Instruct: Identify the main and secondary category of Arxiv papers based on the titles and abstracts
Query: From augmented microscopy to the topological transformer: a new approach
  in cell image analysis for Alzheimer's research   Cell image analysis is crucial in Alzheimer's research to detect the presence
of A$\beta$ protein inhibiting cell function. Deep learning speeds up the
process by making only low-level data sufficient for fruitful inspection. We
first found Unet is most suitable in augmented microscopy by comparing
performance in multi-class semantics segmentation. We develop the augmented
microscopy method to capture nuclei in a brightfield image and the transformer
using Unet model to convert an input image into a sequence of topological
information. The performance regarding Intersection-over-Union is consistent
concerning the choice of image preprocessing and ground-truth generation.
Training model with data of a specific cell type demonstrates transfer learning
applies to some extent.
  The topological transformer aims to extract persistence silhouettes or
landscape signatures containing geometric information of a given image of
cells. This feature extraction facilitates studying an image as a collection of
one-dimensional data, substantially reducing computational costs. Using the
transformer, we attempt grouping cell images by their cell type relying solely
on topological features. Performances of the transformers followed by SVM,
XGBoost, LGBM, and simple convolutional neural network classifiers are inferior
to the conventional image classification. However, since this research
initiates a new perspective in biomedical research by combining deep learning
and topology for image analysis, we speculate follow-up investigation will
reinforce our genuine regime.

18
The categories of this paper are: econ
29
The categories of this paper are: funct-an
20
The categories of this paper are: acc-phys
15
The categories of this paper are: nucl-ex
21
The categories of this paper are: adap-org
6
The categories of this paper are: astro-ph
28
The categories of this paper are: alg-geom
8
The categories of this paper are: hep-ex
7
The categories of this paper are: hep-th
34
The categories of this paper are: chem-ph
0
The categories of this paper are: hep-ph
14
The categories of this paper are: math-ph
30
The categories of this paper are: q-alg
31
The categories of this paper are: ao-sci
13
The categories of this paper are: quant-ph
5
The categories of this paper are: gr-qc