Instruct: Identify the main category of Biorxiv papers based on the titles and abstracts
Query: Translational control of fungal gene expression during the wheat-Fusarium graminearum interaction O_LITo date, translational regulation of key genes controlling infection-related processes in fungal pathogens during their interactions with plants has not been studied. Here, we employed ribosome profiling (ribo-seq) to study translational responses and how such responses are coordinated with transcriptional changes in the fungal pathogen Fusarium graminearum (Fg), which causes Fusarium head blight (FHB), a destructive disease of cereal crops worldwide.
C_LIO_LITranscription and translation were not always coordinated with approximately 22% of Fg genes showing a discordant relationship during wheat infection. Nitrite reductase, which we show here as an important component of fungal virulence, is only regulated at the translational level in Fg. In addition, more than 1000 new open reading frames (ORFs), many of which are short and highly conserved, were identified in the Fg genome.
C_LIO_LILike in higher eukaryotes, translation is controlled by upstream ORFs (uORFs) in Fg during infection. Similarly, miRNAs control both transcription and translation in Fg during wheat infection. However, Fgdicer2-dependent miRNAs do not have a significant effect on transcriptional gene expression at the global outset.
C_LIO_LIThe ribo-seq study undertaken here for the first time in any fungal pathogen discovered novel insights about the biology of an important plant pathogen.
C_LI
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The categories of this paper are: evolutionary
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The categories of this paper are: molecular
31
The categories of this paper are: paleontology
20
The categories of this paper are: pharmacology
11
The categories of this paper are: cognition
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The categories of this paper are: neuroscience
22
The categories of this paper are: physiology
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The categories of this paper are: bioinformatics
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The categories of this paper are: biophysics
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The categories of this paper are: education
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The categories of this paper are: immunology
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The categories of this paper are: biology
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The categories of this paper are: and
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The categories of this paper are: ecology
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The categories of this paper are: communication
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The categories of this paper are: bioengineering