MakerBot replicator 2x glitches I have access to a MakerBot Replicator 2X which I use to try to print ABS + dissoluble (both are MakerBot's original filaments). It is really a pain and the filaments most often gets clogged (80% of the prints have to be thrown away). I a supposed to use the printer in a professional context, but at the moment it is really problematic and I feel pressure going up...

I have initially tried the default parameters provided by the machine for known filaments (ABS: 230°C / dissoluble: 250°C / plate: 110°C + 0.1mm layers). As the nozzle got clogged I have made many other attempts with varying parameters and up to (250°C / 270°C / 135°C), which slightly improves things but is far from being really usable.

Any idea of where this comes from?
 - ABS being notoriously difficult to print?
 - The Replicator 2x being old tech?
 - A parameters problem?

Any advice on what I should do to improve the situation?
I don't have a profile that has settings for the dissolvable filament anymore, but this is one I use for thin layers (second extruder at 232C my first extruder isn't working so just ignore that one).

You may want to try printing small simple objects with each extruder independently first to confirm that you have good settings, then try both together after you know you have good settings. ABS is a pain but mostly for warping and sticking to the build plate. The dissolvable filament I believe is PLA if you're using Makerbot materials.

{
       "_attached_extruders" : [ "mk8", "mk8" ],
       "_bot" : "replicator2x",
       "_extruders" : [ 0 ],
       "_materials" : [ "abs", "abs" ],
       "adjacentFillLeakyConnections" : false,
       "adjacentFillLeakyDistanceRatio" : 0,
       "anchorExtrusionAmount" : 5.0,
       "anchorExtrusionSpeed" : 2.0,
       "anchorWidth" : 2.0,
       "backlashEpsilon" : 0.050,
       "backlashFeedback" : 0.90,
       "backlashX" : 0.0,
       "backlashY" : 0.090,
       "bedZOffset" : 0.0,
       "bridgeAnchorMinimumLength" : 0.80,
       "bridgeAnchorWidth" : 0.80,
       "bridgeMaximumLength" : 80.0,
       "bridgeSpacingMultiplier" : 1.0,
       "coarseness" : 9.999999747378752e-005,
       "commentClose" : "",
       "commentOpen" : ";",
       "computeVolumeLike2_1_0" : false,
       "defaultExtruder" : 0,
       "defaultRaftMaterial" : 0,
       "defaultSupportMaterial" : 0,
       "description" : "External Definition",
       "doAnchor" : true,
       "doBacklashCompensation" : false,
       "doBreakawaySupport" : true,
       "doBridging" : true,
       "doDynamicSpeed" : false,
       "doDynamicSpeedGradually" : true,
       "doDynamicSpeedInteriorShells" : false,
       "doDynamicSpeedOutermostShell" : true,
       "doExponentialDeceleration" : false,
       "doExternalSpurs" : true,
       "doFixedLayerStart" : false,
       "doFixedShellStart" : true,
       "doInfills" : true,
       "doInsets" : true,
       "doInternalSpurs" : false,
       "doMixedRaft" : false,
       "doMixedSupport" : false,
       "doOutlines" : true,
       "doPrintLayerMessages" : false,
       "doPrintProgress" : true,
       "doPurgeWall" : false,
       "doRaft" : true,
       "doSplitLongMoves" : true,
       "doSupport" : true,
       "doSupportUnderBridges" : false,
       "endGcode" : "",
       "exponentialDecelerationMinSpeed" : 0.0,
       "extruderProfiles" : [
          {
             "bridgesExtrusionProfile" : "bridges",
             "feedDiameter" : 1.820000052452087,
             "feedstockMultiplier" : 0.9300000000000001,
             "firstLayerExtrusionProfile" : "firstLayer",
             "firstLayerRaftExtrusionProfile" : "firstLayerRaft",
