Instruct: Identify the main and secondary category of Arxiv papers based on the titles and abstracts
Query: A comprehensive protocol for manual segmentation of the human claustrum
  and its sub-regions using high-resolution MRI   The claustrum (Cl) is a thin grey matter structure located in the center of
each brain hemisphere. Cl has been hypothesized as a central hub of the brain
for multisensory/sensorimotor integration, consciousness, and attention.
Accumulating evidence has suggested that Cl might be important in the
development of severe neurological and psychiatric symptoms including epileptic
seizures and psychosis. However, the specifics of the roles of Cl in human
epilepsy and psychosis are largely unknown, primarily due to methodological
limitations related to the thin morphology of Cl that is challenging to
delineate accurately using conventional methods. The goal of this work is to
develop noninvasive multimodal neuroimaging methods to delineate Cl anatomy by
utilizing a large healthy adult high resolution (0.7mm3) T1-weighted MRI
collected as part of the Washington University-Minnesota Consortium Human
Connectome Project (WU-Minn HCP). We developed a comprehensive manual
segmentation protocol to delineate Cl based on a cellular level brain atlas.
The protocol involves detailed guidelines to delineate the three subregions of
Cl, including the dorsal, ventral, and temporal Cl that can be parcellated
based on a geometric method. As demonstrated in a representative result, Cl is
large in its anterior-posterior, and the dorsal-ventral extent. Also, the
volume is comparable to that of the amygdala. It is required to assess the
reliability of the protocol so that it can be used for future anatomical
studies of neuropsychiatric disorders, including epilepsy and schizophrenia.

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The categories of this paper are: patt-sol
23
The categories of this paper are: solv-int
15
The categories of this paper are: nucl-ex
8
The categories of this paper are: hep-ex
35
The categories of this paper are: mtrl-th
22
The categories of this paper are: chao-dyn
3
The categories of this paper are: physics
17
The categories of this paper are: q-fin
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The categories of this paper are: atom-ph
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The categories of this paper are: supr-con
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The categories of this paper are: q-alg
7
The categories of this paper are: hep-th
31
The categories of this paper are: ao-sci
4
The categories of this paper are: cond-mat
6
The categories of this paper are: astro-ph
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The categories of this paper are: bayes-an