Instruct: Identify the main and secondary category of Arxiv papers based on the titles and abstracts
Query: Predicting Rich Drug-Drug Interactions via Biomedical Knowledge Graphs
  and Text Jointly Embedding   Minimizing adverse reactions caused by drug-drug interactions has always been
a momentous research topic in clinical pharmacology. Detecting all possible
interactions through clinical studies before a drug is released to the market
is a demanding task. The power of big data is opening up new approaches to
discover various drug-drug interactions. However, these discoveries contain a
huge amount of noise and provide knowledge bases far from complete and
trustworthy ones to be utilized. Most existing studies focus on predicting
binary drug-drug interactions between drug pairs but ignore other interactions.
In this paper, we propose a novel framework, called PRD, to predict drug-drug
interactions. The framework uses the graph embedding that can overcome data
incompleteness and sparsity issues to achieve multiple DDI label prediction.
First, a large-scale drug knowledge graph is generated from different sources.
Then, the knowledge graph is embedded with comprehensive biomedical text into a
common low dimensional space. Finally, the learned embeddings are used to
efficiently compute rich DDI information through a link prediction process. To
validate the effectiveness of the proposed framework, extensive experiments
were conducted on real-world datasets. The results demonstrate that our model
outperforms several state-of-the-art baseline methods in terms of capability
and accuracy.

20
The categories of this paper are: acc-phys
25
The categories of this paper are: patt-sol
30
The categories of this paper are: q-alg
14
The categories of this paper are: math-ph
10
The categories of this paper are: q-bio
9
The categories of this paper are: nlin
4
The categories of this paper are: cond-mat
7
The categories of this paper are: hep-th
15
The categories of this paper are: nucl-ex
35
The categories of this paper are: mtrl-th
19
The categories of this paper are: eess
8
The categories of this paper are: hep-ex
28
The categories of this paper are: alg-geom
24
The categories of this paper are: dg-ga
5
The categories of this paper are: gr-qc
2
The categories of this paper are: math