What should you do in this position? I no longer have this game, although I do remember losing it. Here's the setup of the game, with White to move:

[fen "2b1kb1r/r5pp/8/p1pQBp2/qn1P1P2/6P1/4P2P/2R1KR2 w - - 0 1"]
White can safely resign. He is down 2 pieces without compensation and Black has a passed pawn.

Now, Black's King is not secure, so if the White Q could get a check in, it is possible the Queen and Bishop could be a threat.  However, I see nothing here that makes me think White can get anything going.

So Qc4 to keep the Queen close to the action while keeping an eye on g8 to prevent castling. This pins the Knight on b4 though I don't know that it matters much.

If White gets time, he could consider Kf2.  This will connect the White rooks in preparation for Rfd1, after which White shoves the d-pawn down Black's gullet.  If Black takes it, all the better.

But White really is doomed.