manufernandezbur/tox_nontox_clustered_2025

485,648

Q68VX0

MNITFIGSGYVGLVSGIIMGYLGHNVTCFDNDDVKISKLNKKILPIYEAKLDEYLKQALESDRLKFTNIYSNDFRNVDAVFITVGTPSKELGEADLKYVYDAVDKVSKHINKDCLIVIKSTVPPGSCNNIIAYLKAKGFSFNVASNPEFLREGSAVEDFLYPDRIVVGVNNQESEALLRTIYAPLIEQGVKFLVTNLVTSELIKYASNSFLATKIAFINEMADLCEKIGANIKDLSQGVGLDQRIGRNFLNAGPGFGGSCFPKDILALNNLVENYKIDCKILKSVIKSNKLRPGNMVAKIATLLDGDLKGRNIAILGLTYKAGTDDVRASPAIEIITILLNKDVYVKAFDPIGLENAKKNLEHKNLLYFASAVEACESVDIIVIATEWSEFKELNWQEIYDLVKSPMIIDLRNILDNEVMKKIGFRYYAVGSKI

UDP-glucose 6-dehydrogenase (UDP-Glc dehydrogenase) (UDP-GlcDH) (UDPGDH) (EC 1.1.1.22)

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

434

48,146

NAD;Oxidoreductase

GO:0000271; GO:0003979; GO:0006065; GO:0051287

Inferred from homology

2

null

PF00984;PF03720;PF03721;

IPR008927;IPR036291;IPR017476;IPR014027;IPR036220;IPR014026;IPR001732;IPR028357;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

udg RT0766

false

Rickettsia typhi

100

row_466630

false

null

485,689

Q68W98

MGQNFSKKSSNDLVSRIIFTIFMLIICRIGSFIPIPGIDSIALNSVAEKNQFGILGMFNMLSGGSLGRMSIFALAIMPYITASIIIQLMSVAYKPLENLKKEGESGKRKINQLSRYLTVLLASFQAYGVALSLESMVTNTGPVVILAGFFFRVTTVITLVVGTMLLMWLGEQITQRGIGNGTSLIIFIGIISGVPSAIISMFELSRKGALSPLIAITVCIGVVLLIAIIIFFEKAQRKLLVQYPKRQVGNKIYGGEATHMPLKLNTSGVIPPIFASSILLFPTTLANFSNSNSETMSMLSYYLGHGKPVYILLYVVLIMFFSFFYTAIVFNSEETANNLRKYGAYIPGKRPGKNTSDYFDYILTRLTVIGGLYLSIICVIPELLMNKYVISLSLGGTSFLIVVNVVLDTMTQIQTYLFSSKYEGLMKKIKLKN

Protein translocase subunit SecY

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

433

47,681

Cell inner membrane;Cell membrane;Membrane;Protein transport;Translocation;Transmembrane;Transmembrane helix;Transport

GO:0005886; GO:0006605; GO:0043952; GO:0065002

Inferred from homology

2

SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-Rule:MF_01465}; Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01465}.

null

TRANSMEM 17..37; /note="Helical"; /evidence="ECO:0000255|HAMAP-Rule:MF_01465"; TRANSMEM 71..91; /note="Helical"; /evidence="ECO:0000255|HAMAP-Rule:MF_01465"; TRANSMEM 117..137; /note="Helical"; /evidence="ECO:0000255|HAMAP-Rule:MF_01465"; TRANSMEM 141..161; /note="Helical"; /evidence="ECO:0000255|HAMAP-Rule:MF_01465"; TRANSMEM 184..204; /note="Helical"; /evidence="ECO:0000255|HAMAP-Rule:MF_01465"; TRANSMEM 212..232; /note="Helical"; /evidence="ECO:0000255|HAMAP-Rule:MF_01465"; TRANSMEM 268..288; /note="Helical"; /evidence="ECO:0000255|HAMAP-Rule:MF_01465"; TRANSMEM 310..330; /note="Helical"; /evidence="ECO:0000255|HAMAP-Rule:MF_01465"; TRANSMEM 366..386; /note="Helical"; /evidence="ECO:0000255|HAMAP-Rule:MF_01465"; TRANSMEM 388..408; /note="Helical"; /evidence="ECO:0000255|HAMAP-Rule:MF_01465"

PF00344;

IPR026593;IPR002208;IPR030659;IPR023201;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

secY RT0631

false

Rickettsia typhi

101

row_466670

false

null

485,804

Q68XR8

MLYEKFEYNINNLVGNFGLSKIAIAVSGGSDSVALLYLANIWAEKNNIELFIISVDHNLRAQSKQENYYIQSISNNLKRKYYNLSFDHQNNFSNLQARAREGRYDLMTNLCLELDVLVLLTAHHEDDYVENFCLRLERNSGIFGLSSSNIHWYNNIQIIRPLYNIPKSELVKYLVTNKIKWFEDESNLSDKYRRNIIRQKLFKEENYIKAEISVQQLKTNKLIEDELKPELISAIGEAVKIFEYGFTFLDLVKFDKFSNEVKVQIINFLLIMISGQSRSARFYSIAPILKLISQNVNFKKTVHGCVITRIQNELLIYREFGKKLPKSKILLDKSVIWDNRFCITKNQETPDCVITYLSLEDYKVIKKQLDLKHLKNLSCKNHNAILFTLPIIKILEKVIAIPHISYYDNDMWNFEVSFAPNFVSRFTHFC

tRNA(Ile)-lysidine synthase (EC 6.3.4.19) (tRNA(Ile)-2-lysyl-cytidine synthase) (tRNA(Ile)-lysidine synthetase)

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

430

50,397

ATP-binding;Cytoplasm;Ligase;Nucleotide-binding;tRNA processing

GO:0005524; GO:0005737; GO:0006400; GO:0032267

Inferred from homology

2

SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01161}.

null

PF01171;

IPR014729;IPR011063;IPR012094;IPR012795;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

tilS RT0088

false

Rickettsia typhi

102

row_466785

false

null

485,742

Q68WZ3

MLLSKYFLPILKEEPSEAQVISHKLMLRSGMIMKQASGLYTWLPLGLKVLKNIENIVRSNMNKVGALEVLMPCIQPAHLWIESGRFEYYGKEMLKFQDRHDNTLLFGPTNEDMITDIFRRNIKSYKDLPKNLYHIQWKFRDEIRPRFGVMRGREFLMKDAYSFDINQENAVNTYNKMYKAYINTFRDLGVFAIPVIADNGPIGGNLSHEFHIIAETGESTIYYDKRFKILKDNPDIDVEEIKSWYAAAEEKHDVNKLSSFPEGITSSKGIEVGHIFYIGSKYSVNMNALINDEYGKLIPVEMSSYGIGISRLAAAIIEANCDKKGIIWPFSVAPFKVSLINLNIHDNKCVELAAKTDKELSNKNIEVLYDDTEARPGSKFATHDLIGSPYQVIIGPKKAANNIVELKDRKTGVLEDIEIENLINYIRI

Proline--tRNA ligase (EC 6.1.1.15) (Prolyl-tRNA synthetase) (ProRS)

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

428

48,920

Aminoacyl-tRNA synthetase;ATP-binding;Cytoplasm;Ligase;Nucleotide-binding;Protein biosynthesis

GO:0004827; GO:0005524; GO:0005829; GO:0006433

Inferred from homology

2

SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01570}.

null

PF03129;PF00587;

IPR002314;IPR006195;IPR045864;IPR004154;IPR036621;IPR002316;IPR004500;IPR050062;IPR023716;IPR044140;IPR033730;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

proS RT0372

false

Rickettsia typhi

103

row_466723

false

null

266,756

Q68VW6

MLNIKWIRENQELFDEKLSQRFIEPMSSKIAMLDREKRKITSLIQEFQHARKVKSKILGNMVSKSGEEFEELQRDVNHINEKLEELEQTLDNNNELNELLNMLPNIPDEEVPYGIDESMNKLVRSYGNTNKNALNKQHFELGTKLNLMDFEQTAKISGSRFVTLKGDLAKLERALINFMVDIHTKEFDFFEISPPLLVRDSAMYNAGQLPKFSEESFITTNGYRLIPTAEVSLVNIVADTIIQREKLPMRYVAYTTCFRSEAGSSGRDTRGMIRLHQFGKVELVSITTPEESKNEHEYITNASETILKKLDLPYRVMLLCTGDMGFAAKKTYDIEVWLPGQNQYREIASCSNCGDFQARRMKARYKEFGSNETTLVHTLNASGLPIGRTIVAILENYQNNDGSITIPDVLINYMGGLKKITTYSE

Serine--tRNA ligase (EC 6.1.1.11) (Seryl-tRNA synthetase) (SerRS) (Seryl-tRNA(Ser/Sec) synthetase)

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

425

48,674

Aminoacyl-tRNA synthetase;ATP-binding;Cytoplasm;Ligase;Nucleotide-binding;Protein biosynthesis

GO:0004828; GO:0005524; GO:0005737; GO:0006434; GO:0016260

Inferred from homology

3

SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00176}.

null

PF02403;PF00587;

IPR002314;IPR006195;IPR045864;IPR002317;IPR015866;IPR042103;IPR033729;IPR010978;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

serS RT0770

false

Rickettsia typhi

104

row_251510

false

null

266,773

Q68W45

MVVDADKKELICSFCSKKQHEVKKLIAGPAVFICDECIDLCTDIMKEESKVALKQITASIPTPQKICKILNDYVVGQDKAKKILAVAVYNHYKRLEYVQSGNNDVELNKSNILLIGPTGSGKTLLAQTLAKILDVPFTMADATSLTEAGYVGEDVENILLRLLISAEFNIAKAQKGIIYIDEVDKIARKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQDFVQLDTSNILFICGGAFMGIDRIIRSRTNHSSIGFAANINIDKEKNNNEVLKSLEIEDLTKFGLIPEFIGRLPIVTTLEELDKESLITILTKPKNAIVKQYQKQFELDDAELVIEYSALEAIAEKALVKKTGARGLRSILEHLLLDSMYKVAELKKQRVTLTKEVVDGLIEPVMTSIISTKLNKKQQMIEDIPA

ATP-dependent Clp protease ATP-binding subunit ClpX

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

425

47,010

ATP-binding;Chaperone;Metal-binding;Nucleotide-binding;Zinc

GO:0005524; GO:0008270; GO:0009376; GO:0016887; GO:0046983; GO:0051082; GO:0051301; GO:0051603; GO:0140662

Inferred from homology

3

null

PF07724;PF10431;PF06689;

IPR003593;IPR050052;IPR003959;IPR019489;IPR004487;IPR046425;IPR027417;IPR010603;IPR038366;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

clpX RT0687

false

Rickettsia typhi

105

row_251527

false

null

485,660

Q68W48

MPGLLLLTTTMLLILFALIICFYIKTKTFKMQLQFLSEQNLEINNNNQLLNQEKITYLQKIEQLKCKLEYQERMIKDSEKIREESFASAKAALFDLGKDLSKQLIEIHKMENNTTRELAEKNIETASQKFNTELERLITMVGALNKDIEQSKGTVDLIKQSLLSPIGAGLLSEITLENILKSSGLRPNLDFIMQYSLTTSDSVKLRPDAIIFLPSGNLMVIDSKASKFLVDSQDNSVHLSKTMNYHLKTLTNKDYAENILTNLNKKTQNFNNVITLMFLPTEQAVEKVIAANPEFLQKAWGCNIFPVGPAGLMNMLSFAKFQITDNRRSENYKVIIEEVRKLLSSIGTIADYSKKIGYNLQNMVTNYDKFAASFNRNVMSRVKSIQKLGIDSGNKIIPATLERYQIVSAKSEIIEVDVENQHK

DNA recombination protein RmuC homolog

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

423

48,059

Coiled coil;DNA recombination

GO:0006310

Inferred from homology

2

null

PF02646;

IPR003798;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

rmuC RT0684

false

Rickettsia typhi

106

row_466641

false

null

266,867

Q68XY3

MLKEEDKIFINLYGQQSYDLKSSKKRGDWYNTKALLDKGRDFIIDEVKKSGLRGRGGAGFSTGMKWSFMPKNSEKPCYLVVNADESEPGTCKDRDILRFEPHKLIEGCLIASFAIGANNCYIYIRGEFYNEASNMQRALDEAYTEGLIGKNACGSGFDCNIYLHRGAGAYICGEETALLESLEGKKGMPRLKPPFPAGFGLYGCPTTINNVESIAVVPTILRRGASWFAAIGKPNNTGTKIFCISGHVNKPCNIEEAMGIPLKELIEKYAGGVRGGWDNLKAIIPGGASVPLLPKSLCEVEMDFDSLRTVGSGLGTGGIIVMDRSTDIIYAIARLSKFYMHESCGQCTPCREGTGWMWRVMMRLVNGNAKKTEIETLLNVTKEIEGHTICALGDAAAWPIQGLIRHFRDEIEERIKNFGIA

NADH-quinone oxidoreductase subunit F (EC 7.1.1.-) (NADH dehydrogenase I subunit F) (NDH-1 subunit F)

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

421

46,347

4Fe-4S;Flavoprotein;FMN;Iron;Iron-sulfur;Metal-binding;NAD;Quinone;Translocase

GO:0008137; GO:0010181; GO:0046872; GO:0048038; GO:0051287; GO:0051539

Inferred from homology

3

null

PF01512;PF10589;PF22461;

IPR050837;IPR001949;IPR011537;IPR011538;IPR037225;IPR019575;IPR037207;IPR054765;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

nuoF RT0021

false

Rickettsia typhi

107

row_251619

false

null

266,765

Q68W07

MNILNNNLYGMDKEIYEIIKNEKLRQNNVIELIASENFVSSAVLEAQGSILTNKYAEGYPSKRFYNGCDEVDKAEVLAIERAKKLFNCKYANVQPHSGSQANQAVYLALLQPCDTILGMSLDSGGHLTHGAAPNISGKWFNTVAYNVDKETYLIDYDEIKRLAVLHNPKLLIAGFSAYPRKIDFARFREIADKVGAYLMADIAHIAGLVATGEHQSPIPYAHVVTSTTHKTLRGPRGGLILSDYEEIGKKINSALFPGLQGGPLMHVIAAKAVAFLENLQPEYKCYIKQVISNAKALAISLQERGYDILTGGTDNHIVLVDLRKDGITGKCAANSLDRAGITCNKNAIPFDTTSPFVTSGIRFGTSACTTKGFKEKDFVLIGHMVAEILDGLKNNEDNSKTEQKVLSEVKKLIKLFPFYD

Serine hydroxymethyltransferase (SHMT) (Serine methylase) (EC 2.1.2.1)

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

420

46,198

Amino-acid biosynthesis;Cytoplasm;One-carbon metabolism;Pyridoxal phosphate;Transferase

GO:0004372; GO:0005829; GO:0019264; GO:0030170; GO:0035999

Inferred from homology

3

SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00051}.

null

PF00464;

IPR015424;IPR015421;IPR015422;IPR001085;IPR049943;IPR019798;IPR039429;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

glyA RT0728

false

Rickettsia typhi

108

row_251519

false

null

485,647

Q68VW8

MYKKLYLIGILLLGLISGLTFNLIFFTVPYQLSEAKYTTDIVGSISLAAFPYCLKVIWSPFIDKYSIPFLGVKFGHRRGWALVSQIFLILTMMWFLKRSPCNNLCITAIILFIIAFCSSTQDIVLDAYRIERTTSKKELSIAFTFSSIGFRLGMLLGSVGALYSSIIFGWNTVYKFALFITMVGPIVILCIKEPELKTKRNTTNNLIDLQQYFEVIKKSIISFKNEQKYLLLIILFVFLYKAADSIPMAMSIPLFLDLSFTTHEIAVIYKAYGLLIMIVGGTLGGILAAKIGIFHSVLIGGVIQLLSPIMFMILATIGYDIKTFIITITIQNFCSGFAGTIISIYFASLCNSEFVATQYSISSSFSSLSRIILASLGGICAKHLTWPVFFLCNTLFSMLFIPIFYIYRKKLHFINYSKKI

Putative transporter AmpG 3

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

420

47,304

Cell inner membrane;Cell membrane;Membrane;Transmembrane;Transmembrane helix;Transport

GO:0005886; GO:0022857

Inferred from homology

2

SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.

null

TRANSMEM 6..26; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 41..61; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 79..99; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 104..124; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 141..161; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 166..186; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 230..250; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 274..294; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 297..317; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 324..344; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 359..381; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 386..406; /note="Helical"; /evidence="ECO:0000255"

PF07690;

IPR004752;IPR011701;IPR020846;IPR036259;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

ampG3 RT0768

false

Rickettsia typhi

109

row_466629

false

null

266,786

Q68WF7

MQKLIIHGGKPLEGSINISGAKNAVLPIMAASILTNKLHITNVPKLTDVSTMKDLLQNHGACIRIIEHTDALEIIINTTNINKFTADYEIVRKMRASIWVLGPLLTKYGKAKVSLPGGCAIGARQVDLHIAVLKSMGAEIEIEDGYINASSKGRLKGTHFVFDKVSVGATINAILAAVLANGETVLFNCGREPEIVDLCYCLIKMGADILGVGSSTITIKGKDCLNETSYKVLSDRIEAGTYMFAAAITKGDVKICGIDYNIIENIALKLIETGIKVVQINNGVQVTYAGMLNSVDLETNPYPGFATDLQAQFMSLMSLSRGVSMITENIFENRFMHVPELCRMGADIVVRGNKAVVRGVEMLKGAEVMASDLRASVSLILAGLSTNSKTVLHRIYHLDRGFQDLEKKLSNCGADIKRV

UDP-N-acetylglucosamine 1-carboxyvinyltransferase (EC 2.5.1.7) (Enoylpyruvate transferase) (UDP-N-acetylglucosamine enolpyruvyl transferase) (EPT)

