Upgrade SQLAlchemy and Flask
Upgrade SQLAlchemy and Flask

https://nvd.nist.gov/vuln/detail/CVE-2018-1000656
https://nvd.nist.gov/vuln/detail/CVE-2019-7548
https://nvd.nist.gov/vuln/detail/CVE-2019-7164

Duke-GCB/iMADS,Duke-GCB/iMADS,Duke-GCB/iMADS,Duke-GCB/TF-DNA-PredictionsDB,Duke-GCB/iMADS,Duke-GCB/TF-DNA-PredictionsDB,Duke-GCB/TF-DNA-PredictionsDB,Duke-GCB/TF-DNA-PredictionsDB