question: How do we know thoughts are created in the brain (and not somewhere else)?
comment: It depends on what you mean by thoughts and created. We can see nerves getting activated in the eye when light hits it. And we can see areas of the brain activate while people are looking at things and how it changes when they look at different things or at nothing. We get sensory input from all over our body, and hormones from different glands affect our moods. But the way thoughts are defined and measured, they only exist as activity in the brain. So stepping on a lego causes a nerve in your foot to send your brain a message that it hurts and it stepped on something, but the thought that you stepped on something occurs in your brain due to receiving the nerve signal. We know this because mri's allow us to see what parts of the brain are active at what times
passages: Section::::Historical origins.:Origins in philosophy.
  
  Philosophers have always been interested in the mind: "the idea that explaining a phenomenon involves understanding the mechanism responsible for it has deep roots in the History of Philosophy from atomic theories in 5th century B.C. to its rebirth in the 17th and 18th century in the works of Galileo, Descartes, and Boyle. Among others, it’s Descartes’ idea that machines humans build could work as models of scientific explanation."
   According to Ryle, mental processes are merely intelligent acts. There are no mental processes that are distinct from intelligent acts. The operations of the mind are not merely represented by intelligent acts, they are the same as those intelligent acts. Thus, acts of learning, remembering, imagining, knowing, or willing are not merely clues to hidden mental processes or to complex sequences of intellectual operations, they are the way in which those mental processes or intellectual operations are defined. Logical propositions are not merely clues to modes of reasoning, they are those modes of reasoning.
   New brain mapping technology, particularly fMRI and PET, allowed researchers to investigate experimental strategies of cognitive psychology by observing brain function. Although this is often thought of as a new method (most of the technology is relatively recent), the underlying principle goes back as far as 1878 when blood flow was first associated with brain function. Angelo Mosso, an Italian psychologist of the 19th century, had monitored the pulsations of the adult brain through neurosurgically created bony defects in the skulls of patients. He noted that when the subjects engaged in tasks such as mathematical calculations the pulsations of the brain increased locally. Such observations led Mosso to conclude that blood flow of the brain followed function.
   Section::::Angelo Mosso and his "human circulation balance".
  
  The desire to understand the human mind has been one of the main desires of philosophers throughout the ages. Questions about thoughts, desires, etcetera have drawn psychologists, computer scientists, philosophers, sociologists and the like together into the new discipline of cognitive science. Non-invasive imaging of the human brain has proven invaluable in this context.
   For example, Aristotle thought the brain was the body’s cooling system and the capacity for intelligence was located in the heart. It has been suggested that the first person to believe otherwise was the Roman physician Galen in the second century AD, who declared that the brain was the source of mental activity, although this has also been accredited to Alcmaeon. However, Galen believed that personality and emotion were not generated by the brain, but rather by other organs. Andreas Vesalius, an anatomist and physician, was the first to believe that the brain and the nervous system are the center of the mind and emotion. Psychology, a major contributing field to cognitive neuroscience, emerged from philosophical reasoning about the mind.
   Historically, most psychophysiologists tended to examine the physiological responses and organ systems innervated by the autonomic nervous system. More recently, psychophysiologists have been equally, or potentially more, interested in the central nervous system, exploring cortical brain potentials such as the many types of event-related potentials (ERPs), brain waves, and utilizing advanced technology such as functional magnetic resonance imaging (fMRI), MRI, PET, MEG, and other neuroimagery techniques.
   Section::::Historical origins.:19th century.:Localizationist view.
   When humans think of an object, such as a screwdriver, many different areas of the brain activate. Marcel Just and his colleague, Tom Mitchell, have used fMRI brain scans to teach a computer to identify the various parts of the brain associated with specific thoughts. This technology also yielded a discovery: similar thoughts in different human brains are surprisingly similar neurologically. To illustrate this, Just and Mitchell used their computer to predict, based on nothing but fMRI data, which of several images a volunteer was thinking about. The computer was 100% accurate, but so far the machine is only distinguishing between 10 images.
   Unlike cognitive neuroscience, which historically has focused on the connection between human brain systems and behavior, the field of MCC has used model organisms, such as mice, to study how molecular (i.e. receptor, kinase activation, phosphatase regulation), intra-cellular (i.e. dendritic processes), and inter-cellular processes (i.e. synaptic plasticity; network representations such as place fields) modulate cognitive function.
   Section::::Historical origins.:Mid-late 20th century.
  
