The principle treatment for DPD-deficient patients with severe acute 5-FU reactions is supportive care; however, the administration of thymidine potentially may reverse severe 5-FU-induced neurologic symptoms such as encephalopathy and coma.
coma
5-FU
encephalopathy
5-FU
neurologic symptoms
5-FU
severe acute 5-FU reactions
5-FU