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

419

45,340

Cell cycle;Cell division;Cell shape;Cell wall biogenesis/degradation;Cytoplasm;Peptidoglycan synthesis;Pyruvate;Transferase

GO:0005737; GO:0008360; GO:0008760; GO:0009252; GO:0019277; GO:0051301; GO:0071555

Inferred from homology

3

SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00111}.

null

PF00275;

IPR001986;IPR036968;IPR050068;IPR013792;IPR005750;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

murA RT0568

false

Rickettsia typhi

110

row_251539

false

null

266,744

Q68VS3

MSYYDTIFNKHIDKIKSEGRYREFKSLKRQADNFPFAEYEDKQIVMWCINDYLGMSKHIKVMQASIDALLEYGVGSGGTRNIGGNNISILELEKELADLHSKETALVFTSGFVANDTTLASLAKIIPDIVFFSDELNHASIIAGITSSRAEKYVYRHLDVQHLEKLLQSVDINKPKIIVFESAYSMDGFFSPIKDIINLAKKYNALTFIDEVHTVGLYGKQGGGISELLDCSNQIDIIQGTLAKAYGTIGGYITSNYNLIDAIRLTAPGFIFTTSLPPVISTAATHSIRHLKVSNEERIKHQEVVTKLKNSFEHFNIPYLKNESHIIPIIIGDPIKATKVSNMLLNEYGIYVQHINFPTVPRGTERLRIIPTPAHTDKMINDLSTALVHIFAELDIELSSTKELNKEVRLHLIA

5-aminolevulinate synthase (EC 2.3.1.37) (5-aminolevulinic acid synthase) (Delta-ALA synthase) (Delta-aminolevulinate synthase)

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

414

46,460

Acyltransferase;Heme biosynthesis;Pyridoxal phosphate;Transferase

GO:0003870; GO:0006782; GO:0030170

Inferred from homology

3

null

PF00155;

IPR010961;IPR001917;IPR004839;IPR050087;IPR015424;IPR015421;IPR015422;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

hemA RT0829

false

Rickettsia typhi

111

row_251498

false

null

485,755

Q68X64

MIDNLQPLRGMKDLLPDDYQVHNYIINKARDVGVLYGYKQMSTPILEYTRVFNRCMGDSSDVISKEIYSFVDKSNNAIALRPEFTSGIIRSFISNGLHHKLPLKLFSTGPVFRYDRPQAGRQRQFHQLNYEYLGAKGAITDAETLKLAVDILKALEIEEDTTLELNSLGCSESRIVYQQKLVEYLNDFKDKLSGESKIRLNKNPMRILDSKSEIDQKIIANAPILSDYHTNESKKYFDELLKYLDILGIKYSINPRLVRGLDYYCHTVFEFTTQKLGSQATILAGGRYDMLSRIMGNYDVHAIGFAAGIERIALMKKYNIFVIKPVFVLPIGKNNICYALDIVDKLRLHNIISIIDPIGKIAKRIQRVLNEDAKFIIFVGDEEKMNNNLKFKDLKNQKEYIIDLEKVLELLK

Histidine--tRNA ligase (EC 6.1.1.21) (Histidyl-tRNA synthetase) (HisRS)

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

412

47,370

Aminoacyl-tRNA synthetase;ATP-binding;Cytoplasm;Ligase;Nucleotide-binding;Protein biosynthesis

GO:0004821; GO:0005524; GO:0005737; GO:0006427

Inferred from homology

2

SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00127}.

null

PF03129;PF13393;

IPR006195;IPR045864;IPR004154;IPR036621;IPR015807;IPR041715;IPR004516;IPR033656;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

hisS RT0298

false

Rickettsia typhi

112

row_466736

false

null

485,770

Q68XF0

MKENFNISKLKNGLTILTYNMPYVHSVAINLIAKVGARYENEEEEGISHFLEHMAFKGTKTRTAQQIAEEFDSIGGYFNAYTGYENTVYYVRVLSENCHKALNILADIIQNSIFADEEISKEYQIIMQEIAHHHDNPDDLIYETFYNTVYKDQPLGKSILGTAKTLVKFTQEHFLNFIGKHYNAENLYLSIAGNIEHNKIVIIAEELFASLKQGVTSSFIPAKYIGGKGFIHKELEQTSLVLGFECTSYINLEKLYQTYLLSIIFGGGVSSRLFQSIREKLGLAYVVGSYNSAYFDSGVFTIYASTAHEKLELLYSEIKNEIIKITETVSTEELMRAKIQLRSNLQMAQEQNSYKSEEIGKNYSVFGKYILPEEIIEIITNIKADDIINTANKIFSGTTALAIIGPNDLNGF

Uncharacterized zinc protease RT0210 (EC 3.4.24.-)

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

412

46,619

Hydrolase;Metal-binding;Metalloprotease;Protease;Zinc

GO:0004222; GO:0006508; GO:0046872

Inferred from homology

2

null

PF00675;PF05193;

IPR011249;IPR050361;IPR011765;IPR001431;IPR007863;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

RT0210

false

Rickettsia typhi

113

row_466751

false

null

266,788

Q68WH9

MTFIEEFIYKGYLHQCTDLDQLTAITQEVKIAAYIGFDCTATSLHIGSLMQIMILRLLQKHGHTPIVIIGGGTSKIGDPSGKEVTRKALTQEDIKRNTAGIKKSLSKFIKFGKDQGDAIILDNAEWLDSLNYLDFLRDFGRHFSVNRMLTMDSVKLRLERSHHLSFLELNYMLLQAYDFYYLSKHYNCILQLGGSDQWGNIVIGADLIRRISGKEVFGMTTPLLTTASGAKMGKTAAGAVWLNEDLLSPYDYYQYWRNCEDADVIRFAKLYSELDIIELNKFEHLVSEDINAAKKQLAYELTKLCHGERLAKLALETAVRIFEQGDIDENLHTFILAPEILQAGISAYKLFYNVNLARSKSEARKIIRGKGAKINDQLVEDENMTIDTNFLLDKKVIKLSVGKKRHILVKV

Tyrosine--tRNA ligase (EC 6.1.1.1) (Tyrosyl-tRNA synthetase) (TyrRS)

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

411

46,659

Aminoacyl-tRNA synthetase;ATP-binding;Cytoplasm;Ligase;Nucleotide-binding;Protein biosynthesis;RNA-binding

GO:0003723; GO:0004831; GO:0005524; GO:0005829; GO:0006437

Inferred from homology

3

SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_02006}.

null

PF00579;

IPR002305;IPR014729;IPR036986;IPR002307;IPR024088;IPR024107;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

tyrS RT0544

false

Rickettsia typhi

114

row_251541

false

null

266,799

Q68WP6

MNQQLKNLTLPIYMDYQSTTPIDPRVMEAMLPYFTTKFGNPHSRSHSFGWEAENAVENARSMIAKLIGADSKEIIFTSGATESNNLVIKGIAKFYGNKKNHIITLVSEHKCVLNACRYLEQEGIKITYLPIKPNGIIDLEILKNAITDQTLLVSVMAVNNEIGVIQPLREIGKICRERSVFFHSDIAQGFGKIPINVNEYNIDLASISGHKIYGPKGIGALYIRKKPRVRVTPLINGGGQERGMRSGTLPTPLIVGFGIAAEISYNEMEKDAQHVNYLFDRFLNNIYSRIPEVYLNGDKDQRYKGNLNLSFAGVEGESIILAIKDLAVSSGSACTSASLEPSYVLRSIGISEELAHTSIRFGIGRFTTEQEIDYAVNLICSKIDKLRKLSPLWEMMQEGIDLKKIKWTAH

Cysteine desulfurase IscS (EC 2.8.1.7)

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

410

45,761

2Fe-2S;Cytoplasm;Iron;Iron-sulfur;Metal-binding;Pyridoxal phosphate;Transferase

GO:0030170; GO:0031071; GO:0044571; GO:0046872; GO:0051537; GO:1990221

Inferred from homology

3

SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00331}.

null

PF00266;

IPR000192;IPR020578;IPR010240;IPR016454;IPR015424;IPR015421;IPR015422;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

iscS RT0473

false

Rickettsia typhi

115

row_251552

false

null

485,702

Q68WD6

MKIIVKIPVWMLLSLFILSPTTETIYTSGLPSLTKYFSIDGCITQITSTLYFLGFAVGILSLGRLSDIYGRRPIVLLGLFIYIVSSIISIFSVNIEMLMIARFIQAFGVSVGSVIGQSMARDSYQGAELSYVYAILSPWLLFIPSLGSYIGGYIIEYSSWHYVFVFFSLIGTILLALYYKILPETNYYIDFSQSSKYFEVFNIIIKDKILWLYAFIIGAFNGIYYGFFIEAPFILIDKMKVLPSFYGKLAFLLSFSAIFGGFLGGYLIKKRQVHDKKVMSIGFIFSLCGCILFVVNAFILEFILVSNGLAISMIFVPMMIHIIGHSLLIPITLRYALEDYAKVTGTAGSIFGAIYYIVIAAVTYCVSKIHGETISNFSLLCLVSSISSVISFYYICILYKKKSIVANEK

Uncharacterized transporter RT0591

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

409

45,873

Cell inner membrane;Cell membrane;Membrane;Transmembrane;Transmembrane helix;Transport

GO:0005886; GO:0042910; GO:1990961

Inferred from homology

2

SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.

null

TRANSMEM 3..23; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 43..63; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 73..93; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 95..115; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 135..155; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 162..182; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 209..229; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 248..268; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 283..303; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 309..329; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 346..366; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 379..399; /note="Helical"; /evidence="ECO:0000255"

PF07690;

IPR004812;IPR011701;IPR020846;IPR036259;IPR005829;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

RT0591

false

Rickettsia typhi

116

row_466683

false

null

485,666

Q68W71

MNFKCVQFQSIFNILFILIISFPGGLIYLLTGSTLSFWLRESEFDKITIGLFGLVNFIYILKFLWGPLLEKISFSTLSNRGYKYCLVITLINCIVCVYVLTSFNPNTNFTPFVLCLIVLAFFSSIYDMLIQSSQMLLITDKNWGISEAACTTGFRIGILISGSGALYLSTIISWQDVYRTMAILCIPSLLLIIFYPLKFKDKMIANDFDKFFSAFYDFIKKPKWIVIISFMLLYRLQDSFLSIMPNMFYLDIGYTKQDLAIGYKAFGMCAAIFGGVIGGFLCRKYEYSYLLKRVLIYHALSSLSFIYLYFLNQDIISLYIAVFCQEFTKGLTMSPFFSYQLKCCSSRYCITQIALITSITNVGTILIGSISGYAATYLGWSYFFIVAGLCFIPAYILILYLPKTINSV

Putative transporter AmpG 2

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

408

46,567

Cell inner membrane;Cell membrane;Membrane;Transmembrane;Transmembrane helix;Transport

GO:0005886; GO:0022857

Inferred from homology

2

SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.

null

TRANSMEM 11..31; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 49..69; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 84..104; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 110..130; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 154..174; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 177..197; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 224..244; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 261..281; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 294..311; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 315..337; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 353..373; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 382..402; /note="Helical"; /evidence="ECO:0000255"

PF07690;

IPR004752;IPR011701;IPR036259;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

ampG2 RT0660

false

Rickettsia typhi

117

row_466647

false

null

555,559

Q68X15

MQYLILSLIFLIPSLGMLTGLSIAATVLFFLLIIVITELISFIRKQEFSKKFLIKLYPRFGFDDIFCVKNRIKTELLFIAWCFISCLFTIHPINSLVTFTKVFALLFLRFVNNVVTFQNILYLKNSLILGIITAILLFFIEYSSHGFLTRMFKTHFGLYMLDRGCALLSITTWVVIIILFSNGKNINAFILYIVVLYLLSISDSLASFVGFSIGGIIFILARLIKKIFFKLITISLITGSLLFPIIAKQIDPHNLSEKYLATKPSAAHRLFIWHFVANKIIIKPILGYGFASSKYIKTSDNEMIDYRGEKLHPLPLHPHNNILQITLELGILGLALFLCLVYKYLKEIDNIKISNFRAASYSCFINYYIIGMISYNIWQTWWILSGIWILVLMKLLVKPDIIIDN

Putative polysaccharide ligase RT0347

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

405

46,583

Membrane;Transmembrane;Transmembrane helix

GO:0016020

Inferred from homology

1

SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.

null

TRANSMEM 23..43; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 77..97; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 120..140; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 156..178; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 201..221; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 227..247; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 270..290; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 322..342; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 353..375; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 377..397; /note="Helical"; /evidence="ECO:0000255"

PF04932;

IPR007016;IPR051533;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

RT0347

false

Rickettsia typhi

118

row_535570

false

null

266,792

Q68WK6

MPIKILMPALSPTMKDGNLARWLKKEGDKVNPGEVIAEIETDKATMEVESVDEGILAKIIIPQNSQNVPVNSLIAVLSEEGESTADIDAFIAKNNSVSLSLKTDTTLKKANESITNVEVVKHDLSKIFASPLAKRLAKIRNIRLESVQGSGPHGRIVKQDILSYSPSTAYNRDTEEYRSVPNNNIRQIIAKRLLESKQTVPHFYLSIECNVDKLLDIREDINKSFSEDKLTKISVNDFIILAVAKALQEVPNANASWAEDAIRYYNNVDISVAVAIENGIVTPIIKDANKKNIIELSHEMKILIKKAKDNKLTPVEFQGGGFTISNLGMYGIKNFNAIINTPQSCIMGVGASTKRAIVKNDQIIIATIMDVTLSADHRVIDGAVSAEFLASFKRFIEHPVLMLI

Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex (EC 2.3.1.12) (Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex) (E2)

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

404

44,546

Acyltransferase;Lipoyl;Transferase

GO:0004742; GO:0006086; GO:0045254

Inferred from homology

3

null

PF00198;PF00364;PF02817;

IPR003016;IPR001078;IPR000089;IPR023213;IPR045257;IPR036625;IPR006257;IPR004167;IPR011053;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

pdhC RT0517

false

Rickettsia typhi

119

row_251545

false

null

266,865

Q68XW3

MSLCTLEINLSAIKNNYRLLQDICTTALVGAAVKANGYGIGAMQIAKALIEENCQYFFVATSEEGINLRKALNNDITILVLNGVFTHDALELIQYNLTPVLNNLKQIEIWQKFSNLKEKILPCYLHFNTGLNRFGLNYDEIEQLINDRDLLKGLDLQYIISHLAASEEMDNPYNLAQLNRFKDYLEYFPNVKASLANSGGIFLGQDYHFDLARPGAALYGLNSLIEVSYNLSYKEKFERNTPALATTVCINKCADVNTRLTYKVPLKGSYRLQNPVTLKAPIIHLQNLTLDSHIGYNMTFTTKRDSIIATLPLGYADGFSRNFSNQGEVFINSRSVPIVGRVSMDLINIDVTDLPPSEVFLGQEVEIIGNYCTPDKIASIIGTVGYEVLTSLGSRYKRKYIS

Alanine racemase (EC 5.1.1.1)

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

402

45,046

Isomerase;Pyridoxal phosphate

GO:0005829; GO:0008784; GO:0030170; GO:0030632

Inferred from homology

3

null

PF00842;PF01168;

IPR000821;IPR009006;IPR011079;IPR001608;IPR020622;IPR029066;IPR005728;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

alr RT0042

false

Rickettsia typhi

120

row_251617

false

null

266,864

Q68XV9

MSIISTRLNSIKPSPTLAVVKKTLELKKAGVNIIALGAGEPDFDTPDNIKEVAITSIKDGFTKYTNVDGIPLLKQAIKNKFKRENNIDYELDEIIVSTGGKQVIYNLFMASLDKGDEVIIPVPYWVSYPDMVALSTGTPIFVNCGIENNFKLTVEALERSITDKTKWLIINSPSNPTGAGYNCKELENIAKTLRKYPNVNIMSDDIYEHITFDDFKFYTLAQIAPDLKERIFTVNGVSKAYSMTGWRIGYGAGSKALIKAMTVIQSQSTSNPCSISQMAAIEALNGTQDYIKPNALNFQKKRDLALSILEKVIYFECYKPEGAFYLFVKCDKIFGTKTKSGKIIANSNHFSEYLLEEAKVAVVPGVAFGLDGYFRISYATSMQELKEACIRIKQACNTL

Probable aspartate/prephenate aminotransferase (AspAT / PAT) (EC 2.6.1.1) (EC 2.6.1.79) (Transaminase A)

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

399

44,337

Aminotransferase;Cytoplasm;Pyridoxal phosphate;Transferase

GO:0004069; GO:0005737; GO:0006520; GO:0009058; GO:0030170; GO:0033854

Inferred from homology

3

SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q02635}.

null

PF00155;

IPR004839;IPR050596;IPR004838;IPR015424;IPR015421;IPR015422;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

aatA RT0046

false

Rickettsia typhi

121

row_251616

false

null

266,827

Q68X99

MNKEMTHKKSNGIIEWIDYRLPIFSFFKHFSYYQTPKNLNYLWTLGSIAGIALVIQIITGVILAMHYTPHVDHAFESVERIMRNVNYGWLLRYTHTVGASMFFATIYLHIARGLYYGSYKTPRELLWHIGIIIFLIMMATAFMGYVLPWGQMSYWSATVITNLFSAIPLIGEPIVIWLCGGFSVDNPTLNRFFSLHYLFPFIIVALVILHLLALHQHGSNNPKGIDVKSTKDTIPFHPYYTVKDFVGFGVYFIIFAYFIFYEPNYLGHPDNYIPANPLVTPAHIVPEWYFRPFYAILRAVPSKLAGVFLMFGSIFVLFLLPWLDTSKIRSGNYRPIYRIAFWIFMADCLFLGYLGSKPPAEPYIIISRFSACYYFCHFLVVLPLIGKYEKPLPLPNEL

