What can be an example for an organic cofactor ?
For example , the multienzyme complex pyruvate dehydrogenase at the junction of glycolysis and the citric acid cycle requires five organic cofactors and one metal ion : loosely bound thiamine pyrophosphate ( TPP ) , covalently bound lipoamide and flavin adenine dinucleotide ( FAD ) , and the cosubstrates nicotinamide adenine dinucleotide ( NAD + ) and coenzyme A ( CoA ) , and a metal ion ( Mg2 + ) .