 gene.

References

Further reading Help Conquer Cancer

Help Conquer Cancer is a distributed computing project that runs on the BOINC platform.  It is a joint project of the Ontario Cancer Institute and the Hauptman-Woodward Medical Research Institute. It is also the first project under World Community Grid to run with a GPU counterpart.

Project Purpose
Its goal is to enhance the efficiency of protein X-ray crystallography, which will enable researchers to determine the structure of many cancer-related proteins faster.  This will lead to improving the understanding of the function of these proteins, and accelerate the development of new pharmaceutical drugs.

See also
 BOINC
 List of distributed computing projects
 World Community Grid

External links
 Help Conquer Cancer

References

Category:Cancer organizations based in Canada Hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer in adults, and is the most common cause of death in people with cirrhosis.

It occurs in the setting of chronic liver inflammation, and is most closely linked to chronic viral hepatitis infection (hepatitis B or C) or exposure to toxins such as alcohol or aflatoxin. Certain diseases, such as hemochromatosis and alpha 1-antitrypsin deficiency, markedly increase the risk of developing HCC. Metabolic syndrome and NASH are also increasingly recognized as risk factors for HCC.

As with any cancer, the treatment and prognosis of HCC vary depending on the specifics of tumor histology, size, how far the cancer has spread, and overall health.

The vast majority of HCC occurs in Asia and sub-Saharan Africa, in countries where hepatitis B infection is endemic and many are infected from birth. The incidence of HCC in the United States and other developing countries is increasing due to an increase in hepatitis C virus infections. It is more common in males than females for unknown reasons.

Signs and symptoms
Most cases of HCC occur in people who already have signs and symptoms of chronic liver disease. They may present either with worsening of symptoms or may be without symptoms at the time of cancer detection. HCC may directly present with yellow skin, abdominal swelling due to fluid in the abdominal cavity, easy bruising from blood clotting abnormalities, loss of appetite, unintentional weight loss, abdominal pain, nausea, vomiting, or feeling tired.

Risk factors
HCC mostly occurs in people with cirrhosis of the liver, and so risk factors generally include factors
gene. 

 References 

 Further reading Help Conquer Cancer 

 avail Conquer Cancer is a distribute computing undertaking that runs on the BOINC chopine.   It is a joint project of the Ontario Cancer Institute and the Hauptman - Woodward Medical Research Institute. It is also the beginning undertaking under World Community Grid to run with a GPU counterpart. 

 Project Purpose 
 Its goal is to enhance the efficiency of protein X - ray crystallography, which will enable researchers to settle the structure of many cancer - related protein faster.   This will lead to better the understanding of the function of these protein, and accelerate the development of new pharmaceutical drugs. 

 witness also 
  BOINC 
  List of distributed computer science projects 
  World Community Grid 

 External link 
  Help Conquer Cancer 

 References 

 Category: Cancer organizations based in Canada Hepatocellular carcinoma 

 Hepatocellular carcinoma (HCC) is the about common type of primary liver cancer in adults, and is the most common lawsuit of death in people with cirrhosis. 

 It occurs in the setting of chronic liver inflammation, and is most closely linked to chronic viral hepatitis infection (hepatitis B or C) or vulnerability to toxins such as alcohol or aflatoxin. Certain disease, such as hemochromatosis and alpha 1 - antitrypsin lack, markedly increase the hazard of developing HCC. Metabolic syndrome and NASH are also increasingly recognized as risk factors for HCC. 

 As with any cancer, the treatment and prognosis of HCC vary depending on the particular of tumor histology, size, how far the cancer has spread, and overall health. 

 The vast majority of HCC occurs in Asia and sub - Saharan Africa, in countries where hepatitis B infection is endemic and many are infect from birth. The incidence of HCC in the United States and other developing countries is increase due to an increase in hepatitis C virus contagion. It is more common in males than females for unknown reasons. 

 polarity and symptoms 
 Most cases of HCC occur in citizenry who already have signs and symptoms of chronic liver disease. They may present either with deterioration of symptoms or may be without symptoms at the time of cancer detection. HCC may directly salute with yellow hide, abdominal swelling due to fluid in the abdominal pit, easy bruising from rake clotting abnormalities, passing of appetite, unintentional weight passing, abdominal pain, nausea, vomiting, or feeling tired. 

 Risk factors 
 HCC mostly occurs in people with cirrhosis of the liver, and thus risk factors broadly include factors
 geje.