Cytochrome b

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

398

46,114

Cell membrane;Electron transport;Heme;Iron;Membrane;Metal-binding;Respiratory chain;Transmembrane;Transmembrane helix;Transport

GO:0005886; GO:0008121; GO:0022904; GO:0045275; GO:0046872

Inferred from homology

3

SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.

null

TRANSMEM 45..65; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 97..117; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 129..149; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 164..184; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 192..212; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 245..265; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 304..324; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 335..355; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 364..384; /note="Helical"; /evidence="ECO:0000255"

PF00032;PF00033;

IPR005798;IPR036150;IPR005797;IPR027387;IPR030689;IPR048260;IPR048259;IPR016174;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

petB cytB RT0262

false

Rickettsia typhi

122

row_251580

false

null

266,840

Q68XI8

MSIKIIIPSLGESVTEATIAKWYKKLGDAVKTDELLLEIETDKVTLEVNAPCNGTIGKISKTDGANVTVGEEVGEINEIADTDTAWINNKKQEVSQHTSEQLVDKPAMASNILAPSVQKLVTENKLDPNNIKGTGRGGRITKYDVLETINTTPITIETHAINKTNEERTQRVRMSRLRKTIAQRLKDSQNTAAILTTFNEIDMSKVIALRNQYKEEFEKKHTVKLGFMSFFVKATIEALKLIPSINAEIDGDDLLYKNYYDIGVAVGTEQGLVVPVIRDADKMSFADIEQAIGNLAKKAREGKLSISDLSGGTFSISNGGVYGSLLSTPIINPPQSGILGLHKTEERAVVIDGKIEIRPMMYIALSYDHRIIDGKEGVSFLVKIKNLIENPEKLLLNL

Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex (EC 2.3.1.61) (2-oxoglutarate dehydrogenase complex component E2) (OGDC-E2) (Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex)

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

398

43,823

Acyltransferase;Lipoyl;Transferase;Tricarboxylic acid cycle

GO:0004149; GO:0005829; GO:0006099; GO:0033512; GO:0045252

Inferred from homology

3

null

PF00198;PF00364;PF02817;

IPR003016;IPR050537;IPR001078;IPR000089;IPR023213;IPR036625;IPR004167;IPR011053;IPR006255;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

sucB RT0170

false

Rickettsia typhi

123

row_251593

false

null

292,065

Q8KT95

MAKAKFERTKPHVNIGTIGHVDHGKTSLTAAITIILAKTGGAKATAYDQIDAAPEEKERGITISTAHVEYETNNRHYAHVDCPGHADYVKNMITGAAQMDGAILVVSAADGPMPQTREHILLAKQVGVPAMVVFLNKVDMVDDPDLLELVEMEVRELLSKYGFPGNEIPIIKGSALQALEGKPEGEKAINELMNAVDSYIPQPIRATDKPFLMPIEDVFSISGRGTVVTGRVESGIIKVGEEIEIVGLKNTQKTTCTGVEMFRKLLDEGQSGDNVGILLRGTKREEVERGQVLAKPGSIKPHDKFEAEVYVLSKEEGGRHTPFTNDYRPQFYFRTTDVTGTIKLPFDKQMVMPGDNATFSVELIKPIAMQEGLKFSIREGGRTVGAGVVTRINN

Elongation factor Tu (EF-Tu) (EC 3.6.5.3)

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

394

42,981

Cytoplasm;Elongation factor;GTP-binding;Hydrolase;Magnesium;Metal-binding;Nucleotide-binding;Protein biosynthesis

GO:0003746; GO:0003924; GO:0005525; GO:0005737; GO:0097216

Inferred from homology

3

SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00118}.

null

PF00009;PF03144;PF03143;

IPR041709;IPR050055;IPR004161;IPR033720;IPR031157;IPR027417;IPR005225;IPR000795;IPR009000;IPR009001;IPR004541;IPR004160;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

tuf RT0653

false

Rickettsia typhi

124

row_276094

false

null

266,820

Q68X19

MTNKTITLNLGPQHPATHGVLRLILEMDGEVVNNADPHIGLLHRGTEKLIEHKTYLQAIPYFDRLDYVSPMCQEHAFALAVESLLECSVPRRAQFIRVLFSELTRILNHTLNIGSQALDIGATTPLLWLFEEREKIMEFYERVSGSRMHANYFRPGGVAEDLPEKLLEDINKFIEQFPSKLNDIENLLNENRLWKQRLVDIGVVSQKDAMDWGFSGPMLRGSGIAWDLRKSNPYDVYDEMDFEVPVGKNGDCYDRYLVRILEMYESIKIIKQCIAKMPKGQVKTDNPKLTPPTREKMKESMEAMIHHFKLYTEGYDVPIGETYKAVEAPKGEFGVYLYSQGGNKPYRCRIKAPGFAHLQGLNFMSKGHLISDVITIIATLDIVFGEIDR

NADH-quinone oxidoreductase subunit D (EC 7.1.1.-) (NADH dehydrogenase I subunit D) (NDH-1 subunit D)

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

389

44,469

Cell inner membrane;Cell membrane;Membrane;NAD;Quinone;Translocase;Transport;Ubiquinone

GO:0005886; GO:0048038; GO:0050136; GO:0051287

Inferred from homology

3

SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-Rule:MF_01358}; Peripheral membrane protein {ECO:0000255|HAMAP-Rule:MF_01358}; Cytoplasmic side {ECO:0000255|HAMAP-Rule:MF_01358}.

null

PF00346;

IPR001135;IPR014029;IPR022885;IPR029014;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

nuoD RT0343

false

Rickettsia typhi

125

row_251573

false

null

266,854

Q68XR3

MKKILGIESSCDDTAISIITESRKILSNIIIPQNTEHAVFGGVVPEIAARSHLSNLDQALENVLTKSNTELTEISAIAATSGPGLIGGVIVGSMFARSLSSALNKPFIAINHLEGHALTVRLTDNISYPYLLLLASGGHCQFVAVLGLGKYKILGSTIDDAIGETFDKVAKMLNLSFPGGPEIEKRAKLGNPHKYKFPKPIINSGNCNMSFSGLKTAVRNLIMSLKEVNDSVINDIAASFQFTIGAILSSKMLNAIRLYQQILNYYYENVDYTTNLNLKSFRQDEFNLNHLQDITRPKSRIYLQNSFRSNLLNDTIVIAGGVAANKYLQEILSNCTQTYGYRLIAPPMHLCTDNAAMIAYAGLERYNNKLFSPLNFCPKAKWSLEDI

tRNA N6-adenosine threonylcarbamoyltransferase (EC 2.3.1.234) (N6-L-threonylcarbamoyladenine synthase) (t(6)A synthase) (t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD) (tRNA threonylcarbamoyladenosine biosynthesis protein TsaD)

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

387

42,546

Acyltransferase;Cytoplasm;Iron;Metal-binding;Transferase;tRNA processing

GO:0002949; GO:0005506; GO:0005737; GO:0061711

Inferred from homology

3

SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01445}.

null

PF00814;

IPR043129;IPR000905;IPR017861;IPR017860;IPR022437;IPR022450;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

tsaD gcp RT0093

false

Rickettsia typhi

126

row_251606

false

null

266,806

Q68WU5

MNIHEYQAKEILRKYGVPTSTGLVVTKTEKINEAIDKLNTKVYVVKAQIHAGGRGKAGGVKVVKSKEEAKKVAHDMFGINLVTHQTGPQGQKVNHLYIESGCDILKEYYFSIVFDRSASCITFIASTEGGVDIEAVAEKMPEKIIKFAVDPATGLQDFHMRGIAYGLGFKDSQAKQMKEIVKSVYNAFIETDATQIEINPLIINSYKNLLALDAKITFDDNGLFKHPNITAMRDHDEEDPLETRAANAGLSYVKMDGNIGCMVNGAGLAMATMDIIKLYGASPANFLDVGGGADRERVKEALKIILSDKEVKGILVNIFGGIMRCDIIAEGIIAAARDIGITVPLVVRLAGTNVEKGKEILSNSNLKIIPAHDLADAANKIVEAIR

Succinate--CoA ligase [ADP-forming] subunit beta (EC 6.2.1.5) (Succinyl-CoA synthetase subunit beta) (SCS-beta)

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

386

41,904

ATP-binding;Ligase;Magnesium;Metal-binding;Nucleotide-binding;Tricarboxylic acid cycle

GO:0000287; GO:0004775; GO:0004776; GO:0005524; GO:0005829; GO:0006099; GO:0006104; GO:0042709

Inferred from homology

3

null

PF08442;PF00549;

IPR011761;IPR013650;IPR013815;IPR017866;IPR005811;IPR005809;IPR016102;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

sucC RT0420

false

Rickettsia typhi

127

row_251559

false

null

266,811

Q68WW7

MKKIILVAGGTGGHFFPAVALGEELIKRGYIVHFITDLRCKKYINKDMKIIFYLLDLKRFSNILLFLPTLLIAFLKSIKLIYHIKSCVIIGFGGYPVIAPMFAAIFLRIPIIIHEQNSYLGKVNKFFARFAKKIAISYEDIKNVPEFAKSKIVLTGGIVRKNIRELDSFIYLASQHCPTKLTKTVLTNTLNHFVKARNNKFSNCNIFTLFIFGGSQGAKLFSELIPASIEILMKKQPNLELKIIQQASLAHQVKIKDIYSKLNITYEFAEFFDNIALQYKVANLVISRAGASTIEELTYIGLPTIFIPLPSAADNHQYYNAKLLADNKAGWCLEQNNISAEKLADQILDLISNRQLLEDAAQNLLNRKQEGHLLLSNLIEDTVFL

UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase (EC 2.4.1.227) (Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase)

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

385

43,548

Cell cycle;Cell division;Cell inner membrane;Cell membrane;Cell shape;Cell wall biogenesis/degradation;Glycosyltransferase;Membrane;Peptidoglycan synthesis;Transferase

GO:0005886; GO:0005975; GO:0008360; GO:0009252; GO:0030259; GO:0050511; GO:0051301; GO:0051991; GO:0071555

Inferred from homology

3

SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-Rule:MF_00033}; Peripheral membrane protein {ECO:0000255|HAMAP-Rule:MF_00033}; Cytoplasmic side {ECO:0000255|HAMAP-Rule:MF_00033}.

null

PF04101;PF03033;

IPR006009;IPR007235;IPR004276;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

murG RT0398

false

Rickettsia typhi

128

row_251564

false

null

266,866

Q68XX8

MKDVILIANAGSSSLKISIFGIQNKKVKDKIYNIFLEKNNNKILFYINQKQESAISIKDNAIEMMINLFEEWWTKQSALNLIATGHRIVHGGKNFNKPVIVNEKIIKELRVLIPLSPLHQPYNLQVLDLFFQKYKDISHIICFDTSFHYTNPPITKAFGLPKQYYDKGIMRYGFHGLSYQYVSSHFKEITMEDLPTKTIIAHLGSGSSLCAIKNGLSLTSSMGFSVLDGVMMATRTGNLDPGVVLYLINHEKMTMKEITELLYKKSGLLGISGESSDMRTLITNNSHDSKFAVELFVYRIVLEIGKLIAALEGIDCIIFTAGIGQNSAVIREMISGKLSWLGIKIDYGKNQKNEHRISTKGSKVKVFVVPTNEELIIAEEVMKFL

Acetate kinase (EC 2.7.2.1) (Acetokinase)

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

385

43,381

ATP-binding;Cytoplasm;Kinase;Magnesium;Metal-binding;Nucleotide-binding;Transferase

GO:0000287; GO:0005524; GO:0005737; GO:0006083; GO:0006085; GO:0008776

Inferred from homology

3

SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00020}.

null

PF00871;

IPR004372;IPR000890;IPR023865;IPR043129;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

ackA RT0026

false

Rickettsia typhi

129

row_251618

false

null

555,567

Q68XT8

MLASYASDPLKSRGRLYKEIPTYYRNEFERDRDRIIHTNAFRRLQYKTQVFINHEEGDHYRNRLTHSLEVATVARSVANTLNLSSDLAETIALAHDLGHTPFGHVGEKALNECMKEYNGFSHNSQSLKILTLLEKRYAAYNGVNLTWEVLEGIVKHNGPILGAINEYVAEYNKQNDLELNTYASAEAQIASLADDISYISHDLEDSIIAKIIDFNNLAELQYIDNYVFKLKSKFKDISPSCLIYEIVRKLIHELITDLLLQTKENLKKEKITNINEIRNLHYQIVDFTEKTNERINETKKFLHKRVYESNKMIAISIKCTKIVQGLFKIYMDDINLLPTNWKILIDSNETYSKARVIADYIAGMTDRFAIQEYNQLCAPKFNKI

Deoxyguanosinetriphosphate triphosphohydrolase-like protein

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

384

44,516

Hydrolase

GO:0006203; GO:0008832

Inferred from homology

1

null

PF01966;PF13286;

IPR006261;IPR050135;IPR023023;IPR003607;IPR006674;IPR026875;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

RT0068

false

Rickettsia typhi

130

row_535578

false

null

266,737

Q68VN9

MYTHYLKNLISFESVTPNSAGAVEYIDGLLKQHGFKTEIKIFGDSKNERVTNLYGVFGSNEPNICFVGHVDVVPAGNHEFWHNSNPFKFHEQDGKIYGRGAVDMKGAIACFLAASLNFIKNNMDFKGSISFLITSDEEGKSTHGTKEMLQYIYDQRYKIDFAVVGEPTCEKEIGDTIKIGRRGSVNFKLNIVGLAGHVAYPHKANNPLPCLIKILNELTNIRLDEGTEFFQNSNLEVTNIDVGNDILNTIPASAEACFNIRFNSLHSVETLSQLIEQIIKQYCKEYKVDYKLEYSSSAESFVQNPNDNDKIKEFADVIERTLKIKSEFSTSGGTSDARFVKDYCSLVEFGLLSEMAHKINEYTKISDLQKLYDVYYNFLMEIF

Succinyl-diaminopimelate desuccinylase (SDAP desuccinylase) (EC 3.5.1.18) (N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase)

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

383

43,330

Amino-acid biosynthesis;Cobalt;Diaminopimelate biosynthesis;Hydrolase;Lysine biosynthesis;Metal-binding;Zinc

GO:0006526; GO:0008270; GO:0008777; GO:0009014; GO:0009089; GO:0019877; GO:0050897

Inferred from homology

3

null

PF07687;PF01546;

IPR001261;IPR036264;IPR005941;IPR002933;IPR011650;IPR050072;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

dapE RT0865

false

Rickettsia typhi

131

row_251491

false

null

310,253

Q9RL99

MENFVFTSESVSEGHPDKIADQISDAVLDEILKHDPNGRVACETFVTTGLVLVGGEITTNTYVDIEQVVRNKIHEIGYNNPSYGFDGSCCAVISSIVKQSPDIAMGIDNANEEEIGAGDQEMVFGYACNETKSLMPAPIYYAHLLMKRQAYLRKQNILSWLRPDAKSQVTLRYENNKPIVIDSVVLSTQHHPEIQQKDLIEAVIEEIIKPTLPTHLLHKDTKYLINPTGRFVIGGPVADCGLTGRKIIVDSYGGMAKHGGGCFSGKDPTKIDRSAAYMARYIAKNIVGSGLADRCEIQISYAIGVASPVSVYAETFGTSKLSNEQTTKLITEHFDMRPGKIIKNLKLHTQCYQKTASYGHFGREDENFTWEQLDKVDIFKSI

S-adenosylmethionine synthase (AdoMet synthase) (EC 2.5.1.6) (MAT) (Methionine adenosyltransferase)

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

382

42,329

ATP-binding;Cytoplasm;Magnesium;Metal-binding;Nucleotide-binding;One-carbon metabolism;Potassium;Transferase

GO:0000287; GO:0004478; GO:0005524; GO:0005737; GO:0006556; GO:0006730

Inferred from homology

3

SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00086}.

null

PF02773;PF02772;PF00438;

IPR022631;IPR022630;IPR022629;IPR022628;IPR002133;IPR022636;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

metK RT0764

false

Rickettsia typhi

132

row_293853

false

null

485,736

Q68WW0

MLKLIVETKTLVQSLGFARSVVEKRNVIPEYANIKLSAKDGNLELSSTNMDLYLSQKIAVQVLSEGEITVSTQTLSDIVRKLPDSELTLTELDIMKLEIKGQNCQFNLFTLPVSSFPAMDSIKPEVSFKISCADFAKIIESTKFSISLDETRYNLNGIYLHIKDKEFFAASTDGHRLSISWITLEEKIKNFGVILPQKSAEEILKIVKDLKNIHEDIEILLSSNKIKFICNENTILLSKLIDGTFPDYSAFIPKSSISKLVINRKIFADSIERIAIITVEKFRAIKLSLSRKTLEISAVGEARGNAKEIITASQDKESFYEYNCDESLVIGFNPQYLEDVLKAVKSNLVELYFSDISASAPVLIKFPQNPKDIFVIMPVKV

Beta sliding clamp (Beta clamp) (Sliding clamp) (Beta-clamp processivity factor) (DNA polymerase III beta sliding clamp subunit) (DNA polymerase III subunit beta)

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

381

42,822

3D-structure;Cytoplasm;DNA replication;DNA-binding;DNA-directed DNA polymerase;Nucleotidyltransferase;Transferase

GO:0003677; GO:0003887; GO:0005737; GO:0006271; GO:0008408; GO:0009360

Evidence at protein level

2

SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:P0A988}.

