Instruct: Identify the main and secondary category of Arxiv papers based on the titles and abstracts
Query: Structural characteristics in network control of molecular multiplex
  networks   Numerous real-world systems can be naturally modeled as multilayer networks,
enabling an efficient way to characterize those complex systems. Much evidence
in the context of system biology indicated that the collections between
different molecular networks can dramatically impact the global network
functions. Here, we focus on the molecular multiplex networks coupled by the
transcriptional regulatory network (TRN) and protein-protein interaction (PPI)
network, exploring the controllability and energy requiring in these types of
molecular multiplex networks. We find that the driver nodes tend to avoid
essential or pathogen-related genes. Yet, imposing the external inputs to these
essential or pathogen-related genes can remarkably reduce the energy cost,
implying their crucial role in network control. Moreover, we find that lower
minimal driver nodes as well as energy requiring are associated with
disassortative coupling between TRN and PPI networks. Our findings in several
species provide comprehensive understanding of genes' roles in biology and
network control.

13
The categories of this paper are: quant-ph
23
The categories of this paper are: solv-int
24
The categories of this paper are: dg-ga
30
The categories of this paper are: q-alg
33
The categories of this paper are: plasm-ph
9
The categories of this paper are: nlin
2
The categories of this paper are: math
27
The categories of this paper are: comp-gas
31
The categories of this paper are: ao-sci
21
The categories of this paper are: adap-org
15
The categories of this paper are: nucl-ex
16
The categories of this paper are: stat
34
The categories of this paper are: chem-ph
37
The categories of this paper are: supr-con
20
The categories of this paper are: acc-phys
1
The categories of this paper are: cs