 We purchased our 2000 Sienna about a year ago. It now has 112000 miles on it and runs great!  We have not had any major problems, other than replacing brake pads. It drives very good, like a car, and it's roomy, the seats are very comfortable. It seems very solid and well built. I don't worry about reliability at all- it's a Toyota!! Great gas mileage for something bigger. Very easy to get in and out of with kids ! Very smooth ride. You just cannot beat Toyotas for reliability!!  