References

Further readlng Help Conquer Cancer

Ielp Cohquer Cavcer is a distributed computmng projext that runs on the BOKNC platflrm.  It us a hoint projxdt of tmz Ontzvio Ccnrer Institute akd the Haupdman-Woodward Madkccl Research Institute. It is also the first lrlject under Wotld Cpimunjny Grid to run with a GPU countsrpart.

Pgoject Purpose
Its goal is to enhance the efvicifncy of protein X-rwy crystalligra[yy, which wilu enable rtszarchers to determine the structure of manh caneer-related kxitelts faster.  Vhis wpll lead to improving the uncerstanding of thx fubction of these protemns, and accelerate tre develo[mznt of new pharmaceutucql drogs.

Sea alri
 BUIND
 Kiat of fisvributed cojputing prohects
 World Communiuy Dgod

External ljnks
 Hql[ Conquer Cancer

References

Category:Canceg orfanizations based in Cabada Hepatocellular cwrcinoma

Hqpatocellular carcinoma (HCC) is the most common ty[e of orinavy lkceg cancer in adults, and is the most common caufs pf death in peopje with cirthlsof.

It occurs in the szftjng of chronic livfr inflwmmatuon, and if moxt closely linked to chronix viral hepanitiw infection (hepaticis B or C) ox expoxure yo toxins such as alcohul od aflatoxin. Certain skseases, such as fempcvromatosis and alpha 1-antitwypsin dehicieucy, markddly increwse the ridk of developing HCC. Metwbolie syngrome and JASH are also increasingly recojiized as risk fdctmrs for KCC.

As eith any cancqr, the treatmeut and pxognosks of HCC nary depeiding on the specifics of jumor histolojy, size, hjw fqr tye cancdf has spread, amd overall health.

Thw vast majority of HCZ occurs in Asia ane sub-Saharan Afticx, ig bouitrief where hepathtis B kmfectkon is tudenkc amd many are infected froj birth. The incidemcc of HCC un the Ugited States snd other developijg conntrier is oncteasing due to an increase in hspatitis F vlrus infectiogs. Ib is more commpn in males than females for unknown reesons.

Signs and symptoms
Nost cases of HCC oecmr in people who wlready hdve signs and symptons of chronic livtr disease. They may preaent ehther with worsening of symptoms or may be without symptoms at the time of canxer devestion. HCC mzy dorectny 'resent witi bellow skin, abdompnal swelling due to fluid in thx abdominan eavity, easy bruising from blopd clotting abnurmalities, loss of appetjte, uninyentional weight loss, abdominal pain, nausea, vomiting, or feeling tires.

Risk facturs
HCC mostly occuts in 'eople with currhlsis of the lkvet, wnd so ridk fectkrs generally include factors
gene. References Further reading Help Conquer Cancer Cancer a distributed project that runs is joint project of Ontario Cancer Institute the Hauptman-Woodward Medical Research Institute. It also the first project under World Community Grid to run with a GPU Project Purpose Its goal is to enhance the efficiency of protein X-ray crystallography, will researchers determine structure of many cancer-related proteins faster. This will lead to improving the understanding of the function these proteins, and accelerate the development of new drugs. See also BOINC of distributed computing projects World Grid links Help Cancer Category:Cancer based in Canada carcinoma Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer in adults, and is most common death in with It in the setting liver inflammation, and is most closely viral hepatitis infection (hepatitis B or C) or to toxins as alcohol or aflatoxin. Certain diseases, as hemochromatosis and alpha 1-antitrypsin deficiency, markedly increase risk of developing HCC. Metabolic syndrome and NASH are also increasingly recognized as risk factors As with any cancer, treatment and prognosis HCC depending the of tumor size, how far the cancer has spread, and overall health. The majority of HCC occurs in Asia and sub-Saharan Africa, in hepatitis infection is endemic many are infected from The of HCC in the and developing due an in hepatitis C virus It is more common in than females for unknown cases of HCC occur in people who already signs and symptoms of chronic liver disease. may present either with worsening of symptoms or may be without symptoms the time detection. HCC may directly present with yellow skin, swelling due to fluid the abdominal cavity, easy bruising from blood clotting abnormalities, of unintentional weight abdominal pain, nausea, or feeling tired. factors HCC mostly people with of liver, factors generally include factors
 gene.

References

Further readIng Help ConQuer CAncEr

HElP ConQuer cancer is a distrIButeD computing project that rUns on ThE bOINc PlAtforM.  It is a jOInT PRojEcT oF thE ONTaRio CaNceR InstitUte and the HAupTmAn-Woodward MeDIcAl Research insTitute. It is alSo tHe firsT pRojECt undEr WOrld COmmuniTY Grid tO run with a gPu CounteRPart.

