Space-Time Variation of Physical Constants and the Equivalence Principle
  Location dependence of physical parameters such as the electromagnetic fine structure constant and Newton's G produce body accelerations which violate universality of free fall rates testable with laboratory and space experiments. Theoretically related cosmological time variation of these same parameters are also constrained by experiments such as lunar laser ranging, and these time variations produce accelerations of bodies relative to a preferred cosmological frame. 
Kenneth Nordtvedt