def norm_TC(df, scalar_factor = 1):
    """Very basic normalization. Total Counts. scalar_factor =  1

    Parameters
    ----------
    df : pandas.DataFrame
        Dataframe with the raw reads.
    scalar_factor : int, float
        Integer or float, can be diversity of the smaples or the avg of read across
        the whole dataset

    Returns
    -------
    pandas.DataFrame
        with the colun nReads, Normilized reads

    """
    df['nReads'] = ( df['Reads'] / df['Reads'].sum() ) * scalar_factor

    return df