Instruct: Identify the main and secondary category of Arxiv papers based on the titles and abstracts
Query: Bacterial chromosome organization II: few special cross-links, cell
  confinement, and molecular crowders play the pivotal roles   Using a bead-spring model of bacterial DNA polymers of {\em C. crescentus}
and {\em E. coli} we show that just $33$ and $38$ effective cross-links at
special positions along the chain contour of the DNA can lead to the
large-scale organization of the DNA polymer, where confinement effects of the
cell walls play a key role in the organization. The positions of the $33$
cross-links along the chain contour are chosen from the contact map data of
{\em C. crescentus}. We represent $1000$ base pairs as a coarse-grained monomer
in our bead-spring flexible ring polymer model of the DNA. Thus a $4017$ beads
on a flexible ring polymer represents the {\em C. crescentus} DNA with $4017$
kilo-base pairs. Choosing suitable parameters from our preceding study, we also
incorporate the role of molecular crowders and the ability of the chain to
release topological constraints. We validate our prediction of the organization
of the {\em C. crescentus} with available experimental contact map data and
also give a prediction of the approximate positions of different segments
within the cell in 3D. For the {\em E. coli} chromosome with $4.6$ million base
pairs, we need around $38$ effective cross-links with cylindrical confinement
to organize the chromosome. We also predict the 3D organization of the {\em E.
coli} chromosome segments within the cylinder which represents the cell wall.

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The categories of this paper are: quant-ph
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The categories of this paper are: q-fin
14
The categories of this paper are: math-ph
26
The categories of this paper are: bayes-an
35
The categories of this paper are: mtrl-th
23
The categories of this paper are: solv-int
33
The categories of this paper are: plasm-ph
31
The categories of this paper are: ao-sci
7
The categories of this paper are: hep-th
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The categories of this paper are: dg-ga
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The categories of this paper are: gr-qc
1
The categories of this paper are: cs
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The categories of this paper are: hep-lat
25
The categories of this paper are: patt-sol
28
The categories of this paper are: alg-geom
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The categories of this paper are: nucl-ex