Layer lifted and separated from ESD PLA I'm using the default Ultimaker Cura draft profile but with the nozzle temp at 220&nbsp;&deg;C because this is a special ESD filament.

All was going well after some troubleshooting thanks to some users on 3DPrinting.SE but this happened over night:

What would cause an entire layer to lift off the main body, continue to print and then turn to spaghetti?

The red circled part was supposed to be part of the blue outline.
The spool kept getting caught on itself and tightening. I unrolled some of it and rewound it and the print came out perfect. @anttix was almost correct with the clog theory.