Instruct: Identify the main and secondary category of Arxiv papers based on the titles and abstracts
Query: Fast whole-slide cartography in colon cancer histology using superpixels
  and CNN classification   Automatic outlining of different tissue types in digitized histological
specimen provides a basis for follow-up analyses and can potentially guide
subsequent medical decisions. The immense size of whole-slide-images (WSI),
however, poses a challenge in terms of computation time. In this regard, the
analysis of non-overlapping patches outperforms pixelwise segmentation
approaches, but still leaves room for optimization. Furthermore, the division
into patches, regardless of the biological structures they contain, is a
drawback due to the loss of local dependencies. We propose to subdivide the WSI
into coherent regions prior to classification by grouping visually similar
adjacent pixels into superpixels. Afterwards, only a random subset of patches
per superpixel is classified and patch labels are combined into a superpixel
label. We propose a metric for identifying superpixels with an uncertain
classification and evaluate two medical applications, namely tumor area and
invasive margin estimation and tumor composition analysis. The algorithm has
been developed on 159 hand-annotated WSIs of colon resections and its
performance is compared to an analysis without prior segmentation. The
algorithm shows an average speed-up of 41% and an increase in accuracy from
93.8% to 95.7%. By assigning a rejection label to uncertain superpixels, we
further increase the accuracy by 0.4%. Whilst tumor area estimation shows high
concordance to the annotated area, the analysis of tumor composition highlights
limitations of our approach. By combining superpixel segmentation and patch
classification, we designed a fast and accurate framework for whole-slide
cartography that is AI-model agnostic and provides the basis for various
medical endpoints.

15
The categories of this paper are: nucl-ex
4
The categories of this paper are: cond-mat
6
The categories of this paper are: astro-ph
25
The categories of this paper are: patt-sol
36
The categories of this paper are: cmp-lg
5
The categories of this paper are: gr-qc
34
The categories of this paper are: chem-ph
16
The categories of this paper are: stat
3
The categories of this paper are: physics
29
The categories of this paper are: funct-an
21
The categories of this paper are: adap-org
31
The categories of this paper are: ao-sci
8
The categories of this paper are: hep-ex
14
The categories of this paper are: math-ph
17
The categories of this paper are: q-fin
10
The categories of this paper are: q-bio