Microbial acetylation of M factor of virginiamycin.
The M component of virginiamycin was found to be modified by whole cells or cell-free enzyme preparations of a Staphylococcus aureus strain. It was shown that this reaction proceeds by enzymatic acetylation of the secondary alcoholic function of the molecule, followed by a rapid chemical degradation of the O-acetylated product.
Microbial acetylation of M factor of virginiamycin. The M component of virginiamycin was found to be modified by whole cells or cell-free enzyme preparations of a Staphylococcus aureus strain. It was shown that this reaction proceeds by enzymatic acetylation of the secondary alcoholic function of the molecule, followed by a rapid chemical degradation of the O-acetylated product.