Instruct: Identify the main and secondary category of Arxiv papers based on the titles and abstracts
Query: Molecular behavior of DNA in a cell-sized compartment coated by lipids   The behavior of long DNA molecules in a cell-sized confined space was
investigated. We prepared water-in-oil droplets covered by phospholipids, which
mimic the inner space of a cell, following the encapsulation of DNA molecules
with unfolded coil and folded globule conformations. Microscopic observation
revealed that the adsorption of coiled DNA onto the membrane surface depended
on the size of the vesicular space. Globular DNA showed a cell-size-dependent
unfolding transition after adsorption on the membrane. Furthermore, when DNA
interacted with a two-phase membrane surface, DNA selectively adsorbed on the
membrane phase, such as an ordered or disordered phase, depending on its
conformation. We discuss the mechanism of these trends by considering the free
energy of DNA together with a polyamine in the solution. The free energy of our
model was consistent with the present experimental data. The cooperative
interaction of DNA and polyamines with a membrane surface leads to the
size-dependent behavior of molecular systems in a small space. These findings
may contribute to a better understanding of the physical mechanism of molecular
events and reactions inside a cell.

35
The categories of this paper are: mtrl-th
12
The categories of this paper are: nucl-th
16
The categories of this paper are: stat
11
The categories of this paper are: hep-lat
28
The categories of this paper are: alg-geom
34
The categories of this paper are: chem-ph
26
The categories of this paper are: bayes-an
6
The categories of this paper are: astro-ph
33
The categories of this paper are: plasm-ph
24
The categories of this paper are: dg-ga
17
The categories of this paper are: q-fin
31
The categories of this paper are: ao-sci
27
The categories of this paper are: comp-gas
8
The categories of this paper are: hep-ex
7
The categories of this paper are: hep-th
32
The categories of this paper are: atom-ph