  Several findings in the 20th century continued to advance the field, such as the discovery of ocular dominance columns, recording of single nerve cells in animals, and coordination of eye and head movements. Experimental psychology was also significant in the foundation of cognitive neuroscience. Some particularly important results were the demonstration that some tasks are accomplished via discrete processing stages, the study of attention, and the notion that behavioural data do not provide enough information by themselves to explain mental processes. As a result, some experimental psychologists began to investigate neural bases of behaviour. 
   Cognitive neuroscience addresses the questions of how psychological functions are produced by neural circuitry. The emergence of powerful new measurement techniques such as neuroimaging (e.g., fMRI, PET, SPECT), EEG, MEG, electrophysiology, optogenetics and human genetic analysis combined with sophisticated experimental techniques from cognitive psychology allows neuroscientists and psychologists to address abstract questions such as how cognition and emotion are mapped to specific neural substrates. Although many studies still hold a reductionist stance looking for the neurobiological basis of cognitive phenomena, recent research shows that there is an interesting interplay between neuroscientific findings and conceptual research, soliciting and integrating both perspectives. For example, the neuroscience research on empathy solicited an interesting interdisciplinary debate involving philosophy, psychology and psychopathology. Moreover, the neuroscientific identification of multiple memory systems related to different brain areas has challenged the idea of memory as a literal reproduction of the past, supporting a view of memory as a generative, constructive and dynamic process.
   Cognitive neuroscience is an interdisciplinary area of study that has emerged from neuroscience and psychology. There were several stages in these disciplines that changed the way researchers approached their investigations and that led to the field becoming fully established. 
   Section::::The indirectness of studies of mind and brain.:Single unit recordings.
  
  It is commonly understood in neuroscience that information is encoded in the brain by the firing patterns of neurons. Many of the philosophical questions surrounding the neural code are related to questions about representation and computation that are discussed below. There are other methodological questions including whether neurons represent information through an average firing rate or whether there is information represented by the temporal dynamics. There are similar questions about whether neurons represent information individually or as a population.
  
  Section::::The indirectness of studies of mind and brain.:Computational neuroscience.
   Although the task of cognitive neuroscience is to describe how the brain creates the mind, historically it has progressed by investigating how a certain area of the brain supports a given mental faculty. However, early efforts to subdivide the brain proved to be problematic. The phrenologist movement failed to supply a scientific basis for its theories and has since been rejected. The aggregate field view, meaning that all areas of the brain participated in all behavior, was also rejected as a result of brain mapping, which began with Hitzig and Fritsch’s experimentsG. Fritsch, E. Hitzig, Electric excitability of the cerebrum (Über die elektrische Erregbarkeit des Grosshirns), Epilepsy & Behavior, Volume 15, Issue 2, June 2009, Pages 123-130, ISSN 1525-5050, 10.1016/j.yebeh.2009.03.001. and eventually developed through methods such as positron emission tomography (PET) and functional magnetic resonance imaging (fMRI). Gestalt theory, neuropsychology, and the cognitive revolution were major turning points in the creation of cognitive neuroscience as a field, bringing together ideas and techniques that enabled researchers to make more links between behavior and its neural substrates.
   During the second half of the first millennium BC, the Ancient Greeks developed differing views on the function of the brain. However, due to the fact that Hippocratic doctors did not practice dissection, because the human body was considered sacred, Greek views of brain function were generally uninformed by anatomical study. It is said that it was the Pythagorean Alcmaeon of Croton (6th and 5th centuries BC) who first considered the brain to be the place where the mind was located. According to ancient authorities, "he believed the seat of sensations is in the brain. This contains the governing faculty. All the senses are connected in some way with the brain; consequently they are incapable of action if the brain is disturbed...the power of the brain to synthesize sensations makes it also the seat of thought: The storing up of perceptions gives memory and belief and when these are stabilized you get knowledge." In the 4th century BC, Hippocrates believed the brain to be the seat of intelligence (based, among others before him, on Alcmaeon's work). During the 4th century BC Aristotle thought that, while the heart was the seat of intelligence, the brain was a cooling mechanism for the blood. He reasoned that humans are more rational than the beasts because, among other reasons, they have a larger brain to cool their hot-bloodedness.
   Section::::Historical origins.:19th century.:Mapping the brain.
   BULLET::::- Developments in computer science would lead to parallels being drawn between human thought and the computational functionality of computers, opening entirely new areas of psychological thought. Allen Newell and Herbert Simon spent years developing the concept of artificial intelligence (AI) and later worked with cognitive psychologists regarding the implications of AI. This encouraged a conceptualization of mental functions patterned on the way that computers handled such things as memory storage and retrieval, and it opened an important doorway for cognitivism.
   The first instance of cognitive science experiments being done at an academic institution took place at MIT Sloan School of Management, established by J.C.R. Licklider working within the psychology department and conducting experiments using computer memory as models for human cognition.
   Section::::Historical origins.:19th century.:Aggregate field view.
  
