How to distinguish PICTURE OF ME and PICTURE OF MINE in Chinese? This is a PICTURE OF ME.
This is a PICTURE OF MINE.

Both can be translated to

这是我的图片
这是我的照片 can be interpreted as "It is a photo of me" or "It is a photo that belong to me"

To avoid confusion, you can write:


这照片是我的 = "this photo is mine"
这照片中的人是我  = "the person in this photo is me"
这照片上的人是我  = "the person on this photo is me"


照片 = photo; picture

图片= graphic; picture