def get_strand(start, end):
    """
    Checks the start and end coordinates of a sequence and returns -1 if the
    sequence comes from the 3' strand and 1 if it comes from the 5' strand

    start: An integer indicating sequence start location
    end: An integer indicating sequence end location
    """

    # -
    if start > end:
        return -1
    # +
    elif start <= end:
        return 1

    return 0