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This is beautiful. I would totally pick one up if they were available, especially that blue one.
You should design some where the main design elements are not in the centre, as that's where most would put the keyboard.  I like ones where the design elements are biased to the side(s) so you can still see them when a keyboard in in place.  A good example is the soya milk deskmat, or the something like the CosmiCats deskmats... or GMK Agent-01  Ideally though, as most may also use a seperate numpad on the right, a bias to the left would be good too. >

I always consider it, most of my designs have the layout on the right (the mouse side) however in this one it was a bit more complex, even so I consider that the fish on the right is between the mouse and the keyboard so that it is present most of the time, thank you very much! >

This is sick