Intramuscular lorazepam versus pentobarbital premedication: a comparison of patient sedation, anxiolysis, and recall.
In a double-blind, controlled study in 40 veterans, IM lorazepam was significantly superior to IM pentobarbital as a preoperative sedative and in ability to suppress the memory of events of the operative day. A trend was noted (not statistically in this small series) toward greater patient acceptance of lorazepam. No important adverse effects or changes in vital signs occurred with either agent.
Intramuscular lorazepam versus pentobarbital premedication: a comparison of patient sedation, anxiolysis, and recall. In a double-blind, controlled study in 40 veterans, IM lorazepam was significantly superior to IM pentobarbital as a preoperative sedative and in ability to suppress the memory of events of the operative day. A trend was noted (not statistically in this small series) toward greater patient acceptance of lorazepam. No important adverse effects or changes in vital signs occurred with either agent.