Instruct: Identify the main and secondary category of Arxiv papers based on the titles and abstracts
Query: New Candidates for Furin Inhibition as Probable Treat for COVID-19:
  Docking Output   Furin is a serine protease that takes part in the processing and activation
of the host cell pre-proteins. The enzyme also plays an important role in the
activation of several viruses like the newly emerging SARS-CoV-2 virus that
causes COVID-19 disease with a high rate of virulence and mortality. Unlike
viral enzymes, furin owns a constant sequence and active site characteristics
and seems to be a better target for drug design for COVID-19 treatment.
Considering furin active site as receptor and some approved drugs from
different classes including antiviral, antibiotics, and anti protozoa/anti
parasites with suspected beneficial effects on COVID-19, as ligands we have
carried out docking experiments in HEX software to pickup those capable to bind
furin active site with high affinity and suggest them as probable candidates
for clinical trials assessments. Our docking experiments show that saquinavir,
nelfinavir, and atazanavir with cumulative inhibitory effects of 2.52, 2.16,
and 2.13 respectively seem to be the best candidates for furin inhibition even
in severe cases of COVID-19 as adjuvant therapy, while clarithromycin,
niclosamide, and erythromycin with cumulative inhibitory indices of 1.97, 1.90,
and 1.84 respectively with lower side effects than antiviral drugs could be
suggested as prophylaxes for the first stage of COVID-19 as a promising treat.

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The categories of this paper are: atom-ph
20
The categories of this paper are: acc-phys
30
The categories of this paper are: q-alg
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The categories of this paper are: chem-ph
17
The categories of this paper are: q-fin
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The categories of this paper are: mtrl-th
25
The categories of this paper are: patt-sol
22
The categories of this paper are: chao-dyn
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The categories of this paper are: bayes-an
6
The categories of this paper are: astro-ph
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The categories of this paper are: adap-org
16
The categories of this paper are: stat
3
The categories of this paper are: physics
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The categories of this paper are: cmp-lg
11
The categories of this paper are: hep-lat
12
The categories of this paper are: nucl-th