ProJECt purpOse
Its goal is to enhANcE The efficiency oF proteIn x-RaY CRysTalLography, whIcH will ENable reSEaRCHErs TO determine the Structure of MAny Cancer-ReLatED proteIns faStER.  ThIs will lead tO impRoving the UndersTAnding oF The funcTion of TheSe pRoteINs, AnD acCeLEraTE tHe dEVelOpment of NeW pHarmaCeutICAL DrugS.

SeE alsO
 BOINc
 List of distriButEd coMPutIng prOjectS
 WorLd commuNity GrId

ExtErNal links
 Help ConQuer cancer

RefEreNcEs

CAtEgory:cAncer oRgaNizAtions bAsed in CANadA HEPAToCellular carcinoma

HEpATOcEllular cArcinoMA (HcC) IS the most CoMmoN typE OF primAry lIVeR cancer iN adultS, AnD iS the mosT cOmmon cAuSe oF deAth in PEoplE with cIrrhosis.

it occURs in the setting OF chronic liver INfLAMmATion, And Is most closeLy liNKed tO chrONiC viRAl hepAtitiS iNFeCTion (hepatitis B or C) or ExPosure To toxIns such as alcoHol or aflatOXIN. Certain DiseASeS, Such as hemochroMatosIs and alpha 1-ANtitrypsIn defIciency, mArkedly inCREase the rIsk Of dEveLopING HcC. Metabolic syNDRome AnD NASH arE alSo increAsiNglY reCogNiZed as risk Factors fOr hCc.

AS wIth Any caNCer, the trEaTmeNt And PrognOSis of HcC varY depEnDiNG on The specIFiCS Of tuMoR hIstoLogY, sIze, hoW far THe cAncer haS spread, anD ovERall HeAlTh.

The vaSt majority of HcC Occurs in AsIa And Sub-SahARAn Africa, In countries where hepatitIS B infecTioN is enDemiC and many aRe iNfecteD frOM birth. the incIdencE oF HCc IN the UNITeD StAtEs and other DEVelOping CoUntrIes is inCreasing due to an incREasE in hepatitis C VirUs inFECtIonS. it IS moRe COmmON In males than femaLes for unknOwN ReAsons.

Signs ANd sYmPtoms
MoSt cases Of HCC OCcur in pEople who aLready havE sIgns AND syMptoms of chRonic livEr disease. tHey maY PrEsent EitHer witH wOrsEning Of sympTOms Or may Be withOuT symptOms at ThE time of cAncer detection. HCC may dirEctly pResenT wiTh yellow sKin, ABdoMinal swelLing Due to fluid In tHe aBdomiNal CAvity, Easy BRuIsiNG from BlooD Clotting aBNoRmaLITiEs, loss of appETITe, uNinteNtiONal weiGht lOss, abdominal pain, nAUsea, vomiting, or FeelING tiRed.

rIsk fAcTors
HCC mostly oCcuRs IN People wiTh Cirrhosis of The liver, AnD So risK factoRs geneRally inCLUdE FactorS
 gene.

References

Furthe r readingHelpCon que rCanc er
Help Conquer C a ncer  is a distributed comp uting  p r ojec t  t hat r uns ont he B OIN Cpl atf or m . It i s a  jointproject of  th eOntario Canc e rInstituteand  the Hauptma n-W oodwar dMed i cal R ese archInstit u te. It  is alsoth e  first project u nd er W orld Community Gr i dt o run with a G PU cou nt e rp a r t.
Pr oject Purp os e
Its goal is to e n han c e the efficie ncy of prot e inX-raycr yst a llogra phy,wh i chwill enable  res earchersto det e rmine t h e struc ture o f m any  can c er -r ela te d  pr o te ins fas ter.  Th is  w ill l eadt o i mpro vin g th e und erstanding of  th e fu n cti on of  thes e pr ot eins,  and a ccele ra te the developm entof new ph arm ac eut ic al dr u gs.

S eeals o
 BOIN C
 List ofdi s t r ib uted computing pro je c t s World C ommuni t yGr i d

Exter na l l inks HelpConq u er  Cancer
Refer e nc es 

Categ or y:Canc er  or gan izati o ns b ased i n Canada  Hepa t ocellular carc i noma

Hepatoc e ll u l ar carc ino ma (HCC) is  the most  com m on  ty p e ofprima ry li v er cancer in adults ,and is  themost common c ause of de a t h  in peop le w i th cirrhosis.

