Three patients, in whom tumour overkill by cytotoxic treatment, including high dose methotrexate with folinic acid rescue, resulted in the 'phosphate shower syndrome' (hyper-uricaemia, hyperkalaemia and hyperphosphataemia with hypocalcaemia and tetany, with metabolic acidosis and acute renal impairment) are described.
hypocalcaemia
folinic acid
hyperkalaemia
methotrexate
hyperphosphataemia
folinic acid
tetany
methotrexate
acute renal impairment
folinic acid
tetany
folinic acid
hyper-uricaemia
methotrexate
hyperkalaemia
folinic acid
phosphate shower syndrome
folinic acid
hyperphosphataemia
methotrexate
hyper-uricaemia
folinic acid
hypocalcaemia
methotrexate
metabolic acidosis
folinic acid
acute renal impairment
methotrexate
metabolic acidosis
methotrexate
phosphate shower syndrome
methotrexate