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ThermoFisherScientific
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Cat#A10037;
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|
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Quercetinhydrate TCI Cat#P0042
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L-Ascorbicacid Sigma Cat#A4544-500G
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4%paraformaldehyde,PFA Dingguo,China Cat#AR-0211
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TritonX-100 Sigma-Aldrich Cat#T9284
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RNaseInhibitor ThermoFisherScientific Cat#AM2694
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Promega
| null |
Superasin
|
Cat#N2615
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null | null | null | null | null | null | null | null | null |
ggplot2(version:3.2.1) Wickhametal.,2016
|
https://ggplot2.tidyverse.org/
|
null | null | null | null | null | null | null | null | null |
GENIE3(version:1.6.0) Huynh-Thuetal.,2010
|
https://bioconductor.org/packages/release/bioc/html/
GENIE3.html
|
null | null | null | null | null | null | null | null | null |
Cytoscape(version:3.7.1) Shannonetal.,2003
|
https://cytoscape.org/
|
null | null | null | null | null | null | null | null | null |
CellPhoneDB(version:1.1.0) Vento-Tormoetal.,2018
|
https://github.com/Teichlab/cellphonedb
|
null | null | null | null | null | null | null | null | null |
HISAT2(version:2.1.0) Kimetal.,2015
|
https://ccb.jhu.edu/software/hisat2/index.shtml
|
null | null | null | null | null | null | null | null | null |
RcisTarget(version:1.4.0) Aibaretal.,2017
|
https://bioconductor.org/packages/release/bioc/
html/RcisTarget.html
|
null | null | null |
Loveetal.,2014
| null | null | null | null |
DESeq2(version:1.2.4)
|
https://bioconductor.org/packages/release/bioc/
html/DESeq2.html
|
A Single-Cell Transcriptomic Atlas of Human Skin Aging
This dataset contains structured tables extracted from the supplementary materials of the publication:
"A single-cell transcriptomic atlas of human skin aging"
Cell Reports, 2020
DOI: 10.1016/j.celrep.2020.108132
The data has been processed from the publication PDF into a .parquet file to facilitate downstream analysis and integration into machine learning workflows.
📦 Dataset Description
The dataset includes multiple tables capturing aging-related transcriptomic changes in human skin tissue at the single-cell level. Tables were extracted using PDF parsing tools and contain gene expression summaries and annotations useful for skin biology and aging research.
🔧 Usage Instructions
To load the Parquet file in Python:
import pandas as pd
df = pd.read_parquet("skin_aging_data.parquet")
print(df.head())
🚀 Use Cases
- Aging biomarker discovery in dermal and epidermal compartments
- Training skin-specific biological age predictors
- Integrating skin aging profiles with other tissue atlases
- Cross-species comparison of skin aging signatures
- Evaluation of anti-aging interventions at single-cell resolution
📖 Citation
If you use this dataset, please cite:
Xie, W., et al. A single-cell transcriptomic atlas of human skin aging. Cell Reports, 2020.
DOI: 10.1016/j.celrep.2020.108132
🙏 Acknowledgments
This dataset was curated and converted by Iris Lee for open access machine learning research in aging biology and skin regeneration.
Source publication by Xie et al. (2020) — Cell Reports.
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