Instruct: Identify the main and secondary category of Arxiv papers based on the titles and abstracts
Query: Joint analysis of structural connectivity and cortical surface features:
  correlates with mild traumatic brain injury   Mild traumatic brain injury (mTBI) is a complex syndrome that affects up to
600 per 100,000 individuals, with a particular concentration among military
personnel. About half of all mTBI patients experience a diverse array of
chronic symptoms which persist long after the acute injury. Hence, there is an
urgent need for better understanding of the white matter and gray matter
pathologies associated with mTBI to map which specific brain systems are
impacted and identify courses of intervention. Previous works have linked mTBI
to disruptions in white matter pathways and cortical surface abnormalities.
Herein, we examine these hypothesized links in an exploratory study of joint
structural connectivity and cortical surface changes associated with mTBI and
its chronic symptoms. Briefly, we consider a cohort of 12 mTBI and 26 control
subjects. A set of 588 cortical surface metrics and 4,753 structural
connectivity metrics were extracted from cortical surface regions and diffusion
weighted magnetic resonance imaging in each subject. Principal component
analysis (PCA) was used to reduce the dimensionality of each metric set. We
then applied independent component analysis (ICA) both to each PCA space
individually and together in a joint ICA approach. We identified a stable
independent component across the connectivity-only and joint ICAs which
presented significant group differences in subject loadings (p<0.05,
corrected). Additionally, we found that two mTBI symptoms, slowed thinking and
forgetfulness, were significantly correlated (p<0.05, corrected) with mTBI
subject loadings in a surface-only ICA. These surface-only loadings captured an
increase in bilateral cortical thickness.

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The categories of this paper are: hep-lat
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The categories of this paper are: quant-ph
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The categories of this paper are: patt-sol
5
The categories of this paper are: gr-qc
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The categories of this paper are: alg-geom
3
The categories of this paper are: physics
33
The categories of this paper are: plasm-ph
0
The categories of this paper are: hep-ph
6
The categories of this paper are: astro-ph
31
The categories of this paper are: ao-sci
8
The categories of this paper are: hep-ex
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The categories of this paper are: solv-int
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The categories of this paper are: chao-dyn
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The categories of this paper are: atom-ph
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The categories of this paper are: q-fin
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The categories of this paper are: bayes-an