Instruct: Identify the main and secondary category of Arxiv papers based on the titles and abstracts
Query: MITK-ModelFit: A generic open-source framework for model fits and their
  exploration in medical imaging -- design, implementation and application on
  the example of DCE-MRI   Many medical imaging techniques utilize fitting approaches for quantitative
parameter estimation and analysis. Common examples are pharmacokinetic modeling
in DCE MRI/CT, ADC calculations and IVIM modeling in diffusion-weighted MRI and
Z-spectra analysis in chemical exchange saturation transfer MRI. Most available
software tools are limited to a special purpose and do not allow for own
developments and extensions. Furthermore, they are mostly designed as
stand-alone solutions using external frameworks and thus cannot be easily
incorporated natively in the analysis workflow. We present a framework for
medical image fitting tasks that is included in MITK, following a rigorous
open-source, well-integrated and operating system independent policy. Software
engineering-wise, the local models, the fitting infrastructure and the results
representation are abstracted and thus can be easily adapted to any model
fitting task on image data, independent of image modality or model. Several
ready-to-use libraries for model fitting and use-cases, including fit
evaluation and visualization, were implemented. Their embedding into MITK
allows for easy data loading, pre- and post-processing and thus a natural
inclusion of model fitting into an overarching workflow. As an example, we
present a comprehensive set of plug-ins for the analysis of DCE MRI data, which
we validated on existing and novel digital phantoms, yielding competitive
deviations between fit and ground truth. Providing a very flexible environment,
our software mainly addresses developers of medical imaging software that
includes model fitting algorithms and tools. Additionally, the framework is of
high interest to users in the domain of perfusion MRI, as it offers
feature-rich, freely available, validated tools to perform pharmacokinetic
analysis on DCE MRI data, with both interactive and automatized batch
processing workflows.

34
The categories of this paper are: chem-ph
5
The categories of this paper are: gr-qc
16
The categories of this paper are: stat
29
The categories of this paper are: funct-an
18
The categories of this paper are: econ
32
The categories of this paper are: atom-ph
36
The categories of this paper are: cmp-lg
22
The categories of this paper are: chao-dyn
31
The categories of this paper are: ao-sci
1
The categories of this paper are: cs
8
The categories of this paper are: hep-ex
35
The categories of this paper are: mtrl-th
13
The categories of this paper are: quant-ph
19
The categories of this paper are: eess
28
The categories of this paper are: alg-geom
30
The categories of this paper are: q-alg