             "floorSurfaceFillsExtrusionProfile" : "floorSurfaceFills",
             "infillsExtrusionProfile" : "infill",
             "insetsExtrusionProfile" : "insets",
             "layerHeight" : 0.20,
             "maxSparseFillThickness" : 0.20,
             "nozzleDiameter" : 0.40,
             "outlinesExtrusionProfile" : "outlines",
             "raftBaseExtrusionProfile" : "raftBase",
             "raftExtrusionProfile" : "raft",
             "restartExtraDistance" : 0.0,
             "restartExtraDistance2" : 0,
             "restartExtraRate" : 25.0,
             "restartExtraRate2" : -1,
             "restartRate" : 25.0,
             "restartRate2" : 25,
             "retractDistance" : 1.700000047683716,
             "retractDistance2" : 0,
             "retractRate" : 25.0,
             "retractRate2" : 50,
             "roofSurfaceFillsExtrusionProfile" : "roofSurfaceFills",
             "sparseRoofSurfaceFillsExtrusionProfile" : "sparseRoofSurfaceFills",
             "toolchangeRestartDistance" : 18.50,
             "toolchangeRestartRate" : 6.0,
             "toolchangeRetractDistance" : 19.0,
             "toolchangeRetractRate" : 6.0
          },
          {
             "bridgesExtrusionProfile" : "bridges",
             "feedDiameter" : 1.769999980926514,
             "feedstockMultiplier" : 0.9300000000000001,
             "firstLayerExtrusionProfile" : "firstLayer",
             "firstLayerRaftExtrusionProfile" : "firstLayerRaft",
             "floorSurfaceFillsExtrusionProfile" : "floorSurfaceFills",
             "infillsExtrusionProfile" : "infill",
             "insetsExtrusionProfile" : "insets",
             "layerHeight" : 0.20,
             "maxSparseFillThickness" : 0.20,
             "nozzleDiameter" : 0.40,
             "outlinesExtrusionProfile" : "outlines",
             "raftBaseExtrusionProfile" : "raftBase",
             "raftExtrusionProfile" : "raft",
             "restartExtraDistance" : 0.0,
             "restartExtraDistance2" : 0,
             "restartExtraRate" : 25.0,
             "restartExtraRate2" : -1,
             "restartRate" : 25.0,
             "restartRate2" : 25,
             "retractDistance" : 1.399999976158142,
             "retractDistance2" : 0,
             "retractRate" : 25.0,
             "retractRate2" : 50,
             "roofSurfaceFillsExtrusionProfile" : "roofSurfaceFills",
             "sparseRoofSurfaceFillsExtrusionProfile" : "sparseRoofSurfaceFills",
             "toolchangeRestartDistance" : 18.50,
             "toolchangeRestartRate" : 6.0,
             "toolchangeRetractDistance" : 19.0,
             "toolchangeRetractRate" : 6.0
          }
       ],
       "extruderTemp0" : 228,
       "extruderTemp1" : 232,
       "extrusionProfiles" : {
          "bridges" : {
             "fanSpeed" : 0.50,
             "feedrate" : 40.0
          },
          "firstLayer" : {
             "fanSpeed" : 0.50,
             "feedrate" : 10.0
          },
          "firstLayerRaft" : {
             "fanSpeed" : 0.50,
             "feedrate" : 50.0
          },
          "floorSurfaceFills" : {
             "fanSpeed" : 0.50,
             "feedrate" : 40.0
          },
          "infill" : {
             "fanSpeed" : 0.50,
             "feedrate" : 40.0
          },
          "insets" : {
             "fanSpeed" : 0.50,
             "feedrate" : 40.0
          },
          "outlines" : {
             "fanSpeed" : 0.50,
             "feedrate" : 10.0
          },
          "raft" : {
             "fanSpeed" : 0.50,
             "feedrate" : 90.0
          },
          "raftBase" : {
             "fanSpeed" : 0.50,
             "feedrate" : 10.0
