How to play vs the 1...e6 and 2...d6 Pawn structure? I've noticed that sometimes beginners play 1. e4 e6 2. d4 d6 as Black.

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1. e4 e6 2. d4 d6


As strange as it may seem, I find it difficult to play vs this neglected defense. Is it better to increase central control with an early 3. c4 (neglecting piece development) or to follow-up with 3. Nc3? Then, assuming Black continues to neglect the center, would you follow-up with an early f2-f4, or would you prefer piece development with an early Nf3? Any ideas would be much appreciated.
By choosing these moves black is giving you a lot options, and you are free to choose what you prefer with a good game.

Most aggressive is probably Nc3 followed by f4, Nf3, Bd3, 0-0, and looking for attack on the king's side, with f5 or e5 depending on what black does.

But more positional approach with c4 is totally fine. 

Another alternative is to fianchetto the light squared bishop, and maybe eventually play f4. 

Just play the game that fits your style.