "Acyclovir",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
This case highlights the need to monitor liver enzymes in patients treated with 6-TG and identifies the need for additional research focused on the mechanism of thiopurine - induced hepatic injury .
|
[
{
"head": {
"name": "hepatic injury",
"pos": [],
"type": ""
},
"tail": {
"name": "thiopurine",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Fatal pulmonary fibrosis following 1,3-bis(2-chloroethyl ) - 1-nitrosourea ( BCNU ) therapy .
|
[
{
"head": {
"name": "Fatal pulmonary fibrosis",
"pos": [],
"type": ""
},
"tail": {
"name": "1,3-bis(2-chloroethyl ) - 1-nitrosourea",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "Fatal pulmonary fibrosis",
"pos": [],
"type": ""
},
"tail": {
"name": "BCNU",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Nifedipine may induce , or aggravate , pre - existing , gastro - oesophageal reflux .
|
[
{
"head": {
"name": "gastro - oesophageal reflux",
"pos": [],
"type": ""
},
"tail": {
"name": "Nifedipine",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Chronic myelogenous leukemia ( CML ) , hepatitis C , and interferon alpha ( IFNalpha ) have all been associated with renal dysfunction .
|
[
{
"head": {
"name": "renal dysfunction",
"pos": [],
"type": ""
},
"tail": {
"name": "IFNalpha",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "renal dysfunction",
"pos": [],
"type": ""
},
"tail": {
"name": "interferon alpha",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
This was accepted as evidence for propranolol being the cause of this conduction disorder .
|
[
{
"head": {
"name": "conduction disorder",
"pos": [],
"type": ""
},
"tail": {
"name": "propranolol",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Eleven days after initiation of therapy with amiodarone , the patient experienced syncope and was noted to have recurrent episodes of polymorphous ventricular tachycardia .
|
[
{
"head": {
"name": "polymorphous ventricular tachycardia",
"pos": [],
"type": ""
},
"tail": {
"name": "amiodarone",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "syncope",
"pos": [],
"type": ""
},
"tail": {
"name": "amiodarone",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
In conclusion , RSDS is a relevant osteoarticular complication in patients receiving either anticalcineurinic drug ( CyA or tacrolimus ) , even under monotherapy or with a low steroid dose .
|
[
{
"head": {
"name": "RSDS",
"pos": [],
"type": ""
},
"tail": {
"name": "CyA",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "RSDS",
"pos": [],
"type": ""
},
"tail": {
"name": "tacrolimus",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Although fluoxetine - induced headache occurred in one patient , the other five reported no side effects at the doses used .
|
[
{
"head": {
"name": "headache",
"pos": [],
"type": ""
},
"tail": {
"name": "fluoxetine",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
In the present paper , we describe two patients with active UC who developed a severe systemic CMV infection during a treatment with an oral microemulsion form of cyclosporine .
|
[
{
"head": {
"name": "severe systemic CMV infection",
"pos": [],
"type": ""
},
"tail": {
"name": "cyclosporine",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Two patients who developed decreased visual acuity after several months of ethambutol treatment for Mycobacterium avium - intracellulare infection had bitemporal visual field defects that suggested optic chiasm damage .
|
[
{
"head": {
"name": "bitemporal visual field defects",
"pos": [],
"type": ""
},
"tail": {
"name": "ethambutol",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "decreased visual acuity",
"pos": [],
"type": ""
},
"tail": {
"name": "ethambutol",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Although gabapentin withdrawal has been previously reported and usually consists of anxiety , diaphoresis , and palpitations , this is the first reported patient with generalized seizures and status epilepticus secondary to gabapentin withdrawal .
|
[
{
"head": {
"name": "anxiety",
"pos": [],
"type": ""
},
"tail": {
"name": "gabapentin",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "diaphoresis",
"pos": [],
"type": ""
},
"tail": {
"name": "gabapentin",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "generalized seizures",
"pos": [],
"type": ""
},
"tail": {
"name": "gabapentin",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "generalized seizures",
"pos": [],
"type": ""
},
"tail": {
"name": "gabapentin",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "palpitations",
"pos": [],
"type": ""
},
"tail": {
"name": "gabapentin",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "status epilepticus",
"pos": [],
"type": ""
},
"tail": {
"name": "gabapentin",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "status epilepticus",
"pos": [],
"type": ""
},
"tail": {
"name": "gabapentin",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
We report four cases of encephalopathy coincident with elevated aluminum levels as well as one patient who developed seizures while receiving continuous bladder irrigations with alum .
