def _delete_full_gap_columns(full_gaps, sequence, start, end):
    """
    Return the sequence without the full gap columns.

    >>> full_gaps = [False, True, False, False, False, True]
    >>> _delete_full_gap_columns(full_gaps, "Q-V-Q-", 1, 6)
    'V-Q'
    """
    cleaned_seq = []
    for i in range(start, end):
        if not full_gaps[i]:
            cleaned_seq.append(sequence[i])
    return ''.join(cleaned_seq)