          },
          "roofSurfaceFills" : {
             "fanSpeed" : 0.50,
             "feedrate" : 90.0
          },
          "sparseRoofSurfaceFills" : {
             "fanSpeed" : 0.50,
             "feedrate" : 90.0
          }
       },
       "fixedLayerStartX" : 0.0,
       "fixedLayerStartY" : 0.0,
       "fixedShellStartDirection" : 215.0,
       "floorSolidThickness" : 0,
       "floorSurfaceThickness" : 0,
       "floorThickness" : 1.0,
       "gridSpacingMultiplier" : 1.0,
       "infillDensity" : 0.3000000119209290,
       "infillOrientationInterval" : 90,
       "infillOrientationOffset" : 0,
       "infillOrientationRange" : 90,
       "infillShellSpacingMultiplier" : 0.70,
       "insetDistanceMultiplier" : 1.0,
       "jsonToolpathOutput" : false,
       "layerHeight" : 0.1199999973177910,
       "leakyConnectionsAdjacentDistance" : 0.0,
       "maxConnectionLength" : 10.0,
       "maxSparseFillThickness" : 0.1000000014901161,
       "maxSpurWidth" : 0.50,
       "minLayerDuration" : 5.0,
       "minLayerHeight" : 0.010,
       "minRaftBaseGap" : 0.0,
       "minSpeedMultiplier" : 0.30,
       "minSpurLength" : 0.40,
       "minSpurWidth" : 0.120,
       "minThickInfillImprovement" : 1.0,
       "modelFillProfiles" : {},
       "numberOfShells" : 2,
       "platformTemp" : 110,
       "purgeBucketSide" : 4.0,
       "purgeWallBaseFilamentWidth" : 2.0,
       "purgeWallBasePatternLength" : 10.0,
       "purgeWallBasePatternWidth" : 8.0,
       "purgeWallModelOffset" : 2.0,
       "purgeWallPatternWidth" : 2.0,
       "purgeWallSpacing" : 1.0,
       "purgeWallWidth" : 0.50,
       "purgeWallXLength" : 30.0,
       "raftAligned" : true,
       "raftBaseAngle" : 0.0,
       "raftBaseDensity" : 0.6999999880790710,
       "raftBaseLayers" : 1,
       "raftBaseRunGapRatio" : 0.8000000119209290,
       "raftBaseRunLength" : 15.0,
       "raftBaseThickness" : 0.3000000119209290,
       "raftBaseWidth" : 2.50,
       "raftExtraOffset" : 0.0,
       "raftFillProfiles" : {},
       "raftInterfaceAngle" : 45.0,
       "raftInterfaceDensity" : 0.3000000119209290,
       "raftInterfaceLayers" : 1,
       "raftInterfaceThickness" : 0.2700000107288361,
       "raftInterfaceWidth" : 0.4000000059604645,
       "raftModelSpacing" : 0.3499999940395355,
       "raftOutset" : 4.0,
       "raftSurfaceAngle" : 0.0,
       "raftSurfaceLayers" : 3,
       "raftSurfaceShellSpacingMultiplier" : 0.6999999880790710,
       "raftSurfaceShells" : 2,
       "raftSurfaceThickness" : 0.1400000005960465,
       "roofAnchorMargin" : 0.40,
       "roofSolidThickness" : 0,
       "roofSurfaceThickness" : 0,
       "roofThickness" : 1.0,
       "shellsLeakyConnections" : false,
       "solidFillOrientationInterval" : 90,
       "solidFillOrientationOffset" : -45,
       "solidFillOrientationRange" : 90,
       "sparseInfillPattern" : "hexagonal",
       "splitMinimumDistance" : 0.40,
       "spurOverlap" : 0.0010,
       "startGcode" : "",
       "startPosition" : {
          "x" : -112,
          "y" : -73.0,
          "z" : 0
       },
       "supportAligned" : false,
       "supportAngle" : 30.0,
       "supportDensity" : 0.2000000029802322,
       "supportExcessive" : false,
       "supportExtraDistance" : 0.50,
       "supportFillProfiles" : {},
       "supportLayerHeight" : 0.2000000029802322,
       "supportLeakyConnections" : false,
       "supportModelSpacing" : 0.2000000029802322,
       "supportRoofModelSpacing" : 0.4000000059604645,
       "thickLayerThreshold" : 0,
       "thickLayerVolumeMultiplier" : 1,
       "travelSpeedXY" : 150.0,
       "travelSpeedZ" : 23.0,
       "version" : "3.9.4"
    }