[Changes in the electrical activity of myocardial fibers following heart transplantation to under the skin of the ear in mice].
Intracellular rest and action potentials (RP and AP, respectively) of mouse heart graft were reduced on the 3rd--4th days after the transplantation as compared with the intracellular potentials of newborn mice. Beginning from the 5th--6th days there occurred a gradual increase of the intracellular potentials of amplitude. The firt 7--8 days, both in the case of allograft and heterograft, the changes in the intracellular activity were the same. Then in heterograft there occurred a repeated reduction of the RP and AP amplitude of the graft myocardial fibers, this apparently being connected with the development of the rejection reaction. In the allograft samples the amplitude of the intracellular potentials approached by the end of the first month after the graft with RP and AP values of the recipient's myocardial fibers.
[Changes in the electrical activity of myocardial fibers following heart transplantation to under the skin of the ear in mice]. Intracellular rest and action potentials (RP and AP, respectively) of mouse heart graft were reduced on the 3rd--4th days after the transplantation as compared with the intracellular potentials of newborn mice. Beginning from the 5th--6th days there occurred a gradual increase of the intracellular potentials of amplitude. The firt 7--8 days, both in the case of allograft and heterograft, the changes in the intracellular activity were the same. Then in heterograft there occurred a repeated reduction of the RP and AP amplitude of the graft myocardial fibers, this apparently being connected with the development of the rejection reaction. In the allograft samples the amplitude of the intracellular potentials approached by the end of the first month after the graft with RP and AP values of the recipient's myocardial fibers.