question: Why do dry/chapped skin ache after mosturizing?
comment: Nerves are more sensitive when they are moist/warm. Same way you can't taste anything if your tongue is dry and can feel temperature much more if your hands are wet. Once you moisturise your hands the nerves become more sensitive to temperature and touch. Which can ache if the skin condition is bad enough and has caused sensitive skin in that area.
passages: Section::::Determining accuracy.:Measurements.
   Butternut squash and Acorn squash have been known to cause an allergic reaction in many individuals, especially in food preparation where the squash skin is cut and exposed to the epidermis. Food handlers and kitchen workers often take precautions to wear rubber or latex gloves when peeling butternut and acorn squash to avoid temporary Butternut squash (Cucurbita moschata) dermatitis
  
  A contact dermatitis reaction to butternut or acorn squash may result in orange and cracked skin, a sensation of "tightness", "roughness" or "rawness".
   Section::::Industry.
  
  Patlur residents are employed in primary and secondary industries, particularly the growing and processing of groundnut (peanut) into oil in mills.
  
  Section::::Kariyakali Amman festival.
   Maceration also occurs during treatment of wounds because the skin under the bandage becomes wet due to perspiration, urine or other bodily fluids. The excess moisture is sometimes called hyperhydration.
  
  Wrinkles are the first sign that the skin is over-hydrated. In addition, macerated skin becomes extremely soft and takes on a whitish appearance. However, this white skin should not be confused with the pale, whitish appearance of the new epithelial tissue in a healing wound.
   Section::::Tyrosine sulfation.
   Side effects may include irritation of the skin and discoloration of clothing. A harsh burn on a child from an undissolved tablet has been reported. For treating eczema, it is recommended using for a few days at a time due to the possibility of it irritating the skin. Higher concentration solutions can result in chemical burns. Therefore, the British National Formulary recommends 100 mg be dissolved in a liter of water before use to form a 1:10,000 (0.01%) solution. Wrapping the dressings soaked with potassium permanganate is not recommended.
  
  Section::::Side effects.:By mouth.
   Adverse effects for topical use are generally mild and include, erythema, pruritis, dermatitis, rash, edema or inflammation.
  
  Section::::Contraindications.
  
  People with chronic kidney disease and large total body surface area (TBSA) burns should not use nitrofurazone, as topical preparations commonly contain polyethylene glycol, which is readily absorbed through the skin. Rapid absorption of the medication induces increased serum osmolalities and anion gap, leading to death. Symptoms are similar to ethylene glycol poisoning, in that increased serum calcium levels occur concurrently with decreased ionized calcium.
   Paltos later served as a military camp for Gaius Cassius Longinus during the period in which it was part of the province of Syria. The town is mentioned by Greek geographer Strabo in the last quarter of the 1st century BCE as a coastal town of the Aradians and was later mentioned as one of the cities of Syria. When the Province of Syria was divided into Syria Prima and Phoenicia in 194 CE, Paltos marked the border between the two and was included in Syria Prima.
   Chafing may be caused by the salt and residue left behind after sweat evaporates. If sweat is allowed to dry, and exercise is resumed, the salt may intensify the friction and cause further irritation. Other contributing factors include hot weather, sensitive skin, sand from the beach getting into problem areas, and prior skin irritation.
  
  Section::::Prevention and treatment.
   Section::::Determining accuracy.:Defining accuracy.
   Skin maceration
  
  Maceration is defined as the softening and breaking down of skin resulting from prolonged exposure to moisture. It was first described by Jean-Martin Charcot in 1877. Maceration is caused by excessive amounts of fluid remaining in contact with the skin or the surface of a wound for extended periods.
  
  Maceration often occurs when one applies a bandage to everything from a paper cut on the finger to much larger wounds that require professional treatment. One may also notice maceration after wearing non-breathable plastic or latex rubber gloves, which trap moisture against the skin.
   In Peter Craigie's view, "MT’s כָּאֲרִי ('like a lion') presents numerous problems and can scarcely be correct." Reading the consonantal text כארו or כרו, he says that the Septuagint “they pierced my hands and feet” (ὤρυξαν) "may perhaps presuppose a verb כרה, 'to dig,' or כור, 'to pierce, bore'." Craigie notes alternative possibilities for the verb אָרָה (“to pluck, pick clean”), or כרה, “to be shrunken, shriveled”, but follows E. J. Kissane's proposal of an original text כלו, “consumed”, changed to כרו (noting the occasional interchange of ל and ר), with the nuance "my hands and my feet were exhausted".
   Patients suffering from periwound issues may experience burning, itching, tenderness, and pain. Visible and measurable signs include rash, erythema, discoloration, changes in skin texture and temperature.
  
  Section::::Periwound issues.:Causes.
  
