Instruct: Identify the main and secondary category of Arxiv papers based on the titles and abstracts
Query: Can one predict DNA Transcription Start Sites by studying bubbles?   It has been speculated that bubble formation of several base-pairs due to
thermal fluctuations is indicatory for biological active sites. Recent
evidence, based on experiments and molecular dynamics (MD) simulations using
the Peyrard-Bishop-Dauxois model, seems to point in this direction. However,
sufficiently large bubbles appear only seldom which makes an accurate
calculation difficult even for minimal models. In this letter, we introduce a
new method that is orders of magnitude faster than MD. Using this method we
show that the present evidence is unsubstantiated.

32
The categories of this paper are: atom-ph
4
The categories of this paper are: cond-mat
30
The categories of this paper are: q-alg
24
The categories of this paper are: dg-ga
12
The categories of this paper are: nucl-th
18
The categories of this paper are: econ
34
The categories of this paper are: chem-ph
1
The categories of this paper are: cs
23
The categories of this paper are: solv-int
21
The categories of this paper are: adap-org
14
The categories of this paper are: math-ph
31
The categories of this paper are: ao-sci
10
The categories of this paper are: q-bio
5
The categories of this paper are: gr-qc
13
The categories of this paper are: quant-ph
33
The categories of this paper are: plasm-ph