null

PF00712;PF02767;PF02768;

IPR046938;IPR001001;IPR022635;IPR022637;IPR022634;

6D46;6DJK;

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

dnaN RT0405

false

Rickettsia typhi

133

row_466717

false

null

485,754

Q68X51

MKKIYFIAGEMSGDFIGGHIIQNLKSNEGLEFTGIGGQYMEEAGNFKSLFTITAINFIGFIEIIPHLLKIKKLIDKTVENIINSKVDLLITIDSPGFTYRVAKRVRKFLPNLKIIHIVAPSVWAYKAGRAVDYAKIYDCLFALLPFEPPYFTKVGLDCRYIGHPILEQEFYRDKIALRKEFKIDDNESILCVTFGTRKGEILRHLPIFITAIQKISKDYKNLRIIFPLVHPDHEAIIKPFLENVQFNYLFLSSERLKAYAVSDLALAKSGTNTLEISASGTPMVVAYKVNIISFFIIMFLIKIKYVSLINIMAGSAIIPEFIQFNCRANLISNKLKELLSNSQKRDNQVVESQKILQKLRFASDRSPSYIAAKIIKQEFL

Lipid-A-disaccharide synthase (EC 2.4.1.182)

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

380

43,320

Glycosyltransferase;Lipid A biosynthesis;Lipid biosynthesis;Lipid metabolism;Transferase

GO:0005543; GO:0008915; GO:0009245; GO:0016020

Inferred from homology

2

null

PF02684;

IPR003835;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

lpxB RT0311

false

Rickettsia typhi

134

row_466735

false

null

485,771

Q68XF6

MKLSDFDFNVPNALIAQYPSSERDNSDLLIAGTKHIKTKFYNIIDYLKEGDLLVFNNSKVIKAKLHLGKNITINLNKKLSDNCWGAFAKPARKLNIGDEFYFDTHKIIITEKLAMGEIKVKFILNNISMIKFLDKYGEMPLPFYIKRTSSVCCSNMALFCDHDNTLKITSISHNSNTVNFRSTDSMIDSTNDNDRYQTIYSQIEGSVAAPTAGLHFTKDILDKLKTKGINTAFVTLHVGAGTFLPVKTENIHKHKMHTEYCSITAETAEIINKTKQKGRDIIAVGTTTLRTLESSCNNGIVKAGNFETDIFITPGFNFQIVDMLLTNFHFPKSTLFILICAFAGFKEMHALYKYAIKEKMRFFSYGDATLLYRKV

S-adenosylmethionine:tRNA ribosyltransferase-isomerase (EC 2.4.99.17) (Queuosine biosynthesis protein QueA)

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

375

42,439

Cytoplasm;Queuosine biosynthesis;S-adenosyl-L-methionine;Transferase

GO:0002099; GO:0005737; GO:0008616; GO:0051075

Inferred from homology

2

SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00113}.

null

PF02547;

IPR003699;IPR042118;IPR042119;IPR036100;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

queA RT0204

false

Rickettsia typhi

135

row_466752

false

null

266,839

Q68XI3

MSQDYYQVLGVSKTASQADIKKAYLKLAKQYHPDTTNAHDAEKKFKEINAAYDVLKDEQKRAAYDRFGHDAFQNQQARGGGNNSGFHHDINDIFGDFFSDFMGSGRRKQTSSKIRGSDLKYDLTIKLEEAFHGIEKNISFSSEVKCDACHGTGSEKGETVTTCDSCGGVGVTRIQQGFFTLEQTCHKCQGNGQIIKNPCKKCHGMGRYHKQRNLSINIPAGVENGTRIRHSGEGEAGIRGGNNGDLYVDIAIKPHDIYKIDGANLHCKLPISFVHAALGGEIEVPVIEGGKVKLTIPAGTQNGDQLRLRSKGMSKIRSTIRGDMLTHIHVEVPKNLSKRQRELLEEFKKESINEKENDSSFFNKMKSMWS

Chaperone protein DnaJ

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

370

41,145

Chaperone;Cytoplasm;DNA replication;Metal-binding;Repeat;Stress response;Zinc;Zinc-finger

GO:0005524; GO:0005737; GO:0006260; GO:0008270; GO:0009408; GO:0031072; GO:0042026; GO:0051082; GO:0051085

Inferred from homology

3

SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01152}.

null

PF00226;PF01556;PF00684;

IPR012724;IPR002939;IPR001623;IPR018253;IPR008971;IPR001305;IPR036410;IPR036869;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

dnaJ RT0175

false

Rickettsia typhi

136

row_251592

false

null

485,759

Q68X96

MRAGIENYIKNIEQSLELIWRSLDIESLTIRLTELEELTADPSLWNNNANAQILLREKTNIEEKLNVFNNLKSNFEDILELEAMAEVENDFETLNQIEQDFKKLSIIAAKLETECLFSDESDYNNCFLEINAGAGGTESHDWASIMMRMYLRFAERLGFKTQIINMINGEEVGIKSCTIRIIGKRAYGWFKTEAGVHRLVRISPFNAAGKRMTSFASSWVYPEIDDDIAITIEDKDLRIDTFRASGAGGQHVNTTDSAVRITHIPTNTVTQCQSDRSQHKNKAQAMKMLQAKLYKLEMQKRTDSVDKQNANKTDNSWGHQIRSYVLQPYQIVKDLRTDYETSDTKGVLDGNLENFVSASLAMNASGNKK

Peptide chain release factor 2 (RF-2)

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

369

41,973

Cytoplasm;Methylation;Protein biosynthesis

GO:0005737; GO:0016149

Inferred from homology

2

SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.

null

PF03462;PF00472;

IPR005139;IPR000352;IPR045853;IPR004374;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

prfB RT0265

false

Rickettsia typhi

137

row_466740

false

null

266,770

Q68W26

MSKFSFTIHSNYKKARSGVITTAHGKIRTPTFMPVGTRGTVKAMLTESVVETGADILLGNTYHLMLQPSAERIAYLGGLHKFMNWDKPILTDSGGFQVMSLSKLRKITEEGVSFRSHINGNKYMLTPEYSTEIQYLLGSTITMALDECTPYPSTFEEAKTSMNLTTRWANRSRDAFVKREGYAQFGIIQGSVYKELREQSVKDLVKFDFDGYAIGGLAVGEGQELMFKVLDYVSDFLPQNKPRYLMGVGKPADIIGAVSRGIDMFDCVIPTRSGRNGQAFTKYGTVNIRNSKYAEDKAPLEYDCKCPACTNYTKAYLHHLVRIREILGPMLMTWHNLTYFQNLMSRIRAYIKLGKDFDFVN

Queuine tRNA-ribosyltransferase (EC 2.4.2.29) (Guanine insertion enzyme) (tRNA-guanine transglycosylase)

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

361

40,773

Glycosyltransferase;Metal-binding;Queuosine biosynthesis;Transferase;tRNA processing;Zinc

GO:0002099; GO:0005737; GO:0008479; GO:0008616; GO:0046872; GO:0101030

Inferred from homology

3

null

PF01702;

IPR050076;IPR004803;IPR036511;IPR002616;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

tgt RT0707

false

Rickettsia typhi

138

row_251524

false

null

302,885

Q9AKD8

MLYNLLLPHIHNSHIANLFHYITFRSGLAIIITLSLSFVTGPILIKFLRSLQKYGQPIRSDGPESHQTKAGTPTMGGIMIILSSCISTLLLADLTNKYIWITLFGFISFGIIGFMDDYAKVKRNNHYGVRGKSKFLLQGIISVIIYVLLEYLDKNSSHVLNVPFFKNLSLDLSYFYMVFAIFVIVGSSNAVNLTDGLDGLATVPIAFTAGSFALISYLVGNLIYANYLQLTYIPNTGELTVLCSGLVGSCIGFLWFNAQPAEVFMGDTGSLSLGGVLGIISVITKHEIVLAIIGGLFVIETTSVILQVYYFKATKGKRIFKMAPLHHHFEKHGWAESKVVIRFWIISVIFSLIGLSSLKLR

Phospho-N-acetylmuramoyl-pentapeptide-transferase (EC 2.7.8.13) (UDP-MurNAc-pentapeptide phosphotransferase)

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

361

39,934

Cell cycle;Cell division;Cell inner membrane;Cell membrane;Cell shape;Cell wall biogenesis/degradation;Magnesium;Membrane;Metal-binding;Peptidoglycan synthesis;Transferase;Transmembrane;Transmembrane helix

GO:0005886; GO:0008360; GO:0008963; GO:0009252; GO:0046872; GO:0051301; GO:0051992; GO:0071555

Inferred from homology

3

SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-Rule:MF_00038}; Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_00038}.

null

TRANSMEM 28..48; /note="Helical"; /evidence="ECO:0000255|HAMAP-Rule:MF_00038"; TRANSMEM 74..94; /note="Helical"; /evidence="ECO:0000255|HAMAP-Rule:MF_00038"; TRANSMEM 99..119; /note="Helical"; /evidence="ECO:0000255|HAMAP-Rule:MF_00038"; TRANSMEM 133..153; /note="Helical"; /evidence="ECO:0000255|HAMAP-Rule:MF_00038"; TRANSMEM 168..188; /note="Helical"; /evidence="ECO:0000255|HAMAP-Rule:MF_00038"; TRANSMEM 203..223; /note="Helical"; /evidence="ECO:0000255|HAMAP-Rule:MF_00038"; TRANSMEM 236..256; /note="Helical"; /evidence="ECO:0000255|HAMAP-Rule:MF_00038"; TRANSMEM 263..283; /note="Helical"; /evidence="ECO:0000255|HAMAP-Rule:MF_00038"; TRANSMEM 288..308; /note="Helical"; /evidence="ECO:0000255|HAMAP-Rule:MF_00038"; TRANSMEM 338..358; /note="Helical"; /evidence="ECO:0000255|HAMAP-Rule:MF_00038"

PF00953;PF10555;

IPR000715;IPR003524;IPR018480;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

mraY RT0583

false

Rickettsia typhi

139

row_286684

false

null

485,800

Q68XQ6

MKNIFLHSLNLENYRNFKNLELKIDNIPIILTGENGSGKTNILEAISLFYPGRGLRSSKLTDICKTSEDYCRVKALLQSKLGIADFSTHIKRNSNRRITEYNASKIANNELSKFTSMVWLTPQMEGIFTSSSTDRRKFLDRIVYNFDTKHAELLNKYEYYMHERNKILAEDIRDNNWLKIIEENMANISNIIANNRLKTIRFMQQAIDEIENEFPKADLSIDGIIEQKILNVEEDIVSFIITELYQTRSKDKLLGRTSFGIHKSDFLVKHQKKNILAKFCSTGEQKAILIAIILAEMNSTIKLTKITPILLLDEIFVHLDDKRRQYLMDFFTALNIQLWVTATNLDGIENFANKAQLIKL

DNA replication and repair protein RecF

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

360

41,725

ATP-binding;Cytoplasm;DNA damage;DNA repair;DNA replication;DNA-binding;Nucleotide-binding;SOS response

GO:0000731; GO:0003697; GO:0005524; GO:0005737; GO:0006260; GO:0006302; GO:0009432

Inferred from homology

2

SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00365}.

null

PF02463;

IPR001238;IPR018078;IPR027417;IPR003395;IPR042174;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

recF RT0100

false

Rickettsia typhi

140

row_466781

false

null

266,824

Q68X66

MATIVVAMSGGVDSSAVAAMLHEQGHHVIGITLQLYDYGIAVGKKNACCAGKDIYDAKMVANKLGIPHYVLDYENKFKESVIDNFVNSYLHGETPLPCVQCNKLVKFRDLINTAKELGADKLATGHYVRKINGYNGAELHTGLDAAKDQSYFLFTITREQLEYLIFPLGGFTKYETRKLASKFGLDVADKPDSQDICFVPDGNYKTVINKIRPEASTSGKIVHINGFELGEHSGIINYTIGQRRGLGIAYNEPLYVVKIDPSNNIVYVGQESALHVHEFIIKDVNWLADEIKDNEKLAVDVKIRSTRPPCHAEISKLCNDKIKVQFLSAEKAVAPGQACVIYAGERVLGGGWITRNIR

tRNA-specific 2-thiouridylase MnmA (EC 2.8.1.13)

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

358

39,536

ATP-binding;Cytoplasm;Disulfide bond;Nucleotide-binding;RNA-binding;Transferase;tRNA processing;tRNA-binding

GO:0000049; GO:0002143; GO:0005524; GO:0005737; GO:0103016

Inferred from homology

3

SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00144}.

null

PF03054;PF20258;PF20259;

IPR004506;IPR046885;IPR046884;IPR023382;IPR014729;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

mnmA trmU RT0296

false

Rickettsia typhi

141

row_251577

false

null

485,721

Q68WK7

MSFSDNLVKILDKYENLGRKLSSGIIGDEFVKASKEYAELEDIVVKIKEYNKVKSELEEANNLRLEVALDNATLEMINNEIYILENLLPKLERAVRISLLPKDEADSKSAIIEVRAGSGGEEAALFAAVLFNMYQRYAEFKGWRFEILAISNTGIGGYKEASASIKGKDVFSKLKFESGVHRVQRVPETESQGRIHTSAATVAVLPEAEGVDIKIEDKDLRIDTYRSSGAGGQHVNTTDSAVRITHIPTGITVALQDEKSQHKNKAKALKILRARLYEEKRRQKEQERSDSRRWQVGSGDRSERIRTYNFLHGRVSDHRINLTLYKIDEVVKHGQLDEFIEALIANDEAKKLSEL

Peptide chain release factor 1 (RF-1)

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

355

40,062

Cytoplasm;Methylation;Protein biosynthesis

GO:0005737; GO:0016149

Inferred from homology

2

SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00093}.

null

PF03462;PF00472;

IPR005139;IPR000352;IPR045853;IPR050057;IPR004373;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

prfA RT0516

false

Rickettsia typhi

142

row_466702

false

null

266,809

Q68WW2

MANIETILKLAEEKILLVHNLKDLQEYKVEFLGKNGIVTSELKKLSSLVNGQERKEFGLKINTLKDKIHNIIKAKVQILEEEELNLKLAADKIDLTIPARRYKQGSIHPITQCMDELIQVFAQFGFTIENGPNIENDFHNFTALNFEYDHPARQMHDTFYLKGRENDKPLLLRTHTSTVQIRAMKNGKPPFRFIAPGRTYRSDSDMTHTPMFHQIEGLVIDKNINMGHLKYVIIKFIRSFFENPNIELRFRPSFFPFTEPSAEVDIRMNKNDKWLEVLGCGMVHPNVLKNVGIDRSEYQGFAFGLGVERFAMLKYNIKDLRRFFEGDIRWLKHYNFESFDIPNLAGGLTK

Phenylalanine--tRNA ligase alpha subunit (EC 6.1.1.20) (Phenylalanyl-tRNA synthetase alpha subunit) (PheRS)

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

350

40,708

Aminoacyl-tRNA synthetase;ATP-binding;Cytoplasm;Ligase;Magnesium;Metal-binding;Nucleotide-binding;Protein biosynthesis

GO:0000049; GO:0000287; GO:0004826; GO:0005524; GO:0005737; GO:0006432

Inferred from homology

3

SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00281}.

null

PF02912;PF01409;

IPR006195;IPR045864;IPR004529;IPR004188;IPR022911;IPR002319;IPR010978;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

pheS RT0403

false

Rickettsia typhi

143

row_251562

false

null

485,827

Q68XX7

MKKQHIINETFLDEILAQKLGTTYIPPTGIKDADFEQAAKHFINLLLRADGLKPIKTAVVHPIDKESLLGAVRAAQFNVIKPVLIGPQHKIESVAKVNDVDLENYQVINAEHSHEAAKKAVELAKKREVSAIMKGALHTDELMSAVVYKENGLRTERRISHAFLMAVATFPKPFIITDAAINIRPTLEDKRDIVQNAIDLMHMIKEDKQVRVAVLSAVETVTSAIPTTLDAAALSKMADRGQIMNAIVDGPLAFDNAISLFAAEAKGINSPVSGNADILVAPDLESGNLLAKQLKYLGQAVMAGIVLGARVPIILTSRADPIDMRVISCVLASFIYNQTKAKLHIQASQ

Phosphate acetyltransferase (EC 2.3.1.8) (Phosphotransacetylase)

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

349

37,938

Acyltransferase;Cytoplasm;Transferase

GO:0005737; GO:0006085; GO:0008959

Inferred from homology

2

SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.

null

PF01515;

IPR012147;IPR050500;IPR002505;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

pta RT0027

false

Rickettsia typhi

144

row_466806

false

null

485,833

Q68XZ4

MVSSNFYKNLGPRKLTAIIDFLHDIIEPTKIHEDIDIHDIKILQEASPNDISFLSNPKYSEFLKTTKAAACIVPKDFTEESNQNTVLIHAENSYFAYSKLIDFFYAPIKSYSTKIMKSAIIADSAAIGKNCYIGHNVVIEDDVIIGDNSIIDAGTFIGRGVNIGKNARIEQHVSINYAIIGDDVVILVGAKIGQDGFGFATEKGVHNKIFHIGIVKIGNNVEIGSNTTIDRGALQDTIIEDLCRIDNLVQIGHGVKIGKGSIIVAQAGIAGSSAIGKYCALGGQVGIAGHLNIGDRTQVAAQGGVAQNIEEGKIVGGSPAVPIMDWHRQSIIMKQLVKTSNNKLKK

UDP-3-O-acylglucosamine N-acyltransferase (EC 2.3.1.191)

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

346

37,251

Acyltransferase;Lipid A biosynthesis;Lipid biosynthesis;Lipid metabolism;Repeat;Transferase

GO:0009245; GO:0016020; GO:0016410

Inferred from homology

2

null

PF00132;PF04613;