  The most common cause of periwound issues is excessive moisture present in the area surrounding the wound. Exudate from heavily draining wounds causes irritation of the periwound that may lead to maceration, excoriation, and otherwise compromise skin integrity.
   Section::::Clearances and Tolerances.:Barrel.:Stress.
   Section::::Climate.
   Osmosis can be demonstrated when potato slices are added to a high salt solution. The water from inside the potato moves out to the solution, causing the potato to shrink and to lose its 'turgor pressure'. The more concentrated the salt solution, the bigger the difference in size and weight of the potato slice.
   The most frequent adverse reactions are nausea, vomiting, diarrhea, abdominal pain, and a feeling of general discomfort. It is also common to experience various sensations in the skin, from crawling or tingling sensations, tenderness of palms and the soles, and numbness of hands, arm, legs or feet. Other skin reactions include skin rash, swelling and stinging sensation. Suramin can also cause loss of appetite and irritability. Suramin causes non-harmful changes in urine during use, specifically making the urine cloudy. It may exacerbate kidney disease.
   It can cause allergic reactions, with numerous large surveys identifying it as being in the "top five" allergens most commonly causing patch test reactions. It may cause inflammation, redness, swelling, soreness, itching, and blisters, including allergic contact dermatitis, stomatitis (inflammation and soreness of the mouth or tongue), cheilitis (inflammation, rash, or painful erosion of the lips, oropharyngeal mucosa, or angles of their mouth), pruritus, hand eczema, generalized or resistant plantar dermatitis, rhinitis, and conjunctivitis.
  
  Section::::Collection.
   Mentioned by the name "Sulem" in 4th century CE works, such as the "Onomasticon" of Eusebius, and by Jerome, both authors situate it 5 Roman miles from Tabor. The village was also known to the Crusaders (12th century CE) under the name "Suna".
  
  Section::::History.:Ottoman era.
   In February 1855 Williams, now a lieutenant-general in the Turkish army, appointed Sandwith inspector-general of hospitals, placing him at the head of the medical staff. Meanwhile, Colonel Henry Atwell Lake was fortifying Kars, and in the beginning of June, when the siege was imminent, Williams and his staff took up their quarters there. During the Siege of Kars, which lasted till the end of November, Sandwith had to contend with cholera and starvation; and after the assault of 29 September he had wounded men, both Turkish and Russian, on his hands. He had to rely mainly on horseflesh broth for his patients.
   BULLET::::- Multiple bee-sting like pains in the affected area
  
  BULLET::::- Occasionally, aching in the groin area or pain spreading across the buttocks
  
  BULLET::::- Usually more sensitive to light touch than to firm pressure
  
  BULLET::::- Hyper sensitivity to heat (warm water from shower feels like it is burning the area)
  
  BULLET::::- Occasionally, patients may complain of itching or a bothersome sensation rather than pain in the affected area.
  
  The entire distribution of the nerve is rarely affected. Usually, the unpleasant sensation(s) affect only part of the skin supplied by the nerve.
  
  Section::::Cause.
   The terms "clearance" and "tolerance" are very often confused and misused. Clearance is the distance between the surfaces of mating parts. Tolerance is the allowable variation of a dimension from its nominal (desired) value.
   In recent years several different chemicals have been used to induce referred pain including bradykinin, substance P, capsaicin, and serotonin. However, before any of these substances became widespread in their use a solution of hypertonic saline was used instead. Through various experiments it was determined that there were multiple factors that correlated with saline administration such as infusion rate, saline concentration, pressure, and amount of saline used. The mechanism by which the saline induces a local and referred pain pair is unknown. Some researchers have commented that it could be due to osmotic differences, however that is not verified.
   Most of the fighting around Nazareth occurred in its satellite villages, particularly in Saffuriya, whose residents put up resistance until largely dispersing following Israeli air raids on 15 July. During the ten days of fighting which occurred between the first and second truce, Nazareth capitulated to Israeli troops during Operation Dekel on 16 July, after little more than token resistance. By then, morale among local militiamen was low and most refused to fight alongside the ALA because of their perceived weakness in the face of Israel's perceived military superiority and the alleged maltreatment of Christian residents and clergy by ALA volunteers. The Muslim mayor of Nazareth, Yusef Fahum requested a halt to all resistance put up by Nazarenes to prevent the town's destruction.
   Sulfacetamide
  
  Sulfacetamide is a sulfonamide antibiotic.
  
  Section::::Uses.
  
  Sulfacetamide 10% topical lotion, sold under the brand name Klaron or Ovace, is approved for the treatment of acne and seborrheic dermatitis. When combined with sulfur, it is sold under the brand names Plexion, Clenia, Prascion, and Avar, which contain 10% sulfacetamide and 5% sulfur.
  