Plutonium
Which substance does uranium-238 decay into first?
Manhattan Project
The second line of development pursued by the Manhattan Project used the fissile element plutonium. Although small amounts of plutonium exist in nature, the best way to obtain large quantities of the element is in a nuclear reactor, in which natural uranium is bombarded by neutrons. The uranium-238 is transmuted into uranium-239, which rapidly decays, first into neptunium-239 and then into plutonium-239. Only a small amount of the uranium-238 will be transformed, so the plutonium must be chemically separated from the remaining uranium, from any initial impurities, and from fission products.