Does Revelation 22:19 apply to the whole Biblical canon or only the Book of Revelation? Revelation 22:19  KJV


  And if any man shall take away from the words of the book of this prophecy, God shall take away his part out of the book of life, and out of the holy city, and from the things which are written in this book. 


When I first began to study the Bible in earnest, I became intrigued by the Apocrypha, and when I spoke to my pastor about it, he ignored my questions. Some other sources, however, indicated that those apocryphal books had been rejected, because they conflicted with that particular verse.

Through further study, it became apparent that the argument had no real backing. Since all of the books of the Bible were not written by the same person, and over a very long time, and they were not even compiled or even authorized until some years later.
Revelation 22:19 (NIV)
  
  And if anyone takes words away from this scroll of prophecy, God
  will take away from that person any share in the tree of life and in
  the Holy City, which are described in this scroll.


"THIS SCROLL"

Literally, "this scroll" refers to the scroll which Apostle John was writing. John was a prisoner in Patmos Island and on the Lord's Day(Sunday), he saw Jesus and Jesus commanded him to write down what was shown to him.


  On the Lord’s Day I was in the Spirit, and I heard behind me a loud
  voice like a trumpet, which said: “Write on a scroll what you see
  and send it to the seven churches: to Ephesus, Smyrna, Pergamum,
  Thyatira, Sardis, Philadelphia and Laodicea.” (Revelation 1:10-11, NIV)


There are many reasons why "this scroll" cannot refer to the whole Bible.


The whole Bible would not fit into a single scroll: The scrolls in the first century were big and thick. The Five Books of Moses were usually on a single large scroll but other books were on separate scrolls. For instance, when Jesus returned from the wilderness after the Baptism, Jesus read from the scroll of prophet Isaiah, which was a single scroll (source: Pulpit Commentary on Luke 4:17).


  and the scroll of the prophet Isaiah was handed to him. Unrolling it,
  he found the place where it is written... (Luke 4:17, NIV)
  The New Testament was not yet Canonized: When John was writing these words, know that even the Book of Revelation was still in the process of development. John still had to send it to the seven churches first and then it would take few months to write it down in the existing scrolls that they had, which doubtfully was not a complete New Testament canon. From the History of Development of the New Testament canon, the Canonization was a gradual process, which didn't take place in the first century but later, 2nd or 3rd century.