32 14 71 15 COMPOUND PHYSICAL PARAMETERS
12 17 21 18 LRC FILE NUMBER
66 17 73 18 LOT NUMBER
22 18 26 19 B164
12 19 20 20 PHYSICAL STATE
22 21 44 22 Brownish- gray powder
13 22 14 23 pH
17 26 86 32 The pH of a 50% concentration of B164 in water was calculated to be 4.82 at 25°C according to the extrapolation procedures by Dr. P. D. Schickedantz, Lorillard Research Center Accession Number 1662.
13 37 18 37 SOLUBILITY
20 37 57 39 (See SOP FOX Biological Solutions)
15 39 18 40 ORAL
29 40 37 42 BC20- 48
17 40 28 42 Reference:
17 43 74 47 B164 forms a suspension in corn oil at 0.5g/ 1.5 ml Triple dosing is required
15 50 27 51 ACUTE CADCOVASCULAR
17 51 90 54 (See SOP for Determination of Solubility of Materials for Acute Cardiovascular and Respiratory Effects Study Beagle Dogs)
17 55 29 57 Reference:
29 55 37 57 BC20- 48
17 58 67 60 B164 is insoluble according to this procedure
12 66 27 67 STORAGE RECOMMENDATIONS
17 67 77 69 Refrigerate in amber glass bottle at no more than 8°C
84 70 86 79 00865872
12 77 24 77 COMPOUND SENSITIVE TO
15 79 18 80 [] Air
20 79 24 80 [] HEAT
34 79 39 80 [] OTHER
26 79 32 80 [] MOISTURE
12 82 16 83 SAFETY
16 82 22 83 COMMENTS
22 82 28 83 (SUGGESTED
27 82 33 83 HANDLING
33 82 39 83 PROCEDURE
12 92 18 92 SIGNATURE:
17 92 41 94 
66 92 68 93 DATE
70 92 82 94 8/22/83
12 94 26 95 LORILLARD RESEARCH CENTER
85 94 92 96 FORM 1921
