Instruct: Identify the main and secondary category of Arxiv papers based on the titles and abstracts
Query: The coupling of thermodynamics with the organizational water-protein
  intra-dynamics driven by the H-bonds dissipative potential of cluster water   The Red cell-Hb-CSF functions as a sensor adapting response to Hb
heterotropic equilibriums. At the lungs O2 and Mg2+, each one increasing
affinity for the other stabilize the relax (R) form [(O2)4Hb(Mg)2].(H2O)R. At
tissue level, the inclusion of H+ and 2,3-DPG excludes O2 and Mg2+ to stabilize
the tense (T) form 2,3-DPG-deoxyHb-(H2O)T. Both senses are integrated into a
cycle T into R and R into T, without involving a direct reversal. The
dissipative potential of water cluster (H2O)n interacts with the hydrophilic
asymmetries of Hb, to restrict randomness of the kinetic sense implicated in a
single peak for activation energy (Ea). The hydration shells could sequence an
enhanced Ea into several peaks, to sequentially activate transitions states.
Hence, changes in dipole state, sliding, pKa, n-H-bonds, etc., could became
concatenated for vectoriality. (H2O)n by the loss of H-bonds couple with to the
hydration turnover of proteins and ions to result in incomplete water cluster
(H2O)n*, with a lower-n. (H2O)n* became a carrier of heat/entropy into the
cerebrospinal fluid (CSF) which has to be replaced 3.7 times per day. OxyHb
formation involves sliding-down of alpha vs beta chains, to shift alpha1 and
alpha2 Pro 44 into allowing the entrance of a fully hydrated
[Mg.(H2O)6](H2O)12-14(2+) (or Zn2+) into the hydrophilic beta2-alpha1 and
beta1-alpha2 interfaces. OxyHb pKa of 6.4 leads to H+-dissociation increasing
negative charge of R-groups. This at beta2-alpha1 sequence two tetradentate
chelates, first an Mg2+, bonding with beta2 His 92 and a second Mg2+ with
alpha1 His 87, to cooperatively release hindrance. The interconversion of
oxy-to-deoxyHb, pKa=8, leads to the amphoteric imidazole to became positively
charged and proximal histidines return into hindrance position, releasing the
incomplete hydrated Mg.(H2O)inc(2+) and O2 into CSF.

35
The categories of this paper are: mtrl-th
20
The categories of this paper are: acc-phys
34
The categories of this paper are: chem-ph
8
The categories of this paper are: hep-ex
13
The categories of this paper are: quant-ph
2
The categories of this paper are: math
7
The categories of this paper are: hep-th
29
The categories of this paper are: funct-an
9
The categories of this paper are: nlin
3
The categories of this paper are: physics
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The categories of this paper are: supr-con
11
The categories of this paper are: hep-lat
18
The categories of this paper are: econ
31
The categories of this paper are: ao-sci
12
The categories of this paper are: nucl-th
16
The categories of this paper are: stat