Instruct: Identify the main and secondary category of Arxiv papers based on the titles and abstracts
Query: Searching beyond the usual papillomavirus suspects in squamous
  carcinomas of the vulva, penis and head and neck   Human Papillomaviruses (HPVs) are involved in the etiology of anogenital and
head and neck cancers. The HPV DNA prevalence greatly differs by anatomical
site. Indeed, the high rates of viral DNA prevalence in anal and cer-vical
carcinomas contrast with the lower fraction of cancer cases attributable to
HPVs in other anatomical sites, chiefly the vulva, the penis and head and neck.
Here we analyzed 2635 Formalin Fixed Paraffin Embedded surgical samples that
had previously tested negative for the presence of HPVs DNA using the
SPF10/DEIA procedure, in order to identify the presence of other PVs not
explicitly targeted by standard molecular epidemiologic approaches. All samples
were reanalyzed using five broad-PV PCR primer sets (CP1/2, FAP6064/FAP64,
SKF/SKR, MY9/MY11, MFI/MFII) targeting the main PV main clades. In head and
neck carcinoma samples (n = 1141), we recovered DNA from two BetaHPVs, namely
HPV20 and HPV21, and from three cutaneous AlphaPVs, namely HPV2, HPV57 and
HPV61. In vulvar squamous cell carcinoma samples (n = 902), we found one of the
samples containing DNA of one cutaneous HPV, namely HPV2, and 29 samples
contained DNA from essentially mucosal HPVs. In penile squamous cell carcinoma
samples (n = 592), we retrieved the DNA of HPV16 in 16 samples. Our results
show first that the SPF10/DEIA is very sensitive, as we recovered only 2.1%
(55/2635) false negative results; second, that although the DNA of cutaneous
HPVs can be detected in cancer samples, their relative contribution remains
anyway minor (0.23%; 6/2635) and may be neglected for screening and vaccination
purposes; and third, their contribution to malignancy is not necessarily
warranted and needs to be elucidated.

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The categories of this paper are: dg-ga
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The categories of this paper are: eess
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The categories of this paper are: patt-sol
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The categories of this paper are: nucl-ex
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The categories of this paper are: physics
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The categories of this paper are: quant-ph
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The categories of this paper are: bayes-an
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The categories of this paper are: astro-ph
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The categories of this paper are: solv-int
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The categories of this paper are: nlin
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The categories of this paper are: hep-th
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The categories of this paper are: cmp-lg
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The categories of this paper are: comp-gas
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The categories of this paper are: ao-sci
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The categories of this paper are: adap-org
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The categories of this paper are: alg-geom