IPR001451;IPR018357;IPR007691;IPR011004;IPR020573;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

lpxD RT0008

false

Rickettsia typhi

145

row_466812

false

null

266,733

Q68VM8

MKQISNSLRNSNKIPIWFMRQAGRYLPEYKKVRETTKNFLDFCFDVNKATEVTLQPIRRYGLDAAIIFSDILVLPSALGWEVDFKENIGPVLKQFKSQKDFQYLQRDSNNKLENVFKIIKKVKEKLPSNTSLIGFAGSPWTVMSYMLEGKGKRDFITSKKFVYENKILAKDLLNFITEKTADYLINQAKSGADILKIFDSWSGVLAEDDFTEFVIEPTKKIILKVKEVFINIPIITFPKGAGLLYEKFIKEVPIDILAVDQMVPLEKMKEWSNKVIVQGNLDPVVLLTNKEIIEEKTYKILQGMKGKNFIFNLGHGILPETPPENVEFLTKYIRLYEKKNSNSTF

Uroporphyrinogen decarboxylase (UPD) (URO-D) (EC 4.1.1.37)

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

345

39,806

Cytoplasm;Decarboxylase;Lyase;Porphyrin biosynthesis

GO:0004853; GO:0005829; GO:0006782

Inferred from homology

3

SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00218}.

null

PF01208;

IPR038071;IPR006361;IPR000257;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

hemE RT0877

false

Rickettsia typhi

146

row_251487

false

null

266,734

Q68VM9

MKKRIAIVLFNLGGPEDIEYVKPFLFNLFYDKAIINLPNPLRYVIAKIISIVRERKSQKIYSLIGRKSYLIQETEKQKLAITKKLKEILKEDFIIFISMRYSTPFAKEVICQIKEYNPSEIILLPLYPQFSSTTTGSSVKNFLQNIDIDIPIKTICCYPIEEDFIKAHVSIIKEKLYDKNFRILFSAHGLPKRIIKAGDPYSFQIKETVNKIVKELNIKDLDYKITYQSRVGPIEWLKPSTEYEIELAGKLKKDIIIVPISFVSEHVETLVELDIEYKFIADKYNIQYTRIPTLGTNKIFINSLTNILIRFINKTDTNLVMSSSSKRICPNKFTKCLCNLIN

Ferrochelatase (EC 4.98.1.1) (Heme synthase) (Protoheme ferro-lyase)

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

342

39,758

Cytoplasm;Heme biosynthesis;Iron;Lyase;Metal-binding;Porphyrin biosynthesis

GO:0004325; GO:0005737; GO:0006783; GO:0046872

Inferred from homology

3

SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00323}.

null

PF00762;

IPR001015;IPR019772;IPR033644;IPR033659;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

hemH RT0876

false

Rickettsia typhi

147

row_251488

false

null

266,801

Q68WS6

MLEEQNSDIERKQDHIEINLKQNVNSTLKSGLASIKFIHNALPEINYDNIDTTTTFLGKYMKAPILISSMTGGTTRAKDINYRLAQAAQKSGIAMGLGSMRILLTKPDTIKTFTVRHVAPDIPLLANIGAVQLNYGVTPKECQYLIDTIKADALILHLNVLHELTQPEGNRNWENLLPKIKEVINYLSVPVIIKEVGYGLSKQVAKKLIKVGVKVLDIAGSGGTSWSQVEAYRAKNSMQNRIASSFINWGITTLDSLKMLREVSKDITLIASGGLQSGIDGAKAIRMGANIFGLAGQLLKAADIAESLVSEEIQLIIEQLKITMLCTGSCTLKDLAKAEIML

Isopentenyl-diphosphate delta-isomerase (IPP isomerase) (EC 5.3.3.2) (Isopentenyl diphosphate:dimethylallyl diphosphate isomerase) (Isopentenyl pyrophosphate isomerase) (Type 2 isopentenyl diphosphate isomerase) (IDI-2)

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

342

37,359

Cytoplasm;Flavoprotein;FMN;Isomerase;Isoprene biosynthesis;Magnesium;Metal-binding;NADP

GO:0000287; GO:0004452; GO:0005737; GO:0008299; GO:0010181; GO:0016491; GO:0070402

Inferred from homology

3

SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00354}.

null

PF01070;

IPR013785;IPR000262;IPR011179;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

fni RT0439

false

Rickettsia typhi

148

row_251554

false

null

266,814

Q68WZ0

MTNILSPEKSENDQELPIRPSYLQEFVGQQQIKENLLVFIKAAKSRNEHLDHTLFYGPPGLGKTTLAKIISNEIGGNFKSTAGPAIIKAADLAAILTNLEKNDVLFIDEIHRLNTLVEEILYSAMEDFELDIIIGEGSAARSVKITLPKFTLIGATTRFGMLSNSLRDRFGIPMRLNFYNTEELKQVLNRASKLLDIDLTDSGSEEIAKRSRGTPRIALRLLRRIRDFAVVDGKLRIDKEICDFGLKRLTVDSIGLDSNDYRYLKFIADNYHGGPVGIETIAAALSEQRDELEETIEPYLIKIGLVKRTPRGRVITIAAFEHLKMPIPNKSQHQFNILNENE

Holliday junction branch migration complex subunit RuvB (EC 3.6.4.-)

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

342

38,491

ATP-binding;Cytoplasm;DNA damage;DNA recombination;DNA repair;DNA-binding;Hydrolase;Nucleotide-binding

GO:0000400; GO:0005524; GO:0005737; GO:0006281; GO:0006310; GO:0009378; GO:0016887; GO:0048476

Inferred from homology

3

SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00016}.

null

PF17864;PF05491;PF05496;

IPR003593;IPR041445;IPR004605;IPR027417;IPR008824;IPR008823;IPR036388;IPR036390;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

ruvB RT0375

false

Rickettsia typhi

149

row_251567

false

null

509,200

Q8L2J6

MFVDKTLMITGGTGSFGNAVLSRFLKSNIINDIKEIRIFSRDEKKQEDMRIALNHSKLKFYIGDVRNYQSIDDAMHGVDYVFHAAALKQVPTCEFYPMEAINTNVLGAENVLSAAINNKVTKVIVLSTDKAVYPINAMGLSKALMEKLAIAKARMRSPGETILCVTRYGNVMASRGSVIPLFIHQIKQGKELTITEPSMTRFLMSLVDSVDLVLYAFEHGRQGDIFVQKSPASTIEVLAKALQEIFGSKNAIRFIGTRHGEKHYESLVSSEDMAKADDLGGYYRIPMDGRDLNYAKYFVEGEKKVALLKDYTSHNTKRLNLKEVKELLLTLDYVQEELKNA

UDP-glucose 4-epimerase (EC 5.1.3.2) (Galactowaldenase) (UDP-galactose 4-epimerase)

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

341

38,278

Isomerase;Lipopolysaccharide biosynthesis

GO:0003978; GO:0009103

Inferred from homology

2

null

PF08485;PF02719;

IPR013692;IPR036291;IPR003869;IPR051203;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

capD RT0323

false

Rickettsia typhi

150

row_489796

false

null

266,761

Q68VY8

MSNTDKERAIAAALAQIEKSYGKGSVMKLGQRPNIDIEAISTGSLGLDIALGIGGVPKGRIIEIFGPESSGKTTLTLHLIAESQKNGGTCAFIDAEHALDPAYAKKLGVNIDELIISQPDTGEQALEIADTLIRSGGIDMIIIDSVAALVPKSEIEGEMGDAQMASQARLMSQALRKLTASINRTNCITVFINQIRMKIGVMFGSPETTTGGNALKFYASVRIDIRRIGSIKDKEEVIGSQTKVKVVKNKVSPPFKTADFDIMYGSGISKEGEIIDLGVKLEIIEKSGSWFAYNKVRIGQGRENVKQYLKEHPQIANEIEKIIREKSSAITNINLDQTEE

Protein RecA (Recombinase A)

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

340

36,807

ATP-binding;Cytoplasm;DNA damage;DNA recombination;DNA repair;DNA-binding;Nucleotide-binding;SOS response

GO:0003684; GO:0003697; GO:0005524; GO:0005829; GO:0006281; GO:0006310; GO:0009432; GO:0016887; GO:0140664

Inferred from homology

3

SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00268}.

null

PF00154;PF21096;

IPR003593;IPR013765;IPR020584;IPR027417;IPR049261;IPR049428;IPR020588;IPR023400;IPR020587;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

recA RT0747

false

Rickettsia typhi

151

row_251515

false

null

266,779

Q68WA2

MLSLSKNWNTLIKPNRVTYENFPETNNKAKIIVEPLERGFGLTLGNAMRRVLLSSLQGAAITSIKIPAIEHEFSSIPGVQEDVSEVILNIKGIEVKMHVSEKRIMKLKATGPCVVTAGMIDTGHDVEILNPNHVICNLAKNKQLEMELTCKVGKGYVLSTNSYEDNLPIGEIAIDALFNPVKSVTYKVENTRVGQVTDYDKLIIFVETNGDVLPEMAVGLAARILQEQLQLFIAFEEQEEDKQVKTDSLPFSPYLLKRVDELELSVRSANCLKNDNIIYIGDLVKRTESDMLRTPNFGRKSLNEIKEILAKFNLRFGMDVPDWPPENIQELSKRYEDSYN

DNA-directed RNA polymerase subunit alpha (RNAP subunit alpha) (EC 2.7.7.6) (RNA polymerase subunit alpha) (Transcriptase subunit alpha)

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

340

38,329

DNA-directed RNA polymerase;Nucleotidyltransferase;Transcription;Transferase

GO:0000428; GO:0003677; GO:0003899; GO:0005737; GO:0006351; GO:0046983

Inferred from homology

3

null

PF01000;PF03118;PF01193;

IPR011262;IPR011263;IPR011773;IPR036603;IPR011260;IPR036643;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

rpoA RT0627

false

Rickettsia typhi

152

row_251533

false

null

266,752

Q68VV3

MIELFYEYMFPLTVIALKVVAITIPLILCVAYLTYAERRVIGLMQLRRGPNVVGPFGLLQPIADAVKLLFKEPIIPTNADKILFILAPIITFVLSLIGWAVIPFAKGVVLADINVGVLYILAISSLSVYGIIIAGWASNSKYAFLGAIRSSAQMISYEVSIGLVIVTVLLTTGTLNLSRIIEAQKTLPWWIDLMLLPMSIVFFISVLAETNRLPFDLPEAESELVAGYNVEYSSMGFALFFLGEYANMILVSAMTTTFFLGGYLPPFNLPFLDCIPGFFWFVLKVMLLLFCFLWIRATLPRYRYDQLMRLGWKVFLPLTLFGVVLVSSVLFYTDNLPSV

NADH-quinone oxidoreductase subunit H (EC 7.1.1.-) (NADH dehydrogenase I subunit H) (NDH-1 subunit H)

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

339

37,923

Cell inner membrane;Cell membrane;Membrane;NAD;Quinone;Translocase;Transmembrane;Transmembrane helix;Ubiquinone

GO:0003954; GO:0005886; GO:0009060; GO:0016655; GO:0048038

Inferred from homology

3

SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-Rule:MF_01350}; Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01350}.

null

TRANSMEM 10..30; /note="Helical"; /evidence="ECO:0000255|HAMAP-Rule:MF_01350"; TRANSMEM 50..70; /note="Helical"; /evidence="ECO:0000255|HAMAP-Rule:MF_01350"; TRANSMEM 82..102; /note="Helical"; /evidence="ECO:0000255|HAMAP-Rule:MF_01350"; TRANSMEM 115..135; /note="Helical"; /evidence="ECO:0000255|HAMAP-Rule:MF_01350"; TRANSMEM 155..175; /note="Helical"; /evidence="ECO:0000255|HAMAP-Rule:MF_01350"; TRANSMEM 187..207; /note="Helical"; /evidence="ECO:0000255|HAMAP-Rule:MF_01350"; TRANSMEM 235..255; /note="Helical"; /evidence="ECO:0000255|HAMAP-Rule:MF_01350"; TRANSMEM 275..295; /note="Helical"; /evidence="ECO:0000255|HAMAP-Rule:MF_01350"; TRANSMEM 311..331; /note="Helical"; /evidence="ECO:0000255|HAMAP-Rule:MF_01350"

PF00146;

IPR001694;IPR018086;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

nuoH RT0783

false

Rickettsia typhi

153

row_251506

false

null

91,798

Q68X56

MTKKYNIAVIGATGNVGRETLNILAERHFPINKIYAIASNNSLGREVRFGAKILHINSLTIFNFYDIDIAFFCAGSNVSKEFIPKATADNCIVIDKTSLFRTDNQVPLIVPEANLSTLKEFNTKNIIANPNCIVIPLVVALKPLDNEIKIKRVVISTYQSVSGAGKAGMDELYDQTKSKYVFRENNPQKFPKQIAFNLFPHIGDFNKDGYTTEETKIAFELSKIMGTHFKTSVTSVRVPVFIGHAISVNIEFSNKIYAKDVEEILQDADGIVTISNNNDLAYISPIEVVGKDAVYVSRIRNDLSKENTINLWITCDNLRKGAALNSVQIAEELINNYL

Aspartate-semialdehyde dehydrogenase (ASA dehydrogenase) (ASADH) (EC 1.2.1.11) (Aspartate-beta-semialdehyde dehydrogenase)

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

338

37,675

Amino-acid biosynthesis;Diaminopimelate biosynthesis;Lysine biosynthesis;Methionine biosynthesis;NADP;Oxidoreductase;Threonine biosynthesis

GO:0004073; GO:0009088; GO:0009089; GO:0009097; GO:0019877; GO:0046983; GO:0050661; GO:0051287; GO:0071266

Inferred from homology

4

null

PF01118;PF02774;

IPR012080;IPR005986;IPR036291;IPR000534;IPR012280;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

asd RT0306

false

Rickettsia typhi

154

row_81502

false

null

485,724

Q68WM0

MYNTDIVIIGSGPVGLFAVFQAGMLGMKCHVIDAQEVIGGQCITLYPEKHIYDIPAYPKITAKELIEQLKSQAAPFNPVYHLNQQAIELNKHNDFFEIKTSKNTIIKSKVIIIAAGAGAFGPNKPPLANIEDFEGKSIFYFINDKSKFLGKNIVVAGGGDSAVDWTIALSEIANKIYLVHRRDKFTAATESIRQLRHIAETGKIELVTGYQLNNLDGHNNELQAVIVKDLQNNIRKLDANILLPFFGLKQDLGPLANWGLNVKLQHIEVDNYYYQTNIKGIYAIGDVAHYVGKLKLIITGFAEAAHSINHAYSRVFDGKALHFEYSTNKYEQKQ

Ferredoxin--NADP reductase (FNR) (Fd-NADP(+) reductase) (EC 1.18.1.2)

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

334

37,235

FAD;Flavoprotein;NADP;Oxidoreductase

GO:0004324; GO:0050660; GO:0050661

Inferred from homology

2

null

PF07992;

IPR036188;IPR023753;IPR022890;IPR050097;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

RT0500

false

Rickettsia typhi

155

row_466705

false

null

485,738

Q68WY2

MQKFLSLIIVILILYNIVKLKIYPEDNNNSTTIEQITSNNSSTNAHQASINNEPTISLNGNLFERTVSKIVINALKTEEGKVFFENILQPLNGPINPNDYTIEVHKDLVKTLFKINTFGSGNIGPASCGHVVTVFYQISDMNNNLISEDTKTFTLGSAPVMLGLDNVIIGMMVGESREAIIPAKYTVNNSNNTIFDDAYNYKVTVILKSILPQNFVKSNKVKIYDDEIAYRVPLLCGEKVSFNAKITRLSNGKILFDSKSTGQPIDMKIGDITYPLIFSYALQGKVQVGTRSVIAESKTFKALGSNLNKVIPHESLPIHEYLLLELNDFKQIK

Putative peptidyl-prolyl cis-trans isomerase RT0383 (PPIase RT0383) (EC 5.2.1.8) (Rotamase RT0383)

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

333

37,058

Isomerase;Rotamase

GO:0003755; GO:0006457

Predicted

2

null

PF00254;

IPR046357;IPR001179;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

RT0383

false

Rickettsia typhi

156

row_466719

false

null

266,742

Q68VS1

MHFIDEVKIYIKGGNGGNGCISFHREKFVDRGGPDGGDGGFGGSVIFRSNHHINTLVNYRYQQHFIAENGGNGKGSNRSGKSGKSLILDVPIGTQIFSEDGNILLHDFTEDEKSFEIIKGGCGGLGNSHFKTSVNQAPRKRTEGEIAQEMWIHLRLKLLSDVGLVGLPNAGKSTFLSVVTAAKPKIADYPFTTLVPNLGVVYINDEEFVIADIPGLIAGAHQGHGLGDKFLKHIERCNVLIHLIDGSSHNVIADYDTVRFELESYSDYLKNKIEIICINKCDVLTDEEIQKKIKKLQRVTNKVVHPISTYTNLGVNKIVKLALEIIKNQI

GTPase Obg (EC 3.6.5.-) (GTP-binding protein Obg)

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

330

36,321

Cytoplasm;GTP-binding;Hydrolase;Magnesium;Metal-binding;Nucleotide-binding

GO:0000287; GO:0003924; GO:0005525; GO:0005737; GO:0042254

Inferred from homology

3

SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01454}.

null

PF01018;PF01926;

