[Physicochemical properties of 7-phenylacetamidodesacetoxy-cephalosporanic acid].
7-phenylacetamidodesacetoxycephalosporanic acid was prepared by transformation of benzylpenicillin. The acid was subjected to potentiometric titration and investigation of its electrophoretic mobility at wide pH ranges. The data of the potentiometric titration and electrophoresis were used for calculation of the acid ionization constant. Minimum solubility of the acid was determined and the curve of its solubility at wide pH ranges was estimated.
[Physicochemical properties of 7-phenylacetamidodesacetoxy-cephalosporanic acid]. 7-phenylacetamidodesacetoxycephalosporanic acid was prepared by transformation of benzylpenicillin. The acid was subjected to potentiometric titration and investigation of its electrophoretic mobility at wide pH ranges. The data of the potentiometric titration and electrophoresis were used for calculation of the acid ionization constant. Minimum solubility of the acid was determined and the curve of its solubility at wide pH ranges was estimated.