Instruct: Identify the main category of Biorxiv papers based on the titles and abstracts
Query: Cell population migration cycle and response to environmental pH in Bacillus subtilis Microbial populations are ubiquitous and some form a robust, multicellular structure called biofilm that protects the cells from environmental damage. The dispersion cycle is critical for controlling the population of important target microbes (both pathogenic and beneficial). Here, we show that the hysteresis of Bacillus subtilis cell-type regulation with respect to auto-inducing signal strength triggers the migration cycle of the cell population. We investigate migration cycle and its dependence on environmental conditions by quantitative analysis of cyclically expanding, concentric circular colonies. Next, we construct an input/output model that controls cell types in response to environmental conditions and signal density. On the basis of this model, we propose a migration cycle model for cell populations. The proposed model will widely predict biofilm-related phenomena and provide the basis for the description of highly self-regulating multicellular systems.
8
The categories of this paper are: genomics
23
The categories of this paper are: immunology
13
The categories of this paper are: animal
0
The categories of this paper are: genetics
19
The categories of this paper are: epidemiology
10
The categories of this paper are: and
15
The categories of this paper are: developmental
3
The categories of this paper are: evolutionary
4
The categories of this paper are: neuroscience
30
The categories of this paper are: scientific
14
The categories of this paper are: biophysics
32
The categories of this paper are: zoology
29
The categories of this paper are: education
9
The categories of this paper are: synthetic
22
The categories of this paper are: physiology
7
The categories of this paper are: ecology