def any_heterozygous(genotypes):
    """Determine if any of the genotypes are heterozygous
    
    Parameters
    ----------
    genoytypes : container
        Genotype for each sample of the variant being considered
    
    Returns
    -------
    bool
        True if at least one sample is heterozygous at the variant being
        considered, otherwise False
    """
    
    return bool(
        {'0|1', '1|0', '0/1'}
        & {genotype.split(':')[0] for genotype in genotypes}
    )