Instruct: Identify the main and secondary category of Arxiv papers based on the titles and abstracts
Query: The Information Capacity of Specific Interactions   Specific interactions are a hallmark feature of self-assembly and
signal-processing systems in both synthetic and biological settings.
Specificity between components may arise from a wide variety of physical and
chemical mechanisms in diverse contexts, from DNA hybridization to
shape-sensitive depletion interactions. Despite this diversity, all systems
that rely on interaction specificity operate under the constraint that
increasing the number of distinct components inevitably increases off-target
binding. Here we introduce `capacity', the maximal information encodable using
specific interactions, to compare specificity across diverse experimental
systems, and to compute how specificity changes with physical parameters. Using
this framework, we find that `shape'-coding of interactions has higher capacity
than chemical (`color') coding because the strength of off-target binding is
strongly sublinear in binding site size for shapes while being linear for
colors. We also find that different specificity mechanisms, such as shape and
color, can be combined in a synergistic manner, giving a capacity greater than
the sum of the parts.

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The categories of this paper are: q-alg
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The categories of this paper are: dg-ga
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The categories of this paper are: math-ph
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The categories of this paper are: bayes-an
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The categories of this paper are: chem-ph
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The categories of this paper are: q-fin
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The categories of this paper are: hep-th
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The categories of this paper are: plasm-ph
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The categories of this paper are: nucl-ex
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The categories of this paper are: hep-lat
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The categories of this paper are: nlin
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The categories of this paper are: eess
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The categories of this paper are: mtrl-th
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The categories of this paper are: funct-an
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The categories of this paper are: comp-gas
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The categories of this paper are: adap-org