Effect of PGE1 on lipogenesis in perfused rat liver.
In perfused livers of 24 hour-fasted rats, PGE1 (prostaglandin E1) infused continuously into the perfusate, was found to cause a 45% increase in the incorporation of 1-14C acetate into liver fatty acids. PGE1 was found to have no effect, however, on the activity of the key lipogenic enzymes.
Effect of PGE1 on lipogenesis in perfused rat liver. In perfused livers of 24 hour-fasted rats, PGE1 (prostaglandin E1) infused continuously into the perfusate, was found to cause a 45% increase in the incorporation of 1-14C acetate into liver fatty acids. PGE1 was found to have no effect, however, on the activity of the key lipogenic enzymes.