  According to the aggregate field view, all areas of the brain participate in every mental function.
   Chemical catalysts work by creating chemical bonds by bringing existing substances into reaction using intermediaries, and by temporal and spatial conjunction. The prefrontal cortex works similarly upon information processing happening elsewhere in the brain through creating working memory space. This space allows novel intermediary forms of association to be created and held together between different information processing systems in the brain. This process is essential to the formation of symbols and symbol based cognition.
  
  Section::::Concepts.:Neuroscience.:Free cortex.
   According to psychologist and cognitive scientist Steven Pinker, our experiences of the world are represented in our minds as mental images. These mental images can then be associated and compared with others, and can be used to synthesize completely new images. In this view, mental images allow us to form useful theories of how the world works by formulating likely sequences of mental images in our heads without having to directly experience that outcome. Whether other creatures have this capability is debatable.
   These damages change the neural circuits in the brain and cause it to malfunction during basic cognitive processes, such as memory or learning. With the damage, we can compare how the healthy neural circuits are functioning, and possibly draw conclusions about the basis of the affected cognitive processes.
  
  Also, cognitive abilities based on brain development are studied and examined under the subfield of developmental cognitive neuroscience. This shows brain development over time, analyzing differences and concocting possible reasons for those differences.
  
  Theoretical approaches include computational neuroscience and cognitive psychology.
  
  Section::::Historical origins.
   An early story featuring technological transfer of memories and personality from one brain to another is "Intelligence Undying" by Edmond Hamilton, first published in the April 1936 issue of "Amazing Stories". In this story, an elderly scientist named John Hanley explains that when humans are first born, "our minds are a blank sheet except for certain reflexes which we all inherit. But from our birth onward, our minds are affected by all about us, our reflexes are conditioned, as the behaviorists say. All we experience is printed on the sheet of our minds. ... Everything a human being learns, therefore, simply establishes new connections between the nerve cells of the brain. ... As I said, a newborn child has no such knowledge connections in his cortex at all—he has not yet formed any. Now if I take that child immediately after birth and establish in his brain exactly the same web of intricate neurone connections I have built up in my own brain, he will have exactly the same mind, memories, knowledge, as I have ... his mind will be exactly identical with my mind!" He then explains he has developed a technique to do just this, saying "I've devised a way to "scan" my brain's intricate web of neurone connections by electrical impulses, and by means of those impulses to build up an exactly identical web of neurone connections in the infant's brain. Just as a television scanning-disk can break down a complicated picture into impulses that reproduce the picture elsewhere." He adds that the impulses scanning his brain will kill him, but the "counter-impulses" imprinting the same pattern on the baby's brain will not harm him. The story shows the successful transfer of John Hanley's mind to the baby, whom he describes as "John Hanley 2nd", and then skips forward to the year 3144 to depict "John Hanley, 21st" using his advanced technology to become the ruler of the Earth in order to end a war between the two great political powers of the time, and then further ahead to "John Hanley, 416th" helping to evacuate humanity to the planet Mercury in response to the Sun shrinking into a white dwarf. He chooses to remain on Earth awaiting death, so that people would "learn once more to do for themselves, would become again a strong a self-reliant race", with Hanley concluding that he "had been wrong in living as a single super-mind down through the ages. He saw that now, and now he was undoing that wrong."
   Section::::Historical origins.:19th century.
  
  Section::::Historical origins.:19th century.:Phrenology.
   The oldest method of studying the brain is anatomical, and until the middle of the 20th century, much of the progress in neuroscience came from the development of better cell stains and better microscopes. Neuroanatomists study the large-scale structure of the brain as well as the microscopic structure of neurons and their components, especially synapses. Among other tools, they employ a plethora of stains that reveal neural structure, chemistry, and connectivity. In recent years, the development of immunostaining techniques has allowed investigation of neurons that express specific sets of genes. Also, "functional neuroanatomy" uses medical imaging techniques to correlate variations in human brain structure with differences in cognition or behavior.
  