Sensitivity of formation of adenovirus specific tumour antigen to leukocyte interferon.
The effect of various concentrations of chicken leukocyte interferon was examined on the expression of adenovirus tumour (T) antigen in chick embryo cells. The inhibition of T antigen formation was dependent on the multiplicity of infection. The reduction of T antigen-producing cells was greater when interferon was applied before and after virus infection.
Sensitivity of formation of adenovirus specific tumour antigen to leukocyte interferon. The effect of various concentrations of chicken leukocyte interferon was examined on the expression of adenovirus tumour (T) antigen in chick embryo cells. The inhibition of T antigen formation was dependent on the multiplicity of infection. The reduction of T antigen-producing cells was greater when interferon was applied before and after virus infection.