[Properties of chlorotetrolic acid and its ester as possible protein acetylenic reagents].
Chlorotetrolic acid and, even better, the corresponding methyl ester react under mild conditions with different functional groups. The relative ease with which the same nucleophile adds to the triple bond and substitutes the chlorine was studied and the stability of the addition products was compared.
[Properties of chlorotetrolic acid and its ester as possible protein acetylenic reagents]. Chlorotetrolic acid and, even better, the corresponding methyl ester react under mild conditions with different functional groups. The relative ease with which the same nucleophile adds to the triple bond and substitutes the chlorine was studied and the stability of the addition products was compared.