TCS Research Frontier with Huge Practical and Industrial Impact on our Society While CS theorists pursue the beauty and unity of their mathematical theories, their results can have a practical and industrial impact.

As we know, P versus NP is often talked about with its relation to public crypto. systems. Moreover, streaming algorithms often directly lead to industrial benefits. 

Is there any possible research direction that would satisfy the following conditions? 

(1)Solving problems in this area of TCS would lead to a fundamental change in our society.

(2)It would be required to understand other academic subjects (such as physics or electronics) to solve problems related to this TCS field. 

I am afraid that this question is not appropriate for this stack exchange, but please forgive me if it is.
There are many examples of theoretical research that had a big impact on society, e.g., the RSA cryptosystem, the algorithm behind Google search, the algorithmic ideas behind Akamai, etc.
But the thing with basic research is that it's hard to know in advance what's going to be influential, when and how.

One potential candidate could be quantum computing, which has strong ties to both physics and electronics, and could make a huge difference (allowing efficient simulations of quantum systems, breaking RSA, and more). However, it's hard to know when quantum computers will be built (if at all).