Instruct: Identify the main and secondary category of Arxiv papers based on the titles and abstracts
Query: Loss of least-loaded class in asexual populations due to drift and
  epistasis   We consider the dynamics of a non-recombining haploid population of finite
size which accumulates deleterious mutations irreversibly. This ratchet like
process occurs at a finite speed in the absence of epistasis, but it has been
suggested that synergistic epistasis can halt the ratchet. Using a diffusion
theory, we find explicit analytical expressions for the typical time between
successive clicks of the ratchet for both non-epistatic and epistatic fitness
functions. Our calculations show that the inter-click time is of a scaling form
which in the absence of epistasis gives a speed that is determined by size of
the least-loaded class and the selection coefficient. With synergistic
interactions, the ratchet speed is found to approach zero rapidly for arbitrary
epistasis. Our analytical results are in good agreement with the numerical
simulations.

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The categories of this paper are: hep-ph
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The categories of this paper are: acc-phys
11
The categories of this paper are: hep-lat
30
The categories of this paper are: q-alg
23
The categories of this paper are: solv-int
24
The categories of this paper are: dg-ga
1
The categories of this paper are: cs
3
The categories of this paper are: physics
2
The categories of this paper are: math
36
The categories of this paper are: cmp-lg
35
The categories of this paper are: mtrl-th
22
The categories of this paper are: chao-dyn
19
The categories of this paper are: eess
7
The categories of this paper are: hep-th
14
The categories of this paper are: math-ph
6
The categories of this paper are: astro-ph