IPR031167;IPR006073;IPR014100;IPR006169;IPR036726;IPR045086;IPR027417;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

obg RT0831

false

Rickettsia typhi

157

row_251496

false

null

485,729

Q68WR2

MKKTVLSGVQTTGALHLGNYLGSIKNWVKMQEEYNCFFFLADLHAITIDIKTSELNNSIMEVLAIYLAAGLNPDKVTIFAQSMVKEHAELSWLLNCVTPLGWLKRMTQFKDKAGSDQCKACLGLFAYPILMAADILIYKADIVPVGEDQKQHLELTRDIAEVINRRFDKEILKVPDILISETGTRIMSLRNGLKKMSKSDIADFSRINLKDSNDLIYQKIKKAKTDHLSFISYDKKTRPEISNLLDIYKSLSKESMEKIINNYQNQGFAKFKEDLAEIIITNLQPIRDKCLELMNDKEYLLKILHKGAEKAKIRASETVNEVKKQFGFII

Tryptophan--tRNA ligase (EC 6.1.1.2) (Tryptophanyl-tRNA synthetase) (TrpRS)

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

330

37,661

Aminoacyl-tRNA synthetase;ATP-binding;Cytoplasm;Ligase;Nucleotide-binding;Protein biosynthesis

GO:0004830; GO:0005524; GO:0005737; GO:0006436

Inferred from homology

2

SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00140}.

null

PF00579;

IPR002305;IPR014729;IPR002306;IPR024109;IPR050203;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

trpS RT0455

false

Rickettsia typhi

158

row_466710

false

null

485,832

Q68XZ3

MIKIGNIELSSNVILAPMSNITDLEFRKLVKRFGAGLVVSEMIASRAMIMKSRQSMQKCAIMHDDPTSACVQLAGCEPDVIADAAKMNEDMGAKIIDLNFGCPAKKVVGGYAGSALMRDERLATKIFEATVKAVKIPVTVKMRMGWDDNTKNAPTLAVIAASSGVQMVTVHGRTRCQFYSGNANWDFIRVVKEAVKIPVIANGDITNFAKAKEALQKSGADGIMVGRGVYGKPWLISQIAYYLKTGKEKPAPSIAEQLDIIIKHYDAIIDYYGKSVGVPIARKHIIWYSSGLPSSAEFRCAVNLMNDPIAVKEKIAEFYMSVMDANK

Probable tRNA-dihydrouridine synthase (EC 1.3.1.-)

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

327

35,691

Flavoprotein;FMN;NADP;Oxidoreductase;RNA-binding;tRNA processing;tRNA-binding

GO:0000049; GO:0017150; GO:0050660

Inferred from homology

2

null

PF01207;

IPR013785;IPR035587;IPR001269;IPR004652;IPR024036;IPR018517;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

dus RT0010

false

Rickettsia typhi

159

row_466811

false

null

485,760

Q68XA8

MQITVREALRDAMQEEMLRDDKVFVIGEEVAEYQGAYKVTQGLLEQFGSKRVIDTPITEYGFAGLAVGAAFAGLRPIVEFMTFNFAMQAFDHIVNSAAKTHYMSGGQVKCPIVFRGPNGAASRVAAQHSQNYTACYSHIPGLKVVAPYSAEDHKGLMLTAIRDDNPVIFLENEILYGHSFDVPDIIEPIPFSKAKILKEGSNVTIVTFSIQVKLALDVVNILQNDNIDCELIDLRTIKPLDTNMIIESVKKTNRLVIVEEGWFFAGVGASIASIVMKEAFDYLDAPIEIVSGKDVPLPYAVNLEKLAMPSANDLIEAVKKVCYYTI

Pyruvate dehydrogenase E1 component subunit beta (EC 1.2.4.1)

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

326

35,961

Oxidoreductase;Pyruvate;Thiamine pyrophosphate

GO:0004739; GO:0006086

Inferred from homology

2

null

PF02779;PF02780;

IPR027110;IPR029061;IPR009014;IPR005475;IPR033248;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

pdhB RT0253

false

Rickettsia typhi

160

row_466741

false

null

485,761

Q68XA9

MNIKPKKYKPIKEEYIKSFKDMLLLRRFEEKCGQLYGMGEIGGFCHLYIGQEAVISAVELIKKKGDSTITSYRDHAHIILAGTEPKYVLAELMGRATGCSKGKGGSMHLFDIPNKFYGGHGIVGAQVPIGTGLAFAEKYNGTNNICFTFLGDGAVNQGQVYEAFNMASLWGLPVVYIIENNEYSMGTSVSRSTFMRDLYKKGESFGIRGFQLDGMDFEEMYNGTKQVAEYVRENSFPVILEVKTYRYRGHSMSDPAKYRSKEEVAKYKERDTLVRIRQIILDNKYATEEDLKAIERSVQEVIKVAVEFSENSPLPSEDELYTDIYV

Pyruvate dehydrogenase E1 component subunit alpha (EC 1.2.4.1)

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

326

36,905

Oxidoreductase;Pyruvate;Thiamine pyrophosphate

GO:0004739; GO:0006086; GO:0043231

Inferred from homology

2

null

PF00676;

IPR001017;IPR050642;IPR017597;IPR029061;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

pdhA RT0252

false

Rickettsia typhi

161

row_466742

false

null

266,830

Q68XC0

MNKYQTHLLEHSVVKILSGTGKKHIALVAGGMSAEREVSLISSVGVSKALIELGYKVTFIDMGADIAVKLQEINPDIVFNCLHGTYGEDGCLPGLLNIMRIPYTHSGVLSSALAFDKIHSRSCFLKNNINMADSIVVSKSDHINTDPMKRPYVIKPLKQGSSIGVEVIFEEDDFHFIDYDFPYGEDIIIEQYIQGQELQVALLNGKALGVLEIKLLKNRFYDYETKYNKGFAKHVCPAQLPANLYKKLLIESEKIYKTINCKGPVRAEFILEEQTNKLYVLEINTHPGMTPLSIVPEIAAYAGISFTNLIEEIIKMASFES

D-alanine--D-alanine ligase (EC 6.3.2.4) (D-Ala-D-Ala ligase) (D-alanylalanine synthetase)

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

321

35,822

ATP-binding;Cell shape;Cell wall biogenesis/degradation;Cytoplasm;Ligase;Magnesium;Manganese;Metal-binding;Nucleotide-binding;Peptidoglycan synthesis

GO:0005524; GO:0005737; GO:0008360; GO:0008716; GO:0009252; GO:0046872; GO:0071555

Inferred from homology

3

SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00047}.

null

PF07478;PF01820;

IPR011761;IPR013815;IPR000291;IPR005905;IPR011095;IPR011127;IPR016185;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

ddl RT0241

false

Rickettsia typhi

162

row_251583

false

null

423,841

P58188

MIKLLYPQFWQERNIIAYLLLPISLIYQFLSYLRTSLACPVILPAKVICVGNCSVGGTGKTQIVIYLAKLLKAKNVSFVIITKAYGSNIKSTTIIQKWHTALEVGDEGIMLAKYGTAIAAKHIKDILPLINELKPDVIIVDDFLQNPYLHKDFTIVSVDSQRLFGNRFLIPAGPLRQNPKQVLDAADLIFLVSSNQDQIPNELTPYIDKVINAQIVPSNNIDKTKNYFAFSGIGNPQRFFLTLENYRLNIVGHKTFPDHYNYLQADLENLYSLAKEHNAILITTRKDYVKFNYLNNKIICLDVELSINNPDLLNEKIFKKA

Tetraacyldisaccharide 4'-kinase (EC 2.7.1.130) (Lipid A 4'-kinase)

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

321

36,434

ATP-binding;Kinase;Lipid A biosynthesis;Lipid biosynthesis;Lipid metabolism;Nucleotide-binding;Transferase

GO:0005524; GO:0005886; GO:0009029; GO:0009244; GO:0009245

Inferred from homology

2

null

PF02606;

IPR003758;IPR027417;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

lpxK RT0705

false

Rickettsia typhi

163

row_405964

false

null

266,804

Q68WT6

MNKFKNIAVYGGGSFGTSLASVVARNCNNVTLFLRNETILKEILYKKTNVQYLGDIKLPTNLQATTNLSVIKDFDLIIIAVPSYAFVDAIKLLKTYGISKDNTLLVATKGFAHNPTELLSDRLNTLLPDNPIGFLSGPNLAKELAKNLHTSASIASLDIDIANKIAHNLSSKTFTTNTTIDIVTLQVAGALKNIFAIKSGIDLAREQGANSRAMLIVAALKEITTLSKVLGGMQKNSDILLEAGVVGDLVLTCYSLGSRNTKFGYEFEISMDKKKFLREYKELVEGREALKLVLDLIKKYNLHMPIVSEVASLIHCGIYI

Glycerol-3-phosphate dehydrogenase [NAD(P)+] (EC 1.1.1.94) (NAD(P)(+)-dependent glycerol-3-phosphate dehydrogenase) (NAD(P)H-dependent dihydroxyacetone-phosphate reductase)

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

320

34,971

Cytoplasm;Lipid biosynthesis;Lipid metabolism;NAD;NADP;Nucleotide-binding;Oxidoreductase;Phospholipid biosynthesis;Phospholipid metabolism

GO:0005829; GO:0005975; GO:0006650; GO:0008654; GO:0046167; GO:0046168; GO:0047952; GO:0051287

Inferred from homology

3

SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00394}.

null

PF07479;PF01210;

IPR008927;IPR013328;IPR006168;IPR006109;IPR011128;IPR036291;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

gpsA RT0429

false

Rickettsia typhi

164

row_251557

false

null

485,740

Q68WY7

MIIMRNYKFKLESLHQNQKVFRRCTVHSTVLHIISLHEDWSTRLTYKLSLYYCKIKNCYTTFKFEKSNRSIITRAERIINVQHLRRCKDIVDNFSGLISILLVLIFCINLSGCNTSKRLAYDNKYSYKELSKDDPHNLTYIGHYKVGKNYKIKGKIYKPYTPKYFTETGYASWYGGRKDGFHGKKTANGDRFNRNLLTAAHKTLPLPCLVKVTNKANNKSVILMVNDRGPFKKNRIIDVSQKAAEILAFKNQGITKVRIEYLPNETEKFLKKINLKKTENKIFANNYKESLFTKVTKNNQCSINCHIKLVNLKYKLAVNP

Endolytic peptidoglycan transglycosylase RlpA (EC 4.2.2.-)

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

320

37,374

Cell wall biogenesis/degradation;Lyase

GO:0000270; GO:0008932; GO:0071555

Inferred from homology

2

null

PF03330;

IPR034718;IPR009009;IPR036908;IPR022438;IPR012997;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

rlpA RT0378

false

Rickettsia typhi

165

row_466721

false

null

485,796

Q68XP6

MANLHQQQIIDKIQNITFKDGTFLNEVISDIIIKGNNIGFSIDISGKNKLEAEEIRLKAINELNNIKDVNNITIVFTQKKTIDKKAQKPKHFVENVKKIILVASGKGGVGKSTISALIAQQLSLENYQVGIVDADIYGPSIPHIFGINEIPKTVEGRIIPILAQNIQIISIGFFVKAHSAIIYRGPMASKIIYQLLSNTRWNNLDYLIIDMPPGTGDIHLSMLENYHLDGVIVVTTPQKISEIDVIRSIDLYRKLGLPILGIIENMIYMLESDRCGHLSKKYNIPLIAKIPIIPQIANACDKSLPLTNLLTLPLEKYL

Iron-sulfur cluster carrier protein

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

318

35,466

ATP-binding;Hydrolase;Iron;Iron-sulfur;Metal-binding;Nucleotide-binding

GO:0005524; GO:0016226; GO:0016887; GO:0046872; GO:0051539; GO:0140663

Inferred from homology

2

null

PF10609;

IPR000808;IPR019591;IPR044304;IPR027417;IPR033756;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

mrp RT0110

false

Rickettsia typhi

166

row_466777

false

null

555,562

Q68X33

MKQNTYSPLVSIIIPVYNGANYMREAIDSALAQTYKNIEIIVVNDGSKDKTETIALSYGDKICYFYKENGGCGSALNYGIKNMKGEYFSWLSHDDLYYPNKIEHQINILNKLDNKDVIVYCGYELIDQKSHSLYFVKPDQRYSKEKLDISLFPLLHSLIHGCTLLIPSILFKKIGLFDESLKYTHDYDLWFKFLRVSSVYFDHEVLIKSRVHDAQTTNTALNQLEEYEALWSGFLKKLTKQEMIMIKGSTHQFLSDIAVFFKKNGYIKSYQLALAMTDKKIIGGFCTFIIKEIIYSLRKYGINTTITKIYTWIRKNRK

Uncharacterized glycosyltransferase RT0329 (EC 2.4.-.-)

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

318

37,003

Glycosyltransferase;Transferase

GO:0009058; GO:0016758

Inferred from homology

1

null

PF00535;

IPR001173;IPR029044;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

RT0329

false

Rickettsia typhi

167

row_535573

false

null

266,758

Q68VX7

MTCKIIGSGGYLPQKIISNDELTKFVDTNDKWIRTRTGIFQRHIAGDTEYTSHLALKSAQKAIEDAMISVDDIDLIITCTTTPDNSFPSVATKLHGYLGLTNIPSFDLQAVCAGFIYGLQLTNSLIVSGKYKTILLIGAEKMTSLLDWNDRSTCVLFGDGAGSVILQRSNDESGLIDSNIFSSGTDYEILYTSGGTSMNGTSGKIVMQGQKLFRHAIAKMLQSIEDLLHANQFSVSDIDYFIPHQANIRIINKLAELLNIEEHKVVKTVEKHANCSAASIPLALSTLKESGKIKKGDILLFSAIGAGLTWGSALIRW

Beta-ketoacyl-[acyl-carrier-protein] synthase III (Beta-ketoacyl-ACP synthase III) (KAS III) (EC 2.3.1.180) (3-oxoacyl-[acyl-carrier-protein] synthase 3) (3-oxoacyl-[acyl-carrier-protein] synthase III)

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

317

34,553

Acyltransferase;Cytoplasm;Fatty acid biosynthesis;Fatty acid metabolism;Lipid biosynthesis;Lipid metabolism;Multifunctional enzyme;Transferase

GO:0004315; GO:0005737; GO:0006633; GO:0033818; GO:0044550

Inferred from homology

3

SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01815}.

null

PF08545;PF08541;

IPR013747;IPR013751;IPR004655;IPR016039;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

fabH RT0759

false

Rickettsia typhi

168

row_251512

false

null

485,745

Q68WZ8

MTKNPKISLIGSGNIGGTLAHLISLKKLGDIVLFDVAEGVPQGKALDIMQAATIAGADIKIKGTNNYKDIEGSDAVIITAGLPRKPGMSRDDLISVNTKIMQDVAQNIKKYARNAFVIVITNPLDIMVYVMLKESGLPHNKVIGMAGVLDSSRFNLFLAEEFKVSVRNVNSIVLGGHGDAMVPLVRYSTISGVPIPDLIKMGLSSNKNIEKIIDRTRNGGGEIVALLKTGSAYYAPAASAIAMLESYLKDKRQILTCAAYLQGEYDVHDLYIGVPIIIGKEGVIKVIELQLTEEEKILFDKSVVGVKKLIDAIQ

Malate dehydrogenase (EC 1.1.1.37)

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

314

33,833

NAD;Oxidoreductase;Tricarboxylic acid cycle

GO:0004459; GO:0006089; GO:0006099; GO:0030060

Inferred from homology

2

null

PF02866;PF00056;

IPR001557;IPR022383;IPR001236;IPR015955;IPR011275;IPR036291;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

mdh RT0365

false

Rickettsia typhi

169

row_466726

false

null

266,796

Q68WM5

MIKKEIIILCGPTASGKSYLGHELAKAYGCEIINIDSMQVYREIPIITASPIQIYNTGIHYHLYNFLSITEDFSVIKYLKLASEKIREITARGKIPILIGGTGLYINLLVFGYNNIPDISQDVRVQVRNLHNEIGNIELWNKLEKLDPIAATKINHCDTQRLIRAYEVLMHTGKSIFSFHTAQKERILSDFNFKIIFLNPERKFLYKTCDERLDKIFKDKAIDEIALIKKQFTPKEYANLKAVGIKEIIAYLDGNLTLNDALNVAQMRTRQYAKRQVTWFTHQIQDKTILEYSTQEEFEQILRNLLFTLKS

tRNA dimethylallyltransferase (EC 2.5.1.75) (Dimethylallyl diphosphate:tRNA dimethylallyltransferase) (DMAPP:tRNA dimethylallyltransferase) (DMATase) (Isopentenyl-diphosphate:tRNA isopentenyltransferase) (IPP transferase) (IPPT) (IPTase)

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

311

36,024

ATP-binding;Magnesium;Nucleotide-binding;Transferase;tRNA processing

GO:0005524; GO:0006400; GO:0052381

Inferred from homology

3

null

PF01715;

IPR039657;IPR018022;IPR027417;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

miaA RT0495

false

Rickettsia typhi

170

row_251549

false

null

485,731

Q68WT3

MKITTKVLIIGSGPAGLSAAIYTARSSLKPILINGMQPGGQLTMTTDVENYPGFAKTIQGPWLMEQMSIQAKNVGTEIINDYVERVDLSKRPFKIFTGTGNKYEADSIIICTGAESKWLGITSEQEFRGFGVSSCAICDGFFFKNQDIVVVGGGNSALEEALYLTNHANKVTVVHRRNSFRAEKILQDRLFKNPKISVIWDHVIDEIVGSNQPKTVTGVKIKNVYTNEINLVNCSGVFIAIGHTPNTTLFNGQIAIDDDNYIITQTGSTRTSVEGVFAAGDVQDKIYRQAITAAASGCMAALEVAKFLNK

Thioredoxin reductase (TRXR) (EC 1.8.1.9)

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

310

33,699

Cytoplasm;Disulfide bond;FAD;Flavoprotein;NADP;Oxidoreductase;Redox-active center

