def loadtwocol(infile):
    """
    load two columns file,
    save to a dict,
    with the first as keys the second as values
    """
    kvdict = {}
    with open(infile) as f:
        for nline, line in enumerate(f):
            line = line.strip()
            if line: # to exclude blank line
                k, v = line.split('\t')
                kvdict[k] = v
    return kvdict