A model independent method for estimating the in vivo release rate constant of a drug from its oral formulations.
A simple equation by which the first-order release rate constant of a drug from its oral formulation can be calculated is derived. The derivation is independent of any hypothetical concepts of drug distribution or elimination.
A model independent method for estimating the in vivo release rate constant of a drug from its oral formulations. A simple equation by which the first-order release rate constant of a drug from its oral formulation can be calculated is derived. The derivation is independent of any hypothetical concepts of drug distribution or elimination.