GO:0004791; GO:0005737; GO:0019430

Inferred from homology

2

SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.

null

PF07992;

IPR036188;IPR023753;IPR050097;IPR008255;IPR005982;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

trxB RT0432

false

Rickettsia typhi

171

row_466712

false

null

485,661

Q68W49

MIKLKSILNFLYNIANKDGFKGYKECRTSAYKNVFDDSSTKSTSKFHLGISDTKNLLSLQNIIGLILIIFAGVLFYAYILQHEWRYVTLSDAQVKRYRISEKKALSLYQLMKDTHELLTKNNIKYWIESGTLLGAVRHQGIIPFDDDLDIGIMHEDEIHFQQILPQFKQLGYRIKHNKIYVICGERCLDIFIFHKEKDKFVHILYDQYPNDFFYENELYPLKKYKFGNIEVYGPFDPIGNLNRQYPEWDKYAIIYSPHSFHLLFLSNIEKKTKFILTPELLKPAQPFGPLKDKVNIVNSANIYNDMDYH

Uncharacterized protein RT0683

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

309

36,466

Membrane;Transferase;Transmembrane;Transmembrane helix

GO:0009100; GO:0016020; GO:0016740

Inferred from homology

2

SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.

null

TRANSMEM 62..82; /note="Helical"; /evidence="ECO:0000255"

PF04991;

IPR007074;IPR052942;IPR005728;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

RT0683

false

Rickettsia typhi

172

row_466642

false

null

485,817

Q68XV6

MSEINISAAAVKELREKTGAGMMDCKKALIETSGNFEEAIDFLRKKGLAAAVKKFGRIASEGLTAIKINGLTSVVIEVNSETDFVARNEQFQNLVKDIVNLAIIAQNIDALKISKMQSGKSVEEEIIENIATIGENLTLRRMDILEISNGAIGSYVHNEVVPHLGKISVLVGLESNAKDKAKLAALAKQIAVHVAGNNPQSIDTLSLDQALVERERKVFFEKSKEEGKPDHIIEKMVEGRIRKFFSEVVLLQQNFLFEPKLTVAEVIKNAEQELGAEIKITKFIRYALGEGIEHEEKNFADEVASITKC

Elongation factor Ts (EF-Ts)

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

309

34,047

Cytoplasm;Elongation factor;Protein biosynthesis

GO:0003746; GO:0005737

Inferred from homology

2

SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00050}.

null

PF00889;

IPR036402;IPR001816;IPR014039;IPR018101;IPR009060;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

tsf RT0049

false

Rickettsia typhi

173

row_466798

false

null

485,830

Q68XY2

MQIYPLRFVPNKINFDFMNFKKVSYSFSIILSLISLIWIGIYKFNFGIDFVGGIVIEVRLDRAPDLPKMRAVLSALGIGEVVLQNFESEHDLSIRFGSSSEENLMKNIDIIKTSLRNNFPYNFEYRKVDFVGPQVGRHLIEAGAMAMLFSFLAIMVYIGVRFEWYFGFGILIALVHDVILALGFMSITKLDFNLSTIAAVLTIIGYSVNDSVVIYDRIRENLRKYHKKNITEIINLSINETLSRTILTVITTLLANLALILFGGKAIHSFSVLVFFGIIAGTYSSIFISAPILTIFANRKFNKKVIER

Protein translocase subunit SecF

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

308

34,940

Cell inner membrane;Cell membrane;Membrane;Protein transport;Translocation;Transmembrane;Transmembrane helix;Transport

GO:0005886; GO:0006605; GO:0015450; GO:0043952; GO:0065002

Inferred from homology

2

SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-Rule:MF_01464}; Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01464}.

null

TRANSMEM 23..42; /note="Helical"; /evidence="ECO:0000255|HAMAP-Rule:MF_01464"; TRANSMEM 140..160; /note="Helical"; /evidence="ECO:0000255|HAMAP-Rule:MF_01464"; TRANSMEM 164..184; /note="Helical"; /evidence="ECO:0000255|HAMAP-Rule:MF_01464"; TRANSMEM 194..214; /note="Helical"; /evidence="ECO:0000255|HAMAP-Rule:MF_01464"; TRANSMEM 246..266; /note="Helical"; /evidence="ECO:0000255|HAMAP-Rule:MF_01464"; TRANSMEM 272..292; /note="Helical"; /evidence="ECO:0000255|HAMAP-Rule:MF_01464"

PF07549;PF02355;

IPR022813;IPR022645;IPR022646;IPR048634;IPR055344;IPR005665;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

secF RT0022

false

Rickettsia typhi

174

row_466809

false

null

485,713

Q68WG7

MSQYHIPVMLSEVLEVLAPKGYESYLDCTFGAGGYSNAILKSCYCSVTSLDCDPHVIERVEQIKQDYGERFSFIKTNFADSFGKLKQQKFDGIVMDLGVSSMQLDIAGRGFSFLYDGPLDMRMSAQGFSAEEFVNTADEEEISDVIYKYGNESLSRRIAKNIIKYRKIARIDSTRKLAEIVRYSIGFRKGKIDSATKTFQAIRIYINNELGELERFLANVKNILKKNGRLVVVSFHSLEDRIVKNFFKENSAKPVARSKYAKDEIKIDQNKWLEIITHKVLTPSSQEIRLNVRARSAKLRAAKKIL

Ribosomal RNA small subunit methyltransferase H (EC 2.1.1.199) (16S rRNA m(4)C1402 methyltransferase) (rRNA (cytosine-N(4)-)-methyltransferase RsmH)

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

306

34,890

Cytoplasm;Methyltransferase;rRNA processing;S-adenosyl-L-methionine;Transferase

GO:0005737; GO:0070475; GO:0071424

Inferred from homology

2

SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01007}.

null

PF01795;

IPR002903;IPR023397;IPR029063;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

rsmH mraW RT0557

false

Rickettsia typhi

175

row_466694

false

null

485,639

Q68VT2

MLDISIQELIKQWQKYLILQRNYSNNTVIAYNNDLKHFLEFMNYYNSELVTINHIKTVDIRLIRSWLAKRKYENFTASSIARGLSTVKNFYKFLEKTILLNSHIIFSIKSPKKAKLLPKALSVDDVLISLEHIEGYGNVKWVELRNKALLVLIYAAGLRISEALSITKLHLQNLEFIKIIGKGSKERIIPWLPFARNLITKYLGILPYKLDENEPIFRGKHGKKLQPSVFNRELIKLKRVYGLPEYLTAHSFRHSFASHLLEYGADLRSIQELLGHKSLSTTQKYTQTSIKHLEAVYNTAYPIKK

Tyrosine recombinase XerC

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

305

35,490

Cell cycle;Cell division;Chromosome partition;Cytoplasm;DNA integration;DNA recombination;DNA-binding

GO:0003677; GO:0005737; GO:0006313; GO:0007059; GO:0009037; GO:0051301

Inferred from homology

2

SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01808}.

null

PF02899;PF00589;

IPR044068;IPR011010;IPR013762;IPR002104;IPR010998;IPR004107;IPR023009;IPR050090;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

xerC RT0805

false

Rickettsia typhi

176

row_466621

false

null

266,757

Q68VX4

MITIFNKLKQSLSKTSNTISTGIDKIFYKKKLDQTTLNELEELLISSDISITVVTHIIEKFKNVKFDKTIDSDTVKEAIAKLIEQQLSKSEIPFTLSENKLNIILICGVNGVGKTTTIGKLSALYSAQGKKVAVAACDTFRAAAINQLSSWVDRANALLITGEVSADPASVAYRAIQESIKQNIDILFIDTAGRLHNNKNLMDELSKIVKVIKKLDENAPTHSILIIDAVTGQNTYNQIEYFNDVTNLTGLIITKLDGSAKAGVLVGAVQKFNLPIYFIGIGEQIEDLKIFNRHDFSRSLVGL

Signal recognition particle receptor FtsY (SRP receptor) (EC 3.6.5.4)

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

303

33,334

Cell inner membrane;Cell membrane;Cytoplasm;GTP-binding;Hydrolase;Membrane;Nucleotide-binding;Receptor

GO:0003924; GO:0005047; GO:0005525; GO:0005737; GO:0005886; GO:0006614; GO:0016887

Inferred from homology

3

SUBCELLULAR LOCATION: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00920}.

null

PF00448;PF02881;

IPR003593;IPR027417;IPR013822;IPR004390;IPR036225;IPR000897;IPR042101;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

ftsY RT0762

false

Rickettsia typhi

177

row_251511

false

null

404,762

O33582

MKVIFMGTPEFAVPTLKKLIIHHEVKAVFTQQPKAKGRGLYLAKSPIHQLAFEHQIPVYSPSTLRNDETINLINKVDADIIVVIAYGFIVPKAILEAKKYGCLNIHPSDLPRHRGAAPLQRTIIEGDLKSSVCIMRMDSGLDTGDILLKEDLNLEKRITLDELSNRCAHLGAELLIQTLANIDNIVPVKQSSNGVTYAHKLTKAEGKINWYESAYSIDCKIRGMNPWPGAYFSYNDKIIKILEAEYLNYNHHFIPGTVISNKLEIACGSGILRVTKLQQESKKALNIEAFLRGTNILKDTILK

Methionyl-tRNA formyltransferase (EC 2.1.2.9)

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

303

33,913

Protein biosynthesis;Transferase

GO:0004479; GO:0005829

Inferred from homology

2

null

PF02911;PF00551;

IPR005794;IPR005793;IPR002376;IPR036477;IPR011034;IPR044135;IPR041711;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

fmt RT0198

false

Rickettsia typhi

178

row_387289

false

null

485,762

Q68XB2

MIIDVNTPIPFRLDKYLKRLYPSLTQGVIEKALRQKQVTVNFQKAEANLRVKEGDTIFINDYFNLPVTQHETLVFADAEIKLAKKILTDYLIYEDDHLIAINKPASLATQGGSKINLSIDSALKYLNYQGADFKLVHRLDKETSGLLLIAKNYLSSVKLHDAFKEKLVIKKYFAITYGRPVKNVGIVKSNIGKSKGRMFKITDIDSDNGKLAITYYKLLKSLNNNLFLIEFMPVTGRMHQLRLHAQLLGCPILGDDKYGNKEVMPYSKYMFLHANNIYLSESIVGKEIKLEAKLPFYFTRRLT

Ribosomal large subunit pseudouridine synthase C (EC 5.4.99.24) (23S rRNA pseudouridine(955/2504/2580) synthase) (rRNA pseudouridylate synthase C) (rRNA-uridine isomerase C)

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

303

34,662

Isomerase;RNA-binding;rRNA processing

GO:0000455; GO:0003723; GO:0160141

Inferred from homology

2

null

PF00849;PF01479;

IPR020103;IPR006224;IPR006145;IPR050188;IPR002942;IPR036986;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

rluC RT0249

false

Rickettsia typhi

179

row_466743

false

null

555,551

Q68VW2

MSWIIFYTIIAALLILDLGIVHKKNTVIAFKSSVFLSLFYFIISCLFGIYIYHNMGLDHAREYYTCFLIEKAMALDNIFIISIIFQFFKIPTTYQHRVLFFGIIGVIIFKAIIIYGGIMLIHKFSWLLYIFAVILIATGIKTFNVSHKTYDIQNSYIYKSIIKNLNITHNLEGHKFVIKRNNKLYFSPLFVSLILIETIDVVFAIDSIAAIFAITNDVYIIYTSNIFAILGLRSLFFCLSEIVERFSYIKYSLALILIFIGFKIFMHHYIAIPAYISLTVTITSLLLGIIASIMRKNMIDHK

Uncharacterized membrane protein RT0774

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

302

34,928

Cell membrane;Membrane;Transmembrane;Transmembrane helix

GO:0005886

Inferred from homology

1

SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.

null

TRANSMEM 1..21; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 32..52; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 67..87; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 98..118; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 120..140; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 194..214; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 218..238; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 253..273; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 274..294; /note="Helical"; /evidence="ECO:0000255"

PF03741;

IPR005496;IPR022369;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

RT0774

false

Rickettsia typhi

180

row_535562

false

null

266,800

Q68WR3

MINSIRIGTRNSTLALIQTNLVIAQIKQFFPDINCEIVPIITSGDLIQNKPLYDIGGKALFLKEIEQALLDKKIDLAVHSLKDIPGRIPVDLVIAAVLEREDPRDVLVCLNYKSIETLPQNAVIGSSAVRRKAFIKKIRPDLNIKVFRGNVDSRIKKLMTGEVDATILSYAGLKRLNAFNKKYCHLIEYSQILPCVGQGVIAVEIRKDDNAMFNICNQINHIPTFELIKPERAFLEHLDANCSTPIGAYSQYLDAYNIQTDFMLGKLDCNKIIFQTEITNINTSRECGIKAAKMMLAQQ

Porphobilinogen deaminase (PBG) (EC 2.5.1.61) (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase)

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

299

33,561

Porphyrin biosynthesis;Transferase

GO:0004418; GO:0005737; GO:0006782

Inferred from homology

3

null

PF01379;PF03900;

IPR000860;IPR022419;IPR022417;IPR022418;IPR036803;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

hemC RT0453

false

Rickettsia typhi

181

row_251553

false

null

266,766

Q68W08

MTNVNRRPDWIKVKAPNSAEYYNTKDLIKNLRLNTVCEEAACPNIGECWSRKHATVMILGSVCTRACRFCNVKTGRPDLLDPHEPRRLAEAVQKLNLNHVVITSVDRDDLEDGGASHFAECINEIRRSSPNTTIEILTPDFLRKAGAVEVIANSKPDVFNHNVETVPSLYKTIRPGARYYNSLSLLHNIKKLSPEIFTKSGMMVGLGEEINEVVQVMDDLREANVDFLTIGQYLQPTKSHAEVIKYVTPEEFKYLERIAKTKGFLMVSATPLTRSSYHADKDFQKLKENYNIRLASM

Lipoyl synthase (EC 2.8.1.8) (Lip-syn) (LS) (Lipoate synthase) (Lipoic acid synthase) (Sulfur insertion protein LipA)

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

297

33,658

4Fe-4S;Cytoplasm;Iron;Iron-sulfur;Metal-binding;S-adenosyl-L-methionine;Transferase

GO:0005737; GO:0016992; GO:0046872; GO:0051539

Inferred from homology

3

SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00206}.

null

PF16881;PF04055;

IPR013785;IPR006638;IPR031691;IPR003698;IPR007197;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

lipA RT0727

false

Rickettsia typhi

182

row_251520

false

null

266,831

Q68XC1

MSILPIIKGEYKKDYNLKHLTWFKVGGNAEIFFKPFDSADLKSFLIQNNKKLPITTFGSGSNIIIRDGGIEGVVIKLGKNFNNIEFLDNHLIVGSSCLNYNLAKFCQANAISGFEFLVGIPGTIGGGVVMNAGAYGSAFQDIIVQIEALDFLGNFLTFTNKEIGFKYRGNNLPKDLILLKAIFKANKGDSQNILLKMNKINTTRSSTQPIKERTGGSTFKNPVGCKSWELIDKAGLRGYRIGGASMSELHCNFMINNGNATAKDLEDLGNFVRQKVFEDSGVELNWEIKRIGKYV

UDP-N-acetylenolpyruvoylglucosamine reductase (EC 1.3.1.98) (UDP-N-acetylmuramate dehydrogenase)

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

295

32,585

Cell cycle;Cell division;Cell shape;Cell wall biogenesis/degradation;Cytoplasm;FAD;Flavoprotein;NADP;Oxidoreductase;Peptidoglycan synthesis

GO:0005829; GO:0008360; GO:0008762; GO:0009252; GO:0051301; GO:0071555; GO:0071949

Inferred from homology

3

SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00037}.

null

PF01565;PF02873;

IPR016166;IPR036318;IPR016167;IPR016169;IPR003170;IPR011601;IPR036635;IPR006094;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

murB RT0240

false

Rickettsia typhi

183

row_251584

false

null

266,869

Q68XY6

MINQIQKTISVCIIGRPNSGKSTLLNRIIGEKLSIVTPKVQTTRSIITGIITLKDTQIILYDTPGIFEPKGMLEKAMVRCAWSSLYSADLVLSIIDSLKPLDDMAHNILNQFCLLNIVPIFLLNKIDIESKYLNDIKAFLKISHPKSLLFPISALCGKNVDVLLKYIKSKAKVSPWLYADDDITNLPMRFIAAEITREQLFLNLQQELPYKLTVQTEKFEELKDKSIKINQVIVISRESYKAIILGKNGTKIKDIGVKSRIQMEQLFCVPVHLFLFVKVHALWENKQEFYQYMKI

GTPase Era

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

295

33,745

Cell inner membrane;Cell membrane;Cytoplasm;GTP-binding;Membrane;Nucleotide-binding;Ribosome biogenesis;RNA-binding;rRNA-binding

GO:0000028; GO:0003924; GO:0005525; GO:0005829; GO:0005886; GO:0043024; GO:0070181

Inferred from homology

3

SUBCELLULAR LOCATION: Cytoplasm. Cell inner membrane {ECO:0000255|HAMAP-Rule:MF_00367}; Peripheral membrane protein {ECO:0000255|HAMAP-Rule:MF_00367}.

null

PF07650;PF01926;

IPR030388;IPR006073;IPR005662;IPR015946;IPR004044;IPR009019;IPR027417;IPR005225;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

era RT0018

false

Rickettsia typhi

184

row_251621

false

null

485,816

Q68XV5

MSKISPINIKELLDAGVHFGHKTSRWNPKMASYIYGERDDVHIIDLRQSAALMSVALNAIYETVKKDGKILFVSTKIQASDIIAEYAEKCGQYYVNNRWLGGMLTNWKTIACSIEKLEKLEKTLESEETRVCYTKKEILDMSRKKDKLLLSLAGIRNLNSKPDLLVVIDTNKEHIAINEAVKLNIPIVAVVDTNSNPDNINYPIPGNDDSIRSIRLYCSLFADAALQGLEESMKVSGVDIGTMQEHTDKALTSKTISKLKQTKKFSKTQNIDEETNTEFDQALSDACENKNSDNT