|
[
{
"head": {
"name": "elevated aluminum levels",
"pos": [],
"type": ""
},
"tail": {
"name": "alum",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "encephalopathy",
"pos": [],
"type": ""
},
"tail": {
"name": "alum",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "seizures",
"pos": [],
"type": ""
},
"tail": {
"name": "alum",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
We report 3 children with epilepsy who developed facial motor tics after initiation of CBZ for complex partial seizures .
|
[
{
"head": {
"name": "facial motor tics",
"pos": [],
"type": ""
},
"tail": {
"name": "CBZ",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Colitis as a manifestation of infliximab - associated disseminated cryptococcosis .
|
[
{
"head": {
"name": "Colitis",
"pos": [],
"type": ""
},
"tail": {
"name": "infliximab",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "disseminated cryptococcosis",
"pos": [],
"type": ""
},
"tail": {
"name": "infliximab",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Based on the clinical status of the patient , it was suspected that several conditions contributed to the abnormal hypersensitivity to warfarin .
|
[
{
"head": {
"name": "abnormal hypersensitivity",
"pos": [],
"type": ""
},
"tail": {
"name": "warfarin",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Interstitial pneumopathy and low - dosage amiodarone .
|
[
{
"head": {
"name": "Interstitial pneumopathy",
"pos": [],
"type": ""
},
"tail": {
"name": "amiodarone",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
The patient was given methimazole instead of propylthiouracil but , 10 weeks later , agranulocytosis again occurred .
|
[
{
"head": {
"name": "agranulocytosis",
"pos": [],
"type": ""
},
"tail": {
"name": "methimazole",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
We presented the case of a patient who developed a cutaneous reaction induced by captopril with positive patch test .
|
[
{
"head": {
"name": "cutaneous reaction",
"pos": [],
"type": ""
},
"tail": {
"name": "captopril",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Hepatotoxicity of hycanthone in patients with metastatic breast cancer .
|
[
{
"head": {
"name": "Hepatotoxicity",
"pos": [],
"type": ""
},
"tail": {
"name": "hycanthone",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Myoclonus and seizures disappeared after discontinuation of L - dopa and the introduction of valproate sodium ( VPA ) .
|
[
{
"head": {
"name": "Myoclonus",
"pos": [],
"type": ""
},
"tail": {
"name": "L - dopa",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "seizures",
"pos": [],
"type": ""
},
"tail": {
"name": "L - dopa",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
METHODS : A 68-year - old man developed intense conjunctival hyperemia and cystoid macula edema after switching from latanoprost to bimatoprost 9 months after cataract surgery in an eye at low - risk for this cystoid macular edema .
|
[
{
"head": {
"name": "cystoid macula edema",
"pos": [],
"type": ""
},
"tail": {
"name": "bimatoprost",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "cystoid macula edema",
"pos": [],
"type": ""
},
"tail": {
"name": "latanoprost",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "cystoid macular edema",
"pos": [],
"type": ""
},
"tail": {
"name": "bimatoprost",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "cystoid macular edema",
"pos": [],
"type": ""
},
"tail": {
"name": "latanoprost",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "intense conjunctival hyperemia",
"pos": [],
"type": ""
},
"tail": {
"name": "bimatoprost",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "intense conjunctival hyperemia",
"pos": [],
"type": ""
},
"tail": {
"name": "latanoprost",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
We report a premature infant who developed seizures associated with intraventricular administration of nafcillin and discuss the need for electroencephalographic monitoring of patients receiving intraventricular antibiotics .
|
[
{
"head": {
"name": "seizures",
"pos": [],
"type": ""
},
"tail": {
"name": "nafcillin",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Severe loss of vision after removal of cataract caused by intravitreal triamcinolone in combination with photodynamic therapy for exudative age - related macular degeneration .
|
[
{
"head": {
"name": "cataract",
"pos": [],
"type": ""
},
"tail": {
"name": "triamcinolone",
"pos": [],
"type": ""
},
"type": "adverse effect"
},
{
"head": {
"name": "Severe loss of vision",
"pos": [],
"type": ""
},
"tail": {
"name": "triamcinolone",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Our objective is to present a retrospective analysis of the DWI findings in four patients who suffered subacute neurotoxicity after intrathecal MTX .
|
[
{
"head": {
"name": "subacute neurotoxicity",
"pos": [],
"type": ""
},
"tail": {
"name": "MTX",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
Intravenous diazepam exacerbated the seizures .
|
[
{
"head": {
"name": "seizures",
"pos": [],
"type": ""
},
"tail": {
"name": "diazepam",
"pos": [],
"type": ""
},
"type": "adverse effect"
}
] |
ADE_corpus
|
[
"adverse effect"
] |
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