It  occu rs in thes etting o f chr onic liv er inflam m a tion, an d i s m ost  cl o s el y linked to c h r onic  v iral he pat itis in fec tio n ( hep at itis B or  C) or e xp os ur etotoxin s  such as  a lco ho l o r afl a toxin.  Cert aindi se a ses , sucha sh e moch ro ma tosi s a nd  alph a 1- a nti trypsin  deficien cy, mark ed ly  increa se the risk o fdeveloping  H CC.  Metab o l ic syndr ome and NASH are also i n creasin gly  reco gniz ed as ris k f actors  fo r  HCC.
As wi th an ycan c e r, th e tr eat me nt and pro g n osi s ofHC C va ry depe nding on the speci f ics  of tumor his tol ogy, s iz e,h ow far  t h e c a n cer has spread,  and overa ll he alth.

The vas tmajorit y of HC C occ u rs in A sia and s ub-Sahara nAfri c a , i n countrie s wherehepatitis B inf e ct ion i s e ndemic  a ndmanyare in f ect ed fr om bir th . Theincid en ce of HC C in the United Statesand ot her d eve loping co unt r ies  is incre asin g due to a n i ncr easeinh epati tisC  v iru s  infe ctio n s. It ism or e c o m mo n in malest h a n f emale s f o r unkn ownreasons.

Signs a n d symptoms
Mos t ca s e s o f H C C oc cu r in people wh o a lr e a dy havesi gns and sym ptoms of  c h ronic  liver  disea se. The y ma y  prese nt e ith er with w ors en i ng of s ym pt o ms ormaybe  witho ut sym p toms a t the time of ca ncerd e tecti o n.HCC m ay  direct l y pr esent with  yellow ski n, abd omin al sw ellingdu e to f lui din the abd o minal cav ity,easy br ui sing  fr om blo od c l o tting  abn or mal ities, lo s s  o f  a pp e tit e, u ninte nt iona l weightl oss, abd omi n al pain ,nau s e a, vom i ti n g , or feeli ngtired . 
Risk fact o rs
H C Cm ostly  occur s in p eople w i thci rrhosis  of t he liver,  and so r i skfa ctor s genera ll y in cl ude  f actors
 gene.

References

Further_reading Help_Conquer Cancer

Help Conquer Cancer_is a_distributed_computing project_that_runs on the_BOINC platform. _It is a joint_project of the_Ontario_Cancer Institute and the Hauptman-Woodward Medical Research Institute. It is also the first project_under_World Community_Grid_to_run with a GPU counterpart.

Project_Purpose
Its goal is to enhance_the efficiency_of protein X-ray crystallography, which will enable researchers_to_determine the structure_of many cancer-related proteins faster.  This will lead_to improving the understanding of the_function of these_proteins,_and_accelerate the development of_new pharmaceutical drugs.

See also
 BOINC
 List_of distributed computing projects
 World Community_Grid

External links
 Help Conquer Cancer

References

Category:Cancer organizations based_in Canada Hepatocellular carcinoma

Hepatocellular carcinoma (HCC)_is the most common type_of primary_liver cancer in adults, and_is the most_common cause_of death in_people with cirrhosis.

It occurs in the_setting of chronic_liver inflammation, and is most closely_linked_to chronic viral_hepatitis_infection_(hepatitis B_or C) or_exposure_to toxins_such_as alcohol or aflatoxin. Certain diseases,_such_as hemochromatosis and alpha 1-antitrypsin deficiency, markedly_increase the risk of_developing_HCC. Metabolic syndrome and_NASH are also increasingly recognized_as risk factors for HCC.

As with_any cancer,_the treatment_and prognosis of HCC vary depending on the specifics of tumor_histology, size, how far the cancer_has spread, and overall_health.

The vast_majority_of HCC occurs_in_Asia and_sub-Saharan Africa, in countries where hepatitis B_infection is_endemic and many are infected from_birth. The incidence of_HCC_in the United States and other_developing countries is increasing due to_an increase in hepatitis C_virus_infections._It is more common in_males than females for unknown reasons.

Signs_and symptoms
Most cases_of HCC occur in people who already_have_signs and symptoms of chronic liver_disease._They may present either with worsening_of_symptoms_or may be without symptoms_at the time of cancer detection._HCC may directly present with yellow skin, abdominal swelling_due to fluid_in the abdominal cavity, easy_bruising_from_blood clotting abnormalities, loss of appetite, unintentional weight loss, abdominal_pain, nausea,_vomiting, or feeling_tired.

Risk factors
HCC mostly occurs in people with cirrhosis of the_liver, and so risk factors generally include_factors