Small ribosomal subunit protein uS2 (30S ribosomal protein S2)

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

295

33,096

Ribonucleoprotein;Ribosomal protein

GO:0003735; GO:0006412; GO:0022627

Inferred from homology

2

null

PF00318;

IPR001865;IPR005706;IPR018130;IPR023591;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

rpsB RT0050

false

Rickettsia typhi

185

row_466797

false

null

555,553

Q68W65

MHKLLLIITVFSTFNVAQASLTSIVASVNDKPITFNEFHARKKMIMVLNNVENLTSDQDKQLSDLAINSLIDESLLFQYAGDREIQQDEIDNAIKSIEDRNKMPHGSLLQYLKNKSVNPESFIFQIKSELIKMNILSSLSRSVQVSNKEIDVAILSSDQKDVEILMQVFRSKDGSNKAFTKMNYLKNRLKKCSDVKKTLYDKFATMQLITSKLSKLGGVKQTIVKDLIPDKASNVFEVNNKFEIILVCSKKILNVTVDENNYVVNFLTNKKISQKAQKIFKNMRKKAAITIMFPS

Uncharacterized protein RT0667

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

295

33,568

Signal

null

Inferred from homology

1

null

SIGNAL 1..19; /evidence="ECO:0000255"

null

PF13624;

IPR050280;IPR027304;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

RT0667

false

Rickettsia typhi

186

row_535564

false

null

555,563

Q68X76

MFRKFLFIPLLIVTSLVKAEIIEVDSLSKITQDFKVNYNKNYLPQDLLVVTVLDKFLFKPFGIPIGEYIDQRRYLELAPLFSQINKNSKIIYIAQLILTNDSYKKELQESDFPSFVNEISNSQIPIIAVNNGFTGNFNNIPKFEIWFADYLKKNFYIDFSKSFPNNNYIIFNNLDSFANTYPVFYKGILTSNNISVAQVILNFLIQINFIPKCFILISSNRELIRSMEFQLNNHSSNILFIGYHYNNKTISAHKDIVYYTKMINDLIPQINKLKRNNPPLKNNNAKSKNSYETHK

Uncharacterized protein RT0286

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

295

34,469

Signal

null

Inferred from homology

1

null

SIGNAL 1..19; /evidence="ECO:0000255"

null

PF11019;

IPR022565;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

RT0286

false

Rickettsia typhi

187

row_535574

false

null

266,825

Q68X70

MHNTTKRVTVPALEAMLYETIKVLDHGFIRVIDYMGDDSSIVQAARVSYGKGTKQLNQDKGLINYLLRHYHTTPFEMCDIKFHIKLPIFIARQWIRHRTASVNEYSARYSILGNEFYLPEPTDIASQSAINKQCRAGDSLPKKVSEKVLAILEEDARRCYMHYKELMNADEDGNIIDENVAGIARELARMNLTLNYYTEWYWKINLHNLLHFLRLRTDSKAQYEIRVYAGKILDIVKAWVPFTYEAFEEYRLQGANISRKGLEVIKRMIQGEKVIHETSGMNKREWEELVKIFR

Flavin-dependent thymidylate synthase (FDTS) (EC 2.1.1.148) (FAD-dependent thymidylate synthase) (Thymidylate synthase ThyX) (TS) (TSase)

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

294

34,445

FAD;Flavoprotein;Methyltransferase;NADP;Nucleotide biosynthesis;Transferase

GO:0004799; GO:0006231; GO:0006235; GO:0032259; GO:0050660; GO:0050797; GO:0070402

Inferred from homology

3

null

PF02511;

IPR003669;IPR036098;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

thyX RT0292

false

Rickettsia typhi

188

row_251578

false

null

266,861

Q68XV0

MNDALKTYLKGICWFLLSLVTSSVNDVISKYLGTRLHSFEVAFFRFLFSSIVLLPFVVYYGKSTLKTRHPVIHVLRGLLLFFGMTSWTYGLTIAPVTTATVISFSIPLFTLILAVFILNENIIWQRWVVTVVGFIGLVVMLKPHTKDFNPEILYLILAAISFAMLDIINKKFVVKESMLSMLFYSAIVTAIVSLPVSMEYWITPSSFELTLLFVLGSSGSFILFFLLKAFTMVDATATAPYRYLELVISAIAAYFIFNEFPDKSTAHGAVIIIPATLFIMYSEKKSMSSKHESQ

S-adenosylmethionine uptake transporter

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

294

33,141

Amino-acid transport;Cell inner membrane;Cell membrane;Membrane;Repeat;Transmembrane;Transmembrane helix;Transport

GO:0005886; GO:0006865

Inferred from homology

3

SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.

null

TRANSMEM 8..28; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 41..61; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 72..91; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 98..118; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 121..141; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 148..168; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 178..198; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 207..227; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 237..257; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 260..280; /note="Helical"; /evidence="ECO:0000255"

PF00892;

IPR000620;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

sam RT0056

false

Rickettsia typhi

189

row_251613

false

null

302,887

Q9AKE4

MYNIFKGLITALITPFKNNKLDLYAFESILNQQIKHEVDAVLIAGSTGEANSLSFEEYKLLLKTSVEIVNNRMPIISGCSSNNTAYAIELAIASKKIGVDGFMASPPSYVKPTQHGIYKHFEALHEACNLPIMLYSAPTRSGVDFSDETILRLSKLPRILALKDCGVDLERPMRIRAIVKEDFNILTGNDEVVLAFHAQGVIGWISVTSNIAPKICKELLDKWYNNDIQGALEMHQKLLPLYKALFLESNPIPVKYAAHYLGLCENEIRLPLTEASDSAKKQIKKIITSLSIKI

4-hydroxy-tetrahydrodipicolinate synthase (HTPA synthase) (EC 4.3.3.7)

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

294

32,766

Amino-acid biosynthesis;Cytoplasm;Diaminopimelate biosynthesis;Lyase;Lysine biosynthesis;Schiff base

GO:0005737; GO:0008700; GO:0008840; GO:0009089; GO:0009436; GO:0019877

Inferred from homology

3

SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00418}.

null

PF00701;

IPR013785;IPR005263;IPR002220;IPR020625;IPR020624;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

dapA RT0415

false

Rickettsia typhi

190

row_286686

false

null

302,886

Q9AKE1

MAILINKKTKVICQGFTGSQGTFHSEQAIAYGTNMVGGVTPGKGGHTHLNLPVYNTVHEAKAKTDANASVIYVPPGFAADSILEAIDAKIEVVVCITEGIPVLDMVKVKRALIGSKTRLIGPNCPGVITPGECKIGIMPGHIHKTGIIGIVSRSGTLTYEAVAQTTAVGLGQSTCIGIGGDPVNGTSFVECIEMFLQDDETKAIIMIGEIGGNAEEDAADFIKQSKIKKPIVSFIAGITAPSDKRMGHAGAIISGGKGSAKDKLEALQSAGVTITKSPADIGKTMLDLLNKI

Succinate--CoA ligase [ADP-forming] subunit alpha (EC 6.2.1.5) (Succinyl-CoA synthetase subunit alpha) (SCS-alpha)

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

292

30,250

Ligase;Nucleotide-binding;Tricarboxylic acid cycle

GO:0000166; GO:0004775; GO:0004776; GO:0006099; GO:0009361

Inferred from homology

3

null

PF02629;PF00549;

IPR017440;IPR033847;IPR003781;IPR005810;IPR036291;IPR005811;IPR016102;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

sucD RT0419

false

Rickettsia typhi

191

row_286685

false

null

485,726

Q68WN3

MSNYWLNFYKPKGISSAKLVNIVKKIIGKTKIGHAGTLDVEAEGILPLAVGEATKLIQLLIDAKKTYIFSVKFGAQTDNGDYTGKVIASKNYIPSQEEAYAVCSKFIGNIKQIPPMFSAIKVNGIRAYKLAREGKVVELKPRNVTIYDLKCLNFDKEKAIATYYTECSKGTYIRTLTEDLALSLQSLGFVIELRRTQVGIFKEENAIHIKASDAITKNFIDKKSIKIEAILDDILVLDATDDQAQKIKYGQKCVFDYEEDVNFLWVRYNGTLLAIGSLNKSCFNSLRVFNLL

tRNA pseudouridine synthase B (EC 5.4.99.25) (tRNA pseudouridine(55) synthase) (Psi55 synthase) (tRNA pseudouridylate synthase) (tRNA-uridine isomerase)

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

292

32,722

Isomerase;tRNA processing

GO:0003723; GO:0031119; GO:0160148; GO:1990481

Inferred from homology

2

null

PF16198;PF01509;

IPR020103;IPR002501;IPR014780;IPR032819;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

truB RT0487

false

Rickettsia typhi

192

row_466707

false

null

555,565

Q68XF1

MKKISTFIITKNEEARIARAINSVKNITDEVIVVDNESTDDTVHIAKTLGAKVIVKPWLGYVGQKSFAESMCVNDWVLNIDADEELSQELQDEIEYIFASHNQDRYLAYQIKLLIMYRGDQKSRMFAPLNKCIRLYNKKFASFANTINSTTHDSVVFNKDVDFIGKIYLLNGIAYHYSGTSIEQLVNKANFYSSEQAKDLVKQGKKFSNFRLATEMIWWFLKAFFIRRYFVFGFDGFVDSIIFAFARFLRLAKLRELSLKSRNVIASDNYINYCMDIKSLLQKKKRSRYPKK

Uncharacterized glycosyltransferase RT0209 (EC 2.4.-.-)

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

292

33,996

Glycosyltransferase;Transferase

GO:0016757

Inferred from homology

1

null

PF00535;

IPR001173;IPR029044;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

RT0209

false

Rickettsia typhi

193

row_535576

false

null

266,829

Q68XB5

MQQSTLLKPVSCYGIGVHTGKRTQLTIEPAKENTGIIFIRTDISSENNYIEASYYNVSDTLLSTTISNNHKIQVSTIEHLMAALWGCSIDNAVIKIDGPEVPIMDGSSKPFVFMIECAGKKLQNAPKKYLKILKEIKVVNKDCELYCTPSEHITVDLTIDFSSKAIGKQNLNFGVQESFTKNIADARTFGFIKDVEYLKSKGLAQGASFENAIGIDEHDKVLNPSGLRYADEFVRHKLLDLFGDLYTSGISIVSAIKGYKTSHAFNNELLHKIFSDTTSYKFVTSNELS

UDP-3-O-acyl-N-acetylglucosamine deacetylase (UDP-3-O-acyl-GlcNAc deacetylase) (EC 3.5.1.108) (UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase)

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

289

32,097

Hydrolase;Lipid A biosynthesis;Lipid biosynthesis;Lipid metabolism;Metal-binding;Zinc

GO:0009245; GO:0016020; GO:0046872; GO:0103117

Inferred from homology

3

null

PF03331;

IPR020568;IPR004463;IPR011334;IPR015870;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

lpxC RT0246

false

Rickettsia typhi

194

row_251582

false

null

485,637

Q68VR3

MKKLSFQQIILILQNYWQDYGCAILQPYDAHVGAGTFHPATVLRCLGTKPWFVAYVQPSRRPCDSRYGMHPNRMQHYYQFQVILKPSPDNIQDLYLKSLECLNLDLKTHDIRFVEDDWESPTLGASGLGWEVWCDGMEVSQFTYMQQVGGIECYPVACEITYGLERLALYIQGIDEVKELDWNGQIGEKALKYGEVDFEAERQFSKYNLEFADSEMLLRHFKDSGEQCERLVNVNLPMPAYDECLKASHYFNQLNALGVISVTERASYILRVRYLAKICCIKWLELSSE

Glycine--tRNA ligase alpha subunit (EC 6.1.1.14) (Glycyl-tRNA synthetase alpha subunit) (GlyRS)

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

289

33,493

Aminoacyl-tRNA synthetase;ATP-binding;Cytoplasm;Ligase;Nucleotide-binding;Protein biosynthesis

GO:0004820; GO:0005524; GO:0005829; GO:0006426

Inferred from homology

2

SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00254}.

null

PF02091;

IPR045864;IPR006194;IPR002310;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

glyQ RT0839

false

Rickettsia typhi

195

row_466619

false

null

302,888

Q9AKE5

MIKLEQICRYVWINGDLIPYQFARIHVLTHSLHYSGSVFEGERAYNGKVFKLKEHTERLIQSAEALGLKVPYSVDEIIKAHEFLITHNNIKDAYIRPLIWCGDESLNITNPALSTNFLIASIPSMPMSCEQGVNLHVSRWRKAMPDSTPVQSKSAAQYNMAITSKKEAKALGYDDALLLDYEGFIAECTTTNIFFVKDTTLYTPIADRFLNGITRKTIIEIAKNLCLEVKEERLKLAQIEYFTGCFVTGTAIEVQNISSIDLGDKKILFEDCKIADLLKKEYLRIVRG

Probable branched-chain-amino-acid aminotransferase (BCAT) (EC 2.6.1.42)

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

288

32,694

Amino-acid biosynthesis;Aminotransferase;Branched-chain amino acid biosynthesis;Pyridoxal phosphate;Transferase

GO:0005829; GO:0009097; GO:0009098; GO:0009099; GO:0052654; GO:0052655; GO:0052656

Inferred from homology

3

null

PF01063;

IPR001544;IPR018300;IPR036038;IPR043132;IPR043131;IPR033939;IPR050571;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

ilvE RT0414

false

Rickettsia typhi

196

row_286687

false

null

485,643

Q68VU7

MSNLKQLRTRIKSVKSTQKITKAMQLVSASKMTKIKTQIANSNFYIEAINKMMSNIFSMTLCELSIEEQKFFNTMPSKANLLIVMTSERGLCGMFNYSIIKQVKNDIKELANKGEQIKLIIIGKKGYEVLKRQYANYIDSYFEFPKSHYANLILQLKEKIMYAVENLEISNCIIYFNKFKNAMTQILTKQKILPIEKHRDYSVVENYHFEYEGKNLISNLINLYLYAKINYALLQNIVSEEGARMTAMDSATNNANDLISKLVLKLNRSRQTIITTELIEIIAGAEAV

ATP synthase gamma chain (ATP synthase F1 sector gamma subunit) (F-ATPase gamma subunit)

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

288

33,169

ATP synthesis;Cell inner membrane;Cell membrane;CF(1);Hydrogen ion transport;Ion transport;Membrane;Transport

GO:0005524; GO:0005886; GO:0042777; GO:0045259; GO:0046933

Inferred from homology

2

SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-Rule:MF_00815}; Peripheral membrane protein {ECO:0000255|HAMAP-Rule:MF_00815}.

null

PF00231;

IPR035968;IPR000131;IPR023632;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

atpG RT0789

false

Rickettsia typhi

197

row_466625

false

null

485,811

Q68XT3

MVKNKGLGRGLSSLLGEEVLPIKSEIVQIINIDKIKPNENQPRKHFEYNKIKELADSILNNGLLQPIIVDNNFQIIAGERRWRACKLAQVLEIPVIIKNFDTRESMETALIENIQRTDLTVMEEARGFKYLVDNFNYTVEKLAERLGKSRSHIANLLRLNNLPQSIQDKLNENILSMGHARCLINHEYAEEIANHIINHDLNVRQTEALVRQWHKNEYKKSTNNTNKVGKLCFKDNIIDNDLELLVKALSKKFGIKITIDNCNLGGKLMFHYKDLEELDLILSKLN

Probable chromosome-partitioning protein ParB

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

286

32,962

Chromosome partition;DNA-binding

GO:0003677; GO:0005694; GO:0007059; GO:0045881

Inferred from homology

2

null

PF17762;PF23552;PF02195;

IPR050336;IPR041468;IPR004437;IPR003115;IPR036086;IPR057240;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

parB RT0073

false

Rickettsia typhi

198

row_466792

false

null

266,795

Q68WL9

MNNIIDGKALANEILADLKLEIQGFKEKTQTSPKLAIVLVGDNPASMIYIKNKIKNAQQVGIDTLLVNLSTNIYTDDLISKINELNLDKEISGIIVQLPLPSSIDENKILSAVLPSKDSDGFHPLNVGYLHSGINQGFIPCTALGCLAVIKKYAPNLNGKDAVIVGRSNIVGKPLSALLLKENCSVTICHSKTCNLSSITSKADIVVVAIGSPLKLTAEYFNPESIVIDVGINRISNNKIIGDVDFENVKSKVKYITPVPGGIGPMTIAFLLKNTVKAFKNAIAL

Bifunctional protein FolD [Includes: Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)]

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

257,363

285

30,547

Amino-acid biosynthesis;Histidine biosynthesis;Hydrolase;Methionine biosynthesis;Multifunctional enzyme;NADP;One-carbon metabolism;Oxidoreductase;Purine biosynthesis

GO:0000105; GO:0004477; GO:0004488; GO:0005829; GO:0006164; GO:0009086; GO:0035999

Inferred from homology

3

null

PF00763;PF02882;

IPR046346;IPR036291;IPR000672;IPR020630;IPR020867;IPR020631;

null

cellular organisms (no rank), Bacteria (domain), Pseudomonadati (kingdom), Pseudomonadota (phylum), Alphaproteobacteria (class), Rickettsiales (order), Rickettsiaceae (family), Rickettsieae (tribe), Rickettsia (genus), typhus group (no rank), Rickettsia typhi (species)

folD RT0501

false

Rickettsia typhi

199

row_251548

false

null