def get_orientation(read1, read2):
    """
    Return relative orientation of read pairs. Assumes read pairs have
    been ordered such that read 1 is five prime of read 2.
    """

    if read1.is_reverse:
        if read2.is_reverse:
            orientation = "Same-reverse"
        else:
            orientation = "Outward"
    else:
        if read2.is_reverse:
            orientation = "Inward"
        else:
            orientation = "Same-forward"
    return orientation